Glucovans magani ne mai haɓaka da ƙwaƙwalwar ƙwayar cuta, wanda aka kirkira akan tsarin metformin da glibenclamide.

Kamar yadda aka sani, metformin yana cikin rukunin biguanides. Amfani da shi yana taimakawa rage abubuwan glucose a cikin abun da ke ciki. jini jini. A wannan yanayin, babu wani karfafa rufin asiri insulinsaboda haka ba ya inganta yawan haila.

Gabaɗaya, hanyoyin 3 na aiwatarwa sune sifofin metformin, sune:

• raguwa a cikin samarwar glucose ta hanta ta hanyar hana glycogenolysis da gluconeogenesis,
• na kewaye mai karbar insulin ji na jiki, ciwan glucose da kuma amfani da kwayoyin tsoka,
• jinkirta sha daga cikin glucose a cikin narkewa.

Bugu da ƙari, ƙwayar tana da tasiri mai amfani akan abun da ke ciki jinimatakin lowers cholesteroljere triglyceridesda sauransu.

Glibenclamide, wani sinadarin sulfonylurea, ya sami damar rage yawan glucose ta hanyar karfafa kwayar insulin ta sel-cells-sel a cikin hanji.

Kodayake ana amfani da metformin da glibenclamide ta hanyoyi daban-daban na aiwatarwa, amma suna karawa juna karfin jini. A hade, waɗannan wakilan suna nuna ayyukan synergistic a rage abubuwan glucose.

Tare da gudanar da glibenclamide na ciki, ɗaukar shi a cikin ƙwayar gastrointestinal aƙalla 95%. Wannan abu mai micronized. Nasarar mafi girman maida hankali a cikin plasma an cimma shi cikin sa'o'i 4. Yin jingina ga furotin plasma yayi daidai da 99%. Sakamakon haka metabolism 2 m ne a cikin hanta metaboliteexcreted da kodan da bile.

Ana nuna Metformin ta cikakkiyar ɗauka daga ƙwayar gastrointestinal, tare da kaiwa matsakaicin natsuwa bayan sa'o'i 2.5. Abinda ke cikin matsanancin rauni. A lokaci guda, sashinsa an cire shi da taimakon kodan.

Haɗin metformin da glibenclamide suna da daidai iri ɗaya kamar abubuwan abubuwa dabam. Cin abinci baya tasiri bioavailability na metformin, amma yana ƙaruwa da ƙima na glibenclamide.

Alamu don amfani

Alamar shan kwayoyin ita ce nau'in ciwon sukari na 2 a cikin manya marasa lafiya:

• ba tare da tasiri ba abinci, motsa jiki da magani na baya tare da metformin,
• domin maye gurbin magani na baya ga marasa lafiya waɗanda a cikinsu ana sarrafa matakin glycemia.

Contraindications

Ba a ba da shawarar maganin ba don:

• ji na ƙwarai a gare shi da abun da ke ciki,
• nau'in ciwon sukari
• na gazawar da cutar koda,
• mai ciwon sukari ketoacidosis, precomda coma
• matsanancin yanayi wanda ke haifar da canje-canje a aikin koda: bushewar jiki, cututtuka masu zafi, girgiza da sauransu,
• m ko m cututtuka tare da nama hypoxia: zuciya ko na numfashi kasa, baya infarction na zuciyajihar bugawa
• yara
• gazawar hanta
• porfria
• lactation, ciki,
• babban tiyata
• na kullum mai shan barasa ko rashin sa maye maye,
• lactic acidosis,
• biye da tsarin karancin kalori.

Bugu da kari, ba a ba da shawarar maganin ga marasa lafiya wadanda suka haura shekaru 60, mutane suna yin aiki tuƙuru kuma suna da cututtukan cututtukan da ba a taɓa sani ba da ke da alaƙa da ƙwaƙwalwar galactose, gubar glucose-galactose malabsorption syndrome da kuma rashi lactase.

Dole ne a yi taka tsantsan wajen lura da marasa lafiya da cututtukan febrile, ƙarancin adrenal, hypofunction na farji na huhun ciki, cututtukan thyroid, da sauran rikice-rikice.

Side effects

Lokacin yin jiyya tare da Glucovans, sakamako masu illa suna shafar yawancin gabobin da tsarin jiki.

Rashin daidaituwa na metabolism zai iya kasancewa tare da hypoglycemia, harin hepatic ko cutaneous porphyria, lactic acidosis, da sauransu.

Tsarin wurare dabam dabam da jijiyoyin jini suna iya amsawa leukopenia, thrombocytopenia, agranulocytosiswanda yawanci yakan wuce bayan janyewar magunguna.

Sakamakon sakamako wanda ya shafi aikin jijiya shine keta dandano. Har ila yau, ba a cire taɗuwa cikin ayyukan gabobin hangen nesa ba, ƙwayar gastrointestinal, fata da ƙarancin nama.

Abubuwan da ke tattare da rikice-rikice na rigakafi, rikice-rikice na hepatobiliary da canje-canje a cikin sigogi na dakin gwaje-gwaje, alal misali, haɓakar taro, na iya faruwa wasu lokuta urea creatinineci gabahyponatremia.

Umarnin don amfanin Glucovans (Hanyar da sashi)

Wannan wakilin hypoglycemic an yi shi ne don gudanar da maganin baka. A wannan yanayin, umarnin don amfani da Glucovans ya ba da rahoton cewa an ƙayyade adadin maganin a cikin daban-daban ga kowane yanayi kuma ya dogara da matakin glycemia.

Fara magani tare da kwamfutar hannu guda don yawan maganin yau da kullun. Don hana haɓakar haɓakar hypoglycemia, ya zama dole cewa farkon matakin bai wuce yawan maganin yau da kullun na glibenclamide ko metformin ba, waɗanda aka yi amfani dasu a da. Sabili da haka, zaku iya haɓaka kashi kawai ta 5 MG + 500 MG kowace rana a duk sati 2 ko fiye. Wannan hanyar tana ba ku damar samun isasshen iko na matakan glucose na jini.

Don maye gurbin maganin da aka haɗo na baya tare da metformin da glibenclamide, an saita kashi na farko daidai da ƙimar da aka karɓa a baya. Duk sati 2 ko fiye da farawa daga farawa, ana iya daidaita sikelin gwargwadon matakin ƙwayar cuta.

A wannan yanayin, matsakaicin adadin yau da kullun shine allunan 4 Glucovans 5 + 500 MG ko 6 a 2.5 + 500 MG. Maganin warkewa ya dogara da shawarar mutum na kwararrun.

Allunan ya kamata a dauka tare da abinci. Yana da mahimmanci cewa kowane amfani da miyagun ƙwayoyi yana haɗuwa tare da amfani da abinci mai narkewa a cikin carbohydrates, wanda ke taimakawa hana faruwar cututtukan jini.

Yawan abin sama da ya kamata

A cikin yanayin yawan zubar da jini, ƙwanƙwasa jini na iya haɓaka. Don bayyanar mai sauƙin zuwa matsakaici, ana iya samun daidaituwa ta hanyar amfani da sukari nan da nan. Amma kuna buƙatar gaggawa da daidaita sashi da rage cin abinci.

Reactionsarancin cututtukan da ake kira hypoglycemic, tare da coma, paroxysm, wasu rikicewar jijiyoyin jini, suna buƙatar kulawar likita ta gaggawa.

Muhimmin jiyya ya haɗa da allurar mafita zuwa jijiya. Dextroseda sauran hanyoyin kwantar da hankali. Lokacin da aka dawo da hankali, ya kamata a ciyar da mai haƙuri a cikin abinci mai narkewa mai sauƙin narkewa mai narkewa, wanda zai guje wa sake farfadowa da ƙwanƙwasa jini.

Bugu da kari, ci gaban lactic acidosis, magani wanda aka yi a asibiti, ba a cire shi ba. Wani ingantaccen magani wanda ke taimakawa cire metformin da lactate maganin hemodialysis.

Haɗa kai

Shan wannan magani tare da Miconazole na iya haifar da ci gaban hypoglycemia saboda abubuwan da ke cikin glibenclamide. An hana amfani da lokaci daya tare da waken masu bambancin aidin.

Fankamara sami damar haɓaka tasirin cutar ƙwayar cuta. Haɗin kai tare da Bosentan.

Yayin amfani da wannan kayan aiki, ana bada shawara don ɗauka da taka tsantsan Chlorpromazine, Tetracosactide, Danazole,β2-adrenergic agonists, diuretics, wasu inhibitors na ACE waɗanda zasu iya canza abubuwan glucose a cikin jini kuma suna haifar da haɓaka tasirin da ba'a so. Sabili da haka, shan kowane magani yana buƙatar shawarar m na gwani.

Glucovans analogues

Babban analogues:Glybomet, Glucofast, Metformin da Siofor.

Yin amfani da barasa a lokaci guda na iya haifar da haɓakar lactic acidosis, wanda zai iya haɓaka tare da mummunan maye giya. Ana cutar da yanayin ta dalilin yunwar ko abinci mara kyau, haka kuma gazawar hanta. Bugu da kari, barasa galibi yana haifar da cututtukan jini. Don haka, dole ne a nisantar amfani da giya da sauran kayayyakin da ke dauke da giya.

Nazarin Glucovans

Tattaunawa game da wannan kayan aiki ana samun su sau da yawa a kan mahaɗan da ke da alaƙa da ciwon sukari. Marasa lafiya waɗanda aka wajabta wannan magani sau da yawa suna tattauna tambayoyi game da zaɓi na makirci da sashi, kazalika da haɗin gwiwa tare da magunguna daban-daban. A lokaci guda, sake dubawa game da Glucovans 5 + 500 MG da 2.5 + 500 MG sune mafi yawan rigima. Yawancin lokaci, don cimma tasiri, ya zama dole a lura da adadin adadin kuzari da carbohydrates ke ci kuma, hakika, sashi na magunguna.

Abin takaici, wasu lokuta akwai sake dubawa cewa shan wannan magani ba ya kawo sauƙin. Misali, a wasu majinyaci, akwai rashin aiki a matakin sukari a cikin jini, wato hypoglycemia. Sauran marasa lafiya sun ba da rahoton cewa don daidaita lafiyar su, sun buƙaci tsayayyen daidaitaccen tsarin rayuwarsu da tsarin kulawa.

Koyaya, magunguna irin wannan suna da mahimmanci musamman ga aikin likita, saboda suna inganta yanayin rayuwar marasa lafiya masu ciwon sukari. Irin wannan binciken yana nuna cewa lafiyar mai haƙuri koyaushe yana buƙatar sarrafawa da magani na musamman. Wannan zai yiwu ne kawai ga haɗin gwiwa na likitan da haƙuri, wanda ke haifar da ingantattun ci gaba a cikin yanayin.

Abun ciki, tsarin aiki da alamomi don amfani

Glucovans magani ne wanda babban abubuwan aikinsa sune metformin da glibenclamide. Ya kasance cikin rukuni na haɗakar magungunan hypoglycemic waɗanda aka haɓaka don amfani a matsayin ɓangaren ɓangaren hadaddun hanyoyin kwantar da hankali ga mutanen da ke fama da ciwon sukari na mutum na biyu (nau'in cututtukan da ba a dogara da su ba). Fitowa mai saki - Allunan don maganin baka. Kunshin ya ƙunshi blister biyu ko huɗu, kowannensu yana dauke da allunan 10 ko 15. Dangane da adadin allunan a cikin kunshin, farashin ya bambanta daga 280 zuwa 400 rubles.

Za'a iya bayyana mizanin aikin miyagun ƙwayoyi a cikin kalmomi masu sauƙi: lokacin ɗauka tare da abinci, yana taimakawa ragewa ko kuma ɗaukar wani abu a cikin carbohydrates, sakamakon wanda ba a yarda da jijiyoyin baƙi a cikin jini. Babban aiki na metformin na miyagun ƙwayoyi an haɗa shi a cikin rukunin magungunan biguanides, kamar yadda umarnin ya tabbatar. Glucovans analogues suna da tasiri saboda abu guda. Sabili da haka, yana da ma'ana don yin gwaji tare da zaɓi don kanku na magani mai dacewa daga nau'in farashin mai rahusa, amma tare da kayan haɗin guda ɗaya a cikin abun da ke ciki.

Don metformin (wanda shine babban sinadari mai amfani kuma ga yawancin analogues na Glucovans), ka'idodi uku na bayyanuwa ga jiki sune halayyar:

• rage kiba na samarda glucose din hanji ta hanyar hana glycogenolysis da gluconeogenesis,
• na kewaye mai karbar insulin ji na jiki, ciwan glucose da kuma amfani da kwayoyin tsoka,
• jinkirta sha daga cikin glucose a cikin narkewa.

Sakamakon wannan tasirin rikicewar, ƙwayar ta tabbatar da kanta a cikin lura da nau'in ciwon sukari na type 2 - duka biyu azaman kayan aiki mai zaman kanta kuma a matsayin mai tallafawa jiyya (yana yiwuwa a yi amfani da shi a layi ɗaya tare da wasu kwayoyi, bitamin da kayan abinci bayan amincewar hanya ta hanyar magani ta halartar endocrinologist).

Nau'in 1 da nau'in ciwon sukari na 2

Ciwon sukari mellitus shine ainihin "annoba" na lokacinmu. Endocrinologists suna sautin kararrawa: a cikin 'yan shekarun nan, maganganun nau'in insulin-dogara da ciwon sukari mellitus sun zama mafi yawan lokuta tsakanin matasa. Kimanin shekaru hamsin da suka wuce, an gano wannan cuta, a matsayin mai mulkin, kawai a cikin mutane (galibi mata) waɗanda suka girmi shekaru 50. A mafi yawan lokuta, sanadin ci gabanta shine rashin abinci mai kyau na shekaru da yawa, rashin aikin farji, mummunan tashin hankali da damuwa na tsawon lokaci.

Yana da ma'ana don amfani da miyagun ƙwayoyi idan mara lafiya bai karɓi insulin ta allura ba. Babu damuwa ko mutumin da ke fama da ciwon sukari ya yarda da abincin maras nauyi na musamman ko a'a, Glucovans 5500 da analogues tare da adadin adadin metformin a cikin abun da ke ciki tare da cin abinci na yau da kullun zai ba da damar cimma ƙarancin sha na carbohydrates. Tabbas, shan irin waɗannan magungunan ba ƙaramin abu bane a cikin izini dangane da abinci. Ko da a kan asalin tsarin ilimin magunguna, dole ne mai haƙuri ya bi ka'idodin abinci mai ƙarancin-carb. Koyaya, endocrinologists yawanci suna gargaɗin marasa lafiyarsu cewa analogues na Glucovans tare da metformin a cikin abun da ke ciki ya sa ya yiwu a bi cin abincin sosai, ba tare da tsoron sakamakon rashin ƙoshin lafiya da kwatsam ba a cikin sukari. Amma kada ku dogara da yawa kan tasirin kwayoyi - adadin carbohydrates da aka cinye tare da abinci dole ne a rage shi a kowane yanayi.

Contraindications da shawarar sashi

Jagorar don yin amfani da rahoto tana cewa akwai abubuwan da ke biyo baya don ɗaukar allunan Glucovans:

• nau'in ciwon sukari guda 1
• na kullum na koda da sauran pathologies na kodan (nephrologist shawara da ake bukata),
• ciki, lactation,
• lokacin murmurewa bayan tiyata,
• na kullum barasa, lokacin shan giya,
• bushewa, lokacin tsananin cututtuka,
• cututtukan hanta na hanta (liyafar ta yiwu bayan tattaunawa tare da masanin ilimin hepatologist).

Glucovans 500 da analogues na wannan miyagun ƙwayoyi suna shafar shaye-shayen carbohydrates, sabili da haka, har ma tare da kashi ɗaya, zasu iya tayar da hankali a cikin marasa lafiya tare da cututtukan hanta da koda. Gudanar da kai na miyagun ƙwayoyi ba zai yiwu ba - duk da gaskiyar cewa ana siyar da shi ba tare da takardar sayan magani ba kuma kowa zai iya siyan sa, ya kamata a fara bincika gabobin ciki kafin a sha shi kuma a tabbatar da tuntuɓar likitan ilimin dabbobi. Sau da yawa ba shi da sauƙi don gano sashi don dacewa da haƙuri - kwamfutar hannu guda ɗaya a rana ya isa ga mutum, kuma uku ba zai isa mutum ba. Mafi kyawun sashi ya dogara da halaye na jikin mutum - nauyi, jinsi, shekaru, sakamakon gwajin jini.

Jerin analogues ta tsarin aiki

Analogues da madadin magungunan "Glucovans", wanda ya ƙunshi metformin a matsayin babban aiki mai aiki:

• Karin Galvus,
• Siofor
• Glucophage,
• Glibomet,
• Gluconorm,
• Amaril M

Duk waɗannan magunguna suna da ƙa'idar aiki guda ɗaya - suna rage shaƙar carbohydrates, saboda haƙuri ya fara jin daɗi, sha'awar carbohydrates mai sauƙi yana raguwa, yana zama mafi sauƙi don ci gaba da rage cin abinci, kuma matakan sukari na jini suna daidaita al'ada.

Mafi ƙarancin analog na allunan Glucovans shine Metformin. Koyaya, a cikin kantin magunguna yana da matukar wuya a sami. Ko da akwai, masana harhada magunguna sun gwammace su bayar da ƙarin magunguna masu tsada.

Metv Galvus: umarnin don amfani da sake dubawa akan kwatankwacin alamar Glucovans

Farashin miyagun ƙwayoyi ya kusan 1300 rubles a kowane fakitin. Galvus Met ya fi tsada saboda, ban da metformin, an kuma haɗa vildagliptin. Waɗannan abubuwan haɗin jini guda biyu ne waɗanda ke da tasiri dabam dabam. Musamman, vildagliptin shine dipeptidyl peptidase-4 inhibitor. Tare da metformin, wannan sinadarin yana haifar da raguwar raguwa a cikin taro na glucose. Yawancin marasa lafiya da ke da nau'in ciwon sukari na 2 suna buƙatar shan kwamfutar hannu guda ɗaya kawai a rana, yayin da Glucovans ya kamata a sha sau da yawa a rana.

Sabili da haka, babban farashin ya barata: a sakamakon haka, hanyar Galvus Met ta fi tattalin arziki yawanci fiye da hanyar Glucovans. Binciken game da kayan aiki "Galvus Met" ya sha bamban. Yawancin ya dogara da yadda mutum ya bi abin da ake ci. Yawancin sake dubawa har yanzu suna da kyau: marasa lafiya suna jaddada cewa, saboda godiya ga yawan magunguna, sun sami damar dawo da matakan glucose na jini na yau da kullun. Yana da, ba shakka, a mafi yawan lokuta an ɗaukaka shi, amma kwanciyar hankali, sakamakon abin da marasa lafiya ke jin daɗin jin daɗi, ingantaccen aiki kuma ba sa fama da ƙoshi, tashin zuciya da sauran alamun cutar.

Bayanin sigar sashi

Sashi 2.5 mg +500 mg: Allunan biconvex mai kwalliya, mai hade da murfin fim na launin ruwan orange, tare da zanen “2.5” a gefe guda.

Sashi 5 MG +500 MG: Allunan biconvex mai kwalliya, mai hade da launin rawaya fim, tare da zane "5" a gefe guda.

Pharmacokinetics

Glibenclamide. Lokacin gudanar da shi, sha daga ƙwayar gastrointestinal ya fi 95%. Glibenclamide, wanda shine ɓangare na miyagun ƙwayoyi Glucovans is, micronized ne. C_max a cikin plasma an kai shi a cikin awanni 4, V_d - kimanin lita 10. Sadarwa tare da sunadaran plasma kashi 99%. An kusan kusan metabolized a cikin hanta tare da samuwar metabolites guda biyu marasa aiki, wadanda kodan ke cirewa (40%) kuma da bile (60%). T_1/2 - daga 4 zuwa 11 hours

Metformin. Bayan gudanar da baki, an amshi shi daga narkewa kamar jijiyoyi, C_max a cikin plasma an cimma shi cikin awa 2.5. Kimanin 20-30% na metformin an keɓance ta ta cikin jijiyoyi a cikin hanyar da ba'a canza su ba. Cikakken bayanin halitta daga 50 zuwa 60%. An rarraba Metformin cikin hanzari a cikin kyallen takarda, kusan ba a ɗaura shi ga furotin plasma ba. Yana cikin metabolized sosai ga rauni sosai kuma kodan ya keɓe shi. T_1/2 matsakaita na awanni 6.5. Idan akwai matsalar aiki na keɓaɓɓiyar aiki, toshewar koda yake raguwa, haka ma keɓantaccen ɗaukar hoto, yayin da T_1/2 yana ƙaruwa, wanda ke haifar da haɓakar haɗarin metformin a cikin jini na jini.

Haɗin metformin da glibenclamide a cikin tsari iri ɗaya suna da daidai iri ɗaya kamar lokacin ɗaukar allunan da ke ɗauke da metformin ko glibenclamide a cikin keɓance. Rashin abinci na metformin a hade tare da glibenclamide ba shi da matsala ta hanyar abinci, kazalika da bioavailability na glibenclamide. Koyaya, yawan shan glibenclamide yana ƙaruwa tare da ɗimbin abinci.

Alamun magungunan Glukovans ®

Type 2 ciwon sukari a cikin manya:

- tare da rashin ingancin maganin motsa jiki, motsa jiki da warkarwa na baya tare da abubuwan da suka dace da tsarin metformin ko abubuwan da suka samo asali na sulfonylurea,

- don maye gurbin maganin da ya gabata tare da kwayoyi guda biyu (metformin da mai maganin sulfonylurea) a cikin marasa lafiya tare da tsayayyen tsari mai kyau na glycemia.

Haihuwa da lactation

Yin amfani da maganin yana contraindicated lokacin daukar ciki. Yakamata a gargadi mara lafiya cewa a lokacin jiyya tare da miyagun ƙwayoyi Glucovans is ya zama dole a sanar da likita game da shirin da aka shirya da farawar ciki. Lokacin da ake shirin yin ciki, da kuma lokacin da ake yin ciki yayin lokacin shan Glucovans ®, yakamata a soke maganin kuma an sanya masa maganin insulin.

Glucovans ® yana cikin garkuwar nono, domin babu wata hujja game da iyawarta ta shiga cikin madara.

Side effects

Abubuwanda zasu biyo baya na iya faruwa yayin magani tare da Glucovans ®: Ana kiyasta yawan tasirin sakamako na miyagun ƙwayoyi kamar haka: akai-akai - ≥1 / 10, akai-akai - ≥1 / 100, ƙwayar gastrointestinal: sau da yawa sosai - tashin zuciya, amai, zawo, ciwon ciki da rashin ci. Wadannan bayyanar cututtuka sun fi yawa a farkon magani kuma a mafi yawan lokuta suna ba da nasu. Don hana ci gaban waɗannan bayyanar cututtuka, ana bada shawara don ɗaukar ƙwayar a cikin allurai 2 ko 3, jinkirin karuwa a cikin adadin maganin yana inganta haƙurinsa.

A bangare na fata da kasusuwa na jiki: da wuya, halayen fata, irin su itching, urticaria, maculopapular fyaɗe, da wuya, fata ko visceral rashin lafiyar vasculitis, polymorphic erythema, exfoliative dermatitis, photoensitivity.

Abubuwan da ba a fahimta ba: da wuya sosai - girgiza anaphylactic. Abubuwan da ke haifar da tasirin jini ga abubuwan sulfonamides da abubuwan da zasu iya haifarwa na iya faruwa.

Rashin lafiyar Hepatobiliary: da wuya - alamomin aikin hanta masu rauni ko cutar hepatitis, da ke buƙatar dakatar da magani.

Umarni na musamman

A kan tushen jiyya tare da Glucovans ®, Ya wajaba don saka idanu akan matakan glucose mai azumi da kuma bayan cin abinci.

Lactic acidosis abu ne mai matukar wahala amma mai muni (babban mace-mace a cikin rashin magani na gaggawa) rikitarwa wanda zai iya faruwa saboda tarin metformin. Cases na lactic acidosis a cikin marasa lafiya da aka bi da metformin ya faru a cikin mafi yawan marasa lafiya da ciwon sukari mellitus tare da gazawar na koda.

Sauran abubuwan haɗari masu haɗari yakamata ayi la'akari dasu, irin su ciwon sukari mara ƙarfi, ketosis, tsawan azumi, yawan shan giya, gazawar hanta, da duk wani yanayin da yake da alaƙa da cutar hypoxia.

Ya kamata kuyi la'akari da haɗarin lactic acidosis tare da bayyanar alamun rashin daidaituwa, irin su murƙushe ƙwayar tsoka, tare da raunin dyspeptik, ciwon ciki da zazzabin cizon sauro. A cikin mawuyacin hali, rauni na acidotic na numfashi, hypoxia, hypothermia, da coma na iya faruwa.

Sigogin gwaje-gwaje na bincike sune: ƙarancin pH na jini, maida hankali na lactate plasma sama da 5 mmol / l, haɓaka tazara tsakanin anionic da lactate / pyruvate rabo.

Tunda Glucovans ® ya ƙunshi glibenclamide, shan miyagun ƙwayoyi yana haɗuwa da haɗarin hypoglycemia a cikin haƙuri. Titin hankali na kashi na kashi bayan farkon jiyya na iya hana faruwar cututtukan jini. Za'a iya tsara wannan magani ne kawai ga mara lafiyar da ke bin abincin yau da kullun (gami da karin kumallo). Yana da mahimmanci cewa yawan abin da ke cikin ƙwayar carbohydrate shine na yau da kullun, saboda haɗarin haɓakar hauhawar jini yana ƙaruwa tare da abincin da ya dace, da isasshen abinci ko rashin daidaituwa. Haɓaka haɗarin hypoglycemia ya fi dacewa tare da rage yawan hypocaloric, bayan tsananin aiki ko tsawanta a jiki, tare da giya ko tare da haɗin gabobin ƙwayoyin cuta.

Sakamakon halayen rama wanda hypoglycemia ya haifar, gumi, tsoro, tachycardia, hauhawar jini, cututtukan fata, angina pectoris da arrhythmia na iya faruwa. Alamar ta ƙarshe zata iya kasancewa idan ba hypoglycemia haɓaka sannu a hankali ba, a cikin yanayin neuropathy na autonomic ko yayin shan β-blockers, clonidine, reserpine, guanethidine ko sympathomimetics.

Sauran alamun cututtukan hypoglycemia a cikin marasa lafiya da ciwon sukari na iya haɗawa da ciwon kai, yunwa, tashin zuciya, amai, gajiya mai yawa, tashin hankali, tashin hankali, tsokanar hankali, rashin hankalin da halayen psychomotor, ɓacin rai, rikicewa, rashi magana, hangen nesa, rawar jiki, matsewa. da kuma paresthesia, tsananin farji, farji, rashi, shakku, rashin sani, numfashi mara nauyi, da bradycardia.

Cribididdigar kulawa da hankali, zaɓin kashi, da kuma umarnin da ya dace don haƙuri yana da mahimmanci don rage haɗarin cutar hypoglycemia. Idan mai haƙuri ya tuna da hare-haren hypoglycemia, waɗanda suke ko dai mai tsanani ko kuma ke da alaƙa da jahilcin alamu, ya kamata a ba da kulawa ga wasu likitocin da ke ɗauke da cutar.

Abubuwan da ke ba da gudummawa ga ci gaban hawan jini:

- amfani da giya a lokaci daya, musamman yayin azumi,

- ƙi ko (musamman ga tsofaffi marasa lafiya) rashin ikon haƙuri don yin hulɗa tare da likita kuma bi shawarwarin da aka shimfida a cikin umarnin don amfani,

- ƙarancin abinci mai gina jiki, rashin abinci na yau da kullun, yunwar ko canje-canje a abinci,

- rashin daidaituwa a tsakanin motsa jiki da kuma yawan ƙwayar carbohydrate,

mai tsanani hanta

- yawan shan kwayoyi na Glukovans ®,

- rikicewar mutum na endocrine: karancin ƙwayar thyroid, glandon ƙwayar ciki da glandar adrenal,

- Gudanarwa na lokaci daya na kwayoyi.

Renal da hanta ta gaza

Pharmacokinetics da / ko pharmacodynamics na iya bambanta a cikin marasa lafiya tare da raunin hepatic ko raunin renal mai rauni. Rashin lafiyar hypoglycemia wanda ke faruwa a cikin irin waɗannan marasa lafiya na iya tsawaita, a cikin wannan yanayin ya kamata a fara kulawa da ta dace.

Rashin Tsarin Glucose na jini

Idan ana maganar tiyata ko wani dalilin lalata cuta, ana bada shawarar yin lamuran wucin gadi zuwa insulin therapy. Bayyanar cututtukan hyperglycemia sune urination akai-akai, tsananin kishirwa, bushewar fata.

48 hours kafin aikin tiyata ko allurar iv na wakilin rediyo wanda ke dauke da sinadarin ioine, yakamata a daina maganin Glucovans.. An yaba bada magani don sake farawa bayan sa'o'i 48 kuma sai bayan an tantance aikin na asali ne kuma an gane shi al'ada.

Tunda metformin ya cire kodan, kafin fara magani kuma a kai a kai, ya zama dole a tantance Cl creatinine da / ko serin creatinine: a kalla sau daya a shekara a cikin marasa lafiya da ke da aikin na al'ada, kuma sau 2 a shekara a cikin tsofaffi marassa lafiya, da Hakanan a cikin marasa lafiya tare da Cl creatinine akan VGN.

An ba da shawarar yin karin kulawa a lokuta idan aikin mai rauni zai lalace, alal misali, a cikin tsofaffi marasa lafiya ko a cikin yanayin farawa na antihypertensive therapy, diuretics ko NSAIDs.

Sauran kiyayewa

Mai haƙuri dole ne ya sanar da likita game da bayyanar kamuwa da cututtukan bronchopulmonary ko wata cuta mai rarrafe ta gabobin ƙwayoyin cuta.

Tasiri kan iya tuƙin mota da aiki tare da kayan aiki. Yakamata a sanar da mara lafiyar game da hadarin cututtukan hypoglycemia da lura da taka tsantsan yayin tuki da aiki tare da hanyoyin da ke bukatar karuwar hankali da saurin halayen psychomotor.

Mai masana'anta

Adireshin doka: 37, rue Saint-Romaine, 69379, LION SEDEX, 08, Faransa.

Adireshin wurin samarwa: Center de Producion CEMOIS, 2, rue du Pressoir Ver, 45400, CEMOIS, Faransa.

Da'awar Abokan Ciniki da bayani game da mummunan lamari yakamata a aika zuwa adireshin LLC Merk: 115054, Moscow, ul. Gashi, 35.

Waya: (495) 937-33-04, (495) 937-33-05.

Hada magungunan ƙwayar cuta ta Glucovans: farashi, analogues da umarnin amfani

Glucovans magani ne mai hadewar cututtukan jini.

An yi nufin amfani dashi ne na ciki.

Magungunan yana da tasiri mai kyau a cikin ƙwayar lipid na jini, bayan aikace-aikacen, rage yawan adadin ƙwayoyin cholesterol.

Fom ɗin saki

Kwalalin Glucovans an lullube su da wani fim mai nau'in membrane mai haske mai launi mai haske, suna da kamannin kamannin (biconvex).

Glucovans Allunan 500 MG

A gefe ɗaya na kowane kwamfutar hannu zaka iya ganin zane "2.5" ko "5" (abubuwan da ke cikin glibenclamide a cikin MG a cikin kwamfutar hannu ɗaya). Packaya daga cikin fakitin ya ƙunshi allunan 2 ko 4. Harafin “M (wajibi ne don kariya daga bugawa) alama ce a jikin kwali da kuma tambarin filastik.

Bayanin maganin

Glucovans - Hada magunguna na hypoglycemic don amfani da baka.

Glucovans ® wani hadadden haɗuwa ne na wakilai na jini guda biyu na ƙungiyoyin magunguna daban-daban: metformin da glibenclamide.

Metformin yana cikin rukunin biguanides kuma yana rage yawan abubuwan glual da na postprandial a cikin jini. Metformin baya motsa insulin insulin kuma sabili da haka baya haifar da ƙwanƙwasa jini. Yana da matakai 3 na aikin:

- yana rage haɓakar glucose ta hanta ta hana gluconeogenesis da glycogenolysis,

- yana haɓaka hankalin masu karɓar nai zuwa insulin, yawan amfani da amfani da glucose ta sel a cikin tsokoki,

- yana jinkirta ɗaukar glucose daga narkewar abinci.

Hakanan yana da amfani mai amfani a cikin abubuwan da ke tattare da rage yawan jini, rage matakin adadin cholesterol, LDL da TG.

Metformin da glibenclamide suna da matakai daban-daban na aiwatarwa, amma tare da jituwa tare da juna kan ayyukan hypoglycemic. Haɗin haɗakar abubuwa biyu na jini yana da tasirin aiki don rage glucose.

Baƙi 23 sun ba da rahoton yawan cin abincin yau da kullun