Acetylsalicylic acid: umarnin don amfani

Acetylsalicylic acid, lokacin da aka saka shi, yana ba da gudummawa ga rushewar kwayar cutar ta prostaglandins, abubuwan da ke taka rawa sosai ga ci gaban jihohin febrile, matakai na kumburi da ciwo.

Ressionarfafa samar da prostaglandins yana haifar da fadada tasoshin jini, wanda ke taimakawa haɓaka rabuwa da gumi, wanda ke bayanin tasirin maganin ƙwayar cuta.

Amfani da magunguna dangane da acetylsalicylic acid a cikin warkarwa yana haifar da raguwa a cikin ƙimar jijiyoyin ƙoshin jijiyoyi, wanda ke bayyana tasiri na maganin wannan maganin. Acetylsalicylic acid an kewaya ta a cikin kodan.

Abinda ke taimaka wa acetylsalicylic acid

An tsara allunan acid na Acetylsalicylic ga manya don kula da hana yanayi mai zuwa:

M kumburi tafiyar matakai - kumburi da jakar zuciya, rheumatoid amosanin gabbai, qasar chorea, ciwon huhu da pleurisy a matsayin wani ɓangare na hadaddun farji, mai kumburi raunuka daga cikin jakar periarticular,
Ciwon ciki na asalin asali daban-daban - matsanancin ciwon kai, ciwon hakori, ciwon tsoka da mura da kuma kamuwa da cuta, ciwon ciki, ciwon kai, ciwon gwiwa,
Cututtukan kashin baya tare da ciwo mai zafi - osteochondrosis, lumbago,
Increaseara yawan zafin jiki, zazzabi saboda cututtukan da ke haifar da kumburi a cikin jiki,
Yin rigakafin haɓakar yaduwar ƙwayar cuta na cikin zuciya ko bugun jini na ischemic idan akwai damuwa na jijiyoyin jini, da jijiyoyin jini, da jini mai yawa,
Angina pectoris na yanayin rashin kwanciyar hankali,
Halittar kwayoyin halittar jini ga jini, thrombophlebitis,
Lahani a cikin zuciya, ƙwayar cuta mai ƙwaƙwalwar ƙwayar cuta (aiki mai rauni),
Saukar ciki na huhu, ƙwaƙwalwar ƙwayar huhu.

Contraindications

Allunan acid na Acetylsalicylic suna da contraindications da yawa don amfani. Wadannan sun hada da:

Hemorrhagic diathesis da vasculitis,
Cutar gastritis na lalacewa ko asalin lalacewa,
Peptic miki na ciki da duodenum,
Rashin wadataccen jini, yanayin zubar jini,
Rashin bitamin K
Exfoliating Aouric Aneurysm,
Cutar rashin lafiyar koda da hanta,
Sauke jini
Rashin haƙuri ɗaya na salicylates ko halayen rashin lafiyan ga acetylsalicylic acid a cikin tarihi
Yawan hauhawar jini, haɗarin bugun jini.

Acetylsalicylic acid yadda ake ɗauka?

Allunan acid na Acetylsalicylic sune don gudanar da maganin baka. Ana ba da shawarar cewa za a sha maganin a farkon cin abinci ko kuma nan da nan bayan an ci abinci domin a hana ci gaban lalacewa a cikin mucosa na ciki. Allunan za'a iya wanke su tare da madara, don haka tasirin fushi na acetylsalicylic acid akan ƙwayoyin mucous na narkewa ba zai zama mai tsaurin ra'ayi ko amfani da ruwan alkaline na yau da kullun ba tare da gas a cikin adadin da yawa.

An wajabta tsofaffi 1 kwamfutar hannu na 500 na kwayoyi sau 2-4 a rana, dangane da alamu da lafiyar gaba ɗaya. Matsakaicin adadin yau da kullun shine 3 g kuma baza a iya wuce shi ba! Tsawan lokacin magani tare da wannan magani yana ƙaddara ta likita dangane da alamu, tsananin zafin kumburi da halayen ɗabi'ar mutum, amma wannan lokacin bai wuce kwanaki 10-12 ba.

Don dalilai na prophylactic, don rage haɗarin haɓakar infitar cikin ƙananan ƙwayoyin cuta da na jini, an wajabta wa adults Allunan asfirin sau 1 a rana. Tsawon lokacin jiyya kusan watanni 1-2 ne. A wannan lokacin, ya zama dole a sanya ido a kai a kai a kai a kai a kai, a sanya ido a cikin jini, a sanya ido a kan yawan hadarin jini da yawan fararen hular.

Side effects

Kafin amfani da allunan acid na acetylsalicylic acid, mara lafiya ya kamata ya nemi likita. Idan kashi ya wuce ko ba a sarrafa shi ba kuma ya tsawaita amfani da wannan magani, waɗannan sakamako masu zuwa na iya haɓaka:

Ciwon zuciya, tashin zuciya, amai,
Zawo gudawa
Haushi da rauni
Rashin ci
Rashin gani,
Jinin jini - hanji, hanci, gingival, na ciki,
Canza hoton hoto na jini - raguwar adadin haemoglobin da platelet,
Take hakkin hanta da kodan,
A ci gaba da m renal gazawar,
Bronchospasm, a cikin mawuyacin yanayi, haɓakar angioedema da girgiza ƙwayar cuta.

Yin amfani da miyagun ƙwayoyi yayin daukar ciki da lactation

Magungunan acetylsalicylic acid an hana shi shan cikin watanni na 1 da na uku na ciki.

Dangane da bincike, amfani da allunan asfirin a cikin mata masu juna biyu a farkon makonni 12 na kara girman hadarin tasowa cikin amfrayo, wato, rufe farfajiya ta sama da lahani na zuciya.

Yin amfani da miyagun ƙwayoyi a cikin watanni na 2 yana yiwuwa tare da tsananin taka tsantsan kuma kawai idan amfanin da ake tsammanin zai yiwa mahaifiyar zai iya sama da cutar da tayi. Ana amfani da Allunan a gwargwadon takamaiman matakan magani (ƙarancin tasiri) kuma a ƙarƙashin kulawa mai tsafta. Yayin lokacin jiyya, mahaifiyar mai bukatar buƙatar yin gwajin jini akai-akai don tantance kirjin jini da ƙimar platelet.

An haramta amfani da acetylsalicylic acid a cikin watanni uku saboda wani hadarin da ke tattare da farkon shigowa aortic a cikin tayi. Bugu da kari, miyagun ƙwayoyi na iya haifar da basur a cikin ventricles na kwakwalwa a cikin tayin kuma ya haifar da haɗarin zubar da jini a cikin mahaifiyar mai tsammani.

An haramta amfani da allunan acid na acetylsalicylic acid yayin shayarwa saboda girman hadarin haɓakar hanta da koda a cikin jariri. Bugu da ƙari, shiga cikin jikin jariri tare da madarar uwa, acetylsalicylic acid na iya haifar da zubar jini mai ciki a cikin yaro. Idan ya zama dole a yi amfani da wannan magani yayin shayar da jarirai, ya kamata a juyar da jariri zuwa abincin da ke cikin wucin gadi tare da madaidaicin madara.

Yin hulɗa tare da wasu kwayoyi

Yin amfani da allunan asfirin a lokaci guda tare da wasu kwayoyi daga rukuni na abubuwanda basu da steroidal anti-inflammatory (ibuprofen, nuroferon, indomethacin da sauransu) yana kara haɗarin sakamako masu illa na gefen da aka lissafa a sama da alamun cutar rashin ƙarfi. A wasu halaye, marasa lafiya sun haɓaka hepatic da rashin cin nasara na koda da coma.

Tare da yin amfani da acetylsalicylic acid da kwayoyi daga rukunin antacid, an lura da raguwar tasirin maganin asfirin da rage gudu a cikin shanyewar jini.

Allunan acid na Acetylsalicylic acid an hana su shan su lokaci guda tare da maganin rashin nasara saboda karuwa mai yawa a cikin yiwuwar babban zubar jini a ciki da zub da jini mai zurfi.

Tare da amfani da layi daya na amfani da acetylsalicylic acid tare da diuretics, ingancin warkewarsu yana raguwa.

Amfani da wannan magani a lokaci guda tare da ethanol zai iya haifar da guba da maye gawar.

Adanawa da kuma isar da yanayin

Allunan acid na Acetylsalicylic acid ana ba su a cikin magunguna ba tare da takardar sayan magani ba. Ya kamata a adana miyagun ƙwayoyi shekaru 4 daga ranar da aka ƙera ya nuna akan kunshin. Bayan wannan lokacin, allunan ba za a iya ɗauka a baki ba.

Ka nisan da akwati nesa ba kusa da hasken rana kai tsaye da kuma isar yara ba.

Form sashi

Allunan, 500 MG

Tabletaya daga cikin kwamfutar hannu ya ƙunshi

abu mai aiki: acetylsalicylic acid - 500 MG

magabata: sitaci dankalin turawa, sitar acid, citric acid na citric acid, talc

Allunan, Flat-cylindrical Allunan, fararen fata, ɗakuna, ƙawataccen dutse, ɗan marmara

Kayan magunguna

Pharmacokinetics

Bayan gudanar da baki, acetylsalicylic acid ya juya zuwa cikin babban metabolite - salicylic acid. Kasancewar acetylsalicylic da salicylic acid a cikin narkewa na faruwa da sauri kuma gaba daya. Matsakaicin maida hankali ne akan plasma bayan minti 10-20 (acetylsalicylic acid) ko mintuna 45-120 (duka salicylates). Matsakaicin ɗaurin acid ta sunadarai na plasma ya dogara da maida hankali, wanda shine 49-70% don acetylsalicylic acid da kuma 66-98% don acid salicylic. Kashi 50% na maganin yana maganin metabolized yayin hanyar farko ta hanta.

Magungunan yana ƙetare shingen jini-kwakwalwa, kuma an ƙaddara shi a cikin madara da nono.

Metabolites na acetylsalicylic da salicylic acid sune glycine conjugate na salicylic acid, acid na Gentisic da glycine conjugate. Tsarin rayuwa na salicylates yana faruwa ne musamman a cikin hanta tare da samuwar manyan abubuwan metabolites 4 waɗanda aka samo a cikin kyallen takarda da fitsari da yawa. Rearar jijiyar salicylates ana gudanar da ita ne ta hanyar ɓoyewar aiki a cikin tubules na kodan ta hanyar da ba'a canza shi ba (60%) kuma a cikin hanyar metabolites. Matsakaicin fitarwar ya dogara da kashi - lokacin ɗaukar ƙananan allurai, rabin-rabin shine tsawon awanni 2-3, kuma tare da ƙaruwa cikin kashi na iya ƙaruwa har zuwa awanni 15-30. A cikin jarirai, kawar da salicylates yana da hankali sosai fiye da na manya. Sakamakon anti-mai kumburi da miyagun ƙwayoyi yana faruwa bayan kwanaki 1-2 na gudanarwa (bayan ƙirƙirar matakan warkewa na yau da kullun na salicylates a cikin kyallen, wanda shine kusan 150-300 μg / ml), ya kai matsakaici a taro na 20-30 mg% kuma tsawon lokacin amfani ya ragu.

Pharmacodynamics

Acetylsalicylic acid yana da anti-mai kumburi, antipyretic, sannan kuma sakamako mai narkewa.

An bayyana tasirin anti-mai kumburi na acetylsalicylic acid ta hanyar tasirin sa game da ayyukan da ke faruwa a cikin ƙwaƙwalwar ƙwayar cuta: raguwa a cikin ƙwarewar capillaries, raguwa a cikin ayyukan hyaluronidase, iyakancewar samar da makamashi na aikin kumburi ta hanyar hana samuwar ATP, da dai sauransu.

Tasirin antipyretic yana da alaƙa da tasiri akan cibiyoyin hypothalamic na thermoregulation.

Tasirin analgesic shine saboda tasirin tasirin cibiyoyin jin zafi da kuma damar salicylates don rage tasirin algogenic na bradykinin.

Ofaya daga cikin manyan hanyoyin aiwatar da acetylsalicylic acid shine inactivation (dakatar da aiki) na enzyme cyclooxygenase (enzyme da ke tattare da haɗin gwiwar prostaglandins), wanda sakamakon rikicewar aikin prostaglandins. Rashin aikin haɗin prostaglandin yana haifar da asarar hankali na ƙarshen jijiyoyin jijiya zuwa ga dangi da sauran matsin lamba da masu ba da labari na jin zafi (masu watsawa). Sakamakon cin zarafin kwayar cutar prostaglandins, tsananin zafin kumburi da kuma tasirin da suke dashi (haɓaka zafin jiki) tasirin ciwan thermoregulation yana raguwa. Bugu da ƙari, sakamakon prostaglandins akan ƙarar jijiyoyi yana raguwa, yana haifar da raguwa a cikin hankalinsu ga masu shiga tsakani na jin zafi. Hakanan yana da aikin rigakafin aiki.

Tasirin rigakafin magunguna shine rage karfin platelet da sauran kwayoyin jini su hada kai da rage yiwuwar thrombosis. Hanyar wannan matakin yana da alaƙa da toshe hanyoyin cyclooxygenase na arachidonic acid metabolism, hanawar enzymes na thromboxane synthetase, phosphodiesterase, karuwa a cikin cAMP a cikin platelet, raguwa a cikin matakan ƙwayar intracellular, inhibition of the syntheland of the intagins intanet abu mai aiki sosai (yaduwa ga tarawar platelet), karuwa a maida hankali ne adenosine a cr ova, toshewar maganin glycoprotein GP IIb / IIIa masu karɓa. Sakamakon haka, an hana haɗuwa da platelet, haɓakar ƙazamar ƙazuwarsu, ƙaruwa ta rheological jini, haɓakar thrombosis, microcirculation an daidaita shi. Ana samun mahimmancin hanawa na faranti na jini a allurai har zuwa 30 MG. Increara yawan aikin ƙwayar fibrinolytic na plasma kuma yana rage yawan haɗarin abubuwan da ke haifar da haɗuwa da jini na jini-K. Uri acid excretion yana motsawa a cikin allurai masu yawa, tunda reabsorption dinsa a cikin tubules na koda yana da illa.

Alamu don amfani

m rheumatic zazzabi, rheumatoid amosanin gabbai, pericarditis, Dressler ciwo, rheumatic chorea

m zuwa matsakaici ciwo ciwo (ciki har da ciwon kai, migraine, ciwon hakori, ciwo tare da osteoarthritis, amosanin gabbai, menalgia, algomenorrhea)

cututtuka na kashin baya tare da jin zafi (lumbago, sciatica)

increasedara yawan zafin jiki da sanyin sanyi da sauran cututtukan da ke kamuwa da kumburi (a cikin tsofaffi da yara kanana shekaru 15)

Sashi da gudanarwa

Acetylsalicylic acid ana ɗauka ta baki bayan cin abinci tare da ruwa mai yawa - ruwa, madara ko ruwa mai ma'adinai.

Tare da febrile da ciwo ciwo an bada shawara don ɗaukar 0.25 - 0.5 g / rana (1 / 2-1 shafin.) 3 - sau 6 a rana. Tsarin tazara tsakanin allurai yakamata ya zama akalla awanni 4. Matsakaicin ɗayan maganin 1 g .. Matsakaicin adadin yau da kullun shine 3,0 g.

Idan, yayin shan maganin acetylsalicylic acid na kwanaki 5, ciwo na ciwo ko na kwanaki 3 zazzabi ya ci gaba, ya kamata ka dakatar da magani kuma ka nemi likita.

Side effects

dizziness, tinnitus, rashin bacci

NSAID gastropathy: raunin epigastric, ƙwannafi, tashin zuciya, amai, zubar jini mai yawa a cikin narkewar abinci

thrombocytopenia, anemia, leukopenia

Reye / Reye syndrome (encephalopathy mai ci gaba: tashin zuciya da rashin jin daɗin ciki, gazawar numfashi, amai, amai, hanta mai ƙiba, hyperammonemia, haɓaka AST, ALT)

halayen rashin lafiyan: laryngeal edema, bronchospasm, urticaria, “asfirin” asma da kuma asfirin ”triad (eosinophilic rhinitis, recorrent hanci hanci polyposis, hyperplastic sinusitis)

Tare da amfani da tsawan lokaci:

interstitial nephritis, prezoal azotemia tare da ƙara creatinine a cikin jini da hypercalcemia, m renal failure, nephrotic syndrome

cututtukan jini (anaemia, agranulocytosis, thrombocytopenic purpura)

symptomsarin alamun bayyanar zuciya, ambaliyar jiki

ƙara matakan aminotransferases a cikin jini.

Mu'amala da Lafiya

Tare da yin amfani da acetylsalicylic acid tare da shirye-shiryen acid na valproic, cephalosporins ko anticoagulants, haɗarin zubar jini yana ƙaruwa. Tare da yin amfani da magunguna tare da NSAIDs a lokaci ɗaya, babban tasiri da sakamako na ƙarshen ƙarshen suna haɓaka.

A bangon maganin magani, sakamako na sakamako na methotrexate yana daɗaɗawa (lokacin ɗaukar ɗayan fiye da 15 MG / mako. - Acetylsalicylic acid yana contraindicated).

Tare da yin amfani da lokaci ɗaya tare da kwayoyi na hypoglycemic na baki - abubuwan da aka samo na sulfonylurea - akwai karuwa a cikin tasirin hypoglycemic.

Tare da yin amfani da lokaci guda tare da glucocorticosteroids, yin amfani da barasa, haɗarin zubar jini na haɓaka.

Magungunan sun raunana tasirin spironolactone, furosemide, antihypertensive da anti-gout jami'ai waɗanda ke haɓaka fitowar uric acid.

Gudanar da maganin rigakafi a lokacin jiyya tare da magani (musamman a allurai fiye da 3.0 g na manya) na iya haifar da raguwa a cikin babban matakin kwanciyar hankali na salicylate a cikin jini.

Umarni na musamman

Acetylsalicylic acid yana kara haɗarin zub da jini koda lokacin shan ƙananan allurai kuma tsawon kwanaki bayan shan shi. Kafin kowane aikin tiyata, sanar da likitanka, likitan tiyata, likitan dabbobi ko likitan hakora game da shan Acetylsalicylic acid. Kwana 5-7 kafin a yi masa tiyata, ya zama dole a soke liyafar (don rage zubar jini yayin aikin da kuma bayan aikin). A yayin da za'a dauki dogon lokaci ana bada magani, ana bada shawarar yin gwajin jini akai-akai da kuma duba yiwuwar jinin sihiri.

Tare da maganin anticoagulation na lokaci guda tare da acetylsalicylic acid a cikin ƙananan allurai, an rage yawan uric acid, wanda zai iya zama sanadin gout.

Amfani da yara Kada a rubuta kwayar cutar acetylsalicylic acid ga yara 'yan ƙasa da shekaru 15 tare da matsanancin cututtukan numfashi da ke haifar da cututtukan hoto, tare da cututtuka tare da hauhawar jini sakamakon haɗarin haɓaka cutar Reye / Ray sy).

Siffofin tasiri na miyagun ƙwayoyi akan karfin tuka abin hawa ko ƙwararrun haɗari

Babu wata alamar tasirin sakamako akan hankalin mai aiki, akan aikin motsa jiki da kuma sauyawar abubuwa.

Yawan abin sama da ya kamata

Ccututtuka: danshi, wahayi mai gani da ji, tashin zuciya, amai, haɓaka numfashi. Daga baya, akwai rashin kwanciyar hankali na hankali har zuwa coma, gazawar numfashi, raunin acid-base balance (alkalo na hucin hanji, sannan acidosis metabolic), gazawar asali na koda (ARF), girgiza. Mutuwar maye tana yiwuwa lokacin ɗaukar kashi 200 zuwa 500 MG / kg.

Jiyya: haifar da amai ko lalaci na ciki, rubutaccen gawayi, laxatives. Ya kamata a gudanar da jiyya a cikin sashe na musamman.

Fitar saki da kuma kwantena

Allunan kwayoyi 500

Allunan 10 ana sanya su a cikin kwano na bezeljakovoj marufi takarda tare da rufin polyethylene.

100 fakiti bezjacheykovy tare da madaidaitan adadin umarnin don amfani da magani a cikin jihohi kuma an sanya harsunan Rasha a cikin kwali daga akwatin kwali (fakitin rukuni).

Rijistar Rijistar Rijistar

Marbiopharm OJSC, Tarayyar Rasha

Adireshin kungiyar wanda ya yarda da da'awar daga masu sayayya kan ingancin kayayyaki (kayayyaki) a Jamhuriyar Kazakhstan

Tarayyar Rasha, 424006, Republic of Mari El, Yoshkar-Ola,

Waya: (8362) 42-03-12, fax: (8362) 45-00-00

Pharmacology

Yana hana cyclooxygenase (COX-1 da COX-2) kuma ba tare da izini ba yana hana hanyar cyclooxygenase na arachidonic acid metabolism, yana toshe hanyar haɗin PG (PGA₂PGD₂, PGF_2alphaPGE₁PGE₂ da sauransu) da thromboxane. Yana rage hyperemia, exudation, permeability capillary, aikin hyaluronidase, yana iyakance samar da makamashi na aikin kumburi ta hanyar hana samar da ATP. Ana rinjayar cibiyoyin subcortical na thermoregulation da ƙwarewar jin zafi. Rage GHG (galibi PGE₁ ) a cikin tsakiyar thermoregulation yana haifar da raguwa a cikin zafin jiki saboda yaduwar tasoshin jini na fata da haɓaka gumi. Tasirin analgesic shine saboda tasirin tasirin cibiyoyin jin zafi, da kuma matakin kariya na kumburi da kuma damar salicylates don rage tasirin algogenic na bradykinin. Thromboxane Ragewa₂ A cikin platelet yana kaiwa zuwa ga hanawa na hanawa da tarawa, dan kadan ya rage jijiyoyin jini. Tasirin antiplatelet yaci gaba har tsawon kwana 7 bayan kashi daya. Yawancin bincike na asibiti sun nuna cewa an sami mahimmancin hanawa na faranti jini zuwa allurai har zuwa 30 MG. Increara yawan ƙwayar fibrinolytic na plasma kuma yana rage yawan haɗarin abubuwan da ke tattare da haɗarin coagulation na Vitamin (II, VII, IX, X). Yana tayarda jijiyoyin uric acid, tunda yake sake gyara yanayin tubules din koda.

Bayan gudanar da baki, yana da isasshen abin tunawa. A gaban membrane mai shiga jiki (mai tsayayya da aikin ruwan 'ya'yan itace na ciki kuma baya bada izinin sha na acetylsalicylic acid a cikin ciki), yana shiga cikin babban ɓangaren ƙananan hanjin. Yayin sha, yana yin amfani da tsarin kawarda ciki a jikin bango na hanji da na hanta (ya lalata). Yankin da aka kwashe yana ɗaukar ruwa sosai da sauri ta hanyar esterases na musamman, saboda haka, T_1/2 acetylsalicylic acid bai wuce minti 15-20 ba. Yana yadawa a jiki (75-90% saboda albumin) kuma ana rarraba shi cikin kyallen a matsayin anion na salicylic acid. C_max Acetylsalicylic acid a zahiri bashi da alaƙa ga furotin plasma. A lokacin biotransformation, ana kirkirar metabolites a cikin hanta wanda aka samo a cikin kyallen takarda da fitsari da yawa. Rearar jijiyar salicylates ana gudanar da ita ne ta hanyar ɓoyewar aiki a cikin tubules na kodan ta hanyar da ba ta canzawa da kuma yanayin metabolites. Harshen abubuwan da ba su canzawa ba da kuma metabolites ya dogara da pH na fitsari (tare da alkinta fitsari, ionization na salicylates yana ƙaruwa, farfadowarsu yana ƙaruwa, kuma haɓakawa yana ƙaruwa sosai).

Amfani da sinadarin Acetylsalicylic acid

IHD, kasancewar abubuwa masu haɗari da yawa ga IHD, raunin myocardial ischemia mai raɗaɗi, angina mai tsayayyar rauni, myocardial infarction (don rage haɗarin infarction na myocardial na baya bayan mutuwa), ƙwaƙwalwar ƙwaƙwalwar ƙwayar cuta mai kwakwalwa da kuma ischemic a cikin maza, ƙwaƙwalwar zuciya mai taɓin hankali (rigakafin jiyya da cutar thromboemlis) , balloon coronary angioplasty da kuma stent placement (rage hadarin sake-sa maye da kuma lura da sutturar sakandare na jijiyoyin zuciya), da kuma cututtukan da ba na atherosclerotic na cututtukan jijiyoyin zuciya ry (Kawasaki cuta), aortoarteriit (Takayasu cuta), mitral bawul lahani na zuciya da kuma atrial fibrillation, mitral bawul prolapse (thromboembolism prophylaxis), maimaita na huhu embolism, Dressler ta ciwo, na huhu infarction, m thrombophlebitis. Zazzaɓi don kamuwa da cuta da cututtuka masu kumburi. Raunin ciwo na rauni da matsakaici na asali daban-daban, ciki har da cututtukan thoracic radicular, lumbago, migraine, ciwon kai, neuralgia, ciwon hakori, myalgia, arthralgia, algomenorrhea. A cikin rigakafi na asibiti da kuma allergology, ana amfani da shi a hankali wajen samar da allurai don tsawaitawar “asfirin” da kuma tsayayyar haƙuri ga NSAIDs a cikin marasa lafiya da ke dauke da “asfirin” ashma da kuma asfirin.

Dangane da alamu, rheumatism, rheumatic chorea, rheumatoid amosanin gabbai, cututtukan ƙwayar cuta-myocarditis, pericarditis - a yanzu ana amfani da su sosai.

Haihuwa da lactation

Amfani da manyan allurai na salicylates a farkon farkon haihuwa yana da alaƙa da karuwar mitar tayi na lalacewar haihuwa (ɓacin sararin, lakar zuciyar). A cikin karo na biyu na ciki, ana iya ba da umarnin yin amfani da sutturar salula ba tare da yin la'akari da kimanta haɗarin da fa'ida ba. Nadin salicylates a cikin uku na ciki na ciki ya haɗu.

Salicylates da metabolites ɗin su a cikin adadi kaɗan sun shiga cikin madara. Yawan cin abinci mai gishiri a lokacin shayarwa baya tare da haɓakar halayen da ake samu a cikin yaro kuma baya buƙatar daina shayarwa. Koyaya, tare da tsawan amfani da shi ko gudanarwa a cikin manyan allurai, ya kamata a daina shayar da jarirai.

Umarnin don amfani da Acetylsalicylic acid, sashi

Allunan anyi niyya don amfani da baki - ana bada shawara don cin abinci bayan madara, ruwan al'ada ko ruwan alkaline.

Doayyadaddun matakan acetylsalicylic acid bisa ga umarnin don amfani ga manya - daga 500 MG zuwa 1 g (Allunan 1-2) har zuwa sau 4 a rana.

Matsakaicin sashi ɗaya shine gram 1 (Allunan 2).
Matsakaicin adadin yau da kullun shine 3 grams (Allunan 6)

Don inganta halayyar rheological jini, kazalika da mai hana garkuwar platelet, ana sanya rabin allunan acetylsalicylic acid kowace rana tsawon watanni.

Tare da infarction na myocardial da don rigakafin infarction na sakandare na myocardial, ana bada shawara don ɗaukar 250 mg kowace rana.

Rikicewar rikicewar rikicewar ƙwayar cuta da ƙwayoyin cuta na cerebral thromboembolism suna ba da shawarar shan rabin kwamfutar hannu tare da daidaitawa da hankali na kashi zuwa allunan 2 na Acetylsalicylic acid kowace rana.

Side effects

Koyarwar tayi kashedin game da yuwuwar samun ci gaban sakamako masu zuwa yayin rubuta Acetylsalicylic acid:

zafin zuciya, tashin zuciya, amai,
zawo
tsananin fushi da rauni
asarar ci
rashin gani,
zub da jini - hanji, hanci, gingival, na ciki,
wani canji a hoto na asibiti - raguwa a yawan haemoglobin da platelet,
rikicewar hanta da hanta,
ga cigaban m renal gazawar,
bronchospasm, a cikin mawuyacin yanayi, haɓakar angioedema da tashin hankali anaphylactic.

Contraindications

Acetylsalicylic acid yana cikin contraindicated a cikin wadannan halaye:

na ciki,
asfirin triad,
da kumburi na erosive da ulcerative raunuka na narkewa kamar,
halayen da ake amfani da su na acetylsalicylic acid da sauran magungunan anti-mai kumburi a cikin cututtukan urticaria da rhinitis,
basur na jini,
hawan jini
hypoprothrombinemia,
saukar karfin jini
hauhawar jini, hadarin bugun jini,
mai sassauci aortic sabour,
rashin ƙarfi na glucose-6-phosphate,
Rashin bitamin K
na koda da hanta gazawar,
Raunin Reye.

Hakanan, maganin yana cikin contraindicated a cikin mata masu juna biyu, a lokacin lactation kuma tare da ƙara ji da hankali ga abubuwan da aka gyara.

Ba a amfani da Acetylsalicylic acid don kula da yara da matasa waɗanda ke fama da rashin lafiya ko murmurewa daga cutar tarin fuka da mura, tunda haɓakar encephalopathy mai saurin cutar na yiwuwa.

Yawan abin sama da ya kamata

Doarin yaduwar Acetisalicylic acid yana tare da isasshen acid-base da ma'aunin lantarki. Nausea, amai, jin zafi a cikin yankin na epigastric, an rage yawan ji da gani acuity.

Tunanin rashin tunani, rikice-rikice, rawar jiki, bacci, bushewar ciki, amsawar alkaline, coma, acidosis na rayuwa, da kuma keta hadarin metabolism shima hakan zai yiwu.

Kulawa ya dogara da hanzarta kawar da miyagun ƙwayoyi, kazalika da daidaituwa na ma'aunin acid-base.

Analogs Acetylsalicylic acid, farashin a cikin kantin magani

Idan ya cancanta, zaku iya maye gurbin Acetylsalicylic acid tare da kwatankwacin alamar abu mai aiki - waɗannan magunguna ne:

Lokacin zabar analogues, yana da mahimmanci a fahimci cewa umarnin don amfani da acetylsalicylic acid, farashin da sake dubawa na kwayoyi tare da tasirin irin wannan ba su amfani ba. Yana da mahimmanci don samun shawarar likita kuma kada kuyi canjin magani mai yanci.

Farashi a cikin magunguna na Rasha: Allunan Acetylsalicylic acid 500mg 10pcs. - daga 4 zuwa 9 rubles, allunan 20 - daga 15 zuwa 21 rubles, bisa ga magunguna 592.

A nisantar da kananan yara a yanayin zafi da basa wuce + 25 ° C. Rayuwar shelf shine shekaru 4. Sayarwa a cikin magunguna ba tare da takardar sayan magani ba.