Lantus Solostar (alkalami sirinji) - insulin aiki na tsawon lokaci

Muna ba ku karanta labarin a kan taken: "insulin lantus solostar" tare da sharhi daga kwararru. Idan kana son yin tambaya ko rubuta ra'ayi, zaka iya yin wannan a ƙasa, bayan labarin. Kwararrun masanan ilimin likitancin mu zasuyi muku amsar.

Lantus shine ɗayan farkon rashin lafiyar analogues na insulin ɗan adam. An samo shi ta hanyar maye gurbin amino acid asparagine tare da glycine a matsayi na 21 na sarkar A kuma ƙara amino acid arginine biyu a cikin sarkar B zuwa tashar amino acid ɗin. Wannan magungunan an samar dashi ne ta babban kamfanin samar da magunguna na Faransa - Sanofi-Aventis. A yayin binciken da yawa, an tabbatar da cewa insulin Lantus ba wai kawai yana rage haɗarin hypoglycemia ba idan aka kwatanta da magungunan NPH, amma yana inganta haɓakar metabolism. Da ke ƙasa akwai taƙaitaccen umarnin don amfani da sake dubawa game da masu ciwon sukari.

Abunda yake aiki na Lantus shine insulin glargine. An samo shi ta hanyar sake haifuwa ta amfani da ƙwayar k-12 na ƙwayar ƙwayar cuta ta Escherichia coli. A cikin yanayin tsaka tsaki, ya zama mai narkewa kaɗan, a cikin matsakaic acidic ya narke tare da ƙirƙirar microprecipitate, wanda a hankali a hankali yake kwantar da insulin. Sakamakon wannan, Lantus yana da tsarin ayyukan aiwatar da ingantaccen aiki wanda ya kasance har zuwa awanni 24.

Babban kayan magunguna:

• Sannu a hankali adsorption da kuma cikakken bayanin martaba cikin awa 24.
• Ressionarfafa garkuwar garkuwar jiki da narkewa a cikin tsopocytes.
• Abubuwan da ke aiki suna ɗaure wa masu karɓa na insulin sau 5-8 da ƙarfi.
• Gua'idar aikin glucose na metabolism, hanawar samuwar glucose a cikin hanta.

A cikin 1 ml Lantus Solostar ya ƙunshi:

• 3.6378 MG na insulin glargine (dangane da 100 IU na insulin mutum),
• 85% glycerol
• ruwa don yin allura
• hydrochloric maida hankali ne acid,
• m-cresol da sodium hydroxide.

Lantus - maganin zazzage don allurar sc, ana samun su ta hanyar:

• kwantena na tsarin OptiKlik (5pcs a kowace fakiti),
• 5 aljihunan alkalami Lantus Solostar,
• Alkalami guda biyu na optiSet a cikin kunshin guda 5 guda 5. (mataki na 2 raka'a),
• 10 ml vials (raka'a 1000 a cikin ruwa guda).

1. Manya da yara daga shekara 2 da ciwon sukari na 1.
2. Nau'in nau'in ciwon sukari na 2 (dangane da rashin ingancin allunan).

A cikin kiba, haɗakar magani yana da tasiri - Lantus Solostar da Metformin.

Akwai magungunan da ke shafar metabolism, yayin da suke ƙaruwa ko rage buƙatar insulin.

Rage sukari: wakilan maganin antidiabetic, sulfonamides, ACE inhibitors, salicylates, angioprotectors, monoamine oxidase inhibitors, antiarrhythmic dysopyramides, narcotic analgesics.

Sugarara yawan sukari: hodar iblis na thyroid, diuretics, juyayi, ƙwarin hana baki, abubuwan gado na phenothiazine, abubuwan hana kariya.

Wasu abubuwa suna da tasirin hypoglycemic duka da tasirin hyperglycemic. Wadannan sun hada da:

• beta blockers da lithium salts,
• barasa
• Clonidine (maganin hana cin jini).

1. Haramun ne a yi amfani da shi a cikin marassa lafiyar da ke da haqurin insulin glargine ko abubuwan taimako.
2. Hypoglycemia.
3. Jiyya na ketoacidosis na ciwon sukari.
4. Yara ‘yan kasa da shekaru 2.

Matsalar da za a iya yi da da wuya ta faru, umarnin sun faɗi cewa:

• lipoatrophy ko lipohypertrophy,
• rashin lafiyan halayen (edema na Quincke, rawar jiki, fitsari),
• ciwon tsoka da jinkirtawa a jikin ion sodium ion,
• dysgeusia da rauni na gani.

Idan mai ciwon sukari yayi amfani da matsakaiciyar matsakaiciyar matsakaici, to idan aka canza zuwa Lantus, za'a canza sashi da tsarin maganin. Canjin insulin yakamata ayi a asibiti kawai.

A nan gaba, likita yana duban sukari, salon mai haƙuri, nauyi da daidaita adadin raka'a ana gudanarwa. Bayan watanni uku, za a iya bincika tasirin maganin da aka tsara ta hanyar bincika glycated haemoglobin.

Umarni akan bidiyo:

A Rasha, duk masu ciwon sukari masu dogaro da kai sun canza shi daga Lantus zuwa Tujeo. Dangane da bincike, sabon maganin yana da ƙananan haɗarin haɓakar haɓakar jini, amma a aikace yawancin mutane suna korafi cewa bayan sun juya zuwa Tujeo, ƙanshinsu ya yi tsalle sosai, don haka ana tilasta su sayi insulin Lantus Solostar da kansu.

Levemir ingantaccen magani ne, amma yana da kayan aiki daban, kodayake tsawon lokacin aiki shima awowi 24 ne.

Aylar bai gamu da insulin ba, umarnin ya ce Lantus iri daya ne, amma masana'anta sun fi araha.

Ba a gudanar da karatun ɗabi'a na Lantus tare da mata masu juna biyu. A cewar bayanan da ba a sani ba, maganin ba ya cutar da hanyar daukar ciki da yaran da kansa.

An gudanar da gwaje-gwajen ne akan dabbobi, lokacin da aka tabbatar da cewa insulin glargine bashi da sakamako mai guba kan aikin haihuwa.

Ana iya tsara Lantus Solostar mai juna biyu idan insulin NPH yana aiki. Iyaye mata masu zuwa yakamata su lura da sukarin su, saboda a cikin farkon farkon, bukatar insulin na iya raguwa, kuma a cikin na biyu da na uku.

Kada ku ji tsoron shayar da jariri nono; umarnin ba su da bayanin da Lantus zai iya shigar da shi cikin madara.

Rayuwar shiryayye na Lantus shine shekaru 3. Kuna buƙatar adanawa a cikin duhu mai duhu daga kariya daga hasken rana a zazzabi na 2 zuwa 8. Yawancin lokaci wurin da ya fi dacewa shine firiji. A wannan yanayin, tabbatar da duba tsarin zafin jiki, saboda haramcin insulin Lantus ne haramtacce!

Tun da amfani na farko, ana iya adana miyagun ƙwayoyi na tsawon wata guda a wuri mai duhu a zazzabi da bai wuce digiri 25 (ba a cikin firiji). Karka yi amfani da insulin da ya ƙare.

An bayar da maganin Lantus Solostar kyauta ta magani ta hanyar likitancin endocrinologist. Amma kuma yana faruwa da mai ciwon sukari ya sayi wannan magani a kashin kansa a kantin magani. Matsakaicin farashin insulin shine 3300 rubles. A cikin Ukraine, za'a iya sayan Lantus na 1200 UAH.

Masu ciwon sukari sun ce yana da insulin gaske sosai, cewa ana sanya sukarin su cikin iyaka. Ga abin da mutane ke faɗi game da Lantus:

Yawancin hagu kawai masu bita ne kawai. Mutane da yawa sun ce Levemir ko Tresiba ya fi dacewa da su.

Tare da ciwon sukari, ana tilasta wa mutane sake cika matakin insulin a jiki ta hanyar allura. Istswararrun masana sun kirkiro magunguna waɗanda aka samo ta hanyar jigidar halittar DNA. Godiya ga wannan, ƙwayar Lantus Solostar ta zama analog mai tasiri na insulin ɗan adam. Wannan magani yana ba ku damar sarrafa adadin glucose a cikin jikin mutum don tabbatar da ayyuka masu mahimmanci.

Wannan maganin ya dace don amfani, saboda yana samuwa a cikin nau'in sikirin-pen, wanda zai ba ka damar yin injections da kanka. Kuna buƙatar sarrafa magani a ƙarƙashin fata a cikin ciki, cinya ko kafada. Yin allura wajibi ne sau ɗaya a rana. Amma game da sashi, ya kamata a wajabta shi ta halartar likita, bisa ga bayyanar cututtuka da kuma hanyar cutar.

Hakanan an haɗa Lantus Solostar tare da wasu kwayoyi waɗanda ke taimakawa sake cika matakan sukari a cikin masu ciwon sukari na 2. Koyaya, ya zama dole a hankali yin nazarin rashin jituwa na wannan maganin tare da wasu.

Magungunan ya ƙunshi glargine insulin. Bugu da kari: ruwa, glycerol, acid (hydrochloric), sodium hydroxide da m-cresol. Cartayan katako ɗaya ya ƙunshi 3 ml. mafita.

Strengtharfafa da bayanin martaba na insulin glargine suna kama da ɗan adam, sabili da haka, bayan gudanarwarsa, glucose metabolism ya faru, kuma hankali ya ragu. Hakanan, wannan kayan yana taimakawa haɓaka aikin furotin, yana hana lipolysis da kariya a cikin adipocytes.

Ayyukan irin wannan insulin ya fi tsayi, amma duk da gaskiyar cewa ci gaba yana faruwa a hankali sosai. Hakanan a kan tsawon lokacin da miyagun ƙwayoyi yana da tasirin halaye na mutum, salon rayuwa.

Nazarin sun ƙaddara cewa glargine insulin ba ya haifar da ciwon sukari mai ciwon sukari.

A cikin sarari tsaka tsaki, insulin ya zama mai narkewa kaɗan. A cikin acidic, microprecipitate ya bayyana, yana sake shi, don haka an tsara tsawon lokacin maganin har tsawon awanni 24. Game da babban kayan aikin magunguna, yana da cikakken martaba da kuma jinkirin adsorption.

Ofasar asalin wannan maganin shine Faransa (Kamfanin Sanofi-Aventis). Koyaya, kamfanonin masana'antun magunguna da yawa a Rasha suma suna tsunduma cikin siyarwa da kuma samar da magunguna dangane da cigaban mallaka.

Lantus Solostar yakamata a gudanar dashi ƙarƙashin abu. Wajibi ne a ƙayyade takamaiman lokaci don gudanar da magani a kai a kai ta awa. Kwararrun yakamata ya lissafa kashi, bisa nazari da gwaje-gwaje. Ana amfani da miyagun ƙwayoyi a ɓangarorin aikin, sabanin sauran magunguna.

Kuna iya amfani da maganin don mutanen da ke da nau'in ciwon sukari na biyu. An ba da izinin amfani dashi tare da abubuwan hypoglycemic.

Motsa jiki ga wannan magani tare da waɗanda ke da matsakaita ko na tsawon lokaci, yana da mahimmanci don canza sashi da lokacin amfani. Don rage haɗarin cutar hypoglycemia da dare, yana da kyau a rinka rage yawan suturu yayin sauyawa zuwa wannan insulin. A wasu halaye, mutum na iya haɓaka ƙwayoyin rigakafi, kuma amsawar maganin zai iya raguwa. Don yin wannan, kuna buƙatar daidaita sashi a kai a kai kuma ku kula da matakin glucose.

Ka’idojin gudanar da magunguna:

• Shigar kawai a cikin murfin jin dadi (ciki, cinya, kafada).
• An bada shawara don canza wuraren allura don guje wa bayyanar hematomas ko tasirin ciwo.
• Kar a yi allurar cikin ciki.
• Hakanan, masana sun hana hada wannan magani da sauran magunguna.
• Kafin fara allurar, cire kumfa daga cikin akwati kuma ɗaukar sabon allura.

Tun da ana sayar da magani a cikin nau'in alkalami na sirinji, dole ne a bincika shi sosai kafin allurar don babu wasu wuraren girgije a cikin maganin. Idan akwai laka, to ana ganin maganin bai dace ba kuma ba shi da aminci don amfani. Bayan amfani da alkairin sirinji, dole ne a zubar dashi. Hakanan ya kamata ku tuna cewa wannan magungunan ba za a iya tura shi ga wasu mutane ba.

Game da lissafin sashi, to, kamar yadda aka ambata a sama, ƙwararren masani ne ya kamata ya shigar da shi. Magungunan da kansa zai baka damar yin kashi 1 zuwa 80 raka'a. Idan allura tare da kashi fiye da 80 raka'a wajibi ne, ana yin allura biyu.

Kafin allurar, dole ne a bincika alkairin sirinji. Don yin wannan, algorithm na ayyuka ana yin su:

• Alamar tantancewa.
• Kimantawar bayyanar.
• Ana cire murfin, yana ɗaukar allura (ba a karkata ba).
• Sanya sirinji tare da allura sama (bayan an auna kashi 2 na U U).
• Matsa akan katun, danna maɓallin shigarwar duk hanyar.
• Binciki yawan saukowar insulin a ƙarshen allura.

Idan lokacin insulin gwajin farko bai bayyana ba, ana sake maimaita gwajin har sai mafita ta bayyana bayan latsa maɓallin.

Babban sakamako na gefen da zai iya haifar da Lantus Solostaom shine bayyanar cututtukan hypoglycemia. Tare da yawan wucewa ko canji a lokacin cin abinci, canji a cikin adadin glucose yana faruwa, wanda ke haifar da wannan rikitarwa. Sakamakon rashin lafiyar hypoglycemia, mutum na iya haɓaka rikicewar jijiyoyin jini.

Bugu da kari, kan amfanin amfani da maganin, alamomin masu zuwa na iya bayyana:

• Matsaloli tare da tsarin juyayi (retinopathy, dysgeusia, raunin gani).
• Lipoatrophy, lipodystrophy.
• Allergy (antima neurotic edema, bronchospasm).
• Bronchospasm.
• Harshen Quincke's edema.
• Ciwan tsoka.
• Kumburi da kumburi bayan allura.

Idan ana gudanar da adadin ƙwayar cuta mai yawa, to ba za'a iya magance cutar ta glycemia ba. A wannan yanayin, mutum na iya fuskantar alamun bayyanar:

• Ciwon kai.
• Gajiya
• Gajiya.
• Matsalolin hangen nesa, daidaituwa, daidaituwa a sarari.

Wadannan alamomin da suka gabata zasu iya faruwa: yunwar, haushi, damuwa, gumi mai sanyi, bugun zuciya.

A wurin allurar, lipodystrophy na iya bayyana, wanda zai kawo saurin aiwatar da shan ƙwayoyi. Don kauce wa wannan, ya zama dole don canja wurin allurar, madadin cinya, kafada da ciki. Bugu da kari, wuraren hakori, ja, da zafi na iya faruwa a wuraren fatar. Koyaya, cikin yan kwanaki waɗannan matsalolin zasu iya ɓacewa.

Kamar kowane magani, Lantus SoloStar insulin Lantus SoloStar yana da contraindications don amfani, wanda gwargwadon maganin bai kamata a sha shi ba:

• Mutanen da ke nuna rashin damuwa ga magani.
• Tare da rashin yarda na mutum zuwa abubuwan da ke cikin miyagun ƙwayoyi.
• Don matsaloli tare da hanta ko koda.
• Yara ‘yan kasa da shekaru 6.
• Tare da ketoacidosis.
• Tsofaffi mutanen da suka sami rauni koda ko aikin hanta.
• Marasa lafiya tare da ƙwayar cerebral.

Dangane da nazarin asibiti, babu wasu sakamako masu illa yayin amfani da wannan magani yayin daukar ciki. Magungunan ba shi da mummunar tasiri ga uwa da ɗa.

Likita na iya yin maganin Lantus SoloStar idan insulin NPH bashi da tasirin da ake so. Wajibi ne a lura da matakin sukari na jinin mace mai ciki musamman a hankali, tunda a cikin lokuta daban-daban alamomin sa na iya canzawa. A farkon, yawanci suna ƙasa da na biyu da na uku. Hakanan, tare da irin wannan ƙwayar cuta, zaku iya shayarwa ba tare da tsoron rikice-rikice da illa ba.

Yin hulɗa tare da wasu kwayoyi

Magungunan Lantus Solostar yana da ikon canzawa dangane da maganin da aka haɗa shi. Wadannan sun hada da:

• hanawar
• maganin antidiabetic magunguna
• kwayoyin kara kuzari,
• sulfanimamides,
• wakili
• rashin biyayya
• Glarinin.

A hade tare da magungunan corticosteroid, Lantus SoloStara yana da ingancin maganin shayarwa. Waɗannan sun haɗa da: danazol, isoniazid, diazoxide, diuretics, estrogens.

Don rage ko ƙarfin tasirin Lantus na iya saltsin salhi, giya ethyl, pentamidine, clonidine.

Idan wani abin sama da ya faru ya faru, ya zama dole a dakatar da yawan zubar jini tare da taimakon kayayyakin da ke dauke da sinadarin carbohydrates mai saurin daukar hankali. Lokacin da mummunan yanayin hypoglycemia ya faru, dole ne a shigar da glucagon a cikin tsokoki ko a cikin fata ko glucose a cikin jijiya.

Sanadin yawan shan kwayoyi ya yi yawa sosai na maganin. A wannan yanayin, yana da mahimmanci a nemi likita don gudanar da maimaita gwaje-gwaje da kuma kafa sabon kashi na shan ƙwayoyi.

Lokacin dakatar da hypoglycemia, ba za ku iya barin mara haƙuri a cikin kulawa ba, tunda ana iya maimaita hare-hare yayin rana. Yana da matukar muhimmanci a sanya ido a kai a kai, motsa jiki akai-akai, kar a tsallake abinci, kar a ci abinci da aka haramta. Dangane da cutar sankarau, ya kamata mutane su sanya ido sosai a kan yanayin su, ta yadda idan ya zama tilas neman taimako nan da nan.

Yanayin ajiya na miyagun ƙwayoyi an iyakance zuwa shekaru uku, ƙarƙashin yanayin zafin jiki na har zuwa digiri 8. Karka sanya allurar sirinji a wuraren da yara zasu iya hawa. Zai fi kyau a adana ƙwayar a cikin firiji don kula da yawan zafin jiki da ya dace. Koyaya, yana da kyau a tuna cewa baza ku iya kiyaye insulin a cikin injin daskarewa ba.

Ana iya amfani da alkalami na syringe bayan allurar farko ta kwanaki 28. Bayan an yi allura, ba shi yiwuwa a adana maganin a cikin firiji. Yana da kyau cewa tsarin zafin jiki bai wuce digiri 25 ba. An hana amfani da magunguna da aka kare.

Yawancin marasa lafiya waɗanda suka riga sun yi ƙoƙari kuma suna samun sakamakon amfani da wannan magani sun gamsu, saboda yana taimakawa ci gaba da sukari tsakanin iyakoki na yau da kullun.

Koyaya, ba kowa ba ne da farko ya yi nasara wajen gudanar da maganin ba tare da ɓacin rai ba, saboda haka, kafin allurar, ya wajaba a bincika duk shawarar da mai ƙira ke bayarwa don amfani.

Ana ba marasa lafiya da masu fama da cutar siga Lantus SoloStar kyauta, kamar yadda likitancin endocrinologist ya tsara shi bisa ga takardar sayen magani. A wasu halaye, dole ne ku sayi maganin ku. A wannan yanayin, babu matsaloli, tunda ana sayar da shi a kantin magani a cikin alkalam. Matsakaicin farashin maganin yana kusan 3 500 rubles, kuma a cikin Ukraine kusan 1300 hryvnia.

Akwai isasshen analogues waɗanda suke da abubuwa iri ɗaya a cikin abun da ke ciki, amma a lokaci guda suna shafar jikin ta hanyoyi daban-daban. Lantus insulin analogues sun hada da:

• Tujeo (glargine insulin). Ofasar Asalinta Jamus.
• Aylar (glargine insulin). Ofasar asalin India.
• Levemir (insulin detemir). Ofasar Asalinta Denmark.

Mafi mashahuri analog shine Tujeo. Babban bambanci tsakanin insulin lantus da tujeo shi ne cewa suna aiki daban ne akan wata halitta daban. A Rasha, masu cutar sukari masu kamuwa da cuta ta 1 suna canjawa zuwa Tujeo, amma ba kowa bane ke da tasirin da ake so kuma yana rage sukari.

Game da Levemira, wannan magani an rarrabe shi da kayan aikinsa. Kuma Aylar ya bambanta sosai a farashin, sabanin Lantus, amma a lokaci guda yana da umarni iri ɗaya da abun da ke ciki.

Kafin kowane allurar wannan miyagun ƙwayoyi, dole ne a hankali saka idanu akan sashi. Tunda yana samuwa ne kawai ta hanyar takardar sayan magani, shawara kafin amfani ana buƙatar gaggawa. Idan batun yawan abin sama da ya kamata, dole ne a dauki matakai don kawar da haɗari da haɗarin rikitarwa. Ba za ku iya yin jinkiri ba tare da jinƙai na hypoglycemia, tun da yake yana iya tayar da komputa.

Prohibitedaramar yara an haramta yin alluran wannan magani. Don sanin daidai duk cututtukan da ke haifar da cutar, yana da kyau a yi nazarin umarnin kafin a fara allura.

Insulin Lantus Solostar: sake dubawa da farashi, umarnin don amfani

Insulin Lantus SoloStar kwatankwacin kwatancen hormone ne tare da tsawan lokaci, wanda aka yi niyya don maganin nau'in 1 da nau'in ciwon sukari na 2. Abubuwan da ke aiki da miyagun ƙwayoyi shine insulin glargine, ana samun wannan kayan ne daga Escherichiacoli DNA ta amfani da hanyar ma'adanar.

Glargin yana da ikon ɗaure wa masu karɓar insulin kamar insulin ɗan adam, don haka miyagun ƙwayoyi suna da duk abubuwan da suka dace na ilimin halittu a cikin hormone.

Da zaran cikin kitse na subcutaneous, insulin glargine yana haɓaka samuwar microprecipitate, saboda wanda adadin adadin kwayoyin zai iya shigar da jinin jini koda yaushe. Wannan kayan yana samar da ingantaccen bayanin hangen nesa mai santsi.

Wanda ya kirkirar maganin shine kamfanin kasar Sanofi-Aventis Deutschland GmbH. Babban abu mai amfani da miyagun ƙwayoyi shine insulin glargine, abun da ke ciki ya haɗa da kayan taimako a cikin tsarin metacresol, chloride zinc, glycerol, sodium hydroxide, hydrochloric acid, ruwa don yin allura.

Lantus shine bayyananne, ruwa mara launi ko kusan ruwa mara launi. Mayar da mafita don warware ƙananan aikin shine 100 U / ml.

Kowane katun gilashin yana da maganin mil 3 na magani; an ɗora wannan katangar a cikin murfin sirinji na SoloStar. Ana sayar da alkalan insulin biyar don sirinji a cikin kwali, kwalin ya haɗa da jagorar koyarwa don na'urar.

• Za'a iya siye magungunan da ke da kyakkyawan nazari daga likitoci da marasa lafiya a kantin magani kawai tare da takardar sayen magani.
• An nuna insulin Lantus ga mellitus-insulin-da ke fama da ciwon sukari a cikin manya da yara sama da shekara shida.
• Tsarin musamman na SoloStar yana ba da damar jiyya a cikin yara sama da shekara biyu.
• Farashin kayan haɗi na alkalami guda biyar da magani na 100 IU / ml shine 3 500 rubles.

Kafin amfani da miyagun ƙwayoyi, ya kamata ka nemi likitanka, wani endocrinologist zai taimake ka ka zabi madaidaicin sashi kuma ya tsara ainihin lokacin allura. Insulin yana allurar subcutaneously sau ɗaya a rana, yayin da allurar take yin ta sosai a wani lokaci.

An shigar da miyagun ƙwayoyi a cikin ƙashin ƙarƙashin cinya na cinya, kafada ko ciki. Kowane lokaci ya kamata ku canza wurin allurar don kada haushi ya haifar da fata. Za'a iya amfani da maganin a matsayin magani mai zaman kanta, ko a hade tare da wasu magunguna masu rage sukari.

Kafin amfani da insulin Lantus SoloStar a cikin sirinji na alkalami don magani, kuna buƙatar gano yadda ake amfani da wannan na'urar don yin allura. Idan a baya ana yin aikin insulin tare da taimakon insulin aiki na dindindin ko na matsakaita, yawan kwalliyar yau da kullun na insulin basal yakamata a daidaita.

1. Game da canji daga allura sau biyu na insulin-isophan zuwa allura guda daya da Lantus ya yi a cikin makonni biyu na farko, yakamata a rage kashi na rana na yau da kullun da kashi 20-30. Ya kamata a biya kason da ya rage ta hanyar kara yawan amfani da insulin gajere.
2. Wannan zai hana ci gaban hauhawar jini a cikin dare da safe. Hakanan, lokacin sauya sheka zuwa sabon magani, ana kara samun amsa game da allura na kwayoyin lokacin. Sabili da haka, da farko, ya kamata a hankali kula da matakin sukari na jini ta amfani da glucometer kuma, idan ya cancanta, daidaita tsarin sashi na insulin.
3. Tare da ingantacciyar ƙa'idar aiki na metabolism, wani lokacin hankali ga miyagun ƙwayoyi na iya ƙaruwa, a wannan batun, ya zama dole don daidaita tsarin sashi. Hakanan ana buƙatar canza sashi ana buƙatar lokacin da ake canza salon rayuwar masu ciwon sukari, haɓaka ko rage nauyi, canza lokacin allura da sauran abubuwan da ke ba da gudummawa ga farawar hypo-ko hyperglycemia.
4. An haramta yin amfani da miyagun ƙwayoyi don gudanarwar cikin jijiya, wannan na iya haifar da haɓakar ƙuntataccen ƙwayar cuta. Kafin yin allura, yakamata ka tabbata cewa alkairin danshi mai tsabta ne kuma mai bakararre.

A matsayinka na doka, ana gudanar da insulin na Lantus a maraice, satin na farko na iya zama raka'a 8 ko fiye. Lokacin canzawa zuwa sabon magani, nan da nan gabatar da babban kashi yana da haɗari ga rayuwa, don haka yakamata a yi gyara a hankali.

Glargin fara aiki da sa'a guda bayan allura, a matsakaita, yana yin awowi 24. Koyaya, yana da mahimmanci a yi la’akari da cewa tare da babban sashi, tsawon lokacin da maganin zai iya kaiwa awa 29.

Kada insulin Lantus tare da wasu kwayoyi.

Tare da gabatarwar wani sashi mai yawa na insulin, mai ciwon sukari na iya fuskantar cutar sikari. Kwayar cuta ta rikicewar jiki yakan fara bayyana kwatsam kuma yana haɗuwa da jin gajiya, ƙaruwa mai rauni, rauni, raguwar damuwa, matsananciyar damuwa, tashin hankali na gani, ciwon kai, tashin zuciya, tashin hankali, da bushewa.

Wadannan bayyanannu yawanci alamu ne a cikin nau'ikan ji na yunwar, tashin zuciya, tashin hankali ko rawar jiki, damuwa, fatar jiki, bayyanar gumi mai sanyi, tachycardia, bugun zuciya. Mai tsananin rashin ƙarfi na hypoglycemia na iya haifar da lalacewar tsarin mai juyayi, don haka yana da mahimmanci a taimaka wa mai ciwon sukari cikin lokaci.

A cikin halayen da ba kasafai ba, mai haƙuri yana da rashin lafiyan jiyya ga ƙwayar, wanda ke haɗuwa da tasirin fata mai narkewa, angioedema, bronchospasm, hauhawar jijiya, girgiza, wanda kuma haɗari ne ga mutane.

Bayan allurar insulin, ƙwayoyin rigakafi zuwa abu mai aiki na iya ƙirƙirar. A wannan yanayin, ya zama dole don daidaita tsarin jigilar magunguna don kawar da haɗarin haɓakar hypo- ko hyperglycemia. Da wuya, a cikin masu ciwon sukari, dandano na iya canzawa, a lokuta da ƙarancin yanayi, ayyukan gani na wucin gadi ne sakamakon canji cikin abubuwan gani na tabarau na ido.

Yawancin lokaci, a cikin allurar, masu ciwon sukari suna haɓakar lipodystrophy, wanda ke rage jinkirin shan ƙwayoyi. Don kauce wa wannan, kuna buƙatar canza shafin allurar akai-akai. Hakanan, redness, itching, soreness na iya bayyana akan fatar, wannan yanayin na ɗan lokaci ne kuma yawanci yakan ɓace bayan kwanaki da yawa.

• Ba za a yi amfani da insulin Lantus tare da tashin hankali zuwa glargine mai aiki ko wasu abubuwan taimako na miyagun ƙwayoyi ba. An haramta amfani da miyagun ƙwayoyi don amfani a cikin yara 'yan shekaru shida, amma likita na iya ba da takaddama na musamman na SoloStar, waɗanda aka yi niyya ga yaran.
• Yakamata a yi taka tsantsan yayin aikin insulin yayin ciki da shayarwa. Yana da mahimmanci kowace rana don auna sukari na jini da sarrafa hanyar cutar. Bayan haihuwa, ya zama dole don daidaita sashi na maganin, tunda ana rage bukatar insulin a wannan lokacin.

Yawancin lokaci, likitoci sun ba da shawarar yayin daukar ciki tare da ciwon sukari don yin amfani da wani analog na insulin na dogon lokaci - maganin Levemir.

Game da yawan abin sama da ya kamata, an dakatar da matsakaiciyar jini ta hanyar daukar samfuran da suka hada da abubuwan carbohydrates cikin sauri. Bugu da ƙari, tsarin kulawa yana canzawa, an zaɓi abinci mai dacewa da aikin jiki.

A cikin hypoglycemia mai tsanani, ana gudanar da glucagon a cikin intramuscularly ko subcutaneously, kuma ana ba da allurar rigakafin ƙwayar glucose mai rauni.

Ciki har da likita na iya yin amfani da maganin carbohydrates.

Kafin yin allura, kuna buƙatar bincika yanayin kabad ɗin da aka sanya a cikin alkairin sirinji. Maganin zai zama m, mara launi, ba dauke da laka ko abubuwan gani na waje, na ruwa mai daidaituwa.

Alkalami na syringe naura ne wanda za'a iya dashi, saboda haka, bayan allura, dole ne a zubar dashi, sake amfani da shi na iya haifar da kamuwa da cuta. Kowane allura ya kamata a yi tare da sabon allurar bakararre, don wannan dalili ana amfani da allura na musamman, waɗanda aka kera su don sirinji alkalami daga wannan ƙirar.

Dole ne a zubar da na'urorin da suka lalace, tare da ɗanɗanar shakkuwar cutarwar, ba za a yi allura tare da wannan alkalami ba. A wannan batun, masu ciwon sukari dole ne a koyaushe su sami ƙarin sirinji don maye gurbin su.

1. An cire maɓallin kariya daga na'urar, bayan wannan alamar akan ɗakin insulin tabbas tabbas ana duba shi don tabbatar da cewa kyakkyawan shiri ya kasance. Ana kuma nazarin bayyanar mafita, a gaban laka, ƙwayar baƙin waje ko daidaituwar turbid, ya kamata a maye gurbin insulin tare da wani.
2. Bayan an cire murfin kariya, allurar mai tazara a hankali kuma a haɗe take da alkalami na syringe. Kowane lokaci kuna buƙatar bincika na'urar kafin yin allura. Yana da mahimmanci a tabbatar da cewa dabino ya kasance da farko a 8, wanda ke nuna cewa ba'a yi amfani da sirinji ba kafin.
3. Don saita adadin da ake so, maɓallin farawa an cire shi gabaɗaya, bayan wannan mai zaɓin kashi ba zai iya juyawa ba. Yakamata a cire murfin waje da na ciki, a kiyaye su har sai an gama aikin, domin bayan allurar, cire allurar da aka yi amfani da ita.
4. Ana riƙe alkalami na syringe ta allura, bayan haka kuna buƙatar sauƙaƙe yatsunku a kan tafkin insulin don iska a cikin kumfa ta iya tashi zuwa allura. Bayan haka, ana danna maɓallin farawa koyaushe. Idan na'urar ta shirya don amfani, ƙaramin digo ya kamata ya bayyana a ƙarshen allura. Idan babu digo, ana sake maimaita siren syringe.

Mai ciwon sukari na iya zaɓar sashin da ake so daga raka'a 2 zuwa 40, mataki ɗaya a wannan yanayin shine raka'a 2. Idan ya zama dole don gudanar da karuwar insulin, ana yin allura biyu.

A kan ma'aunin insulin na saura, zaku iya bincika yawan ƙwayar da aka bari a na'urar. Lokacin da piston na baƙin fata ya kasance a cikin farkon ɓangaren tsiri mai launin, adadin maganin shine 40 PIECES, idan an sanya piston a ƙarshen, kashi shine 20 PIECES. Ana za selectar mai za dosear kashi har sai maɓallin kibiya ya isa kashi da ake so.

Don cika alkalami insulin, an ja maɓallin fara allurar zuwa iyaka. Kuna buƙatar tabbatar da cewa an zaɓi miyagun ƙwayoyi a cikin sashi ɗin da ake buƙata. An canza maɓallin farawa zuwa gwargwadon adadin hormone da ya rage a cikin tanki.

Yin amfani da maɓallin farawa, masu ciwon sukari na iya bincika nawa aka tattara insulin. A lokacin tabbatarwa, ana kiyaye mabuɗin. Yawan adadin miyagun ƙwayoyi da aka ɗauka za'a iya yin hukunci da shi ta layin ƙarshe da aka gani.

• Dole ne mara lafiyar ya koyi yin amfani da allon insulin kafin lokacin, ƙwararrun aikin insulin dole ne su sami horo daga ma'aikatan kiwon lafiya a asibitin. Ana saka allurar koyaushe a ƙarƙashin subcutane, bayan haka ana danna maɓallin farawa zuwa iyaka. Idan an matsa maɓallin gabaɗaya, danna mai sauraro zai yi sauti.
• Ana riƙe maɓallin farawa har na 10 seconds, bayan haka za'a iya cire allura. Wannan dabarar allurar tana ba ka damar shigar daukacin maganin. Bayan an yi allura, sai a cire allura daga alkairin da aka zubar kuma ba za ku sake amfani da ita ba. Ana sanya hula mai kariya a allon alkairin.
• Kowane alkalami na insulin yana tare da littafin koyarwa, inda zaku iya gano yadda ake amfani da katako yadda yakamata, haɗa allura da allura. Kafin gudanar da insulin, dole kirinjin aƙalla ya zama aƙalla sa'o'i biyu a zafin jiki. Kar a sake amfani da katako na fanko.

Yana yiwuwa a adana insulin Lantus a ƙarƙashin yanayin zafin jiki daga digiri 2 zuwa 8 a cikin duhu, nesa da hasken rana kai tsaye. Ya kamata a sanya magungunan ta hanyar isar da yara.

Rayuwar sel ta insulin shekaru uku ne, wanda bayan haka ya kamata a watsar da mafita, ba za a iya amfani da shi don nufin sa ba.

Magunguna iri ɗaya tare da tasirin hypoglycemic sun haɗa da insulin Levemir, wanda ke da kwalliya sosai. Wannan magani kwatankwacin kwalliya ce ta insulin aiki na mutum.

Ana samar da kwayar ta hanyar amfani da kwayar halitta ta halittar DNA ta hanyar amfani da wani irin nau'in Saccharomyces cerevisiae. Levemir an shigar dashi cikin jikin mai ciwon sukari ne kawai a kasa. An ba da umarnin sashi da kuma yawan allura ta likita mai halarta, gwargwadon halayen mutum na masu haƙuri.

Lantus zaiyi magana game da insulin daki-daki a cikin bidiyo a wannan labarin.

Insulin Lantus: koyarwa, kwatanta da analogues, farashi

Yawancin shirye-shiryen insulin a Rasha sun samo asali ne. Daga cikin tsoffin analogues na insulin, Lantus, wanda ɗayan manyan kamfanonin magunguna Sanofi kera shi, ana yin amfani dashi sosai.

Duk da gaskiyar cewa wannan maganin yana da tsada sosai fiye da NPH-insulin, rabon kasuwar sa yana ci gaba. An bayyana wannan ta hanyar sakamako mai tsayi da santsi mai sauƙi. Zai yuwu ku ɗanɗana Lantus sau ɗaya a rana. Magungunan sun ba ka damar sarrafa nau'ikan cututtukan mellitus guda biyu, ka guji hauhawar jini, kuma yana ba da amsawar rashin lafiyan sau da yawa.

An fara amfani da insulin Lantus a cikin 2000, an yi rajista a Rasha bayan shekaru 3. A cikin lokutan da suka gabata, miyagun ƙwayoyi sun tabbatar da amincinsa da ingancinsa, an sanya shi cikin jerin Magungunan Mahimmanci da mahimmanci, don haka masu ciwon sukari na iya samun shi kyauta.

Abubuwan da ke aiki shine glargine insulin. Idan aka kwatanta da kwayar halittar mutum, ana ƙara inganta ƙwayar glargine: ana maye gurbin acid ɗaya, an ƙara biyu. Bayan gudanarwa, irin wannan insulin a sauƙaƙe yana samar da hadaddun ƙwayoyi a ƙarƙashin fata - hexamers. Maganin yana da pH na acidic (kimanin 4), wanda ya sa adadin kuzarin hexamers yayi ƙasa da hasara.

Baya ga glargine, Lantus insulin ya ƙunshi ruwa, abubuwan antiseptik m-cresol da zinc chloride, da glycerol stabilizer. Ana samun acidity ɗin da ake buƙata na maganin an samu ta hanyar ƙara sodium hydroxide ko acid hydrochloric.

Duk da peculiarities na kwayar halittar, glargine yana da ikon ɗaure wa masu karɓar sel daidai da insulin ɗan adam, don haka ka'idodin aiki yayi kama da su. Lantus yana ba ku damar tsara metabolism na glucose idan akwai karancin insulin kansa: yana ƙarfafa tsokoki da tsotsin nama na adipose don ɗaukar sukari, kuma yana hana aikin glucose ta hanta.

Tun da Lantus wani kwazo ne mai aiki da jiki, ana allurar dashi don kiyaye glucose mai azumi. A matsayinka na mai mulki, idan akwai ciwon sukari mellitus, tare da Lantus, an tsara gajeren insulins - Insuman na masana'antun guda ɗaya, analogues ko ultravort Novorapid da Humalog.

Ana yin lissafin kashi na insulin a kan tsarin karatun azumi na glucoeter din tsawon kwanaki. An yi imani da cewa Lantus yana samun cikakken ƙarfi a cikin kwanaki 3, don haka daidaitawar kashi na iya yiwuwa ne kawai bayan wannan lokacin. Idan matsakaita na yau da kullun na azumin glycemia shine> 5.6, sashi na Lantus yana ƙaruwa da raka'a 2.

Ana la'akari da kashi daidai daidai idan babu hypoglycemia, da kuma haemoglobin (HG) bayan watanni 3 na amfani da zafin jiki a 30 ° C).

A kan sayarwa zaka iya samun zaɓuɓɓuka 2 don insulin Lantus. Na farko an yi shi ne a cikin Jamus, cike yake a Rasha. Karo na biyu na cikakken samarwa ya faru ne a Rasha a kamfanin Sanofi dake yankin Oryol. Dangane da marasa lafiya, ingancin magungunan daidai suke, sauyawa daga zaɓi ɗaya zuwa wani ba ya haifar da matsala.

Insulin Lantus dogon magani ne. Yana da kusan babu kololuwa kuma yana aiki a matsakaici a cikin sa'o'i 24, aƙalla 29 hours. Tsawon lokaci, ƙarfin aiki, buƙatar insulin ya dogara da halaye na mutum da nau'in cutar, saboda haka, an zaɓi tsarin kulawa da sashi don kowane mai haƙuri daban-daban.

Umarnin don amfani da shawarar bada allurar Lantus sau ɗaya a rana, a lokaci guda. A cewar masu ciwon sukari, tsarin sau biyu ya fi tasiri, saboda yana ba da damar yin amfani da magunguna daban-daban na dare da rana.

Yawan Lantus da ake buƙata don daidaita al'ada glycemia na azumi ya dogara da kasancewar insulin na ciki, jurewar insulin, daɗaɗɗen ƙwaƙwalwar jijiyoyin daga ƙwayar subcutaneous, da kuma matakin ayyukan masu ciwon sukari. Ba za a yi amfani da tsarin koyon maganin ta duniya ba. A matsakaici, jimlar buƙatar insulin daga 0.3 zuwa 1 raka'a. kowace kilogram, rabon Lantus a wannan yanayin ya kai 30-50%.

Hanya mafi sauki ita ce yin lissafin adadin Lantus ta hanyar nauyi, ta amfani da tsari na yau da kullun: 0.2 x nauyi a cikin kilogiram = kashi ɗaya na Lantus tare da allura guda. Irin wannan ƙidaya ba daidai ba kuma kusan koyaushe na bukatar gyara.

Lissafin insulin a cewar glycemia yana ba, a matsayin mai mulkin, mafi kyawun sakamako. Da farko, ƙayyade adadin don allurar maraice, saboda ya ba da asalin yanayin insulin a cikin jini a cikin dukan dare. Yiwuwar cutar hypoglycemia a cikin marasa lafiya akan Lantus yana da ƙasa da akan NPH-insulin. Koyaya, saboda dalilai na aminci, suna buƙatar saka idanu na sukari na lokaci-lokaci a cikin mafi haɗari - a farkon safiya, lokacin da aka kunna samar da kwayoyin-antagonists na insulin.

Da safe, ana gudanar da Lantus don kiyaye sukari a cikin komai a ciki kullun. Matsakaicinsa baya dogaro da adadin carbohydrates a cikin abincin. Kafin karin kumallo, kuna buƙatar kwantar da Lantus da gajeren insulin. Haka kuma, bashi yiwuwa a kara allurai kuma a gabatar da nau'in insulin guda daya ne kawai, tunda yanayin aikinsu ya sha bamban. Idan kana buƙatar allurar dogon bacci kafin lokacin bacci, kuma glucose yana ƙaruwa, yi allura 2 a lokaci guda: Lantus a cikin kashi na yau da kullun da gajeren insulin. Ana iya yin lissafin daidaitaccen sashi na gajeren hormone ta hanyar amfani da forsham, ƙididdigar ɗaya dangane da gaskiyar cewa 1 rukunin insulin zai rage sukari da kusan 2 mmol / L.

Idan an yanke shawarar yin allurar Lantus SoloStar bisa ga umarnin, wato, sau ɗaya a rana, zai fi kyau a yi wannan kusan awa ɗaya kafin a kwanta barci. A wannan lokacin, kashi na farko na insulin suna da lokaci don shiga jini. An zaɓi kashi a cikin irin wannan hanyar don tabbatar da glycemia na al'ada da dare da safe.

Lokacin da aka gudanar da shi sau biyu, allurar farko ana yin ta ne bayan farkawa, na biyu - kafin lokacin bacci. Idan sukari yayi daidai da daddare kuma a ɗanɗaɗa shi da safe, zaku iya gwada motsi abincin dare zuwa farkon lokacin, kusan awanni 4 kafin kwanciya.

Yawaitar cututtukan type 2, da wahalar bin karancin abinci mai kazami, da yawaitar amfani da magunguna masu rage sukari sun haifar da fitowar sabbin hanyoyin magani.

Yanzu akwai shawarwari don fara allurar insulin idan haemoglobin glycated ya fi 9%. Yawancin karatu sun nuna cewa farkon farawar insulin da kuma saurin canzawa zuwa tsari mai zurfi yana ba da sakamako mafi kyau fiye da magani "zuwa tsayawa" tare da wakilai na hypoglycemic. Wannan hanyar na iya rage haɗarin rikice-rikice na ciwon sukari na 2: yawan rage raguwar kashi 40%, ido da ƙananan ƙwayar microgoniopathy an rage da 37%, yawan mutuwar ya rage da 21%.

Tabbatar da ingantaccen tsarin magani:

1. Bayan ganewar asali - abinci, wasanni, Metformin.
2. Lokacin da wannan ilimin bai isa ba, ana ƙara shirye-shiryen sulfonylurea.
3. Tare da ci gaba na gaba, canji na rayuwa, metformin da dogon insulin.
4. Sannan a ƙara yin insulin gajere zuwa insulin mai tsawo, ana amfani da tsari mai zurfi na ilimin insulin.

A cikin matakan 3 da 4, ana iya amfani da Lantus cikin nasara. Sakamakon dogon aikin tare da nau'in ciwon sukari na 2, allura guda ɗaya a rana ya isa, rashi kololuwa yana taimakawa ci gaba da insulin basal a matakin guda koyaushe. An gano cewa bayan canzawa zuwa Lantus a cikin yawancin masu ciwon sukari tare da GH> 10% bayan watanni 3, matakinsa yana raguwa da 2%, bayan rabin shekara ya isa ga al'ada.

Dogon aiki guda 2 ne kawai masana'antun guda 2 ne suka kirkira - Novo Nordisk (magungunan Levemir da Tresiba) da Sanofi (Lantus da Tujeo).

Kwatanta halaye na kwayoyi a cikin alkalami alkalami:

1. 
   Filatova, M.V. Darasi na nishaɗi don ciwon sukari mellitus / M.V. Filatova. - M.: AST, Sova, 2008 .-- 443 p.
2. 
   Tkachuk V. A. Gabatarwa ga endocrinology na kwayoyin: monograph. , Gidan Jarida na MSU - M., 2015. - 256 p.
3. 
   Cututtukan Endocrine da ciki a cikin tambayoyi da amsoshi. Jagorar likitoci, E-noto - M., 2015. - 272 c.

Bari in gabatar da kaina. Sunana Elena. Na kasance ina aiki a matsayin endocrinologist fiye da shekaru 10. Na yi imanin cewa a halin yanzu ni ƙwararre ne a fagen aikina kuma ina so in taimaka wa duk baƙi zuwa shafin don warware matsalolin da ba ayyuka sosai ba. Duk kayan don rukunin yanar gizon an tattara su kuma ana aiwatar dasu da kyau don isar da sanarwa gwargwadon iko. Kafin amfani da abin da aka bayyana akan gidan yanar gizon, tattaunawa mai mahimmanci tare da kwararru koyaushe wajibi ne.

Littafin koyarwa

An fara amfani da insulin Lantus a cikin 2000, an yi rajista a Rasha bayan shekaru 3. A cikin lokutan da suka gabata, miyagun ƙwayoyi sun tabbatar da amincinsa da ingancinsa, an sanya shi cikin jerin Magungunan Mahimmanci da mahimmanci, don haka masu ciwon sukari na iya samun shi kyauta.

Abubuwan da ke aiki shine glargine insulin. Idan aka kwatanta da kwayar halittar mutum, ana ƙara inganta ƙwayar glargine: ana maye gurbin acid ɗaya, an ƙara biyu. Bayan gudanarwa, irin wannan insulin a sauƙaƙe yana samar da hadaddun ƙwayoyi a ƙarƙashin fata - hexamers. Maganin yana da pH na acidic (kimanin 4), wanda ya sa adadin kuzarin hexamers yayi ƙasa da hasara.

Baya ga glargine, Lantus insulin ya ƙunshi ruwa, abubuwan antiseptik m-cresol da zinc chloride, da glycerol stabilizer. Ana samun acidity ɗin da ake buƙata na maganin an samu ta hanyar ƙara sodium hydroxide ko acid hydrochloric.

Duk da peculiarities na kwayar halittar, glargine yana da ikon ɗaure wa masu karɓar sel daidai da insulin ɗan adam, don haka ka'idodin aiki yayi kama da su. Lantus yana ba ku damar tsara metabolism na glucose idan akwai karancin insulin kansa: yana ƙarfafa tsokoki da tsotsin nama na adipose don ɗaukar sukari, kuma yana hana aikin glucose ta hanta.

Tun da Lantus wani kwazo ne mai aiki da jiki, ana allurar dashi don kiyaye glucose mai azumi. A matsayinka na mai mulki, idan akwai ciwon sukari mellitus, tare da Lantus, an tsara gajeren insulins - Insuman na masana'antun guda ɗaya, analogues ko ultravort Novorapid da Humalog.

Ana yin lissafin kashi na insulin a kan tsarin karatun azumi na glucoeter din tsawon kwanaki. An yi imani da cewa Lantus yana samun cikakken ƙarfi a cikin kwanaki 3, don haka daidaitawar kashi na iya yiwuwa ne kawai bayan wannan lokacin. Idan matsakaita na yau da kullun na azumin glycemia shine> 5.6, sashi na Lantus yana ƙaruwa da raka'a 2.

Ana la'akari da kashi daidai daidai idan babu hypoglycemia, da kuma haemoglobin (HG) bayan watanni 3 na amfani da zafin jiki a 30 ° C).

A kan sayarwa zaka iya samun zaɓuɓɓuka 2 don insulin Lantus. Na farko an yi shi ne a cikin Jamus, cike yake a Rasha. Karo na biyu na cikakken samarwa ya faru ne a Rasha a kamfanin Sanofi dake yankin Oryol. Dangane da marasa lafiya, ingancin magungunan daidai suke, sauyawa daga zaɓi ɗaya zuwa wani ba ya haifar da matsala.

Bayani Aikace-aikacen Lantus

Insulin Lantus dogon magani ne. Yana da kusan babu kololuwa kuma yana aiki a matsakaici a cikin sa'o'i 24, aƙalla 29 hours. Tsawon lokaci, ƙarfin aiki, buƙatar insulin ya dogara da halaye na mutum da nau'in cutar, saboda haka, an zaɓi tsarin kulawa da sashi don kowane mai haƙuri daban-daban.

Umarnin don amfani da shawarar bada allurar Lantus sau ɗaya a rana, a lokaci guda. A cewar masu ciwon sukari, tsarin sau biyu ya fi tasiri, saboda yana ba da damar yin amfani da magunguna daban-daban na dare da rana.

Yin lissafi

Yawan Lantus da ake buƙata don daidaita al'ada glycemia na azumi ya dogara da kasancewar insulin na ciki, jurewar insulin, daɗaɗɗen ƙwaƙwalwar jijiyoyin daga ƙwayar subcutaneous, da kuma matakin ayyukan masu ciwon sukari. Ba za a yi amfani da tsarin koyon maganin ta duniya ba. A matsakaici, jimlar buƙatar insulin daga 0.3 zuwa 1 raka'a. kowace kilogram, rabon Lantus a wannan yanayin ya kai 30-50%.

Hanya mafi sauki ita ce yin lissafin adadin Lantus ta hanyar nauyi, ta amfani da tsari na yau da kullun: 0.2 x nauyi a cikin kilogiram = kashi ɗaya na Lantus tare da allura guda. Wannan lissafin ba daidai bane kuma kusan koyaushe na bukatar gyara.

Lissafin insulin a cewar glycemia yana ba, a matsayin mai mulkin, mafi kyawun sakamako. Da farko, ƙayyade adadin don allurar maraice, saboda ya ba da asalin yanayin insulin a cikin jini a cikin dukan dare. Yiwuwar cutar hypoglycemia a cikin marasa lafiya akan Lantus yana da ƙasa da akan NPH-insulin. Koyaya, saboda dalilai na aminci, suna buƙatar saka idanu na sukari na lokaci-lokaci a cikin mafi haɗari - a farkon safiya, lokacin da aka kunna samar da kwayoyin-antagonists na insulin.

Da safe, ana gudanar da Lantus don kiyaye sukari a cikin komai a ciki kullun. Matsakaicinsa baya dogaro da adadin carbohydrates a cikin abincin. Kafin karin kumallo, kuna buƙatar kwantar da Lantus da gajeren insulin. Haka kuma, bashi yiwuwa a kara allurai kuma a gabatar da nau'in insulin guda daya ne kawai, tunda yanayin aikinsu ya sha bamban. Idan kana buƙatar allurar dogon bacci kafin lokacin bacci, kuma glucose yana ƙaruwa, yi allura 2 a lokaci guda: Lantus a cikin kashi na yau da kullun da gajeren insulin. Ana iya yin lissafin daidaitaccen sashi na gajeren hormone ta hanyar amfani da forsham, ƙididdigar ɗaya dangane da gaskiyar cewa 1 rukunin insulin zai rage sukari da kusan 2 mmol / L.

Lokacin Gabatarwa

Idan an yanke shawarar yin allurar Lantus SoloStar bisa ga umarnin, wato, sau ɗaya a rana, zai fi kyau a yi wannan kusan awa ɗaya kafin a kwanta barci. A wannan lokacin, kashi na farko na insulin suna da lokaci don shiga jini. An zaɓi kashi a cikin irin wannan hanyar don tabbatar da glycemia na al'ada da dare da safe.

Lokacin da aka gudanar da shi sau biyu, allurar farko ana yin ta ne bayan farkawa, na biyu - kafin lokacin bacci. Idan sukari yayi daidai da daddare kuma a ɗanɗaɗa shi da safe, zaku iya gwada motsi abincin dare zuwa farkon lokacin, kusan awanni 4 kafin kwanciya.

Haɗuwa tare da allunan hypoglycemic

Yawaitar cututtukan type 2, da wahalar bin karancin abinci mai kazami, da yawaitar amfani da magunguna masu rage sukari sun haifar da fitowar sabbin hanyoyin magani.

Yanzu akwai shawarwari don fara allurar insulin idan haemoglobin glycated ya fi 9%. Yawancin karatu sun nuna cewa farkon farawar insulin da kuma saurin canzawa zuwa tsari mai zurfi yana ba da sakamako mafi kyau fiye da magani "zuwa tsayawa" tare da wakilai na hypoglycemic. Wannan hanyar na iya rage haɗarin rikice-rikice na ciwon sukari na 2: yawan rage raguwar kashi 40%, ido da ƙananan ƙwayar microgoniopathy an rage da 37%, yawan mutuwar ya rage da 21%.

Tabbatar da ingantaccen tsarin magani:

1. Bayan ganewar asali - abinci, wasanni, Metformin.
2. Lokacin da wannan ilimin bai isa ba, ana ƙara shirye-shiryen sulfonylurea.
3. Tare da ci gaba na gaba, canji na rayuwa, metformin da dogon insulin.
4. Sannan a ƙara yin insulin gajere zuwa insulin mai tsawo, ana amfani da tsari mai zurfi na ilimin insulin.

A cikin matakan 3 da 4, ana iya amfani da Lantus cikin nasara. Sakamakon dogon aikin tare da nau'in ciwon sukari na 2, allura guda ɗaya a rana ya isa, rashi kololuwa yana taimakawa ci gaba da insulin basal a matakin guda koyaushe. An gano cewa bayan canzawa zuwa Lantus a cikin yawancin masu ciwon sukari tare da GH> 10% bayan watanni 3, matakinsa yana raguwa da 2%, bayan rabin shekara ya isa ga al'ada.

Dogon aiki guda 2 ne kawai masana'antun guda 2 ne suka kirkira - Novo Nordisk (magungunan Levemir da Tresiba) da Sanofi (Lantus da Tujeo).

Kwatanta halaye na kwayoyi a cikin alkalami alkalami:

Lantus ko Levemir - Wanne ya fi kyau?

Ingantaccen insulin tare da kusan koda bayanan aikin ana iya kiran su Lantus da Levemir (ƙari game da Levemir). Lokacin amfani da ɗayan ɗayansu, kuna iya tabbata cewa yau zai yi aiki daidai da na jiya. Tare da madaidaicin kashi na tsawon insulin, zaku iya yin bacci cikin kwanciyar hankali duk dare ba tare da tsoron cutar sikila ba.

Bambancin magunguna:

Likita na Kimiyyar Kimiyya, Shugaban Cibiyar Nazarin Diabetology - Tatyana Yakovleva

Na yi shekaru da yawa ina nazarin ciwon sukari. Yana da ban tsoro yayin da mutane da yawa suka mutu, har ma da yawa suna zama masu rauni saboda cutar sankara.

Na yi hanzarin ba da labari mai daɗi - Cibiyar Binciken Endocrinological na Kwalejin Kimiyya ta Rasha ta sami nasarar inganta maganin da ke warkar da ciwon sukari gaba ɗaya. A yanzu, ingancin wannan magani yana gab da kashi 98%.

Wani albishir: Ma'aikatar Lafiya ta tabbatar da ɗaukar wani shiri na musamman wanda zai biya diyyar magunguna mai yawa. A Rasha, masu ciwon sukari har sai 18 ga Mayu (m) samun shi - Don kawai 147 rubles!

1. Aikin Levemir ya yi laushi. A kan zane, wannan bambancin a bayyane yake a bayyane, a rayuwa ta ainihi kusan ba zata iya yiwuwa ba. Dangane da sake dubawa, sakamakon abubuwan insulins iri daya ne, lokacin da aka sauya sheka daga wani zuwa juna, yawanci ba lallai ne ku canza sashi ba.
2. Lantus yana aiki fiye da Levemir. A cikin umarnin don amfani, an bada shawarar saka shi sau 1, Levemir - har sau 2. A aikace, magungunan biyu suna aiki sosai idan an gudanar dasu sau biyu.
3. Levemir an fi son masu ciwon sukari tare da ƙarancin insulin. Ana iya siyan shi a cikin katako kuma saka shi a cikin alkairin sirinji tare da matakan dosing of 0.5 raka'a. Ana sayar da Lantus ne kawai a cikin alkalam ɗin da aka gama cikin ƙari na 1 naúrar.
4. Levemir yana da pH na tsaka tsaki, don haka ana iya dillancinsa, wanda yake da mahimmanci ga yara ƙanana da masu ciwon sukari da ke da hazaka mai ƙarfi ga hormone. Insulin Lantus yana asarar kaddarorinsa lokacin da aka lalata shi.
5. Levemir a cikin bude form an adana shi sau 1.5 ya fi tsayi (makonni 6 da 4 a Lantus).
6. Maƙerin ya yi iƙirarin cewa tare da nau'in ciwon sukari na 2, Levemir yana haifar da ƙarancin nauyi. A aikace, bambanci tare da Lantus sakaci ne.

Gaba ɗaya, magungunan biyu suna da alaƙa iri ɗaya, don haka tare da ciwon sukari babu wani dalili don canza ɗaya don ɗayan ba tare da isasshen dalili ba: ƙwayar cuta ko kulawar glycemic mara kyau.

Lantus ko Tujeo - me za a zaɓa?

Tujeo insulin shine ya samar da wannan kamfani kamar Lantus. Bambanci kawai tsakanin Tujeo shine haɓaka yawan insulin sau 3 a cikin bayani (U300 maimakon U100). Ragowar abun hade ne iri daya.

Bambanci tsakanin Lantus da Tujeo:

• Tujeo yana aiki har zuwa awanni 36, don haka bayanin ayyukansa ya zama mara nauyi, kuma hadarin cutar sanyin jini a ƙasa bai ragu ba
• a Mililiters, kashi na Tujeo kusan kashi uku bisa uku ne na insulin na Lantus,
• a raka'a - Tujeo yana buƙatar kusan 20% mafi
• Tujeo wani sabon magani ne, don haka ba a bincika tasirinsa ga jikin yaran ba. Umarni ya hana amfani da shi a cikin masu ciwon sukari a karkashin shekara 18,
• Dangane da sake dubawa, Tujeo ya fi dacewa da yin kuka a cikin allura, don haka dole ne a sauya shi kowane lokaci tare da sabon.

Komawa daga Lantus zuwa Tujeo abu ne mai sauqi: muna yin allurar da yawa kamar yadda muke a baya, kuma muna lura da cutar glycemia tsawon kwanaki 3. Wataƙila, ya kamata a daidaita sauƙin zuwa sama.

Lantus ko Tresiba - Wanne ya fi kyau?

Tresiba shine kawai mamba a cikin sabuwar kungiyar insulin na dogon-ins. Yana aiki har zuwa awanni 42. A halin yanzu, an samo shaidu cewa tare da nau'in cuta ta 2, maganin TGX yana rage GH ta 0.5%, hypoglycemia da 20%, sukari ya ragu da kusan 30% da dare.

Tare da nau'in ciwon sukari na 1, sakamakon ba shi da ƙarfafawa: GH yana raguwa da 0.2%, hypoglycemia na dare yana ƙasa da 15%, amma da rana, sukari yakan faɗi sau da yawa by 10%. Ganin cewa farashin Treshiba yana da girma sosai, har zuwa yanzu ana iya bada shawarar shi ga masu ciwon sukari masu fama da cutar 2 amma da haɓakar ciwon sukari. Idan ana iya rama cutar sankara da insulin Lantus, canzawar ba shi da ma'ana.

Lantus Reviews

Lantus shine insulin da aka fi so a Rasha. Fiye da 90% na masu ciwon sukari suna farin ciki da shi kuma suna iya ba da shi ga wasu. Abubuwan da ba a tabbatar da su ba marasa lafiya sun haɗa da doguwa, santsi, kwanciyar hankali da sakamako mai faɗi, sassauƙa na zaɓin kashi, sauƙi na amfani, allurar mara ciwo.

Amsa mai kyau ta cancanci ikon Lantus don cire hawan asuba a cikin sukari, rashin tasiri akan nauyi. Yawancinsa ba shi da ƙasa da NPH-insulin.

Daga cikin gazawar, marasa lafiya masu ciwon sukari suna lura da rashin katuwar katako ba tare da sirinji alkalami akan siyarwa ba, matsanancin matakin sashi, da warin insulin mara dadi.

Tabbatar koya! Shin kuna tsammanin kulawa da kwayoyin hana daukar ciki da insulin shine hanya daya tilo da za'a iya sarrafa sukari a karkashinta? Ba gaskiya bane! Kuna iya tabbatar da wannan da kanku ta hanyar fara amfani da shi. kara karantawa >>