Siofor: contraindications da sakamako masu illa

Magungunan da aka ba da shawarar don magance ciwon sukari suna kuma shahara a cikin waɗanda ke son asarar nauyi: Siofor sananne ne musamman a cikin wannan rukuni - umarnin don amfani da asarar nauyi ba ya ƙunshi amfani da shi, amma har ma likitocin lokaci-lokaci suna ba da irin wannan shawarar. Shin wannan ƙwayar magunguna da kwayar cutar ta analogues na shafar adon mai da yadda za a zaɓi madaidaicin kashi, wanda ba zai cutar da jikin ba?

Allunan

Daga cikin magungunan da aka gabatar da su ta hanyar warkewa mutane na fama da ciwon sukari na 2, wanda aka tsara sosai shine Siofor. Ana amfani dashi duka don maganin cutar da ta kasance, da kuma prophylaxis, tunda yana canza matsayin juriya ga insulin, babban dalilin yawan sukari kuma, mahimmanci, wuce kima. Wannan gaskiyar ta zama babban dalilin da yasa likita zai iya ba da shawarar Siofor don asarar nauyi ga mai haƙuri. Ana samuwa a cikin nau'ikan Allunan tare da ɗaukar hankali daban-daban na abu mai aiki.

Ari, amfani da wannan magani yana shafar:

• tsarin zuciya
• alamomin triglycerides,
• cholesterol.

Magungunan Siofor don asarar nauyi yana ɗaukar "kari" da yawa masu mahimmanci, ba a kirga ikon sarrafa sukari na jini ba:

• Rage cin abinci, wanda ke taimakawa ci gaba da rage cin abinci ko kuma sauƙaƙewar abincin.
• Bayyanar da kwayoyin hormones (mata suna da wahalar rasa nauyi saboda matsalolin tsarin endocrine).

Siofor - abun da ke ciki

Don fahimtar cikakkiyar ƙimar wannan ƙwayar dangane da asarar nauyi, nazarin umarnin ya kamata ya fara da jerin abubuwan da ke tattare da shi. Abun da Siofor ya ƙunsa ya haɗa da kayan haɗin metformin - wannan wakilin ɓangaren biguanide ne, wanda ke da tasirin gaske a jiki. I.e. yin amfani da wannan abu yana taimakawa rage matakan sukari, kuma muhimmiyar amfani da metformin shine rashin fashewa da kodan. Rashin halayen wannan siofor ba su da yawa, kuma daga cikin "kari" daga amfani da shi, an nuna raguwa a cikin TSH.

Baya ga metformin, Siofor ya ƙunshi abubuwa masu taimako (gami da abubuwan fashewar):

• maganin
• povidone
• magnesium stearate,
• macrogol
• titanium dioxide.

Siofor - umarnin don amfani

Shin kunyi tunani game da asarar nauyi ta hanyar raguwa a yawan canji a cikin insulin, ko kuna nufin hana ciwon sukari, kuna buƙatar gano wanda aka ba da shawarar yin amfani da Siofor, yadda za a yi da kuma yadda za a zabi sashi. Umarni na hukuma na Siofor ya bayyana cewa kawai mellitus na ciwon sukari (nau'in II) ana iya ɗauka shine kawai alama don amfani, yayin da waɗannan allunan ana ɗaukarsu "makoma ta ƙarshe", ana amfani dasu ne kawai idan babu sakamako daga abincin da aka tsara kuma ayyukan ayyukan jiki don asarar nauyi.

Siofor 500 don asarar nauyi

Minimumarancin adadin metformin wanda zai yiwu ga Siofor (gwargwadon tsarin magunguna na Rashanci) shine 500 MG. An yarda da amfani da irin wannan kwamfutar hannu ko da a cikin yara, kuma mutanen da ke yin la'akari da zaɓin rasa nauyi tare da Siofor, yana da kyau a yi wannan zaɓi. A cikin masu ciwon sukari, likitoci suna ba da shawarar 2 don amfani da miyagun ƙwayoyi:

• kamar yadda maganin tauhidi - 500 a sau 2 a rana,
• haɗe tare da insulin (idan dogaro) - haɓaka daga 500 MG zuwa 2000 MG kowace rana, i.e. daga liyafar 1 zuwa 4.

Idan muna magana kan yadda za a ɗauka Siofor 500 don asarar nauyi, to yana da kyau a zauna a kan zaɓi na monotherapy da umarnin hukuma ya gabatar: sha 1 kwamfutar hannu na Siofor 500 Allunan na wata daya. kowace rana. Yi wannan tare da abinci ko bayan shan shi, saboda yin amfani da metformin an cika shi da haushi. Minimumarancin magani na Siofor akan aiwatar da nauyin nauyi yana shafar hankali, amma mummunan halayen da ake samu dashi ba kasala bane. Tare da haƙuri mai kyau, koyarwar ta ba da damar ƙara yawan zuwa allunan 2 na Siofor.

Siofor 850

Wannan zabin sashi, bisa ga umarnin hukuma, abu ne mafi kyau ga masu ciwon sukari, amma a cikin mutum mai lafiya ana iya ganin shi "mai nauyi", don haka ya kamata ya fara da rabin kwamfutar hannu. Ana amfani da Siofor 850 don asarar nauyi sau da yawa fiye da Siofor 500, amma shawarwarin gaba ɗaya da tanadi na umarnin daga masana'anta sune iri ɗaya:

• Matsakaicin adadin yau da kullun na 3,000 MG na metformin, har ma don asarar nauyi mai sauri, an haramta shi wucewa.
• Aikin rasa nauyi akan wannan magani shine wata daya ko kasa.
• Bayan makonni 2, zaku iya fara shan maganin a cikin sashi mai girma - Allunan 2 na 850 MG kowace rana.

Siofor 1000

Versionaƙƙarfan ƙarfi na wannan maganin maganin cututtukan da kamfanonin magunguna ke bayarwa shine Siofor 1000. Likitocin sunyi la'akari da amfani da miyagun ƙwayoyi a cikin wannan sutura don asarar nauyi mara hankali, tunda wannan riga mai tasiri ne akan jikin. Kodan na iya wahala sosai sosai, tunda metformin bashi da cikakken lafiya, kuma tasirin matakan glucose a bayyane yake. Kafin ka tsara yadda ake ɗaukar Siofor 1000 don asarar nauyi, ƙaddamar da gwajin sukari, saboda sashi, bisa ga umarnin, aka zaɓi bisa ga shi.

Bayan 'yan wuraren aikace-aikace na wannan magani:

• Sigar farko don asarar nauyi shine kwamfutar hannu 1/4. A cikin 'yan kwanaki za ku iya ɗaukar rabin kwayoyin, kuma a ƙarshen ƙarshen mako, idan babu sakamako mara kyau, sai na sumbace ku.
• Yana da kyau a cire carbohydrates mai sauƙi daga abincin don tsawon wannan maganin. yana toshe asirinsu. Daga sake dubawa zaku iya ganin cewa amfani da wannan kwaya da kukis ko Sweets suna haifar da mummunan tashin hankali.

Siofor yayin daukar ciki

Iyaye mata masu gwaji suna rasa nauyi akan wannan magani mara amfani. Likitocin Rasha gaba daya sun haramta Siofor a lokacin daukar ciki, suna bayyana matsayinsu ta hanyar cewa yawan karatu kan lafiyar yara da aka haifa ga matan da suka yi amfani da shan wannan magani bai isa don m amincewa da "don" ko "akasin". Idan akwai shakku game da amincin miyagun ƙwayoyi, mahaifiyar mai tsammani ta fi dacewa ta tabbata kuma ta bar kwayar kwalliya, saboda akwai hanyoyi da yawa na rasa nauyi (mai laushi) na tsawon lokacin jiran jaririn.

Siofor - analogues

Likitoci sun kira magunguna 2 kawai don maye gurbinsu sosai a cikin maganin cututtukan sukari da haɓaka sukari bisa ga sakin layi na kayan aiki da kuma janar na koyarwa:

Kowane analog na Siofor da aka ƙayyade daidai yake da wannan maganin a babban bangaren. Ana iya samun su koda guda sashi ɗaya - daga 500 zuwa 1000 MG, don haka ƙa'idar amfani ba ta canzawa, koyarwar tana maimaita kusan harafin a cikin wasiƙar umarnin zuwa Siofor. Bambanci kawai shine abun da ke ciki da gaskiyar cewa likitoci suna ba da shawara ga Glucofage ya sha kafin abinci, kuma ba bayan. Game da yadda ake ɗaukar Metformin don asarar nauyi, a nan duk abu ɗaya yake da umarnin umarnin miyagun ƙwayoyi Glyukofazh.

Siofor - contraindications da sakamako masu illa

Amincin wannan magani yana da kusanci - koda daga sake dubawa zaku iya ganin jikin yana iya amsawa sosai ga metformin a cikin kwanakin farko na gudanarwa. Menene illolin sakamako na Siofor? Mafi yawa ana amai da gudawa, i.e. narkewa na narkewa, amma ana iya samun asarar sani, kuma a lokuta masu yawan haɗuwa da yawa - rashin lafiya. Idan yayin nauyi asara tare da wannan magani ba ku ɗauki carbohydrates mai sauƙi daga abincinku ba, zasu haifar da gag reflex.

Bayan 'yan kogo daga umarnin hukuma:

• Lokacin shan wannan magani, abincin yau da kullun ya kamata "yayi" fiye da adadin kuzari 1000.
• Dogaro masu yawa na jiki, musamman ma abubuwan sararin samaniya, an haramta.
• An haramta shan giya da kwayoyi waɗanda ke ɗauke da aidin.

Contraindications zuwa wannan magani, likitoci suna kiran nau'in ciwon sukari na guda ɗaya (ana iya amfani dashi ta musamman ta hanyar takardar sayan magani, a cikin tandem tare da insulin), cutar koda mai raɗaɗi, cutar hanta. Oncology shima dalili ne na hana asarar nauyi tare da Siofor. Dangane da umarnin hukuma, bai kamata ku sha wannan magani ba yayin cututtukan cututtuka da kuma cikin maganin dogaro. Haɗuwa da kwayoyi masu ɗauke da ethanol abu ne mai kyau a hana.

Bidiyo: Ciwon sukari da Slimming Siofor

Inna, ɗan shekara 29 ban ga babban bambanci tsakanin Siafor1000 da Siafor500 ba, na sha biyun. Kowane kwamfutar hannu 1, karatun yana makonni biyu. Kodayake sashi na ƙasa bai yi kyau ba, kodayake sashi yana da yawa, akwai sakamako guda ɗaya kawai - mummunan horo na tilasta! Lokacin da kake ƙoƙarin cin kukis, amai yana farawa, saboda maganin yana toshe abubuwan carbohydrates. Ya shafi mutanena haka kuma dai na yi zunubi a jikina.

Galina, 36 years old Siafor500 - 24/7 maye gurbin abinci mai gina jiki! Zai fi kyau ƙoƙarin cin wani abu ban da kayan lambu / 'ya'yan itatuwa (Hakan ma yana tsallake tafarnuwa, amma saboda wasu dalilai ba tare da madara ba), duk "sakamakon" sakamako nan da nan ya buɗe - ciki ya fashe, tashin zuciya yana faruwa, jin zafi a ciki. A cikin mako irin wannan "Kasadar", Na rasa al'ada ta rasa nauyi da abinci da hana nauyi asara, kuma na rasa kilo 4 a kowane wata.

Olga, ɗan shekara 23 ban sha wahala daga ciwon sukari ba, Na faɗi a Siofor ba da gangan ba, na sayi (mai kyau, mai arha), ya sha wata ɗaya. Ban lura da wani ƙarin sakamako akan asarar nauyi ba, kuma na danganta ɓace 2.5 kilogiram ga abinci mai narkewa, wanda umarnin likita ya buƙace shi. Amma jerin abubuwanda zasu iya haifarda sakamako masu yawa, harma baza'a iya hada bitamin tare da magani ba.

Rita, ɗan shekara 30 na ga Siofor850 na daidai makonni 3, na cinye shawarar shawarar abokina wanda ya yi rashin nauyi tare da shi. Hanyoyin ciki sun fara yin fushi, duk da cewa an ɗauki kwayar bayan an ci abincin dare. Na koyi cewa yana da kyau a sha kwatancen bayan auna matakin sukari, kuma kar a kwashe shi da makanta daga umarnin. Na wuce gwajin, na fara shan rabin kwamfutar hannu - ya ci gaba sosai.

Formaddamar da tsari da abun da ke ciki

Ana samar da miyagun ƙwayoyi a cikin nau'i mai kwakwalwa

• Siofor 1000: kusa, a gefe guda tare da ɗaukar hoto mai siffar “snap-tab”, a ɗayan haɗarin, fararen fata (inji (15 inji mai kwakwalwa. A cikin tafin fuska, a cikin kwalin kwali na 2, 4 ko 8 bugun kansa)),
• Siofor 850: madaidaiciya, tare da daraja mai kyau-biyu, fararen fata (guda 15 kowane daya a cikin alkuki, a cikin kwali na kunshin 2, 4 ko 8 bugun kansa),
• Siofor 500: biconvex, zagaye, fararen fata (guda 10 kowannensu a cikin alkuki, a cikin kwalin kwali na 3, 6 da 12 blisters).

Abun ciki 1 kwamfutar hannu:

• Abunda yake aiki: metformin hydrochloride - 1000, 850 ko 500 MG,
• Componentsarin abubuwan da aka haɗa: magnesium stearate, povidone, hypromellose, harsashi: titanium dioxide (E171), macrogol 6000, hypromellose.

Alamu don amfani

An ba da shawarar yin amfani da miyagun ƙwayoyi don amfani da su a cikin lura da nau'in mellitus na II na ciwon sukari, musamman a cikin marasa lafiya masu kiba a cikin rashin tasirin ayyukan motsa jiki da abubuwan abinci na warkewa.

Ana iya amfani da Siofor azaman magani na monotherapy ko a hade tare da sauran wakilai na maganin hypoglycemic na baki da insulin.

Sashi da gudanarwa

Ana shan Siofor a baki yayin cin abinci ko kuma bayan cin abinci.

Dokar da za a iya amfani da ita da kuma tsawon lokacin shan magani ana kaddara ta ne ga likitocin da ke halartar juna daban-daban, tare da yin la’akari da tattarawar glucose a cikin jini.

A lokacin monotherapy, an wajabta wa 500 MG 1-2 sau a rana a farkon hanya (1 kwamfutar hannu 1 500 mg ko 1 /₂ Allunan 1000 mg) ko 1 lokaci a rana don 850 MG na miyagun ƙwayoyi. Kwana 10-15 bayan farawar magani, ana samun karuwar hankali a cikin kashi na Siofor a kowace rana har zuwa allunan 3-4 na 500 MG, allunan 2-3 na 850 MG ko allunan 2 na 1000 MG.

Matsakaicin adadin yau da kullun na iya zama ba fiye da 3000 MG (allunan 3 na 1000 mg ko allunan 6 na 500 MG) sun kasu kashi uku. Lokacin da aka tsara allurai na 2000-3000 MG a rana, zaku iya maye gurbin allunan 2 na 500 na MG a kwamfutar hannu guda 1 a cikin 1000 mg.

Idan mai haƙuri ya canza zuwa metformin tare da jiyya tare da wani wakilin antidiabetic, na ƙarshen an soke kuma an dauki Siofor a cikin allurai da aka bada shawarar a sama.

Don haɓaka sarrafa glycemic, ana iya tsara maganin a hade tare da sinulin. A wannan yanayin, kashi na farko ga manya shine 500m wanda aka sha sau 1-2 a rana, ko kuma 850 MG sau ɗaya a rana. A hankali (idan ya cancanta) ana karuwa da kashi kowane mako zuwa Allunan Allunan na 3-4 na 500, allunan 2 na 1000 mg ko Allunan 2-3 na 800 MG.

Matsakaicin insulin an ƙaddara shi gwargwadon matakin glucose a cikin jini. Matsakaicin adadin metformin shine 3000 MG kowace rana, an kasu kashi uku.

A cikin tsofaffi marasa lafiya, lokacin da aka saita kashi na Siofor, ana yin la’akari da abin da ke cikin creatinine a cikin plasma (saboda yuwuwar aikin keɓaɓɓen aiki).

A lokacin aikin jiyya, wajibi ne don kimanta aikin koda.

Yara 10-18 na shekara lokacin shan monotherapy ko a hade tare da insulin a farkon hanya ana ba da shawarar shan 500 ko 850 MG sau ɗaya a rana, bayan kwanaki 10-15 ana samun karuwar hankali a kashi. Matsakaicin adadin kowace rana ga yara shine 2000 MG, ya kasu kashi 2-3.

Side effects

• Harkokin hanta da kuma biliary fili: lokuta guda ɗaya - hepatitis ko sakewa mai karuwa a cikin ayyukan hepatic transaminases (ɓacewa bayan cire magunguna),
• Tsarin mara lafiyar: sau da yawa - ɗanɗanar damuwa,
• Allergic halayen: da wuya wuya - halayen fata (urticaria, itching, hyperemia),
• Tsarin narkewa: amai, ɗanɗano na ƙarfe a cikin bakin, tashin zuciya, zawo, rashin ci, damuwar ciki (waɗannan tasirin yakan haifar da farawa a farkon hanya kuma yawanci yakan tafi da kansu, don hana su, ya kamata a ƙara yawan adadin yau da kullum a hankali kuma a raba su 2-3 liyafar)
• Metabolism: mai wuya - lactic acidosis (ana buƙatar karɓar magani), tare da yin amfani da dogon lokaci - rage yawan bitamin B₁₂ kuma raguwa a cikin matakinsa a cikin jini na jini (yana da mahimmanci a la'akari da marasa lafiya tare da cutar megaloblastic).

Lokacin amfani da miyagun ƙwayoyi a allurai har zuwa 85 g, ba a lura da ci gaban hypoglycemia ba.

Idan akwai wani babban abin maye, zazzabin lactic acidosis na iya faruwa, wanda ke bayyane ta waɗannan alamomin kamar haka: amai, raɗaɗin ciki, zawo, tashin zuciya, amai, raunin hanji, rauni mai ƙarfi, sassauya bradyarrhythmia, raguwar hauhawar jini, hauhawar jini, rikicewa da asarar hankali, raɗaɗin tsoka.

A wannan yanayin, ana buƙatar karɓar magani na gaggawa da kuma asibiti na gaggawa. Hanyoyi mafi inganci don cire Siofor daga jiki sun haɗa da maganin hemodialysis.

Umarni na musamman

Maganin Metformin ba a matsayin musanya ga motsa jiki da abinci na yau da kullun ba, waɗannan magungunan marasa magani suna buƙatar haɗe tare da Siofor kamar yadda likitanka ya umarta. Dukkanin marasa lafiya yakamata su bi abincin da ke tattare da yawan carbohydrates a cikin kullun, kuma daidaikun mutane masu kiba su bi tsarin rage kalori.

Haɗin metformin zai iya haifar da tarin lactic acid a cikin jini, wanda hakan yana ba da gudummawa ga ci gaban irin wannan yanayin mai haɗari sosai kuma mai haɗari kamar lactic acidosis. Ci gabansa a cikin marasa lafiya da ciwon sukari mellitus an lura da gaske a gaban mai girma na koda gazawar. Yin rigakafin wannan rikitarwa ya ƙunshi gano duk dalilai masu haɗari, waɗanda suka haɗa da: yawan shan giya, tsawan azumi, bugun kirji, gazawar hanta, ƙwayar ketosis da duk wani yanayin da ke hade da hypoxia.

Kafin farkon farawar, da kuma a kai a kai a lokacin gudanar da aikin, yakamata a tantance yawan plasma na creatinine.

Ana buƙatar sa ido na musamman lokacin da akwai barazanar aikin naƙasa mai rauni (alal misali, a farkon fara amfani da maganin diuretics, magungunan antihypertensive, magungunan anti-inflammatory marasa steroidal).

Lokacin da ake rubuta gwajin X-ray, tare da gudanarwa na ciki na iodine wanda ke da bambanci na matsakaici, sa'o'i 48 kafin da bayan aikin, Siofor ya kamata a maye gurbin Siofor na ɗan lokaci tare da wani wakili na hypoglycemic. Komawa da metformin yana halatta ne kawai idan ma'anar maida hankali a cikin al'ada abu ne na al'ada.

Hakanan ana buƙatar soke ƙwayar miyagun ƙwayoyi awanni 48 kafin aikin tiyata da aka shirya a ƙarƙashin maganin sa barci na gaba ɗaya, tare da maganin kashin baya ko na epidural. An ba da izinin ci gaba da ɗaukar cutar ba a cikin sa'o'i 48 ba bayan tiyata (ko tare da sake dawo da abinci na baka).

A cikin yara da matasa 10-18 years old, da ganewar asali na type II ciwon sukari mellitus ya kamata a tabbatar kafin shan miyagun ƙwayoyi. Yaran da ke shan metformin, musamman waɗanda shekarun shekaru 10-12 (lokacin zaɓar) sun buƙaci saka idanu na musamman game da haɓaka da abubuwan ci gaba.

Monotherapy tare da miyagun ƙwayoyi ba ya haifar da hypoglycemia, duk da haka, an ba da shawara sosai yayin shiga cikin ayyukan da ke buƙatar halayen hanzari da haɓaka mai da hankali (gami da tuki motocin) lokacin yin aikin haɗin gwiwa tare da abubuwan da aka samo asali na sulfonylurea ko insulin saboda yiwuwar barazanar wannan yanayin ilimin.

Hulɗa da ƙwayoyi

Yayin jiyya tare da Siofor, ba a ba da shawarar shan abin sha ko shirye-shiryen da ke kunshe da ethanol ba, saboda haɓakar haɗarin lactic acidosis (musamman a kan yanayin rashin abinci, abinci, ko gazawar hanta).

Haɗuwa da metformin tare da wasu magunguna waɗanda ke buƙatar kulawa ta musamman saboda yiwuwar halayen hulɗa:

• Cimetidine - kawar da metformin yana raguwa, haɗarin lactic acidosis yana da ƙaruwa,
• Magungunan cationic (quinidine, procainamide, morphine, amiloride, vancomycin triamteren, ranitidine) sun ɓoye a cikin tubules - matsakaicin ƙwayar plasma na metformin yana ƙaruwa,
• Danazole - haɓakar tasirin sakamako mai yuwuwu ne (ana iya buƙatar sauya sirin na Siofor),
• Nifedipine - matsakaicin maida hankali da kuma daukar nauyin metformin a cikin plasma yana ƙaruwa, lokacin aikinsa yana tsawaita,
• Abubuwan da aka samo na phenothiazine, epinephrine, hormones thyroid, glucagon, acid nicotinic, maganin hana haihuwa - yana kara maida hankali na glucose a cikin jini,
• Angiotensin-mai canza enzyme (ACE) inhibitors da sauran magungunan antihypertensive - mai yiwuwa rage girman glucose na jini,
• Abubuwan da suka samo asali na sulfonylureas, acarbose, salicylates, insulin - ana inganta tasirin hypoglycemic,
• Diuretics, beta-adrenergic agonists, glucocorticoids (don amfani da tsari da Topical) - matakan glucose na jini yana ƙaruwa,
• Kai tsaye anticoagulants - sakamakonsu ya raunana,
• Furosemide - maida hankali da rabin rayuwa an rage su.

Propertiesungiyoyin magunguna na Siofor

Metformin shine biguanide wanda ke da tasirin hypoglycemic, yana samar da raguwa a cikin yawan abubuwan kwalliya na basal da postprandial a cikin jini. Metformin baya motsa insulin insulin kuma sabili da haka baya haifar da ƙwanƙwasa jini. Sakamakon rage yawan sukari na metformin mai yiwuwa ne saboda irin waɗannan hanyoyin: raguwar samarwa da glucose a cikin hanta sakamakon hana gluconeogenesis da glycogenolysis, haɓaka ƙwarewar ƙwayar tsoka zuwa insulin, wanda ke inganta haɓakar glucose a kan mamayewa da kuma yin amfani da shi, da rage raguwar glucose a cikin hanta. Metformin, yana aiki akan glycogen synthetase, yana ƙarfafa aikin haɗin glycogen, yana haɓaka ƙarfin sufuri don glucose na dukkanin sunadaran jigilar ƙwayar membrane da aka sani a baya (GLUT). A cikin mutane, metformin yana da tasiri mai kyau a cikin mai mai, ba tare da la’akari da tasirin sa ga glucose na jini ba, kuma yana rage matakin cholesterol, LDL cholesterol, da plasma TG. Rage abubuwan TG a cikin serum, shi ma yana da tasirin antithrombotic.
Bayan gudanarwa na maganin metformin, mafi girman aikinsa a cikin jini yana isa bayan awa 2.5, cikakken bioavailability shine kashi 50-60%.
Lokacin ɗauka ta baka, ɗaukar metformin bai cika ba kuma yana da halin jikewa, an yi imani cewa metformin yana da magunguna marasa kan gado. Lokacin amfani da miyagun ƙwayoyi a cikin adadin da aka saba kuma a lokaci na yau da kullun, daidaituwa game da maida hankali a cikin jini na jini bayan sa'o'i 24 da 48. Za'a iya yin watsi da haɗin lafiyar protein na jini. Metformin yana shiga cikin sel jini. Matsakaicin maida hankali a cikin jini gaba daya yana ƙasa da na jini, kuma an kafa shi kusan lokaci guda. An cire Metformin wanda baya canzawa a cikin fitsari. A cikin mutane, ba a yanke shawarar kayayyakin lalata ba. Enaladdamar da azabtarwa na metformin 400 ml / min, wanda ke nuna narkar da metformin saboda karɓar ɗaukar ciki da ƙonewar tubular. Tare da kashi na baka, cire rabin rayuwa shine awoyi 6.5. Idan aikin dan adam ya karu, toshewar koda yana raguwa gwargwadon karɓar ƙirar creatinine, hakan zai kara kawar da rabin rayuwa kuma yana ƙaruwa da haɗuwa da metformin a cikin jini na jini.

Amfani da maganin Siofor

Sanya a cikin kashi na farko na 500 MG / rana, sannu a hankali yana ƙaruwa har sai an sami kashi na warkewa. Bayan kwanaki 10-15, ya zama dole don gyara kashi bisa ga alamu na matakan glucose na jini. Increasearawar hankali a cikin ƙwayar cuta yana da tasirin gaske akan ji na ƙwarai zuwa shirye-shiryen narkewar hanji. Matsakaicin adadin yau da kullun ga manya shine 0.5-3 g na metformin hydrochloride, wanda yayi daidai da allunan 1-6 na Siofor 500 ko 3 g zuwa 3 Allunan na Siofor 1000. Don cimma ingantaccen gyaran matakan glucose na jini, ana iya haɗuwa da metformin tare da insulin. A lokaci guda, ana wajabta Siofor a cikin kashi na yau da kullun (500-850 mg sau 2-3 a rana), yayin da kashi na insulin ya dogara da karatun matakan glucose na jini. Allunan ana ɗaukar su tare da abinci, suna shan ruwa mai yawa.

Contraindications don amfani da miyagun ƙwayoyi Siofor

Hypersensitivity zuwa metformin ko wasu abubuwan maganin, ƙwayar cuta ta metabolism (yanayin hypoxic na asalin asali, ciwon sukari ketoacidosis, ciwon sukari da coma), gazawar renal ko rashin aiki na renal (misali, serin creatinine 135 μmol / L a cikin maza da 110 μmol / L - cikin mata), matsanancin yanayi wanda ke haifar da lalacewar aikin haɓaka (misali, zazzabin cizon sauro, kamuwa da cuta mai ƙarfi, girgizawa), gudanarwar ƙwayar cutar kwatankwacin jami'ai masu ɗauke da sinadarin iodine, matsanancin cuta da cututtukan fata hypoxia (alal misali, mummunan lalacewar tsarin na zuciya, bugun zuciya ko gazawar numfasawa, matsanancin myocardial infarction, gigicewa), gazawar hanta, yanayin catabolic (alal misali, idan akwai hanyoyin ciwace-ciwace), matsanancin giya mai maye da rashin shan giya, yayin daukar ciki da lactation.

Sakamakon sakamako na miyagun ƙwayoyi Siofor

Daga narkewa
Mafi yawan lokuta (10%) akwai korafi na tashin zuciya, amai, zawo, ciwon ciki da kuma rashin ci. Suna bayyana sau da yawa a farkon hanya kuma a mafi yawan lokuta suna wucewa da sauri. Sau da yawa (1-10%) dandano mai ƙarfe yana bayyana a bakin.
Fatar fata
Da wuya (≤0.01%) a cikin marasa lafiya tare da rashin damuwa, erythema mai sauƙi ya bayyana.
Daga gefen metabolism
Da wuya (≤0.01%), an rage raguwa a cikin ƙwayar bitamin B12, kuma tare da tsawan magani, raguwa a cikin taro a cikin jini. A zahiri, wannan lura ba mai dacewa bane.
Lactic acidosis
Da wuya sosai (lokuta 0.03 a cikin marasa lafiya 1000 a kowace shekara), akasari tare da yawan abin sama da ya kamata, da kuma shan giya.

Abun hulɗa na miyagun ƙwayoyi Siofor

Haɗuwa da ke buƙatar kulawa ta musamman
Yin amfani da lokaci ɗaya na sauran wakilai na hypoglycemic da insulin, NSAIDs, MAO inhibitors, oxygentetracycline, ACE inhibitors, fibrates, cyclophosphamide yana haifar da tasirin hypoglycemic na Siofor. Cimetidine yana rage jinkirin kawar da metformin kuma yana ƙara haɗarin lactic acidosis.
Rage tasirin hypoglycemic na Siofor corticosteroids, magungunan estrogen-progestogen, haɗin gwiwa, shirye-shiryen hodar iblis, glucagon, phenothiazines da thiazide diuretics, abubuwan asali na nicotinic acid. Sabili da haka, ƙarin saka idanu akan matakan glucose na jini a cikin marasa lafiya da ke karɓar waɗannan magunguna wajibi ne, musamman a farkon jiyya. Idan ya cancanta, ana aiwatar da gyaran fuska na maganin antidiabetic duka a lokacin wannan magani da kuma bayan an daina shi. Amfani akai-akai na huar gum ko colestyramine yana lalata shaye-shayen kuma yana rage tasirin sa.
Ba da shawarar haɗuwa ba
Yin amfani da barasa a lokaci guda na iya inganta tasirin maganin ƙwaƙwalwar ƙwayoyi kuma yana haifar da ci gaba da lactic acidosis, musamman tare da yunƙurin abinci, rashin abinci mai gina jiki ko tare da lalacewar hanta.

Doaukar cutar Siofor, alamu da magani

A kashi na 85 g na metformin, hypoglycemia bai inganta ba, koda kuwa lactic acidosis ya haɓaka a ƙarƙashin yanayin guda. Tare da babban yawan abin sama da ya kamata da kuma kasancewar abubuwanda ke haifar da haɗari, lactic acidosis na iya haɓaka. Wannan lamari ne na gaggawa wanda magani na ciki ya zama dole. Hanya mafi inganci don kawar da lactate da metformin shine hemodialysis.

Makoma Siofora

Mutane da yawa suna kuskuren fahimtar Siofor 850 a matsayin wata hanya, babban dalilin shi shine asarar nauyi.

Babban manufar wannan magani shine rage yawan sukarin jini a cikin mutanen da ke fama da ciwon sukari. Kiba a cikin waɗannan halayen ya zama ruwan dare gama gari, ana alakanta shi da yawan haɗuwa da glucose a cikin jini da kuma saurin raguwar matakan metabolism.

Magungunan sun ƙunshi metformin, wanda ke rage sukari jini da rushe ragowar cholesterol. Saboda haka, masu ciwon sukari na iya rasa nauyi. Mutane masu lafiya a wasu yanayi ma suna amfani da wannan magani.

Nazarin game da Siofor na mutanen da ke da ƙoshin lafiya waɗanda ke son rasa nauyi galibi ba su da kyau, saboda ba tare da yin magana da likita ba kuma bin umarnin, asarar nauyi ba ta faruwa, kuma sakamakon illa yana faruwa.

Idan mutum ba shi da babban matakin glucose a cikin jini, to raguwa mai kaifi a ciki na iya zama cutarwa, har zuwa rikicewar endocrine da bayyanar coma mai narkewa, lokacin da sukari ya sauka zuwa ƙima mai ƙima.

Magungunan Siofor yana da alamun analogues kamar haka:

• Glycon.
• Bagomet.
• Glucophage.
• Gliformin.
• Vero-Metformin.
• Glycomet 500.
• Dianormet.
• Langerine.
• Methadiene.
• Glyminfor.
• Metfogamma 1000.
• Dormin
• Metospanin.
• Metformin.
• Metfogamma.
• Metfogamma 500.
• NovoFormin.
• Metformin-BMS.
• Siofor 500.
• Metformin Richter.
• Sofamet.
• Tsarin tsari.

Tsarin magunguna da abun da ke ciki na maganin

An kirkiro maganin Siofor don rage sukarin jini a cikin mutanen da ke da tabbacin nau'in ciwon sukari na 2. Irin waɗannan marasa lafiya suna da kiba sosai.

A cikin umarnin ga kayan aiki babu bayanai game da yiwuwar amfani da shi ta hanyar lafiyar mutane don asarar nauyi. Lokacin da metformin ya shiga jikin mai ciwon sukari, yana shafar ƙwayoyin tsoka don haɓaka ikon su don ɗaukar glucose mai yawa daga jini.

Wannan tasirin yana aiki ne kawai ga jikin mutanen da ke fama da ciwon sukari na 2. Ga wadanda basu da irin wannan cuta, amfani da irin wadannan magunguna ya zama mara amfani. Wannan ya shafi magungunan Siofor.

Tsarin dijital, wanda yake wajibi ne bayan sunan haruffan samfurin, shine ƙayyadadden sashi. A halin yanzu, ana sayar da maganin Siofor a sigogi:

Hanyar aikin

Magungunan yana rage darajar asali na sukari a cikin jini, da kuma alamta bayan cin abinci. Metformin baya tilasta wa ƙwayoyin beta na pancreatic su samar da insulin da yawa, wanda ke nufin cewa hypoglycemia ba zai bayyana ba.

Hanyar rage adadin sukari lokacin amfani da Siofor shine haɓaka iyawar sel don ɗaukar sukari daga jini. Bugu da ƙari, ƙwayar insulin na sel membranes yana ƙaruwa.

Siofor yana rage yawan shan carbohydrates daga abinci a cikin hanji da ciki. Hakanan yana haɓaka hada hada-hada da kitse acid wanda aka inganta kuma yana inganta anaerobic glycolysis. Siofor a cikin ciwon sukari yana rage yunwa, wanda shima yana taimakawa rage nauyi. A cikin mutanen da basu da ciwon sukari, waɗannan kwayoyin basu rage yawan haɗuwar glucose ba. Ba a gano ayyukan siofor a wannan yanayin ba.

Masu ciwon sukari waɗanda ke ɗaukar Siofor kuma suna bin wani abinci na musamman wani lokaci sukan rasa nauyi. Wannan hujja ta tabbatar da labarin karya cewa metformin wata hanya ce ta rasa nauyi.

Idan da gaske magungunan sunada nauyi sosai, za'a wajabta shi ga duk masu ciwon sukari.

Abin baƙin ciki, mutanen da ke fama da ciwon sukari waɗanda ke amfani da Siofor na dogon lokaci daga 500 zuwa 850 MG sau da yawa a rana da wuya a lura da asarar nauyi mai yawa.

Umarnin don amfani da miyagun ƙwayoyi

An ba da umarnin sashi na miyagun ƙwayoyi ta musamman daga likitan halartar. A matsayinka na mai mulkin, amfani da miyagun ƙwayoyi yana farawa da mafi ƙarancin 500 MG.

An tsara Siofor a cikin farkon farawa na 500 MG / rana, a kan lokaci, adadin yana ƙaruwa har sai an kai matsayin da ake so. Bayan kwanaki 10 - 15, ya kamata a daidaita sashi ta amfani da alamar nuna sukari na jini. Graduarawar da ya yi yawa a hankali yana shafar hankalin mai ƙwaƙwalwa zuwa shirye-shiryen narkewar abinci.

Matsakaicin adadin 0.5-3 g na metformin hydrochloride an yarda da kowace rana, wannan ya dace da Allunan 1-2 na Siofor 500 ko 3 g zuwa 3 Allunan na Siofor 1000. Ana iya amfani da wannan kashi sau uku a rana, amma, a mafi yawan lokuta, don maganin ciwon sukari ya isa sau 100 sau biyu a rana.

Don cimma ingantacciyar gyaran sukari na jini, ana haɗuwa da metformin tare da insulin.

Na farko, ana tsara Siofor a 500 - 850 MG sau da yawa a rana, yayin da adadin insulin ya dogara da matakin sukari a cikin jini. Ya kamata a sha miyagun ƙwayoyi tare da abinci, ba tare da taunawa ba, sha shi da isasshen adadin ruwa.

Sau da yawa ana amfani da sashi na 500 MG idan akwai ciwon suga ko kuma mutum yana jin nauyi. Idan mai ciwon sukari bashi da tasirin sakamako bayan sati daya na amfani, to yawan maganin yana ƙaruwa, alal misali, ana amfani da Siofor 850 ko kuma an ƙara wani kwamfutar Siofor 500 sa'o'i 12 bayan na farko. Kowace mako, ana ƙara 500 MG na metformin a hankali, amma yana da mahimmanci a kula da kasancewar ko rashin sakamako masu illa.

Idan adadin magungunan Siofor ya ƙaru, to akwai lahanin sakamako masu illa. Sannan kuna buƙatar rage sashi zuwa adadin da ya gabata. A tsawon lokaci, yakamata a sake gwada ƙara yawan ƙwayar zuwa mafi inganci.

Idan maganin da aka tsara na maganin shine 500 MG, ya bugu sau 1 da yamma, don haka rage haɗarin sakamako masu illa. Idan sashi shine 1000 MG kowace rana, to kashi ya kasu kashi dayawa.

Yana da mahimmanci yayin magani tare da kwayoyi na wannan aji don yin gwaje-gwaje koyaushe waɗanda ke nuna aikin hanta da kodan. Musamman ma, ya kamata a aiwatar da masu zuwa:

1. janar gwajin jini
2. gwajin jini na biochemical (enzymes hanta, creatinine).

Jerin maganin hana daukar ciki

Siofor 850 magani ne mai ƙarfin gaske wanda ba a bada shawara don amfani ba tare da tuntuɓar likita ba.

Idan an yanke shawara don ɗaukar Siofor, to, contraindications kamar haka:

• babban abin lura ga abubuwan da aka samar da kayan,
• rikicewar endocrine,
• gazawar numfashi
• nau'in ciwon sukari guda 1
• hanta da koda,
• mummunan raunin da ya faru
• infandirewa mai wucewa cikin mataki na wuce gona da iri,
• mummunan cututtuka
• kwanan nan ayyukan
• ciwan ciki
• na kullum,
• ciki
• karancin abincin kalori
• shekarun yara
• nono.

Likitoci suna ba da magani a cikin matsanancin yanayi. Ya kamata a dauki Siofor 850 da taka tsantsan:

1. mutane sama da 60
2. yara ‘yan kasa da shekara 12
3. mutanen da a koyaushe suna fuskantar wahalar motsa jiki.

Akwai haɗari mai haɗari daga ɗaukar Siofor, wannan lactic acidosis ne. Wannan halin yana buƙatar asibiti na gaggawa da magani a cikin yanayin kulawa mai zurfi.

Lactic acidosis yana da alamun bayyanar:

• saukar da zazzabi a zazzabi,
• jinkirin bugun zuciya
• gazawar numfashi
• zuciya tashin hankali,
• rauni da nutsuwa,
• sauke cikin karfin jini.

Daga Siofor akwai tasirin sakamako waɗanda ke ƙaruwa bayan ƙarfin motsa jiki. Yin watsi da wannan gaskiyar, mata da yawa sun fara shan maganin don asarar nauyi, suna haɗuwa da liyafa tare da lodi a cikin dakin motsa jiki ko wurin waha. Don haka, ana tsammanin sakamako baya faruwa.

Saboda rashin amfani da Siofor, tunani mara kyau ya tashi game da miyagun ƙwayoyi.

Hakanan ya kamata a lura da cewa yiwuwar lactic acidosis yana ƙaruwa idan kun sha giya.

Siofor don rigakafin kamuwa da ciwon sukari na 2

Don hana samuwar nau'in ciwon sukari na 2, yana da mahimmanci koyaushe ku bi yanayin rayuwa lafiya. Don haka, ya kamata ku ƙara yawan aikinku kuma ku canza tsarin abincinku.

Yawancin marasa lafiya a rayuwar yau da kullun sun fi son kar su bi shawarar rayuwa. Batun kirkiro da dabarun rigakafi don kamuwa da cututtukan type 2 tare da yin amfani da Siofor babban lamari ne.

Shekaru 10 da suka gabata, shawarwari daga Americanungiyar Ciwon Ciki na Amurka game da amfani da Siofor don rigakafin rigakafin kamuwa da cutar sankara ya bayyana. Nazarin ilimin kimiyya ya wuce shekaru uku, godiya gareshi ya zama sananne cewa yin amfani da Glucophage ko Siofor yana rage yiwuwar haifar da cutar da kashi 31%.

Idan mutum ya sauya gaba daya zuwa rayuwa mai kyau, to wannan hadarin zai fada da kashi 58%. Samun allunan kwayoyin metformin a matsayin matakan kariya don bada shawarar ga marasa lafiya da ke da matukar haɗarin kamuwa da ciwon sukari.

Wannan rukunin ya haɗa da mutanen da ba su da shekaru 60 waɗanda ba su da nauyi, waɗanda ƙari kuma suna da dalilai masu haɗari guda ɗaya ko ƙari, sune:

1. glycated haemoglobin - fiye da 6%,
2. hauhawar jini
3. rage girma cholesterol a cikin jini,
4. babban triglycerides,
5. nau'in ciwon sukari na 2 a cikin dangi na kusa,
6. bayanin jikin mutum sama da 35.

Irin waɗannan marasa lafiya na iya ɗaukar Siofor don hana ciwon sukari. Sashi a cikin wannan yanayin yana daga 250 zuwa 850 MG sau biyu a rana. A halin yanzu, Siofor ko mai bambanta, miyagun ƙwayoyi Glucofage shine kawai magani wanda ake la'akari da shi azaman prophylactic game da ciwon sukari.

Kiyaye ƙarƙashin ikon aikin kodan da hanta yakamata ya kasance kafin lokacin sanya kuɗi tare da metformin sannan kuma kowane watanni shida. Bugu da kari, yana da muhimmanci a duba matakan lactate na jini sau biyu a shekara. A cikin lura da ciwon sukari mellitus tare da haɗuwa da Siofor tare da abubuwan da aka samo na sulfonylurea, babban yiwuwar hypoglycemia ya bayyana.

Ana buƙatar saka idanu akan matakan sukari na jini, har zuwa sau da yawa a rana. Sakamakon haɗarin hypoglycemia a cikin marasa lafiya waɗanda ke ɗaukar Glucofage 850 ko Siofor, ba a ba da shawarar yin ayyukan da ke buƙatar karɓar kulawa da kuma mummunan halayen psychomotor.

A halin yanzu, farashin maganin yana bambanta dangane da sashi. A matsayinka na mai mulkin, kunshin Siofor 850 farashin kimanin 350 rubles.

Gwanaye game da bidiyon a wannan labarin zai faɗi game da wakili na hypoglycemic wakilin Siofor.

Yara masu shekaru 10-18

Matsakaicin matakin farko lokacin amfani da Siofor azaman monotherapy ko a hade tare da insulin shine lokaci 1 a rana, 500 ko 850 mg.

Bayan kwanaki 10-15 daga fara shan Siofor, ana iya ƙara yawan kashi a hankali, gwargwadon alamun alamun glucose jini. Increaseara yawanta a hankali yana rage yiwuwar tasirin sakamako daga hanji.

Matsakaicin - 2000 MG kowace rana a cikin kashi 2-3.

Matsayin insulin an ƙaddara shi ne akan maida hankali akan glucose a cikin jini.