Aspikor - (Aspikor) umarnin don amfani
Magungunan ba tare da bambanci ba yana hana aikin enzyme cyclooxygenase 1 da 2 (tsara tsarin haɗin prostaglandins).
Aspicor na miyagun ƙwayoyi yana da analgesic (analgesia), anti-inflammatory da antipyretic effects.
Aiki mai aiki acetylsalicylic acid yana rage jinkirin samuwar prostaglandins, a ƙarƙashin ikon wanda hyperalgesia da puffness. Rage prostaglandins a cikin babban cibiyarzazzarune (galibi E1) yana haifar da haɓaka mai ɗumi, haɓaka ƙwayar ƙwayar jini ta fata kuma, a sakamakon haka, raguwar zafin jiki.
Ana samun sakamako mai narkewa ta hanyar yanki da kuma ayyukan tsakiyar magani. Asficore yana hana kira thromboxane A2 a cikin sel sel platelet, yana ragewa thrombosisadon platelet da nasu tarawa.
A cikin marasa lafiya da hanyar rashin daidaituwa na angina, sinadaran acetylsalicylic acid na iya rage mace-mace, haɗarin infarction myocardial.
Tasirin antiplatelet yana kusan mako guda bayan ɗaukar kashi ɗaya.
Yawan sha na yau da kullun na giram 6 ko fiye da haka yana ƙaruwa lokacin prothrombin, yana hana haɗin jiki prothrombin a cikin hanta hanta.
Maganin Aspicore yana ƙaruwa da yawan rikitarwa na basur yayin ayyukan tiyata.
A ƙarƙashin tasirin miyagun ƙwayoyi, an inganta haɓakar sha'awa uric acid (sakamakon cin amanar tubular reabsorption a cikin kodan).
Alamu don amfani
An wajabta Aspicor don taimako ciwo mai raɗaɗi (siffofi masu laushi da matsakaici) na asali iri-iri: migraine, ciwon kai, myalgiaradicular ciwo karsasannkaarthralgia lumbago, neuralgia, ciwon hakori.
Ana amfani da maganin don cututtukan febrile a kan asalin cutar, cututtukan cututtukan kumburi.
Contraindications
Ba a tsara allunan Aspicor ba basur na maganin basur, tare da nau'in rashin haƙuri na acetylsalicylic acid, tare da asma na hanji, zubar jini daga narkewa, tare da lalata da jijiyoyin jiki na narkewa, tsarin kula da methotrexates, gestation of ciki (na farko, na uku da na uku), shayar da mama da yara har zuwa shekaru goma sha biyar.
Side effects
Allunan ƙwayar Aspicor na iya haifar da zawo, tashin zuciya, amsar rashin lafiyar jiki ta hanyar angioedema, fatar fata da karin ƙarfe.
A kan tushen magani, keta haddi a cikin aikin kodan da hanta na yiwuwa, ci gaba Raunin Reye (saurin samuwar hanta, gazawar hanta da encephalopathy), leukopenia, thrombocytopeniatsananin matsananciyar damuwa.
Zai iya kasancewa tare da jiyya na dogon lokaci hypocoagulationerosive da ulcerative rauni na narkewa kamar jijiyoyi, amai, amai, amai, tashin hankali na gani,Jakazub da jini, papillary necrosis, prezoal azotemia tare da hypercalcemia da hypercreatininemia, kumburi, ƙara alamun bayyanar zuciya, bugun jini na hanji, haɓaka enzymes hanta, nephrotic syndrome.
Aspicor, umarnin don amfani (Hanyar da sashi)
Ana ɗaukar allunan Aspicore a baki.
Tare da ciwo, cututtukan febrile ana shan maganin ta baka har zuwa gram 3 (maganin da aka bada shawarar shine grai 0.5-1 a rana) don allurai 3.
A matsayin wakili na analgesic da anti-mai kumburi, Aspicor an wajabta shi a cikin kwayar 325 mg.
Tsawon lokacin rashin lafiya bai kamata ya wuce fiye da makonni biyu ba.
Dole ne a narke nau'in mafi kyawun maganin a cikin ruwa na 100-200 ml. Singleaya daga cikin adadin ƙwayoyi shine 0.25-1 grams (sau 3-4 a rana).
Yawan abin sama da ya kamata
A cikin mummunan yanayi na yawan yawan zubar jini, hauhawar jini, hauhawar jini, coma, zazzabi, ketoacidosis, zuciya da gazawar numfashi mai yiwuwa ne.
Ana buƙatar asibiti na gaggawa, yin amfani da gawayi na aiki, lavage na ciki, diuresis, hemodialysis, da kuma maganin rashin lafiya.
Haɗa kai
Umarnin don amfani da Aspicore baya bada shawarar yin amfani da magani a lokaci guda tare da wakilai na maganin haila, valproic acid, kashiwa, wakilai na antiplatelet, thrombolytics,kai tsaye anticoagulants, heparin, sulfonamides, antihypertensive da uricosuric jami'ai, diuretics.
Hadarin cututtukan gastrointestinal yana ƙaruwa tare da jiyya ta lokaci guda tare da glucocorticosteroids da ethanol magunguna.
Aspikor yana da ikon ƙara yawan barbiturates, digoxin, gishiri na lithium a cikin plasma.
Rage haɗarin acetylsalicylic acid an rage shi yayin jiyya antacids.
Sakamakon bashin jini na Aspicore yana ƙaruwa tare da magani tare da kwayoyi na myelotoxic.
Umarni na musamman
Yin amfani da Aspikor azaman maganin hana kumburi yana iyakance saboda babban haɗarin haɓaka NSAIDs-gastropathy.
Tsawon lokacin rashin lafiya bai kamata ya wuce kwanaki 5 ba.
A halin yanzu, ba a ba da magunguna don rheumatic choreakamuwa da cuta mai ƙwayar cuta myocarditis, tare da cututtukan cututtukan fata na rheumatoid, kazalika da cututtukan fata na farji da cututtukan fata da cututtukan fata.
An bada shawarar aspicor don dakatar da kwanaki 5-7 kafin aikin da aka shirya.
Jiyya na dogon lokaci yana buƙatar saka idanu akan tilas na ƙididdigar jini, nazarin feces don jinin tsafi.
Magungunan zai iya bayarwa tasirin teratogenic.
Acetylsalicylic acid an kebe shi a cikin madara.
Wani magani na iya haifar da mummunan cutar gout.
Nau'i na saki, marufi da abun ciki Aspicor ®
Allunan da ke ciki mai launin allunan farin ko kusan farin launi, zagaye, biconvex, a sashin giciye - wani taro mai hade da farin ko kusan farin launi.
| Shafin 1 | |
| Acetylsalicylic acid | 100 MG |
Fitowa: celclosese microcrystalline, lactose monohydrate, sodium croscarmellose, colloidal silicon dioxide (aerosil), acid stearic.
Abun da ke ciki na murfin kayan shiga: methaclates acid-ethyl acrylate copolymer, propipylene glycol, macrogol 4000, titanium dioxide, talc.
10 inji mai kwakwalwa. - fakitin bakin (1) - fakitoci na kwali.
10 inji mai kwakwalwa. - fakitin bakin (2) - fakitoci na kwali.
10 inji mai kwakwalwa. - fakiti mai bakin ciki (3) - fakitoci na kwali.
10 inji mai kwakwalwa. - fakitin bakin (6) - fakitoci na kwali.
Guda 20. - fakitin bakin (1) - fakitoci na kwali.
Aikin magunguna
NSAIDs, wakilin antiplatelet. Hanyar aiwatar da acetylsalicylic acid an gina shi ne akan abubuwan da ba'a iya canzawa ba game da hana cyclooxygenase-1 (COX-1), sakamakon hakan akwai toshewar thromboxane A saiti na 2 da kuma taɓin haɗuwar haɗuwar platelet. An yi imanin cewa acetylsalicylic acid yana da wasu hanyoyin da za su iya magance haɗuwar platelet, wanda ke faɗaɗa girma a cikin cututtukan jijiyoyin jiki daban-daban.
Acetylsalicylic acid shima yana da anti-inflammatory, analgesic, antipyretic sakamako.
Pharmacokinetics
Bayan gudanar da baki, an tattara acetylsalicylic acid daga ƙananan ƙananan hanji. Ana ganin C max a cikin plasma a matsakaici tsawon awanni 3 bayan fitowar magani.
Acetylsalicylic acid yana ɗaukar kashi na metabolism a cikin hanta tare da samuwar metabolites marasa aiki.
Kodan ya cire ta, duk da ba canzawa da metabolites. T 1/2 acetylsalicylic acid shine kusan minti 15, don metabolites - kimanin 3 hours
Alamu Aspikor ®
- rigakafin raunin myocardial mai lalacewa a gaban abubuwan haɗari (alal misali, ciwon sukari, hauhawar jini, hauhawar jini, kiba, shan sigari, tsufa),
- rigakafin na tartsatsi myocardial infarction,
- m angina,
- rigakafin bugun jini (gami da cikin marassa lafiya da cututtukan cututtukan zuciya),,
- rigakafin hadarin narkar da cutar sankara,
- rigakafin thromboembolism bayan tiyata da kuma tashin zuciya na jijiyoyin jini (alal misali, jijiyoyin zuciya jijiyoyin bugun jini, carotid artery endarterectomy, arteriovenous shunting, carotid artery angioplasty),
- rigakafin zurfin jijiya mara nauyi da kuma thromboembolism na huhu da kuma rassanta (alal misali, tare da tsawan lokaci na hana haihuwa sakamakon babban aikin tiyata).
| Lambar ICD-10 | Nuna |
| G45 | An kawo harin hare-hare na haihuwar jijiyoyin kai tsaye da kuma abubuwanda suka danganci juna |
| I20.0 | Angina mai tsauri |
| I21 | Babban myocardial infarction |
| I26 | Kwayar cutar sankara a cikin ƙwayar cuta |
| I61 | Cutar ciki na ciki (nau'in basur na nakasar ciki) |
| I63 | Cerbral infarction |
| I74 | Embolism da jijiya jini |
| I82 | Embolism da thrombosis na sauran jijiya |
Sakawa lokacin
Allunan ya kamata a ɗauka a baka, kafin abinci, tare da yalwa da ruwaye.
Yin rigakafin cutar myocardial da ake zargi da lalacewa: 100-200 mg / rana (dole ne a kirkiri kwamfutar hannu ta farko don ɗaukar sauri).
Yin rigakafin mummunan myocardial infarction a gaban abubuwan haɗari: 100 MG / rana.
Yin rigakafin infarction na myocardial na ta dawowa, angina mai tsayayye, rigakafin bugun jini da hadarin cerebrovascular, hana rigakafin thromboembolic bayan tiyata ko karatu mai ban mama: 100-300 mg / day.
Yin rigakafin thrombosis mai zurfi da thromboembolism na huhu da kuma rassansa: 100-200 mg / rana.
An yi nufin amfani da miyagun ƙwayoyi don tsawan amfani. Tsawan likitan ne zai tantance tsawon lokacin da likitan yake.
Side sakamako
Daga tsarin narkewa: tashin zuciya, ƙwannafi, amai, jin zafi a cikin ciki, raunuka na ƙwayar ciki na ciki da duodenum (ciki har da lalacewa), zubar jini na hanji, ƙara yawan aiki na hanta enzymes.
Daga tsarin numfashi: bronchospasm.
Daga tsarin hawan jini: karuwar zubar jini, da wuya - anemia.
Daga gefen tsarin juyayi na tsakiya: dizziness, tinnitus.
Allergic halayen: urticaria, Quincke ta edema, anaphylactic halayen.
Haihuwa da lactation
Amfani da salicylates a cikin allurai masu girma cikin farkon farkon haihuwa yana da alaƙa da haɓakar kumburin haɓakar tayi (raunin ƙasa, raunin zuciya). A cikin watanni biyu na ciki, ana iya ba da umarnin yin amfani da sutturar salula tare da cikakken ƙima na hadarin da fa'ida.
A cikin kashi uku na ciki na ciki, salicylates a cikin allurai masu yawa (fiye da 300 mg / rana) suna haifar da hanawar aiki, rufewar hanji da yatsun mahaifa a cikin tayin, ƙara yawan zubar jini a cikin mahaifiya da tayin, da kuma kulawa kai tsaye kafin haihuwa na iya haifar da zubar jini cikin mahaifa, musamman a cikin jarirai. Nadin salicylates a cikin uku na ciki na ciki ya haɗu.
Salicylates da metabolites dinsu a cikin adadi kaɗan an keɓance su cikin madara. Yawan cin abinci mai gishiri a lokacin shayarwa baya tare da haɓakar halayen da ake samu a cikin yaran kuma baya buƙatar daina shayarwa. Koyaya, idan kuna buƙatar amfani da magani na dogon lokaci ko alƙawarin babban kashi, ya kamata a dakatar da shayar da jarirai nan da nan.
Hulɗa da ƙwayoyi
Ta amfani da acetylsalicylic acid na lokaci daya yana haɓaka aikin waɗannan kwayoyi masu zuwa:
- methotrexate ta hanyar rage keɓaɓɓen izini da kuma kawar dashi daga sadarwa tare da sunadarai,
- heparin da magungunan anticoagulants a kaikaice saboda aikin platelet mai rauni da kuma kawar da maganin rashin daidaituwa ta hanyar sadarwa tare da sunadarai,
- magungunan thrombolytic da antiplatelet (ticlopidine),
- digoxin saboda raguwa a cikin keɓaɓɓen hatsi,
- hypoglycemic jamiái (insulin da abubuwan da ake samowa na sulfonylurea) saboda abubuwan hypoglycemic na acetylsalicylic acid da kansa a cikin allurai masu yawa da kuma kwararar abubuwan da suka samo asali na sulfonylurea daga sadarwa tare da sunadarai,
- valproic acid saboda taɓarɓarewa daga sadarwa tare da sunadarai.
Ana lura da sakamako mai ƙari yayin ɗaukar acetylsalicylic acid tare da ethanol.
Acetylsalicylic acid yana raunana sakamako na kwayoyi uricosuric (benzbromarone) saboda gushewar tubular gasa ta uric acid.
Ta hanyar inganta kawar da salicylates, tsarin corticosteroids na rushe tasirin su.
VERTEX AO (Russia)
199106 St. Petersburg Aspikard (BORISOVA SIFFOFIN Cutar Magunguna, Jamhuriyar Belarus) Aspinat ® (VALENTA PHARMACEUTICS, Rasha) Aspinat ® Cardio (VALENTA PHARMACEUTICS, Rasha) Asfirin ® Cardio (BAYER CONSUMER CARE, Switzerland) Acetylcardio-LekT (TYUMEN CHEMICAL - PHARMACEUTICAL Plan, Russia) Formaddamar da tsari da abun da ke cikiAspicore ana samarwa a cikin nau'ikan allunan da ke ciki mai launi: kusan fararen fari ko fari, biconvex, zagaye, a sashin giciye - taro mai hade da kusan farin ko fari (guda 10 a cikin boro, a cikin wani kwali na 1, 2, 3 ko Fakitoci 6, guda 15 kowannensu a cikin fakitoci, a cikin fakitin fakiti 2 ko 4, fakitoci 20 cikin fakitoci, a cikin kwali 1 ko 3 fakitoci, guda 30 a cikin kwalba ) Abun ciki 1 kwamfutar hannu:
Sashi da gudanarwaAna ɗaukar Aspikor a baki, kafin abinci, allunan ya kamata a wanke su da yawan ruwaye. Magungunan an yi niyya don amfani na dogon lokaci, an saita hanya daban ta likitan halartar. A cikin lura da angina mai tsayayye, Aspicor suna amfani da allunan 1-3 (100-300 mg) kowace rana. Don hana kwayar cutar ana bada shawarar a sha a allurai na yau da kullun:
Aspicore, umarnin don amfani: hanyar da sashiDole ne a sha allunan Aspicore a baki kafin abinci, tare da yalwar ruwa. Nagari allurai na yau da kullun:
Aspikor an yi niyya ne don maganin warkewa, na tsawon lokacin da likitan halartar ya ƙaddara. Haihuwa da lactation
Aspicore: farashin a cikin kantin magani na kan layiAspicore 100 MG allunan da aka saka allunan 30 inji mai kwakwalwa. ASPICOR 100mg 30 inji mai kwakwalwa. allunan mai kauri Tabdigar Aspicor. .p / o fim. dabaru. 100mg n30 ASPICOR 100mg 90 inji mai kwakwalwa. allunan mai kauri Tabdigar Aspicor. n / a ksh / Sol. 100mg No. 90 Aspicore 100 MG Allunan kwakwalwan kwamfuta mai kwakwalwa 90 inji mai kwakwalwa.
Ilimi: Na farko Jami'ar Likita ta Jihar Moscow da aka sanya wa lakabi da I.M. Sechenov, ƙwararren "General Medicine". Bayanai game da miyagun ƙwayoyi an samar da su, an bayar da su ne don dalilai na bayanai kuma baya maye gurbin umarnin hukuma. Kai magani yana da haɗari ga lafiya! Aikin da mutum baya so yafi cutarwa ga kwakwalwarsa fiye da rashin aiki kwata-kwata. Dangane da bincike, matan da ke shan tabarau na giya ko giya a mako guda suna da haɗarin kamuwa da cutar sankarar mama. Wani dan Australiya mai shekaru 74 James Harrison ya zama mai bayar da gudummawar jini kusan sau 1,000. Yana da nau'in jini wanda ba a taɓa gani ba, rigakafin cututtukan rigakafi waɗanda ke taimaka wa jarirai masu ƙarancin rashin wadatar rayuwa. Don haka, Ostiraliya ta sami kusan yara miliyan biyu. A cewar masana kimiyya da yawa, hadadden bitamin ba su da amfani ga mutane. Yayin sneeze, jikinmu gaba ɗaya yana dakatar da aiki. Har zuciyar ta tsaya. A lokacin rayuwa, matsakaicin mutum ya samar da kasa da ruwa biyu na yau. Ya kasance hakan yana haɓaka jiki da oxygen. Koyaya, wannan ra'ayi ya gurbata. Masana ilimin kimiyya sun tabbatar da cewa hayaniya, mutum yana sanya kwantar da hankali da haɓaka aikinsa. Yayin aiki, kwakwalwarmu tana amfani da adadin kuzari daidai da wutar fitila 10-watt. Don haka hoton gilashin haske sama da kanka a lokacin bayyanar tunani mai ban sha'awa ba ya da nisa da gaskiya. Idan kun fada daga jaki, ya fi dacewa ku mirgine wuyanku fiye da idan kuka faɗo daga dawakai. Kawai kada kuyi kokarin musun wannan magana. A yunƙurin fitar da mara lafiya, likitoci sukan yi nisa sosai. Don haka, alal misali, wani Charles Jensen a cikin shekarun daga 1954 zuwa 1994. ya tsira fiye da 900 aikin cirewar neoplasm. Mutumin da ke shan magungunan maye a yawancin lokuta zai sake fuskantar wahala daga bacin rai. Idan mutum ya jimre da damuwa na kashin kansa, yana da kowane damar ya manta da wannan halin har abada. Ko da zuciyar mutum ba ta doke ba, to zai iya rayuwa na tsawon lokaci, kamar yadda masanin kifin nan na ƙasar Jan Revsdal ya nuna mana. “Motar” sa ya tsaya na tsawon awanni 4 bayan masun ɗin ya ɓace kuma ya faɗi cikin dusar ƙanƙara. Magunguna da yawa an fara tallata su azaman magunguna. Misali, a farko, an siyar da Heroin azaman maganin tari. Kuma likitoci sun ba da shawarar yin amfani da cocaine a matsayin maganin hana haihuwa da kuma hanyar wadatar da haƙuri. An rubuta mafi yawan zafin jiki na jiki a Willie Jones (Amurka), wanda aka shigar da shi asibiti tare da zazzabi na 46.5 ° C. Cutar hanta ita ce mafi girman jikinmu. Matsakaicin nauyinta shine kilogiram 1.5. An san man kifi na shekaru da yawa, kuma a wannan lokacin an tabbatar da cewa yana taimakawa wajen rage kumburi, yana kawar da ciwon haɗin gwiwa, inganta haɓaka.
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