Lozap 100 da

Lozap yana samuwa a cikin nau'i na allunan convex a garesu a cikin farin fim ɗin fim. Samfurin an yi nufin sarrafa shi ne na baka. Kunsasshen a cikin blister don Allunan 10 kuma cushe a fakitoci na 30, 60, 90 guda. Abun kowane kwamfutar hannu ya hada da:

• potassium losartan (abu mai aiki),
• microcrystalline cellulose,
• povidone
• magnesium stearate,
• makarin sodium,
• sabbinne,
• macrogol
• mannitol
• dimethicone
• foda talcum
• launin shuɗi.

Kasuwancin magunguna na zamani suna ba da nau'i biyu na wannan magani: Lozap da Lozap da. Zabi na farko ya ƙunshi kawai kayan aiki - losartan. Abu ne wanda ke canza enzyme (ACE) inhibitor. Additionalarin ƙarin na biyu wanda ke haɓaka tasirin potassium losartan shine hydrochlorothiazide. Yana cire wuce haddi, wanda shima yana taimakawa rage matsi. Don lura da hauhawar jini, musamman siffofi masu tsauri, an fi so a yi amfani da magunguna masu haɗuwa, tunda suna da tasiri mai ƙarfi.

A cikin kantin magani zaku iya siyan allunan don matsa lamba Lozap a yawancin magunguna: 12.5 mg, 50 da 100. Lozap da ƙari kawai a cikin - 50 MG na potassium losartan da 12.5 MG na hydrochlorothiazide.

Aikin magunguna

Lozap yadda yakamata yana rage karfin jini, rage nauyi akan tsoka. Ana ba da wannan kadarar ta miyagun ƙwayoyi ta ikonta na hana ayyukan ACE, wanda ke taimakawa sauya angiotensin-I zuwa angiotensin-II.

A sakamakon haka, wani abu wanda yake da tasiri sosai ga aikin vasoconstriction, kuma a sakamakon haka, haɓakar hawan jini, angiotensin-II, gaba ɗaya yana dakatar da ƙirƙirar cikin jiki. Sai kawai lokacin da aka katange wannan kwaron zai iya raguwa sosai a cikin karfin jini kuma zai yiwu.

Ayyukan miyagun ƙwayoyi yana farawa a cikin awa daya bayan farawa na kwamfutar hannu ta farko kuma ya kasance har zuwa kwana guda. Ana samun sakamako mafi girman akasin tushen tsarin kulawa da kwayoyi na yau da kullun. Matsakaicin karatun shine makonni 4-5. Yana yiwuwa a yi amfani da Lozap a cikin tsofaffi da matasa, musamman tare da haɓakar hauhawar jijiya mai ƙonewa.

Sakamakon yaduwar jijiyoyin jini, ya zama mafi sauƙi ga ƙwaƙwalwar zuciya don tura jini ta wurin su. Sakamakon haka, juriya ga tashin hankali ta jiki da damuwa yana ƙaruwa sosai, wanda ke sauƙaƙe yanayin marasa lafiya da ke fama da cututtukan zuciya na kullum. Bugu da kari, maganin don matsa lamba Lozap yana kara samarda jini ga zuciya, inganta hawan jini a cikin kodan, don haka za'a iya amfani dashi don nephropathy na ciwon sukari etiology da kuma gazawar zuciya.

An haɗa Lozap daidai tare da wasu kwayoyi don rage matsa lamba. Sakamakon matsakaicin tasirin diuretic din sa, yana taimakawa wajen cire wuce haddi daga jiki. Lozap da Allunan suna da tasiri sosai, tunda hydrochlorothiazide da ke cikin abun da ke ciki yana haɓaka tasirin cutar ta losartan.

Additionalarin da ainihin mahimman kayan magani shine ikonta na cire uric acid daga jikin mutum da rage haɗuwa da jini. A ƙarshen liyafar, raunin "cirewa" ba ya haɓaka.

Magunguna da magunguna

Losartan takamaiman mai karɓa ne na angiotensin II. Yana rage juriya a cikin tasoshin, yana taimakawa rage aldosterone da adrenaline a cikin jini. Akwai daidaituwa na matsin lamba a cikin jijiyoyin mahaifa, kazalika da alamu masu nuna karfin jini. Tare da amfani na yau da kullun, Lozap yana hana farin ciki na myocardium, yana ƙaruwa juriya daga zuciya zuwa ƙoƙarin jiki.

Bayan aikace-aikacen guda ɗaya, tasirin maganin ya kai kololuwa bayan sa'o'i 6, sannan sannu a hankali ragewa ya tsaya bayan sa'o'i 24. Matsakaicin sakamako mai lalacewa yana faruwa bayan kimanin makonni 3-5 na gudanarwa na gaskiya.

Losartan yana da sauri cikin tsarin gastrointestinal. Tsarin rayuwarta kusan kashi 33% ne; yana danganta garkuwar jini da kashi 99%. Matsakaicin adadinta a cikin jijiyoyin jini ya samu ne bayan sa'o'i 3-4. Yawan shaye maganin ba ya canzawa kafin abinci ko bayan abinci.

Lokacin ɗaukar ƙwayar losartan, kusan 5% ana cire shi ta kodan ta hanyar da ba a canza ba kuma dan kadan fiye da 5% a cikin yanayin metabolite mai aiki. A cikin lokuta masu tsanani na cirrhosis na giya, maida hankali kan abu mai aiki ya zama sau 5 sama da mutane masu lafiya, kuma metabolite mai aiki shine sau 17.

Alamu ga wanda za a nada

Ana amfani da miyagun ƙwayoyi azaman magani mai zaman kanta, kuma a zaman wani ɓangaren ɓangaren maganin warkarwa. An tsara shi don magance yanayin da cututtuka masu zuwa:

• hauhawar jini
• bugun zuciya (a matsayin karin kayan aiki),
• masu ciwon sukari nephropathy a cikin marasa lafiya da ciwon sukari mellitus,
• don rage hadarin kamuwa da cututtukan zuciya.

Contraindications

Yin amfani da Lozap an contraindicated idan akwai wani hyperkalemia, ciki, da kuma lactation. Ba a wajabta magani ba ga yara 'yan ƙasa da shekara 18, tunda ba a kafa lafiyarsa da ingancinsa ba. Har ila yau, maganin hana haihuwa yana sanya damuwa ga abubuwan da ke tattare da miyagun ƙwayoyi ko rashin haƙuri. Ana amfani da Lozap tare da taka tsantsan a cikin renal ko gazawar hanta, jijiyoyin jini, ko zazzaɓi.

Umarnin don amfani

Daya daga cikin fa'idodin Lozap shine yawan amfani - lokaci 1 a rana. An tsara shi ba tare da cin abinci ba. Matsakaicin ma'aunin yau da kullun don hauhawar jini shine 50 MG. Idan ya cancanta, ana iya haɓaka zuwa 100 MG cikin allurai ɗaya ko biyu. Idan an wajabta magunguna ga marasa lafiya waɗanda ke ɗaukar babban diure, to kashi na farko na Lozap ya zama bai wuce 25 MG kowace rana ba.

Umarnin don yin amfani da Lozap yana nuna cewa tare da lalacewar zuciya, ana ɗaukar maganin daga 12.5 MG, sannan a hankali ana ƙaruwa da ƙwayar cuta (lura da tsaka-tsakin mako) zuwa matsakaiciyar goyon baya na 50 MG. A cikin marasa lafiya masu fama da hanta, koda ko dialysis, kashi na farko ya kamata kuma a rage.

MUHIMMI ZAI KYAUTA! Babu sauran nessarancin numfashi, ciwon kai, raunin matsin lamba da sauran alamun HYPERTENSION! Gano hanyar da masu karatunmu suke amfani da su don magance matsin lamba. Koyi hanya.

Me ya sa kuma ba za a iya amfani da allunan Lozap ba? Suna da tasiri idan ya zama dole don rage haɗarin kamuwa da cutar zuciya da mutuwa a cikin masu cutar hawan jini. Don gyara irin waɗannan halayen, an wajabta shan kwayar 50 a kowace rana. Idan ba a cimma matakin ƙarfin jini ba, to ana buƙatar canjin kashi da ƙari na hydrochlorothiazide.

Dole ne likita ya zaɓi kashi na maganin, tunda kawai yasan wane irin matsin lamba ne kuma a cikin wane adadin Lozap ya fi tasiri. Canji mai zaman kansa a sashi na iya haifar da mummunan sakamako.

Side effects

A lokuta da yawa, ana iya jure da sinadarin losartan. Abubuwan da ke haifar da rauni ba sa faruwa, suna wucewa da sauri, ba sa buƙatar dakatar da magani. Abubuwa marasa kyau waɗanda ke faruwa a cikin ƙasa da 1% na lokuta ba su da alaƙa da ɗaukar Lozap.

Daga gefen tsarin juyayi na tsakiya, haɓakar rashin tsoro, yanayin asthenic, ƙara yawan gajiya, rashin damuwa, da damuwa na bacci mai yiwuwa ne. Wasu lokuta akwai parasthesia daban-daban, rawar jiki, tinnitus, raunin damuwa. A cikin lokuta mafi wuya, raunin gani, conjunctivitis, ciwon kai na migraine an lura.

Tsarin numfashi na iya amsawa ga miyagun ƙwayoyi ta hanyar abin da ya faru na ambaliyar hanci, bushe tari, haɓakar rhinitis, mashako na karancin numfashi.

Daga cikin tsarin gastrointestinal: tashin zuciya, amai, gudawa, gudawa, rashin jin daɗi, haɓakar acid na ruwan ciki, maƙarƙashiya. Hakanan, lokacin shan magungunan, bayyanar take hakkin tsarin zuciya: tachycardia, arrhythmia, bradycardia, angina pectoris.

Sakamakon sakamako wanda ya faru akan ɓangaren fata, tsarin kwayoyin halitta da tsarin jijiyoyin jiki suna faruwa a cikin ƙasa da 1% na lokuta.

Yawan abin sama da ya kamata

Tare da yin amfani da wuce kima ta amfani da miyagun ƙwayoyi Lozap, raguwa mai yawa a cikin karfin jini, haɓakar tachycardia mai yiwuwa ne. Game da haɗari na gudanar da babban allurai na miyagun ƙwayoyi, ana tallafawa maganin cututtukan cututtukan mahaifa. Tabbatar da inganta motsawa, lavage na ciki, tilasta diuresis.

Mahimmanci: Hemodialysis baya iya cire potassium losartan da metabolite mai aiki daga jiki.

Yin hulɗa tare da wasu magunguna

Wataƙila amfani da Lozap a hade tare da sauran magungunan antihypertensive. A lokaci guda, aikinsu yana ƙaruwa. Ba a lura da ma'amala tsakanin losartan tare da digoxidine, phenobarbital, anticoagulants, cimetidine da hydrochlorothiazide. Flucanazole da rifampicin zasu iya rage matakin metabolite mai aiki, duk da haka, canje-canje na asibiti sakamakon wannan hulɗar ba'a yi binciken su ba.

Tare da alƙawarin Lozap a hade tare da daskararren ƙwayoyin potassium, ci gaban hyperkalemia mai yiwuwa ne. Ingantaccen tasirin losartan, kamar sauran magungunan antihypertensive, za'a iya rage shi tare da indomethacin.

Yi amfani da ƙuruciya da tsufa

Ba a amfani da Lozap a cikin yara 'yan ƙasa da shekara 18, tunda ba a gwada shi ba saboda ingancinsa da amincinsa. Sigar farko don marasa lafiya tsofaffi kada su kasance sama da 50 MG. A wannan yanayin, ya kamata a gudanar da magani a karkashin kulawa na likita koyaushe kuma tare da gwaji na yau da kullun. Idan miyagun ƙwayoyi basu da tasiri, ana buƙatar daidaita sashi ko musanyawa.

Lozap da ciki

Yin amfani da miyagun ƙwayoyi ba da shawarar a farkon watanni uku na ciki, kuma yana contraindicated a wani kwanan wata. Bayanan da aka samo yayin nazarin abubuwan da ke hana waɗanda ke hana ACE a tayin cikin watanni ukun farko na haɓakawa ba su da tabbaci, amma ba a cire haɗarin gaba ɗaya ba.

Amintaccen abu ne sananne cewa yin amfani da potassium losartan a cikin na biyu, na ukku na ciki na ciki yana da mummunar illa ga tayi. Akwai raguwa a cikin aikin koda, raguwa a cikin ci gaban ƙasusuwa na kwanyar. Saboda haka, lokacin da aka tabbatar da daukar ciki, ana dakatar da shan sinadarin a losartan cikin gaggawa, kuma an wajabta mai haƙuri wani, mafi sauƙin hanyar warkewa.

Babu wani bayani game da sanya Lozap cikin nono. Don haka, mata masu shayarwa suma su guji shan wannan magani. Idan akwai wata bukatar yin amfani da wannan maganin musamman lokacin shayarwa, ya kamata a daina shayar da jarirai nono.

Umarni na musamman

Baya ga haɗuwa da Lozap tare da sauran magungunan antihypertensive, ana iya haɗe da gudanarwarsa tare da insulin da magungunan hypoglycemic (Gliclazide, Metformin da sauransu). Idan mai haƙuri yana da tarihin cutar Quincke, ƙoshin lafiya na likita ya zama dole a yayin gudanar da ayyukan losartan. Wannan ya wajaba don kawar da haɗarin yiwuwar sake komawawar rashin lafiyar.

Idan jiki yana da ƙarancin ƙwayar ruwa, wanda zai iya haifar da shi ta hanyar rashin abinci mai gishiri, zawo, amai mara amfani, ko kayan maye wanda ba a sarrafa shi ba, to shan maganin zai iya haifar da raguwa sosai cikin hawan jini (hauhawar jini). Kafin amfani da Lozap, ana bada shawara don dawo da ma'aunin ruwa-mai wari a jiki ko don amfani da miyagun ƙwayoyi a cikin ƙaramin sashi.

Lokacin da aka tsara magunguna ga marasa lafiya da ke fama da rauni na aikin ƙirar, bugun zuciya ko ciwon sukari mellitus, ya zama dole a saka idanu akan matakin creatinine da potassium a yayin duk jiyya, tunda haɗarin haɓakar haɓaka hyperkalemia yana da matukar girma. Tunda cutar koda ko stenosis na koda na katako kuma na iya haifar da haɓaka gazawar koda, ya kamata a yi amfani da losartan tare da taka tsantsan.

Kada ku ɗauki Lozap tare da sauran masu hana ACE, alal misali, Enalopril da Captopril. A bangon baya da amfani da maganin sa barci na gaba daya, ci gaban haihuwar yana yiwuwa.

Tasiri kan iya tuki motocin

Tun lokacin da ake amfani da sinadarin losartan na iya haifar da yawan fushi da fitsari, saboda haka an bada shawarar yin watsi da duk wasu ayyukan da suke bukatar maida hankali kan asalin shan irin wadannan kwayoyi. Ciki har da tuki.

Kamfanonin magunguna na zamani suna ba da alamun analogues na Lozap da yawa daga masana'antanta daban-daban. Daga cikin su, zaku iya samun magunguna masu tsada ko rahusa. Magungunan da ake tambaya da kwayar cutar ta analogues na iya samun sakamako daban, sabili da haka, lokacin zabar sa, ya kamata ka fara tuntuɓar likitanka.

Daga cikin misalai na zamani na Lozap, mafi yawan su ne:

Duk waɗannan magunguna suna da alamomi iri ɗaya da contraindications don amfani, sun bambanta kawai a sashi, farashi da mai ƙira.

Mahimmanci: Ba a tsara magungunan don lokuta masu tsanani na hauhawar jini ba. A irin waɗannan halayen, ana buƙatar alƙawarin hadadden ilimin jiyya.

Lorista da Lozap - wanda yafi kyau

Sinadaran da ke aiki a cikin magunguna iri daya ne. An wajabta su ga marasa lafiya da hauhawar jini da raunin zuciya. Koyaya, farashin Lorista umarni ne mai girma ƙasa da na Lozap. Za'a iya siyan farkon a cikin 130 rubles don allunan 30, na biyu don 280 rubles.

Kowane magani yana da nasa abubuwan ci gaba. Reviews game da miyagun ƙwayoyi Lozap ba gaba daya ma'ana. Yawancin marasa lafiya suna magana game da tasiri na miyagun ƙwayoyi. Yana da sauri daidaita matsin lamba, inganta haɓaka lafiyar marasa lafiya da sauri. Koyaya, ƙwayar ba ta taimaka wa kowa. An lura da raunin wadannan Lozap:

• bayan sun sha magani wanda ke dauke da sinadarin losartan, marasa lafiya suna bushe tari,
• gaban tachycardia aka rubuta,
• tinnitus
• wasu nau'in hauhawar jini suna buƙatar fiye da kashi ɗaya,
• akwai lokuta na rashin sakamako mai mahimmanci, wanda ya buƙaci daidaita sashi ko maye gurbin miyagun ƙwayoyi,
• ci gaban jaraba mai yiwuwa ne.

Aorafin ƙarshe game da tasiri na miyagun ƙwayoyi, za'a iya lura cewa bai dace da kowa ba. Abin da ya sa dole ne a gudanar da zaɓin magungunan rigakafin tare tare da likitan halartar. Bai kamata ku zaɓi irin waɗannan magunguna da kanku ba, saboda maimakon amfanin da ake tsammanin, zaku iya cutar da jikinku kawai.

Farashin kimantawa a Rasha

Ya danganta da girman kunshin na Lozap, sashi, gwargwadon masana'anta, farashinsa na iya bambanta tsakanin 230-300 rubles a kowane fakitin. Ya kamata a zaɓi ƙarancin analogues mai rahusa tare da likita kawai.

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Ajiye mata!

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Form sashi.

Allunan mai rufe fim.

Abubuwan da aka yi amfani da su na asali da na kimiyyar sunadarai: Allunan launin rawaya mai launin rawaya, mai ɗaukar hoto, tare da daraja a garesu.

Kungiyar magunguna. Shirye-shiryen haɗin gwiwar angiotensin II inhibitors. Masu adawa da rashin lafiyar Angiotensin II da na diuretics. Lambar ATX ta C09D A01.

Kayan magunguna

Lozap® 100 Plus haɗuwa ne na losartan da hydrochlorothiazide.Abubuwan da ke tattare da miyagun ƙwayoyi suna nuna sakamako mai tasiri na antihypertensive, rage girman matakin hawan jini zuwa mafi girma fiye da kowane ɗayan kayan aikin daban-daban. Sakamakon sakamako na diuretic, hydrochlorothiazide yana ƙara yawan aikin renin plasma (ARP), yana ƙarfafa ɓoyewar aldosterone, yana ƙara matakin angiotensin II kuma yana rage matakin potassium a cikin ƙwayar jini. Amincewa da losartan yana toshe duk cututtukan ilimin halittar jiki na angiotensin II kuma, saboda hanawar tasirin aldosterone, yana taimakawa rage asarar potassium da ke da alaƙa da amfani da diuretics.

Losartan yana da tasiri na matsakaici na uricosuric, yana wucewa idan an dakatar da maganin.

Hydrochlorothiazide dan kadan yana haɓaka matakin uric acid a cikin jini; haɗuwar losartan da hydrochlorothiazide yana raunana hyperuricemia wanda ke haifar da diuretic.

Losartan shine mai karɓar angiotensin II na roba mai rikicewa (nau'in masu karɓar AT 1) don amfani da baka.

Lokacin amfani da losartan, ƙin mummunan sakamako na rashin damuwa na angiotensin II akan rikodin renin yana haifar da karuwa a cikin aikin renon plasma (ARP). Anaruwar ARP yana haifar da karuwa a cikin taro na angiotensin II a cikin jini. Duk da karuwa da yawaitar waɗannan abubuwan, aikin antihypertensive da raguwa a cikin taro na aldosterone a cikin ƙwayar jini yana ci gaba, wanda ke nuna ingantaccen toshewar masu karɓar angiotensin II. Bayan dakatar da losartan, ƙimar ARP da angiotensin II yana raguwa zuwa matakin farko a cikin kwanaki uku.

Dukansu losartan da babban aikin metabolite suna da kusanci sosai ga masu karɓar AO 1 fiye da masu karɓar AO 2. Metabolite mai aiki shine sau 10-40 fiye da aiki fiye da losartan, lokacin da aka ƙididdige shi akan nauyin jikin mutum.

Dangane da binciken da aka tsara musamman don kimanta abin da ya faru na tari a cikin marasa lafiya da ke ɗaukar losartan, idan aka kwatanta da marasa lafiya da ke karɓar inhibitors na ACE, abin da ya faru na tari a cikin marasa lafiya da ke ɗaukar losartan ko hydrochlorothiazide kusan iri ɗaya ne kuma a lokaci guda, ƙididdigar ƙididdigar ƙwaƙwalwa ta fi girma. a cikin marasa lafiya suna shan inhibitors na ACE.

Amfani da sinadarin losartan a cikin marassa lafiya ba tare da cutar sankarar mahaifa ba da kuma fama da hauhawar jini tare da proteinuria yana rage matakin proteinuria, haka kuma ragewar albumin da IgG immunoglobulin ta hanyar kimanta.