Allunan Gliformin: alamomi don amfani, tasirin sakamako da kuma alamun ƙwayar cuta

Wakilin hypoglycemic na baka daga rukunin biguanide.
Shiri: GLYFORMIN®
Aiki mai guba na miyagun ƙwayoyi: metformin
Lullukin ATX: A10BA02
KFG: Magungunan maganin ƙwaƙwalwa na baka
Lambar yin rijista: P No. 003192/01
Ranar rajista: 04/21/04
Mai mallaka reg. doc.: Tsarin kemikal da magunguna AKRIKHIN OJSC

Formaddamar da tsari da abun da ke ciki

Hanyar sashi na Gliformin shine Allunan.

Abubuwan da ke aiki da maganin shine metformin hydrochloride. Concentarfafawarsa a cikin kwamfutar hannu ɗaya na iya zama 500 MG, 850 MG ko 1 gram.

Abubuwan taimako na allunan 500 MG sune alli phosphate dihydrate, sorbitol, povidone (polyvinylpyrrolidone), stearic acid ko alli stearate, macrogol (polyethylene glycol). Ana sayar da guda 60. a cikin kwali na kwali (fakitoci 6 da ke kunshe cikin Allunan 10).

Componentsarin abubuwan haɗin Glyformin 850 MG da allunan gram 1 sune sitaci dankalin turawa, stearic acid, povidone (polyvinylpyrrolidone). A waɗannan allurai, ana sayar da allunan 60. a cikin gwangwani na polypropylene.

Pharmacodynamics

Metformin magani ne na baki wanda yake na sashen biguanides. Yana rage alamun bayyanuwa, kuma an rage girman haɗarin haɓakar hypoglycemia. Ba kamar abubuwan da ake amfani da su na sulfonylurea, sinadarin ba ya motsa samar da insulin kuma ba a kwatanta shi da tasirin hypoglycemic lokacin amfani da masu sa kai na lafiya.

Metformin yana ƙaruwa da hankalin masu karɓa na ƙasa zuwa insulin da haɓaka amfani da glucose a cikin ƙwayoyin, kuma yana hana gluconeogenesis a cikin hanta kuma yana hana shaye-shaye na carbohydrates a cikin hanji. Metformin yana kunna samar da glycogen ta hanyar yin aiki da glycogen synthase kuma yana ƙaruwa da karfin jigilar kowane nau'ikan jigilar glucose na jiki.

Glyformin kuma yana da tasiri sosai a kan rage yawan ƙwayoyin cutar lipid, rage yawan ƙwayar triglycerides, ƙarancin lipoproteins mai yawa da kuma yawan ƙwayoyin cuta. A bangon baya na jiyya tare da metformin, nauyin jikin mai haƙuri yana kasancewa ko sauyawa, ko an rage shi da kadan.

Pharmacokinetics

Bayan gudanar da baki, ana amfani da metformin daga ƙwayar narkewa sosai. Cikakken bayanin halittunsa ya kai kashi 50-60%. Matsakaicin mafi kyawun abu a cikin plasma an kai shi kimanin awa 2.5 bayan gudanarwa kuma shine 15 μmol, ko 2 /g / ml. Lokacin shan metformin tare da abinci, shanshi ya ragu kuma yana raguwa. An rarraba shi cikin sauri a cikin tsokoki na jikin mutum, kusan ba a ɗaura shi da sunadaran plasma.

Metformin yana metabolized sosai kadan kuma an keɓance shi a cikin fitsari. Cire shi cikin masu ba da agaji na lafiya shine 400 ml / min (wanda shine sau 4 sama da izinin Allah), wanda ke tabbatar da kasancewar tsananin ɓoyewar tubular. Rabin rayuwar shine kimanin awanni 6.5. Tare da gazawar koda, yana ƙaruwa, wanda ke haifar da haɗarin tarin ƙwayoyi.

Alamu don amfani

An wajabta Gliformin a cikin lura da:

• Type II ciwon sukari mellitus, lokacin da kwayoyi basu da tasiri sulfonylureas damaganin rage cin abinci,
• nau'in ciwon sukari a matsayin ban da insulin far.

Contraindications

Ba da shawarar shan wannan magani tare da:

• masu fama da cutar sankara da yanayin farko
• katoacidosis,
• cututtuka
• raunuka na hanta da kodan,
• na zuciya ko jijiyoyin jini,
• m yawaitar infarction,
• lactation, ciki.

Umarnin don amfani da Gliformin (Hanyar da sashi)

Kamar yadda aka nuna ta hanyar amfani da Gliformin, ana ɗaukar allunan a baki. A wannan yanayin, kwanakin 3 na farko, ana wajabta masu haƙuri 500 zuwa ga allurai guda ɗaya yayin rana, lokaci guda ko bayan abinci. Sannan sannu a hankali ana ƙaruwa zuwa 1 g. Yawancin lokaci, ana tabbatar da sigar yau da kullun shine 0.1-0.2 g.

Yawan abin sama da ya kamata

A cikin lokuta na yawan abin sama da ya kamata na iya faruwa lactic acidosism. Babban dalilin ci gaban shi shine tarawa. metformin saboda lalacewar aikin na haya. A wani matakin farko ya bayyana: tashin zuciya, amai, zawo, rauni gaba daya, rage zafin jiki, zafin ciki da kasala, rage karfin jiki, bradyarrhythmia. Sai numfashi da sauritsananin farin cikimai rauni da hankali harma da ci gaba coma.

Lokacin da bayyanar cututtuka ta bayyana lactic acidosis dole ne nan da nan ka daina shan Gliformin. Ana yin ƙarin aikin tiyata a asibiti, don haka mai haƙuri yana buƙatar asibiti, yana buɗe taro na lactate, yana tabbatar da ganewar asali. Hanyoyi masu amfani maganin hemodialysistaimaka cirewa daga jiki lactate da metformin. Hakanan ana yin ƙarin magani na alama.

Tsarin saki na Glyformin, marufi na kwayoyi da abun da ke ciki.

Allunan fararen fata ne ko kuma fararen fata, silsila-silin, tare da bevel da daraja.

Shafin 1
metformin (a cikin nau'in hydrochloride)
250 MG
-«-
500 MG

Fitattun mahaɗan: sorbitol, alli phosphate dihydrate, polyvinylpyrrolidone (povidone), polyethylene glycol (macrogol), alli stearate ko acid stearic.

10 inji mai kwakwalwa. - fakiti mai bakin ciki (3) - fakitoci na kwali.
10 inji mai kwakwalwa. - fakitin bakin (6) - fakitoci na kwali.
10 inji mai kwakwalwa. - fakiti mai bakin ciki (10) - fakitoci na kwali.
60 inji mai kwakwalwa. - gwangwani gilashin duhu (1) - fakitoci na kwali.
Guda 100 - gwangwani gilashin duhu (1) - fakitoci na kwali.

LITTAFIN SAURARON SAUKI.
Duk bayanan da aka bayar an gabatar dasu ne kawai don fahimtar tare da miyagun ƙwayoyi, ya kamata ka nemi likita game da yiwuwar amfani.

Maganin magunguna na glyformin

Wakili hypoglycemic wakili daga rukuni na biguanides (dimethylbiguanide). Hanyar aiwatar da metformin yana da alaƙa da iyawarta don dakatar da gluconeogenesis, kazalika da samuwar ƙwayoyin mai mai kyauta da hadawar hada hada abubuwa da hada abubuwa da abubuwa na kitse. Metformin baya tasiri da yawan insulin a cikin jini, amma yana canza magunguna ta hanyar rage ragin insulin da za'a ɗauka kyauta da kuma ƙara yawan rabo daga insulin zuwa proinsulin. Haɗi mai mahimmanci a cikin tsarin aikin metformin shine ƙarfafa motsa jini daga ƙwayoyin tsoka.

Metformin yana haɓaka wurare dabam dabam na jini a cikin hanta kuma yana haɓaka juyar da glucose zuwa glycogen. Yana rage matakin triglycerides, LDL, VLDL. Metformin yana haɓaka ƙirar fibrinolytic ta jini ta hanyar dakatar da nau'in mai kunnawa mai hana jini plasminogen.

Sashi da hanyar gudanar da magani.

Ga marasa lafiya da basa karbar insulin, a cikin kwanakin 3 na farko - 500 mg sau 3 / rana ko 1 g 2 sau / rana yayin ko bayan abinci. Daga rana ta 4 zuwa rana ta 14 - 1 g sau 3 / rana. Bayan rana ta 15, ana daidaita sashin shan la'akari da matakin glucose a cikin jini da fitsari. Adadin kulawa shine 100-200 mg / rana.

Tare da yin amfani da insulin a lokaci daya a cikin ƙarancin ƙasa da raka'a 40 / rana, tsarin kulawa na metformin iri ɗaya ne, yayin da za a iya rage yawan insulin a hankali (ta hanyar raka'a 4-8 a kowace rana). Idan mai haƙuri ya sami fiye da raka'a 40 / rana, to, yin amfani da metformin da raguwa a cikin adadin insulin yana buƙatar kulawa sosai kuma ana gudanar da shi a asibiti.

Sakamakon sakamako na glyformin:

Daga tsarin narkewa: mai yiwuwa (galibi a farkon jiyya) tashin zuciya, amai, zawo.

Daga tsarin endocrine: hypoglycemia (galibi lokacin da aka yi amfani dashi a cikin allurai marasa inganci).

Daga gefen metabolism: a wasu yanayi - lactic acidosis (yana buƙatar dakatarwa da magani).

Daga tsarin hemopoietic: a wasu yanayi - megaloblastic anemia.

Contraindications wa miyagun ƙwayoyi:

Laifi mai yawa na hanta da kodan, bugun zuciya da gazawar numfashi, lokaci mai tsaiko na myocardial infarction, buguwa mai taushi, cutar sankara, ketoacidosis, lactic acidosis (gami da tarihi), cutar ciwon suga, ciwon ciki, lactation, laushi ga metformin.

FASAHA DA LITTAFINSA
Contraindicated a cikin ciki da kuma lactation.

Umarnin na musamman don amfanin glyformin.

Ba'a bada shawara ga cututtukan m, daɗaɗɗar cututtukan cututtukan fata da cututtukan kumburi, raunin da ya faru, cututtukan tiyata, da haɗarin rashin ruwa.

Kada ayi amfani dasu kafin aikin tiyata kuma cikin kwanaki 2 bayan an yi su.

Ba'a ba da shawarar yin amfani da metformin a cikin marasa lafiya fiye da shekaru 60 da waɗanda ke yin aiki na zahiri, wanda ke da alaƙa da haɓakar haɓakar lactic acidosis.

A lokacin jiyya, ya zama dole don saka idanu akan aikin renal, ya kamata a aiwatar da ƙuduri na abubuwan lactate a cikin plasma aƙalla sau 2 a shekara, kuma tare da bayyanar myalgia.

Za'a iya amfani da Metformin a hade tare da sulfonylureas. A wannan yanayin, musamman saka idanu na matakan glucose na jini ya zama dole.

Yin amfani da metformin a matsayin wani ɓangare na maganin haɗin gwiwa tare da insulin ana bada shawarar a asibiti.

Yin hulɗa tare da Gliformin tare da wasu kwayoyi.

Tare da yin amfani da lokaci guda tare da abubuwan da aka samo na sulfonylurea, acarbose, insulin, salicylates, MAO inhibitors, oxygentetracycline, ACE inhibitors, tare da clofibrate, cyclophosphamide, tasirin hypoglycemic na metformin na iya inganta.

Tare da yin amfani da lokaci guda tare da GCS, hana rigakafin hormonal don sarrafawa na baka, adrenaline, glucagon, hormones thyroid, abubuwan da ke tattare da kwayoyin halittar thiazide, abubuwan da aka samo na nicotinic acid, raguwar tasirin hypoglycemic na metformin mai yiwuwa ne.

Amfani da cimetidine na iya ƙara haɗarin lactic acidosis.

Umarnin don amfani da Gliformin: hanya da sashi

Ana ɗaukar allunan Glyformin a baki yayin abinci ko kuma nan da nan bayan, ba tare da tauna ba, tare da ruwa mai yawa.

Likita ya ba da umarnin sashi da lokacin gudanarwa daban-daban, tare da yin la’akari da matakin yawan tattarawar glucose a cikin jini.

A farkon jiyya, kwanakin farko na 10-15, kashi na iya zama daga 0.5 zuwa 1 g sau ɗaya a rana, to, ya danganta da matakin sukari a cikin jini, sannu a hankali ana iya ƙaruwa. Adadin kiyayewa, a matsayin mai mulkin, shine 1.5-2 g kowace rana, an kasu kashi 2-3.

Matsakaicin maganin yau da kullun na Gliformin shine 3 g.

Ga tsofaffi marasa lafiya, matsakaicin adadin izinin magani shine 1 g kowace rana.

Game da rikice-rikice na rayuwa na rayuwa, ana bada shawarar rage kashi, tunda haɗarin lactic acidosis yana ƙaruwa.

Side effects

• Daga tsarin endocrine: idan akwai batun yawan zubar jini - hypoglycemia,
• Daga tsarin narkewa: rashin ci, zafin ciki, tashin zuciya, dandano mai ƙarfe a bakin, zawo, amai, ƙwanƙwasawa (waɗannan alamun halayen ne na fara magani, sannan yanayin ya zama al'ada),
• Daga tsarin hawan jini: wani lokacin - megaloblastic anemia,
• Daga gefen metabolism: tare da tsawan magani - hypovitaminosis B₁₂, a cikin mafi yawan lokuta, lactic acidosis,
• Allergic halayen: fatar fata.

Idan sakamako masu illa sun faru, ya zama dole a soke Glyformin na ɗan lokaci kuma a nemi likita.

Umarni na musamman

Yakamata a kula da kula da matakan glucose na yau da kullun.

Yayin lokacin jiyya, ya kamata a gudanar da karatun kowane wata shida don sanin matakin lactate da creatinine a cikin jini. Ana lura da aikin koda musamman a cikin tsofaffi marasa lafiya. Bai kamata a rubanya Glyformin ga maza da ƙirar creatinine sama da 135 μmol / L ba, ga mata - 110 μmol / L.

Ana iya rage tasirin sakamako daga tsarin narkewa ta hanyar amfani da antacids ko maganin antispasmodics na lokaci daya.

A lokacin jiyya ya kamata ya daina shan barasa da kayayyakin da ke ɗauke da ethanol.

Tare da monotherapy, Gliformin ba ya tasiri da ikon fitar da motoci da aiki tare da kayan aiki.

Yayin ɗaukar Gliformin tare da sauran wakilai na hypoglycemic, ciki har da insulin, sulfonylureas, ya zama dole a yi hankali lokacin tuki motoci da yin ayyukan haɗari masu haɗari waɗanda ke buƙatar babban saurin halayen psychomotor da karuwar hankali.

Haihuwa da lactation

Amfani da metformin yayin daukar ciki da shayarwa yana kare.

Lokacin da ake shirin yin ciki, da kuma cewa idan ya faru yayin jiyya tare da Gliformin, an soke maganin kuma an tsara maganin insulin.

Ba a tabbatar dashi daidai ba ko metformin ya shiga cikin madarar nono, don haka bai kamata a rubuta Glyformin ba lokacin shayarwa. Idan abin sha yana da mahimmanci, ya kamata a daina shayar da jariri.

Hulɗa da ƙwayoyi

Zai yiwu a haɓaka aikin Glyformin tare da yin amfani da lokaci ɗaya tare da insulin, beta-blockers, sulfonylureas, magungunan anti-mai kumburi steroidal, acarbose, monoamine oxidase inhibitors, angiotensin canza enzyme inhibitors, oxytetracycline, cyclophosphamide, da sauransu.

Sakamakon Gliformin na iya raguwa yayin amfani da glucagon, glucocorticosteroids, maganin hana haihuwa, hormones thyroid, epinephrine, sympathomimetics, "madauki" da thiazide diuretics, abubuwan asalin nicotinic acid da phenothiazine.

Amfani na ethanol wanda ke dauke da jami'ai na lokaci guda zai iya haifar da ci gaban laas acidosis.

Kawar da Glyformin yana raguwa lokacin da aka haɗu tare da cimetidine, yiwuwar haɓaka lactic acidosis yana ƙaruwa.

Tare da gudanar da sabis na lokaci daya tare da maganin anticoagulants, abubuwan coumarin, ana rage tasirin su.

Analogues na Gliformin sune: Glucofage, Glucofage Long, Glukoran, Gliguanid, Dformin, Diaberit, Diabetosan, Diabexil, Diguanil, Metformin, Melbin, Mellitin, Metiguanid, Modulan, Formmetin.

Ra'ayoyi game da Gliformin

Dangane da sake dubawa na Gliformin, yana da tasiri duka a cikin batun ciwon sukari mellitus da kuma a cikin cututtuka daban-daban na rayuwa. Hakanan, sau da yawa ana amfani da shi ta hanyar marasa lafiya da ke neman rasa nauyi, kuma wasu mutanen da suke amfani da shi don waɗannan dalilai suna da'awar cewa sun sami damar rasa nauyi kuma su daidaita matakan hormonal. Koyaya, masana da yawa sun yi gargaɗi game da amfani da Gliformin don asarar nauyi, idan babu tabbatattun alamu ga hakan.

Wasu marasa lafiya sun ambaci sakamako masu illa mara kyau na miyagun ƙwayoyi, ciki har da ciwon kai, rauni, raunin dyspeptik. Tunda yana da ikon yin amfani da tasirin gaske ko kuma mummunar illa a jikin mutum, ana bada shawarar a kula da shi sosai a ƙarƙashin kulawar likita.

Farashin Gliformin a cikin magunguna

Kimanin farashin Gliformin 0.5 g allunan a cikin sarƙoƙi na kantin magani shine 86-130 rubles (kunshin ya ƙunshi Allunan 60). Kuna iya siyan allunan a cikin fim mai rufi tare da sashi na 0.85 g na kimanin 191-217 rubles, kuma sashi na 1 g na 242-329 rubles (kowane kunshin ya ƙunshi Allunan 60).

Gliformin: farashin a cikin kantin magani na kan layi

GLYFORMIN 500mg 60 inji mai kwakwalwa. Allunan mai rufe fim

Gliformin 0.85 g allunan da aka sanya fim 60 inji mai kwakwalwa.

Ilimi: Jami'ar Kiwon lafiya ta jihar Rostov, kwararrun "General Medicine".

Bayanai game da miyagun ƙwayoyi an samar da su duka, an bayar da su don dalilai na bayanai kuma baya maye gurbin umarnin hukuma. Kai magani yana da haɗari ga lafiya!

Dangane da bincike, matan da ke shan tabarau na giya ko giya a mako guda suna da haɗarin kamuwa da cutar sankarar mama.

A cewar masana kimiyya da yawa, hadadden bitamin ba su da amfani ga mutane.

A yunƙurin fitar da mara lafiya, likitoci sukan yi nisa sosai. Don haka, alal misali, wani Charles Jensen a cikin shekarun daga 1954 zuwa 1994. ya tsira fiye da 900 aikin cirewar neoplasm.

A lokacin rayuwa, matsakaicin mutum ya samar da kasa da ruwa biyu na yau.

Mabuɗin cakulan duhu huɗu sun ƙunshi adadin kuzari ɗari biyu. Don haka idan ba kwa son samun lafiya, zai fi kyau kada ku ci fiye da lobules biyu a rana.

Dangane da kididdigar, a ranakun Litinin, hadarin raunin baya yana ƙaruwa da 25%, da kuma haɗarin bugun zuciya - da kashi 33%. Yi hankali.

Additionari ga mutane, halittu masu rai guda ɗaya a duniya - karnuka, suna fama da cutar sankara. Waɗannan ainihin abokanmu ne masu aminci.

Miliyoyin ƙwayoyin cuta ana haihuwar su, suna rayuwa kuma suna mutuwa cikin gutuwarmu. Ana iya ganin su kawai da girman girma, amma idan sun taru, za su dace da kofin kofi na yau da kullun.

Masana kimiyyar Amurka sun gudanar da gwaje-gwaje a kan mice kuma sun yanke hukuncin cewa ruwan kankana yana hana haɓakar atherosclerosis na hanyoyin jini. Groupaya daga cikin ƙungiyar mice sun sha ruwa a bayyane, ɗayan kuma ruwan 'ya'yan itace kankana. A sakamakon haka, tasoshin rukunin na biyu sun kasance ba su da matattarar cholesterol.

Lokacin da masoya suka sumbaci, kowannensu yana asarar 6.4 kcal a minti daya, amma a lokaci guda suna musayar kusan nau'ikan kwayoyin 300 daban-daban.

Mutanen da ake amfani da su don karin kumallo na yau da kullun ba su da kiba.

Jinin ɗan adam "yana gudana" ta cikin jiragen ruwa a ƙarƙashin matsanancin matsin lamba, kuma idan an keta mutuncin sa, zai iya harba har zuwa mita 10.

Matsakaicin rayuwar lefties ya kasa da nisanci.

A Burtaniya, akwai wata doka wacce a ciki wacce likitan tiyata zai iya yin aikin tiyata ga mara lafiyar idan ya sha sigari ko kuma ya wuce kiba. Yakamata mutum ya daina munanan halaye, sannan kuma, wataƙila, ba zai buƙaci sa hannun tiyata ba.

Matsayin kwakwalwar mutum kusan kashi biyu cikin ɗari ne na nauyin jiki, amma yana cin kusan kashi 20% na iskar oxygen da ke shiga jini. Wannan hujja tana sanya kwakwalwar dan Adam matsanancin rauni don lalacewa ta hanyar karancin iskar oxygen.

An san man kifi na shekaru da yawa, kuma a wannan lokacin an tabbatar da cewa yana taimakawa wajen rage kumburi, yana kawar da ciwon haɗin gwiwa, inganta haɓaka.

Sashi da gudanar da Gliformin

A matsayinka na mai mulki, likita ya saita kashi na Glyformin daban-daban, gwargwadon matakin glucose a cikin jini.

Jiyya yakan fara ne da amfani da 0.5-1 g kowace rana. Ya danganta da matakin glycemia, kashi na iya fara ƙaruwa bayan kwanaki 10-15.

Kulawa na yau da kullun shine 1-2 Allunan Gliformin 1000, wanda aka ba da shawarar a rarrabashi zuwa dawain da yawa, wanda zai iya rage tsananin tasirin sakamako wanda ya shafi lalacewa.

Matsakaicin izini na yau da kullun shine 3 allunan Gliformin 1000, duk da haka, an ba da shawarar cewa tsofaffi ba su wuce 1 g na miyagun ƙwayoyi ba.

Tare da yawan wuce haddi na Gliformin, lactic acidosis na iya haɓakawa tare da sakamako mai ƙisa, alamomin farkon waɗanda suke tashin zuciya, ƙananan zafin jiki, gaba ɗaya rauni, zawo, amai, jin zafi a cikin ciki da tsokoki, bradyarrhythmia, rage karfin jini, farin ciki, raunin hankali, ƙarancin numfashi, haɓaka ƙwayar cuta .

Sharuɗɗan da yanayin ajiya

Gliformin yana cikin adadin magunguna masu yawa na hypoglycemic (jeri B) tare da shawarar rayuwar shiryayye a cikin yanayin ajiya (a yanayin zafi har zuwa 25 ° C):

• Tare da abun ciki na 250 MG da 500 MG na kayan aiki - shekaru 3,
• Tare da abun ciki na 850 MG da 1000 MG na aiki mai aiki - shekaru 2.

Umarnin don amfani da allunan

Alamu don amfani da miyagun ƙwayoyi sune nau'in sukari na 2 na ciwon sukari, lokacin da tsayayyen abinci da kwayoyi na ƙungiyar sulfonylurea basu da tasirin da ake so. Hakanan ana wajabta Glyformin don ciwon sukari na 1 a matsayin haɗin kai don injections na insulin.

Yayin aikin, dole ne a sa ido kan aikin kodan, aƙalla a kowane watanni 6 ana bada shawara don yin bincike don tantance maganin lactate a cikin jini.

Allunan za a iya bugu lokacin abinci ko bayan abinci, ainihin sashi ya kamata a wajabta shi daban-daban daga likitan halartar, la'akari da sakamakon gwajin sukari na jini:

• a farkon far, kashi ba ya wuce gram 1 a kowace rana,
• bayan kwanaki 15, adadin kudaden yana ƙaruwa.

Daidaitaccen matakin kiyayewa bai wuce 2 grams a rana ba, dole ne a rarraba shi akan allurai da yawa. Masu ciwon sukari na tsufa na kwana ɗaya ana bada shawara don ɗaukar nauyin 1 gram na miyagun ƙwayoyi.

Idan likita ya tsara Gliformin don ciwon sukari, mai haƙuri ya kamata ya san cewa allunan na iya haifar da adadin mummunan halayen jiki. A wani ɓangare na tsarin endocrine, hauhawar jini yana haɓaka, a ɓangaren zagayen jini, anaemia mai yiwuwa ne, a wani ɓangaren raunin bitamin metabolism yana faruwa. Jiki wani lokacin yakan amsa magunguna tare da halayen rashin lafiyan:

Daga gabobin ciki na ciki akwai cin abinci, zawo, amai, dandano mai ƙarfe a cikin bakin.

Idan wani mummunan halayen ya faru, yana nuna ƙin karɓar magani tare da Gliformin, nemi likita.

Glyformin na miyagun ƙwayoyi (ana ba da umarnin sa a cikin Intanet kyauta) ana iya amfani dashi don lalacewa na matsakaici na matsakaici, amma kawai cikin rashin yiwuwar karuwa a cikin lactic acidosis. A wannan yanayin, ana lura da aikin koda koda yaushe (aƙalla sau ɗaya a kowane watanni 3-6), lokacin da keɓancewar creatinine ya ragu zuwa matakin 45 ml / min, an dakatar da magani nan da nan.

Idan an rage aikin koda a cikin masu ciwon sukari na gaba, sashi na metformin yana buƙatar gyara.

Contraindications, hulɗa da miyagun ƙwayoyi

Bai kamata a rubuta Gliformin don ketoacidosis ba, cututtukan hanta na koda, cututtukan cututtukan mahaifa, zuciya, gazawar huhun ciki, a lokacin daukar ciki, shayarwa, infarction na zuciya, yawan wuce gona da iri ga abubuwan da ke cikin miyagun ƙwayoyi.

An tsananta ɗaukar magani don cututtukan cututtukan etiology, kafin gudanar da mummunan aikin tiyata.

Tasirin maganin zai iya raguwa tare da magani na layi daya:

• magungunan glucocorticosteroid
• cututtukan mahaifa
• kamuwa da cuta
• nicotinic acid
• lokacin shan maganin hana daukar ciki.

Idan ana amfani da metformin tare da insulin, abubuwan da ake amfani da su na sulfonylurea, magungunan anti-steroidal anti-inflammatory, da kuma beta-blockers, akwai damar samun karuwa sakamakon sa.

Tsaunin Gliformin

A wasu halaye, mai haƙuri da ciwon sukari ana nuna Gliformin tsawanta - Gliformin tsawanta. Ana ɗauka ta baka da isasshen ruwan. Kayan aiki na iya taimakawa a kan kansa ko kuma zama wani ɓangare na maganin warkewa.

Idan mai ciwon sukari bai taɓa shan metformin ba, ana ba shi shawarar farko na 750 MG sau ɗaya a rana. Bayan makonni 2, likita zai daidaita sashi (ɗauki 2 Allunan na 750 MG), dangane da sakamakon gwajin sukari. Tare da jinkirin karuwa a cikin adadin ƙwayoyi, akwai raguwar halayen marasa kyau daga tsarin narkewa, musamman, zazzabin cizon sauro ya ɓace.

Lokacin da shawarar da aka ba da shawarar ba ta ba da damar cimma ikon sarrafawa na yau da kullun na glycemia, yana da mahimmanci don ɗaukar mafi yawan magunguna - 3 Allunan 750 MG Tsawon lokaci sau ɗaya a rana.

Masu ciwon sukari waɗanda ke shan metformin a cikin nau'in magani na sakewa na yau da kullun:

1. sha a tsawon daidai gwargwado,
2. idan sun dauki fiye da 2000 MG, ba a ba da izinin canzawa zuwa tsawan tsari na miyagun ƙwayoyi ba.

Don cimma iyakar sarrafa glycemic, ana amfani da metformin da insulin na hormone a matsayin magani hade. Da farko, ɗauki madaidaicin adadin magani (1 kwamfutar hannu 750 MG) a lokacin abincin dare, kuma dole ne a zaɓi adadin insulin daban-daban, gwargwadon sukari na jini.

Matsakaicin kowace rana, yana halatta a ɗauki fiye da 2250 MG na miyagun ƙwayoyi, sake dubawar likitoci sun nuna cewa, idan har yanayin jikin yana sarrafawa yadda yakamata, zai yuwu canzawa zuwa shan maganin tare da sakin tsohuwar metformin a cikin sashi na 3000 MG.

Yana faruwa da mara lafiya ya rasa shan maganin, wanda idan aka nuna shi zai ɗauki kwamfutar hannu na gaba na magani a lokacin da ya saba. Ba za ku iya ɗaukar ninki biyu na metformin ba, wannan zai haifar da ci gaban halayen da ba su da kyau, yana haifar da alamun ciwon sukari, wanda bai kamata a ƙyale shi ba.

Dole ne a dauki Glyformin Prolong a kowace rana, don guje wa hutu.

Mai haƙuri ya kamata ya sanar da likitan halartar game da dakatar da magani, gano ra'ayinsa.

Analogs, sake dubawa na likitoci

Saboda kasancewar contraindications, magungunan ba su dace da marasa lafiya da yawa ba, wanda a cikin yanayin akwai buƙatar zaɓar analogues na miyagun ƙwayoyi, sun kuma ƙunshi adadin daban-daban na kayan aiki (250, 500, 850, 1000). Gliformin na iya kasancewa tare da kwayoyi:

Masu ciwon sukari da suka riga sun yi amfani da maganin Gliformin suna nuna alama tana da yawan yuwuwar wuce haddi. A mafi yawan lokuta, wannan yana faruwa ne saboda rashin amfani da maganin.

Yawan abin sama da ya kamata na iya haifar da ci gaban irin wannan yanayin a matsayin lactic acidosis. Babban bayyanannunsa: jin zafi, amai, tashin zuciya, rashin lalacewa. Lokacin da irin waɗannan bayyanar cututtuka suka bayyana, ana bada shawara a daina shan magani.

Likitoci sun ce miyagun ƙwayoyi Gliformin zai iya maganin ciwon sikari yadda ya kamata, muddin ana lura da shawarar da aka bayar da kyau. Wani ƙari na maganin shine farashin mai ma'ana da kuma kasancewa a cikin magunguna.

Endocrinologists yayi kashedin cewa a duk tsawon lokacin da ake yin magani, ana buƙatar gwaje-gwaje na tsarin halittar creatinine. Kada a dauki magungunan Glyformin don ciwon sukari tare:

1. tare da giya sha,
2. kwayoyi masu ɗauke da ethanol.

Abin baƙin ciki, ciwon sukari ya zama cuta gama gari, kuma tsakanin matasa. Don neman magani, ya zama dole don rubanya magani wanda ke taimakawa wajen daidaita matakin glycemia, ɗayan waɗannan magungunan shine Gliformin. Idan an bi umarnin don amfani daidai, sakamakon maganin yana faruwa a cikin ɗan gajeren lokaci.

Ana ba da bayani game da magunguna masu rage sukari a cikin bidiyon a cikin wannan labarin.

Sharuɗɗan da yanayin ajiya

Gliformin magani ne.

Dole ne a adana shi a cikin busassun wuri, wanda ba zai yiwu ba zuwa shigarwar hasken rana, a zazzabi har zuwa 25 ºС. Tare da ingantaccen ajiya, rayuwar shiryayyen allunan 500 MG shine shekaru 3, allunan 850 MG da 1 gram - 2 years.

An sami kuskure a cikin rubutun? Zaɓi shi kuma latsa Ctrl + Shigar.