Thioctacid - capsules, allunan
Thioctacid BV: umarnin don amfani da bita
Sunan Latin: Thioctacid
Lambar ATX: A16AX01
Abunda yake aiki: thioctic acid (thioctic acid)
Mai samarwa: GmbH MEDA Manufacturing (Jamus)
Ofaukaka bayanin da hoto: 10.24.2018
Farashin kuɗi a cikin kantin magani: daga 1599 rubles.
Thioctacid BV magani ne na rayuwa tare da tasirin antioxidant.
Formaddamar da tsari da abun da ke ciki
Thioctacid BV yana samuwa a cikin nau'ikan Allunan, mai rufin fim: kore-rawaya, oblong biconvex (30, 60 ko 100 inji. A cikin kwalaben gilashin duhu, kwalban 1 a cikin kwali na kwali).
Kwamfutar hannu 1 ya ƙunshi:
- abu mai aiki: thioctic (alpha-lipoic) acid - 0.6 g,
- karin abubuwan taimako: magnesium stearate, hyprolose, low-sauya hyprolose,
- Abun shafi fim: titanium dioxide, macrogol 6000, hypromellose, aluminium varnish dangane da indigo carmine da fenti quinoline rawaya, talc.
Aikin magunguna
Coenzyme wanda ke da hannu a cikin yankewar ƙwayar oxidative na pyruvic acid da alpha-keto acid suna taka muhimmiyar rawa a ma'aunin makamashi na jiki. Ta hanyar dabi'ar biochemical, lipoic acid yana kama da bitamin B. Yana halartar tsari na lipid da carbohydrate metabolism, yana da tasirin lipotropic, yana tasiri metabolism, inganta aikin hanta, yana da tasirin detoxifying idan ya kasance mai guba tare da baƙin ƙarfe na baƙin ƙarfe da sauran maye.
Haɗa kai
Magungunan yana haɓaka tasirin rigakafin cutar corticosteroids.
Tare da amfani na lokaci daya, an lura da raguwar tasiri na cisplatin. Wadannan kwayoyi suna ɗaukar karafa, don haka bai kamata a tsara musu su a lokaci ɗaya tare da kwayoyi waɗanda ke ɗauke da karafa ba (misali, baƙin ƙarfe, magnesium, alli da ke ƙunshe da kayan kiwo).
Tare da yin amfani da lokaci ɗaya, aikin insulin da magungunan antidiabetic don gudanar da baki yana iya haɓakawa, sabili da haka, ana bada shawarar kulawa da matakan yau da kullun na glucose jini, musamman a farkon farawar magani. A cikin wasu halaye, yana yiwuwa a rage kashi na magungunan hypoglycemic don guje wa ci gaban bayyanar cututtuka na hypoglycemia (ƙarancin glucose na jini).
Idan an dauki mintuna 30 kafin karin kumallo, to za a iya ɗaukan shirye-shiryen da ke ɗauke da baƙin ƙarfe ko magnesium da yamma ko da yamma.
Barasa na iya rage tasirin maganin. Saboda haka, an shawarci marasa lafiya da su guji shan giya yayin magani tare da miyagun ƙwayoyi.
Pharmacodynamics
Thioctacid BV magani ne na rayuwa wanda ke inganta jijiyoyin trophic, yana da hepatoprotective, hypocholesterolemic, hypoglycemic, da kuma tasirin rage kiba.
Aiki mai guba na miyagun ƙwayoyi shine thioctic acid, wanda yake a cikin jikin mutum kuma shine maganin antioxidant mai karewa. A matsayin coenzyme, yana shiga cikin isharar oxidative phosphorylation na pyruvic acid da alpha-keto acid. Hanyar aiki na thioctic acid yana kusa da tasirin biochemical na bitamin B Yana taimakawa kare sel daga cutarwa mai guba waɗanda ke faruwa a cikin matakan metabolism, kuma yana kawar da ƙwayoyin guba mai guba waɗanda suka shiga cikin jiki. Theara matakin antinoidid glutathione, yana haifar da raguwa cikin tsananin alamun cutar polyneuropathy.
Tasirin rikodin maganin thioctic acid da insulin shine karuwa a amfani da glucose.
Pharmacokinetics
Rashin maganin thioctic acid daga gastrointestinal fili (GIT) lokacin da ake sarrafa shi a baki yana faruwa da sauri kuma gaba daya. Shan maganin tare da abinci na iya rage shashi. Cmax (mafi girman hankali) a cikin jini (plasma) jini bayan shan guda daya ana samunsa ne bayan mintina 30 kuma shine 0.004 mg / ml. Ainihin bioavailability na Thioctacid BV shine kashi 20%.
Kafin shiga cikin wurare dabam dabam na jini, acid thioctic acid yana ɗaukar sakamakon jijiyar farko ta hanta. Babban hanyoyin da ake aiki da shi shine hadawan abu da iskar shaka.
T1/2 (rabin rai) minti 25 ne.
Fitar da sinadaran aiki Thioctacid BV da metabolites dinsu suna gudana ne ta hanjin kodan. Tare da fitsari, kashi 80-90% na maganin yana warwatse.
Umarnin don amfani da Thioctacid BV: hanya da sashi
Dangane da umarnin, an dauki Thioctacid BV 600 MG a kan komai a ciki, awanni 0.5 kafin karin kumallo, hadiye duka da shan ruwa mai yawa.
Shawarar da aka ba da shawarar: 1 pc. Sau ɗaya a rana.
Ganin yiwuwar asibiti, don lura da mummunan siffofin polyneuropathy, gudanarwa na farko na mafita na maganin thioctic don gudanarwar cikin jini (Thioctacid 600 T) na tsawon kwanaki 14 zuwa 28 yana yiwuwa, biye da mai haƙuri zuwa ci gaba na yau da kullum na miyagun ƙwayoyi (Thioctacid BV).
Side effects
- daga tsarin narkewa: sau da yawa - tashin zuciya, da wuya - amai, jin zafi a ciki da hanji, gudawa, take hakkin dandano,
- daga tsarin juyayi: sau da yawa - tsananin farin ciki,
- rashin lafiyan halayen: da wuya - itching, fatar fata, urticaria, amaifon firikwensin,
- daga jiki gabaɗaya: da wuya - raguwa a cikin gulukoshin jini, bayyanar alamun bayyanar cututtuka a cikin ciwon kai, ruɗami, haɓaka gumi, da kuma raunin gani.
Yawan damuwa
Bayyanar cututtuka: a bango na kashi ɗaya na 10 - 10 g na thioctic acid, shan maye mai tsanani na iya haɓakawa tare da alamomi kamar su tashin hankali mai narkewa, hauhawar hypoglycemic, damuwa mai rikicewar ma'aunin acid-base, lactic acidosis, rikicewar zubar jini mai tsanani (gami da mutuwa).
Jiyya: idan ana tsammanin yawan yawan maganin Thioctacid BV (ƙwayar cuta guda ɗaya don manya fiye da Allunan 10, yaro fiye da 50 MG a 1 kg na nauyin jikinsa), mai haƙuri yana buƙatar asibiti nan da nan tare da alƙawarin maganin rashin lafiya. Idan ya cancanta, ana amfani da maganin cututtukan anticonvulsant, matakan gaggawa na riƙe da ayyuka na mahimman gabobin.
Umarni na musamman
Tun da ethanol shine haɗari ga haɓakar polyneuropathy kuma yana haifar da raguwa a cikin tasirin warkewa na Thioctacid BV, yawan amfani da barasa yana ƙin yarda da marasa lafiya.
A cikin lura da ciwon sukari mai cutar ciwon sukari, mara lafiya yakamata ya kirkiro yanayi wanda zai tabbatar da kiyaye ingantaccen glucose a cikin jini.
Fasali na Thioctacid
A cikin kantin magani zaka iya siyan wannan kayan ta hanyar Allunan BV (sakin gaggawa) ko bayani. Don tabbatar da ingantaccen ɗaukar nauyi kuma don kawar da asarar abu, kayan da aka saki da sauri sun fi dacewa da kaddarorin thioctic acid. Acid an saki shi kuma nan da nan ya mamaye shi cikin ciki, sannan kuma da zaran ya fara nunawa da sauri. Acid na Thioctic acid baya tarawa kuma an cire shi gaba daya daga cikin jiki, saboda ana amfani dashi sosai akan farfadowa da kariya daga sel.
Ana samun Thioctacid a cikin nau'ikan allunan kawai don saurin saki, tun da tsari na yau da kullun ana nuna shi ta hanyar ƙarancin ƙwaƙwalwar ƙwaƙwalwa da ƙarancin sakamako na sakamako.
Ana shan miyagun ƙwayoyi 1 kwamfutar hannu 1 sau ɗaya kowace rana a kan komai a ciki na minti 20-30 kafin abinci - a kowane lokaci na rana. Ana iya gudanar da maganin ba tare da dilution ba, amma ana yawanci ana shafa shi a cikin gishirin kuma ana gudanar dashi a hankali, ba saurin minti 12, don haka ana yin wannan aikin a asibiti.
Babban aikin maganin shine maganin alpha-lipoic (thioctic) acid a cikin adadin 600 MG a kowace kwamfutar hannu da kowane ampoule na maganin.
A matsayin kayan taimako, mafita tana dauke da trometamol da ruwa mai bakararre don allura kuma baya dauke da sinadarin lu'ulu'u, glycol propylene da macrogol.
Allunan suna haɓaka ƙaramin abun ciki na masu sihiri, kar a ƙunshi lactose, sitaci, cellulose, oil castor, gama gari mai rahusa na thioctic acid.
Hanyoyin aikace-aikace
Aikin abu mai aiki na thiocic acid yana cikin kashi na metabolism da aka gudanar a cikin mitochondria - tsarin jikin sel da ke haifar da samar da makamashi na duniya adenosine triphosphoric acid (ATP) daga ƙoshin mai da carbohydrates. ATP ya zama dole ga duk sel su sami makamashi. Idan abu mai ƙarfin bai isa ba, to tantanin ba zai iya yin aiki yadda yakamata ba. Sakamakon haka, abubuwa daban-daban na aiki a cikin gabobin, tsokoki da tsarin jikin gaba ɗaya ke haɓaka.
Thiocic acid wani abu ne mai kyawu wanda yake kare kuzarin, yana da kusanci da Vitamin B dangane da yadda yake aiki.
A cikin ciwon sukari mellitus, dogara da barasa da sauran cututtukan cuta, ƙananan tasoshin jini sau da yawa suna rufewa kuma suna yin talauci.
Fibres na jijiya, wanda suna cikin kauri daga kyallen takarda, suna jin rashi na abinci mai mahimmanci da kuma ATP, wanda ke haifar da cututtuka. An bayyana su ta hanyar cin zarafin hankalin al'ada da kuma motsawar motar.
A lokaci guda, mai haƙuri yana jin rashin jin daɗi a yankin da jijiyar da abin ya shafa ta wuce. Abubuwan jin dadi marasa dadi sun hada da:
- Damuwa na farji na gefe (numbness, itching, kona ji a cikin ƙarshen, abin rarrafe rarrabewa)
- rikice-rikice na tsarin juyayi na kansa (gastrointestinal dyskinesia, rikice-rikice na tsarin zuciya, jijiya ƙonewa, rashin lafiyar urinary, sweating, bushe fata da sauransu)
Don kawar da waɗannan bayyanar cututtuka, mayar da abincin salula, ana buƙatar maganin Thioctacid BV. Wannan samfurin yana cika cikakkiyar bukatun ƙwayoyin saboda gaskiyar cewa an samar da isasshen ATP a cikin mitochondria.
Acid na acid a jikinta ana yinsa ne da kullun a cikin kowane ƙwayoyin jiki daidai saboda ana buƙata. Tare da raguwa a lambarta, lambobi daban-daban suna bayyana.
Magungunan yana kawar da raunin abinci mai gina jiki da alamu marasa kyau na cututtukan cututtukan zuciya. Bugu da kari, ana amfani da maganin ta hanyar ayyuka:
- antioxidant. A matsayin maganin antioxidant, yana taimakawa kare sel na tsarin da gabobin daga lalacewa ta hanyar tsattsauran ra'ayi, wanda aka kirkira yayin lalata duk abubuwan baƙin waje waɗanda ke shiga cikin jiki. Zai iya zama iskar ƙura, gishiri mai nauyi da ƙwayoyin cuta,
- maganin guba. Magungunan na taimakawa wajen kawar da bayyanar maye saboda hanzarta kawar da kawar da wasu abubuwa da ke lalata jikin mutum,
- insulin-kamar. Ya ta'allaka ne a cikin ikon da miyagun ƙwayoyi don rage taro na sukari a cikin jini ta hanyar ƙara yawan amfani da shi ta sel. Saboda haka, miyagun ƙwayoyi suna daidaita ƙwayar cutar glycemia a cikin marasa lafiya da ciwon sukari, inganta lafiyar gaba ɗaya kuma suna aiki a matsayin insulin nasu,
- ba da gudummawa ga asarar nauyi (daidaita al'ada mai yawa, yana karya kitse, yana haɓaka ayyukan gaba ɗaya da inganta walwala),
- hepatoprotective
- kyakyawan aiki,
- ragewan lipid.
Yana da muhimmanci a tuna cewa ya zama dole a bi duk rubutattun likitan likitanci don lura da cututtukan da ke tattare da cutar - ciwon sukari.
Alamu don amfani da Thioctacid (BV)
Kamar yadda aka riga aka ambata, an nuna magungunan don kawar da neuropathy da polyneuropathy a cikin dogara da giya da mellitus na sukari (wanda aka tabbatar da sake dubawa daga likitoci da masu haƙuri).
Ya kamata a dauki allunan Thioctacid guda ɗaya a ciki sau 30 kafin abinci. An cinye maganin duka (ba tare da taunawa ba) kuma an wanke shi da ruwa.
Tsawan likitan ne zai tantance tsawon lokacin da likitan yake ciki a kowane yanayi. Intensarfin jiyya zai dogara da:
- tsananin tsananin cutar,
- rashi wanda alamomin sa suka shuɗe
- janar yanayin haƙuri.
An bada shawarar dogon jiyya, tunda kayan abu ne na jiki kuma baya tarawa. A zahiri, wannan shine maganin maye. Sabili da haka, mafi ƙarancin darajan shine watanni 3 (akwai fakiti kan allunan 100, mafi tattalin arziƙin saya). Akwai nazarin ci gaba na gudanarwa na tsawon shekaru 4, wanda ya nuna kyakkyawan haƙuri da amincin ƙwayoyi. Yawancin marasa lafiya suna ɗaukar shi akai-akai, tunda ana lalata tasirin cutar a kan ƙwayar jijiya kuma jiki yana buƙatar wannan kayan koyaushe.
Tare da yanayin musamman na cutar da bayyanar alamun bayyanar cututtukan neuropathy, ana nuna cewa masu ciwon sukari suna ɗaukar maganin Thioctacid a cikin makonni 2-4. Bayan wannan canzawa ne kawai don amfani da Thioctacid na 600 a kowace rana.
Amfani da Thioctacid T
Ana amfani da maganin maganin Tioctacid T (600 mg) a cikin aikin likita don gudanar da aikin kai tsaye. Abun yana da hoto, saboda haka ampoules sunyi duhu a launi, kuma kwalban da maganin yana rufe gashi. Cikin nutsuwa cikin nutsuwa. Kashi 600 MG (1 ampoule) kowace rana. Dangane da takardar da likita ya bayar, yana yiwuwa a kara kashi dangane da yanayin mai haƙuri.
Idan neuropathy a cikin ciwon sukari mai tsanani ne, to ana gudanar da maganin ne a cikin jiji na 2 zuwa 4 makonni.
A yanayin yayin da mai haƙuri ba zai iya karɓar droplet na Thioctacid 600 T a cikin asibiti ba, idan ya cancanta, ana iya maye gurbinsu ta hanyar amfani da allunan Thioctacid BV a cikin daidaitaccen sashi, tunda suna ba da isasshen matakin warkewa na kayan aiki a cikin jiki.
Dangane da ka'idojin kulawa na Ma'aikatar Lafiya na Tarayyar Rasha, an nuna thioctic acid don hepatitis, radiculopathies, da dai sauransu.
Dokoki don gabatarwa da ajiyan magani
Idan likita ya tsara jiko na ciki, to mara lafiya ya san cewa ya kamata a gudanar da duk girman yau da kullun a lokaci guda. Idan ya cancanta, shigar da 600 MG na abu ya kamata a dilce cikin ruwan gishiri (zaka iya har ma da ƙaramin adadin). Kwakwalwa koyaushe ana yin sa a hankali a matakin da bai wuce 1.7 ml a cikin 60 seconds ba - ya danganta da ƙimar Saline (ana gudanar da ruwa na 250 a cikin minti 30-40 don guje wa hemostasis). Masu bita sun ce irin wannan tsari ga masu ciwon sukari ba shi da kyau.
Idan ana buƙatar sarrafa magungunan kai tsaye cikin ƙwayar cuta, to a wannan yanayin ana ɗaukar hankalin kai tsaye daga ampoule cikin sirinji kuma an haɗa famfon sirinji a ciki, wanda ke ba da izinin mafi ingancin allurar. Gabatarwa cikin jijiya ya kamata ya zama mai jinkiri kuma ba ya wuce minti 12.
Saboda gaskiyar cewa maganin da aka shirya na Thioctacid yana da matukar damuwa ga haske, an shirya shi nan da nan kafin amfani. Ampoules tare da kayan kuma ana cire shi kawai kafin amfani. Don hana mummunan tasirin haske, akwati tare da maganin da ya ƙare yakamata a rufe shi da tsare.
Ana iya adanar shi ta wannan tsari tsawon fiye da awanni 6 daga ranar da aka shirya.
Cases yawan abin sama da ya faru da kuma m halayen
Idan yawan abin sama da ya faru ya faru saboda dalilai daban daban, to alamomin sa zasu kasance:
- yawan tashin zuciya
- gagging
- ciwon kai.
Lokacin ɗaukar yawan maye, Thioxide BV yana bayyana ta hanyar bacin rai da damuwa da damuwa. Sannan lactic acidosis da bugun zuciya na riga sun ci gaba.
Babu takamaiman maganin rigakafi ba ya wanzu. Idan kana da damuwa game da maye, to yana da mahimmanci a tuntuɓi cibiyar likita da wuri-wuri don matakai na warkewar cututtukan da za su iya kawar da jiki.
Hulɗa da ƙwayoyi
Tare da amfani da Thioctacid BV lokaci guda:
- cisplatin - lowers da warkewa sakamako,
- insulin, maganganun hypoglycemic na mahaifa - na iya haɓaka tasirin su, saboda haka, ana buƙatar saka idanu na yau da kullun game da matakan glucose na jini, musamman a farkon haɗuwa da magani, idan ya cancanta, an yarda da rage yawan ƙwayoyin cutar hypoglycemic,
- ethanol da metabolites - haifar da rauni na miyagun ƙwayoyi.
Wajibi ne yin la'akari da dukiyar thioctic acid zuwa ga ɗaurin ƙananan ƙarfe yayin haɗuwa da kwayoyi waɗanda ke ɗauke da baƙin ƙarfe, magnesium da sauran ƙarfe. An ba da shawarar a shigar da kudin shigarsu zuwa yamma.
Reviews on Thioctacide BV
Binciken Thioctacide BV shine mafi yawan lokuta tabbatacce. Marasa lafiya tare da masu ciwon sukari suna nuna raguwa a cikin sukari jini da matakan cholesterol, ingantacciyar kiwon lafiya ta fuskar tushen tsawaita amfani da miyagun ƙwayoyi. Wani fasalin magungunan shine saurin sakin maganin thioctic acid, wanda ke taimakawa hanzarta tafiyar matakai na rayuwa tare da cire mayukan kitse mai narkewa daga jiki, canzawar carbohydrates zuwa makamashi.
Ana lura da ingantaccen sakamako na warkewa yayin amfani da magani don maganin hanta, cututtukan cututtukan zuciya, da kiba. Kwatanta tare da analogues, marasa lafiya suna nuna ƙananan abin da ya faru na tasirin da ba'a so ba.
A cikin wasu marasa lafiya, shan maganin ba shi da tasirin da ake tsammanin a cikin rage ƙwayar kolesterol ko ba da gudummawa ga ci gaban urticaria.