Tsari sashi: Allunan mai rufe fim 1 kwamfutar hannu mai rufe jiki ya ƙunshi: Sashi 2.5 MG + 500 MG: Aiki mai aiki: glibenclamide - 2.5 MG, metformin hydrochloride - 500 MG. Kernel: sodium croscarmellose - 14.0 mg, povidone K 30 - 20,0 mg, microcrystalline cellulose - 56.5 mg, magnesium stearate - 7.0 mg. Harsashi: opadry OY-L-24808 ruwan hoda - 12.0 mg: lactose monohydrate - 36,0%, hypromellose 15cP - 28,0%, titanium dioxide - 24.39%, macrogol - 10.00%, baƙin ƙarfe baƙin ƙarfe, 1, 30%, baƙin ƙarfe oxide - 0.3%, baƙin ƙarfe baƙin ƙarfe - 0.010%, tsarkakakken ruwa - qs Sashi 5 MG + 500 MG: Aiki mai aiki: glibenclamide - 5 MG, metformin hydrochloride - 500 MG. Kernel: sodium croscarmellose - 14.0 mg, povidone K 30 - 20,0 mg, microcrystalline cellulose - 54,0 mg, magnesium stearate - 7.0 mg. Harsashi: Opadry 31-F-22700 rawaya - 12.0 mg: lactose monohydrate - 36,0%, hypromellose 15 cP - 28,0%, titanium dioxide - 20.42%, macrogol - 10.00%, fenti quinoline rawaya - 3 , 00%, baƙin ƙarfe oxide - 2.50%, baƙin ƙarfe oxide - 0.08%, tsarkakakken ruwa - qs. Bayanin
Sashi 2.5 MG + 500 MG: Allunan biconvex mai kwalliya, mai hade da murfin fim na launin ruwan orange, tare da zanen “2.5” a gefe guda.
Sashi 5 MG + 500 MG: Allunan biconvex mai kwalliya, mai hade da launin rawaya fim, tare da zane "5" a gefe guda. Kayan magungunaGlucovans ® wani hadadden haɗuwa ne na wakilai na jini guda biyu na ƙungiyoyin magunguna daban-daban: metformin da glibenclamide. Metformin yana cikin rukunin biguanides kuma yana rage yawan abubuwan glual da na postprandial a cikin jini. Metformin baya motsa insulin insulin kuma sabili da haka baya haifar da ƙwanƙwasa jini. Yana da matakai 3 na aikin: yana rage haɓakar glucose ta hanta ta hana gluconeogenesis da glycogenolysis,yana ƙara haɓakar jiɓin masu karɓa zuwa insulin, yawan amfani da amfani da glucose ta sel a cikin tsokoki,yana jinkirta ɗaukar glucose a cikin ƙwayar ciki.Har ila yau, maganin yana da tasiri mai amfani akan abubuwan da ke cikin jini, rage matakin jimlar cholesterol, ƙarancin lipoproteins (LDL) da triglycerides. Metformin da glibenclamide suna da matakai daban-daban na aiwatarwa, amma tare da jituwa tare da juna kan ayyukan hypoglycemic. Haɗin haɗakar abubuwa biyu na jini yana da tasirin aiki don rage glucose. PharmacokineticsGlibenclamide. Lokacin ɗauka ta baka, ɗaukar ƙwayar gastrointestinal ya fi 95%. Glibenclamide, wanda shine ɓangare na miyagun ƙwayoyi Glucovans® micronized ne. Matsakaicin taro a cikin plasma an kai shi a cikin awanni 4, girman rarraba shine kusan lita 10. Sadarwa tare da sunadaran plasma kashi 99%. An kusan kusan metabolized a cikin hanta tare da samuwar metabolites guda biyu marasa aiki, wadanda kodan ke cirewa (40%) kuma da bile (60%). Cire rabin rayuwar shine daga awa 4 zuwa 11. Metformin bayan gudanar da baki, yana narkewa daga jijiyoyin ciki sosai, an sami mafi girman hankali a cikin plasma a cikin awa 2.5. Kimanin 20-30% na metformin an kebe ta ta cikin jijiyoyi ba su canzawa. Cikakken bayanin halitta daga 50 zuwa 60%. An rarraba Metformin cikin hanzari a cikin kyallen takarda, kusan ba a ɗaura shi ga furotin plasma ba. Yana cikin metabolized sosai ga rauni sosai kuma kodan ya keɓe shi. Cire rabin rabin rayuwa shine kimanin awa 6.5. Idan akwai rauni na aiki koda, toshewar koda ya ragu, kamar yadda shikanin creatinine yake, yayin kawarda rabin rayuwa yana ƙaruwa, wanda hakan yakan haifar da ƙaruwa da haɓakar metformin a cikin jini na jini. Haɗin metformin da glibenclamide a cikin tsari iri ɗaya suna da daidai iri ɗaya kamar lokacin ɗaukar allunan da ke ɗauke da metformin ko glibenclamide a cikin keɓance. Rashin abinci na metformin a hade tare da glibenclamide ba shi da matsala ta hanyar abinci, kazalika da bioavailability na glibenclamide. Koyaya, yawan shan glibenclamide yana ƙaruwa tare da ɗimbin abinci. Alamu don amfani:
Type 2 ciwon sukari a cikin manya:
tare da rashin ingancin maganin abinci, motsa jiki na jiki da monotherapy na baya tare da metformin ko abubuwan da suka samo asali na sulfonylurea,don maye gurbin maganin da ya gabata tare da kwayoyi guda biyu (metformin da abubuwan da aka samo na sulfonylurea) a cikin marasa lafiya tare da tsayayyen tsari mai kyau na glycemia.Yarjejeniyar:tashin hankali ga metformin, glibenclamide ko wasu abubuwan da suka samo asali na sulfonylurea, gami da abubuwan taimako,nau'in ciwon sukari guda 1fida mai fama da ciwon sukari,gazawar koda ko gajiya aiki aikin na kasa (kerawa kasa da mil 60 / min),matsanancin yanayi wanda zai iya haifar da canji a cikin aikin koda: bushewar fata, matsanancin ciwo, girgiza, gudanarwar cikin ciki na abubuwan aidin (dauke da "Instididdigar Musamman"),m ko rashin lafiya cututtuka da ke hade da nama hypoxia: zuciya ko na numfashi kasawa, kwanan nan na myocardial infarction, gigice,gazawar hantaporfriaciki, shayarwa,amfani da miconazole,babban tiyatana kullum mai shan barasa, m shan giya,lactic acidosis (gami da tarihi),biye da tsarin karancin kalori (kasa da adadin kuzari 1000 / rana),Ba'a ba da shawarar yin amfani da miyagun ƙwayoyi a cikin mutanen da suka haura shekaru 60 waɗanda ke yin aiki na zahiri, wanda ke da alaƙa da haɓakar haɗarin haɓakar lactic acidosis a cikinsu. Glucovans ® ya ƙunshi lactose, sabili da haka ba a ba da shawarar amfani da shi ga marasa lafiya da cututtukan cututtukan da ke da alaƙa da ke haɗuwa da rashin haƙuri na galactose, rashi lactase ko glucose-galactose malabsorption syndrome. Tare da kulawa: febrile ciwo, adrenal insufficiency, hauhawar jini na na baya pituitary, thyroid cuta tare da uncompensated take hakkin da aikin. Yi amfani da lokacin daukar ciki da lokacin shayarwa
Yin amfani da maganin yana contraindicated lokacin daukar ciki. Yakamata a gargadi mara lafiya cewa yayin jiyya tare da Glucovans is ya zama dole a sanar da likita game da shirin da aka shirya ciki da kuma farawar ciki. Lokacin da ake shirin yin ciki, da kuma lokacin da ake yin ciki yayin lokacin shan Glucovans drug, yakamata a dakatar da magungunan, kuma an tsara maganin insulin. Glucovans ® yana cikin garkuwar nono, domin babu wata hujja game da iyawarta ta shiga cikin madara. Sashi da gudanarwaAdadin maganin yana maganin likita ne daban-daban ga kowane mara lafiya, gwargwadon matakin glycemia. Maganin farko shine 1 kwamfutar hannu na miyagun ƙwayoyi Glucovans ® 2.5 mg + 500 mg ko Glucovans mg 5 mg + 500 mg sau ɗaya a rana. Don guje wa hypoglycemia, kashi na farko kada ya wuce kashi na yau da kullun na glibenclamide (ko kuma daidai gwargwado na wani maganin da aka ɗauka a baya wanda aka riga aka ɗauka da maganin sulfonylurea) ko metformin, idan aka yi amfani dashi azaman maganin farko. Ana ba da shawarar kashi ɗaya ta ƙaranci 5 na glibenclamide + 500 MG na metformin kowace rana a cikin makwanni 2 ko fiye don cimma cikakken iko na glucose jini. Canji magani na hade hade tare da metformin da glibenclamide: kashi na farko kada ya wuce kashi na yau da kullun na glibenclamide (ko kuma daidai gwargwado na wani shirin sulfonylurea) da metformin da aka ɗauka a baya. Kowane makonni 2 ko fiye bayan fara magani, ana daidaita sashi gwargwadon matakin glycemia. Matsakaicin adadin yau da kullun shine allunan 4 na miyagun ƙwayoyi Glucovans ® 5 mg + 500 MG ko allunan 6 na miyagun ƙwayoyi Glucovans ® 2.5 mg + 500 mg. Sashen lokaci:
Jadawalin tsari ya dogara da manufar mutum ɗaya: Don sashi na 2.5 mg + 500 MG da 5 MG + 500 MG Sau ɗaya a rana, da safe yayin karin kumallo, tare da alƙawarin kwamfutar hannu 1 a kowace rana.Sau biyu a rana, safe da maraice, tare da alƙawarin allunan 2 ko 4 a rana.Don sashi na 2.5 mg + 500 MG Sau uku a rana, da safe, yamma da yamma, tare da alƙawarin 3, 5 ko 6 allunan a rana. Don sashi na 5 MG + 500 MG Sau uku a rana, da safe, yamma da yamma, tare da alƙawarin Allunan 3 a rana. Allunan ya kamata a ɗauka tare da abinci. Ya kamata kowane abinci ya kasance tare da abinci tare da isasshen abun da ke cikin carbohydrate don hana hypoglycemia. Tsofaffi marasa lafiya
An zaɓi kashi na miyagun ƙwayoyi dangane da yanayin aikin koda. Kashi na farko bai kamata ya wuce kwamfutar hannu 1 na magani Glukovans ® 2.5 mg + 500 mg. Yin nazari akai-akai na aikin koda ya zama dole. Yara
Ba'a bada shawarar Glucovans ® don amfani da yara ba. Side effectsAbubuwanda zasu biyo baya na iya faruwa yayin jiyya tare da Glucovans ®. An kiyasta yawan tasirin magungunan kamar haka:
Sau da yawa sosai: ≥ 1/10
Akai-akai: ≥ 1/100, ® ya kamata a daina. An ba da shawarar yin magani bayan sa'o'i 48, kuma bayan an tantance aikin ƙididdigar kuma an gane shi al'ada. Aikin koda
Tunda metformin yana cire kodan, kuma a kai a kai bayan hakan, ya zama dole a tantance keɓancewar halittar mahaifa da / ko kuma keɓaɓɓiyar sinadarin halittu: aƙalla sau ɗaya a shekara a cikin marasa lafiya da ke da aikin na al'ada, kuma sau 2-4 a shekara a cikin tsofaffi marasa lafiya. , kamar yadda kuma a cikin marasa lafiya tare da keɓancewar creatinine a saman iyakar al'ada. Ana bada shawarar yin taka tsantsan a lokuta inda aikin koda zai iya zama mai rauni, alal misali, a cikin tsofaffi marassa lafiya, ko kuma batun farawar antihypertensive therapy, yin amfani da diuretics ko magungunan anti-inflammatory marasa amfani (NSAIDs). Sauran kiyayewa
Mai haƙuri dole ne ya sanar da likita game da bayyanar kamuwa da cututtukan bronchopulmonary ko wata cuta mai rarrafe ta gabobin ƙwayoyin cuta. Tasiri kan iya tuƙin mota da aiki tare da kayan aiki
Yakamata a sanar da mara lafiyar game da hadarin cututtukan hypoglycemia kuma ya kamata su kiyaye matakan kulawa yayin tuki da aiki tare da hanyoyin da ke buƙatar karuwar hankali da saurin halayen psychomotor. Mai masana'antaMERC SANTE SAAS
MERCK SANTE s.a.s. Adireshin shari'a:
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37 rue Saint Romain, 69379 LYON CEDEX 08, Faransa Adireshin yanar gizon:
Centre de Production SEMOIS, 2 rue du Pressoire Ver, 45400 SEMOIS, Faransa
Centre de Production SEMOY, 2 rue du Pressoir Vert, 45400 SEMOY, Faransa Yakamata a aika da bukatar da masu amfani da su zuwa:
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Adireshin Intanet: www.nycomed.ru Likita mai maganin Vasilieva E.I. ya tabbatar da bayanan da ke shafin. Labari mai ban sha'awaYadda zaka zabi analog ɗin da ya dace
A fannin ilimin magunguna, yawanci ana rarraba magunguna zuwa maganganu da analogues. Tsarin kalmomin sun hada da ɗaya ko fiye da waɗannan ƙwayoyin aiki guda ɗaya waɗanda ke da tasirin warkewa akan jiki. Ta hanyar analogs ana nufin magunguna waɗanda ke ɗauke da abubuwa daban-daban na aiki, amma anyi nufin maganin cututtukan guda ɗaya. Bambanci tsakanin kamuwa da kwayar cuta da kwayan cuta
Kwayoyin cuta suna haifar da ƙwayoyin cuta, ƙwayoyin cuta, fungi da protozoa. Halin cututtukan da ƙwayoyin cuta da ƙwayoyin cuta ke haifar da irin wannan. Koyaya, don bambance abin da ke haifar da cutar yana nufin zaɓin madaidaiciyar magani wanda zai taimaka wajan magance wuyar cutar da sauri kuma ba zai cutar da yaron ba. Cutar rashin lafiyan shine sanadiyyar yawan sanyi
Wasu mutane sun saba da yanayin da yaro sau da yawa kuma na dogon lokaci yana fama da mura. Iyaye suna kai shi wurin likitoci, yin gwaje-gwaje, shan kwayoyi, kuma a sakamakon haka, an riga an yi wa yaro rajista tare da likitan yara kamar yadda ba shi da lafiya. Ba a gano gaskiyar abubuwan da ke haifar da cututtukan numfashi ba. Urology: lura da chlamydial urethritis
Chlamydial urethritis yawanci ana samun sa a cikin aikin masanin ilimin urologist. An haifar da shi ta hanyar Chlamidia trachomatis mai aiki da jijiya ta intracellular, wanda ke da kaddarorin ƙwayoyin cuta da ƙwayoyin cuta, wanda yawanci yana buƙatar jigilar maganin rigakafi na dogon lokaci don maganin rigakafi. Yana da ikon haifar da cutar kumburin da ba takamaiman kumburin ciki ba a cikin maza da mata.
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