Vipidia 25 MG

Vipidia (Allunan) Rating: 177

Mai masana'anta: Ana yin karin bayani
Siffofin Saki:

• Tab. 12.5 mg, 28 inji mai kwakwalwa,, Farashin daga 973 rubles
• Tab. 25 mg, 28 inji mai kwakwalwa., Farashin daga 1282 rubles

Farashin Vipidia a cikin kantin magani na kan layi
Umarnin don amfani

Vipidia shine wakili na hypoglycemic a cikin allunan tare da alogliptin. Yana ba da raguwa a cikin glycosylated haemoglobin da glucose. An nuna shi idan akwai nau'in ciwon sukari na 2 na mellitus a cikin hanyar monotherapy, kazalika a haɗuwa da jiyya tare da sauran wakilai na hypoglycemic. Mafi kyawun sashi shine 25 mg / rana, ana ɗauka komai abinci. Contraindicated a cikin ciwon sukari ketoacidosis, type 1 ciwon sukari mellitus, mai tsanani mai rauni zuciya, na koda da gazawar hanta. Abubuwan da ke tattare da cutarwa na iya haɗawa da ciwon kai, tashin hankali a cikin hanji, fitsari, cututtukan cututtuka na gabobin ENT. Ba a ba da umarnin ƙananan yara 'yan ƙasa da shekara 18 da mata masu juna biyu saboda rashin bayanai game da aikace-aikacen.

Analogs na miyagun ƙwayoyi Vipidia

Analog ne mai rahusa daga 863 rubles.

Mai masana'anta: Merck Sante SAA.S. (Faransa)
Siffofin Saki:

• Allunan 500 MG, 30 inji mai kwakwalwa., Farashin daga 110 rubles
• Allunan 1000 MG, 30 inji mai kwakwalwa., Farashin daga 185 rubles

Farashin Glucophage a cikin magunguna kan layi
Umarnin don amfani

Magungunan Faransa don maganin cututtukan type 2. Sanarwa a cikin allunan da ke kunshe daga 500 zuwa 1000 MG na metformin azaman kayan maye mai aiki. Akwai contraindications, sabili da haka, kafin ɗaukar Glucofage, ya zama dole a nemi shawara tare da gwani.

Analog mai rahusa daga 182 rubles.

Mai masana'anta: Novartis (Switzerland)
Siffofin Saki:

• Allunan 50 MG, pcs 28., Farashin daga 791 rubles
• Allunan 1000 MG, 30 inji mai kwakwalwa., Farashin daga 185 rubles

Farashin Galvus a cikin kantin magani na kan layi
Umarnin don amfani

Galvus shiri ne na kwamfutar hannu don maganin nau'in mellitus na ciwon sukari na 2 dangane da vildagliptin a cikin sashi na 50 MG. Ana iya tsara shi duka biyu azaman maganin tauhidi kuma a matsayin ɓangaren haɗin magani idan akwai rashin ingancin abinci da motsa jiki.

Analog mai rahusa daga 795 rubles.

Mai masana'anta: Hemofarm A.D. (Serbia)
Siffofin Saki:

• Tab. 500 MG, pcs 60., Farashin daga 178 rubles
• Allunan 1000 MG, 30 inji mai kwakwalwa., Farashin daga 185 rubles

Farashin Metformin a cikin kantin magani na kan layi
Umarnin don amfani

Metformin magani ne na Serbian hypoglycemic don amfani na ciki. Abun da ke tattare da Allunan yana dauke da sinadaran aiki mai suna iri ɗaya a cikin adadin 500 ko 850 MG. An wajabta don maganin cututtukan type 2 (a cikin manya), musamman ma a cikin lokuta masu kiba.

Analog ya fi tsada daga 799 rubles.

Mai masana'anta: Bristol Myers Squibb (Amurka)
Siffofin Saki:

• Allunan 5 MG, pc 30., Farashin daga 1772 rubles
• Allunan 1000 MG, 30 inji mai kwakwalwa., Farashin daga 185 rubles

Farashi don Onglisa a cikin kantin magani na kan layi
Umarnin don amfani

Onglisa magani ne na Amurka don magance nau'in ciwon sukari na 2 na sukari dangane da saxagliptin a cikin sashi na 2.5 ko 5 mg. An wajabta shi ban da aikin jiki da rage cin abinci don inganta sarrafa glycemic.

Analog ya fi tsada daga 1236 rubles.

Mai masana'anta: Merck Sharp and Dome (Amurka)
Siffofin Saki:

• Allunan 100 MG, guda biyu., Farashin daga 2209 rubles
• Allunan 1000 MG, 30 inji mai kwakwalwa., Farashin daga 185 rubles

Farashin kuɗi don Januvia a cikin kantin magani na kan layi
Umarnin don amfani

Januvia magani ne na Americanan asalin Amurka don ciwon sukari. Sinadaran aiki: sitagliptin (a cikin nau'in phosphate monohydrate) 100 MG. Ana iya amfani dashi azaman ƙari ga aikin jiki da abinci don sarrafa sukari na jini.

Analog ya fi tsada daga 675 rubles.

Mai masana'anta: Beringer Ingelheim (Austria)
Siffofin Saki:

• Allunan 5 MG, pc 30., Farashin daga 1648 rubles
• Allunan 1000 MG, 30 inji mai kwakwalwa., Farashin daga 185 rubles

Farashi don Trazhenta a cikin kantin magani na kan layi
Umarnin don amfani

Trazhenta - wani magungunan Ostaraliya da aka yi niyya don magance cututtukan ciwon sukari na 2, ana iya sa shi duka biyu a matsayin maganin- kuma a matsayin ɓangaren haɗin maganin. Abinda ke aiki kawai a cikin abun da ke ciki shine linagliptin a cikin sashi na 5 MG. Ba a wajabta Trazenta don kamuwa da cututtukan type 1 ba, a lokacin daukar ciki, lactation, da kuma a cikin yara 'yan ƙasa da shekaru 18.

Tsarin saki, abun da aka shirya da shiryashi

Magungunan an yi shi ne da nau'in allunan kwalaji mai rufi tare da membrane fim. Sashi:

• 12.5 MG - Allunan launin rawaya
• 25 MG - wani ɗan kwalliyar ja.

Ana sayar da samfurin a cikin fakitin kwali. Shiryawa: blister 4, mai dauke da allunan 7, jimlar 28 a cikin fakitin.

Abubuwan da ke aiki na miyagun ƙwayoyi shine alogliptin. Karin abubuwa:

• magnesium stearate,
• croscarmellose sodium
• microcrystalline cellulose,
• Hyprolose

Filin fim na kwamfutar hannu ya ƙunshi:

• sabbinne,
• baƙin ƙarfe oxide
• titanium dioxide
• macrogol
• launin toka mai launin F1

Ayyukan magunguna

Alogliptin wani inhibitor ne mai zaɓin dipeptidyl peptidase-4 sosai. DPP-4 shine babban enzyme wanda ke haifar da saurin lalacewar kwayoyin halittun da ke cikin iyali. Musamman, shi ne polypeptide insulinotropic polypeptide (HIP) da glucagon-kamar peptide-1 (GLP-1). Ana samar da wadannan kwayoyin halittar a cikin hanji, kuma matakin su ya bambanta da abincin da aka ci. Sakamakon HIP da GLP-1 an yi niyya don kunna ayyukan insulin kai tsaye a cikin ƙwayar cuta.

Peptide mai kama da Glucagon yana taimakawa rage yawan glucagon da rage jinkirin samar da glucose a cikin hanta. Tare da kowane canje-canje a cikin matakin incretins a ƙarƙashin rinjayar alogliptin, haɓakar insulin yana ƙaruwa kuma glucagon yana raguwa tare da ƙara yawan sukari. A cikin mutane masu ciwon sukari, irin waɗannan canje-canjen suna haifar da daidaituwa na gemocosylated haemoglobin da sauran ma'aunin jini kafin da bayan abinci.

Pharmacokinetics

Magungunan daidai suna shafar lafiyar mutum da haƙuri tare da ciwon sukari. Alogliptin yana cikin jiki kusan kashi 100%, komai girman abincin da aka cinye. Tare da kwamfutar hannu guda ɗaya, abu mai aiki yana ɗaukar hanzari cikin jini, inda bayan awa 1 zuwa 2 ana samun yawan ƙwayar magunguna.

Alogliptin yana da kyau a rarraba shi da kyau a kyallen takarda. Dangantaka da sunadaran plasma kusan 20-30%. Tare da tsawanta yin amfani da miyagun ƙwayoyi, tarin abu mai aiki a cikin jikin mutum, bisa ga bayanan asibiti, ba a lura da lafiya ko marasa lafiya ba. A tsakanin awanni 21 bayan shan maganin, kashi 70% na kayan yana cire ta ta hanyar da ba'a canza shi ba, 13% ta hanji.

Anyi maganin Vipidia don ciwon sukari na 2. Kayan aiki yana taimaka wa marasa lafiya yadda ya kamata, har ma da rashin bin ka'idodin abinci da rashin mahimmancin aikin jiki. Za'a iya amfani da maganin a matsayin monotherapy. Kuna iya sha shi tare da sauran magunguna waɗanda ke taimakawa rage yawan sukari a cikin jini.

Contraindications

Kamar kowane magani, Vipidia yana da iyaka. Karanta su a hankali.

Kada a bugu da miyagun ƙwayoyi tare da:

• hypersensitivity na jiki ga kowane abu da ke cikin miyagun ƙwayoyi,
• nau'in ciwon sukari guda 1
• mai ciwon sukari ketoacidosis,
• na kullum zuciya
• lalacewar hanta,
• ciki da lactation,
• yara ‘yan kasa da shekara 18.

Tare da taka tsantsan lokacin da:

• maganin cututtukan farji
• matsakaici na koda

Umarnin don amfani (sashi)

Ya kamata a sha Vipidia a baki, duka kafin kuma bayan abinci. An ba da shawarar yin amfani da ba fiye da 25 MG kowace rana. Wani lokaci ana tsara shi tare da wasu kwayoyi, kamar:

Tare da aikin haɗin gwiwa na Vipidia tare da metformin ko thiazolidinedione, kashi ɗin ya kasance canzawa. Don ware haɗarin hypoglycemia, lokacin da aka tsara maganin a lokaci guda tare da insulin, ya zama dole don rage sashi na ƙarshen. Idan saboda wasu dalilai kun manta shan shan maganin, kuna buƙatar gyara shi da sauri. Amma a lokaci guda kar a sha kashi biyu.

Matsayin glucose a cikin jini kai tsaye ya dogara da abun da ke cikin alogliptin a cikin jiki. Sabili da haka, ba a ba da shawarar yin amfani da magani ba.

Side effects

Akwai wasu lokuta idan alamun rashin tausayi suka faru saboda maganin Vipidia. Mai haƙuri na iya yin gunaguni na:

• ciwon kai
• kamuwa da cutar huhu
• nasopharyngitis,
• zafi a ciki
• itching da fata tayi,
• cin gaban pancreatitis,
• da samuwar na koda gazawa.

Idan an gano irin waɗannan alamun tashin hankali, ya kamata ka sanar da likitanka. Zai iya yanke shawara don ci gaba da magani tare da miyagun ƙwayoyi ko a'a. Bayyananniyar bayyanar alamun alamun da ke sama na buƙatar cire maganin a cikin gaggawa.

Yawan abin sama da ya kamata

Yawan wuce haddi ba ya haifar da wata barazana ga mutane. Ana buƙatar taimakon likita ne kawai a lokuta idan ya kasance mai haƙuri ga Vipidia ko lokacin shan magunguna ta hanyar mutanen da ke fama da cututtukan da ke cikin jerin cututtukan contraindications. Taimako na farko don yawan abin sama da ya kamata - lavage na ciki.

Umarni na musamman

Amfani da jituwa na Vipidia tare da insulin da wasu magunguna waɗanda ke rage sukari jini yana buƙatar daidaita sashi don hana ci gaban hauhawar jini. Dangane da bincike na asibiti, hulɗa da alogliptin tare da wasu na'urorin likitanci bai nuna canje-canjen da aka ambata ba.

Alogliptin yana shafar jikin sosai, saboda haka yayin jiyya ya kamata ka ƙi shan giya.

Magungunan "Vipidia" ba ya haifar da nutsuwa, don haka tuki da sauran ayyukan da ke buƙatar karuwar hankalin ne da yawa ba a haramta su ba.

Mahimmanci: binciken ya nuna cewa magani ba ya tasiri sosai a hanta, a ɗan karya ayyukansa. Har zuwa lokacin da muni zai iya faruwa. Sabili da haka, kafin amfani da maganin, ya zama dole a sami cikakken jarrabawa tare da kwatanta duk ribobi da mazan jiya.

Sakamakon karancin bayani game da mummunan yanayin yayin ciki da lactation, ya fi kyau kar a sha Vipidia.

Yara da tsufa

Bayar da magunguna ga yara da matasa masu shekaru 18 da suka wuce, yana sanadin rikice-rikice, saboda karancin bayanan asibiti a wannan zamani.

Marasa lafiya waɗanda shekarunsu suka wuce 60 na iya shan "Vipidiya". Ba a buƙatar amfani da maganin da aka saba koyaushe. Koyaya, yakamata a ɗauka a cikin zuciya cewa yiwuwar raguwar aikin kodan da hanta ya dogara da ƙayyadadden adadin ƙwayoyin cuta.

Sharuɗɗan da yanayin ajiya

Cire magani a cikin duhu, wuri mai sanyi daga yara. Maganar amfani shekaru uku ne daga ranar fitowa. Ranar da aka keɓance ranar haɗaɗɗiyar kayan aikin. An haramta amfani da miyagun ƙwayoyi.

Farashin Vipidia a cikin kantin magunguna ya bambanta da yawan magunguna da yankin zama. Matsakaicin, yana 845 - 1390 rubles.

Ba a sayar da magani ba, ana iya siye shi kawai ta hanyar takardar sayan magani.

Kwatanta tare da analogues

Idan saboda wasu dalilai magani bai dace da mai haƙuri ba, likita yana neman magani wanda za'a iya maye gurbinsa.

Jerin likitocin maganin "Vipidia":

Suna	Amfanin
Karin Galvus	Hanya mai tasiri don rage matakan sukari. Hakanan yana taimakawa kawar da karin fam ba tare da tilasta abinci ba.	Babban jerin tasirin sakamako masu illa. Babban farashin magunguna.	Daga 780 rubles.
Alogliptin	Yana taimakawa daidaitaccen matakan glucose. Ba ya haifar da haɓaka metabolism. Ba ya tara, gabaɗaya daga jikin.	Ba za a iya amfani da shi ba don cututtukan ƙwayoyin cuta na hanta, hanta, cututtukan fata. Magungunan ba su da arha.	Daga 845 rubles.
Januvia	Yana inganta rage nauyi, rage cin abinci, yana daidaita sigogin jini.	Kudinsa. Yana da magungunan contraindications da yawa don amfani, don haka yana da mahimmanci cewa likita ya wajabta maganin.	Daga 1350 rubles

Yawancin martani daga masu ciwon sukari da ke shan Vipidia suna da kyau. Waɗannan allunan yadda yakamata suna rage glucose jini, ana haƙuri da kyau, amma yakamata a yi amfani da shi kamar yadda likitan ya umurce shi. Mutane ba sa son gaskiyar cewa maganin yana da tsada. Ga wasu dubai na hakika:

Na kamu da ciwon sukari shekaru 5 da suka gabata. An yi mata rajista tare da likitancin endocrinologist, ta sha kwayoyi da yawa. Amma 'yan makonnin da suka gabata, sukari ya fara tashi zuwa raka'a 18. Likita ya rubuta mani Vipidia. Na dauki kwamfutar hannu guda ɗaya kawai a rana, sukari daidai ne. Ina murna sosai. Ni da kaina na samu a cikin wannan maganin amfani guda ɗaya.

Vipidia yana maye gurbin insulin sosai. Kuma a kwatanta shi, maganin kawai yana buƙatar ɗauka sau ɗaya a rana. Ba lallai ba ne don adana abinci. Ina da ciwon sukari, allunan suna daidaita matakin glucose a cikin jini, don haka na riga na ƙi insulin na dogon lokaci. Gaskiya abun rikicewa ne game da farashin, magani ba shi da arha, ba kowa ne zai iya wadatar ba. Amma, ba shakka, akwai ƙari. Ina ba da shawarar shi ga kowa da kowa.

Ina da ciwon sukari na 2 Anyi mata magani, ta sha kwayoyi kullum, amma sai glucose din ya ragu, sannan kuma ya kara zuwa raka'a 12. Akwai lokuta na maganganu na hypoglycemic, raguwa mai ƙarfi na sukari. Likita ya rubuta mani Vipidia. Na yi farin ciki da miyagun ƙwayoyi. Ina shan kwamfutar hannu guda kawai da safe kuma komai na al'ada. Kodayake yana da tsada, amma ban lura da sauyawa a cikin sigogi na jini ba kuma kwantar da hankalin kullun. Ina ba da shawarar shi ga kowa da kowa.

Likita ya ba ni takardar sayen magani don siyan maganin "Vipidia". Na kamu da ciwon sukari tsawon shekaru. Ina son maganin, yana rage alamomin glucose da kyau. Ina sha sau ɗaya kawai a rana. Ba shi da contraindications lokacin hulɗa tare da wasu magunguna, wanda yake da kyau musamman. Ba ya cutar da kwakwalwa kuma baya haifar da nutsuwa. Ba a hana hawa mota tare da shi ba. Na gamsu da komai, ingantaccen magani wanda bai haifar min da wata illa ba.

Saki siffofin da abun da ke ciki

Ana yin maganin ne a cikin kwamfutar hannu wanda ke dauke da nauyin 25 na kayan aiki - alogliptin benzoate. Tushen allunan an cika shi ta hanyar abubuwan taimako:

• microcrystalline cellulose,
• magnesium stearate,
• mannitol
• makarin sodium,
• hauhawar jini.

Fuska a jikin allunan, membrane fim ne wanda yake kunshe da hypromellose, titanium dioxide, macrogol 8000, fenti mai haske dangane da sinadarin iron. Allunan 25m sune hasken wuta mai haske.

Aikin magunguna

Magungunan yana cikin rukunan hypoglycemic jami'ai saboda zaɓin maye na ayyukan dipeptidyl peptidase-4. DPP-4 babban enzyme ne wanda ke da hannu a cikin lalacewar haɓakar ƙwayoyin abubuwan haɓaka na ciki - enteroglucagon da peptide insulinotropic, wanda ya dogara da matakin glucose (HIP).

Hormones daga ɓangaren incretins ana samarwa a cikin hanji. Concentarfafa taro na sinadarai yana ƙaruwa tare da ɗimbin abinci. Glucagon-kamar peptide da GUI suna haɓaka aikin insulin a cikin tsibirin na pancreatic na Langerhans. Enteroglucagon lokaci guda yana hana haɗin glucagon kuma yana hana gluconeogenesis a cikin hepatocytes, wanda ke ƙara yawan ƙwayar plasma na incretins. Alogliptin yana ƙara ɓoye insulin, dangane da sukarin jini.

Alamu don amfani

An wajabta magunguna ga marasa lafiya don lura da nau'in ciwon sukari marasa ƙarfi na insulin 2 na ciwon sukari da kuma daidaituwa na sarrafa glycemic a kan tushen ƙarancin maganin cutar abinci da aiki na jiki. Ga marasa lafiya da suka manyanta, ana iya ba da maganin kamar yadda monotherapy, kuma a matsayin wani ɓangare na wani hadadden magani tare da Insulin ko wasu magunguna na hypoglycemic.

Yadda ake ɗaukar Vipidia 25?

Allunan an yi niyya don amfani da baka. An ba da shawarar yin amfani da miyagun ƙwayoyi tare da sashi na 25 MG sau ɗaya a rana, ba tare da la'akari da abincin ba. Rukunin magungunan ba za a iya tauna ba, saboda lalacewar injiniyan yana rage ƙimar yawan shan alogliptin a cikin ƙananan hanjin. Kada ku ɗauki kashi biyu.Mara lafiyar da ya rasa kwaya don kowane dalili ya kamata ya karba da wuri-wuri.

Ciwon sukari

Masana ilimin abinci sun bada shawarar shan Allunan Vipidia bayan abinci lokacin da matakan sukari na jini suka tashi. Lokacin ƙirƙirar magani azaman ƙarin kayan aiki don maganin tare da Metmorphine ko Thiazolidinedione, babu buƙatar daidaita tsarin sashi na ƙarshen.

Tare da gudanar da abubuwa masu daidaituwa na abubuwan da suka samo asali na sulfonylurea, ana rage adadin su don hana ci gaban jihar ta hypoglycemic. Sakamakon yiwuwar haɗarin hypoglycemia, ya zama dole don sarrafa matakin sukari yayin jiyya tare da Metformin, hormone pancreatic da Thiazolidinedione tare da Vipidia.

Sakamakon yiwuwar haɗarin hypoglycemia, ya wajaba don sarrafa matakin sukari yayin maganin Metformin.

Rashin Tsarin Tsarin na rigakafi

A kan asalin rauni na rigakafi, raunin da ke tattare da cutar na huhu da haɓakar nasopharyngitis yana yiwuwa.

A ɓangaren fata

Sakamakon zafin nama, ƙyallen fata ko ƙaiƙayi na iya bayyana. A bangaren tunani, bayyanar cututtukan Stevens-Johnson, urticaria, cututtukan fata na fata.

A cikin marasa lafiya sun yanke shawarar bayyanar halayen anaphylactoid, maganin urticaria, ana lura da edema Quincke. A cikin lokuta masu wahala, tashin hankali anaphylactic ya haɗu.

Yi amfani da lokacin daukar ciki da lactation

Ba a gudanar da karatun asibiti game da tasirin magani a jikin mata lokacin daukar ciki ba. Yayin aiwatar da gwaje-gwajen kan dabbobi, babu wani mummunan sakamako na miyagun ƙwayoyi akan gabobin tsarin haihuwa, mahaifar tayi, ko teratogenicity na Vipidia. A lokaci guda, don dalilai na aminci, ba a ba da magunguna ga mata yayin daukar ciki (saboda yuwuwar yiwuwar keta haddin gabobin da tsarin tsarin aiwatarwar tayi).

Alogliptin yana da ikon buɗewa ta cikin gland mai shayarwa, sabili da haka, a lokacin da ake amfani da maganin ƙwayar cuta, ana bada shawara don barin lactation.

Aikace-aikacen aiki mara kyau

A gaban rauni na koda a cikin haɓakar ƙarancin halittar kere kere (Cl) daga 50 zuwa 70 ml / min, ba a yin ƙarin canje-canje ga tsarin allurai. Tare da Cl daga 29 zuwa 49 ml / min, ya zama dole don rage ƙa'idodin yau da kullun zuwa 12.5 MG don kashi ɗaya.

A gaban rauni na koda a cikin haɓakar ƙarancin halittar kere kere (Cl) daga 50 zuwa 70 ml / min, ba a yin ƙarin canje-canje ga tsarin allurai.

Tare da lalata daskararction na koda (Cl ya kai ƙasa da 29 ml / min), an haramta shan miyagun ƙwayoyi.

Yin hulɗa tare da wasu kwayoyi

Magungunan ba su da hulɗa tare da magunguna tare da gudanar da sabis na Vipidia na lokaci daya tare da wasu magunguna. Magungunan ba su hana ayyukan cytochrome isoenzymes P450, monooxygenase 2C9. Ba ya hulɗa tare da abubuwan da ake kira p-glycoprotein. Alogliptin a cikin karatun karatun magunguna bai shafi canje-canje a matakin maganin kafeyin, Warfarin, Dextromethorphan, maganin hana haihuwa a cikin plasma.

Magungunan ba ya shafar canje-canje a matakin Dextromethorphan a cikin jiki.

Abun dacewa

A lokacin jiyya tare da maganin, haramun ne a sha giya. Ethanol da ke cikin giya na iya haifar da gurbatar mai a hanta sakamakon cutarwa mai guba kan hepatocytes. Lokacin shan Vipidia, ana inganta sakamako mai guba a kan tsarin hepatobiliary. Ethyl barasa yana haifar da hana tsarin juyayi na tsakiya, yana hana jini zagayawa kuma yana da sakamako mai diuretic. Sakamakon sakamakon barasa a jikin mutum, an rage tasirin warkewar magunguna.

Abubuwa na miyagun ƙwayoyi waɗanda ke da irin kayan kidayar magunguna da tsarin sunadarai na kayan aiki sun haɗa da:

Likita mai halarta yana zaban likitan halartar ne gwargwadon alamu na maida hankali kan sukari jini da kuma yanayin mai haƙuri. Sauyawa ana aiwatar da shi ne kawai in babu maganin warkewa ko kuma a sahun wasu halayen da aka ambata.

Alamu da contraindications don amfani

Vipidia magani ne na baka. Ana amfani da wannan kayan aikin don maganin ciwon sukari na 2. Wannan magani mai ciwon sukari yana taimakawa haɓaka ikon kula da glycemia a cikin ƙwayar jini na mara lafiya. Ana amfani da magani lokacin da ake amfani da maganin rage cin abinci da kuma motsa jiki a cikin jiki ba ya ba da sakamakon da ake so.

Za'a iya amfani da miyagun ƙwayoyi azaman sashin kawai yayin monotherapy. Bugu da kari, za a iya amfani da Vipidia a hade tare da sauran magunguna na hypoglycemic a cikin lura da nau'in ciwon sukari na 2 na mellitus ta hanyar hadadden maganin.

Za'a iya amfani da maganin a cikin maganin cututtukan sukari a hade tare da insulin.

Kamar kowane magani, Vipidia yana da contraindications da yawa waɗanda ke iyakance amfani da miyagun ƙwayoyi. Babban contraindications kamar haka:

• kasancewar nau'in ciwon sukari na 2 a cikin mara haƙuri, rashin jituwa ga kayan aikin da keɓaɓɓe da magunguna,
• haƙuri yana da ciwon sukari a cikin wani tsari-dogara da insulin,
• gano alamun ketoacidosis yana haɓaka a jikin mai haƙuri dangane da tushen ciwon sukari,
• gano mai rauni na zuciya,
• rikice-rikice a cikin hanta, wanda ke haɗuwa tare da abin da ya faru na rashin aiki,
• ci gaba da mummunan koda na cututtukan koda, wanda ke hade da abin da ya faru na rashin aiki,
• lokacin haihuwar yaro,
• lactation zamani
• Shekarun mai haƙuri har zuwa shekaru 18.

Ya kamata a lura da hankali lokacin da mai haƙuri ya kamu da ciwon ƙwayar ƙwayar cutar ƙwayar cuta da kuma matsakaicin matsayi na rashin aiki a cikin aiki na ƙodan da hanta.

Bugu da kari, yakamata a yi taka tsantsan yayin amfani da miyagun ƙwayoyi azaman sashi a cikin hadaddun jiyya na ciwon sukari na 2.

Umarnin don amfani da miyagun ƙwayoyi

Ana ɗaukar magani a baka. Mafi sau da yawa, kashi na warkewa da aka ba da shawarar don amfani shine 25 MG.

Morearin bayani daidai gwargwado na amfani da magani an wajabta shi ta likitan halartar la'akari da sakamakon da aka samu yayin binciken jikin mai haƙuri da halayensa na mutum.

Ana shan miyagun ƙwayoyi sau ɗaya a rana, ana shan maganin ba tare da la'akari da tsarin abinci ba. Shan maganin yana hade da shan ruwa mai yawa.

Yin amfani da magani yana yiwuwa a cikin halayen masu zuwa:

1. A matsayin magani ga monotherapy na type 2 ciwon sukari mellitus.
2. A cikin aiwatar da hadaddun lura da cutar, a matsayin bangaren irin wannan far. A kaikaice tare da vipidia, metformin, abubuwan da ake amfani da su na sulfonylurea ko insulin ana iya ɗauka.

A cikin batun Vipidia a hade tare da Metformin, ba a buƙatar yin gyare-gyare ga adadin maganin ba. Ana buƙatar yin gyaran gyare-gyare yayin amfani da miyagun ƙwayoyi a haɗaka tare da kwayoyi waɗanda keɓaɓɓun abubuwan da suka dace da maganin insulin.

Ana daidaita sashin don hana farkon alamun alamun yanayin hypoglycemic a cikin haƙuri tare da ciwon sukari mellitus.

Ya kamata a inganta hankali lokacin amfani da Vipidia a hade tare da Metformin Teva da thiazolidinedione a cikin maganin cututtukan sukari.

Lokacin da alamun farko na halayyar ƙwayar cuta suka bayyana, sashi na Metformin da thiazolidinedione ya kamata a rage.

Lokacin shan Vipidia, waɗannan sakamako masu illa na iya faruwa:

• daga tsarin juyayi, abin da ya faru na yawan ciwon kai,
• daga gastrointestinal fili, bayyanar zafi a cikin ciki, amai da abinda ke ciki na ciki a cikin esophagus, haɓaka alamun m pancreatitis,
• daga tsarin hepatobiliary, abubuwanda suka faru a cikin hanta,
• halayen rashin lafiyan na iya faruwa a cikin yanayin ƙyashi, rashes, edema Quincke,
• kumburi hanci da hanci da hancinsa mai yiwuwa ne,

Bugu da ƙari, sakamako masu illa daga tsarin rigakafi na iya faruwa, suna bayyana azaman anaphylaxis.

Neman bita akan Vipidia 25

A dandalin yanar gizo na yanar gizo akwai maganganu masu kyau daga masu harhada magunguna da shawarwari kan amfani da maganin.

Anastasia Sivorova, endocrinologist, Astrakhan.

Kyakkyawan kayan aiki a cikin yaki da ciwon sukari na 2. Mara lafiya haƙuri. A cikin aikin asibiti, bai hadu da hypoglycemia ba. Allunan yakamata a sha sau 1 a rana ba tare da yin lissafin hankali ba. Wakili na hypoglycemic daga sabon ƙarni, sabili da haka, ba ya ba da gudummawa ga karuwar nauyin jiki. Ana kiyaye aikin aikin ƙwayoyin beta na pancreatic.

Alexey Barredo, masanin ilimin dabbobi, Arkhangelsk.

Ina son wannan tare da tsawan amfani da miyagun ƙwayoyi, bayyananniyar bayyanannun ba sa ci gaba. Sakamakon warkewa yana da sakamako mai laushi cikin sauƙi, amma ba nan da nan za a iya ganuwa. Ya dace don ɗauka - lokaci 1 a rana. Kyakkyawan darajar kuɗi. Ba ya haifar da rashin lafiyan halayen a cikin marasa lafiya.

Analog na maganin shine Janavia.

Gabriel Krasilnikov, dan shekara 34, Ryazan.

Ina ɗaukar Vipidia a cikin kashi 25 na MG na tsawon shekaru 2 a cikin haɗuwa tare da 500 MG na Metformin da safe bayan cin abinci. Da farko, ya yi amfani da insulin daidai da makircin 10 + 10 + 8 raka'a. Bai taimaka wajen rage sukari da kyau ba. Ayyukan Allunan suna da tsawo. Sai bayan watanni 3, sukari ya fara faɗi, amma bayan watanni shida, glucose daga 12 ya faɗi zuwa 4.5-5.5. Yaci gaba da zama tsakanin 5.5. Ina son cewa nauyin ya ragu: daga 114 zuwa kilogiram 98 tare da haɓaka daga cm cm 180 Amma ya kamata ku bi duk shawarwarin daga umarnin.

Analogs a cikin kayan haɗin da nuni don amfani

Take	Farashi a Rasha	Farashi a Ukraine
Nesina alogliptin	--	--

Jerin da aka bayar na magungunan analogues na miyagun ƙwayoyi, wanda ke nuna Madubin Vipidia, ya fi dacewa saboda suna da tsari iri ɗaya na abubuwa masu aiki da daidaituwa bisa ga nuni don amfani

Analogs ta hanyar nuni da hanyar amfani

Take	Farashi a Rasha	Farashi a Ukraine
Janavia sitagliptin	1369 rub	277 UAH
Galvus vildagliptin	245 rub	895 UAH
Onglisa saxagliptin	1472 rub	48 UAH
Harshen trazhenta linagliptin	89 rub	1434 UAH

Abun daban-daban, na iya daidaituwa cikin nuni da hanyar aikace-aikace

Take	Farashi a Rasha	Farashi a Ukraine
Rosiglitazone mai mahimmanci, metformin hydrochloride	--	--
Bagomet Metformin	--	30 UAH
Glucofage metformin	12 rub	15 UAH
Glucophage xr metformin	--	50 UAH
Reduxin Metformin, Sibutramine	20 rub	--
Dianormet	--	19 UAH
Diaformin metformin	--	5 UAH
Metformin metformin	13 rub	12 UAH
Metformin sandoz metformin	--	13 UAH
Siofor	208 rub	27 UAH
Tsarin metformin hydrochloride	--	--
Emformorm EP Metformin	--	--
Megifort Metformin	--	15 UAH
Metamine Metformin	--	20 UAH
Metamine SR Metformin	--	20 UAH
Metfogamma metformin	256 rub	17 UAH
Tefor metformin	--	--
Glycometer	--	--
Glycomet SR	--	--
Formethine	37 rub	--
Metformin Canon metformin, ovidone K 90, sitaci masara, crospovidone, magnesium stearate, talc	26 rub	--
Insuffor metformin hydrochloride	--	25 UAH
Metformin-teva metformin	43 rub	22 UAH
Diaformin SR metformin	--	18 UAH
Mepharmil Metformin	--	13 UAH
Metformin Farmland Metformin	--	--
Glibenclamide Glibenclamide	30 rub	7 UAH
Maninyl Glibenclamide	54 rub	37 UAH
Glibenclamide-Kiwon lafiya Glibenclamide	--	12 UAH
Glyurenorm glycidone	94 rub	43 UAH
Bisogamma Glyclazide	91 rub	182 UAH
Glidiab Glyclazide	100 rub	170 UAH
Mai ciwon sukari MR	--	92 UAH
Diagnizide mr Gliclazide	--	15 UAH
Glidia MV Gliclazide	--	--
Glykinorm Gliclazide	--	--
Gliclazide Gliclazide	231 rub	44 UAH
Glyclazide 30 MV-Indar Glyclazide	--	--
Glyclazide-Health Gliclazide	--	36 UAH
Glioral Glyclazide	--	--
Diagnizide Gliclazide	--	14 UAH
Diazide MV Gliclazide	--	46 UAH
Osliklid Gliclazide	--	68 UAH
Diadeon gliclazide	--	--
Glyclazide MV Gliclazide	4 rub	--
Amaril	27 rub	4 UAH
Glemaz glimepiride	--	--
Gli karinda	--	77 UAH
Glimepiride Glyride	--	149 UAH
Glimepiride diapiride	--	23 UAH
Alfika	--	12 UAH
Glimax glimepiride	--	35 UAH
Glimepiride-Lugal glimepiride	--	69 UAH
Gwarwar Clay	--	66 UAH
Diabrex glimepiride	--	142 UAH
Meglimide glimepiride	--	--
Melpamide Glimepiride	--	84 UAH
Perinel glimepiride	--	--
Glempid	--	--
Glimed	--	--
Glimepiride dabarini	27 rub	42 UAH
Glimepiride-teva glimepiride	--	57 UAH
Glimepiride Canon dabarini	50 rub	--
Glimepiride Magungunan glimepiride	--	--
Dimaril glimepiride	--	21 UAH
Glamepiride lu'u-lu'u	2 rub	--
Amaryl M Limepiride Micronized, Metformin Hydrochloride	856 rub	40 UAH
Glibomet glibenclamide, metformin	257 rub	101 UAH
Glucovans glibenclamide, metformin	34 rub	8 UAH
Dianorm-m Glyclazide, Metformin	--	115 UAH
Dibizid-m glipizide, metformin	--	30 UAH
Douglimax glimepiride, metformin	--	44 UAH
Duotrol glibenclamide, metformin	--	--
Gluconorm	45 rub	--
Glibofor metformin hydrochloride, glibenclamide	--	16 UAH
Avandamet	--	--
Avandaglim	--	--
Janumet metformin, sitagliptin	9 rub	1 UAH
Velmetia metformin, sitagliptin	6026 rub	--
Galvus Met vildagliptin, metformin	259 rub	1195 UAH
Tripride glimepiride, metformin, pioglitazone	--	83 UAH
Haɗu da metformin XR, saxagliptin	--	424 UAH
Comboglyz Prolong metformin, saxagliptin	130 rub	--
Gentadueto linagliptin, metformin	--	--
Vipdomet metformin, alogliptin	55 rub	1750 UAH
Sinjardi empagliflozin, metformin hydrochloride	240 rub	--
Voglibose Oxide	--	21 UAH
Gzutazone dabari	--	66 UAH
Dropia Sanovel pioglitazone	--	--
Lixumia lixisenatide	--	2498 UAH
Guarem guar gum	9950 rub	24 UAH
Insvada ta sake	--	--
Samurai	30 rub	90 UAH
Sassan Ranka	--	--
Baeta Exenatide	150 rub	4600 UAH
Baeta Long Exenatide	10248 rub	--
Viktoza liraglutide	8823 rub	2900 UAH
Saxenda liraglutide	1374 rub	13773 UAH
Forksiga Dapagliflozin	--	18 UAH
Forsiga Dapagliflozin	12 rub	3200 UAH
Invocana canagliflozin	13 rub	3200 UAH
Jardins Empagliflozin	222 rub	566 UAH
Dulglutide Trulicity	115 rub	--

Yaya za a sami analog mai rahusa na magani mai tsada?

Don neman analog mai rahusawa ga magani, jana'iza ko alaƙa, da farko muna bada shawara a kula da abun da ke ciki, wato ga abubuwa masu aiki iri ɗaya da alamomi don amfani. Abubuwa masu aiki iri ɗaya na ƙwayoyi zasu nuna cewa maganin yana da alaƙa tare da miyagun ƙwayoyi, daidai da magunguna ko madadin magunguna. Koyaya, kar ka manta game da abubuwanda suka lalace na irin kwayoyi, wanda zai iya shafar aminci da tasiri. Kada ku manta game da umarnin likitoci, magani na kai na iya cutar da lafiyar ku, don haka koyaushe tuntuɓi likitanku kafin amfani da kowane magani.

Umarni Vipidia

INGANTA
kan amfani da kudade
Vipidia

Form sashi
12.5 MG da allunan da aka shirya fim 25 MG

Abun ciki
Tabletaya daga cikin kwamfutar hannu ya ƙunshi
abu mai aiki: alogliptin benzoate 17 MG (daidai yake da 12.5 MG na alogliptin) da 34 MG (daidai da 25 MG na alogliptin)
magabata:
Core: mannitol, celclosese na microcrystalline, hydroxypropyl cellulose, sirinum croscarmellose, magnesium stearate,
Abun cikin membrane fim: hypromellose 2910, titanium dioxide (E 171), iron oxide yellow (E 172), iron oxide ja (E 172), polyethylene glycol 8000, launin toka mai F1

Bayanin
Allunan otal biconvex, wanda aka lullube su da fim mai launin rawaya, mai taken "TAK" da "ALG-12.5" a gefe daya na kwamfutar (don sashi na 12.5 mg),
Allunan biconvex mai launi, wanda aka rufe fim din da launin ja mai haske, mai taken "TAK" da "ALG-25" a gefe ɗaya na kwamfutar (don sashi na 25 MG).

Rukunin Magunguna
Yana nufin don maganin ciwon sukari. Magungunan sukari na rage sukari don maganin baka. Masu hana ƙwayar dipeptidyl peptidase-4 (DPP-4). Alogliptin

Lambar ATX A10BH04

Kayan magunguna
Pharmacokinetics
An bincika magunguna na maganin alogliptin a cikin binciken da ya shafi duka masu ba da lafiya da marasa lafiya da ke fama da ciwon sukari na 2.A cikin masu ba da agaji na lafiya, bayan gudanar da maganin guda ɗaya na har zuwa 800 MG na alogliptin, ana lura da saurin shan ƙwayoyi tare da mafi yawan ƙwayar plasma na sa'a daya zuwa biyu daga lokacin gudanarwa (matsakaita Tmax). Bayan shan matsakaicin maganin warkewar magani (25 MG), ƙarshen rabin rayuwar (T1 / 2) ya wadatar da sa'o'i 21.
Bayan sake maimaitawa na har zuwa 400 MG na kwanaki 14 a cikin marasa lafiya da ke da nau'in ciwon sukari na 2, an lura da ƙaramin tarin yawa na alogliptin tare da karuwa a yankin a ƙarƙashin tsarin kula da magunguna (AUC) da mafi yawan ƙwayar plasma (Cmax) ta 34% da 9%, bi da bi. Tare da allurai guda da yawa na alogliptin, AUC da Cmax suna ƙaruwa da haɓaka da karuwar kashi daga 25 MG zuwa 400 MG. Coarancin canji na AUC na alogliptin a cikin marasa lafiya karami ne (17%).
Damuwa
Cikakken bayanin halitta na alogliptin kusan kashi 100% ne. Tun lokacin da ake ɗaukar ɗanɗano tare da abinci tare da mai mai mai yawa, ba a sami sakamako a kan AUC da Cmax ba, ana iya shan maganin ba tare da la'akari da abincin ba.
Rarraba
Bayan gudanarwa guda ɗaya na maganin alogliptin a kashi 12.5 MG a cikin masu sa kai masu lafiya, ƙarar rarraba a cikin tashar tashar shine 417 L, wanda ke nuna cewa anlogliptin an rarraba shi sosai cikin kyallen takarda.
Sadarwa tare da sunadaran plasma shine 20%.
Tsarin rayuwa
Alogliptin baya fuskantar matsanancin metabolism, sakamakon wanda daga 60% zuwa 71% na maganin da aka gudanar an cire shi wanda baya canzawa a cikin fitsari. Bayan sarrafawar bakin mutum na 14C-mai lakabin alogliptin, an ƙaddara ƙananan metabolites: N-demethylated alogliptin M-I (˂1% na kayan farawa) da N-acetylated alogliptin M-II (˂6% na kayan farawa). M-I shine metabolite mai aiki da mai hana inhibitor na DPP-4, mai kama da aiki don alogliptin, M-II baya nuna aikin inhibitory akan DPP-4 ko wasu enzymes DPP-kamar. Nazarin cikin vitro ya nuna cewa CYP2D6 da CYP3A4 suna ba da gudummawa ga iyakance metabolism na alogliptin. Alogliptin ya kasance mafi yawa a cikin nau'i na (R) enantiomer (> 99%) kuma a ƙarƙashin yanayin vivo yana ɗaukar ƙananan juzu'i na jujjuyawar ƙwayar cuta zuwa (S) enantiomer. (S) -enantiomer ba a gano shi ba yayin shan alogliptin a allurai warkewa (25 mg).
Kiwo
Bayan gudanar da aikin alogliptin mai nauyin 14C, 76% na yawan aikin rediyo yana cire ƙodan da 13% ta cikin hanji, sun kai 89% na maganin rediyo da aka gudanar. Enaladdamar da azabtarwa na alogliptin (9.6 L / h) yana nuna ɓoye ɓarawon koda. Tsarin tsarin shine 14.0 l / h.
Pharmacokinetics a cikin rukunin masu haƙuri na musamman:
Paarancin aiki na haya
AUC na alogliptin a cikin marasa lafiya da ke fama da rauni na wucin gadi mai rauni (60≤ creatinine clearance (CrCl) Dukkanin bayanan an gabatar dasu ne don dalilai na sanarwa kuma ba dalili bane don keɓance kansa ko maye gurbin miyagun ƙwayoyi

Kudin Vipidia da misalanta

Yin amfani da allunan Vipidia don ciwon sukari galibi tabbatacce ne.

Idan muka yanke hukunci game da maganin ta hanyar bita da mutane da ke amfani da Vipidia suka bar game da shi, zamu iya yanke hukuncin cewa magani ne mai matukar tasiri wanda zai iya sarrafa matakin glycemia sosai a jikin mutumin da ke fama da ciwon sukari na 2.

Magunguna suna amfani da kayan aiki, wanda shine alogliptin har zuwa yau, ban da Vipidia ba rajista.

Kwayoyin magunguna masu tasowa, abubuwanda suke aiki wanda sune abubuwanda ke cikin rukunin incretinomimetics.

Magungunan da suka fi yawan amfani da su analogues na Vipidia sune kamar haka:

1. Januvia magani ne mai ƙwarin jini wanda aka kirkira shi bisa asalin sitagliptin. Sakin maganin yana cikin nau'ikan allunan da ke dauke da 25, 50 da 100 MG na kayan aiki masu aiki. Abubuwan da ake nunawa don amfani da Janavia sun yi kama da waɗanda Vipidia ke da shi. Za'a iya amfani da wannan magani tare da monotherapy ko tare da magani mai wahala.
2. Yanumet wani shiri ne mai hadaddun, wanda ya qunshi sitagliptin da metformin a matsayin kayan aiki masu aiki. Sashin kashi na farko na aiki shine 50 MG, kuma metformin a cikin abun da ke cikin miyagun ƙwayoyi na iya kasancewa a cikin adadi mai yawa. Akwai magungunan a cikin nau'ikan guda uku - 50, 850 da 1000 mg.
3. Galvus a matsayin sashin aiki mai aiki ya ƙunshi vildagliptin, wanda shine analogliptin analog ne. Sashi na aiki mai aiki a cikin shiri shine 50 MG. Yawan sashi na metformin a cikin kwayoyin shine 500, 850, da 1000 mg.
4. Onglisa a cikin kayanta a matsayin fili mai aiki yana dauke da saxagliptin. Wannan kwayar ta danganta ga mahadi wadanda ke hana iskancin enzyme wanda ke lalata abubuwanda ke faruwa. Ana amfani da maganin a cikin sashi na 2.5 da 5 MG.
5. Comboglyz Prolong shine haɗakar saxagliptin tare da metformin. Ana samun wannan maganin ta hanyar kwamfutar hannu. Sakin abubuwa masu aiki suna faruwa ne cikin tsari jinkiri.
6. Trazhenta magani ne na hypoglycemic wanda aka yi akan tushen linagliptin. Abun da ke cikin magani ya ƙunshi 5 MG na kayan aiki mai aiki.

Kudin magani ya dogara da yankin da ake siyar da miyagun ƙwayoyi a Rasha. Matsakaicin farashin wannan magani shine 843 rubles.

Abin da sauran magunguna za a iya amfani dashi don magance cututtukan sukari an bayyana shi a cikin bidiyo a wannan labarin.