Adebit: umarnin don amfani, farashi, dubawar likitoci da marasa lafiya

Ya kamata a tsara takaddara a hade tare da diuretics (musamman tare da abubuwan da ke cikin thiazide). Saboda haɗarin lactic acidosis, ya kamata a yi gwajin jini kowace wata shida, kuma ya kamata a sa ido a kan aikin hanta da koda. Kafin tiyata, sauyawa zuwa ilimin insulin ya zama dole. A lokacin jiyya, ba za ku iya shan barasa ba, saboda A wasu halaye, rashin haƙuri na iya faruwa.

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Neman Bayanan Bincike na Yanzu, ‰

Takaddun shaida na Adebit

• S-8-242 N2016

Shafin gidan yanar gizon kamfanin RLS ®. Babban encyclopedia na kwayoyi da kayayyaki na kantin magani na Rasha yanar-gizo. Kundin adireshi na Rlsnet.ru yana ba masu amfani damar samun umarni, farashi da kwatancin magunguna, kayan abinci, na’urorin likitanci, na’urorin likita da sauran kayayyakin. Jagorar magunguna ta hada da bayani kan abun da ya kunsa da kuma irin sakin, aikin pharmacological, alamu don amfani, contraindications, sakamako masu illa, hulɗa da magunguna, hanyar amfani da magunguna, kamfanonin harhada magunguna. Takaddun magungunan ya ƙunshi farashin magunguna da samfuran magunguna a Moscow da sauran biranen Rasha.

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Ba a ba da izinin amfani da kayan kayan kasuwanci ba.

Bayanin an yi nufin ne don ƙwararrun likitoci.

Adebit - umarni, farashi, sake dubawa da kuma alamun maganin

Adebit - wakili na maganin antidiabetic don maganin baka don maganin marasa lafiyar insulin. Ba ya haifar da hypoglycemia a cikin mutane masu lafiya; ana iya tsara shi tare da abubuwan da suka samo asali na maganin sulfonylurea.

Tasirin warkewa

Magungunan maganin antidi da na baka na ƙungiyar biguanide. Mai ikon haɓaka amfani da glucose da haɓakar anaerobic glycolysis.

Adebit ba ya haifar da hypoglycemia a cikin mutane masu lafiya. Zai yiwu a tsara shi tare da wakilai na maganin antidiabetic na nau'in sulfonamide.

• Nau'in nau'in ciwon sukari na 2 a cikin tsofaffi, a haɗuwa da jiyya tare da abubuwan ƙira na sulfonylurea, yayin da suke ci gaba da samar da insulin ƙwayoyin cuta.
• Kiba a cikin ciwon sukari.
• Rashin tsayayyen sukari metabolism (a hade tare da insulin).

Contraindications

Acidosis ko gano abubuwan da ke haifar da lactic acidosis: embolism na huhu, gazawar zuciya, nakasa ko na aikin jijiya, matsanancin ciwo, cututtukan da ke ɗauka, ƙwayar cuta, ƙwanƙwasa cuta, zazzabi, hypovolemia, cututtukan ƙwayar cuta, amfani da diuretics,shiri don tiyata da yanayi bayan tiyata, tsufa, ciki.

Hanyar aikace-aikacen

Aikace-aikacen da sashi yana ƙaddara ta hanyar halartar likita. Maganin farko shine daga kwayar 100-150 kowace rana (har sau 3 1 kwamfutar hannu), tare da karamin adadin ruwan tsaka tsaki bayan cin abinci.

Nan gaba, gwargwadon yanayin mai haƙuri, ana iya ƙara yawan kashi ta 1 kwamfutar hannu kowane kwana 2 ko 4. Matsakaicin adadin kowace rana shine 300 MG ko allunan 6, waɗanda aka kasu kashi 3 ko 4.

Sashi na tabbatarwa yawanci shine 200 mg kowace rana (4 Allunan).

Side sakamako

• Ciwon hanci, amai, gudawa, asarar ci da ƙarfe a bakin. Wadannan gunaguni suna yiwuwa yayin ɗaukar magani a kan komai a ciki, sun ɓace bayan raguwar kashi na ɗan lokaci.
• Malabsorption na bitamin B12, lactic acidosis, idiosyncrasy. Haɓaka irin wannan yanayi yana yiwuwa tare da rashin kula da contraindications ga miyagun ƙwayoyi.

Umarni na musamman

Yana buƙatar yin amfani da miyagun ƙwayoyi tare da diuretics, abubuwan thiazide (saboda haɗarin lactic acidosis, hypovolemia), rigakafin baka (saboda raguwar aiki a cikin juna), corticosteroids (suna rage tasirin Adebit), magungunan da ke kara lokacin coagulation na jini (Adebit) yana inganta tasirinsu).

A cikin lura da Adebite, saka idanu akan hoto na yau da kullun na jini, kazalika da ayyukan kodan da hanta ya zama dole, wanda ke hade da haɗarin haɓakar lactic acidosis.

Idan kun sami rashin jin daɗi a cikin jijiyoyin, jijiya, numfashi mai saurin motsa jiki, shawarci likita nan da nan. M tsananin riko da abinci da kuma cikakken kebewar giya, kamar yadda wasu lokuta ake lura da rashin haƙuri.

A cikin marasa lafiya da rashin haƙuri na lactose, za'a iya samun matsaloli tare da narkewar ƙwayar cuta saboda abubuwan da ke ciki a cikin allunan.

Ana ajiye "Adebit" a zazzabi a ɗakin, wanda aka zubar bayan karewar lokacin da aka nuna akan kunshin. Rayuwar shiryayye - shekaru 5.

RUWAN DARIQA

Aikin magunguna

Tasirin rage sukari na Adebit ya ƙunshi inganta haɓaka cikin jiki da ƙwaƙwalwar ƙwayar tsoka (musamman ƙwayar tsoka), yana rage jinkirin glucose a cikin ƙananan hanji da canjinsa zuwa cikin jini, da kuma toshe gluconeogenesis a cikin hanta. Magungunan yana kunna anaerobic glycolysis, yana haɓaka yiwuwar ƙwayoyin sel zuwa insulin.

Adebit yana haifar da ƙarancin tasiri, rage abinci, wanda ke sauƙaƙa rage cin abinci kuma yana taimakawa rage nauyi cikin kiba. Hasarin yana da kayan thrombolytic.

Tasirin warkewa yana farawa bayan sa'o'i 2-4, yana kaiwa matsakaici bayan sa'o'i 5. Jimlar aikin aikin ya kai awowi 8. Abun yana da cikakken bioavailability, yana saurin narkewa cikin narkewa. An fitar dashi ta cikin kodan.

• nau'in ciwon sukari na 2 a cikin manya, a hade tare da sulfonylureas tare da isasshen tasiri
• nau'in ciwon sukari na 1, a haɗe tare da insulin, in babu ingantaccen metabolism na sukari
• kiba.

Yadda ake ɗaukar ADEBIT

Yarda da abinci sau biyu a rana: safe da maraice. Maganin farko shine 100-150 MG (1 kwamfutar hannu 1 sau 3 a rana). Adadin yau da kullun ya dace da sukari na jini, amma bai wuce 300 mg / rana ba (allunan 6 a allurai uku). Siyarwar tabbatarwa shine allunan 4 a kowace rana.

Don lura da kiba, ana ƙaddara adadin kullun na 100 MG.

Yin hulɗa tare da sauran abubuwa

Ana iya amfani da Adebit a hade tare da insulin, ƙwayar ta inganta kuma yana tsawaita sakamako. Abubuwa kamar su chlorpromazine, hormones thyroid, corticosteroids, da diuretics suna rage tasirin sugar na ragewa a cikin Adebit.Salicylates, MAO inhibitors da shirye-shiryen sulfonylurea - haɓaka.

Amfani da ciki tare da rigakafin hormonal yana raunana sakamakon magungunan biyu. Adebit yana haɓaka aikin thrombolytics.

Ya kamata a sami Adebit ci tare da saka idanu akai-akai na glucose jini da kuma lura da aikin koda.

Ciniki 24 MG - umarnin don amfani, farashi, sake dubawa, analogues

Sannu kowa da kowa! Mun ci gaba da sake nazarin magungunan, wanda ya fara anan tare da analogues na Zovirax, ya ci gaba "a nan" ta hanyar labarin a enterofuril, sannan akwai ta analogs na Sinupret, sannan kuma a cikin sashe na "Gabatarwa zuwa Lafiya mai Lafiya". A yau taken mu shine: "Betaserc 24 MG - umarnin don amfani, farashi, sake dubawa, analogues". A kan wannan batun, Na riga na rubuta "nan" Wannan cigaba ne.

Cutar cututtukan kunne na ciki, kamar auditory jijiya neuritis ko labyrinthitis, wanda ke haifar da asarar ji da danshi. Ba za su iya faruwa ba kawai a cikin tsufa, har ma a cikin matasa bayan kumburi na tsakiyar kunne ko shan magungunan ototoxic.

Ba shi yiwuwa a maido da aikin ƙwaƙwalwar ƙwaƙwalwar ƙwayar cuta idan akwai mummunan lalacewa ta jiki. Ana iya magance irin waɗannan matsalolin ne kawai cikin lokaci mai zuwa.Idan aka fara cutar, to aƙalla a dakatar da ayyukan jijiyoyin ƙwayar cuta da hana shi ci gaba, ana amfani da magunguna waɗanda ke haɓaka trophism na kunne na ciki.

Suchaya daga cikin irin waɗannan magungunan shine betaserk 24 MG, umarnin don amfani, farashi, sake dubawa, analogues wanda za a tattauna a wannan labarin.

1.1 Sanadin da alamun cututtukan kunne na ciki

Bangaren sashen binciken ɗabi'ar da nazarcin ɗan adam ya fara a cikin ɓarke ​​da zazzaɓi. Akwai kwayoyin halitta masu tsinkaye waɗanda suke tsinkayar sauti mara sauti da gantsin kai, sabili da haka suna da alhakin ji da daidaitawa. Cututtuka na kunnuwan ciki duka biyu na kumburi da degenerative.

Farkon abin ya faru ne sakamakon shigarwar kwayoyin cuta daga kunne ta tsakiya a yayin kamuwa da cuta ko kwayan cuta. Dalili na biyu na iya zama damuwa da damuwa ko mutuwar jijiya saboda cututtukan jijiyoyin jiki, rauni mai rauni ko yawan amfani. magungunan kwayar cutar ototoxic.

Bayyanar cutar lalacewa ga kunnuwan ciki shine da farko rashin bacci, haka kuma amo da kararrawa a cikin kunnuwa, jin nauyi, tashin zuciya, ko rashin daidaituwa. Amma yana da daraja a duba cewa idan mara lafiyar yana azabtar da shi ta hanyar jinshi, kuma ji na al'ada ne, to dizziness, a matsayin mai mulkin, ba shi da alaƙa da kunnen ciki.

1.2 ciplesa'idojin magance cututtukan kunne na ciki

Yana da mahimmanci ga marasa lafiya su fahimci cewa idan ƙwayoyin azanci sun mutu ba tare da izini ba, to, magani ba zai taimaka musamman ba. Sabili da haka, kuna buƙatar fara shi da wuri-wuri: lokacin da alamun farko na rauni na ji da daidaitawa suka faru.

A cikin hanyoyin kumburi, an wajabta maganin rigakafi don magani, amma ba kawai ototoxic ba, kazalika da magungunan anti-kumburi da ke sauƙaƙa edema (diuretics, corticosteroids, hypertonic cure, antihistamines).

Don inganta ƙwayoyin trophic, ana bada shawarar multivitamins, therapy detoxification da kwayoyi waɗanda ke inganta ayyukan haɓakawa a cikin kwakwalwa da kuma jininta (nootropics).

1.3 Betaserc 24 MG - umarnin

Ta ƙunshi rukuni na antihistamines, wanda yake anael roba ne na matsakanci da aka saki yayin da rashin lafiyan yayi. Yana haifar da santsi mai saurin lalacewa, jijiyoyin bugun jini, rage karfin jini, fata mai ƙaiƙayi, ƙoshin zuciya, hanji da haushi da ƙwayoyin mucous.

Masu karɓar abin da ke ɗaure nau'in histamine suna nan a cikin tsakiya da na gefe na jijiya, wanda ke haifar da ciwon kai da narkewar ciki da tsananin rauni.

Betaserk yana ɗaure wa masu karɓar histamine, ciki har da cikin kunnuwan ciki, sabili da haka yana da ikon inganta yanayin ƙwayoyin jikinsa da ƙwayoyin trophic.

Sakamakon karuwar microcirculation a cikin kwarin babban jijiya, matsi na lymph a cikin labyrinth da curl an daidaita shi. Hakanan yana da ikon inganta hanyar motsa jiki tare da kwakwalwar kwakwalwa.

Yana toshe masu karɓa a cikin nuclei na mai nazarin yanayin binciken abu.

Godiya ga yin amfani da betaserk, amo da tinnitus an rage su, hare-haren dizziness suna da wuya, kuma ji ya inganta sosai, musamman a farkon cutar. Betaserc yana da sauri kuma an cire shi daga jiki ta hanta a cikin sa'o'i 24, ba tare da tarawa a ciki ba, sabili da haka ya dace da tsofaffi.

1.4 Dokokin don amfani da Betaserc 24 MG

An tsara wannan maganin ga marasa lafiya da ke fama da rashin aiki na masu binciken curl da labyrinth; yana taimaka wa irin wannan marassa lafiya da su iya shawo kan cututtukan hanji, wanda aka haɗu da tashin zuciya, amai, matashin hankali da rashin ji.

An nuna shi don fari na kunne na ciki, cututtukan Meniere ko cuta, yanayin rashin damuwa da yanayin damuwa, da ci gaban jijiyoyin bugun zuciya.

An ƙaddamar da Betaserc 24 MG don rikitaccen magani na encephalopathy wanda ke haɓaka bayan raunin, tare da atherosclerosis na tasirin maƙarƙashiya da rashin isasshen ƙwayar cuta ta vertebrobasilar.

Contraindications zuwa ga yin amfani da su za su zama asma, da kuma pepepe na ciki ko duodenum tare da ƙari. Ba za a iya amfani da shi don rashin lafiyan ga babban sinadaran aiki na ƙarin ƙwayoyi ko ƙarin abubuwan da ke ciki ba.

An contraindicated ga mata masu juna biyu a cikin farkon watanni, kuma a na biyu da na uku ana amfani da wasu lokuta, amma kawai bisa ga alamun da ke ƙarƙashin kulawar likita. Hakanan ba a ba da shawarar maganin ba yayin lactation, har ma da yara underan ƙasa da shekara goma sha takwas, saboda babu shaidar ingancinsa a wannan zamani.

Zai dace a duba cewa cin amanar ba za a bugu da sauran antihistamines ba, saboda suna rage tasirin farkon.

1.5 Gefen Hanyoyi

Marasa lafiya lura cewa daga amfani da shi, nauyi a ciki, tashin zuciya, amai da gudawa na iya bayyana, saboda wanda zai zama dole don rage kashi, kuma dole ne a yi amfani da magani kawai bayan cin abinci. Allergic halayen a cikin nau'i na fata rashes ne ƙasa da na kowa.

Tare da yin amfani da tsawan lokaci, farin ciki, bugun kirji, jan fata, fitsari da kuma raguwar hauhawar jini. Waɗannan bayyanar cututtuka sun ɓace bayan soke hanyar kulawa da maganin kwantar da hankali.

Nau'i na saki 1.6, farashi da kashi

Kamfanonin magunguna suna ba da maganin a cikin allunan 8.16 da 24 MG, a cikin fakitin su na iya zama 20, 30 ko 60 guda. Matsakaicin farashin kuzari na allunan goma cin amana 24mg - kimanin 240 rubles, 16 MG - 220, kuma farashin 8 MG - 140 rubles.

Ana ɗaukar su nan da nan bayan abinci kuma an wanke su da ruwa mai tsabta. Yawanci, ana ba da shawarar mai haƙuri 1-2 Allunan a rana na 8 MG ko guda ɗaya tare da kashi na 16 MG sau uku a rana, kuma idan ya kasance 24 MG, to, ɗayan sau biyu a rana Ana lura da cututtukan cututtuka na cututtukan kunne na ciki yawanci yana da tsawo kuma yana ɗauka daga makonni zuwa watanni.

1.8.1 Betahistine

Waɗannan sun haɗa da dukkanin magunguna waɗanda ke ɗauke da su betahistine gami da allunan suna iri daya. Wadannan kayan aikin suna da kama shaida da kuma contraindications. Side effects zai zama iri ɗaya.. Yanzun ba ya yin katsalandan da ikon tuki motoci ko yin aikin da ke da alaƙa da taro.

Hakanan yana jinyar cutar kansa da amai da gudawa, wanda ke fitowa daga mata a farkon menopause.

Gaskiya ne, marasa lafiya sun lura cewa sakamakon amfani da betagestin zai kasance ne kawai bayan makonni biyu na jiyya kuma ba koyaushe yana da kwanciyar hankali ba, kodayake tare da tsawan amfani tsananin farin ciki yana raguwa.

Amma sai farashi shiri yai yawa da cin amana kuma ya dace sosai don ɗaukar dogon lokaci da na yau da kullun.

1.8.2 Vestibo

Wani analog ɗin betaserk shine na gode, abu mai aiki na wannan kayan aiki shima betahistine. Marasa lafiya suna lura da kyakkyawan tasirin warkewar wannan magani, wanda, duk da haka, da sauri ya ɓace, kawai wajibi ne don gama amfani dashi. Wannan analog na beteserk kuma ba shi da arha - matsakaicin farashin ba shi da yawa na gode kusan 140 rubles don allunan goma.

Ana amfani da wasu rukunin magunguna don magance cututtukan kunne na ciki, alal misali, a cikin lokacin m, an wajabta masu cutar antibacterial da magungunan corticosteroid na hormonal don rage alamun kumburi, kazalika da maganin hauhawar jini na glucose ko magnesium sulfate don rage auditory jijiya edema da kuma hana matsawa a cikin kunkuntar bell canal.

1.8.3 Cavinton da vinpocetine

Wata rukunin magungunan da ke rage yawan zafin jiki a cikin marasa lafiya, da kuma inganta ji, su ne magungunan da ke shafar microcirculation na jijiyoyin kwakwalwa, da fadada abubuwan kwantar da hankali. wakilan wannan rukunin shahararrun likitoci sune cavinton da vinpocetine.

Onykot shakatawa da santsi na tsokoki na jijiyoyin bugun jini, suna ba da gudummawa ga fadadawa, rage hawan jini, ƙara yawan oxygen da glucose a cikin ƙwayoyin jijiya.

1.8.4 Piracetam, Cinnarizine, Phezam, da Cerebrolysin

Hakanan ana iya ɗaukar Nootropics analogues na betaserk - magunguna waɗanda ke haɓaka metabolism a cikin ƙwayoyin jijiya kuma suna haifar da sha'awa tare da su, kazalika da ƙarfafa bango na jijiyoyin bugun gini. Wadannan sun hada da piracetam, cinnarizine, fezam da cerebrolesin.

Ingantawa ga amfanin su ba ya faruwa nan da nan, amma tare da tsawaitawa da amfani na yau da kullun a hade tare da wasu magunguna, gami da maganin rashin ƙarfi (trental, pentoxifylline).

Karshensu suna taimakawa ga ragewar jini da kuma inganta wadatar jini ga kwakwalwa.

1.8.5 bitamin na rukuni na B

Wani rukuni na kwayoyi don lura da auditory jijiya neuritis ne Bitamin Bwanda, tare da tsawaita amfani, inganta metabolism a cikin ƙwayoyin jijiya kuma suna ba da gudummawa ga farfadowarsu, ta haka rage tinnitus da dizziness.

Dangane da al'ada, a ƙarshe, bidiyo akan wani taken da aka ba da: "Betaserk"

An kawo maka labarin: "Betaserk 24 MG - umarnin don amfani, farashi, sake dubawa, analogues" Ina fatan cewa masu karatu na wannan shafin zasu sami amfanin su san kansu da irin wannan mashahurin kwayoyi kamar betaserk, karanta umarnin sa don amfani, farashi, bita, analogues.

Amma ina so in tunatar da ku cewa wannan maganin yana da alamomin kansa, kuma musamman contraindications, sabili da haka ba shi yiwuwa a yi amfani da shi ba tare da tuntuɓar likitan ku ba.

Buformin * (Buformin *) A10BA03 Buformin

• Hypoglycemic roba da sauran jami'ai

• M11itus na ciwon sukari wanda ba shi da insulin-insulin ba
• E65-E68 Kiba da kuma sauran fannoni na rashin aiki

Kwamfutar hannu 1 ta ƙunshi buformin hydrochloride 50 MG, a cikin fakitin bolaji mai kwakwalwa guda 20,, A cikin kwali na kwali 2 fitsari.

Alamu don amfani

Ana amfani da Adebit ga marasa lafiyar marasa aikin insulin. Shan magungunan da mutane suke da lafiya ba zai haifar da rashin lafiyar hypoglycemia ba.

An wajabta magunguna Adebit don:

• nau'in ciwon sukari na 2
• kiba
• sakamakon yawan abinci mai gina jiki.

An nuna magungunan don metabolism na sukari wanda ba'a iya canzawa ba tare da haɗarin maganin hormonal.

Littafin koyarwa

Babban aikin magunguna na Adebit shine hypoglycemic.

Yana rage matakin glucose a cikin plasma, yana daidaita canjin sa yayin rana, haka kuma yana rage bukatar mara lafiyar insulin. Kayan aiki mallakar ƙungiyar biguanides ne.

Ana ɗaukar ta baki. Stimulates anaerobic glycolysis a cikin kyallen takarda na gefe. Buformin a matsayin wani ɓangare na Adebit yana ba da gudummawa ga hanawar gluconeogenesis a cikin hanta. A wannan yanayin, akwai raguwa a cikin shan glucose daga narkewa.

Magungunan yana taimakawa rage yawan ci. Buformin ya fara aiki bayan wasu 'yan sa'o'i bayan shan maganin kuma ya riƙe abubuwan ta na awa takwas.

Lokacin amfani da Adebit, hulɗarta da wasu kwayoyi ya kamata a yi la’akari da:

1. kayan rage sukari na miyagun ƙwayoyi suna raunana lokacin da aka ɗauka tare da abubuwan da aka samo na phenothiazine, hormones masu motsa jini, ƙwaƙwalwar MAO, salicylates,
2. a hankali amfani da maganin tare da diuretics. Lactic acidosis da hypovolemia na iya faruwa,
3. miyagun ƙwayoyi yana hana aikin urokinase,
4. tare da amfani tare lokaci daya tare da hana daukar ciki da corticosteroids, raguwar fahimtar juna game da tasirin magungunan biyu na faruwa.

Lokacin ɗaukar Adebit, ana inganta tasirin thrombolytics.

Yin amfani da miyagun ƙwayoyi yana haifar da kiyaye umarnin musamman:

• Yana da muhimmanci a saka idanu a kai a kai yayin motsa jiki a kullum na fitar da hankali,
• kashi na insulin ya kamata a rage hankali,
• yayin maganin ƙwayar cuta, dole ne a bi tsayayyen abinci, zaɓi abinci tare da ƙarancin glycemic index.

Haramcin shan giya yayin amfani da Adebit an haramta shi sosai. Tare da taka tsantsan, an wajabta magani don rashin haƙuri na lactose.

Fitar saki na Adebite - allunan, kunsasshen fakitin fakitin 20. Marufi - kwali na kwali. Adana miyagun ƙwayoyi dole ne ya cika wasu buƙatu: a zazzabi a ɗakuna kuma babu sama da shekaru biyar.

Umarnin don shan magungunan ya ƙunshi bayanin hanyar amfani da sashi.

Maganin farko yana daga 100 zuwa 150 MG kowace rana, wanda ya kasu kashi biyu ko sau uku, ka dauki kwamfutar hannu guda bayan cin abinci, a wanke da ruwa.

Yawan kwamfutar hannu yana ƙaruwa sau ɗaya bayan kwana 2-4. Matsakaicin abincin yau da kullun shine 300 MG na miyagun ƙwayoyi, ya kasu kashi 3-4. Don kula da sakamako, suna shan 200 MG na miyagun ƙwayoyi kowace rana, suna murƙushe shi sau huɗu.

Bidiyo masu alaƙa

Siffar magunguna don ciwon sukari na 2:

Abubuwan warkarwa na warkarwa na Adebit sun dogara da tasirin hypoglycemic. Wakilin antidi ne. A cikin marasa lafiya da nauyinsu ya wuce kima, idan aka dauki nauyin, ana rage nauyin jiki saboda karfin Adebit don rage yawan ci.

Daga cikin sakamako masu illa sune gudawa, ciwo na ciki, don haka bai kamata kuyi amfani dashi ba ga waɗanda ke fama da cututtukan gastrointestinal. An nuna magungunan don cututtukan da ba na insulin ba, da kuma rashin lafiyar da ke tattare da kiba. A kan tushen shan magani, ya kamata ku bi tsarin abinci, ku daina shan giya kuma kuyi rayuwa mai kyau.

• Yana daidaita matakan sukari na dogon lokaci
• Maido da aikin samarda insulin

Karin bayani. Ba magani bane. ->

Tasirin Aikace-aikacen:

Sanya ciki tare da abinci.

A matsayin wakili na maganin antidi, shan, farawa daga 0.1 g kowace rana (50 mg a safiya da maraice), gwargwadon canjin glucose a cikin jini da fitsari, ana iya kara yawan kashi da sannu a hankali 50 mg a rana, amma kashi na yau da kullun kada ya wuce 300 MG

Allurar kulawa yawanci yawanci 50-100 mg ne da safe da kuma 50 MG da yamma .. Idan aka hada shi da insulin, kashi na karshen ana hankali a hankali a karkashin kulawar glucose a cikin jini da fitsari.

Tare da shirye-shiryen sulfonylurea, ana wajabta glibutide a cikin lokuta idan waɗanda suka farko sun kasa rage hyperglycemia (glucose mai hauhawar jini) da glucosuria (kasancewar sukari a cikin fitsari) zuwa matakin da ake buƙata A cikin hadaddun farjin kiba, ana amfani da glibutides a 0.1 g kowace rana (sau da yawa a hade tare da anorexigenic / ci abinci mai guba / kwayoyi).

Allunan da ke aiki da allunan ana yin allunan farko (da safe), a hankali suna kara yawan zuwa allunan 4 (da safe da maraice bayan cin abinci).

Mukuwa:

Glibutide yana da haƙuri da kyau, amma ana iya rasa ci, tashin zuciya, amai, zawo (zawo), da dandano mai ƙarfe a bakin. A wani kwanan wata daga farkon magani (bayan wata daya ko sama da haka), rauni, asarar nauyi yana yiwuwa.

Abubuwan da ke tattare da sakamako yawanci suna tafiya da sauri tare da ragewa ko cire magani.

Yanayin ajiya:

Magungunan daga cikin jerin B. A cikin bushe wuri.

Buformin hydrochloride, Adebit, Butyl biguanide, Gliporal, Glibigid hydrochloride, Krebon, Silubin.

Butylbiguanide hydrochloride Farar fata mai launi na dandano mai ɗaci. Sauƙaƙe mai narkewa cikin ruwa da barasa tabletaya daga cikin kwamfutar hannu ɗayan tsawan (tsawaita) aikin buformin retard ya ƙunshi: 0.17 g na buformin tosylate, wanda yayi dace da 0.1 g na abu mai aiki (glibutide).

Shirye-shirye na irin wannan mataki:

Diaformin (Diaformin) Glucovans (Glucovance) Oltar (Oltar) Glyukofazh (Glucophage) Maninil (Maninil)

Ba ku sami bayanin da kuke buƙata ba?
Koda za'a iya samun cikakkun umarnin don magani "glibutide" za'a iya samu anan:

Ya ku likitoci!

Idan kuna da gogewa wajen tsara wannan magani ga marasa lafiyar ku - raba sakamakon (barin sharhi)! Shin wannan maganin ya taimaka wa mai haƙuri, shin akwai wasu sakamako masu illa da suka faru yayin magani? Kwarewar ku zata kasance mai ban sha'awa ga abokan aiki da kuma marasa lafiya.

Ya ku marasa lafiya!

Idan aka tsara muku wannan magani kuma kun sha hanyar magani, ku gaya mani idan yana da tasiri (ko yana taimakawa), ko akwai sakamako masu cutarwa, abubuwan da kuke so / ba ku so. Dubban mutane suna neman sake dubawa ta kan layi na magunguna daban-daban. Amma 'yan kaɗan ne suka rage su. Idan kai da kanka ba ku ba da ra'ayi ba akan wannan batun - sauran ba za su karanta ba.

Na gode da yawa!/ sitemap-index.xml

Bayanin maganin "Adebit"

Aikin Magunguna yana rage sukarin jini da sauyawarsa na yau da kullun, buƙatar insulin.

Alamu don amfani

• Nau'in sukari na II na ciwon sukari (a haɗe tare da abubuwan da ake amfani da su na sulfonylurea), kiba mai yawa, ƙwayar sukari mara ƙarfi (haɗuwa tare da insulin).

• Allunan 50m
• bakin ciki 20, akwatin (akwati) 2.

Pharmacodynamics na miyagun ƙwayoyi wakili Hypoglycemic na magani don maganin baka daga rukunin biguanides. Yana da tasiri mai motsa rai kai tsaye akan anaerobic glycolysis a cikin kyallen takarda na cikin jiki.

Yana dakatar da gluconeogenesis a cikin hanta, yana rage yawan glucose daga hancin ciki (yana hana ciwan hanji na hanji, oligo- da polysaccharides zuwa monosaccharides), yana rage ci.

Yana rage abun cikin glucagon plasma, yana kara karfin jijiyoyin jikin mutane zuwa insulin wanda ya shafi insulin ga masu karbar insulin. Aikin farawa ya kasance bayan sa'o'i 2-4, tsawon lokacin aikin shine kimanin awanni 8.

Contraindications

• Hypersensitivity, ketonuria, hyperglycemic coma, hypoglycemia, ciki, lactation. Lactic acidosis (gami da tarihi)
• hepatic da / ko gazawar koda, gazawar zuciya, gazawar numfashi, matsanancin rauni, zazzabin cizon sauro, zazzabi, cututtuka masu saurin kamuwa da cuta, albuminuria a kan asalin cututtukan cututtukan masu ciwon sukari, gangrene masu ciwon sukari.

Sakamakon sakamako: Rage abinci, tashin zuciya, amai, rauni, rashi nauyi, gastralgia, lactic acidosis, zawo, daɗin “ƙarfe” a cikin bakin, da halayen rashin lafiyan.

Sashi a ciki, 1 kwamfutar hannu. Sau 2-3 a rana bayan abinci. Matsakaicin adadin yau da kullun shine 300 mg a cikin allurai 3-4.

Yawan cututtukan cututtukan jini: hypoglycemia, hypoglycemic coma.

Harkokin hulɗa tare da wasu kwayoyi Rashin sakamako na hypoglycemic yana raunana abubuwan da suka samo asali, corticosteroids, hodar iblis mai motsa jiki, estrogens, diuretics, MAO inhibitors, salicylates.

Umarnin na musamman don amfani Wajibi ne a kula da fitar da glucose din yau da kullun a cikin fitsari, matakin glycemia. Lokacin haɗuwa da jiyya tare da buformin, ana rage kashi na insulin a hankali.

Layin adana Jerin B:: A zazzabi daki.

Tsayayyar rayuwar 60 watanni.

Abinda ke taimakawa Bilobil: umarni da sake dubawa

Maganin maganin halitta Bilobil shine tsarin psychostimulating.

Yana da nufin haɓaka aikin kwakwalwa da tsarin juyayi. An yi shi ne bisa tushen gurngoccioccic tsire-tsire daga aji na ginkgo mai riji biyu. Wannan nau'in conifers ya fito ne daga gabashin kasar Sin, amma an girma a cikin lambuna da dama na Botanical na duniya.

A kan wannan shafin za ku sami duk bayanan game da Bilobil: cikakkun umarnin don amfani da wannan magani, farashin matsakaici a cikin kantin magunguna, cikakke da ƙarancin analogues na miyagun ƙwayoyi, da sake dubawa na mutanen da suka riga sun yi amfani da Bilobil. Kuna son barin ra'ayin ku? Da fatan za a rubuta a cikin bayanan.

Formaddamar da tsari da abun da ke ciki

Chocolate masu launin ruwan kasa. Capsules suna dauke da tan foda tare da barbashi mafi duhu.

• Capaya daga cikin ƙwayar capsule ya ƙunshi azaman aiki: Dry cirewa na ganye na Ginkgo biloba - 40 MG, daidaitacce don ƙunshi 9.6 mg na Ginkgo flavone glycosides da 2.4 mg na terpene lactones (ginkgolides da bilobalides) a cikin 40 mg.
• Masu cin abinci, lactose monohydrate, sitaci masara, talc, silsila mai guba na anhydrous colloidal siliki, magnesium stearate.
• Harsashi mai kwaskwarima: gelatin, indigotine (E132), azorubine (E122), jan baƙin ƙarfe * (E172), baƙin ƙarfe baƙin ƙarfe (E 172), titanium dioxide (E 171).

Tasirin magunguna

Bilobil tsohuwar angioprotector ce ta shuka. A sakamakon gaskiyar cewa abun da ke ciki na miyagun ƙwayoyi ya hada da ginkgo biloba cirewa, wato terpene lactones da flavone glycosides, kayan aikinsa na biologically yana ƙarfafawa sosai kuma yana ƙaruwa da haɓakar jijiyoyin jini, haka kuma inganta ikon rheological jini.

Umarni Bilobil ya kuma nuna cewa maganin yana iya sarrafa tasiri gwargwadon gwargwadon ƙwayar cuta akan tsarin jijiyoyin jini, ƙara sautin jijiyoyin jiki, tsara yadda ake cike tasoshin jini da jini, kuma yana rage ƙananan hanji.

Hulɗa da ƙwayoyi

Bai kamata a rubuto Bilobil ga marasa lafiya waɗanda ke shan magungunan da ke rage ƙwaƙwalwar jini na jini (alal misali, acetylsalicylic acid da sauran magungunan anti-steroidal anti-inflammatory, kai tsaye da kuma kai tsaye kai tsaye). Irin wannan haɗuwa na iya ƙara haɗarin zubar jini saboda tsawan lokaci na coagulation.

Mun dauki wasu sharhi na mutane game da miyagun ƙwayoyi Bilobil:

1. Fatan alkhairi Bayan duban dan tayi na kwakwalwar kwakwalwa da jijiyoyin kwakwalwa, Bilobil Forte ya tsara likita, ya sha kusan shekara guda kuma ya kasa fahimtar dalilin da yasa matsin ya zama kasa da 10070, kuma hakan ya faru har kasa, kuma bugun yayi tsalle zuwa 120, taji dadi sosai, ta daina shan giya kuma a hankali komai ya zama domin ka samu sauki, har sai an warkar da daya kuma an gurgu, kana bukatar ka yi taka tsantsan da wannan maganin. Kiwan lafiya ga kowa.
2. Galina. Ta sha azumin wata daya, an fitar da ita daga osteochondrosis na mahaifa. Shugaban yana da gajimare, hangen nesa. Bai taimaka ba kwata-kwata.
3. Olga Na dauki capsules bayan bugun jini a kan shawarar likita don kawar da mummunan tasirin. "Bilobil" ya taimaka cire tinnitus da ingantaccen ƙwaƙwalwa.
4. Zina. Expensivearin tsada ba ya nufin mafi kyau! Bilobil Intens 120mg: fakitin 60 capsules yana da nauyin 970 rubles, farashin tanakan 40mg na allunan 90 na 1580, yayin da tanakan bai taimaka min ba, kuma Bilobil mai ƙarfi ya tashi. Matsalolin ƙwaƙwalwar ajiya suna buƙatar bayani a cikin nau'i mai inganci, ingantaccen magani. An bi da Bilobil tsanani kuma ba ni da matsalar ƙwaƙwalwar ajiya. Kuma kai baya zubewa, baya cutarwa. Amma babban abu shine cewa tare da bayyana a fili yana da sauƙin yin aiki da yin abubuwa yau da kullun.
5. Olya. Na sha tsawan watanni uku na bilobil tsanani. Jin dadi. Shugaban kaina ya zama mai haske, yana da sauki a yi tunani, na tuna komai kuma kar a rikita komai. Jin daɗi mara kyau kamar jin nauyi ya lalace, kuma damar fahimi ta ƙaru kamar lokacin ƙuruciya. Bilobil ya fi magunguna da yawa tare da ginkgo, wannan magani ne, ba mummunan ba ne, na halitta ne kuma mai iko, sabili da haka ina jin girma. Kafin ya sha ginkoom, amma babu wani sakamako. Bayan ginkoom, Na kewaye dukkan sharri. Kuma Bilobil magani ne. Fiye da kudin shakka.

Yawancin likitoci suna ba da tabbacin cewa ginkgo itace cirewa shine kawai magani wanda ke inganta aikin hankali a cikin marasa lafiya tsofaffi. Koyaya, binciken ya kuma nuna cewa bayan dakatar da Bilobil a cikin marasa lafiya na wannan rukuni, ana ganin sake dawo da alamomin da suka shafi shekaru.

Bayanan magungunan sune magungunan Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant da Tanakan.

Ana amfani da magungunan Bilobil sune kwayoyi kamar:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memantal
• Maruks
• Memantinol
• Memikar.

Kafin amfani da analogues, nemi likita.

Clinical da kungiyar magunguna

Magunguna wanda ke haɓaka ƙwayar jijiyoyi da na waje.

Sharuɗɗan hutu na kantin

An sake shi ba tare da takardar sayan magani ba.

Nawa ne Bilobil? Matsakaicin matsakaici a cikin kantin magunguna yana a matakin 550 rubles.

Formaddamar da tsari da abun da ke ciki

Chocolate masu launin ruwan kasa. Capsules suna dauke da tan foda tare da barbashi mafi duhu.

• Capaya daga cikin ƙwayar capsule ya ƙunshi azaman aiki: Dry cirewa na ganye na Ginkgo biloba - 40 MG, daidaitacce don ƙunshi 9.6 mg na Ginkgo flavone glycosides da 2.4 mg na terpene lactones (ginkgolides da bilobalides) a cikin 40 mg.
• Masu cin abinci, lactose monohydrate, sitaci masara, talc, silsila mai guba na anhydrous colloidal siliki, magnesium stearate.
• Harsashi mai kwaskwarima: gelatin, indigotine (E132), azorubine (E122), jan baƙin ƙarfe * (E172), baƙin ƙarfe baƙin ƙarfe (E 172), titanium dioxide (E 171).

Tasirin magunguna

Bilobil tsohuwar angioprotector ce ta shuka. A sakamakon gaskiyar cewa abun da ke ciki na miyagun ƙwayoyi ya hada da ginkgo biloba cirewa, wato terpene lactones da flavone glycosides, kayan aikinsa na biologically yana ƙarfafawa sosai kuma yana ƙaruwa da haɓakar jijiyoyin jini, haka kuma inganta ikon rheological jini.

Umarni Bilobil ya kuma nuna cewa maganin yana iya sarrafa tasiri gwargwadon gwargwadon ƙwayar cuta akan tsarin jijiyoyin jini, ƙara sautin jijiyoyin jiki, tsara yadda ake cike tasoshin jini da jini, kuma yana rage ƙananan hanji.

Alamu don amfani

An tsara Bilobil don cututtuka da yawa na tsarin juyayi, da kuma alamu daban-daban da syndromes, a cikinsu:

• Damuwa
• Tinnitus.
• Rashin damuwa
• Dyscirculatory encephalopathy, musamman tare da rashin fahimta.
• Dizziness, da farko lalacewa ta hanyar jijiyoyin bugun gini.
• Rage yawan kulawa.

Hakanan za'a iya amfani da Bilobil a cikin hadadden jiyya a gaban rikicewar jijiyoyin jini a cikin tasoshin ƙananan ƙarshen (aikin angiosurgery).

Contraindications

Yawancin lokaci ana amincewa da miyagun ƙwayoyi sosai ta hanyar marasa lafiya, duk da haka, a cikin lokuta daban, an lura da ci gaban irin wannan sakamako masu illa:

• Daga tsarin juyayi na tsakiya: ciwon kai, ƙaruwar fushi.
• Allergic halayen: fatar fata, itching, urticaria, Quincke ta edema.
• Daga tsarin narkewa: tashin zuciya, amai, matsi mai rauni.

Tare da haɓaka halayen rashin lafiyan halayen, cire magani ya zama dole.

Yawancin lokuta ana lura da ci gaban sakamako yayin shan miyagun ƙwayoyi Bilobil Intens, da kuma a cikin tsofaffi marasa lafiya da babban allurai na miyagun ƙwayoyi.

Haihuwa da lactation

Saboda ƙarancin isasshen bayanan asibiti, ba a ba da shawarar Bilobil don amfani da shi lokacin daukar ciki da lokacin shayarwa ba.

Umarnin don amfani

Umarni don amfani yana nuna cewa Bilobil an ɗauke shi da baka. Ya kamata a haɗu da kicin ɗin duka tare da ɗan karamin ruwa, ba tare da la'akari da abincin ba.

1. Encephalopathy na dyscirculatory na etiologies daban-daban: 1-2 iyakoki. Sau 3 / rana
2. Rashin hankali na hankali (rashin jin daɗi, tinnitus, hypoacusia), gurguwar ƙwaƙwalwar ƙwaƙwalwa, ƙwaƙwalwar ƙwayar cuta: 1 caps. Sau 3 / rana
3. Hargitsi da kewaye jini kewaye da microcirculation (gami da ƙananan ƙwaƙwalwar arteriopathy), raunin Raynaud: 1 caps. Sau 3 / rana

Alamar farko na haɓakawa ana bayyana ta bayan wata 1. Aikin magani shine aƙalla watanni 3 (musamman ga tsofaffi marasa lafiya). Na biyu hanya mai yiwuwa ne bayan tattaunawa da likita.

Side effects

Shan miyagun ƙwayoyi na iya tayar da sakamako masu biyo baya: amai, tashin zuciya, amai, ciwon kai, kumburi, ƙonewar fata, ƙaiƙayi, ji mai gani da hangen nesa, raunin ƙwayar jijiyoyi, ƙonewa, da kuma rashin bacci.

A wasu halaye, bilobil na iya haifar da zub da jini a cikin kwakwalwa.Wannan ya shafi musamman ga yanayi lokacin da aka karɓi magani tare da wakilai masu ɗaukar jinin. Gabaɗaya, ana lura da sakamako masu illa na ɗan lokaci kaɗan kuma na ɗan lokaci ne. Koyaya, idan sun faru, ya kamata ka tuntuɓi likita nan da nan.

Yawan abin sama da ya kamata

Idan adadin ya wuce, sakamakon haɓakar halayen na iya inganta. Kulawar ta gargajiya ce, dangane da alamomin.

Umarni na musamman

Sakamakon warkewa na miyagun ƙwayoyi yana faruwa bayan kimanin wata guda da shan maganin. Idan a cikin lokacin da ake amfani da maganin ƙwayar cuta akwai lalacewa kwatsam, raunin ji, tinnitus ko danshi ya bayyana, dole ne ka dakatar da shan maganin kuma cikin gaggawa neman shawarar likita.

Ba'a ba da shawarar sanya Bilobil ga marasa lafiya waɗanda ke fama da cutar galactose ko glucose malabsorption syndrome, na nakasar galactosemia ko rashi na lactase, saboda lactose wani ɓangare ne na shi.

Hulɗa da ƙwayoyi

Bai kamata a rubuto Bilobil ga marasa lafiya waɗanda ke shan magungunan da ke rage ƙwaƙwalwar jini na jini (alal misali, acetylsalicylic acid da sauran magungunan anti-steroidal anti-inflammatory, kai tsaye da kuma kai tsaye kai tsaye). Irin wannan haɗuwa na iya ƙara haɗarin zubar jini saboda tsawan lokaci na coagulation.

Mun dauki wasu sharhi na mutane game da miyagun ƙwayoyi Bilobil:

1. Fatan alkhairi Bayan duban dan tayi na kwakwalwar kwakwalwa da jijiyoyin kwakwalwa, Bilobil Forte ya tsara likita, ya sha kusan shekara guda kuma ya kasa fahimtar dalilin da yasa matsin ya zama kasa da 10070, kuma hakan ya faru har kasa, kuma bugun yayi tsalle zuwa 120, taji dadi sosai, ta daina shan giya kuma a hankali komai ya zama domin ka samu sauki, har sai an warkar da daya kuma an gurgu, kana bukatar ka yi taka tsantsan da wannan maganin. Kiwan lafiya ga kowa.
2. Galina. Ta sha azumin wata daya, an fitar da ita daga osteochondrosis na mahaifa. Shugaban yana da gajimare, hangen nesa. Bai taimaka ba kwata-kwata.
3. Olga Na dauki capsules bayan bugun jini a kan shawarar likita don kawar da mummunan tasirin. "Bilobil" ya taimaka cire tinnitus da ingantaccen ƙwaƙwalwa.
4. Zina. Expensivearin tsada ba ya nufin mafi kyau! Bilobil Intens 120mg: fakitin 60 capsules yana da nauyin 970 rubles, farashin tanakan 40mg na allunan 90 na 1580, yayin da tanakan bai taimaka min ba, kuma Bilobil mai ƙarfi ya tashi. Matsalolin ƙwaƙwalwar ajiya suna buƙatar bayani a cikin nau'i mai inganci, ingantaccen magani. An bi da Bilobil tsanani kuma ba ni da matsalar ƙwaƙwalwar ajiya. Kuma kai baya zubewa, baya cutarwa. Amma babban abu shine cewa tare da bayyana a fili yana da sauƙin yin aiki da yin abubuwa yau da kullun.
5. Olya. Na sha tsawan watanni uku na bilobil tsanani. Jin dadi. Shugaban kaina ya zama mai haske, yana da sauki a yi tunani, na tuna komai kuma kar a rikita komai. Jin daɗi mara kyau kamar jin nauyi ya lalace, kuma damar fahimi ta ƙaru kamar lokacin ƙuruciya. Bilobil ya fi magunguna da yawa tare da ginkgo, wannan magani ne, ba mummunan ba ne, na halitta ne kuma mai iko, sabili da haka ina jin girma. Kafin ya sha ginkoom, amma babu wani sakamako. Bayan ginkoom, Na kewaye dukkan sharri. Kuma Bilobil magani ne. Fiye da kudin shakka.

Yawancin likitoci suna ba da tabbacin cewa ginkgo itace cirewa shine kawai magani wanda ke inganta aikin hankali a cikin marasa lafiya tsofaffi. Koyaya, binciken ya kuma nuna cewa bayan dakatar da Bilobil a cikin marasa lafiya na wannan rukuni, ana ganin sake dawo da alamomin da suka shafi shekaru.

Bayanan magungunan sune magungunan Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant da Tanakan.

Ana amfani da magungunan Bilobil sune kwayoyi kamar:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memantal
• Maruks
• Memantinol
• Memikar.

Kafin amfani da analogues, nemi likita.

Yanayin ajiya da rayuwar shiryayye

Magungunan sun dace don amfani na shekaru uku. Kada ku bayar da dama ga yara, kariya daga haske. Zafin 200C.

Clinical da kungiyar magunguna

Mai hana H + -K + -ATPase. Magungunan ƙwayar cuta

Tsarin saki, abun da aka shirya da marufi

◊ Shigar ciki capsules gelatin mai wuya, girman No. 3, tare da farin jiki da shuɗi mai shudi, abubuwan da ke cikin capsules suna da murfin huda daga kusan fararen fari zuwa fararen mai laushi mai laushi ko shuɗi.

* rabeprazole, abu pellet 8.5% - 118 mg.

Mahalarta: sukarin sukari (sucrose - 99.83%, povidone - 0.17%) - 71.46 mg, sodium carbonate - 1.66 mg, talc - 1.77 mg, titanium dioxide - 0.83 mg, hypromellose - 14.75 mg.

Fitowa na kwasfa pellet: hypromellose phthalate - 15.94 mg, cetyl barasa - 1.59 mg.
Abinda ke ciki na kwalliyar wuya gelatin A'a 3: jikin kwalliya - titanium dioxide - 2%, gelatin - har zuwa 100%, kwalin capsule - titanium dioxide - 2%, fenti mai launin shuɗi - 0.0176%, ruwan ɗimbin lu'u-lu'u - 0.0051%, gelatin - har zuwa 100%.

5 inji mai kwakwalwa. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. 7 inji mai kwakwalwa. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali.

Guda 14. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali.

30 inji mai kwakwalwa - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali.

Pharmacokinetics

Tsotsa da rarrabawa

Rabeprazole yana ɗaukar hanzari daga hanji, Cmax a cikin plasma jini an kai shi kimanin sa'o'i 3.5 bayan gudanarwa a kashi 20 na MG. Canje-canje a cikin Cmax a cikin jini, ƙimar AUC na rabeprazole sune layi a cikin kewayon allurai daga 10 zuwa 40 MG.

Cikakken bayanin bioavailability bayan sarrafa bakin a kashi 20 na MG (idan aka kwatanta da iv) kusan 52%. Bugu da kari, bioavailability bai canza tare da allurai na rabeprazole. Babu lokacin shan miyagun ƙwayoyi a lokacin rana, ko kuma gudanar da maganin hana daukar ciki na magance ɗaukar rabeprazole.

Shan miyagun ƙwayoyi tare da abinci mai ƙiba yana rage jinkirin rabeprazole na tsawon sa'o'i 4 ko fiye, duk da haka, babu Cmax ko yanayin canzawar canji.

Ulla rabeprazole ga ƙwayoyin plasma kusan kashi 97%.

Metabolism da excretion

Babban metabolite shine thioether (M1). Itewaƙwalwar metabolite mai aiki kawai shine desmethyl (M3), duk da haka, an ƙaddara shi a cikin ƙananan taro a cikin mahalarta binciken guda ɗaya bayan ɗaukar rabeprazole a kashi 80 MG.

Bayan kashi ɗaya na sodium 14C-wanda aka yiwa alama mai rabeprazole a kashi 20 na MG, ba a sami magungunan da ba su canza ba a cikin fitsari.

Kusan 90% na rabeprazole an keɓance ta ta hanyar kodan galibi a cikin nau'i biyu na metabolites: conjugate na mercapturic acid (M5) da acid acid na carbon (M6), da kuma a cikin nau'ikan metabolites guda biyu waɗanda ba a san su ba yayin nazarin toxicological. Ragowar sbeum rabeprazole da aka dauka yana kece ta cikin hanji.

Jimlar kawar da kashi 99.8%. Waɗannan bayanan suna nuna ɗan ƙaramin kewayon rabeprazole sodium metabolites tare da bile.

A cikin masu sa kai lafiya, plasma T1 / 2 kusan awa 1 ne (kama daga 0.7 zuwa awa 1.5), jimlar ɗaukar nauyin 3.8 ml / min / kg.

Pharmacokinetics a cikin rukunin masu haƙuri na musamman

A cikin marasa lafiya da lalacewar hanta na wucin gadi, AUC an ninka sau biyu idan aka kwatanta da masu ba da agaji na lafiya, wanda ke nuna raguwar metabolism yayin "wucewar farko", kuma T1 / 2 daga plasma jini yana ƙaruwa sau 2-3.

A cikin marasa lafiya da tsayayyen ƙarshen-matakin renal gazawar waɗanda suke buƙatar tabbatarwa hemodialysis (CC

• Capaya daga cikin kwandon Bilobil ya ƙunshi nauyin 40 na ganyayyaki daga ganyen bishiya ginkgo biyu mai haushi.
• Capaya daga cikin kwandon Bilobil Forte ya haɗa da nauyin 80 na cirewa daga ganyen bishiya ginkgo biyu mai haushi.

100 MG na cirewa ya hada da 19.2 MG ginkgo glycosides nau'in flavone da 4.

8 MG terpene lactones nau'in (bilobalides da ginkgolides).

Substancesarin abubuwa: colloidal silicon oxide, sitaci masara, lactose monohydrate, magnesium stearate, talc.

Harshen Shell: launin fenti mai farin ƙarfe, titanium dioxide, azorubine, baƙin ƙarfe baƙin ƙarfe, gelatin.

Pharmacodynamics

Phytopreching, al'ada metabolism a cikin sel rheological alamomi jini da turare nama.

Yana haɓaka keɓaɓɓiyar ƙwayar cuta kuma yana samar da kwakwalwa glucose da oxygenyana hana tarawa ƙwayoyin jiniyana hana kunnawa countlet plate.

Yana da tasiri mai dogaro da iko akan tsarin jijiyoyin jiki, yana kunna samar KADA, yana fadada lumen arterioles, yana kara sautin jijiyoyi, ta haka ne yake cike gurbin jijiyoyin jini. Weakens permeability na jirgin ruwa bango.

Samun mallaka maganin ƙwayar cuta aiki (yana karfafa membranes na sel jini da platelet, yana tasiri biosynthesis) prostaglandinsyana raunana sakamako platelet-activation factor) Yana hana peroxidation na fats na membranes na tantanin halitta da samuwar tsattsauran ra'ayi.

Normalizes metabolism ƙwaƙwalwar ƙwaƙwalwa (kamar dopamine, norepinephrine da karafarini) Hakanan yana da antihypoxic aiki, yana ƙarfafa metabolism, yana haɓaka tarawa macroergsYana hanzarta zubar da abubuwa glucose da oxygenyana tsara hanyoyin shiga tsakani a cikin kwakwalwa.

Side effects

Rage ci, tashin zuciya, ciwon ciki, sako-sako da sako, ƙarfe ɗanɗano a bakin, lactic acidosis.

Haɗa kai

Sakamakon yana rage ta hanyar corticosteroids.

Sashi da gudanarwa

A ciki, tebur 1 2 sau 3 yau da kullun bayan abinci. Matsakaicin adadin kullun na 300 MG a cikin 3 4 allurai.

Kariya da aminci

Ya kamata a tsara takaddara a hade tare da diuretics (musamman tare da abubuwan da ke cikin thiazide).

Saboda haɗarin lactic acidosis, ya kamata a yi gwajin jini kowace wata shida, kuma ya kamata a sa ido a kan aikin hanta da koda. Kafin tiyata, sauyawa zuwa ilimin insulin ya zama dole.

A lokacin jiyya, ba za ku iya shan barasa ba, saboda A wasu halaye, rashin haƙuri na iya faruwa.

Yanayin ajiya na miyagun ƙwayoyi Adebit

A zazzabi a daki.

Ayi nesa da isar yara.

Shelf rayuwar miyagun ƙwayoyi Adebit

Daidaita maganar kungiyoyin nosological

Umarnin Glibutide, sake dubawa, farashi, bayanin

Suna:

Aikin magunguna:

Ya kasance na roba na roba na hypoglycemic (antidiabetic) magunguna (shirye-shiryen da ke rage sukarin jini) na ƙungiyar biguanide Mafi girman tasirin hypoglycemic (saukar da sukari na jini) yana faruwa awanni 4-5 bayan shan magani.

Glibutide, kamar sauran biguanides, yana nufin magungunan antidi da na baka wanda ke haifar da raguwa mai yawa a jikin mutum a cikin masu fama da cutar sikari.

Wadannan kwayoyi suna rage yawan ci, inganta anaerobic glycolysis (samar da makamashi a cikin kwayar halitta ba tare da shigawar oxygen ba), rage shayewar glucose daga hanji, suna da maganin rigakafi (rage karfin mai) da tasirin fibinolytic (warwatsewar jijiyoyin jini).

Alamu don amfani:

Ana amfani dashi don magance nau'in ciwon sukari na II mellitus (insulin-mai zaman kanta) a cikin manya.

A hade tare da insulin, ana amfani dashi don nau'ikan insulin-resistant na ciwon sukari (ciwon sukari, tsayayya wa magani tare da shirye-shiryen insulin), kazalika da juriya (juriya) ga magungunan antidiabetic na sulfonylurea, don siffofin mai laushi mai sauƙi, tare da kiba, kuma a cikin marasa lafiya suna karɓar maganin insulin a cikin sukari mai laushi ciwon sukari (ciwon sukari mellitus, wanda aka san shi da canji mai sauri a cikin sukarin jini).

Tasirin Aikace-aikacen:

Sanya ciki tare da abinci.

A matsayin wakili na maganin antidi, shan, farawa daga 0.1 g kowace rana (50 mg a safiya da maraice), gwargwadon canjin glucose a cikin jini da fitsari, ana iya kara yawan kashi da sannu a hankali 50 mg a rana, amma kashi na yau da kullun kada ya wuce 300 MG

Allurar kulawa yawanci yawanci 50-100 mg ne da safe da kuma 50 MG da yamma .. Idan aka hada shi da insulin, kashi na karshen ana hankali a hankali a karkashin kulawar glucose a cikin jini da fitsari.

Tare da shirye-shiryen sulfonylurea, ana wajabta glibutide a cikin lokuta idan waɗanda suka farko sun kasa rage hyperglycemia (glucose mai hauhawar jini) da glucosuria (kasancewar sukari a cikin fitsari) zuwa matakin da ake buƙata A cikin hadaddun farjin kiba, ana amfani da glibutides a 0.1 g kowace rana (sau da yawa a hade tare da anorexigenic / ci abinci mai guba / kwayoyi).

Allunan da ke aiki da allunan ana yin allunan farko (da safe), a hankali suna kara yawan zuwa allunan 4 (da safe da maraice bayan cin abinci).

Mukuwa:

Glibutide yana da haƙuri da kyau, amma ana iya rasa ci, tashin zuciya, amai, zawo (zawo), da dandano mai ƙarfe a bakin. A wani kwanan wata daga farkon magani (bayan wata daya ko sama da haka), rauni, asarar nauyi yana yiwuwa.

Abubuwan da ke tattare da sakamako yawanci suna tafiya da sauri tare da ragewa ko cire magani.

Yarjejeniyar:

Contraindications zuwa ga yin amfani da glibutide sune: cikakkun alamomi don amfani da insulin, rashi a cikin jikin endogenous (wanda aka kirkira a cikin jikin mutum) ko an sarrafa shi (insulin cikin waje), kwayar cutar (asarar hankali, bayyanar da cikakkiyar rashi na halayen jiki na motsawar waje), acidosis (acidation), cututtuka masu kamuwa da cuta, albuminuria (furotin a cikin fitsari) saboda cutar sankarau (lalacewar jijiyoyin jini da ƙoda a cikin ƙwayar mellitus), lalacewar hanta, angiopathy masu ciwon sukari (cin zarafi sautin jini na jini wanda aka haɗu da sukari mai jini) tare da yuwuwar haɓaka tsarin kumburi, ƙwayar cuta daga ɗayan ciki, ciki.Ya kamata a ɗauka a zuciya cewa wasu marasa lafiya na iya haɓaka ketosis tare da glibutide (acidation saboda yawan abin da ke jikin ketone a cikin jini - samfuran tsaka-tsaki metabolism) tare da raguwa da alkalinity na ajiyar jini (aikin tsarin mai saukar da jini, wanda ke hana canji a cikin pH).

Game da ketosis, an soke maganin. Lokacin yin jiyya tare da glibutide, musamman a farkon lokacin, yana da buqatar bincika fitsari don abubuwan acetone a ciki. A nan gaba, ana aiwatar da ƙuduri na jikin ketone (samfuran matsakaiciyar matsakaici) kusan lokaci 1 a mako.

Tsarin sakin samfuri:

Allunan 0.05 g a cikin kunshin 50 guda. Allunan aiki na buformin retard.

Yanayin ajiya:

Magungunan daga cikin jerin B. A cikin bushe wuri.

Buformin hydrochloride, Adebit, Butyl biguanide, Gliporal, Glibigid hydrochloride, Krebon, Silubin.

Butylbiguanide hydrochloride Farar fata mai launi na dandano mai ɗaci.Sauƙaƙe mai narkewa cikin ruwa da barasa tabletaya daga cikin kwamfutar hannu ɗayan tsawan (tsawaita) aikin buformin retard ya ƙunshi: 0.17 g na buformin tosylate, wanda yayi dace da 0.1 g na abu mai aiki (glibutide).

Shirye-shirye na irin wannan mataki:

Diaformin (Diaformin) Glucovans (Glucovance) Oltar (Oltar) Glyukofazh (Glucophage) Maninil (Maninil)

Ba ku sami bayanin da kuke buƙata ba?
Koda za'a iya samun cikakkun umarnin don magani "glibutide" za'a iya samu anan:

Ya ku likitoci!

Idan kuna da gogewa wajen tsara wannan magani ga marasa lafiyar ku - raba sakamakon (barin sharhi)! Shin wannan maganin ya taimaka wa mai haƙuri, shin akwai wasu sakamako masu illa da suka faru yayin magani? Kwarewar ku zata kasance mai ban sha'awa ga abokan aiki da kuma marasa lafiya.

Ya ku marasa lafiya!

Idan aka tsara muku wannan magani kuma kun sha hanyar magani, ku gaya mani idan yana da tasiri (ko yana taimakawa), ko akwai sakamako masu cutarwa, abubuwan da kuke so / ba ku so. Dubban mutane suna neman sake dubawa ta kan layi na magunguna daban-daban. Amma 'yan kaɗan ne suka rage su. Idan kai da kanka ba ku ba da ra'ayi ba akan wannan batun - sauran ba za su karanta ba.

Na gode da yawa!/ sitemap-index.xml

Bayanin maganin "Adebit"

Aikin Magunguna yana rage sukarin jini da sauyawarsa na yau da kullun, buƙatar insulin.

Alamu don amfani

• Nau'in sukari na II na ciwon sukari (a haɗe tare da abubuwan da ake amfani da su na sulfonylurea), kiba mai yawa, ƙwayar sukari mara ƙarfi (haɗuwa tare da insulin).

• Allunan 50m
• bakin ciki 20, akwatin (akwati) 2.

Pharmacodynamics na miyagun ƙwayoyi wakili Hypoglycemic na magani don maganin baka daga rukunin biguanides. Yana da tasiri mai motsa rai kai tsaye akan anaerobic glycolysis a cikin kyallen takarda na cikin jiki.

Yana dakatar da gluconeogenesis a cikin hanta, yana rage yawan glucose daga hancin ciki (yana hana ciwan hanji na hanji, oligo- da polysaccharides zuwa monosaccharides), yana rage ci.

Yana rage abun cikin glucagon plasma, yana kara karfin jijiyoyin jikin mutane zuwa insulin wanda ya shafi insulin ga masu karbar insulin. Aikin farawa ya kasance bayan sa'o'i 2-4, tsawon lokacin aikin shine kimanin awanni 8.

Contraindications

• Hypersensitivity, ketonuria, hyperglycemic coma, hypoglycemia, ciki, lactation. Lactic acidosis (gami da tarihi)
• hepatic da / ko gazawar koda, gazawar zuciya, gazawar numfashi, matsanancin rauni, zazzabin cizon sauro, zazzabi, cututtuka masu saurin kamuwa da cuta, albuminuria a kan asalin cututtukan cututtukan masu ciwon sukari, gangrene masu ciwon sukari.

Sakamakon sakamako: Rage abinci, tashin zuciya, amai, rauni, rashi nauyi, gastralgia, lactic acidosis, zawo, daɗin “ƙarfe” a cikin bakin, da halayen rashin lafiyan.

Sashi a ciki, 1 kwamfutar hannu. Sau 2-3 a rana bayan abinci. Matsakaicin adadin yau da kullun shine 300 mg a cikin allurai 3-4.

Yawan cututtukan cututtukan jini: hypoglycemia, hypoglycemic coma.

Harkokin hulɗa tare da wasu kwayoyi Rashin sakamako na hypoglycemic yana raunana abubuwan da suka samo asali, corticosteroids, hodar iblis mai motsa jiki, estrogens, diuretics, MAO inhibitors, salicylates.

Umarnin na musamman don amfani Wajibi ne a kula da fitar da glucose din yau da kullun a cikin fitsari, matakin glycemia. Lokacin haɗuwa da jiyya tare da buformin, ana rage kashi na insulin a hankali.

Layin adana Jerin B:: A zazzabi daki.

Tsayayyar rayuwar 60 watanni.

Azuzuwan cutar

Mellitus na rashin insulin-da ke fama da cutar kansa

Kasuwanci na ATX (ATC)

Maganin narkewa da narkewar abinci

Aikin magunguna

Bayanin bayanin sakamako na hypoglycemic yana nufin rage matakan glucose na jini. Hanyar aikin ta dogara ne da ɗaukar nauyin insulin ga masu karɓar sa, ta hakan yana shafar metabolism na glucose.

Sakamakon haka, ana rage matakin glucose a cikin jini saboda karuwa a cikin amfanin shi a cikin kasusuwa na musamman, musamman a cikin kasusuwa da kasusuwa na tso adi, da kuma hana samuwar glucose a cikin hanta.

Baya ga tasirin insulin kai tsaye, hanyar aiwatar da aiki yana da alaƙa da haɓakar ƙwayar ƙwayar cuta ta ƙwayoyin cuta, tare da haɗuwa da haɓakar sakin insulin, daga ɗaukar takamaiman masu karɓa (hade da tashoshin potassium na ATP-dogara akan tashoshin).

Hakanan, hanyar aiwatar da aiki na iya kasancewa yana da alaƙa da hana gluconeogenesis a cikin hanta (gami da glycogenolysis) da haɓaka amfani da glucose ta hanyar jijiyoyin jiki, hana insulin shigowa da haɓaka ta ɗaure wa masu karɓar insulin (wannan yana ƙara haɓaka glucose da metabolism).

Ofaya daga cikin hanyoyin aikin shine rage ƙarfin juriya a cikin kyallen mahaifa da hanta. Abun hana rushewar kwayar poly- da oligosaccharides yana yiwuwa, wanda ya rage samuwar jini da hanji a cikin hanji, don haka hana haɓakar tasirin cuta mai zuwa bayan jini. Ana amfani da magungunan hypoglycemic don magance ciwon sukari.

Kungiyar magunguna

Hypoglycemic roba da sauran jami'ai

Abubuwa masu aiki

Bayanin White farin lu'ulu'u na ɗanɗano mai ɗaci. Sauƙi mai narkewa cikin ruwa da barasa.

Bayanan da aka bayar don dalilai na bayanai ne kawai.
Kafin amfani, da fatan za a nemi shawara tare da gwani.

Abinda ke taimakawa Bilobil: umarni da sake dubawa

Maganin maganin halitta Bilobil shine tsarin psychostimulating.

Yana da nufin haɓaka aikin kwakwalwa da tsarin juyayi. An yi shi ne bisa tushen gurngoccioccic tsire-tsire daga aji na ginkgo mai riji biyu. Wannan nau'in conifers ya fito ne daga gabashin kasar Sin, amma an girma a cikin lambuna da dama na Botanical na duniya.

A kan wannan shafin za ku sami duk bayanan game da Bilobil: cikakkun umarnin don amfani da wannan magani, farashin matsakaici a cikin kantin magunguna, cikakke da ƙarancin analogues na miyagun ƙwayoyi, da sake dubawa na mutanen da suka riga sun yi amfani da Bilobil. Kuna son barin ra'ayin ku? Da fatan za a rubuta a cikin bayanan.

Clinical da kungiyar magunguna

Magunguna wanda ke haɓaka ƙwayar jijiyoyi da na waje.

Sharuɗɗan hutu na kantin

An sake shi ba tare da takardar sayan magani ba.

Nawa ne Bilobil? Matsakaicin matsakaici a cikin kantin magunguna yana a matakin 550 rubles.

Formaddamar da tsari da abun da ke ciki

Chocolate masu launin ruwan kasa. Capsules suna dauke da tan foda tare da barbashi mafi duhu.

• Capaya daga cikin ƙwayar capsule ya ƙunshi azaman aiki: Dry cirewa na ganye na Ginkgo biloba - 40 MG, daidaitacce don ƙunshi 9.6 mg na Ginkgo flavone glycosides da 2.4 mg na terpene lactones (ginkgolides da bilobalides) a cikin 40 mg.
• Masu cin abinci, lactose monohydrate, sitaci masara, talc, silsila mai guba na anhydrous colloidal siliki, magnesium stearate.
• Harsashi mai kwaskwarima: gelatin, indigotine (E132), azorubine (E122), jan baƙin ƙarfe * (E172), baƙin ƙarfe baƙin ƙarfe (E 172), titanium dioxide (E 171).

Tasirin magunguna

Bilobil tsohuwar angioprotector ce ta shuka. A sakamakon gaskiyar cewa abun da ke ciki na miyagun ƙwayoyi ya hada da ginkgo biloba cirewa, wato terpene lactones da flavone glycosides, kayan aikinsa na biologically yana ƙarfafawa sosai kuma yana ƙaruwa da haɓakar jijiyoyin jini, haka kuma inganta ikon rheological jini.

Umarni Bilobil ya kuma nuna cewa maganin yana iya sarrafa tasiri gwargwadon gwargwadon ƙwayar cuta akan tsarin jijiyoyin jini, ƙara sautin jijiyoyin jiki, tsara yadda ake cike tasoshin jini da jini, kuma yana rage ƙananan hanji.

Alamu don amfani

An tsara Bilobil don cututtuka da yawa na tsarin juyayi, da kuma alamu daban-daban da syndromes, a cikinsu:

• Damuwa
• Tinnitus.
• Rashin damuwa
• Dyscirculatory encephalopathy, musamman tare da rashin fahimta.
• Dizziness, da farko lalacewa ta hanyar jijiyoyin bugun gini.
• Rage yawan kulawa.

Hakanan za'a iya amfani da Bilobil a cikin hadadden jiyya a gaban rikicewar jijiyoyin jini a cikin tasoshin ƙananan ƙarshen (aikin angiosurgery).

Contraindications

Yawancin lokaci ana amincewa da miyagun ƙwayoyi sosai ta hanyar marasa lafiya, duk da haka, a cikin lokuta daban, an lura da ci gaban irin wannan sakamako masu illa:

• Daga tsarin juyayi na tsakiya: ciwon kai, ƙaruwar fushi.
• Allergic halayen: fatar fata, itching, urticaria, Quincke ta edema.
• Daga tsarin narkewa: tashin zuciya, amai, matsi mai rauni.

Tare da haɓaka halayen rashin lafiyan halayen, cire magani ya zama dole.

Yawancin lokuta ana lura da ci gaban sakamako yayin shan miyagun ƙwayoyi Bilobil Intens, da kuma a cikin tsofaffi marasa lafiya da babban allurai na miyagun ƙwayoyi.

Haihuwa da lactation

Saboda ƙarancin isasshen bayanan asibiti, ba a ba da shawarar Bilobil don amfani da shi lokacin daukar ciki da lokacin shayarwa ba.

Umarnin don amfani

Umarni don amfani yana nuna cewa Bilobil an ɗauke shi da baka. Ya kamata a haɗu da kicin ɗin duka tare da ɗan karamin ruwa, ba tare da la'akari da abincin ba.

1. Encephalopathy na dyscirculatory na etiologies daban-daban: 1-2 iyakoki. Sau 3 / rana
2. Rashin hankali na hankali (rashin jin daɗi, tinnitus, hypoacusia), gurguwar ƙwaƙwalwar ƙwaƙwalwa, ƙwaƙwalwar ƙwayar cuta: 1 caps. Sau 3 / rana
3. Hargitsi da kewaye jini kewaye da microcirculation (gami da ƙananan ƙwaƙwalwar arteriopathy), raunin Raynaud: 1 caps. Sau 3 / rana

Alamar farko na haɓakawa ana bayyana ta bayan wata 1. Aikin magani shine aƙalla watanni 3 (musamman ga tsofaffi marasa lafiya). Na biyu hanya mai yiwuwa ne bayan tattaunawa da likita.

Side effects

Shan miyagun ƙwayoyi na iya tayar da sakamako masu biyo baya: amai, tashin zuciya, amai, ciwon kai, kumburi, ƙonewar fata, ƙaiƙayi, ji mai gani da hangen nesa, raunin ƙwayar jijiyoyi, ƙonewa, da kuma rashin bacci.

A wasu halaye, bilobil na iya haifar da zub da jini a cikin kwakwalwa. Wannan ya shafi musamman ga yanayi lokacin da aka karɓi magani tare da wakilai masu ɗaukar jinin. Gabaɗaya, ana lura da sakamako masu illa na ɗan lokaci kaɗan kuma na ɗan lokaci ne. Koyaya, idan sun faru, ya kamata ka tuntuɓi likita nan da nan.

Yawan abin sama da ya kamata

Idan adadin ya wuce, sakamakon haɓakar halayen na iya inganta. Kulawar ta gargajiya ce, dangane da alamomin.

Umarni na musamman

Sakamakon warkewa na miyagun ƙwayoyi yana faruwa bayan kimanin wata guda da shan maganin. Idan a cikin lokacin da ake amfani da maganin ƙwayar cuta akwai lalacewa kwatsam, raunin ji, tinnitus ko danshi ya bayyana, dole ne ka dakatar da shan maganin kuma cikin gaggawa neman shawarar likita.

Ba'a ba da shawarar sanya Bilobil ga marasa lafiya waɗanda ke fama da cutar galactose ko glucose malabsorption syndrome, na nakasar galactosemia ko rashi na lactase, saboda lactose wani ɓangare ne na shi.

Hulɗa da ƙwayoyi

Bai kamata a rubuto Bilobil ga marasa lafiya waɗanda ke shan magungunan da ke rage ƙwaƙwalwar jini na jini (alal misali, acetylsalicylic acid da sauran magungunan anti-steroidal anti-inflammatory, kai tsaye da kuma kai tsaye kai tsaye). Irin wannan haɗuwa na iya ƙara haɗarin zubar jini saboda tsawan lokaci na coagulation.

Mun dauki wasu sharhi na mutane game da miyagun ƙwayoyi Bilobil:

1. Fatan alkhairi Bayan duban dan tayi na kwakwalwar kwakwalwa da jijiyoyin kwakwalwa, Bilobil Forte ya tsara likita, ya sha kusan shekara guda kuma ya kasa fahimtar dalilin da yasa matsin ya zama kasa da 10070, kuma hakan ya faru har kasa, kuma bugun yayi tsalle zuwa 120, taji dadi sosai, ta daina shan giya kuma a hankali komai ya zama domin ka samu sauki, har sai an warkar da daya kuma an gurgu, kana bukatar ka yi taka tsantsan da wannan maganin. Kiwan lafiya ga kowa.
2. Galina. Ta sha azumin wata daya, an fitar da ita daga osteochondrosis na mahaifa. Shugaban yana da gajimare, hangen nesa.Bai taimaka ba kwata-kwata.
3. Olga Na dauki capsules bayan bugun jini a kan shawarar likita don kawar da mummunan tasirin. "Bilobil" ya taimaka cire tinnitus da ingantaccen ƙwaƙwalwa.
4. Zina. Expensivearin tsada ba ya nufin mafi kyau! Bilobil Intens 120mg: fakitin 60 capsules yana da nauyin 970 rubles, farashin tanakan 40mg na allunan 90 na 1580, yayin da tanakan bai taimaka min ba, kuma Bilobil mai ƙarfi ya tashi. Matsalolin ƙwaƙwalwar ajiya suna buƙatar bayani a cikin nau'i mai inganci, ingantaccen magani. An bi da Bilobil tsanani kuma ba ni da matsalar ƙwaƙwalwar ajiya. Kuma kai baya zubewa, baya cutarwa. Amma babban abu shine cewa tare da bayyana a fili yana da sauƙin yin aiki da yin abubuwa yau da kullun.
5. Olya. Na sha tsawan watanni uku na bilobil tsanani. Jin dadi. Shugaban kaina ya zama mai haske, yana da sauki a yi tunani, na tuna komai kuma kar a rikita komai. Jin daɗi mara kyau kamar jin nauyi ya lalace, kuma damar fahimi ta ƙaru kamar lokacin ƙuruciya. Bilobil ya fi magunguna da yawa tare da ginkgo, wannan magani ne, ba mummunan ba ne, na halitta ne kuma mai iko, sabili da haka ina jin girma. Kafin ya sha ginkoom, amma babu wani sakamako. Bayan ginkoom, Na kewaye dukkan sharri. Kuma Bilobil magani ne. Fiye da kudin shakka.

Yawancin likitoci suna ba da tabbacin cewa ginkgo itace cirewa shine kawai magani wanda ke inganta aikin hankali a cikin marasa lafiya tsofaffi. Koyaya, binciken ya kuma nuna cewa bayan dakatar da Bilobil a cikin marasa lafiya na wannan rukuni, ana ganin sake dawo da alamomin da suka shafi shekaru.

Bayanan magungunan sune magungunan Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant da Tanakan.

Ana amfani da magungunan Bilobil sune kwayoyi kamar:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memantal
• Maruks
• Memantinol
• Memikar.

Kafin amfani da analogues, nemi likita.

Yanayin ajiya da rayuwar shiryayye

Magungunan sun dace don amfani na shekaru uku. Kada ku bayar da dama ga yara, kariya daga haske. Zafin 200C.

Clinical da kungiyar magunguna

Mai hana H + -K + -ATPase. Magungunan ƙwayar cuta

Tsarin saki, abun da aka shirya da marufi

◊ Shigar ciki capsules gelatin mai wuya, girman No. 3, tare da farin jiki da shuɗi mai shudi, abubuwan da ke cikin capsules suna da murfin huda daga kusan fararen fari zuwa fararen mai laushi mai laushi ko shuɗi.

* rabeprazole, abu pellet 8.5% - 118 mg.

Mahalarta: sukarin sukari (sucrose - 99.83%, povidone - 0.17%) - 71.46 mg, sodium carbonate - 1.66 mg, talc - 1.77 mg, titanium dioxide - 0.83 mg, hypromellose - 14.75 mg.

Fitowa na kwasfa pellet: hypromellose phthalate - 15.94 mg, cetyl barasa - 1.59 mg.
Abinda ke ciki na kwalliyar wuya gelatin A'a 3: jikin kwalliya - titanium dioxide - 2%, gelatin - har zuwa 100%, kwalin capsule - titanium dioxide - 2%, fenti mai launin shuɗi - 0.0176%, ruwan ɗimbin lu'u-lu'u - 0.0051%, gelatin - har zuwa 100%.

5 inji mai kwakwalwa. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. 7 inji mai kwakwalwa. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali.

Guda 14. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali.

30 inji mai kwakwalwa - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali.

Aikin magunguna

Mai hana H + -K + -ATPase. Magungunan ƙwayar cuta

Rabeprazole sodium yana cikin rukuni na abubuwan antisecretory mahaɗan da aka samo daga benzimidazole. Rabeprazole sodium yana hana ɓoye ruwan 'ya'yan itace na ciki ta hana ƙanƙan H + / K + -Kaƙwalwa a saman ɗakunan sel na ciki.

H + / K + -ATPase shine hadaddun furotin wanda ke aiki azaman famfon na proton, saboda haka rabeprazole sodium shine mai hana pampon proton a ciki kuma ya toshe matakin karshe na samar da acid.

Wannan tasirin yana da matukar dogaro kuma yana haifar da murkushewar taskanin basal da tasirin shaye shaye na acid, komai damuwa. Rabeprazole sodium ba shi da kaddarorin anticholinergic.

Bayan gudanar da magana ta sodium rabeprazole a kashi 20 na MG, tasirin maganin maganin zai inganta ne a cikin awa 1.Hibaryewar basal da narkewar acid ɗin a cikin sa'o'i 23 bayan ɗaukar kashi na farko na sodium rabeprazole shine 69% da 82%, bi da bi, kuma yana zuwa awowi 48.

Wannan lokacin aikin magani ya wuce wanda T1 / 2 ke annabta (kimanin awa 1). Za'a iya bayanin wannan sakamako ta hanyar ɗaukar tsawon magunguna zuwa ga H + / K + -Taƙaƙƙen sel na parietal na ciki.

Ofimar tasirin hanawar rabeprazole sodium akan ɓoye acid ya kai ga garin Filato bayan kwana 3 na ɗaukar sodium rabeprazole. Lokacin da kuka dakatar da ɗaukar bayanan sirri an maido su cikin kwanaki 1-2.

Tasiri kan maida hankali ga gastrin a cikin jini na jini

A cikin gwaji na asibiti, marasa lafiya sun ɗauki rabeprazole sodium a cikin allurai na 10 ko 20 mg kowace rana don tsawon lokacin kulawa har zuwa watanni 43. Yawan ƙwayar gastrin a cikin jini na plasma ya ƙaru don makonni 2-8 na farko, wanda ke nuna tasirin sakamako akan ɓoye acid. Mayar da hankali na gastrin ya koma matakin farko, yawanci a cikin makonni 1-2 bayan katse magani.

Tasiri akan enterochromaffin-kamar sel

Lokacin nazarin samfurori na biopsy na ciki na mutum daga ƙwanƙwasa da ƙasan ciki, marasa lafiya 500 waɗanda suka karɓi rabeprazole sodium ko magani na kwatankwacin makonni 8, ci gaba da canje-canje a cikin tsarin ƙwayoyin halittar enterochromin-kamar ƙwayoyin cuta, tsananin cututtukan gastro, yawan cututtukan atrophic, cututtukan hanji na ciki ko yaduwar cutar Helicobacter ba gano.

A cikin nazarin fiye da marasa lafiya 400 waɗanda suka karbi sbeum rabeprazole (10 mg / rana ko 20 mg / rana) har zuwa shekara 1, abin da ya faru na hyperplasia ya kasance mai ƙanƙantar da kuma wanda yake daidai da wannan don omeprazole (20 mg / kg). Babu wani lamari na canje-canje na adenomatous ko ciwan carcinoid da aka lura cikin berayen.

Sakamakon tsarin rabeprazole sodium dangane da tsarin juyayi na tsakiya, cututtukan zuciya ko tsarin numfashi ba a gano su ba.

An nuna cewa rabeprazole sodium, lokacin da aka sha shi a kai a cikin kashi 20 MG na tsawon makonni 2, ba ya shafar aikin thyroid, metabolism metabolism, maida hankali kan ƙwaƙwalwar ƙwayar cuta na parathyroid a cikin jini, da kuma haɗuwa da cortisol, estrogen, testosterone, prolactin, glucagon, FSH, LH , renin, aldosterone da hormone girma.

Pharmacokinetics

Tsotsa da rarrabawa

Rabeprazole yana ɗaukar hanzari daga hanji, Cmax a cikin plasma jini an kai shi kimanin sa'o'i 3.5 bayan gudanarwa a kashi 20 na MG. Canje-canje a cikin Cmax a cikin jini, ƙimar AUC na rabeprazole sune layi a cikin kewayon allurai daga 10 zuwa 40 MG.

Cikakken bayanin bioavailability bayan sarrafa bakin a kashi 20 na MG (idan aka kwatanta da iv) kusan 52%. Bugu da kari, bioavailability bai canza tare da allurai na rabeprazole. Babu lokacin shan miyagun ƙwayoyi a lokacin rana, ko kuma gudanar da maganin hana daukar ciki na magance ɗaukar rabeprazole.

Shan miyagun ƙwayoyi tare da abinci mai ƙiba yana rage jinkirin rabeprazole na tsawon sa'o'i 4 ko fiye, duk da haka, babu Cmax ko yanayin canzawar canji.

Ulla rabeprazole ga ƙwayoyin plasma kusan kashi 97%.

Metabolism da excretion

Babban metabolite shine thioether (M1). Itewaƙwalwar metabolite mai aiki kawai shine desmethyl (M3), duk da haka, an ƙaddara shi a cikin ƙananan taro a cikin mahalarta binciken guda ɗaya bayan ɗaukar rabeprazole a kashi 80 MG.

Bayan kashi ɗaya na sodium 14C-wanda aka yiwa alama mai rabeprazole a kashi 20 na MG, ba a sami magungunan da ba su canza ba a cikin fitsari.

Kusan 90% na rabeprazole an keɓance ta ta hanyar kodan galibi a cikin nau'i biyu na metabolites: conjugate na mercapturic acid (M5) da acid acid na carbon (M6), da kuma a cikin nau'ikan metabolites guda biyu waɗanda ba a san su ba yayin nazarin toxicological. Ragowar sbeum rabeprazole da aka dauka yana kece ta cikin hanji.

Jimlar kawar da kashi 99.8%. Waɗannan bayanan suna nuna ɗan ƙaramin kewayon rabeprazole sodium metabolites tare da bile.

A cikin masu sa kai lafiya, plasma T1 / 2 kusan awa 1 ne (kama daga 0.7 zuwa awa 1.5), jimlar ɗaukar nauyin 3.8 ml / min / kg.

Pharmacokinetics a cikin rukunin masu haƙuri na musamman

A cikin marasa lafiya da lalacewar hanta na wucin gadi, AUC an ninka sau biyu idan aka kwatanta da masu ba da agaji na lafiya, wanda ke nuna raguwar metabolism yayin "wucewar farko", kuma T1 / 2 daga plasma jini yana ƙaruwa sau 2-3.

A cikin marasa lafiya da tsayayyen ƙarshen-matakin renal gazawar waɗanda suke buƙatar tabbatarwa hemodialysis (CC

• Capaya daga cikin kwandon Bilobil ya ƙunshi nauyin 40 na ganyayyaki daga ganyen bishiya ginkgo biyu mai haushi.
• Capaya daga cikin kwandon Bilobil Forte ya haɗa da nauyin 80 na cirewa daga ganyen bishiya ginkgo biyu mai haushi.

100 MG na cirewa ya hada da 19.2 MG ginkgo glycosides nau'in flavone da 4.

8 MG terpene lactones nau'in (bilobalides da ginkgolides).

Substancesarin abubuwa: colloidal silicon oxide, sitaci masara, lactose monohydrate, magnesium stearate, talc.

Harshen Shell: launin fenti mai farin ƙarfe, titanium dioxide, azorubine, baƙin ƙarfe baƙin ƙarfe, gelatin.

Fom ɗin saki

Pink gelatin capsules, a ciki ya ƙunshi foda mai launin shuɗi tare da barbashi mai duhu. 10 capsules a cikin boka, blister biyu ko shida a cikin fakitin kwali.

Aikin magunguna

Neurometabolic, antihypoxicwanda ke haɓaka microcirculation, haɓaka keɓaɓɓen wurare da na jijiyoyin hannu, angioprotective, maganin antioxidant aiki.

Magunguna da magunguna

Pharmacodynamics

Phytopreching, al'ada metabolism a cikin sel rheological alamomi jini da turare nama.

Yana haɓaka keɓaɓɓiyar ƙwayar cuta kuma yana samar da kwakwalwa glucose da oxygenyana hana tarawa ƙwayoyin jiniyana hana kunnawa countlet plate.

Yana da tasiri mai dogaro da iko akan tsarin jijiyoyin jiki, yana kunna samar KADA, yana fadada lumen arterioles, yana kara sautin jijiyoyi, ta haka ne yake cike gurbin jijiyoyin jini. Weakens permeability na jirgin ruwa bango.

Samun mallaka maganin ƙwayar cuta aiki (yana karfafa membranes na sel jini da platelet, yana tasiri biosynthesis) prostaglandinsyana raunana sakamako platelet-activation factor) Yana hana peroxidation na fats na membranes na tantanin halitta da samuwar tsattsauran ra'ayi.

Normalizes metabolism ƙwaƙwalwar ƙwaƙwalwa (kamar dopamine, norepinephrine da karafarini) Hakanan yana da antihypoxic aiki, yana ƙarfafa metabolism, yana haɓaka tarawa macroergsYana hanzarta zubar da abubuwa glucose da oxygenyana tsara hanyoyin shiga tsakani a cikin kwakwalwa.

Pharmacokinetics

Bayan shan bioavailability bilobalida da ginkgolides yana kashi 85%. Ana yin rikodin mafi girman sa'o'i biyu bayan shan miyagun ƙwayoyi. Cire rabin rayuwar shine 4-10 hours. Kwayoyin wadannan abubuwan ba su fashewa a cikin jiki kuma an kwashe su gaba daya tare da fitsari, zuwa wani kankanin - tare da feces.

Alamu don amfani

• Mai lalata microcirculation da kewaye wurare, Cutar Raynaud.

Encephalopathy Discirculatory saboda bugun jini, rauni, shekaru da sauran dalilai, tare da raunin ƙwaƙwalwar ajiya, hankali, raunin iyawar hankali, da kuma canji a tsarin bacci.

Contraindications

• Cutar gastritis.
• Rage coagulability.
• Hadarin cerebrovascular.
• Ciwon mara a cikin m lokaci.
• Saukar jini na Myocardial.
• Tsananin hankali ga abubuwanda ke tattare da maganin.
• Age zuwa shekaru 18.

Side effects

• Amfani daga aiki mai juyayi: rashin bacci, ciwon kairashin bacci, farin ciki.

Capsules (Allunan) Bilobil, umarnin don amfani

A encephalopathy rarrabuwa yi amfani da capsules 1-2 sau uku a rana.

A cikin jiyya take hakkimicrocirculation da kewaye wurare dabam dabam, Cutar Raynaud 1auki capsule 1 sau uku a rana.

A maganin ciwon sukari, ciwon zuciyashekaru dmaimaitawa bayar da shawarar kwalin kwalliya 1 sau uku a rana.

Yawan abin sama da ya kamata

Idan adadin ya wuce, sakamakon haɓakar halayen na iya inganta. Kulawar ta gargajiya ce, dangane da alamomin.

Umarni na musamman

Sakamakon warkewa na miyagun ƙwayoyi yana faruwa bayan kimanin wata guda da shan maganin. Idan a cikin lokacin da ake amfani da maganin ƙwayar cuta akwai lalacewa kwatsam, raunin ji, tinnitus ko danshi ya bayyana, dole ne ka dakatar da shan maganin kuma cikin gaggawa neman shawarar likita.

Ba'a ba da shawarar sanya Bilobil ga marasa lafiya waɗanda ke fama da cutar galactose ko glucose malabsorption syndrome, na nakasar galactosemia ko rashi na lactase, saboda lactose wani ɓangare ne na shi.

Hulɗa da ƙwayoyi

Bai kamata a rubuto Bilobil ga marasa lafiya waɗanda ke shan magungunan da ke rage ƙwaƙwalwar jini na jini (alal misali, acetylsalicylic acid da sauran magungunan anti-steroidal anti-inflammatory, kai tsaye da kuma kai tsaye kai tsaye). Irin wannan haɗuwa na iya ƙara haɗarin zubar jini saboda tsawan lokaci na coagulation.

Mun dauki wasu sharhi na mutane game da miyagun ƙwayoyi Bilobil:

1. Fatan alkhairi Bayan duban dan tayi na kwakwalwar kwakwalwa da jijiyoyin kwakwalwa, Bilobil Forte ya tsara likita, ya sha kusan shekara guda kuma ya kasa fahimtar dalilin da yasa matsin ya zama kasa da 10070, kuma hakan ya faru har kasa, kuma bugun yayi tsalle zuwa 120, taji dadi sosai, ta daina shan giya kuma a hankali komai ya zama domin ka samu sauki, har sai an warkar da daya kuma an gurgu, kana bukatar ka yi taka tsantsan da wannan maganin. Kiwan lafiya ga kowa.
2. Galina. Ta sha azumin wata daya, an fitar da ita daga osteochondrosis na mahaifa. Shugaban yana da gajimare, hangen nesa. Bai taimaka ba kwata-kwata.
3. Olga Na dauki capsules bayan bugun jini a kan shawarar likita don kawar da mummunan tasirin. "Bilobil" ya taimaka cire tinnitus da ingantaccen ƙwaƙwalwa.
4. Zina. Expensivearin tsada ba ya nufin mafi kyau! Bilobil Intens 120mg: fakitin 60 capsules yana da nauyin 970 rubles, farashin tanakan 40mg na allunan 90 na 1580, yayin da tanakan bai taimaka min ba, kuma Bilobil mai ƙarfi ya tashi. Matsalolin ƙwaƙwalwar ajiya suna buƙatar bayani a cikin nau'i mai inganci, ingantaccen magani. An bi da Bilobil tsanani kuma ba ni da matsalar ƙwaƙwalwar ajiya. Kuma kai baya zubewa, baya cutarwa. Amma babban abu shine cewa tare da bayyana a fili yana da sauƙin yin aiki da yin abubuwa yau da kullun.
5. Olya. Na sha tsawan watanni uku na bilobil tsanani. Jin dadi. Shugaban kaina ya zama mai haske, yana da sauki a yi tunani, na tuna komai kuma kar a rikita komai. Jin daɗi mara kyau kamar jin nauyi ya lalace, kuma damar fahimi ta ƙaru kamar lokacin ƙuruciya. Bilobil ya fi magunguna da yawa tare da ginkgo, wannan magani ne, ba mummunan ba ne, na halitta ne kuma mai iko, sabili da haka ina jin girma. Kafin ya sha ginkoom, amma babu wani sakamako. Bayan ginkoom, Na kewaye dukkan sharri. Kuma Bilobil magani ne. Fiye da kudin shakka.

Yawancin likitoci suna ba da tabbacin cewa ginkgo itace cirewa shine kawai magani wanda ke inganta aikin hankali a cikin marasa lafiya tsofaffi. Koyaya, binciken ya kuma nuna cewa bayan dakatar da Bilobil a cikin marasa lafiya na wannan rukuni, ana ganin sake dawo da alamomin da suka shafi shekaru.

Bayanan magungunan sune magungunan Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant da Tanakan.

Ana amfani da magungunan Bilobil sune kwayoyi kamar:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memantal
• Maruks
• Memantinol
• Memikar.

Kafin amfani da analogues, nemi likita.

Yanayin ajiya da rayuwar shiryayye

Magungunan sun dace don amfani na shekaru uku. Kada ku bayar da dama ga yara, kariya daga haske. Zafin 200C.

Clinical da kungiyar magunguna

Mai hana H + -K + -ATPase. Magungunan ƙwayar cuta

Tsarin saki, abun da aka shirya da marufi

◊ Shigar ciki capsules gelatin mai wuya, girman No. 3, tare da farin jiki da shuɗi mai shudi, abubuwan da ke cikin capsules suna da murfin huda daga kusan fararen fari zuwa fararen mai laushi mai laushi ko shuɗi.

* rabeprazole, abu pellet 8.5% - 118 mg.

Mahalarta: sukarin sukari (sucrose - 99.83%, povidone - 0.17%) - 71.46 mg, sodium carbonate - 1.66 mg, talc - 1.77 mg, titanium dioxide - 0.83 mg, hypromellose - 14.75 mg.

Fitowa na kwasfa pellet: hypromellose phthalate - 15.94 mg, cetyl barasa - 1.59 mg.
Abinda ke ciki na kwalliyar wuya gelatin A'a 3: jikin kwalliya - titanium dioxide - 2%, gelatin - har zuwa 100%, kwalin capsule - titanium dioxide - 2%, fenti mai launin shuɗi - 0.0176%, ruwan ɗimbin lu'u-lu'u - 0.0051%, gelatin - har zuwa 100%.

5 inji mai kwakwalwa. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. 7 inji mai kwakwalwa. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali.

Guda 14. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali. - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali.

30 inji mai kwakwalwa - fakiti mai bakin ciki (1, 2, 3) - fakitoci na kwali.

Aikin magunguna

Mai hana H + -K + -ATPase. Magungunan ƙwayar cuta

Rabeprazole sodium yana cikin rukuni na abubuwan antisecretory mahaɗan da aka samo daga benzimidazole. Rabeprazole sodium yana hana ɓoye ruwan 'ya'yan itace na ciki ta hana ƙanƙan H + / K + -Kaƙwalwa a saman ɗakunan sel na ciki.

H + / K + -ATPase shine hadaddun furotin wanda ke aiki azaman famfon na proton, saboda haka rabeprazole sodium shine mai hana pampon proton a ciki kuma ya toshe matakin karshe na samar da acid.

Wannan tasirin yana da matukar dogaro kuma yana haifar da murkushewar taskanin basal da tasirin shaye shaye na acid, komai damuwa. Rabeprazole sodium ba shi da kaddarorin anticholinergic.

Bayan gudanar da maganin baka na rabeprazole sodium a kashi 20 na MG, maganin antisecretory yana haɓakawa a cikin sa'a 1. Haramcin basal da haɓakar ƙwayar acid a cikin sa'o'i 23 bayan ɗaukar kashi na farko na sbeum rabeprazole shine 69% da 82%, bi da bi, kuma yana kai zuwa 48 hours.

Wannan lokacin aikin magani ya wuce wanda T1 / 2 ke annabta (kimanin awa 1). Za'a iya bayanin wannan sakamako ta hanyar ɗaukar tsawon magunguna zuwa ga H + / K + -Taƙaƙƙen sel na parietal na ciki.

Ofimar tasirin hanawar rabeprazole sodium akan ɓoye acid ya kai ga garin Filato bayan kwana 3 na ɗaukar sodium rabeprazole. Lokacin da kuka dakatar da ɗaukar bayanan sirri an maido su cikin kwanaki 1-2.

Tasiri kan maida hankali ga gastrin a cikin jini na jini

A cikin gwaji na asibiti, marasa lafiya sun ɗauki rabeprazole sodium a cikin allurai na 10 ko 20 mg kowace rana don tsawon lokacin kulawa har zuwa watanni 43. Yawan ƙwayar gastrin a cikin jini na plasma ya ƙaru don makonni 2-8 na farko, wanda ke nuna tasirin sakamako akan ɓoye acid. Mayar da hankali na gastrin ya koma matakin farko, yawanci a cikin makonni 1-2 bayan katse magani.

Tasiri akan enterochromaffin-kamar sel

Lokacin nazarin samfurori na biopsy na ciki na mutum daga ƙwanƙwasa da ƙasan ciki, marasa lafiya 500 waɗanda suka karɓi rabeprazole sodium ko magani na kwatankwacin makonni 8, ci gaba da canje-canje a cikin tsarin ƙwayoyin halittar enterochromin-kamar ƙwayoyin cuta, tsananin cututtukan gastro, yawan cututtukan atrophic, cututtukan hanji na ciki ko yaduwar cutar Helicobacter ba gano.

A cikin nazarin fiye da marasa lafiya 400 waɗanda suka karbi sbeum rabeprazole (10 mg / rana ko 20 mg / rana) har zuwa shekara 1, abin da ya faru na hyperplasia ya kasance mai ƙanƙantar da kuma wanda yake daidai da wannan don omeprazole (20 mg / kg). Babu wani lamari na canje-canje na adenomatous ko ciwan carcinoid da aka lura cikin berayen.

Sakamakon tsarin rabeprazole sodium dangane da tsarin juyayi na tsakiya, cututtukan zuciya ko tsarin numfashi ba a gano su ba.

An nuna cewa rabeprazole sodium, lokacin da aka sha shi a kai a cikin kashi 20 MG na tsawon makonni 2, ba ya shafar aikin thyroid, metabolism metabolism, maida hankali kan ƙwaƙwalwar ƙwayar cuta na parathyroid a cikin jini, da kuma haɗuwa da cortisol, estrogen, testosterone, prolactin, glucagon, FSH, LH , renin, aldosterone da hormone girma.

Pharmacokinetics

Tsotsa da rarrabawa

Rabeprazole yana ɗaukar hanzari daga hanji, Cmax a cikin plasma jini an kai shi kimanin sa'o'i 3.5 bayan gudanarwa a kashi 20 na MG. Canje-canje a cikin Cmax a cikin jini, ƙimar AUC na rabeprazole sune layi a cikin kewayon allurai daga 10 zuwa 40 MG.

Cikakken bayanin bioavailability bayan sarrafa bakin a kashi 20 na MG (idan aka kwatanta da iv) kusan 52%. Bugu da kari, bioavailability bai canza tare da allurai na rabeprazole. Babu lokacin shan miyagun ƙwayoyi a lokacin rana, ko kuma gudanar da maganin hana daukar ciki na magance ɗaukar rabeprazole.

Shan miyagun ƙwayoyi tare da abinci mai ƙiba yana rage jinkirin rabeprazole na tsawon sa'o'i 4 ko fiye, duk da haka, babu Cmax ko yanayin canzawar canji.

Ulla rabeprazole ga ƙwayoyin plasma kusan kashi 97%.

Metabolism da excretion

Babban metabolite shine thioether (M1). Itewaƙwalwar metabolite mai aiki kawai shine desmethyl (M3), duk da haka, an ƙaddara shi a cikin ƙananan taro a cikin mahalarta binciken guda ɗaya bayan ɗaukar rabeprazole a kashi 80 MG.

Bayan kashi ɗaya na sodium 14C-wanda aka yiwa alama mai rabeprazole a kashi 20 na MG, ba a sami magungunan da ba su canza ba a cikin fitsari.

Kusan 90% na rabeprazole an keɓance ta ta hanyar kodan galibi a cikin nau'i biyu na metabolites: conjugate na mercapturic acid (M5) da acid acid na carbon (M6), da kuma a cikin nau'ikan metabolites guda biyu waɗanda ba a san su ba yayin nazarin toxicological. Ragowar sbeum rabeprazole da aka dauka yana kece ta cikin hanji.

Jimlar kawar da kashi 99.8%. Waɗannan bayanan suna nuna ɗan ƙaramin kewayon rabeprazole sodium metabolites tare da bile.

A cikin masu sa kai lafiya, plasma T1 / 2 kusan awa 1 ne (kama daga 0.7 zuwa awa 1.5), jimlar ɗaukar nauyin 3.8 ml / min / kg.

Pharmacokinetics a cikin rukunin masu haƙuri na musamman

A cikin marasa lafiya da lalacewar hanta na wucin gadi, AUC an ninka sau biyu idan aka kwatanta da masu ba da agaji na lafiya, wanda ke nuna raguwar metabolism yayin "wucewar farko", kuma T1 / 2 daga plasma jini yana ƙaruwa sau 2-3.

A cikin marasa lafiya da tsayayyen ƙarshen-matakin renal gazawar waɗanda suke buƙatar tabbatarwa hemodialysis (CC

• Capaya daga cikin kwandon Bilobil ya ƙunshi nauyin 40 na ganyayyaki daga ganyen bishiya ginkgo biyu mai haushi.
• Capaya daga cikin kwandon Bilobil Forte ya haɗa da nauyin 80 na cirewa daga ganyen bishiya ginkgo biyu mai haushi.

100 MG na cirewa ya hada da 19.2 MG ginkgo glycosides nau'in flavone da 4.

8 MG terpene lactones nau'in (bilobalides da ginkgolides).

Substancesarin abubuwa: colloidal silicon oxide, sitaci masara, lactose monohydrate, magnesium stearate, talc.

Harshen Shell: launin fenti mai farin ƙarfe, titanium dioxide, azorubine, baƙin ƙarfe baƙin ƙarfe, gelatin.

Fom ɗin saki

Pink gelatin capsules, a ciki ya ƙunshi foda mai launin shuɗi tare da barbashi mai duhu. 10 capsules a cikin boka, blister biyu ko shida a cikin fakitin kwali.

Aikin magunguna

Neurometabolic, antihypoxicwanda ke haɓaka microcirculation, haɓaka keɓaɓɓen wurare da na jijiyoyin hannu, angioprotective, maganin antioxidant aiki.

Magunguna da magunguna

Pharmacodynamics

Phytopreching, al'ada metabolism a cikin sel rheological alamomi jini da turare nama.

Yana haɓaka keɓaɓɓiyar ƙwayar cuta kuma yana samar da kwakwalwa glucose da oxygenyana hana tarawa ƙwayoyin jiniyana hana kunnawa countlet plate.

Yana da tasiri mai dogaro da iko akan tsarin jijiyoyin jiki, yana kunna samar KADA, yana fadada lumen arterioles, yana kara sautin jijiyoyi, ta haka ne yake cike gurbin jijiyoyin jini. Weakens permeability na jirgin ruwa bango.

Samun mallaka maganin ƙwayar cuta aiki (yana karfafa membranes na sel jini da platelet, yana tasiri biosynthesis) prostaglandinsyana raunana sakamako platelet-activation factor) Yana hana peroxidation na fats na membranes na tantanin halitta da samuwar tsattsauran ra'ayi.

Normalizes metabolism ƙwaƙwalwar ƙwaƙwalwa (kamar dopamine, norepinephrine da karafarini) Hakanan yana da antihypoxic aiki, yana ƙarfafa metabolism, yana haɓaka tarawa macroergsYana hanzarta zubar da abubuwa glucose da oxygenyana tsara hanyoyin shiga tsakani a cikin kwakwalwa.

Pharmacokinetics

Bayan shan bioavailability bilobalida da ginkgolides yana kashi 85%. Ana yin rikodin mafi girman sa'o'i biyu bayan shan miyagun ƙwayoyi. Cire rabin rayuwar shine 4-10 hours. Kwayoyin wadannan abubuwan ba su fashewa a cikin jiki kuma an kwashe su gaba daya tare da fitsari, zuwa wani kankanin - tare da feces.

Alamu don amfani

• Mai lalata microcirculation da kewaye wurare, Cutar Raynaud.

Encephalopathy Discirculatory saboda bugun jini, rauni, shekaru da sauran dalilai, tare da raunin ƙwaƙwalwar ajiya, hankali, raunin iyawar hankali, da kuma canji a tsarin bacci.

Contraindications

• Cutar gastritis.
• Rage coagulability.
• Hadarin cerebrovascular.
• Ciwon mara a cikin m lokaci.
• Saukar jini na Myocardial.
• Tsananin hankali ga abubuwanda ke tattare da maganin.
• Age zuwa shekaru 18.

Side effects

• Amfani daga aiki mai juyayi: rashin bacci, ciwon kairashin bacci, farin ciki.

Umarnin don amfani (Hanyar da sashi)

Ya kamata a hadiye capsules gaba daya da ruwa. Kafin ka fara shan maganin ana bada shawarar yin shawara da likita. Alamar ci gaban alamun na iya bayyana bayan wata 1 na jiyya. Tsawon lokacin jiyya kada ya zama ƙasa da watanni uku.

Capsules (Allunan) Bilobil, umarnin don amfani

A encephalopathy rarrabuwa yi amfani da capsules 1-2 sau uku a rana.

A cikin jiyya take hakkimicrocirculation da kewaye wurare dabam dabam, Cutar Raynaud 1auki capsule 1 sau uku a rana.

A maganin ciwon sukari, ciwon zuciyashekaru dmaimaitawa bayar da shawarar kwalin kwalliya 1 sau uku a rana.

Umarnin don amfani da Bilobil Forte da Bilobil Intens 120

Ana daukar Bilobil Forte yawanci 1 kwalliya 1 sau biyu ko sau uku a rana, kuma ana daukar Bilobil Intens 120 sau 1 a lokaci (safe) ko sau 2 (safe da maraice) kowace rana.

Yawan abin sama da ya kamata

Babu wani rahoton rahoton da suka samu game da yawan ruwan sama.

Ra'ayoyi game da Bilobil

Binciken game da Bilobil Fort, Bilobil da Bilobil Intens suna da alaƙa da asali kuma, idan anyi amfani dasu daidai, suna nuna fa'idar da miyagun ƙwayoyi wajen inganta yaduwar ƙwayar cuta.

Binciken likitocin ya dogara ne akan wata hujja wacce ba za a iya tabbatarwa ba, wacce ke ba da shawarar cewa itacen Ginkgo cirewa kusan shine kawai sanannen kayan aiki wanda aka san shi wanda ke inganta aikin hankali a cikin marasa lafiyar tsofaffi.

Koyaya, binciken ya kuma nuna cewa alamun cututtukan da suka shafi shekaru suna iya komawa bayan cire magunguna.

Farashi, inda zaka siya

A Rasha, farashin Bilobil A'a 20 shine 156-211 rubles, farashin Bilobil Forte No. 20 shine 273-290 rubles, kuma farashin Bilobil Intens No. 20 yana farawa daga 418 rubles.

A cikin Ukraine, matsakaicin farashin waɗannan magungunan sune 99, 152 da 203 hryvnias, bi da bi.

• Magunguna kan layi a Rasha
• Magunguna kan layi a UkraineUkraine
• Magunguna kan layi a Kazakhstan

• Bilobil capsules 40 MG 60 inji mai kwakwalwa KRKA KRKA
• Bilobil forte capsules 80 MG 60 pcs KRKA KRKA
• Bilobil Intens capsules 120 mg 60 inji mai kwakwalwa KRKA KRKA
• Bilobil Intens capsules 120 MG MG 20 guda biyu KRKA KRKA
• Bilobil forte capsules 80 MG 20 inji mai kwakwalwa KRKA KRKA

• Bilobil 40mg A'a 20 capsules KRKA-Rus
• Bilobil Forte 80mg No. 60 capsules KRKA-Rus
• Bilobil 40mg No. 60 capsules KRKA-Rus
• Bilobil Forte 80mg A'a 20 capsules KRKA-Rus
• Bilobil Intense 120mg No. 60 capsules KRKA-Rus

Pharmacy IFC

• Bilobil Forte KRKA, Slovenia
• Bilobil Intens 120KRKA, Slovenia
• Bilobil Intens 120KRKA, Slovenia
• Bilobil Forte KRKA, Slovenia

• Bilobil forte capsules 80mg A'a 20KPKA (Slovenia)
• Kayakin Bilobil 40mg No. 60KPKA (Slovenia)
• Bilobil forte capsules 80mg No. 60KKKA (Slovenia)

Magungunan Pani

• Kauyukan Bilobil. 40mg A'a 20KKKA
• Kauyukan Bilobil. 40mg A'a 20KKKA
• Kauyukan Bilobil. 40mg A'a 20KKKA
• Kauyukan Bilobil. 40mg A'a 20KKKA

• Bilobil Intens 120 mg No. 60 iyakoki.
• Bilobil forte 80 mg No. 20 iyakoki.
• Bilobil forte 80 mg No. 60 iyakoki.

BAYAN HAKA! Bayani game da magunguna akan rukunin yanar gizon bayanai ne na tushen-tattarawa, an tattara su daga kafofin jama'a kuma ba za su iya zama tushen yanke hukunci game da amfani da magunguna ba yayin aikin jiyya. Kafin amfani da miyagun ƙwayoyi Bilobil, tabbatar tabbatar da likita.