Maninil (Glibenclamide)

Ciwon sukari mellitus na ɗaya daga cikin manyan cututtukan mutum na zamani. Ba tare da magunguna na musamman ba, mutanen da suke da wannan matsalar ba za su iya rayuwa ba. Kuma ba shakka, ya kamata a zabi maganin cutar sankara don daidai. Mafi sau da yawa, likitoci suna ba da ingantaccen magani "Maninil" ga marasa lafiya. Umarnin don amfani, farashi, sake dubawa, alamomi na wannan magani - zamuyi magana game da duk wannan daga baya a labarin.

Ana bayar da wannan maganin ta hanyar Allunan. Babban sinadari mai aiki shine g libenclamide. Tabletaya daga cikin kwamfutar hannu ɗaya na wannan abun zai iya ƙunsar 3.5 ko 5 MG. Hakanan, abun da ke tattare da maganin ya hada da lactose, sitacin dankalin turawa, silicon dioxide da wasu abubuwan hade. Kamfanin na Che Cheril na Berlin ya dukufa wajen sakin wannan maganin.

Magungunan "Maninil" yana da tsada. Farashinsa kusan 150-170 p. na allunan 120.

A cikin wane yanayi ne aka tsara contraindications

Da zarar cikin jikin mai haƙuri, miyagun ƙwayoyi "Maninil" (analogues dinsa na iya yin aiki daban) yana ƙara hankalin mai karɓar insulin. Yana da sinadarin aiki na wannan maganin da sauran fa'idoji masu amfani akan jikin mai haƙuri. Maninil, a tsakanin sauran abubuwa, yana da ikon haɓaka samar da insulin na halitta.

Alamu don amfani da wannan magani shine ciwon sukari na 2. Wannan maganin zai iya ba da izinin likita ta hanyar endocrinologist kawai. Contraindications wa yin amfani da su sune:

nau'in ciwon sukari guda 1

coma mai cutar kansa

ciki da lactation,

mai girma renal ko hanta gazawar,

rage farin jinin sel count.

Yadda ake amfani

Don Allunan 5 MG daidai yake da na miyagun ƙwayoyi "Manin 3.5", umarnin don amfani. Farashin (analogues na miyagun ƙwayoyi na iya samun farashi daban-daban) na wannan magani, kamar yadda aka ambata a baya, yana daɗaɗɗa. Bugu da kari, likitoci suna tsara shi ga marasa lafiya kyauta, sabanin masu sauyawa masu sauki, da wuya. Abin da ya sa mutane da yawa marasa lafiya ke sha'awar ko wannan maganin yana da ƙarancin analogues mai rahusa. Ana samun irin waɗannan kwayoyi a cikin kantin magani. Amma kafin ci gaba zuwa bayanin su, zamu ga wane umarnin don amfani da samfurin Manilin da kanta duk da haka yana da.

Likita ya zaɓi adadin wannan maganin ga mai haƙuri daban-daban. Yawan maganin da aka sha a rana sau ɗaya ya dogara da matakin glucose a cikin fitsari. Sun fara shan wannan maganin yawanci tare da ƙaramin magani. Hakanan, ƙarshen yana ƙaruwa. Mafi sau da yawa, a matakin farko, ana wajabta mai haƙuri rabin kwamfutar hannu a kowace rana (dangane da sakamakon binciken, 3.5 ko 5 MG). Bayan haka, kashi yana ƙaruwa da babu kwamfutar hannu sama da ɗaya a mako ɗaya ko kwanaki da yawa.

Reviews game da "Maninil"

Wannan ne umarnin amfani da aka bayar don maganin “Maninil”. Analogues na wannan miyagun ƙwayoyi suna da yawa sosai. Amma "Maninil" yawancin marasa lafiya suna la'akari da watakila mafi kyawun kayan aiki a rukunin su. Ra'ayoyin marasa lafiya da ciwon sukari mellitus game da wannan magani ya inganta sosai. Ya taimaka, bisa ga yawancin masu amfani, kawai lafiya. Koyaya, rashin alheri, wannan magani bai dace da duk marasa lafiya ba. Yana kawai ba ya zuwa wasu marasa lafiya.

A kowane hali, ba tare da togiya ba, marasa lafiya suna ba da shawarar shan wannan maganin na musamman a sashi na likita wanda ya ba da shawarar. In ba haka ba, miyagun ƙwayoyi na iya haifar da maye.

Menene analogues na maganin "Manin"

Akwai abubuwa da yawa waɗanda ke maye gurbin wannan magani a kasuwar zamani. Wasu daga cikinsu sun sami kyakkyawan kimantawar masu amfani, yayin da wasu ba su samu ba.

A mafi yawancin halayen, mutane masu ciwon sukari suna amfani da analogs tare da sunaye masu zuwa maimakon "Maninil":

Wani lokaci marasa lafiya suna sha'awar ko akwai isharar ana Manil 3.5 mg (Allunan) akan kasuwa. Babu kusan babu ma'anar wannan maganin a kasuwar magunguna ta zamani. Yawancin analogues ana yin su ne bisa ga wasu abubuwa masu aiki. Sabili da haka, gwargwadon abun da ke ciki a cikin allunan maye gurbin daban-daban. Iyakar yanayin maninil kawai shine Glibenclamide. Za'a iya sayan wannan madadin a cikin sashi na 3.5 MG.

Maganin "Glibenclamide"

Alamu da contraindications na wannan magani daidai suke da na "Maninil" kanta. Bayan haka, a zahiri, wannan magani shine asalinsa mai arha. Wannan magani ya cancanci a cikin magunguna game da 80-90 p. Kodayake abu mai aiki iri ɗaya ne ga duka waɗannan magungunan, maye gurbin Maninil tare da Glibenclamide an yarda da shi kawai akan shawarar likita. Ciwon sukari mellitus cuta ce babba. An samar da wannan magani a Ukraine.

Ra'ayin marasa lafiya akan Glibenclamide

Kamar Maninil, sake dubawa (analogues na wannan miyagun ƙwayoyi tare da sauran abubuwa masu aiki ga marasa lafiya sau da yawa mafi muni), wannan magani daga masu amfani da shi ya sami nagarta. Baya ga tasiri, ayyukan da amfanin wannan magani, mutane da yawa marasa lafiya sun danganta da ƙarancin kuzari da sauƙi na rarraba allunan. Yawancin marasa lafiya suna ɗaukar magunguna na Glibenclamide da aka ƙera a Kiev a matsayin mafi ƙimar inganci. Allunan Kharkov yayin rarrabuwa, da rashin alheri, zasu iya crumble.

Magani "Ciwon sukari"

Ana samun wannan maganin ta hanyar farin allunan fararen oval. Babban sashi mai aiki shine glycoside. Kamar Maninil, Diabeton yana cikin rukunin abubuwan rage sukari na mutanen ƙarshe. Babban fa'idar wannan magani shine, ban da inganci, rashin shan giya. Ba kamar Maninil ba, Diabeton yana ba ka damar mayar da farkon fari kuma yana hana haɓakar hyperinsulinemia. Amfanin wannan kayan aiki, idan aka kwatanta da sauran magunguna na wannan rukunin, sun haɗa da cewa yana da damar rage ƙwayar jini.

Reviews on "Ciwon sukari"

Yawan sukari a cikin jini, a cewar mafi yawan masu cutar, wannan maganin yana rage kyau sosai. Tasirin sakamako, a cewar masu cin abinci, "Ciwon sukari" yana bada wuya da wuya. Mafi yawan marasa lafiya sun danganta rashin ingancin wannan magani musamman saboda tsadar sa mai yawa. Dole ne ku biya ƙarin don shi fiye da na Maninil. Analogs (farashin magungunan da ake amfani da shi don cutar sankara na iya bambanta sosai) na wannan magani yawanci mai rahusa ne. Diabeton ne togiya a wannan batun. Akwai kunshin allunan 60 na wannan samfurin a cikin magunguna na umarnin 300 r. Wannan magani ya dace, kamar yawancin magunguna masu rage sukari, da rashin alheri, ba ga duk masu haƙuri ba.

Magungunan "Metformin"

Hakanan ana samun magungunan a allunan da magunguna da kuma asibitocin. Babban sashi mai aiki shine metformin hydrochloride. Tasirin magunguna na wannan wakili an bayyana shi da gaske a cikin gaskiyar cewa yana rage yawan adadin sukari daga hanji. Ba ya yin tasiri a kan aikin samar da insulin, kamar Glibenclamide da Maninil. Ofaya daga cikin tabbatattun fa'idodin wannan maganin shine cewa ba ya haifar da bayyanar alamun hypoglycemia a cikin jiki.

Ra'ayoyi game da Metformin

Marasa lafiya suna yabon wannan magani da farko saboda aikinsa mai laushi. Metformin ya sami kyakkyawan ra'ayoyi kuma a zahiri cewa tare da amfanin sa yana yiwuwa ba kawai don magance cutar sankara ba a zahiri. Yana inganta amfani da wannan magani da asarar nauyi. Kamar Diabeton, wannan magani, a tsakanin sauran abubuwa, yana rage cholesterol a cikin jinin marasa lafiya. Hakanan ana amfani da ƙari da wannan samfurin kuma ba farashin mai yawa bane: allunan 60 na Metformin sunkai kimanin 90 r.

Wasu daga cikin raunin wannan magani, masu amfani sun danganta kawai cewa a cikin farkon watanni na shan shi, zai iya tayar da zawo. Irin wannan sakamako wani gefen Maninil ne yake ba da ita. Analogs dinsa sau da yawa ma sun bambanta a cikin abu ɗaya. Amma sakamako na gaba a cikin nau'in zawo a cikin yawancin waɗannan kwayoyi yawanci har yanzu ba a faɗi hakan ba.

Magungunan "Glimepiride" ("Amaril")

An yi wannan maganin ne ta hanyar wani abu da ake kira glimepiride. Yana da tasiri mai rikitarwa a jikin mai haƙuri - yana ƙarfafa glandar, yana hana samar da sukari a cikin hanta, kuma yana ƙara haɓaka kyallen takarda zuwa aikin hormone. Wannan magani yana rage haɗarin haɓakar kamuwa da cututtukan cututtukan cututtukan zuciya. Mafi yawancin lokuta, likitoci suna yin wasiyya da Amaril a lokaci guda kamar Metformin. Akan siyarwa a yau akwai kuma magani, wanda yake cakuda abubuwa masu aiki na duk waɗannan kuɗin. Ana kiranta Amaril M.

Nazarin Magunguna

Ra'ayoyin game da wannan magani a cikin mutanen da ke da ciwon sukari yana da kyau kwarai da gaske. Tasirin amfanin sa yawanci ana lura dashi. An yi imani da cewa yin amfani da wannan magani ya fi kyau idan Metformin kadai bai taimaka ba. Girman katunan Amarin suna da yawa. Bugu da ƙari, suna da haɗari. Don haka, raba su idan ya cancanta ya dace sosai.

Maganin "Glucophage"

Wannan magani yana da alaƙa da Metformin. Abubuwan da ke aiki daidai daidai ne a gare shi. Guda ɗaya ke faruwa don alamomi da kuma contraindications. Kamar Metformin, wannan maganin yana da tasiri mai sauƙin tasiri a jikin mai haƙuri. Hakanan yana rage nauyi sosai.

Maimakon ƙarshe

Don haka, mun gano menene "Maninil" (umarnin don amfani, farashi, analogues yanzu an san ku). Wannan maganin, kamar yadda kake gani, yana da tasiri. Yawancin takwarorinsu ma sun cancanci kyakkyawan ƙididdigar marasa lafiya. Koyaya, wajibi ne don amfani da wannan magani kuma maye gurbin shi da wasu kwayoyi tare da tasirin warkewa iri ɗaya, ba shakka, kawai kan shawarar likita.

Aikin magunguna

Oral hypoglycemic magani daga rukuni na sulfonylurea abubuwan asali na ƙarni na biyu.

Yana ƙarfafa insulin insulin ta hanyar ɗaura wa membrane ƙwayar ƙwayar ƙwayar cuta musamman, yana rage ƙonewa don haɓakar glucose β-cell, haɓaka ƙwarewar insulin da ɗaurin ɗaukar ƙwayar cuta, yana ƙaddamar da sakin insulin, yana inganta tasirin insulin akan ƙwayar tsoka. da hanta, ta haka ne rage haduwar glucose a cikin jini. Ayyukan Manzanni a mataki na biyu na insulin ɓoyewar insulin. Yana hana lipolysis cikin nama adipose. Yana da tasirin rage kiba, yana rage kaddarorin jini na jini.

Maninil® 1.5 da Maninil® 3.5 a cikin tsarin micronized babban fasaha ne, musamman nau'in glibenclamide, wanda ke ba da damar amfani da ƙwayar ƙwayar cuta daga hanji cikin hanzari. Dangane da nasarar farko na Cmax na glibenclamide a cikin plasma, tasirin hypoglycemic kusan yayi dace da karuwar lokacin glucose a cikin jini bayan cin abinci, wanda ke sa tasirin miyagun ƙwayoyi da ƙoshin lafiya. Tsawon lokacin aikin hypoglycemic shine 20-24 hours.

Tasirin hypoglycemic na miyagun ƙwayoyi Maninil® 5 yana tasowa bayan sa'o'i 2 kuma yana ɗaukar sa'o'i 12.

Pharmacokinetics

Bayan shigowa da Maninil 1.75 da Maninil 3.5, ana lura da sauri da kusan cikakkiyar ƙwayar jijiyoyin. Cikakken sakin abubuwan da ke aiki na microionized na faruwa a cikin mintuna 5.

Bayan shigowa da Maninil 5, sha daga ciki shine kashi 48-84. Tmax - awa 1-2. Cikakken bioavailability - 49-59%.

Tabbatar da furotin na Plasma ya fi 98% na Maninil 1.75 da Maninil 3.5, 95% na Maninil 5.

Metabolism da excretion

An kusan kusan metabolized a cikin hanta tare da ƙirƙirar metabolites guda biyu marasa aiki, ɗayan wanda kodan ya keɓe, ɗayan kuma da bile.

T1 / 2 don Maninil 1.75 da Maninil 3.5 shine 1,5 hours 1.5-3.5, don Maninil 5 - 3-16 hours.

Sakawa lokacin

Likita ya saita adadin magungunan daban-daban dangane da tattarawar glucose a cikin jini akan komai a ciki da sa'o'i 2 bayan cin abinci.

Kashi na farko na maganin Maninil 1.75 shine kwamfutar hannu 1 / 2-1 sau 1 a rana. Tare da rashin isasshen tasiri a ƙarƙashin kulawar likita, ana samun ƙara yawan ƙwayar ƙwayar cuta har sai an saka kullun don buƙatar daidaita metabolism metabolism. Matsakaicin adadin yau da kullun shine Allunan 2 (3.5 MG). Matsakaicin adadin yau da kullun shine Allunan 3 (a lokuta na musamman, Allunan 4).

Idan ya zama dole a dauki karin allurai, sai su canza zuwa shan Maninil 3.5.

Maganin farko na Maninil® 3.5 shine allunan 1 / 2-1 sau 1 a rana. Tare da rashin isasshen tasiri a ƙarƙashin kulawar likita, ana samun ƙara yawan ƙwayar ƙwayar cuta har sai an saka kullun don buƙatar daidaita metabolism metabolism. Matsakaicin adadin yau da kullun shine Allunan 3 (10.5 mg). Matsakaicin adadin yau da kullun shine Allunan 4 (14 MG).

Ya kamata a sha miyagun ƙwayoyi kafin abinci, ba tare da taunawa ba kuma shan ɗan adadin ruwa. Yawan magunguna na yau da kullun har zuwa allunan 2 yakamata a sha sau ɗaya a rana - da safe, kafin karin kumallo. Manyan allurai sun kasu kashi biyu na safe da maraice. Idan kun tsallake kashi ɗaya na miyagun ƙwayoyi, ya kamata a ɗauka kwamfutar hannu ta gaba a lokacin da aka saba, alhali ba a ba da izinin shan magani mafi girma ba.

Maganin farko na Maninil® 5 shine 2.5 mg 1 lokaci a rana. Tare da rashin isasshen tasiri, a karkashin kulawar likita, ana amfani da ƙarancin maganin a cikin 2.5 MG a kowace rana tare da tazara tsakanin kwanaki 3-5 har sai an cika sashi na yau da kullun don daidaita metabolism metabolism. Aikin yau da kullun shine 2.5-15 mg.

Magungunan fiye da 15 MG kowace rana ba su ƙaruwa da mummunan tasirin hypoglycemic na miyagun ƙwayoyi.

A cikin marasa lafiya tsofaffi, akwai haɗarin haɓakar hypoglycemia, sabili da haka, a gare su, kashi na farko ya kamata ya zama 1 MG kowace rana, kuma ya kamata a zaɓi sashin tabbatarwa a ƙarƙashin kulawar likita.

Mitar shan miyagun ƙwayoyi Maninil® 5 shine sau 1-3 a rana. Ya kamata a sha miyagun ƙwayoyi minti 20-30 kafin cin abinci.

Lokacin sauya daga wasu wakilai na hypoglycemic tare da irin wannan hanyar aiwatarwa, an tsara Maninil® 5 bisa ga tsarin da ke sama, kuma an soke maganin da ya gabata. Lokacin canzawa daga biguanides, kashi na farko na yau da kullun shine 2.5 MG, idan ya cancanta, ana ƙara yawan adadin yau da kullun a kowace 5-6 na kwanaki ta 2.5 mg har sai an sami sakamako. In babu diyya a cikin makonni 4-6, ya zama dole yanke shawara game da hanyoyin haɗuwa tare da insulin.

Side sakamako

Sakamakon mummunan sakamako a cikin jiyya tare da Maninil® shine hypoglycemia. Wannan yanayin na iya ɗaukar yanayi mai nisa kuma yana bayar da gudummawa ga ci gaban mawuyacin yanayi (har zuwa cutar mara ƙima ko ƙarewa). Tare da tsari mai sauƙi, polyneuropathy na masu ciwon sukari ko tare da kulawa mai gamsarwa tare da wakilai na juyayi, hanyoyin kwantar da hankali na iya zama mai laushi ko a rabe gaba ɗaya.

Abubuwan da ke haifar da ci gaban hypoglycemia na iya zama: yawan shan ƙwayoyi, nuni mara daidai, abincin da bai dace ba, tsofaffi marassa lafiya, amai, zawo, tsananin motsa jiki, cututtukan da ke rage buƙatar insulin (lalacewar hanta da aikin koda, hauhawar jini ta hanzari, ƙwayar ƙwayar cuta ko glandar thyroid) , shan giya, da ma'amala da wasu magunguna.

Bayyanar cututtukan hypoglycemia sun hada da matsananciyar yunwar, satar bazata kwatsam, palpitations, pallor na fata, paresthesia a baki, rawar jiki, damuwa ta gaba daya, ciwon kai, matsanancin damuwa, tashin hankali, jin tsoro, rashin daidaituwa game da motsi, rikicewar jijiyoyin wucin gadi (misali, cuta hangen nesa da magana, bayyanar paresis ko gurguwa ko canza tsinkaye). Tare da ci gaban hypoglycemia, marasa lafiya na iya rasa ikon kamewa da sanin su. Sau da yawa irin wannan mara lafiya yana da rigar, m fata da preisposition zuwa ga cramps.

Hakanan za'a iya haifar da sakamako masu biyo baya

Daga tsarin narkewa: da wuya - tashin zuciya, belching, amai, dandano mai ƙarfe a cikin bakin, jin nauyi da cikar ciki, ciwon ciki da gudawa, a wasu yanayi - karuwa na ɗan lokaci cikin ayyukan hanta enzymes na hanta (GSH, GPT, ALP), maganin cutar hepatitis da jaundice.

Allergic halayen: kurji, pruritus, urticaria, redness na fata, Quincke ta edema, hemorrhages a cikin fata, flaky fyaɗe a kan manyan saman fata, ƙara hotoensitivity. Da wuya, halayen fata na iya zama farkon haɓakar yanayi mai wahala, tare da nessarfin numfashi da raguwar hauhawar jini har zuwa farkon girgiza, wanda ke barazanar rayuwar mai haƙuri. Wasu lokuta na mummunan halayen halayen rashin lafiyan jiki tare da fatar fata, zafin hadin gwiwa, zazzabi, bayyanar sunadarai a cikin fitsari da kuma jaundice an bayyana su.

Daga tsarin haiatopoietic: da wuya - thrombocytopenia, erythropenia, leukocytopenia, agranulocytosis, a cikin sassan da aka kebe - hemolytic anemia or pancytopenia.

Sauran: a cikin yanayin da aka kewaya, raunin diuretic mai rauni, bayyanar na ɗan lokaci na furotin a cikin fitsari, hangen nesa da wurin zama, kazalika da mummunan sakamako na rashin haƙuri yayin shan giya, wanda aka bayyana ta rikitarwa na jijiyoyin jiki da gabobin jiki na ciki (amai, jin zafi a fuska da babba jiki) , tachycardia, dizziness, ciwon kai).

Contraindications zuwa ga yin amfani da miyagun ƙwayoyi MANINIL®

• nau'in ciwon sukari guda 1
• mai ciwon sukari ketoacidosis, maganin ciwon sukari da coma,
• yanayi bayan kamanceceniya,
• mai lalata hanta,
• mai saurin lalata na yara (CC kasa da 30 ml / min),
• wasu yanayi masu tsauri (alal misali, zubar da metabolism na metabolism a cikin cututtukan cututtuka, ƙonewa, raunin da ya faru ko bayan manyan tiyata lokacin da aka nuna maganin insulin),
• leukopenia
• hanji na ciki, paresis na ciki,
• yanayi tare da malabsorption abinci da haɓakar cututtukan jini,
• ciki
• lactation (shayarwa),
• sanannen hypersensitivity zuwa glibenclamide da / ko wasu abubuwan da suka samo asali na sulfonylurea, sulfonamides, diuretics (diuretics) wanda ke dauke da rukuni na sulfonamide a cikin kwayar, kuma ga probenecid, tunda halayen giciye na iya faruwa.

Tare da taka tsantsan, ya kamata a tsara magungunan don cututtukan febrile, cututtukan thyroid (tare da aiki mai rauni), hypofunction na ciwon huhun ciki ko adrenal cortex, barasa, a cikin tsofaffi marasa lafiya saboda da yiwuwar haɓakar haɓaka.

Umarni na musamman

Yana da Dole a sa ido a kai a kai yayin tattara yawan glucose a cikin jini akan komai a ciki kuma bayan cin abinci.

Ya kamata a faɗakar da marassa lafiya game da haɗarin haɗarin hypoglycemia a cikin lokuta na ethanol ci (ciki har da haɓakar cutar disulfiram-like syndrome: zafi na ciki, tashin zuciya, amai, amai) da kuma lokacin yunwar.

Likita yakamata yayi la’akari da nadin maganin na Maninil patients ga marassa lafiyar da ke fama da hanta da kuma koda, da kuma tsotsar zuciya, ciwon ciki da na ciki.

Gyara matakan magani na Maninil® ya wajaba don wuce gona da iri da motsin rai, canjin abinci.

Yayin jiyya, ba da shawarar zama a rana na dogon lokaci.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

A cikin lokacin har sai an samar da mafi kyawun ƙwayar cuta ko lokacin da ake canza ƙwayoyi, kamar yadda tare da gudanarwa na yau da kullun na maganin Maninil®, ikon fitar da mota ko sarrafa abubuwa daban-daban, kazalika da shiga cikin wasu ayyukan haɗari masu haɗari waɗanda ke buƙatar ƙara kulawa da saurin ƙwaƙwalwa da motsa jiki, mai yiwuwa ne .

Yawan abin sama da ya kamata

Bayyanar cututtuka: ƙarancin yawan shan magunguna Maninil®, tare da tsawanta yin amfani da miyagun ƙwayoyi a cikin allurai masu ƙarfi, na iya haifar da matsanancin hauhawar jini, wanda a lokuta da dama na yin barazanar rayuwar mai haƙuri.

Jiyya: yanayi mai laushi na hypoglycemia, shine farkon abubuwanda suka fara amfani dashi, mai haƙuri zai iya kawar da kansa ta kai tsaye cin wani sukari, jam, zuma, shan gilashin shayi mai zaki ko kuma maganin glucose. Sabili da haka, mai haƙuri koyaushe ya kasance tare da shi piecesan sugaranyen sukari da aka sabunta ko abinci mai ƙanshi (alewa). Kayan kayan kwalliya da aka yi musamman ga marasa lafiya da ke dauke da cutar siga baya taimakawa a cikin irin wannan yanayi. Idan mai haƙuri ba zai iya kawar da alamun hypoglycemia nan da nan ba, to dole ne ya kira likita nan da nan. Game da ƙwaƙwalwar ƙwaƙwalwar ƙwayar cuta, 40% dextrose bayani ne allura a ciki / a, i / m 1-2 mg na glucagon. Bayan ya dawo cikin tunani, dole ne a bai wa mai haƙuri abincin da ke da wadataccen abinci mai narkewa a cikin ƙwayoyin cuta mai sauƙi (don guje wa sake haɓakawar hypoglycemia).

Hulɗa da ƙwayoyi

Ya kamata a sami haɓakar sakamako na hypoglycemic na shirye-shiryen Maninil® a cikin waɗannan lokuta lokacin da ake jiyya tare da masu hana ACE, wakilai na anabolic, sauran magungunan maganganu na baka (alal misali, acarbose, biguanides) da insulin, azapropasone, beta-blockers, quinine, quinolone, chloram derivatives da kuma analogs, magungunan coumarin, rashin biyayya, fenfluramine, pheniramidol, fluoxetine, MAO inhibitors, miconazole, PASK, pentoxifylline (a cikin manyan allurai) ah parenterally), perhexiline, abubuwan pyrazolone, phenylbutazones, phosphamides (misali cyclophosphamide, ifosfamide, trophosphamide), probenecid, salicylates, sulfinpyrazone, sulfanilamides, tetracyclines, tritokvalin, tare da shan barasa.

Manyan acid urine (ammonium chloride, alli chloride) suna haɓaka tasirin magungunan Maninil® ta hanyar rage darajar rarrabuwarta da haɓaka aikinta.

Tare da karuwa a cikin tasirin hypoglycemic, beta-blockers, clonidine, guanethidine da reserpine, har ma da kwayoyi tare da kayan aiki na tsakiya na aiki, na iya raunana tunanin abubuwan da ke haifar da rashin lafiyar hypoglycemia.

Tasirin hypoglycemic na Maninil® na iya raguwa tare da amfani da lokaci guda na barbiturates, isoniazid, cyclosporine, diazoxide, GCS, glucagon, nicotinates (a cikin babban allurai), phenytoin, phenothiazines, rifampicin, saluretics, acetazolamide, hormonal sex, eal. glandar thyroid, jami'ai masu tausayawa, indomethacin da kuma sinadarin lithium.

Rashin giya na yau da kullun na barasa da kuma maganin maye gurbi na iya haifar da take hakkin metabolism.

Masu antagon masu karɓar H2 na iya yin rauni, a gefe guda, kuma, a gefe guda, haɓaka tasirin hypoglycemic na Maninil®.

A cikin halayen da ba a sani ba, pentamidine na iya haifar da raguwa mai ƙarfi ko haɓaka cikin haɗuwar glucose jini.

Ta yin amfani da magani na Maninil® na lokaci guda, tasirin abubuwan coumarin na iya ƙaruwa ko raguwa.

Magungunan da ke hana haɓakar ƙwaƙwalwar kashi suna ƙara haɗarin cutar myelosuppression yayin amfani da shi tare da Maninil®.

Yakamata a sanarda mara lafiyar likita game da yiwuwar hulda.

Formaddamar da tsari da abun da ke ciki

An samar da maganin a cikin nau'ikan Allunan wanda ke dauke da 1.75 mg, 3.5 mg ko 5 mg na glibenclamide.

Abubuwan da aka haɗa a cikin Maninyl 1.75 da 3.5 sune lactose monohydrate, sitaci dankalin turawa, hemetellose, silicon colloidal dioxide, magnesium stearate, Pintor 4 P, Maninil 5 - lactose monohydrate, sitaci masara, magnesium stearate, gelatin, talc Ponce danson 4R.

Alamu don amfani

Dangane da bayanin da aka ƙayyade a cikin umarnin Maninil, an yi amfani da wannan maganin don magance nau'in ciwon sukari na 2, duka biyu a matsayin maganin ƙwaƙwalwar ƙwaƙwalwa kuma a matsayin wani ɓangare na maganin haɗuwa tare da sauran wakilai na maganganu na baka, ban da yumɓu da abubuwan ƙira na sulfonylurea.

Sashi da gudanarwa

Matsayin Maninil yana ƙaddara ta hanyar halartar likita dangane da tsananin yanayin cutar, shekarun mai haƙuri, yawan faɗuwar cutar glucose jini da sa'o'i biyu bayan cin abinci.

Kashi na farko na maganin shine:

• Maninil 1.75 - 1-2 Allunan sau ɗaya a rana,
• Maninil 3.5 da 5 - 1 / 2-1 shafin. sau daya a rana.

Tare da rashin isasshen tasiri, ƙwayar sannu-sannu ana ƙaruwa har sai an daidaita ƙwayar carbohydrate. Theara yawan kashi ana aiwatar da shi a hankali, a lokaci-lokaci daga yawancin kwanaki zuwa mako guda.

Matsakaicin adadin yau da kullun:

• Maninil 1.75 - allunan 6,
• Maninil 3.5 da Allunan 5 - 3.

Ya raunana marasa lafiya, mutanen da suka tsufa, marasa lafiya da rage yawan abinci mai gina jiki, hanta mai rauni ko aikin koda, kuma ya kamata a rage kashi na farko da tabbatarwa, saboda akwai haɗarin hauhawar jini.

Allunan ya kamata a sha kafin abinci. Idan kashi na yau da kullun ya ƙunshi Allunan 1-2, ana shan kullun sau ɗaya a rana - da safe, kafin karin kumallo. Ya kamata a rarraba allurai mafi girma zuwa allurai biyu - safe da maraice.

Idan mai haƙuri saboda wasu dalilai ya rasa kashi na gaba, kuna buƙatar sha kwaya a lokacin da aka saba. A sha sau biyu an haramta!

Side effects

Dangane da sake duba marasa lafiya, Maninil na iya samun sakamako masu illa, kamar:

• Hauhawar jini, yunwar, bacci, tachycardia, rauni, rashin daidaituwa game da motsi, ciwon kai, gumi na fata, rawar jiki, tsoro, janar gaba daya, rikicewar jijiyoyin zuciya, karuwar nauyi (daga bangaren metabolism),
• Ciwon ciki, bugu, jin nauyi a cikin ciki, ciwon ciki, amai, dandano na ƙarfe a bakin, zawo (daga tsarin narkewa),
• Cutar hepatitis, choraasis intrahepatic, haɓaka ɗan lokaci na ayyukan hanta enzymes na hanta (daga ƙwayar hanta da hanta),
• Itching, petechiae, urticaria, photoensitization, vasculitis rashin lafiyan, purpura, tashin hankali anaphylactic, haɓaka halayen ƙwayar cuta, tare da zazzabi, ƙonewar fata, proteinuria, arthralgia da jaundice (daga tsarin rigakafi),
• Thrombocytopenia, pancytopenia, agranulocytosis, leukopenia, hemolytic anemia, erythropenia (daga tsarin jini).

Bugu da kari, Maninil na iya haifar da karuwar diuresis, hargitsi na gani, rikicewar masauki, hyponatremia, protein din na yau da kullun, rashin lafiyan ga probenecis, sulfonamides, abubuwan da ake amfani da su na sulfonylurea da shirye-shiryen diuretic wadanda ke dauke da rukunin sulfonamide a cikin kwayar.