Glucophage® (Glucophage®)

Ana samun magungunan a cikin allunan da aka saka a fim wanda aka hada da 500, 850 da 1000 MG. Allunan glucophage a allurai na 500 da 850 MG suna da zagaye, siffar biconvex da farin launi, wani taro mai hade da juna yana bayyane a sashin giciye, kuma wani nau'i mai kwalliya, fasalin biconvex da hadari a garesu a sashi na 1000 MG, farin taro iri daya a sashin giciye.

Abubuwan da ke aiki da miyagun ƙwayoyi shine metformin hydrochloride, abubuwa masu taimako - povidone da magnesium stearate. Filin fim na allunan Glucofage na 500 da 850 MG ya hada da hypromellose, 1000 MG na Opadry tsarkakakke (macrogol 400 + hypromellose).

Yawan kwamfutocin da ke cikin boka da blister a cikin kwali kwali ya dogara da sashi na miyagun ƙwayoyi:

• Allunan glucofage 500 MG - a cikin blisters na tsare tsare na aluminium ko PVC, guda 10 ko 20, a cikin wata kwali na kwarjin 3 ko 5 da kuma 15 a aljihun, a cikin wani kwali na kwali na 2 ko 4 murhun sel,
• Allunan glucofage 850 MG - a cikin blisters na tsare tsare na aluminium ko PVC, guda 15 kowannensu, a cikin kwali na fakitin 2 ko 4 blisters da kuma guda 20 a cikin buhunshi mai laushi, a cikin kwali na kwali na 3 ko 5 na blisters.
• Glucophage allunan 1000 MG - a cikin blisters na tsare tsare na aluminium ko PVC, guda 10 kowannensu, a cikin wani kwali na kwali na 3, 5, 6 ko 12 kwanogin blisters da 15 guda a cikin kumburi, a cikin wani kwali na 2, 3 ko 4 fitsari.

Alamu don amfani

Dangane da umarnin, ana amfani da Glucophage don nau'in ciwon sukari na II, musamman a cikin mutane masu kiba, tare da rashin isasshen aiki na jiki da kuma maganin abinci.

A cikin tsofaffi marasa lafiya, ana amfani da miyagun ƙwayoyi duka a hade tare da insulin ko wasu magunguna na hypoglycemic na baki, kuma azaman monotherapy.

A cikin yara da suka girmi shekaru 10, ana amfani da Glucofage a cikin haɗin gwiwa tare da insulin ko kuma a matsayin wakili kawai na warkewa.

Contraindications

Ba a sanya magani ba ga cututtukan da ke biyo baya da kuma halaye:

• Rashin gazawar da / ko rashi aiki na renal,
• Rashin hanta da / ko aiki na hanta,
• Cutar masu ciwon sukari da kuma precomatosis
• Ketoacidosis
• A bayyane bayyanar cututtuka alamun m da na kullum cututtuka da taimako zuwa ga ci gaba da nama hypoxia (m rashin ƙarfi infarction, zuciya da kuma na numfashi kasa, da dai sauransu),
• Raunin raunin da ya faru da tiyata wanda aka nuna maganin insulin,
• Cutar cututtuka mai saurin kamuwa, rashin ruwa, amai,
• Lactic acidosis
• Rashin shan giya na yau da kullun da guba na ethanol,
• Hypersensitivity ga abubuwan da ke cikin miyagun ƙwayoyi,
• Ciki
• Yarda da abinci mai kalori.

Yin amfani da Glucophage a cikin mata yayin shayarwa, marasa lafiya da suka wuce shekaru 60 da mutanen da suke yin aiki na zahiri (wannan yana da alaƙa da haɓakar haɓakar lactic acidosis) yana buƙatar taka tsantsan.

Sashi da gudanarwa

Magungunan an yi shi ne don gudanar da maganin baka (baka).

Lokacin da aka wajabta wa manya a matsayin wakili na monotherapeutic kuma a hade tare da sauran magungunan hypoglycemic, kashi na Glucofage, bisa ga umarnin, shine 500 ko 850 mg daga 2 zuwa 3 sau a rana yayin abinci ko bayan abinci. Dangane da abubuwan da ke cikin glucose a cikin jini, karuwa a yawan kashi yana yiwuwa a gaba.

Adadin kulawa, a matsayin mai mulkin, yana daga 1500 zuwa 2000 MG kowace rana. Rage haɗarin sakamako masu illa daga cututtukan gastrointestinal mai yiwuwa ne ta hanyar rarraba kashi na yau da kullun ta hanyar kashi 2-3. Matsakaicin izini na Glucofage kowace rana shine 3000 MG.

Graduarawar ƙwayar cuta a hankali yana inganta haƙuri da kwayoyi ta hanji.

Lokacin amfani da Glucofage a hade tare da insulin, kashi na farko na miyagun ƙwayoyi shine 500 ko 850 mg sau 2-3 a rana, kuma an zaɓi kashi na insulin daban-daban, dangane da tattarawar glucose a cikin jini.

An wajabta wa yara da yara kanana shekaru 10 haihuwa 500 ko 850 MG na magani sau ɗaya a rana tare da bayan abinci. Ana aiwatar da gyaran fuska ne kafin daga ranar 10-15 na magani kuma ya dogara da matakin glucose a cikin jini. Matsakaicin izini na yau da kullun da aka yarda wa yara shine 2000 MG, an kasu kashi 2-3.

Ga tsofaffi marasa lafiya, an zaɓi kashi na metformin daban-daban, ana saka idanu akan aikin koda.

Ina ɗaukar glucophage kowace rana, ba tare da tsangwama ba. Bearshen magani dole ne a sanar da likita.

Side effects

Yayin amfani da Glucofage, sakamako masu illa kamar:

• Rashin ci, tashin zuciya da amai, wani ɗanɗano mai narkewa a cikin raunin bakin, flatulence, zawo, ciwon ciki (yawanci yana faruwa ne a farkon jiyya kuma ya wuce kansu),
• Lactic adidosis (ana buƙatar karɓar magani), rashi na bitamin B12 saboda malabsorption (tare da tsawan magani),
• Megaloblastic anemia,
• Fashin fata.

Umarni na musamman

Yana yiwuwa a rage bayyanar sakamako na sakamako daga jijiyoyin hannu ta hanyar gudanar da maganin antacids, antispasmodics, ko kuma abubuwan atropine. Idan bayyanar cututtuka na dyspepti lokacin amfani da glucophage yana faruwa koyaushe, ya kamata a dakatar da maganin.

A lokacin jiyya, ya kamata ka daina shan barasa kuma kar a sha magunguna masu dauke da ethanol.

Tsarin magungunan ana amfani da magungunan sune Siofor 500, Siofor 850, Metfogamma 850, Metfogamma 500, Gliminfor, Bagomet, Gliformin, Metformin Richter, Vero-Metformin, Siofor 1000, Dianormet, Metospanin, Formmetin, Metformin, Glucofage Long, Metvogin 1000, Novo Pliva, Metadiene, Diaformin OD, Nova Met, Langerin, Metformin-Teva da Sofamet.

Sharuɗɗan da yanayin ajiya

Dangane da umarnin, ana bada shawarar Glucofage don adana shi a cikin wuri mai sanyi, amintaccen kariya daga danshi da hasken rana kai tsaye.

Rayuwar shiryayye na Glucofage 500 da 850 MG shine shekaru 5 daga ranar da aka ƙera, Glucofage 1000 da XR - shekaru 3.

An sami kuskure a cikin rubutun? Zaɓi shi kuma latsa Ctrl + Shigar.

Hotunan 3D

Bayanin sigar sashi

Allunan 500 da 850 MG: fararen, zagaye, biconvex, fim mai rufi, a sashin giciye - farin taro mai hadewa.

Allunan kwayoyi 1000 fararen, m, biconvex, an rufe shi da wani fim mai sutura, tare da daraja a bangarorin biyu da kuma zane "1000" a gefe guda, a sashin giciye - wani farin taro mai hade.

Pharmacodynamics

Metformin yana rage hyperglycemia ba tare da haifar da ci gaban hypoglycemia ba. Sabanin abubuwan da aka samo na sulfonylurea, ba ya tayar da rufin insulin kuma ba shi da tasirin hypoglycemic a cikin mutane masu lafiya. Theara hankalin mai karɓar mahaifa zuwa insulin da kuma amfani da glucose ta sel. Yana rage haɓakar glucose ta hanta ta hanyar hana gluconeogenesis da glycogenolysis. Yana jinkirta ɗaukar ciki na glucose. Metformin yana ƙarfafa haɗin glycogen ta hanyar yin aiki akan glycogen synthetase.

Capacityara ƙarfin jigilar kayayyaki na kowane nau'ikan jigilar jini na membrane. Bugu da ƙari, yana da tasiri mai amfani akan metabolism na lipid: yana rage abun ciki na jimlar cholesterol, LDL da triglycerides. Yayin shan metformin, nauyin jikin mai haƙuri ko dai ya kasance tsayayye ko yana raguwa da matsakaici. Karatuttukan asibiti sun kuma nuna tasirin maganin Glucofage ® don rigakafin kamuwa da cutar sankara a cikin marassa lafiya tare da ƙarin abubuwan haɗari don haɓakar ciwon sukari irin na 2, wanda yanayin canje-canjen rayuwa bai ba da damar isasshen sarrafa glycemic ba.

Pharmacokinetics

Orazantawa da rarrabawa. Bayan gudanar da baki, ana amfani da metformin daga ƙwayar narkewa. Cikakken bioavailability shine 50-60%. C_max (kimanin 2 μg / L ko 15 μmol) a cikin plasma an samu shi ne bayan awa 2.5. Tare da shigowa abinci abinci lokaci guda, yawan shan metformin zai ragu kuma yana jinkirta.

An rarraba Metformin cikin hanzari a cikin nama, kusan ba a ɗaura shi ga furotin plasma ba.

Metabolism da excretion. Yana cikin metabolized sosai ga rauni sosai kuma kodan ya keɓe shi. Bayyanar da metformin a cikin batutuwa masu ƙoshin lafiya shine 400 ml / min (sau 4 fiye da Cl creatinine), wanda ke nuna kasancewar tasirin tubular mai aiki. T_1/2 kamar awanni 6.5. A gazawar renal, T_1/2 yana ƙaruwa, akwai haɗarin tarin ƙwayoyi.

Alamun magungunan Glucofage ®

nau'in ciwon sukari na 2, musamman a cikin marasa lafiya tare da kiba, tare da rashin tasirin maganin abinci da aikin motsa jiki:

- a cikin manya, kamar yadda monotherapy ko a hade tare da wasu wakilai na baka hypoglycemic na bakin ko insulin,

- a cikin yara daga shekara 10 a matsayin maganin kashe azanci ko kuma a haɗe tare da insulin,

rigakafin kamuwa da ciwon sukari na 2 a cikin marasa lafiya da masu ciwon sukari tare da ƙarin abubuwan haɗari don haɓaka ciwon sukari na nau'in 2, wanda canje-canjen rayuwar ba su ba da izinin isasshen ikon sarrafa glycemic ba.

Haihuwa da lactation

Rashin daidaituwa na ciwon sukari mellitus a lokacin daukar ciki yana da alaƙa da haɓakar haɗarin rashin lahani na haihuwa da mutuwar haihuwa. Limitedarancin adadin bayanai sun nuna cewa shan metformin a cikin mata masu ciki baya ƙara haɗarin haɓakar nakasar haihuwar yara.

Lokacin da ake shirin yin juna biyu, haka kuma yayin da ake yin ciki a bango na shan metformin tare da ciwon suga da nau'in ciwon sukari na 2, yakamata a dakatar da maganin, kuma idan akwai nau'in ciwon sukari na 2, an wajabta maganin kansa. Wajibi ne a kula da abubuwan glucose a cikin jini na jini a matakin kusa da na al'ada don rage hadarin cutar tayin.

Metformin yakan shiga cikin madarar nono. Ba a lura da sakamako masu illa a cikin jarirai yayin shayarwa yayin shan metformin. Koyaya, saboda iyakance adadin bayanai, ba da shawarar amfani da miyagun ƙwayoyi lokacin shayarwa ba. Dole ne a yanke shawarar dakatar da shayarwa ta la'akari da amfanin shayarwa da kuma haɗarin haɗarin sakamako masu illa ga jariri.

Haɗa kai

Wakokin furotin da ke cikin Iodine: a bango na rashin aiki na koda na aiki a cikin marasa lafiya da ke fama da ciwon sukari, yin gwajin X-ray ta amfani da wakilan iodine mai dauke da sinadarin iodine na iya haifar da ci gaban acid din. Jiyya tare da Glucofage ® ya kamata a dakatar da sa'o'i 48 kafin ko a lokacin gwajin X-ray ta amfani da wakilai masu dauke da sinadarin iodine kuma bai kamata a sake farawa ba cikin awanni 48 bayan hakan, in dai an gano cewa aikin zakaran ya zama al'ada yayin gwajin.

Barasa: tare da matsanancin maye giya, haɗarin haɓaka lactic acidosis yana ƙaruwa, musamman idan akwai rashin abinci mai gina jiki, bin tsarin rage kalori, kuma tare da gazawar hanta. Yayin shan magungunan, ya kamata a guje wa barasa da kwayoyi masu ɗauke da ethanol.

Haɗuwa yana buƙatar taka tsantsan

Danazole: Ba a ba da shawarar gudanar da lokaci daya dana danazol don guje wa tasirin ƙarshen rayuwar ba. Idan magani tare da danazol ya zama dole kuma bayan dakatar da ƙarshen, ana buƙatar daidaita sashi na magani Glucofage ® a ƙarƙashin kulawar tattarawar glucose a cikin jini.

Chlorpromazine: lokacin da aka karɓa cikin manyan allurai (100 MG / rana) yana ƙaruwa da yawaitar glucose a cikin jini, yana rage ƙaddamar da insulin. A cikin maganin rigakafin ƙwayar cuta da kuma bayan dakatar da ƙarshen, ana buƙatar daidaita sashi a ƙarƙashin kulawar maida hankali na glucose jini.

Tsarin GKS da aikin gida rage haƙuri haƙuri, ƙara taro na glucose a cikin jini, wani lokacin haifar da ketosis. A cikin lura da corticosteroids kuma bayan dakatar da ci na ƙarshen, ana buƙatar daidaita sashi na ƙwayar Glucofage ® ƙarƙashin kula da yawan glucose jini.

Rashin daidaito: lokaci guda yin amfani da madauki diuretics zai iya haifar da haɓakar lactic acidosis saboda gazawar aiki na aiki. Bai kamata a ƙayyade Glucofage ® idan Cl creatinine yana ƙasa da 60 ml / min.

Lura β₂-adrenomimetics: ƙara yawan haɗuwar glucose a cikin jini saboda yawan motsawar β₂-adarinya. A wannan yanayin, ya zama dole don sarrafa tattarawar glucose a cikin jini. Idan ya cancanta, ana bada shawarar yin insulin.

Tare da yin amfani da magungunan da ke sama lokaci guda, za a buƙaci ƙarin sa ido kan yawan glucose na jini, musamman a farkon jiyya. Idan ya cancanta, za a iya daidaita adadin metformin yayin jiyya da kuma bayan ƙarewa.

Magungunan rigakafi, banda na ACE inhibitors, na iya ruguza glucose na jini. Idan ya cancanta, ya kamata a daidaita sashi na metformin.

Tare da amfani da magani na lokaci daya Glucofage ® tare da abubuwan da suka samo asali na insulin, da insulin, acarbose, salicylates, haɓakar ƙwayar cuta yana yiwuwa.

Nifedipine yana ƙara sha da C_max metformin.

Cationic kwayoyi (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, trimethoprim da vancomycin) wanda aka ɓoye a cikin tubules na koda yana gasa tare da metformin don tsarin jigilar tubular kuma yana iya haifar da karuwa a cikin C_max .

Sashi da gudanarwa

Monotherapy da magani tare a hade tare da sauran wakilai na baka hypoglycemic na bakin mutum don ciwon sukari na 2. Yawan farawa na yau da kullun shine 500 ko 850 mg sau 2-3 a rana bayan ko lokacin abinci.

Kowane kwana na 10-15, ana bada shawara don daidaita sashi gwargwadon sakamakon aunawa da yawaitar glucose a cikin jini. Rage hawa a kashi na taimaka wajan rage tasirin sakamako daga hanji.

Adadin kulawa da miyagun ƙwayoyi yawanci 1500-2000 mg / rana. Don rage tasirin sakamako daga cututtukan gastrointestinal, ya kamata a raba kashi na yau da kullum zuwa kashi 2-3. Matsakaicin adadin shine 3000 MG / rana, ya kasu kashi uku.

Marasa lafiya suna ɗaukar metformin a cikin allurai na 2000-3000 mg / day zasu iya canjawa zuwa miyagun ƙwayoyi Glucofage ® 1000 mg. Matsakaicin shawarar da aka ba da shawarar ita ce 3000 MG / rana, ya kasu kashi uku.

Game da batun canji daga shan wani wakili mai zubar da jini: dole ne ku daina shan wani magani kuma ku fara shan Glucofage drug a kashi da aka nuna a sama.

Haɗuwa da insulin. Don cimma ingantaccen iko na glucose na jini, metformin da insulin a cikin marasa lafiya da ke dauke da ciwon sukari na 2 ana iya amfani dasu azaman hanyar haɗuwa. Yawancin farawa na yau da kullun na Glucofage 500 shine 500 ko 850 mg sau 2-3 a rana, yayin da aka zaɓi kashi na insulin dangane da haɗuwa da glucose a cikin jini.

Monotherapy don maganin ciwon suga. Yawan da aka saba dashi shine 1000-1700 mg / rana bayan ko lokacin abinci, an kasu kashi biyu.

An ba da shawarar yin sarrafa glycemic a kai a kai don tantance buƙatar ƙarin amfani da miyagun ƙwayoyi.

Rashin wahala. Za'a iya amfani da Metformin a cikin marasa lafiya tare da gazawar matsakaiciyar matsakaici (Cl creatinine 45-55 ml / min) kawai a cikin rashin yanayin da zai iya ƙara haɗarin lactic acidosis.

Marasa lafiya tare da Cl creatinine 45-55 ml / min. Maganin farko shine 500 ko 850 mg sau ɗaya a rana.Matsakaicin adadin shine 1000 mg / rana, an kasu kashi biyu.

Ya kamata a kula da aikin azabtarwa a hankali (kowace watanni 3-6).

Idan Cl creatinine yana ƙasa da 45 ml / min, ya kamata a dakatar da maganin nan da nan.

Tsufa. Saboda yiwuwar raguwa a aikin na koda, dole ne a zaɓi kashi na metformin a ƙarƙashin kulawar yau da kullun akan alamun alamun aiki (ƙayyade taro na creatinine a cikin ƙwayar jini a kalla sau 2 a shekara).

Yara da matasa

A cikin yara daga shekaru 10, ana iya amfani da Glucofage ® duka a cikin maganin monotherapy kuma a hade tare da insulin. Yawan farawa na yau da kullun shine 500 ko 850 MG 1 sau ɗaya kowace rana bayan ko lokacin abinci. Bayan kwanaki 10-15, dole ne a daidaita adadin gwargwadon yawan tattarawar glucose jini. Matsakaicin adadin yau da kullun shine 2000 MG, ya kasu kashi 2-3.

Ya kamata a sha Glucofage ® kowace rana, ba tare da tsangwama ba. Idan an daina kulawa, mai haƙuri ya kamata ya sanar da likita.

Yawan abin sama da ya kamata

Lokacin da aka yi amfani da metformin a cikin kashi har zuwa 85 g (sau 42.5 mafi yawan maganin yau da kullun), ba a lura da ci gaban hypoglycemia ba. Koyaya, a wannan yanayin, an lura da ci gaban lactic acidosis. Mahimmancin wucewa ko abubuwan haɗari masu haɗari na iya haifar da haɓakar lactic acidosis (duba "Umarni na Musamman").

Jiyya: Idan akwai alamun lactic acidosis, magani tare da miyagun ƙwayoyi ya kamata a dakatar da shi nan da nan, ya kamata a kwantar da mai haƙuri cikin gaggawa kuma, bayan ya ƙaddara maida hankali kan maganin lactate, ya kamata a fayyace cutar. Mafi girman gwargwado don cire lactate da metformin daga jiki shine hemodialysis. Hakanan ana gudanar da aikin tiyata.

Mai masana'anta

Duk matakan matakai na samarwa, gami da bayar da ingantaccen iko. Merck Sante SAAS, Faransa.

Adireshin gidan yanar gizon samarwa: Centre de Producion Semois, 2, rue du Pressoir Ver, 45400, Semois, Faransa.

Ko kuma game da kunshin magungunan LLC Nanolek:

Ctionirƙirar tsari na gama abinci da kayan marufi (marufi na farko) Merck Santé SAAS, Faransa. Semois Centreis na samar da kayayyaki, 2 rue du Pressoire Ver, Semois 45400, Faransa.

Sakandare (marufi na mabukaci) da bayarda ingantaccen iko: Nanolek LLC, Russia.

612079, Yankin Kirov, gundumar Orichevsky, garin Levintsy, Cibiyar Biomedical "NANOLEK"

Duk matakan matakai na samarwa, gami da bayar da ingantaccen iko. Merck S.L., Spain.

Adireshin wurin samarwa: Polygon Merck, 08100 Mollet Del Valles, Barcelona, ​​Spain.

Mai riƙe da takardar shaidar rijista: Merck Santé SAAS, Faransa.

Da'awar Abokan Ciniki da bayani game da mummunan lamari yakamata a aika zuwa adireshin LLC Merk: 115054, Moscow, ul. Gashi, 35.

Waya: (495) 937-33-04, (495) 937-33-05.

Rayuwar shiryayye na miyagun ƙwayoyi Glucofage ®

500 MG allunan da aka saka a fim - 5 years.

500 MG allunan da aka saka a fim - 5 years.

Allunan mai rufi tare da fim fim na 850 MG - 5 years.

Allunan mai rufi tare da fim fim na 850 MG - 5 years.

allunan da aka sanya fim - 1000 mg - 3 years.

allunan da aka sanya fim - 1000 mg - 3 years.

Kada kayi amfani bayan ranar karewa wanda aka nuna akan kunshin.

Glucophage. Sashi

Allunan don maganin baka (baka).

Ana amfani dashi azaman maganin monotherapy ko maganin haɗuwa (tare da alƙawarin sauran wakilai na hypoglycemic).

Matakin farko shine 500 MG na miyagun ƙwayoyi, a wasu yanayi - 850 MG (da safe, da tsakar rana, da maraice a cikakken ciki).

A nan gaba, kashi yana ƙaruwa (kamar yadda ake buƙata kuma kawai bayan tuntuɓar likita).

Don kula da tasirin warkewar ƙwayar, ana buƙatar mafi yawan kullun - daga 1500 zuwa 2000 MG. An haramta sashi ya wuce MG 3000 da sama!

Yawan adadin yau da kullun ya kasu kashi uku ko sau hudu, wanda ya zama dole don hana haɗarin cutarwar sakamako.

Lura Wajibi ne a kara adadin yau da kullun tsawon mako guda, a hankali, don guje wa cutarwa. Wadancan marasa lafiya waɗanda suka sha magungunan ƙwayoyi tare da metformin mai aiki a cikin adadin daga 2000 zuwa 3000 MG, allunan Glucofage ya kamata a sha a sashi na 1000 MG kowace rana.

Idan kuna shirin ƙin shan wasu kwayoyi waɗanda ke shafar abubuwan ƙira na hypoglycemic, ya kamata ku fara shan Allunan Glucofage a cikin mafi ƙarancin shawarar, a cikin hanyar monotherapy.

Glucophage da insulin

Idan kana buƙatar ƙarin insulin, ana amfani da ƙarshen kawai a sashi wanda likita ya ɗaga.

Jiyya tare da metamorphine da insulin ya zama dole don cimma wani adadin glucose a cikin jini. Algorithm na yau da kullun shine kwamfutar hannu 500 MG (ƙasa da sau 850 MG) sau biyu ko sau uku a rana.

Sashi don yara da matasa

Daga shekaru goma zuwa tsoho - azaman magani mai zaman kanta, ko kuma wani ɓangare na cikakken magani (tare da insulin).

Mafi kyawun farashi (guda ɗaya) na yau da kullun shine kwamfutar hannu ɗaya (500 ko 850 MG.), Wanda aka ɗauka tare da abinci. An ba da izinin shan maganin don rabin sa'a bayan cin abinci.

Dangane da wani adadin glucose a cikin jini, an daidaita matakan maganin a hankali (layin - aƙalla ɗaya zuwa makonni biyu). An hana kwayar cutar ga yara karuwa (fiye da 2000 MG). Ya kamata a raba magunguna zuwa kashi uku, aƙalla allurai biyu.

Haɗe-haɗe ba a yarda da kowane yanayi ba

X-ray bambanci wakilai (tare da abun ciki aidin). Nazarin rediyo na iya zama mai kawo ci gaban lactic acidosis ga mai haƙuri da alamomin cututtukan mellitus.

Glucophage ya daina ɗaukar kwanaki uku kafin binciken kuma ba a sake ɗaukar shi bayan kwana uku bayan shi (gaba ɗaya, tare da ranar binciken - mako guda). Idan aikin dan adam bisa ga sakamakon ya kasance mai gamsarwa, wannan lokacin yana ƙaruwa - har sai an dawo da jikin gaba ɗaya zuwa al'ada.

Zai zama mai kyau mu guji amfani da miyagun ƙwayoyi idan akwai adadi mai yawa na ethanol a jiki (ƙonewa mai sa maye). Haɗin wannan yana haifar da haifar da yanayi don bayyanar cututtuka na lactic acidosis. Lowarancin kalori ko ƙarancin abinci mai gina jiki, musamman akan asarar hanta, yana ƙara haɗarin wannan haɗarin.

Kammalawa Idan mai haƙuri ya ɗauki miyagun ƙwayoyi, dole ne ya yi watsi da amfani da kowane irin barasa, gami da kwayoyi waɗanda suka haɗa da ethanol.

Haɗuwa da ke buƙatar taka tsantsan

Danazole Yin amfani da Glucofage da Danazole lokaci guda ba wanda ake so ba. Danazole yana da haɗari tare da tasirin hyperglycemic. Idan ba zai yiwu a ƙi shi ba saboda dalilai daban-daban, za a buƙaci cikakken daidaita sakin jiki na Glucofage da saka idanu akai-akai na matakan glucose na jini.

Chlorpromazine a cikin babban adadin yau da kullun (fiye da 100 MG), wanda ke taimakawa haɓaka yawan glucose a cikin jini da rage yiwuwar sakin insulin. Ana buƙatar daidaita daidaituwa na kashi.

Kwayarwa. Dole ne a yarda da kula da marasa lafiya tare da maganin ƙin ƙwayar cuta tare da likita. Gyaran matakan Glucofage ya zama dole gwargwadon matakin glucose a cikin jini.

GCS (glucocorticosteroids) mummunan tasiri na haƙuri na glucose - matakin glucose na jini a cikin jini ya tashi, wanda zai haifar da ketosis. A irin waɗannan halayen, yakamata a ɗauki Glucophage dangane da takamaiman adadin glucose a cikin jini.

Idan aka yi amfani da maganin dip, idan aka dauke su guda biyu tare da glucophage suna haifar da hadarin lactic acidosis. Tare da CC daga 60 ml / min da ƙasa, glucophage ba a wajabta shi ba.

Adrenomimetics. Lokacin shan Bon 2-adrenergic agonists, matakin glucose a cikin jiki shima ya tashi, wanda wani lokacin yana buƙatar ƙarin allurai na insulin ga mara haƙuri.

ACE inhibitors da duk magungunan antihypertensive suna buƙatar daidaita kashi na metformin.

Sulfonylurea, insulin, acarbose da salicylates lokacin da aka haɗu tare da glucophage zasu iya haifar da hypoglycemia.

Haihuwa da lactation. Siffofin .aukar wurare

Bai kamata a sha Glucophage yayin daukar ciki ba.

Cutar zazzabin cizon sauro mai yiwuwa cuta ce a cikin tayi. A cikin dogon lokaci - mutuwar haihuwa. Idan mace ta yi shirin yin juna biyu ko kuma tana cikin matakan farko na ciki, to ya zama dole ki guba shan maganin. Madadin haka, ana wajabta maganin insulin don kula da adadin yawan glucose da ake buƙata.

Side effects

A kananan kashi na lactic acidosis. Yin amfani da glucophage na dogon lokaci na iya haifar da raguwa a cikin yawan ƙwayar bitamin B12. Ya kamata a yi la’akari da matsalar a cikin marasa lafiya da alamun cutar megaloblastic anaemia.

Take hakkin dandano.

• Hare-hare na tashin zuciya da amai.
• Zawo gudawa
• Ciwon ciki.
• Rashin ci.

Hankali! Irin waɗannan alamun suna halayyar kawai a cikin 'yan kwanakin farko da makonni na shan miyagun ƙwayoyi. Bayan haka, abubuwanda zasu haifar da kansu.

Ofimar erythema, itching kadan, wani lokacin fatar fata.

Cutar hanta da hancin biliary

Da wuya a lura da maganganun da ke tattare da aiki na hanta, har sau ƙasa - alamun bayyanar hepatitis. Wajibi ne a soke metformin, wanda zai iya lalata sakamako na gaba ɗaya.

Ga marasa lafiya. Bayani mai mahimmanci akan lactic acidosis

Lactic acidosis ba cuta ce ta kowa ba. Koyaya, yakamata a dauki duk matakan da suka wajaba don kawar da haɗarin bayyanarsa, tunda cutar sanadiyyar cutar halayen cuta tana tattare da rikice rikice da kuma yawan mace-mace.

Lactic acidosis yawanci ya bayyana kansa a cikin marasa lafiya suna shan metamorphine waɗanda ke da mummunan rauni game da koda saboda ciwon sukari mellitus.

Sauran abubuwan haɗari sun haɗa da:

• Bayyanar cututtukan cututtukan sukari.
• Bayyanar ketosis.
• Tsawon lokaci na rashin abinci mai gina jiki.
• Matsanancin matakai na shan giya.
• Alamun hypoxia.

Yana da mahimmanci. Wajibi ne a kula da alamun farkon matakin lactic acidosis. Wannan alama ce ta halayyar kwayar halitta, wanda aka bayyana a cikin jijiyar wuya, dyspepsia, ciwon ciki da kuma babban asthenia. Acidotic dyspnea da hypothermia, kamar yadda alamu suka gabata gabanin auma, suma suna nuna cutar. Duk wata alama ta metabolic acidosis sune tushen dakatar da miyagun ƙwayoyi nan da nan da kuma neman likita na gaggawa.

Glucophage yayin aikin tiyata

Idan an tsara mara lafiyar don tiyata, ya kamata a daina barin metformin aƙalla kwanaki uku kafin ranar tiyata. Za a sake dawo da magunguna ne kawai bayan nazarin aikin aikin koda, aikin da aka iske mai gamsarwa. A wannan yanayin, ana iya ɗaukar Glucofage a rana ta huɗu bayan tiyata.

Gwajin aikin koda

Metformin an cire shi ta hanyar kodan, don haka farkon magani yana da alaƙa koyaushe tare da gwaje-gwaje na dakin gwaje-gwaje (ƙididdigar halittarine). Ga wadanda aikinsu ba naƙasa ba, ya isa su gudanar da karatun likita sau ɗaya a shekara. Ga mutanen da ke cikin haɗari, kazalika da tsofaffi marasa lafiya, ƙaddarar QC (adadin creatinine) dole ne a yi har sau hudu a shekara.

Idan an wajabta maganin diuretics da antihypertensive don tsofaffi, lalacewar koda na iya faruwa, wanda ke nufin kai tsaye likitoci suna buƙatar kulawa da hankali.

Glucophage a cikin ilimin yara

Ga yara, ana yin magani ne kawai lokacin da aka tabbatar da bayyanar cutar yayin gwajin lafiyar gaba ɗaya.

Nazarin asibiti kuma ya tabbatar da amincin ga yaro (girma da balaga). Ana buƙatar kulawa ta yau da kullun a cikin kulawa da yara da matasa.

Kariya da aminci

Sarrafa abincin abinci wanda yakamata a ƙona carbohydrates a cikin wadataccen adadi kuma a ko'ina.

Idan kun yi kiba, za ku iya ci gaba da rage yawan abincin da ake amfani da shi, amma a cikin adadin 1000 - 1500 kcal ne ake bayarwa na yau da kullun.

Yana da mahimmanci. Gwajin gwaje-gwaje na yau da kullun don kulawa ya kamata ya zama doka ta doka ga duk waɗanda ke shan ƙwayar Glucofage.

Glucofage da tuki

Amfani da miyagun ƙwayoyi ba shi da alaƙa da matsalar tuki motoci ko hanyoyin aiki. Amma rikitaccen magani na iya zama haɗari ga haɗarin hypoglycemia. A wannan yanayin, kuna buƙatar tuntuɓi likita.

Magunguna tare da aikin hypoglycemic na iya tasiri sosai ga jikin tare da.

Ofaya daga cikin waɗannan magungunan shine, contraindications da sakamako masu illa waɗanda ba a iya kwatanta su da tasirinsa mai kyau.

Wannan magani ne mai mahimmanci tare da, wanda zai iya inganta yanayin mai ciwon sukari sosai.

Glucophage shine maganin rage sukari wanda aka wajabta don jure insulin. Abun da ke cikin miyagun ƙwayoyi shine hydrochloride.

Allunan glucophage 750 MG

Sakamakon hanawar gluconeogenesis a cikin hanta, sinadarin yana rage sukari jini, yana inganta lipolysis, kuma yana caccakar shaye-shayen glucose a cikin narkewa.

Sakamakon kayan aikin hypoglycemic, an sanya miyagun ƙwayoyi don cututtukan masu zuwa:

Zan iya yin wasanni lokacin shan kwayoyin?

A cewar binciken da aka yi kwanan nan, a lokacin shan maganin ba a sabunta shi ba. A karshen karni na karshe, an sami ra'ayi sabanin haka. Hypoglycemic wakili tare da karuwar lodi ya haifar da lactic acidosis.

An haramta amfani da tushen-Metformin da concomitant.

Magunguna na ƙarni na farko sun haifar da sakamako masu illa, gami da haɗarin ƙirƙira. Wannan yanayin rayuwa ne mai haɗari wanda lactic acid a cikin jiki ya kai matakan girma.

Yawan cakulan lactate ana danganta shi da keta hadarin acid-base a cikin kyallen da kuma karancin insulin a jiki, aikin shi shine ya rushe glucose. Ba tare da taimakon gaggawa na likita ba, mutum a wannan yanayin. Tare da haɓaka fasahohin kimiyyar magunguna, an rage tasirin sakamako na amfani da hypoglycemic.

• Kada a bada izinin bushewa,
• kana buƙatar saka idanu kan dacewar numfashi yayin horo,
• horarwa yakamata ya zama mai tsari, tare da hutu na tilas don murmurewa,
• Ya kamata karuwa a hankali
• idan kun ji sauti na konewa a cikin jijiyar tsoka, ya kamata ku rage yawan motsawar,
• Ya kamata a daidaita tare da ingantaccen abun ciki na bitamin da ma'adanai, gami da magnesium, bitamin B,
• Abincin yakamata ya haɗa da mahimmancin adadin kitse mai lafiya. Suna taimakawa rushe lactic acid.

Glucophage da gina jiki

Jikin ɗan adam yana amfani da kitse kuma azaman tushen kuzari.

Sunadarai suna kama da kayan gini saboda su abubuwa ne masu mahimmanci na gina taro na tsoka.

A cikin rashin carbohydrates, jiki yana amfani da kitsen don makamashi, wanda ke haifar da raguwar kitsen jiki da samuwar taimako na tsoka. Saboda haka, jigon jiki yana manne da bushewar jiki.

Hanyar aikin Glucophage shine hana aiwatar da gluconeogenesis, ta hanyar da ake samar da glucose a cikin jiki.

Magungunan sun shiga tsakani tare da shanyewar carbohydrates, wanda ya dace da ayyukan da mai gina jikin ke bi. Baya ga rage gluconeogenesis, miyagun ƙwayoyi suna ƙaruwa juriya insulin, rage lolesterol, triglycerides, lipoproteins.

Jikin bodybuil na daga cikin wadanda suka fara amfani da magungunan cututtukan jini domin kona mai. Ayyukan miyagun ƙwayoyi ya yi daidai da aikin mai tsere. Abun hypoglycemic na iya taimakawa wajen ci gaba da rage karancin abinci da kuma cimma sakamakon wasanni cikin kankanen lokaci.

Tasiri akan kodan

Magungunan ƙwaƙwalwar ƙwayar cuta yana shafar kodan kai tsaye. Mai aiki mai aiki ba metabolized bane kuma an raba shi da kodan bashi canzawa.

Tare da rashin isasshen aiki na keɓaɓɓiyar, abu mai aiki yana talaucewa, ƙarancin keɓaɓɓe yana raguwa, wanda ke ba da gudummawa ga tarawa a cikin kyallen takarda.

Yayin aikin likita, kulawa akai-akai game da tace ƙasa da adadin sukari a cikin jini ya zama dole. Sakamakon tasirin mai abu akan aikin kodan, ba a ba da shawarar shan magani don gazawar renal.

Tasiri kan haila

Glucophage ba magani bane na hormonal kuma baya shafar zubar jinin haila kai tsaye. Zuwa wani yanayi, zai iya yin tasiri akan yanayin kwayar.

Magungunan yana ƙaruwa da juriya na insulin kuma yana shafar rikice-rikice na rayuwa, wanda shine hali na polycystic.

Magungunan hypoglycemic ana ba da umarnin sau da yawa ga marasa lafiya da ke fama da anovulation, wahala da hirsutism. Anyi nasarar amfani da dawo da hankalin insulin cikin aikin magance rashin haihuwa wanda cutawar kwayar ta haifar.

Sakamakon aikinta akan farji, tsarin tsari da tsawaita amfani da maganin hypoglycemic magani kai tsaye yana shafar aikin ovaries. Tsarin haila na iya juyawa.

Shin suna samun taushi daga maganin?

Ma'aikacin hypoglycemic, tare da abinci mai dacewa, ba zai iya haifar da kiba ba, tunda yana toshe ragowar carbohydrates a jiki. A miyagun ƙwayoyi zai iya inganta jiki ta metabolism mayar da martani ga.

Glucophage yana taimakawa wajen dawo da furotin da mai, wanda ke haifar da asara mai nauyi.

Toari ga sakamako na hypoglycemic, miyagun ƙwayoyi sun toshe asarar kitse da tarawa a cikin hanta. Sau da yawa, lokacin amfani da miyagun ƙwayoyi, ci abinci yana raguwa, wanda ke ba shi sauƙin sarrafa abincin.

Magungunan ba shi da tasiri kai tsaye akan ƙwayar adipose. Abin sani kawai yana katsewa tare da ɗaukar abubuwan da ke dauke da carbohydrate, rage yawan sukari na jini da haɓaka martani ga insulin.

Amfani da glucophage ba panacea bane don kiba, yakamata ku lura da ƙuntatawa akan amfani da carbohydrates mai sauƙi kuma kuyi aiki da jiki. Tunda abu mai aiki yana shafar aikin koda, bin umarni wajibi ne.