Glibomet: sake dubawa game da masu ciwon sukari, umarnin don amfani, abun da ke ciki, contraindications

Shan magungunan hana daukar ciki na zama dole wasu lokuta, musamman idan aka sami masu cutar sukari wadanda suke bukatar wasu magunguna don daidaita sukarin jini. Tabbas, a cikin kasuwar magunguna ta zamani akwai irin waɗannan magunguna. Amma galibi masana suna bada shawarar maganin "Glibomet." Nazarin masu ciwon sukari da likitoci sun nuna cewa da gaske wannan magani yana ba ku damar jimre da yanayin rikicin.

Bayanin abun da ke ciki. Tsarin Sakin Magunguna

Magungunan "Glibomet" yana samuwa a cikin nau'i na farin allunan zagaye tare da harsashi mai wuya. An sanya su cikin fitsarar roba na guda 20. A cikin kantin magani zaka iya siyan sikelin wanda ya ƙunshi blisters biyu.

Wannan haɗin kayan aiki ne, sabili da haka, abun da ke ciki ya ƙunshi abubuwa biyu masu aiki - glibenclamide (2.5 ml a cikin kwamfutar hannu ɗaya) da metformin a cikin nau'in hydrochloride. Tabbas, shirye-shiryen sun ƙunshi abubuwa masu taimako, musamman, sitaci masara, silicon dioxide, microcrystalline cellulose, talc, diethyl phthalate, glycerin, cellulose acetate phthalate, gelatin.

Yaya miyagun ƙwayoyi ke shafar jikin?

Tabbas, don farawa, yana da mahimmanci fahimtar kaddarorin magungunan. Tasirin hypoglycemic na shirye-shiryen Glibomet an ƙaddara shi ta hanyar abubuwan da ke cikin abubuwa biyu masu aiki gaba ɗaya.

Wannan kayan aiki yana aiki akan maganin farji, shine akan waɗancan rukunin yanar gizon da ke da alhakin haɗarin insulin a cikin jiki. A lokaci guda, maganin yana inganta haɓakar ƙwaƙwalwar ƙwayoyin cuta zuwa wannan hormone. Saboda haka, Glibomet yana taimakawa rage jini na jini ba tare da yin amfani da insulin roba ba, wanda yake da matukar muhimmanci ga masu ciwon sukari na 2.

Har ila yau, maganin yana da kaddarorin rage kiba. A ƙarƙashin tasirinsa, matakin mai a cikin jini yana raguwa, wanda ke rage yuwuwar clots a cikin jini (ƙwanƙwasa jini). Metformin yana cikin rukunin biguanides. Wannan abu yana kunna ayyukan amfani da glucose ta tsokoki, yana hana gluconeogenesis a cikin hanta hanta, kuma yana hana adsorption na carbohydrates ta bangon hanji.

Glibenclamide yana ɗaukar hanzari ta ganuwar hanjinsa kuma ya kusan kasancewa gaba ɗaya (97%) yana ɗaukar garkuwar plasma. A cikin hanta, sai ya rushe, yana haifar da metabolites marasa aiki, wanda daga nan sai aka fitar daga jiki tare da jijiyoyi da fitsari. Rabin rayuwar shine 5 hours. Hakanan ana amfani da Metformin cikin hanzari a cikin jiki, amma baya daure wa garkuwar plasma. Wannan abun ba a jikin metabolized a jiki. Rabin rayuwar shine awa biyu.

Yaushe ake amfani da maganin?

Mutane da yawa suna fama da wata cuta kamar ciwon sukari na 2. Abinci da magani a wannan yanayin suna da matukar muhimmanci. A matsayinka na mai mulki, ga marasa lafiya suna cin abincin da ya dace. Zaka iya daidaita sukarin jininka tare da sulfonylureas.

Magungunan "Glibomet" an wajabta shi idan maganin abinci da shan kudaden da ke sama ba su bayar da tasiri ba.

Sashi da shawarwari don amfani

Yaya za a sha maganin "Glibomet"? Sashi ne m akayi daban-daban. A matsayinka na mai mulkin, kashi na farko shine allunan biyu. An kwashe su da abinci. Bugu da ari, adadin ƙwayar yana ƙaruwa don cimma sakamako mafi girma. Yawan yau da kullun kada ya wuce 2 g na metformin. Na gaba, ana rage rage kashi a hankali.

Magungunan "Glibomet": contraindications don magani

Wannan ingantaccen iko ne, magani mai mahimmanci, liyafar wacce zata yiwu kawai tare da izinin likita. A miyagun ƙwayoyi yana da wani kyakkyawan ban sha'awa jerin contraindications, wanda ya kamata ka sani da kanka tare da fara fara magani:

hypersensitivity ga aiki da kuma kayan taimako na Allunan,
rashin lafiyan sauran abubuwan da ake amfani da su na sulfonylurea, kazalika da sulfamide, probenecid ko di sulfates,
wannan magani yana contraindicated a cikin mata yayin daukar ciki,
rashin sakamako daga far,
ciwon sukari na ciki da yanayin predomatous
mummunan rauni na koda, gazawar koda,
bushewa
cututtuka
cututtuka na kumburi wanda zai iya haifar da ci gaban hypoxia,
ciwo mai zurfi na tsarin zuciya da jijiyoyin jini, gami da matsaloli tare da kewaya gefe, rashin isasshen ƙwayar cuta, ƙonewa mai guba da rawar jiki,
cututtukan baya da suka gabata na tsarin numfashi,
karancin infarction na asali ko lokacin gyarawa bayan shi,
Lokaci guda na amfani da diuretics da magunguna don cutar hawan jini,
acidosis ko hadarin ci gabansa,
kasancewar a cikin tarihin mai haƙuri game da lokuta na lactic acidosis,
mummunan cutar hanta
rikicewar tsarin na numfashi,
lokacin murmurewa bayan an cire wani bangare na cutar kansa,
hanyoyin maganin dystrophic,
na kullum barasa, a jihar m barasa maye,
m zub da jini
'yan ta'adda
lactation
azumi ko bin tsaftataccen abinci.

Idan kuna da kowane ɗayan abubuwan da ke sama, to, yana da mahimmanci a ba da rahoto ga endocrinologist.

Wadanne illa za su haifar?

Shin koyaushe ana ɗaukarsa mai lafiya don ɗaukar allunan Glibomet? Sakamakon sakamako na gefen magani yana yiwuwa. Magungunan abubuwan da suka faru, duk da haka, ba a yin rikodin su sau da yawa, amma magani na iya shafan tsarin kwayoyin halitta daban-daban.

Tsarin Lymphatic da jini. Hemolytic anemia, leukopenia, thrombocytopenia, pancytopenia, erythrocytopenia.
CNS. Lokaci-lokaci yana faruwa da ciwon kai, tsinkaye mara kyau.
Amfani da hango nesa. Rashin daidaituwa na masauki, rage ƙarancin gani na gani, wanda ke da alaƙa da canji a cikin sukarin jini.
Tsarin rayuwa. Sharparin haɓakawa a cikin nauyin jiki, hypoglycemia, lactic acidosis. Yin magani na dogon lokaci wani lokacin yakan haifar da rauni ga ƙwayar bitamin B12 a cikin hanji, wanda daga baya yake ba da gudummawa ga ci gaban megaloblastic anemia.
Tsarin narkewa. Ciwon hanci, amai, amai, zafi a cikin yankin, ciwan wuya, rashin cin abinci, bayyanar dandano mai ƙarfe a cikin bakin, jin daɗin ciki na ciki.
Fata da ƙananan nama. Fata mai narkewa, erythema, nau'ikan nau'ikan exanthema, haɓaka yanayin ƙirar fata zuwa haske, rashin lafiyar dermatitis, urticaria.
Allergic halayen. Rashes a kan fata, kumburi, jaundice, raguwa mai kaifi a cikin karfin jini, bacin rai, yanayin girgizawa.
A hanta. Choraphis intrahepatic, maganin cutar hepatitis.
Wasu rikice-rikice na iya bayyana, musamman, haɓaka yawan fitsari yau da kullun, asarar furotin da sodium ta jiki sakamakon lalacewar ƙura a cikin kodan.

Yana da kyau a lura cewa yawancin rikice-rikicen da ke sama ba sa buƙatar dakatar da maganin jiyya - ya isa don rage kashi kuma halayen da ba su dace ba su tafi da kansu. Dole ne a ƙara adadin ƙwayar yau da kullun a hankali kuma a hankali.

Bayanai kan ma'amala da wasu kwayoyi

Ba za a iya ɗaukar magani ba "Glibomet" (metformin) tare da barasa na ethyl, saboda wannan yana ƙaruwa da damar haɓakar lactic acidosis. A lokacin aikin tiyata, barasa da abubuwan sha da ke ɗauke da giya dole ne a jefar dasu.

An dakatar da amfani da wannan magani 48 hours kafin hanyoyin da ake amfani da waken bambancin aidin. Amfani da wadannan magunguna a lokaci daya zai iya haifar da ci gaban kiba koda.

Idan kun dauki "Glybomet" tare da insulin, steroids anabolic, beta-adrenergic blockers, magungunan tetracycline, to, haɗarin haɓakar haɓakar jini yana ƙaruwa. Masu ciwon sukari koyaushe suna buƙatar sanar da likita game da duk magungunan da suke sha.

Cost da analogues

A cikin maganin zamani, ana amfani da maganin "Glibomet" sau da yawa. Reviews na masu ciwon sukari, alamu da contraindications ne, ba shakka, mahimman maki. Amma ba ƙaramin mahimmanci ba ne farashinsa. Tabbas, yana da wuya a faɗi ainihin lambar, amma a matsakaici farashin kunshin 40 Allunan ya tashi daga 340 zuwa 380 rubles, wanda a zahiri ba shi da yawa.

Tabbas, wannan maganin ba koyaushe dace da marasa lafiya. Akwai isassun musanya a kasuwar hada magunguna ta zamani. Misali, tare da ciwon sukari na nau'in na biyu, irin su Avandamet, Vokanamet, Glukovans galibi ana amfani dasu. Ba ƙasa da sau da yawa, ana tsara marasa lafiya Dibizid, Dianorm ko Sinjarji. Tabbas, kawai halartar endocrinologist na iya zaɓar ingantaccen analog.

Magungunan "Glibomet": sake dubawa game da masu ciwon sukari da likitoci

Ana amfani da wannan magani sosai a maganin zamani. Amma menene magani da Glibomet yayi kama da gaske? Nazarin masu ciwon sukari, har ma da masana, sun tabbatar da cewa miyagun ƙwayoyi suna magance lafiya sakamakon sakamakon rashin lafiyar insulin-da ke fama da rashin lafiyar insulin.

Dangane da bincike, ƙwayar tana kunna ɓangaren ƙwayar cuta wanda ke da alhakin haɗarin insulin. Wannan shine ainihin abin da ake buƙata don cuta irin su ciwon sukari na 2. Abinci da magani a wannan yanayin suna da matukar muhimmanci.

Ba a daɗe da rikodin maganganun halayen da ba su dace ba a cikin aikin likita. An yarda da maganin sosai, kuma farashinsa na da ma'ana.

Tasirin maganin a jikin mutum

Yawancin binciken da kwararrun masana duniya suka gudanar sun tabbatar da cewa matakin maganin, wanda ke da INN da ake kira Metformin, ya fara awanni biyu bayan amfani da shi, kuma ya kare ne bayan awanni 12. Ya isa ga mai haƙuri ya ɗauki sau biyu a rana don tabbatar da rayuwa mai kyau da ƙoshin lafiya. Dole ne mai haƙuri ya fahimci yadda ya kamata a sha magunguna tare da nau'ikan nau'ikan ciwon sukari.

Wasu marasa lafiya suna koka da sakamako na sakamako daga amfani da miyagun ƙwayoyi, yana faruwa a cikin haƙuri a gaban mutum rashin haƙuri ga abubuwan da miyagun ƙwayoyi. Yana da mahimmanci a bincika dacewar jikin mutum tare da abubuwan da ke cikin miyagun ƙwayoyi sannan kuma a fara magani.

Bayan shan kwayoyin, jikin zai fara yin insulin da sauri. Bayan shan magani, yawancin lokuta suna haɗu da su fiye da farkon jiyya. Babban abu mai aiki yana da tasirin cututtukan fata a jikin jikin mutum, amma biguanide da ke cikin magungunan yana da tasirin karin-pancreatic - aiki mai kyau na gulukos wanda jikin mai haƙuri zai fara.

Wasu marasa lafiya sun yi imanin cewa don murmurewa mai inganci ya isa ya sha wasu magunguna kuma kiwon lafiya zai inganta. Bai isa ba kaje ga likita ka gaya masa wani abu kamar haka ko zaka iya taimakawa wajen kawar da ciwon sukari ko kuma ka gaya mani, don Allah, kwaya mafi inganci da amfani, misali, barasa. Lokacin da za a kawar da ciwo, yana da mahimmanci a bi abincin da ya dace kuma a ɗora jiki tare da isasshen aikin jiki. Kar a cika kayan jiki kada ya kasance.

Idan mai haƙuri ya haɗu da amfani da magunguna, daidaitaccen abinci da aikin jiki, to zai iya samun sakamako mai kyau.

Abubuwan kwantar da hankali ga yin amfani da magani

Yana da mahimmanci a amince da likitan ku ba da ra'ayin wasu marasa lafiya ba.

Haɗin glibenclamide da metformin zasu taimaka wajen riƙe matakin sukari na jiki a cikin kewayon yarda ga ɗan adam.

Kamar kowane magani, glibomet wanda ke dauke da glibenclamide da metformin suna da wasu magunguna.

Babban maganin hana amfani da miyagun ƙwayoyi sune kamar haka:

nau'in ciwon sukari guda 1
lactic acidosis lokacin,
coma mai ciwon sukari ko concomitant
cututtukan da ke tattare da keta cinikin abinci,
hadaddun kamuwa da cuta wanda zai iya haifar da ci gaban koda,
matsaloli na hanta da yawa.

Jikin mai ciwon suga yana fama da wasu cututtuka da yawa da rikice-rikice a cikin aikin gabobin ciki, haɓaka gaba da tushen cutar. Saboda haka, kafin fara lura da babban cutar tare da kowane magani, yana da mahimmanci a bincika jikin sosai don sanin yiwuwar mai haƙuri yana da sakamako masu illa da mummunan sakamako daga shan miyagun ƙwayoyi.

Yana da mahimmanci a fahimci ainihin menene maganin ya dace da wani mai haƙuri, shin zai yiwu a zaɓi analog na maganin. Amma game da analog, ya kamata a kula don zaɓar wanda ya fi dacewa. Yawancin likitoci suna ba da shawarar marasa lafiya su canza maganin idan wani sakamako na gefen ya fara bayyana. Glucophage ya shahara kamar analog, wanda ke da tasiri iri ɗaya akan jikin mai haƙuri.

Don zaɓar mafi kyawun ƙwayar cuta, ana bada shawara, lokacin zabar magani, yin nazari dalla-dalla game da umarnin don amfani da magani kuma mai haƙuri ya yi bita game da shi. Yin nazarin umarnin don amfani da miyagun ƙwayoyi Glibomet da sake dubawa na marasa lafiya game da shi yana ba mu damar fahimtar duk abubuwan da ake amfani da su na samfurin ƙayyadadden aikin likita kuma yin amfani da shi ba shi da lahani kuma yana da tasiri.

Kafin sayen magani, Glybomet ya zama dole don sanin kanka tare da umarnin don amfani, ana samun irin wannan bayanin a yanar gizo, idan ana so, kowa na iya samun masaniya a kowane lokaci.

Bayyanar da sakamako masu illa

Kayan aiki yana da ƙuntatawa na shekaru. Ba a ba da shawarar marasa lafiya da ke ƙasa da shekara goma sha takwas don amfani da su ba.

Ana iya siyan magungunan a kowane kantin magani a Rasha. Kuna buƙatar yin haka bayan tuntuɓar likitanka da karɓar takardar sayan magani daga gare shi. Hakanan ya shafi yanayin inda mai haƙuri ya yanke shawarar maye gurbin miyagun ƙwayoyi tare da analog.

Za'a iya aiwatar da sauyawa daga magani bayan likita ta halarta kuma ya bayar da shawarar sa. Tsanani yana da alaƙa da gaskiyar cewa babban sinadari mai aiki shine metformin, wanda ya zama, idan aka sami yawan abin sama da yawa, sanadiyyar haɓakar ƙwayar cutar sukari a cikin haƙuri. Glybomet bai cancanci farawa da maganin ba.

Dangane da duk bayanan da aka bayyana a sama, shan miyagun ƙwayoyi Glibomet a cikin allunan na iya hade da sakamako masu illa kamar:

Qarfin kai nabol.
Ciwon sukari
Matsalar jini (ƙwanƙwasa jini, da sauransu).
Ragewa daga tsarin juyayi na tsakiya.
Rashin lafiyar rashin lafiyar fatar jiki da ƙari.

Sabili da haka, a farkon gano irin waɗannan bayyanar cututtuka bayan shan Glibomet, ya kamata ku nemi shawarar likita nan da nan kuma, idan ya cancanta, nan da nan neman wanda zai maye gurbin wannan magani, in ba haka ba kuna iya cutar da lafiyarku har ma da ƙari.

Umarnin don amfani da miyagun ƙwayoyi

Babu ƙarancin muni shine tambayar yadda ake ɗaukar kayan aikin da ke sama. Likitanku zai iya bayar da bayanai kan yadda ake daukar Glibomet daidai. Shi kadai, bayan cikakken bincike na mai haƙuri, zai iya bayar da shawarar jigilar magani wanda ya faɗi abin da sashi na maganin ya kamata da kuma jadawalin gudanarwa.

A farkon farawa, an tsara mafi ƙarancin adadin, yana ɗauka daga alluna ɗaya zuwa uku. To, idan ya cancanta, wannan sashi na iya ƙaruwa. Matsakaicin adadin allunan da mai haƙuri ɗaya na iya ɗauka yayin rana bai wuce guda shida ba.

An bayyana wannan dalla-dalla ta hanyar bayani game da maganin, wanda aka haɗe da kowane kunshin magani. Amma ya ƙunshi kawai ba daidai adadin ba, amma har da ainihin abun da ke ciki na samfurin. Sabili da haka, idan mai haƙuri yana da rashin lafiyan kowane ɓangaren, yana iya sanar da likita kafin wannan, tun da farko ya karanta umarnin.

Dangane da farashin magungunan, yana iya bambanta dan kadan dangane da adadin abubuwan da ke cikin aikin da ke kunshe a cikin maganin. A matsakaici, farashi ya kasance daga ɗari biyu zuwa ɗari uku rubles.

Glibomet 2.5 yana da ɗan rahusa fiye da ɗaya samfurin, wanda ya haɗa da 5 MG na babban abu, shine Glibomet 5 +400.

Menene mahimmanci a tuna lokacin amfani da Glibomet?

Kafin ka fara amfani da Glibomet na miyagun ƙwayoyi, yakamata a yi nazarin umarnin dalla-dalla, kana buƙatar karanta hoton kunshin magungunan don fahimtar daidai ko an sayo maganin.

Kamar yadda aka ambata a sama, akwai tsoffin maganganu da likitoci za su iya ba da shawarar. Daga cikin su, babban magani shine Glucofage 850. Yawancin marasa lafiya suna ƙoƙarin gano wanda yafi kyau a tsakanin waɗannan magunguna guda biyu. Zai yi wuya a bayar da tabbataccen amsar. Dukkan abubuwan sun dogara da yanayin mutum na jikin mai haƙuri da tsananin cutar.

Kasancewar cututtukan concomitant kuma suna taka muhimmiyar rawa. Idan akwai matsaloli tare da hanta, to kuna buƙatar yin hankali lokacin da aka tsara magani. Zai fi kyau a wannan yanayin koyaushe ɗaukar kwayoyi a layi daya waɗanda ke tallafa wa aikin hanta kanta, alal misali, Essentiale forte. Haka kuma, ma'amala da wannan magani tare da hypoglycemic hakika tabbatacce ne. Hakanan za'a iya ba da shawara guda ɗaya game da tsarin kulawa, wanda ya ba da shawara cewa kuna buƙatar ɗaukar glucophage.

An riga an faɗi a sama cewa tsawon lokaci ba a ba da shawarar Glibomet don amfani da marasa lafiya waɗanda ke ƙasa da shekara 18 ba. Sabili da haka, idan akwai buƙatar zaɓar magani don yaro, wannan gaskiyar dole ne a la'akari.

Akwai magunguna da yawa waɗanda Maninil ke ciki. Sabili da haka, koyaushe zaka iya zaɓar mafi kyawun aikin jiyya don wani haƙuri.

Wasu marasa lafiya suna tunanin cewa Glucophage da Glybomet kalmomin juna ne. Amma wannan kuskure ne, waɗannan magunguna biyu ne daban-daban, kodayake akwai kamanni da yawa a tsakanin su. Haka kuma, duka a hade kuma cikin sharuddan tasirin jiki.

Dole ne koyaushe a hankali zaɓi sashi na miyagun ƙwayoyi dangane da shawarar tsarin kulawa da magani. Bayan haka, akwai Allunan da ke dauke da 2.5 MG na kayan aiki, kuma akwai wadanda suka hada 5 MG na bangaren guda.

Wadanne magungunan cututtukan cututtukan cututtukan ƙwayar cuta ne suka fi tasiri a cikin bidiyon wannan labarin.

Mai yiwuwa Glibomet ya maye gurbin

Bagomet Plus (Allunan) Rating: 37

Analog ɗin yana da rahusa daga 78 rubles.

Mai samarwa: Kimika Montpellier (Argentina)
Siffofin Saki:

Tab. 2.5 MG + 500 MG, 30 inji mai kwakwalwa.
Tab. 5 MG + 500 MG, 30 inji mai kwakwalwa.

Umarnin don amfani

Morearin amfani da Glibomet na Argentinean da ke da riba mai yawa tare da wannan saiti na kayan aiki masu aiki, amma a cikin ɗan ƙaramin sashi daban. Ba kamar package ɗin "na asali" ya ƙunshi allunan 10 ƙasa da ƙasa ba, don haka tare da tsawan magani, fa'idodin kuma zai zama ƙasa.

Metglib (Allunan) Rating: 47

Analog mai rahusa daga 72 rubles.

Wannan bayanin analog a cikin zaɓi na abubuwa masu aiki da kuma sashi ɗaya akan kwamfutar hannu 1 ba su da bambanci da Glibomet. Ana sayar da shi a cikin nau'in saki kuma an yi niyya don maganin cututtukan type 2. Akwai contraindications da sakamako masu illa.

Analog ne mai rahusa daga 46 rubles.

Glucovans akan farashin marufi yana gwada dacewa tare da "asalin" magani, amma ya ƙunshi Allunan 10 ƙasa. Alamu masu amfani iri daya ne. Ana amfani da Glucovans don nau'in ciwon sukari na 2 na sukari da rashin daidaituwa na abinci da aiki na jiki.

Analogs Glibomet

Yayi daidai da alamun

Farashi daga 90 rubles. Analog mai rahusa ne ta hanyar 197 rubles

Yayi daidai da alamun

Farashi daga 97 rubles. Analog mai rahusa ta hanyar 190 rubles

Yayi daidai da alamun

Farashin daga 115 rubles. Analog ɗin yana da rahusa ta 172 rubles

Yayi daidai da alamun

Farashin daga 130 rubles. Analog ne mai rahusa ta 157 rubles

Yayi daidai da alamun

Farashin daga 273 rubles. Analog ne mai rahusa ta hanyar 14 rubles

Yayi daidai da alamun

Farashi daga 288 rubles. Analog ya fi tsada ta 1 rubles

Yayi daidai da alamun

Farashin daga 435 rubles. Analog ya fi tsada ta 148 rubles

Yayi daidai da alamun

Farashin daga 499 rubles. Analog ya fi tsada ta 212 rubles

Yayi daidai da alamun

Farashin daga 735 rubles. Analog ya fi tsada a 448 rubles

Yayi daidai da alamun

Farashi daga 982 rubles. Analog ɗin ya fi tsada a kan 695 rubles

Yayi daidai da alamun

Farashi daga 1060 rubles. Analog ya fi tsada ta hanyar 773 rubles

Yayi daidai da alamun

Farashin daga 1301 rubles. Analog ya fi tsada ta 1014 rubles

Yayi daidai da alamun

Farashin ya kasance daga 1395 rubles. Analog ya fi tsada a 1108 rubles

Yayi daidai da alamun

Farashin ya kasance daga 1806 rubles. Analog ya fi tsada ta 1519 rubles

Yayi daidai da alamun

Farashin ya kasance daga 2128 rubles. Analog ɗin ya fi tsada a 1841 rubles

Yayi daidai da alamun

Farashi daga 2569 rubles. Analog ya fi tsada a 2282 rubles

Yayi daidai da alamun

Farashin daga 3396 rubles. Analog ya fi tsada 3109 rubles

Yayi daidai da alamun

Farashi daga 4919 rubles. Analog ɗin ya fi tsada a 4632 rubles

Yayi daidai da alamun

Farashi daga 8880 rubles. Analog ya fi tsada akan 8593 rubles

Tsarin saki, abun da aka shirya da marufi

Allunan mai rufi fararen, zagaye, biconvex, tare da hadarin-gefe, kamshi.

Shafin 1
glibenclamide	2.5 MG
metformin hydrochloride	400 MG

Fitattun abubuwa: microcrystalline cellulose - 65 mg, sitaci masara - 57.5 mg, colloidal silicon dioxide - 20 mg, gelatin - 40 mg, glycerol - 17.5 mg, talc - 15 mg, magnesium stearate - 7.5 mg.

Harsashi abun da ke ciki: acetylphthalyl cellulose - 2 MG, diethyl phthalate - 0.5 MG, talc - 2.5 MG.

Guda 20. - blister (2) - fakitoci na kwali.
Guda 20. - blister (3) - fakitoci na kwali.
Guda 20. - blister (5) - fakitoci na kwali.

Aikin magunguna

Haɗaɗɗen maganin magana na baki yana ƙunshe da tsarin tushen jini na ƙarni na biyu da biguanide. Yana da cututtukan cututtukan cututtukan fata da cututtukan cututtukan fata.

Glibenclamide - Abubuwan da aka samo asali na sulfonylurea na ƙarni na biyu. Yana karfafa insulin ɓoyewa ta hanyar rage ƙwanƙwasawa don haɓakar glucose β-cell na haushi, yana ƙara ƙwarewar insulin da ɗaurin ɗaurinsa ga ƙwaƙwalwar ƙwaƙwalwa, yana haɓaka sakin insulin, haɓaka aikin insulin akan ƙwayar tsoka da haɓakar hanta, kuma yana hana lipolysis a cikin tsopose nama. Ayyuka a cikin mataki na II na insulin insulin.

Metformin mambobi ne na rukunin biguanides. Yana ƙarfafa yanayin jijiyar kyallen takarda zuwa aikin insulin (yana ƙara ɗaukar nauyin insulin a cikin masu karɓa, yana inganta tasirin insulin a matakin postreceptor), yana rage glucose na hanji, yana hana gluconeogenesis kuma yana da tasiri mai amfani akan metabolism, yana taimakawa rage ƙimar ƙarfin jiki a cikin marasa lafiya tare da masu ciwon sukari mellitus, da Har ila yau yana da tasirin fibrinolytic ta hanyar dakatar da nau'in mai hana nau'in plasminogen mai kunnawa mai hanawa.

Tasirin hypoglycemic na maganin yana tasowa bayan sa'o'i 2 kuma yana ɗaukar awanni 12.

Haɗin synergistic na kayan aiki guda biyu na miyagun ƙwayoyi - tasirin mai tasiri na ƙwayar sulfonylurea dangane da samar da insulin na endogenous insulin (sakamako na pancreatic) da kuma kai tsaye tasirin biguanide akan ƙwayar tsoka da ƙoshin mai (haɓaka mai girma a cikin ƙwayar glucose - karin-pancreatic sakamako) da ƙwayar hanta (raguwa a cikin gluconeogenesis), yana ba da damar wani allurai rage abubuwan kowane bangare. Wannan yana taimakawa wajen nisantar da kuzarin β-sel na farji, sabili da haka, rage haɗarin aikin mai rauni, haka kuma yana inganta amincin magunguna tare da rage yawan tasirin sakamako.

Pharmacokinetics

Tsotsa da rarrabawa

Cikin sauri da adalci gaba ɗaya (84%) yana narkewa daga narkewar abinci, lokacin zuwa C_max shine 1-2 a rana. Yin jingina ga ƙwayoyin plasma - 97%.

Metabolism da excretion

An kusan kusan metabolized a cikin hanta don metabolites na aiki. Kodan ya cire shi (50%) kuma da bile (50%). T_1/2 yana daga awa 5 zuwa 10

Tsotsa da rarrabawa

An cika shi sosai a cikin narkewa, ana rarraba shi da sauri a cikin nama, a zahiri ba a ɗaura shi da sunadaran plasma.

Metabolism da excretion

Ba'a taɓa yin amfani dashi a cikin jikin mutum, an cire shi gaba ɗaya ta hanyar kodan kuma, a wani ɓangaren, ta hanjin ciki. T_1/2kamar 7 hours

- nau'in ciwon sukari na 2 na rashin ƙarfi tare da rashin ingancin maganin abinci da kuma maganin da ya gabata tare da sulfonylureas ko biguanides, da sauran wakilai na maganganu na baki.

Sakawa lokacin

Ana ɗaukar maganin a baka tare da abinci.

Dokar da za a iya amfani da ita da kuma tsawon lokacin jiyya ita ce ta likitan da ke halartar ya danganta da yanayin metabolism din da kuma yawan glucose a cikin jini.

Matsayi na farko yawanci shine allunan 1-3 / rana tare da ƙarin zaɓi na yau da kullun na ingantaccen kashi har sai an sami daidaituwa akan daidaituwa na glucose a cikin jini.

Matsakaicin maganin yau da kullun na miyagun ƙwayoyi Glibomet ® shine allunan 6.

Umarni na musamman

A yayin jiyya, dole ne marassa lafiya su bi shawarar likita game da sashi da hanyar amfani da miyagun ƙwayoyi, kazalika da bin tsarin abinci, tsarin motsa jiki da kuma sa ido kan matakan glucose na jini.

Lactic acidosis cuta ce mai wuya kuma mai haɗarin rayuwa wanda ke tattare da haɗarin lactic acid a cikin jini, wanda mai yiwuwa ya haifar da tarin metformin. Abubuwan da aka bayyana game da haɓakar lactic acidosis a cikin marasa lafiya da ke karɓar metformin an lura da su musamman a cikin marasa lafiya da ke fama da ciwon sukari tare da mummunan bugun zuciya da gazawar koda. Yin rigakafin lactic acidosis ya ƙunshi gano duk abubuwan haɗari masu haɗari, irin su ƙonewar ƙwayar cuta ta hanji, ketosis, yin azumi mai yawan gaske, yawan shan barasa, gazawar hanta da duk wani yanayin da ke tattare da hypoxia.

Lokacin ɗaukar Glibomet ®, ya kamata a sa ido akan abubuwan tattara ƙwayoyin ƙwayoyin cuta a kai a kai:

- aƙalla lokaci 1 a cikin shekara a cikin marasa lafiya da keɓaɓɓen aikin koda,

- aƙalla sau 2-4 a shekara a cikin marasa lafiya tare da taro na serin creatinine kusa da VGN, haka kuma a cikin tsofaffi marasa lafiya.

Yakamata a yi taka tsantsan yayin da akwai haɗarin aiki na nakasassu, alal misali, lokacin da ake rubuta maganin rigakafi ko diuretics, a farkon maganin NSAID. Jiyya tare da Glibomet ® ya kamata a dakatar da sa'o'i 48 kafin a yi amfani da X-ray tare da iv na wakilai na iodinated kuma a maye gurbinsu da wasu magungunan hypoglycemic (alal misali, insulin).

Yin amfani da miyagun ƙwayoyi Glibomet ® dole ne a dakatar da sa'o'i 48 kafin aikin da aka shirya a ƙarƙashin maganin sa barci, tare da maganin kashin baya ko cutar epidural. Ya kamata a ci gaba da warkarwa bayan komawar abinci na baka ko kuma ba a ɓoye sama da awanni 48 ba bayan tiyata, idan an tabbatar da aikin koda na al'ada.

Ethanol na iya tayar da haɓakar rashin ƙarfi na jini, kazalika da disulfiram-like reaction (tashin zuciya, amai, raɗaɗin ciki, jin zafi a kan fata na fuska da babba, tachycardia, dizziness, ciwon kai), don haka ya kamata ka guji shan giya yayin jiyya tare da Glibomet ®.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

Lokacin ɗaukar miyagun ƙwayoyi Glybomet ®, hypoglycemia na iya haɓaka, kuma, sakamakon hakan, raguwa a cikin ikon tattarawa da saurin psychomotor, sabili da haka, yayin kulawa tare da miyagun ƙwayoyi, yakamata a yi taka tsantsan yayin tuki motocin, abubuwan da ke cikin haɗarin haɗari.

Yawan abin sama da ya kamata

Kwayar cutar yiwuwar lactic acidosis (saboda aikin metformin), hypoglycemia (saboda aikin glibenclamide).

Bayyanar cututtuka na lactic acidosis: rauni mai ƙarfi, raunin ƙwayar tsoka, raunin numfashi, tashin zuciya, tashin zuciya, amai, zawo, ciwon ciki, hauhawar jini, rage karfin jini, reflex bradyarrhythmia, rikicewa da asarar hankali.

Bayyanar cututtukan hypoglycemia: yunwar, gumi mai yawa, rauni, palpitations, pallor na fata, paresthesia a cikin roba, tashin hankali, damuwa na gaba daya, ciwon kai, matsanancin bacci, rashin bacci, yanayin jin tsoro, rashin daidaituwa game da motsi, rikicewar jijiyoyin wucin gadi. Tare da ci gaban hypoglycemia, asarar iko da hankali yana yiwuwa.

Jiyya: idan ana zargin lactic acidosis, ana ba da shawarar cire magunguna da gaggawa asibiti da gaggawa. Mafi kyawun magani shine maganin hemodialysis.

Tare da hypoglycemia mai laushi, ya kamata ku ɗauki wani sukari, abinci ko abin sha mai yawa a cikin carbohydrates (jam, zuma, gilashin shayi mai laushi) a ciki.

Game da asarar hankali, ya zama dole a allurar 40-80 ml iv na maganin 40% na dextrose (glucose), sannan ku samar 5-10% dextrose bayani. Bayan haka zaka iya shigar da 1 mg na glucagon cikin / in, / m ko s / c. Idan mara lafiyar bai sake murmurewa ba, ana ba da shawarar a maimaita wadannan matakan. Idan babu sakamako, an nuna kulawa mai zurfi.

Hulɗa da ƙwayoyi

Tasirin hypoglycemic na miyagun ƙwayoyi Glybomet ® yana haɓaka ta hanyar gudanarwa na lokaci guda na abubuwan coumarin (warfarin, syncumar), beta-blockers, cimetidine, oxytetracycline, allopurinol, inhibitors na MAO, sulfonamides, phenylbutazone, abubuwansa na ambarewar, amloide amide; , miconazole (don gudanar da maganin baka), sulfinpyrazone da ethanol.

Adrenaline, corticosteroids, maganin hana haihuwa, shirye-shiryen hodar iblis, abubuwan thiazide diuretics da barbiturates suna rage tasirin hypoglycemic na miyagun ƙwayoyi Glybomet ®.

Tare da amfani da lokaci guda tare da miyagun ƙwayoyi Glibomet ®, haɓaka tasirin maganin anticoagulants yana yiwuwa.

Amfani da ciki tare da cimetidine na iya ƙara haɗarin lactic acidosis.

Yin amfani da beta-blockers na iya rufe alamun hypoglycemia (ban da yin ɗumi da yawa).

Yin amfani da magungunan radiopaque-iodine wanda ke dauke da kwayoyin cuta (don gudanarwar cikin jijiya) na iya haifar da lalacewar aikin kodan da tarin metformin, wanda ke kara hadarin lactic acidosis.

Alamu don amfanin Glibomet

Ofaya daga cikin ayyukan miyagun ƙwayoyi shine don haɓaka samar da insulin kansa. Wannan mai yiwuwa ne kawai idan mai haƙuri yana da rayayyun ƙwayoyin beta a cikin ƙwayar ƙwayar cuta, don haka an tsara allunan Glibomet kawai tare da nau'in ciwon sukari na 2. Tare da nau'in cuta ta 1, wannan magani ba shi da tasiri.

Alamu don amfani:

Marasa lafiya waɗanda aka nuna don jiyya tare da hadaddun guda biyu (tare da gemoclobin haemoglobin da ya wuce 8%) ko uku (HH> 9%) wakilai na hypoglycemic.
Marasa lafiya waɗanda ke da abinci, motsa jiki, da waɗanda aka riga aka tsara metformin ko glibenclamide ba su ba da raguwar sukari da ya kamata.
Masu ciwon sukari tare da rashin haƙuri zuwa babban allurai na metformin.
Sauya magunguna guda biyu tare da guda a cikin marasa lafiya da ke fama da cutar sankara na dogon lokaci.

Duk allunan maganin antidiabetic na sulfonylurea na iya haifar da hypoglycemia. Glibomet ba togiya. Glibenclamide, wanda shine sashinta, shine magani mafi karfi a cikin wannan rukunin, kuma, sabili da haka, mafi haɗari dangane da cututtukan hypoglycemia.

Marasa lafiya tare da tsinkayar yanayi zuwa saurin sukari ko tare da alamu masu laushi Glybomet suna ƙoƙarin kada su rubuto. Sabbin masu ciwon suga sun fi dacewa da waɗannan masu ciwon sukari.

Abun da kuma maganin yake amfani dashi

Sakamakon magani yana faruwa ne saboda abubuwa masu aiki waɗanda ke cikin abubuwan da ya ƙunsa. Tabletaya daga cikin kwamfutar hannu Glibomet yana ƙunshe da ƙwayoyin 400 na metformin, 2.5 mg na glibenclamide.

Metformin yana aiki akan metabolism metabolism ta hanyar abubuwan da yawa. Babu wani daga cikinsu kai tsaye da ke shafi cutar koda. Metformin yana rage sakin glucose a cikin jini ta hanta, wanda ke taimakawa wajen daidaita sukari mai azumi. Yana haɓaka amsawar sel zuwa insulin, wanda ke inganta yin amfani da glucose ta hanyar kyallen da suke da insulin - tsokoki, mai, da hanta. Tun da metformin baya tasiri sel sel, ba zai haifar da hypoglycemia ba.

Daga cikin ƙarin ayyukan wannan abu, mafi mahimmanci a cikin ciwon sukari mellitus shine tasirin metformin akan iyawar jini don narke ƙwanƙwasa jini da suka fara farawa. Wannan shi ne kawai magani na antidiabetic wanda aka tabbatar don rage haɗarin rikice rikicewar macrovascular a cikin masu ciwon sukari. Metformin yana rage mutuwa da 42%, bugun zuciya ta hanyar 39%.

Aiki na kashi na biyu na Glibomet, glibenclamide, shine inganta asirin insulin. Don yin wannan, yana ɗaure wa masu karɓa na beta-cell kuma, kamar glucose, yana ƙarfafa aikin su. A cikin rukunin kungiyarsa, glibenclamide shine mafi kyawun magani don tasirin hypoglycemic. Hakanan yana da ikon ƙara yawan ɗakunan glycogen a cikin ƙwayar tsoka. A cewar likitocin, shan glibenclamide a cikin marasa lafiya da isasshen ƙira na insulin na iya inganta hanyar ciwon sukari da rage yawan rikicewar ƙwayoyin cuta ta 25%.

Don haka, ƙwayar cutar Glybomet tana shafar manyan abubuwan da ke haifar da hauhawar jini: ta dawo da isasshen samar da insulin kuma tana rage juriya.

Ab Adbuwan amfãni na Glibomet:

sauƙi na amfani. Maimakon Allunan 6, uku sun isa,
rage yawan sukari kafin da kuma bayan cin abinci,
da ikon rage kashi zuwa allunan 1-2 idan an samu biyan diyya,
ƙarin aiki - haɓaka bayanin martaba na jini, rage nauyi, rage karfin jini,
rage yunwa. Dangane da masu ciwon sukari, wannan tasirin yana baka damar samun nasarar ci gaba da tsarin abincin,
kasancewa - Ana iya siyan glybomet a kusan kowane kantin magani a farashi mai araha. Jiyya tare da kwayoyi guda biyu da ke da iri ɗaya, misali Maninil da Siofor, za su fi tsada fiye da ɗaukar Glibomet.

Yadda ake ɗauka

Rage sukari bayan shan Glibomet yana farawa a cikin awanni 2 kuma yana ɗaukar tsawon awanni 12, don haka umarnin yin amfani da shawarar yana bada shawarar shan maganin sau biyu a rana. Sha kwaya tare da abinci.

Sashin maganin yana ƙaddara ta hanyar endocrinologist. A wannan yanayin, matakin glucose, shekaru, nauyi na mai haƙuri, abincinsa, halayyar hypoglycemia ya kamata a la'akari da shi.

Yadda za a zabi madaidaicin sashi:

Fara amfani da allunan 1-3. A mafi girma da glycemia, da more Allunan ake bukata. Idan mara lafiya bai taɓa shan magani tare da kayan aiki masu aiki iri ɗaya ba, zai fi aminci idan aka fara da kwamfutar hannu 1. Masu ciwon sukari da basu dauki metformin a baya ba kuma suna shan kwamfutar hannu 1 na farkon makonni 2 na farko. Wannan abun yakan haifar da rashin jin daɗi a cikin narkewa. Don amfani dashi, jiki yakan ɗauki ɗan lokaci.
Theara yawan magunguna tare da isasshen diyya don ciwon sukari na iya zama kowace kwana 3. Tare da rashin haƙuri na metformin - kowane mako 2.
Matsakaicin adadin yau da kullun bisa ga umarnin shi ne allunan 5. Wucewa yana iya haifar da yawan zubar jini da hauhawar jini. Idan allunan 5 basu isa ba don rama don ciwon sukari, ana inganta magani tare da kwayoyi daga wasu rukuni.

Yawan metformin a Glibomet yana da ɗan ƙarami. A daidaitaccen maganin yau da kullun na allunan 4, masu ciwon sukari suna karɓar nauyin 1600 na metformin, yayin da mafi kyawun ƙwayar cuta shine 2000 kuma mafi girman shine 3000 MG. Idan mai haƙuri da ciwon sukari yana nuna kiba ta ciki, ba zai yiwu ba ko kuma rashin haƙuri na ƙoshin jiki, ƙoshin insulin mai ƙarfi, ƙwayar hawan jini, yana ba da shawarar shan magungunan metformin kafin lokacin kwanciya.

Side effects da yawan abin sama da ya kamata

Daga cikin sakamako masu illa na miyagun ƙwayoyi Glibomet, mafi yawan abubuwa shine hypoglycemia, wanda za'a iya haɗuwa da shi har zuwa hauhawar jini na hypoglycemic. Babban bangare na hypoglycemia shine huhu, da ke buƙatar ƙaramar saƙo daga mai haƙuri tare da ciwon sukari. Dalilin raguwar sukari na iya zama wuce haddi na Glibomet, cin zarafin abinci, wuce gona da iri ko aikin da ba'a shirya ba.

Yawan abin sama da ya kamata na iya haifar da matsananciyar matsalar cutar sankara - lactic acidosis. Yawancin lokaci, ana buƙatar abubuwan haɗin kai don haɓakawarsa: cututtuka na kodan, hanta, gabobin numfashi, anemia, da dai sauransu.

Jerin yiwuwar sakamako masu illa dangane da umarnin:

Zalunci	Kwayar cutar	Informationarin Bayani
Hypoglycemia	Girgiza kai, ciwon kai, matsananciyar yunwar, palpitations.	Don kawar da buƙatar gudanar da maganin baka na 15 g na glucose (ruwan 'ya'yan itace, cube sukari, shayi mai zaki).
Matsalar narkewa	Rage, rashin cin abinci, ɗanɗano a cikin bakin, zawo.	Wadannan bayyanar cututtuka ana haifar da su ta hanyar metformin. Za a iya guje musu ta hanyar ƙara yawan sashi, kamar yadda aka bayyana a sama. Dangane da sake dubawa, a cikin yawancin masu ciwon sukari, raunin narkewa ya ɓace bayan makonni 2 na shan Glibomet.
Rashin aikin hanta	Hepatitis, ƙara yawan aiki na enzymes ALT, AST.	Fitowar irin wannan sakamako na iya buƙatar dakatar da magani. A wannan yanayin, canje-canje na cututtukan cuta sun ɓace akan nasu, mafi yawan lokuta basa buƙatar magani.
Canja jini a cikin jini	Babu rashi. A cikin gwajin jini - raguwa a yawan adadin leukocytes da platelet, anemia.
Allergy da hypersensitivity ga abubuwan da ke cikin miyagun ƙwayoyi Glibomet	Fata na ƙaiƙayi, farji, zazzabi, ciwon haɗin gwiwa.	Allergies zai iya haifar da aiki da tsofaffi a cikin kwamfutar hannu. Idan amsawar anaphylactic ta faru, an soke maganin.
Lactic acidosis	Rashin rauni, jin zafi a cikin sternum, tsokoki, murjiyoyin tsoka, amai, zafin ciki.	Halin yana da haɗari tare da lactic acidotic coma, yana buƙatar shafewar Glibomet da kira na gaggawa zuwa likita.
Barasa maye	Aka maimaita alamun alamun maye: maye, amai, ciwon kai, shanyewar jini, hawan jini.	Zai iya faruwa yayin shan Glibomet da barasa. Ga masu ciwon sukari da ke shan maganin, koyarwar ta ba da shawarar barin giya.

Hadarin illa da ba a ke so ba, ban da hypoglycemia, ana tantance shi ta hanyar yin amfani da shi a matsayin wanda ba kasafai ba ne (kasa da 0.1%) kuma da wuya sosai (ƙasa da 0.01%).

Analogs da wasu abubuwa

Analogs na Glibomet tare da guda ɗaya na abubuwan aiki (2.5 + 400) - Gluconorm na Indiya da Metglib na Rasha. Duk sauran haɗuwa na glibenclamide tare da metformin suna da digo na 2.5 + 500 da 5 + 500, don haka lokacin da kuka sauya zuwa waɗannan magungunan, sukarinku na yau da kullun na iya canzawa. Zai yiwu, ana buƙatar daidaita sashi.

Analogues a Rasha an samar da manyan kamfanonin magunguna 4 - Pharmasintez, Pharmstandart, Kanonfarma da Valeant. Dangane da sake dubawa, magungunan su suna da tasiri kamar Glibomet.

Kungiyar magunguna	Suna	Kasar samarwa	Mai masana'anta
Cikakkun analogues, hadewar metformin da glibenclamide	Glibenfage	Rasha	Pharmynthesis
	Karin Gluconorm da		Magunguna
	Forcearfin Metglib		Canonpharma
	Metglib		Canonpharma
	Bagomet Plus		Mai karfi
	Glucovans	Faransa	Merk
	Gluconorm	Indiya	MJ Biopharm
Allunan Glibenclamide	Statiglin	Rasha	Pharmynthesis
	Glibenclamide	Rasha	Atoll, Moskhimpharmprep-t, Pharmstandard, Biosynthesis
	Maninil	Jamus	Barcelona Chemie
	Glimidstad	Jamus	Stad
Shirye-shiryen Metformin	Metformin	Rasha	Gideon Richter, Medisorb, Canon Pharma
	Merifatin		Pharmynthesis
	Tsarin tsayi		Magunguna
	Glucophage	Faransa	Merk
	Siofor	Jamus	Barcelona Chemie
Analogs na tushen aiki, metformin + sulfonylurea	Glimecomb, Gliclazide + Metformin	Rasha	Ahrikhin
Analogs na tushen aiki, metformin + sulfonylurea	Amaryl, glimepiride + metformin	Faransa	Sanofi

Idan magungunan haɗuwa ba a cikin kantin magani ba, ana iya maye gurbin shi da metformin da glibenclamide a cikin allunan daban. Idan kun sha maganin iri ɗaya, rama don ciwon sukari bazai shuɗe ba.

Glimecomb da Amaril suna kusa da Glibomet ta hanyar aikin. Abubuwan da ke aiki da aka haɗa cikin abubuwan haɗin su, gliclazide da glimepiride, sune analogues na glibenclamide. Suna rage sukari kadan kadan, amma sunada aminci ga sel.

Dokokin Ma'aji da Kudinsa

Glybomet yana kiyaye tasiri na shekaru 3, buƙatar ajiya kawai shine yawan zafin jiki wanda bai wuce 30 ° C ba.

Shirya Glibomet daga Allunan 40 yana kashe 280-350 rubles. Mai rahusa analogues sune Gluconorm Plus (farashi 150 rubles don allunan 30), Gluconorm (220 rubles don allunan 40), Metglib (210 rubles don 40 inji mai kwakwalwa).

Glibomet analogues

Lactic acidosis cuta ce mai wuya kuma mai haɗarin rayuwa wanda ke tattare da haɗarin lactic acid a cikin jini, wanda mai yiwuwa ya haifar da tarin metformin.

Abubuwan da aka bayyana game da haɓakar lactic acidosis a cikin marasa lafiya da ke karɓar metformin an lura da su musamman a cikin marasa lafiya da ke fama da ciwon sukari tare da mummunan bugun zuciya da gazawar koda.

Yin rigakafin lactic acidosis ya ƙunshi gano duk abubuwan haɗari masu haɗari, irin su ƙonewar ƙwayar cuta ta hanji, ketosis, yin azumi mai yawan gaske, yawan shan barasa, gazawar hanta da duk wani yanayin da ke tattare da hypoxia.

Lokacin shan magani na Glybomet®, ya kamata a kula da abubuwan da ke cikin ƙwayoyin ƙwayoyin cuta a kai a kai:

aƙalla 1 lokaci a shekara a cikin marasa lafiya da keɓaɓɓen aikin koda,
aƙalla sau 2-4 a shekara a cikin marasa lafiya tare da taro na serin creatinine kusa da VGN, haka kuma a cikin tsofaffi marasa lafiya.

Yakamata a yi taka tsantsan yayin da akwai haɗarin aiki na nakasassu, alal misali, lokacin da ake rubuta maganin rigakafi ko diuretics, a farkon maganin NSAID.

Jiyya tare da Glibomet® ya kamata a dakatar da sa'o'i 48 kafin a yi amfani da X-ray tare da iv na wakilai na iodinated kuma a maye gurbinsu da wasu magungunan hypoglycemic (alal misali, insulin).

Yin amfani da miyagun ƙwayoyi Glybomet® dole ne a dakatar da sa'o'i 48 kafin aikin da aka shirya a ƙarƙashin maganin sa barci, tare da maganin kashin baya ko na maganin tashin hankali. Ya kamata a ci gaba da warkarwa bayan komawar abinci na baka ko kuma ba a ɓoye sama da awanni 48 ba bayan tiyata, idan an tabbatar da aikin koda na al'ada.

Ethanol na iya tayar da haɓakar hypoglycemia, kazalika da disulfiram-like reaction (tashin zuciya, amai, raɗaɗin ciki, jin zafi a kan fata na fuska da babba, tachycardia, dizziness, ciwon kai), don haka ya kamata ka guji shan giya yayin jiyya tare da Glibomet®.

Tasiri kan iya tuka motocin da sauran hanyoyin da ke buƙatar jan hankali sosai

Lokacin ɗaukar Glibomet®, hypoglycemia na iya haɓaka, kuma, sakamakon haka, raguwa a cikin ikon tattarawa da saurin psychomotor, sabili da haka, yakamata a yi taka tsantsan yayin lura da miyagun ƙwayoyi lokacin tuki motocin, abubuwan da ke cikin haɗari mai haɗari.

Glybomet: umarnin don amfani, farashi, sake dubawa da kuma alamun analogues

Lokacin da rage cin abinci don ciwon sukari ba shi da tasiri, likita sau da yawa ya ba da umarnin ɗaukar allunan da ke ɗauke da metformin ko glibenclamide.

Kuma waɗanda ke ɗauke da waɗannan abubuwan suna amintattu musamman. Glybomet yana nufin waɗannan, idan kun bi umarni a fili don amfani da kuma alƙawarin ƙwararren masanin ilimin endocrinologist.

Wannan maganin yana da kaddarorin da yawa waɗanda yakamata a yi la’akari da su daki-daki.

Side effects

Akwai maganganu da yawa yayin shan magani:

Hypoglycemia.
Lactic acidosis.
Ciwon hanci, amai, “ƙarfe” ɗanɗano a bakin.
Ciwon kai.
Karyawance
Abubuwan da suka shafi fata, itching, urticaria.
Bayyanar cututtuka na guba abinci yayin shan tare da barasa.

Kwatanta tare da analogues

Wannan miyagun ƙwayoyi yana da sanannun analogues. Ya kamata a yi la'akari dasu don kwatantawa da Glybomet da kayanta.

Abunda yake aiki shine metformin hydrochloride.

Farashin ya fara daga 130 rubles don guda 30.

Kamfanin Kamfanin Merck Sante ne a Faransa.

Ya kasance cikin aji na biguanides, yana da tasirin hypoglycemic. Ba ya haifar da hypoglycemia, amma yana da arha.

Babban debewa - akwai wasu sakamako masu illa da ban sha'awa (masu juna biyu, tsofaffi, yara). Bai dace da barasa ba.

Abunda yake aiki shine gliclazide.

Wadannan kwayoyin suna farawa daga 300 rubles.

Production - Servier, Faransa.

Yana rage sukarin jini, yana da karamin sakamako masu illa. Babban debewa shine farashin.

Babban abubuwan gyara sune metformin da vildagliptin.

Farashi - daga 1500 rubles (guda 30 kowane).

Kamfanin Novartis ke Switzerland.

Dangane da kayanta, wannan shine mafi dadewa magani (har zuwa awanni 24) daidai da godiya ga haɗuwar abubuwa. Babban hasara shine babban farashi da buƙatar yin oda a cikin kantin magani, kazalika da kasancewar ɗimbin halayen masu haɗari.

Kamar Glibomet, magani ne hade.

Farashin shine 200 rubles don allunan 30.

Kamfanin samarwa Merck Sante, Faransa.

Godiya ga bangarorin guda biyu, magani ne ingantacce, amma kuma yana da layi biyu na sakamako masu illa. Dukkanin hani akan aikace-aikacen sun zo daidai da waɗanda Glibomet ya nuna.

Abun da ya kama, abubuwa guda biyu masu aiki.

Kudin daga 200 rubles (allunan 40).

An samar da "MJ Biopharm", Indiya.

Dukkan kaddarorin sun yi daidai da waɗanda Glibomet ya ƙayyade. Daga cikin fa'idodin, za a iya lura da ƙaramin farashi.

Abubuwan da ke aiki sun yi kama da Glucofage.

Farashin ya bambanta daga ruble 120 (guda 30).

Mai gabatarwa - "Gideon Richter", Hungary, "Teva", Isra'ila, "Canonfarma", Rasha, "Ozone", Russia.

Wannan wakili ne mai dadewa tare da tasirin rage sukari. Akwai shi a aikace, yana da inganci a cikin kaddarorin, amma yana da raunin halaye kuma an haramta shi ga yara da mata masu juna biyu.

Allunan-glibenide tare da dukiyar rage darajar sukari a jiki.

Farashin shine rubles 120 (Allunan 120).

Berlin Chemie, Jamus ne ya samar.

Babban ƙari shine saurin aiki. Amma zai iya haifar da cutar rashin haihuwa, an kuma haramta wa mata masu juna biyu da yara. Ana iya haɗe shi da wasu kwayoyi.

Akwai duka ra'ayoyi masu kyau da mara kyau game da masu ciwon sukari game da wannan magani. An lura da haɓakar ƙarancin sakamako masu illa, musamman idan ana bin hanyoyin maganin abinci.

Victoria: “Na kasance ina shan Glucophage. Amma a hankali sukari ya daina faduwa. Likitan ya ba da shawarar "Glibomet". Sakamakon yana da ban mamaki, amma akwai ƙananan sakamako masu illa. Kodayake idan na bi tsarin abinci, to komai na tsari ne. "

Dmitry: “Na gwada nau'ikan jiyya. Kuma motsa jiki tare da abinci, kuma ku sha kwayoyi. Har zuwa yanzu, mafi kyawun zaɓi shine Glibomet.Hankin sukari ya tabbata, amma yana jin daɗi. Ari, cholesterol ya zama ƙasa. Ba na murna da gaske. "

Daria: “Mama ta kamu da ciwon sukari. Abincin ya juya ya zama mara amfani, saboda haka, an haɗa magunguna. Bayan duk sauran sun gwada, Glibomet ne mafi kyau. Tana jin jiki, kuma matakan glucose koyaushe ɗaya ne. Sai kawai lokacin da zaƙi ya ƙyale, ana samun sakamako masu illa. "

Glybomet: umarnin don amfani, farashi, sake dubawa, analogues

Sau da yawa a cikin lura da nau'in ciwon sukari na 2 na sukari, bai isa ba a yi amfani da ɗayan jagorori biyu kawai na allunan rage sukari. Dole ne a kara Biguanides da mataimakin a jiyya tare da abubuwan da suka samo asali na sulfonylurea.

Magunguna sun sami damar kirkiro magungunan Glibomet, wanda yake shine nasarar hadewar rukuni biyu kuma bisa fahimta, godiya ga hanyoyi daban-daban na fallasa, yana magance matsalolin mutanen da ke fama da wannan cutar.

Aikace-aikacen

Magungunan Glibomet an yi niyya don daidaita matakan sukari a cikin marasa lafiya da ke fama da ciwon sukari na 2, wanda yunƙurin kawo sukari zuwa al'ada tare da maganin rage cin abinci, ɗaukar abubuwan da ake buƙata na sulfonylurea ko biguanides bai yi nasara ba.

Abun da miyagun ƙwayoyi ya ƙunshi abubuwa masu aiki guda 2:

glibenclamide 2.5 MG - wakilin ƙarni na biyu na abubuwan samo asali na sulfonylurea,
Metformin 400 mg shine asalin biguanides.

Tablet-forming taro ana wakilta shi da daidaitaccen rukuni na masana.

A saman allunan an lullube su da wani talc tare da ƙara ɗayan nau'ikan cellulose da diethyl phthalate.

Yin hulɗa tare da wasu magunguna

Yin hulɗa tare da adadin kwayoyi yana haifar da karuwa a cikin tasirin hypoglycemic. Wadannan sun hada da:

coumarin shirye-shirye,
Salamamalla
masu hana beta
sulfonamides,
MAO masu hanawa
miconazole
barasa ethyl

Glibomet yana ƙaruwa da tasirin maganin anticoagulants.

Sakamakon akasin cutarwar jini shine:

glucocorticoids,
maganin hana haihuwa
diuretics na jerin thiazine,
barbiturates
adrenaline
cututtukan mahaifa.

Beta blockers suna haifar da bayyanar cututtuka na hypoglycemia, wanda zai iya zama haɗari ga masu ciwon sukari.

Iodine-bambanci wakilai allura a cikin jijiya taimaka wa tarawar metformin, sabili da haka akwai barazanar lactic acidosis.

Akwai alamomi na Glibamet a cikin aiki da kuma kayan aiki.

Glucovans wani shiri ne wanda aka kirkira don aiwatar da aikin hypoglycemic, wanda kamfanin Merck, Faransa suka kera. Allunan da suka qunshi glibenclamide da metformin a cikin buhunan bakin ciki na allunan 15. A cikin kunshin 2 ko 4 murhun.
Metglib - yana da nau'ikan abun da ke ciki, allunan 40 guda a kowane fakitin.
Bagomet-da - abubuwa guda 2 masu aiki iri ɗaya, amma sashi ya ɗan bambanta. A cikin kunshin 30 Allunan. Argentina Manufacturer.
Gluconorm - hade ne guda biyu, guda 40 kowane, ana samarwa daga Indiya.
Glibomet analogues wanda ya bambanta cikin kayan amma masu kama a aikace sun hada da:
Amaryl ya dogara da glimepiride 1.2.3.4 MG a cikin blisters na guda 15, a cikin kunshin 2, 4, 6 ko 8 fitsarin. Akwai shi a Jamus.
Maninil da Diabeton - sun dogara da glibenclamide, sune abubuwan gado na 2 na ƙarni na sulfonurea.
Maninil - allunan 1.75 MG, 3.5 MG da 5 MG na guda 120. Mai kera - Berlin-Chemie, Jamus.
Diabeton MV - 30 ko allunan 60 na allunan 60 ko 30 Allunan, bi da bi. Servier Laboratory, Faransa mai ba da magani.

A kwatankwacin, Maninil - Diabeton ya kamata a ba shi zaɓi ga Diabeton, a matsayin magani mara ƙarancin cuta.

A farashin, Glybomet da misalansa suna cikin kusan wannan kewayon.

Matsakaicin farashin Glibomed yana daga 200 zuwa 300 rubles.
Glucovans - Farashin yana cikin kewayon 250 - 350 rubles.
Ana sayar da Bagomet-da akan 225 -235 rubles.
Ana iya siyan Metglib akan matsakaici don 230 rubles.
Maninil yana da nauyin 130 -170 rubles.
Ciwon sukari tsakanin iyakokin 159 - 202 rubles.
Farashin Amaryl daga 150 zuwa 3400 rubles. Ana siyar da Amaryl a mafi girma a farashi mafi girma na 4 MG na Allunan 90.

Yana da mahimmanci a san ra'ayoyin masu ciwon sukari akan Glibomet.

***** ta ba da rahoton cewa bisa ga asalin shan Glibomet, koyaushe yana jin ɗanɗano mai ƙarfe a bakinsa, har ma yana da cokali na katako, amma wannan bai taimaka ba kuma an tilasta shi ya ƙi ɗaukar Glibomet. http://diabethelp.org/lechim/glibomet-otzyvy-diabetikov.html

Lotov Roman Andreevich yana ɗaukar Glibomet 25 da safe da maraice, a sakamakon haka, sukari ba ya wuce 4-6 mmol. Gamsu da sakamakon. http://zhivizdorovim.ru/lekarstva/pishchevaritelnyi-trakt/10280-glibomet.html

Irina ta raba cewa bayan shan Glibomet mijinta ya lalace da amai a cikin mako, amma mafi muni shine, sukarin ya tashi daga 10 zuwa 17. http://www.medsovet.info/herb/4279

Ra'ayoyin endocrinologists game da batun sake duba Glybomet galibi tabbatacce ne. Mutane da yawa sunyi imanin cewa zaɓin madaidaiciyar zaɓi yana buƙatar lokaci don kulawa da mai haƙuri da sauri kuma don matakan sukari, ƙila ba za a sami sakamako mai kyau ba daga allurai na farko.

Marasa lafiya yana buƙatar fahimtar cewa kusancin haɗin gwiwa tare da likita, bin ka'idodin shan magani, rage cin abinci, abinci da motsa jiki na yau da kullun sune mahimmancin halin rayuwa wanda ya dogara da ingancin rayuwarsa.

Adana ko raba:

Glibomet: sake dubawa game da masu ciwon sukari, farashi da kuma alamun kwayoyi

Yawancin marasa lafiya waɗanda ke fuskantar matsalar ciwon sukari suna da sha'awar abin da magani zai iya taimakawa sosai ga tsarin kulawa da cutar.

Ofaya daga cikin mafi inganci shine ƙwayar cuta ta Glibomet, wanda ke da kyakkyawan tasirin rage sukari, saboda gaskiyar cewa ya ƙunshi abubuwa kamar metformin da glibenclamide. Matsakaici tsakanin manyan abubuwan da ke cikin miyagun ƙwayoyi glibenclamide da metformin sune 400 mg da 2.5 mg, bi da bi. Kayan aiki ya ƙunshi kayan taimako.

Gaskiya ne, don haɓaka tasirin warkewa, kuna buƙatar fahimtar yadda ake ɗaukar magungunan daidai.

Ana amfani da miyagun ƙwayoyi na musamman a cikin nau'ikan allunan, kunshin ya ƙunshi allunan 40, 60 da 100.

Yana da mahimmanci a lura - ana ɗaukar magani don nau'in ciwon sukari na 2. Babban abu mai aiki, wanda yake wani sashi ne, yana da tasirin motsa jiki a cikin narkewar insulin, yana kara girman tsinkaye na wannan hormone a cikin jiki.

Yana da mahimmanci cewa Glibomet da analogues na wannan magani ana ɗaukar su wani sabon ƙarni na magunguna, saboda amfani da ɗayan manyan abubuwan aiki - glibenclamide. Glibenclamide asalinsa ne na sabon, ƙarni na biyu na sulfonylurea.

Analogues na wannan magani suna da tasiri iri ɗaya akan jiki kuma suna da irin kaddarorin. Glucophage na iya zama magani na analog; ya ƙunshi glibenclamide da metformin.

Babban fa'idar maganin shine magani ne da aka dade ana amfani dashi, ana yin sa ne akan matasa da yara.

Godiya ga nasarar haɗin haɗakar abubuwa biyu, sakamakon shan glibenclamide da metformin, yana yiwuwa a sami kyakkyawan tasirin rage sukari da cin nasara mai yawa. Matsalar yawan kiba mai yawa yakan kasance yana gudana tare da nau'in ciwon sukari na 2.

Menene mahimmanci don tuna lokacin amfani da glibomet?

Kafin ka fara amfani da Glibomet na miyagun ƙwayoyi, yakamata a yi nazarin umarnin dalla-dalla, kana buƙatar karanta hoton kunshin magungunan don fahimtar daidai ko an sayo maganin.

Kasancewar cututtukan concomitant kuma suna taka muhimmiyar rawa. Idan akwai matsaloli tare da hanta, to kuna buƙatar yin hankali lokacin da aka tsara magani.

Zai fi kyau a wannan yanayin koyaushe ɗaukar kwayoyi a layi daya waɗanda ke tallafa wa aikin hanta kanta, alal misali, Essentiale forte. Haka kuma, ma'amala da wannan magani tare da hypoglycemic hakika tabbatacce ne.

Hakanan za'a iya ba da shawara guda ɗaya game da tsarin kulawa, wanda ya ba da shawara cewa kuna buƙatar ɗaukar glucophage.

Akwai magunguna da yawa waɗanda Maninil ke ciki. Sabili da haka, koyaushe zaka iya zaɓar mafi kyawun aikin jiyya don wani haƙuri.

Wasu marasa lafiya suna tunanin cewa Glucophage da Glybomet kalmomin juna ne. Amma wannan kuskure ne, waɗannan magunguna biyu ne daban-daban, kodayake akwai kamanni da yawa a tsakanin su. Haka kuma, duka a hade kuma cikin sharuddan tasirin jiki.

Wadanne magungunan cututtukan cututtukan cututtukan ƙwayar cuta ne suka fi tasiri a cikin bidiyon wannan labarin.

Nuna sukari ko zaɓi jinsi don shawarwari Bincike ba'a samo ba Bincike ba'a samo ba

Magungunan ƙwayar cutar ƙwayar jini na rukuni na biyu Glybomet

Kimanin 6% na yawan mutanen duniya a yau suna fama da ciwon sukari mellitus - wata cuta wacce babbar alama ce karuwar sukarin jini. Abubuwan da ke waje suna tasiri ga ci gaban cutar; ƙwayoyin cuta kuma suna taka rawa.

Mafi kyawun warkarwa ga masu ciwon sukari shine tsarin abinci mai ƙarancin carb: idan mutum na yau da kullun zai iya cin abinci har zuwa 400 g na carbohydrates tsarkakakku a kowace rana, to, ciwon sukari ya ƙasa da g 85

Amma har ma tare da kin amincewa da hatsi, dankali, kayan lambu, yawancin kayan lambu da 'ya'yan itatuwa da maye gurbinsu da kifayen dabbobi da ba sa ƙara yawan glucometer, ba kowa ba ne ke iya rama glycemia gaba ɗaya. Gaskiya ne gaskiyar ga masu ciwon sukari masu nau'in cuta na biyu, wanda tarihin tarihin rashin cin nasara na yara.

Don lura da ciwon sukari, an tsara nau'ikan magunguna 4, waɗanda aka rarrabe su ta hanyar da tsarin tasiri.

Magungunan da ke rage darajar jurewar insulin na sel shine biguanides (Metformin, Glucofage) da thiazolidinediones (Pioglitazone, Rosiglitazone).
Kwayar halittar Pancreatic da ke tattare da sinadarin endogenous shine asalin abubuwan sulfanylureas (Diabeton, Maninil) da yumbu.
Magunguna na jerin abubuwan ɓoye, sarrafa nauyi da ci - Galvus, Januvia, Onglisa, Viktoza, Bayeta.
Magungunan da ke hana shan glucose a cikin hanji sune Acarbose, Glucobay.

Hakanan ana magana game da glybomet zuwa shirye-shiryen maganganu na magana na rukunin rukuni na biyu, umarnin don amfani da wanda za'a gabatar dashi don bita. Ana ɗaukar duk bayanan daga hanyoyin da ke bayyane a bayyane, don haka ba kayan aiki bane don gano kansa da magani na kai.

Ciwon sukari mellitus cuta ce ta tsawon rayuwa tare da rikice-rikicen rayuwa, da kuma gwaje-gwajen da magunguna ba tare da tuntubar mahaukacin endocrinologist da babban bincike ba a yarda da su.

Glybomet - abun da ke ciki

Haɗuwa a cikin kowane kwamfutar hannu na abubuwa biyu masu aiki - metformin hydrochloride (400 MG) da glibenclamide (2.5 MG) ya sa ya yiwu ba kawai don sarrafa glycemia ba, har ma don rage yawan waɗannan abubuwan. Idan kowannensu an yi amfani da shi don maganin tauhidi, to maganin zai zama mafi girma.

Ya ƙunshi tsari da tsofaffi a cikin tsari na cellulose, sitaci masara, colloidal silicon dioxide, gelatin, glycerol, talc, magnesium stearate, acetylphthalyl cellulose, celethlose diethyl.

Abubuwan da ke tattare da magunguna

Ofaya daga cikin manyan abubuwan da ke aiki, glibenclamide, magani ne na sabon ƙarni na sulfonylurea aji, wanda aka haɗo shi cikin jerin mahimman kwayoyi tare da ƙwaƙwalwar ƙwayar cuta da kuma karin-pancreatic.

Bawai kawai yana ƙarfafa aikin koda ba a matsayin gabaɗaya, har ma yana haɓaka aikin samar da insulin ƙwayoyin cuta. Hanyar ayyukansu suna dogara ne da kariyar ƙwayoyin β-sel da ke lalata ta hanyar glucose mai ƙarfi, wanda ke ƙayyade ci gaban ciwon sukari, da ƙarfafa haɓakar insulin ƙwayoyin sel.

Shan Glibomet a layi daya tare da sarrafa glycemic yana inganta haɓakar lipid kuma yana rage haɗarin haɗarin jini. Ayyukan insulin yana ƙaruwa, kuma tare da shi ɗaukar glucose ta kyallen tsoka da hanta. Magungunan yana aiki a mataki na biyu na samar da insulin.

Metformin yana cikin biguanides - wani ɓangare na abubuwa masu karfafawa wanda ke rage ƙarancin ƙwayoyin makafi zuwa insulin nasu. Sake dawo da hankalin mutum ba shi da mahimmanci fiye da haɓakar ruɗar hormone, saboda tare da nau'in ciwon sukari na 2, ƙwaƙwalwar ƙwayar cuta ta haifar da ita har ma da wuce kima.

Metformin yana haɓaka lambar sadarwar masu karɓa da insulin, yana ƙaruwa da tasirin aikin hormone. Idan babu insulin a cikin jini, ba a bayyana tasirin warkewa ba.

Metformin yana da fasali na musamman:

Yana rage jinkirin shan glucose ta bangon hanji da taimaka amfani dashi wajen kyallen takarda,
Yana hana gluconeogenesis,
Yana kare-cell daga hanzarin apoptosis,
Yana rage haɗarin kowane nau'in acidosis da mummunan cututtuka,
Inganta microcirculation na ruwa, aikin endothelial da mai metabolism (yana rage haduwar "cholesterol" mai guba da triglycerol a cikin jini),
Gudanar da asarar nauyi - muhimmin yanayi don ingantaccen iko na sarrafa glycemic a nau'in 2 DS,
Yana rage yawan jini da damuwa da damuwa,
Yana da tasirin fibrinolytic ta hanyar hana mai kunna plasminogen mai aiki,
Yana hana ayyukan oncological (gaba ɗaya, ciwon sukari yana ƙara haɗarin cutar oncology da 40%),
Yana rage haɗarin mutuwa daga al'amuran zuciya.

An sake yin gwaje-gwaje na masu ciwon sikila 5800 masu ciwon sukari masu nau'in 2 a kasar Sin. Mahalarta cikin gwajin sun karbi metformin a hade tare da gyare-gyare na rayuwa. A cikin rukuni mai kulawa, masu sa kai kawai sun daidaita salon rayuwarsu. Tsawon watanni 63, a cikin rukunin farko, mutane 7.5 ke mutuwa a cikin mutane 1000 / shekara, a karo na biyu - na watanni 45, daidai da mutane 11.

Gabaɗaya, a cikin rukunin da ke karɓar metformin, yawan mace-mace ya kasance ƙasa da 29.5% fiye da yadda ake sarrafawa, kuma yawan lokutan abubuwan da suka shafi zuciya sun kasance 30-35%.

Magungunan yana fara aiki sa'o'i biyu bayan shigar esophagus, ingancinsa an tsara shi don awanni 12. Metformin baya haifar da barazanar hypoglycemic.

Magungunan tare da babban tushe na shaida, ya wuce ingantaccen gwajin lokaci kuma yana buƙatar ciwon sukari a duk matakan daɗaɗɗar jiyya.