Metfogamma 1000: umarnin don amfani, farashi, allunan sukari analogues

Metfogamma 1000 (Allunan) Rating: 8

Mai masana'anta: Vörwag Pharma GmbH & Co. KG (Jamus)
Siffofin Saki:

  • Allunan 1000 MG, guda 30., Farashin daga 176 rubles
Farashin Metfogamma 1000 a cikin kantin magani na kan layi
Umarnin don amfani

Wani magani don ciwon sukari a cikin sakin kwamfutar hannu wanda aka saki. Sanarwa a cikin kwali na kwali na allunan 30 dauke da metformin hydrochloride azaman sashi mai aiki. Contraindicated a lokacin daukar ciki da kuma nono.

Farashi da ka'idodin aikin magani

Nawa ne magani? Farashin ya dogara da adadin metformin a cikin ƙwayoyi. Don Metfogamma 1000 farashin shine 580-640 rubles. Metfogamma 500 MG farashin kimanin 380-450 rubles. A kan Metfogamma 850 farashin yana farawa daga 500 rubles. Yana da mahimmanci a lura cewa magungunan ana ba da sanarwar ne kawai ta hanyar takardar sayan magani.

Suna yin magani a Jamus. Ofishin wakilin hukuma yana can cikin Moscow. A cikin shekarun 2000, an kafa masana'antar magani a cikin garin Sofia (Bulgaria).

Mene ne ka'idodin aikin magani? Metformin (bangaren maganin yana aiki) yana rage maida hankali kan glucose a cikin jini. Ana samun wannan ta hanyar dakatar da gluconeogenesis a cikin hanta. Metformin kuma yana haɓaka amfani da glucose a cikin kyallen takarda da rage yawan sukari daga narkewa.

Abin lura ne cewa lokacin amfani da maganin, matakan cholesterol da LDL a cikin ƙwayar jini yana raguwa. Amma Metformin ba ya canza taro na lipoproteins. Lokacin amfani da magani zaka iya rasa nauyi. Yawanci, ana amfani da metogram 500, 850, da 100 mg lokacin cin abinci baya taimakawa rage girman jiki.

Metformin ba wai kawai yana rage sukarin jini ba, har ma yana inganta mahimman abubuwan da ke cikin fibrinolytic na jini.

An samu wannan ta hanyar kashe ƙwayar plasminogen mai nau'in nama.

Umarnin don amfani da miyagun ƙwayoyi

A cikin wane yanayi ne yin amfani da maganin Metfogamma 500 ya barata? Umarnin don yin amfani da shi ya ce ya kamata a yi amfani da maganin a cikin jiyya na cututtukan cututtukan cututtukan da ba na insulin-2 ba. Amma Metfogamma 1000, 500 da 800 MG ya kamata a yi amfani da su wajen kula da marasa lafiyar da ba su da haɗari ga ketoacidosis.

Yadda za a sha maganin? An zabi sashi ne gwargwadon matakin glucose a cikin jini. Yawancin lokaci, kashi na farko shine 500-850 MG. Idan ana amfani da maganin don kula da matakan sukari na yau da kullun, to, maganin yau da kullun na iya ƙaruwa zuwa 850-1700 MG.

Kuna buƙatar ɗaukar magani a cikin allurai biyu. Har yaushe zan sha maganin? Don Metfogamma 850, koyarwar ba ta tsara tsawon lokacin maganin ba. An zaɓi tsawon lokacin magani da akayi daban-daban kuma ya dogara da dalilai da yawa.

A cikin Metfogamma 1000, umarnin yin amfani da shi ya tsara irin wannan dokar don amfani:

  • Ketoacidosis mai ciwon sukari.
  • Bala'i a cikin aikin kodan.
  • Rashin zuciya.
  • Hadarin Cerebrovascular.
  • Al'adun shan giya
  • Fitsari.
  • Matsakaicin lokaci na ta infassation na zuciya.
  • Dysfunction hanta.
  • Barasa giya.
  • Lactic acidosis
  • Ciki
  • Lokacin lactation.
  • Allergy zuwa metformin da kayan taimako na miyagun ƙwayoyi.

Binciken likitocin ya nuna cewa bai kamata a yi amfani da maganin ba yayin rage kalori, wanda ya ƙunshi yawan ƙona adadin kuzari 1000 a rana. In ba haka ba, magani na Metfogamma 1000 na iya haifar da rikice-rikice, har zuwa cutar siga.

Yawancin lokaci ana haƙuri da maganin sosai. Amma tare da yin amfani da miyagun ƙwayoyi na tsawan lokaci, da alama tasirin sakamako kamar su:

  1. Megaloblastic anemia.
  2. Lationsarya a cikin aikin narkewa. Metfogamma 1000 na iya haifar da ci gaban bayyanar cututtuka, tashin zuciya, amai da gudawa. Hakanan yayin maganin jiyya, dandano mai ƙarfe na iya bayyana a bakin.
  3. Hypoglycemia.
  4. Lactic acidosis.
  5. Allergic halayen.

Haɓaka lactic acidosis yana nuna cewa ya fi kyau katse hanyar kulawa.

Idan wannan rikitarwa ta faru, dole ne a dauki magani nan da nan.

Hadin gwiwar Magunguna da Magunguna

Yaya metfogamma 1000 ke hulɗa tare da wasu kwayoyi? Umarnin ya ce maganin na iya rage tasirin magani tare da amfani da maganin rashin amfani da magani.

Ba'a ba da shawarar yin amfani da magani don ciwon sukari tare da masu hana MAO, masu hana ACE, abubuwan asali na clofibrate, cyclophosphamides ko beta-blockers. Tare da hulɗa da metformin tare da magungunan da ke sama, haɗarin ƙara yawan hypoglycemic mataki yana ƙaruwa.

Mene ne mafi ingancin analogues na Metfogamma 1000? A cewar likitoci, mafi kyawun madadin sune:

  • Glucophage (220-400 rubles). Wannan magani yana da kyau kamar Metfogamma. Abubuwan da ke aiki na kwayoyi suna aiki da metformin. Magungunan yana taimakawa rage yawan sukari na jini da haɓaka hankalin masu karɓar insulin na gefe.
  • Glibomet (320-480 rubles). Magungunan yana hana lipolysis a cikin tsopose nama, yana motsa hankalin jijiyoyin jijiyoyi zuwa aikin insulin kuma yana rage sukarin jini.
  • Siofor (380-500 rubles). Magungunan yana hana shan glucose a cikin hanji, yana inganta amfani da sukari a cikin ƙwayar tsoka kuma yana rage samar da glucose a cikin hanta.

An bada shawarar magungunan da ke sama don amfani dasu tare da nau'in ciwon sukari na ainihi-2. Lokacin zabar analog, ya kamata ka nemi likitanka, tunda magunguna don rage glucose na iya haifar da lactic acidosis. Bidiyo a cikin wannan labarin ya ci gaba da taken amfani da Metformin don ciwon sukari.

Analogs na maganin Metfogamma 1000

Analog ne mai rahusa daga 66 rubles.

Mai masana'anta: Merck Sante SAA.S. (Faransa)
Siffofin Saki:

  • Allunan 500 MG, 30 inji mai kwakwalwa., Farashin daga 110 rubles
  • Allunan 1000 MG, 30 inji mai kwakwalwa., Farashin daga 185 rubles
Farashin Glucophage a cikin magunguna kan layi
Umarnin don amfani

Magungunan Faransa don maganin cututtukan type 2. Sanarwa a cikin allunan da ke kunshe daga 500 zuwa 1000 MG na metformin a matsayin babban sinadari mai aiki. Akwai contraindications, sabili da haka, kafin ɗaukar Glucofage, ya zama dole a nemi shawara tare da gwani.

Analog ne mai rahusa daga 67 rubles.

Mai masana'anta: Akrikhin (Russia)
Siffofin Saki:

  • Allunan 500 MG, pcs 60., Farashin daga 109 rubles
  • Allunan 850 MG, pcs 60., Farashin daga 190 rubles
Farashin Gliformin a cikin kantin magani na kan layi
Umarnin don amfani

Gliformin magani ne na gida don lura da ciwon sukari na 2. Sanarwa a cikin nau'ikan Allunan tare da metformin a matsayin babban kayan aiki mai aiki (sashi na 250 ko 500 MG yana yiwuwa). Gliformin yana da jerin abubuwan contraindications, don haka kafin fara magani, tabbatar da karanta umarnin hukuma don amfani.

Analog mai rahusa daga 119 rubles.

Mai masana'anta: Pharmstandard-Leksredstva (Russia)
Siffofin Saki:

  • Tab. 50 MG, 30 inji mai kwakwalwa., Farashin daga 57 rubles
  • Tab. 50 MG, pcs 60., Farashin daga 99 rubles
Farashin Formetin a cikin magunguna kan layi
Umarnin don amfani

Formmetin shine mafi ƙarancin kuɗi don Glucofage, wanda aka tsara don rage glucose jini. Akwai shi a cikin allunan dauke da 0.5, 0.85 ko 1 g na metformin. Zai iya haifar da raunin tsarin narkewa, fatar jiki, kuma idan ya kasance yawan zubar jini - hypoglycemia da lactic acidosis tare da sakamako mai yuwuwar mutuwa.

Analog ya fi tsada daga 2 rubles.

Mai masana'anta: Hemofarm A.D. (Serbia)
Siffofin Saki:

  • Tab. 500 MG, pcs 60., Farashin daga 178 rubles
  • Tab. 50 MG, pcs 60., Farashin daga 99 rubles
Farashin Metformin a cikin kantin magani na kan layi
Umarnin don amfani

Metformin magani ne na Serbian hypoglycemic don amfani na ciki. Abun da ke tattare da Allunan yana dauke da sinadaran aiki mai suna iri ɗaya a cikin adadin 500 ko 850 MG. An wajabta don maganin cututtukan type 2 (a cikin manya), musamman ma a cikin lokuta masu kiba.

Analog ya fi tsada daga 209 rubles.

Mai masana'anta: Kimika Montpellier S.A. (Argentina)
Siffofin Saki:

  • Allunan 1000 MG, pcs 60., Farashin daga 385 rubles
  • Tab. 50 MG, pcs 60., Farashin daga 99 rubles
Farashin Bagomet a cikin magungunan kan layi
Umarnin don amfani

Magungunan ƙwayar ƙwayar ƙwayar cuta ta Argentina don maganin ciwon sukari. Aikin Bagomet ya dogara da amfani da metformin hydrochloride a cikin adadin 500 MG kowace kwamfutar hannu. An wajabta shi don nau'in ciwon sukari na 2.

Analogs a cikin kayan haɗin da nuni don amfani

TakeFarashi a RashaFarashi a Ukraine
Bagomet Metformin--30 UAH
Glucofage metformin12 rub15 UAH
Glucophage xr metformin--50 UAH
Reduxin Metformin, Sibutramine20 rub--
Dianormet --19 UAH
Diaformin metformin--5 UAH
Metformin metformin13 rub12 UAH
Metformin sandoz metformin--13 UAH
Siofor 208 rub27 UAH
Tsarin Hanyar Hanya na Hydrochloride----
Emformorm EP Metformin----
Megifort Metformin--15 UAH
Metamine Metformin--20 UAH
Metamine SR Metformin--20 UAH
Tefor metformin----
Glycometer ----
Glycomet SR ----
Formethine 37 rub--
Metformin Canon metformin, ovidone K 90, sitaci masara, crospovidone, magnesium stearate, talc26 rub--
Insuffor metformin hydrochloride--25 UAH
Metformin-teva metformin43 rub22 UAH
Diaformin SR metformin--18 UAH
Mepharmil Metformin--13 UAH
Metformin Farmland Metformin----

Jerin da aka bayar na magungunan analogues na miyagun ƙwayoyi, wanda ke nuna madadin metfogamma, ya fi dacewa saboda suna da tsari iri ɗaya na abubuwa masu aiki da daidaituwa bisa ga nuni don amfani

Abun daban-daban, na iya daidaituwa cikin nuni da hanyar aikace-aikace

TakeFarashi a RashaFarashi a Ukraine
Rosiglitazone mai mahimmanci, metformin hydrochloride----
Glibenclamide Glibenclamide30 rub7 UAH
Maninyl Glibenclamide54 rub37 UAH
Glibenclamide-Kiwon lafiya Glibenclamide--12 UAH
Karawancin glycidone94 rub43 UAH
Bisogamma Glyclazide91 rub182 UAH
Glidiab Glyclazide100 rub170 UAH
Mai ciwon sukari MR --92 UAH
Diagnizide mr Gliclazide--15 UAH
Glidia MV Gliclazide----
Glykinorm Gliclazide----
Gliclazide Gliclazide231 rub44 UAH
Glyclazide 30 MV-Indar Glyclazide----
Glyclazide-Gliclazide Lafiya--36 UAH
Glioral Glyclazide----
Diagnizide Gliclazide--14 UAH
Diazide MV Gliclazide--46 UAH
Osliklid Gliclazide--68 UAH
Diadeon gliclazide----
Glyclazide MV Gliclazide4 rub--
Amaril 27 rub4 UAH
Glemaz glimepiride----
Gli karinda--77 UAH
Glimepiride Glyride--149 UAH
Glimepiride diapiride--23 UAH
Alfika --12 UAH
Glimax glimepiride--35 UAH
Glimepiride-Lugal glimepiride--69 UAH
Gwarwar Clay--66 UAH
Diabrex glimepiride--142 UAH
Meglimide glimepiride----
Melpamide Glimepiride--84 UAH
Perinel glimepiride----
Glempid ----
Glimed ----
Glimepiride dabarini27 rub42 UAH
Glimepiride-teva glimepiride--57 UAH
Glimepiride Canon dabarini50 rub--
Glimepiride Magungunan glimepiride----
Dimaril glimepiride--21 UAH
Glamepiride lu'u-lu'u2 rub--
Amaryl M Limepiride Micronized, Metformin Hydrochloride856 rub40 UAH
Glibomet glibenclamide, metformin257 rub101 UAH
Glucovans glibenclamide, metformin34 rub8 UAH
Dianorm-m Glyclazide, Metformin--115 UAH
Dibizid-m glipizide, metformin--30 UAH
Douglimax glimepiride, metformin--44 UAH
Duotrol glibenclamide, metformin----
Gluconorm 45 rub--
Glibofor metformin hydrochloride, glibenclamide--16 UAH
Avandamet ----
Avandaglim ----
Janumet metformin, sitagliptin9 rub1 UAH
Velmetia metformin, sitagliptin6026 rub--
Galvus Met vildagliptin, metformin259 rub1195 UAH
Tripride glimepiride, metformin, pioglitazone--83 UAH
Haɗu da metformin XR, saxagliptin--424 UAH
Comboglyz Prolong metformin, saxagliptin130 rub--
Gentadueto linagliptin, metformin----
Vipdomet metformin, alogliptin55 rub1750 UAH
Sinjardi empagliflozin, metformin hydrochloride240 rub--
Voglibose Oxide--21 UAH
Gzutazone dabari--66 UAH
Dropia Sanovel pioglitazone----
Janavia sitagliptin1369 rub277 UAH
Galvus vildagliptin245 rub895 UAH
Onglisa saxagliptin1472 rub48 UAH
Nesina alogliptin----
Vipidia alogliptin350 rub1250 UAH
Harshen trazhenta linagliptin89 rub1434 UAH
Lixumia lixisenatide--2498 UAH
Guarem guar gum9950 rub24 UAH
Insvada ta sake----
Samurai30 rub90 UAH
Sassan Ranka----
Baeta Exenatide150 rub4600 UAH
Baeta Long Exenatide10248 rub--
Viktoza liraglutide8823 rub2900 UAH
Saxenda liraglutide1374 rub13773 UAH
Forksiga Dapagliflozin--18 UAH
Forsiga Dapagliflozin12 rub3200 UAH
Invocana canagliflozin13 rub3200 UAH
Jardins Empagliflozin222 rub566 UAH
Dulglutide Trulicity115 rub--

Yaya za a iya samun analogue mai tsada na magani mai tsada?

Don neman analog mai rahusawa ga magani, jana'iza ko alaƙa, da farko muna bada shawara a kula da abun da ke ciki, wato ga abubuwa masu aiki iri ɗaya da alamomi don amfani. Abubuwa masu aiki iri ɗaya na maganin zasu nuna cewa miyagun ƙwayoyi suna da alaƙa tare da miyagun ƙwayoyi, daidai da magunguna ko madadin magunguna. Koyaya, kar ka manta game da abubuwanda suka lalace na irin kwayoyi, wanda zai iya shafar aminci da tasiri. Kar ku manta game da umarnin likitoci, magunguna na kai na iya cutar da lafiyar ku, don haka koyaushe tuntuɓi likitanku kafin amfani da kowane magani.

Koyarwar Metfogamma

METFOGAMMA® (METFOGAMMA) Memformin wakilci: WERVAG FARMA GmbH da Co.KG 10 inji mai kwakwalwa. - blister (12) - fakitoci na kwali.

Kwayoyin, farar fata mai rufi, oblong, tare da layin karaya.

Shafin 1 metformin hydrochloride 850 MG

Wadanda suka kware: methylhydroxypropyl cellulose, povidone, magnesium stearate, titanium dioxide (E171), macrogol 6000.

10 inji mai kwakwalwa. - fakiti mai bakin ciki (3) - fakitoci na kwali. 10 inji mai kwakwalwa. - fakiti mai bakin ciki (12) - fakitoci na kwali.

SAURARA №№:

  • shafin. shafi fim, 850 MG: 30 ko 120 inji mai kwakwalwa. - P No 013816 / 01-2002, 03/12/02
  • shafin. shafi fim, 500 MG: 30 ko 120 inji mai kwakwalwa. - P No. 014463 / 01-2002, 10.16.02

Magungunan hypoglycemic na baka daga ƙungiyar biguanide. Yana hana gluconeogenesis a cikin hanta, rage yawan shan glucose daga cikin hanji, haɓaka amfani da keɓaɓɓen glucose, yana kuma ƙara haɓakar jijiyoyin jikin mutum zuwa insulin. Ba ya shafar ɓarin insulin ta sel-cells sel na hanji.

Zazzagewa masu saukarwa, LDL.

Yanke ko rage karfin jiki.

Yana da tasirin fibrinolytic saboda hanawar ƙwaƙwalwar ƙwaƙwalwar ƙwayar plasminogen mai hanawa.

Bayan gudanar da baki, ana amfani da metformin daga ƙwayar narkewa. Bioavailability bayan ɗaukar daidaitaccen kashi shine 50-60%. Cmax bayan maganin baka an sami nasara bayan awa 2.

A zahiri ba a ɗaura shi da sunadaran plasma. Yana tarawa a cikin glandan ciki, tsokoki, hanta, da kodan.

An cire shi baya cikin fitsari. T1 / 2 shine 1,5-4.5 hours.

Pharmacokinetics a cikin lokuta na musamman na asibiti

Tare da nakasa aikin na koda, tarawa daga cikin miyagun ƙwayoyi yana yiwuwa.

- nau'in ciwon sukari na 2 na ciwon sukari (wanda ba shi da insulin-ba) ba tare da sha'awar ketoacidosis (musamman ma a cikin marasa lafiya tare da kiba) tare da rashin lafiyar abinci.

MAGANIN CIKI

Saita daban, yin la'akari da matakin glucose a cikin jini.

Maganin farko na yau da kullun shine 0.5-1 g (Metfogamma 500) ko 850 mg (Metfogamma 850). Furtherarin ƙarin ci gaba na digiri a kan hanya yana yiwuwa gwargwadon tasirin aikin jiyya. Adadin yau da kullun yana tabbatar da 1-2 g (Metfogamma 500) ko 0.85-1.7 g (Metfogamma 850). Matsakaicin adadin yau da kullun shine 3 g (Metfogamma 500) ko 1.7 g (Metfogamma 850). Dalilin maganin a cikin allurai masu girma ba ya kara tasirin magani.

Ana ba da shawarar kowace rana da ta wuce miliya 850 a allurai biyu (safe da yamma).

A cikin marasa lafiya tsofaffi, shawarar da aka ba da shawarar kada ta wuce 850 mg / rana.

Allunan yakamata a ɗauka tare da abinci gaba ɗaya, a wanke da ruwa kaɗan (gilashin ruwa).

Magungunan an yi niyya don amfani na dogon lokaci.

ADDU'AR SAUKI

Daga tsarin narkewa: tashin zuciya, amai, ciwon ciki, zawo, rashin ci, rashin ci, ƙoshin ƙarfe a bakin (a matsayin mai mulkin, ba a buƙatar dakatar da magani, kuma alamu sun ɓace a kan kansu ba tare da canza maganin ba). Za'a iya rage mita da tsananin tasirin sakamako tare da karuwa a hankali a kashi na metformin.

Daga tsarin endocrine: hypoglycemia (lokacin da aka yi amfani dashi a allurai marasa inganci).

Daga gefen metabolism: a lokuta mafi wuya - lactic acidosis (yana buƙatar dakatar da jiyya), tare da tsawaita amfani da - B12 hypovitaminosis (malabsorption).

Daga tsarin hemopoietic: a wasu yanayi - megaloblastic anemia.

Allergic halayen: fatar fata.

KWANKWASIYYA

- mai ciwon sukari ketoacidosis, mai ciwon sukari, coma,

- Cutar rashin lafiyar koda.

- zuciya da rashin numfashi,

- m lokaci na myocardial infarction,

- mummunan hadarin mahalli,

- rashin shan giya na yau da kullun da sauran yanayi waɗanda zasu iya taimakawa ga ci gaban lactic acidosis,

- lactic acidosis da tarihin shi,

- lactation (shayarwa),

- Rashin hankali ga miyagun ƙwayoyi.

Haihuwa da lactation

An sanya miyagun ƙwayoyi don amfani a lokacin daukar ciki da lokacin shayarwa (shayarwa).

LITTAFIN KWARAI

Yin amfani da miyagun ƙwayoyi ba da shawarar ga m cututtuka, da wuce haddi na na kullum cututtuka da kuma mai kumburi, raunin da ya faru, m tiyata cututtuka, lokacin da nuna insulin far.

Ba'a shan magani kafin tiyata kuma cikin kwanaki 2 bayan an yi su.

Ba'a bada shawarar amfani da Metfogamma na akalla kwanaki 2 kafin da kwanaki 2 bayan x-ray ko gwajin rediyo ta amfani da wakilai masu bambanci.

Ba'a ba da shawarar cewa an sanya magunguna ga marasa lafiya akan abinci tare da ƙuntatawa a cikin adadin caloric (ƙasa da 1000 kcal / rana).

Ba'a ba da shawarar yin amfani da miyagun ƙwayoyi a cikin mutanen da suka wuce shekaru 60 da ke yin aikin jiki ba (saboda wannan yana da alaƙa da haɓakar haɗarin lactic acidosis).

A lokacin amfani da miyagun ƙwayoyi, ya kamata a kula da alamun alamun aikin. Akalla sau 2 a shekara, kuma tare da bayyanar myalgia, ya kamata a ƙaddara abubuwan da ke cikin lactate a cikin plasma.

Za'a iya amfani da Metfogamma a hade tare da abubuwan ƙira na sulfonylurea ko insulin, kuma musamman ana buƙatar saka idanu akan matakan glucose na jini.

SAURARA

Bayyanar cututtuka: m lactic acidosis na iya haɓaka. Dalilin ci gaban lactic acidosis kuma na iya zama tarin ƙwayar cutar saboda rauni na aikin keɓaɓɓu. Alamomin farko na lactic acidosis sune tashin zuciya, amai, gudawa, zazzage jiki, zafin ciki, raunin jiki, a nan gaba ana iya samun karuwar numfashi, tsananin farin ciki, rashin nutsuwa da kuma ci gaba.

Jiyya: idan akwai alamun lactic acidosis, magani tare da Metfogamma ya kamata a dakatar da shi nan da nan, ya kamata a kwantar da mai haƙuri cikin gaggawa kuma, tunda ya ƙaddara yawan maganin lactate, tabbatar da cutar. Hemodialysis yana da tasiri sosai don cire lactate da metformin daga jiki. Idan ya cancanta, gudanar da aikin tiyata. Tare da maganin haɗin gwiwa tare da maganin sulfonylureas, hypoglycemia na iya haɓaka.

CIKIN SAUKI

Tare da yin amfani da lokaci ɗaya tare da abubuwan da suka dace na sulfonylurea, acarbose, insulin, NSAIDs, MAO inhibitors, oxygentetracycline, ACE inhibitors, clofibrate, cyclophosphamide, beta-blockers, yana yiwuwa a ƙara tasirin hypoglycemic na metformin.

Tare da yin amfani da lokaci guda tare da GCS, maganin hana haihuwa, epinephrine (adrenaline), sympathomimetics, glucagon, hormones thyroid, thiazide da loopback diuretics, abubuwan asalin phenothiazine, abubuwan nicotinic acid, raguwar sakamako na hypoglycemic na metformin mai yiwuwa ne.

Cimetidine yana rage jinkirin kawar da metformin, wanda ke kara haɗarin lactic acidosis.

Metformin na iya raunana tasirin magungunan anticoagulants (abubuwan da aka samo coumarin).

Tare da gudanarwa na lokaci ɗaya tare da ethanol, haɓakar lactic acidosis mai yiwuwa ne.

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