Mene ne Siofor daga kuma wane irin magani ne wannan: tsarin aiki, nau'i na saki da sashi

Sigar tsari - farin alluna mai farin ciki:

Siofor 500: zagaye, biconvex (inji mai kwakwalwa 10. A cikin blisters, a cikin kwali na kwali na 3, 6 ko 12 blisters),
Siofor 850: tare da juna, tare da daraja mai daraja biyu (inji mai kwakwalwa 15. A cikin blisters, a cikin kwali na kwali na 2, 4 ko 8 blisters),
Siofor 1000: kusa, tare da daraja a gefe guda da kuma ɗaukar shimfidar “snap-tab” ɗayan ɗayan (kwalaye 15. A cikin blisters, a cikin kwali na kwali na 2, 4 ko 8 murhun).

Abubuwan da ke aiki da maganin shine metformin hydrochloride, a cikin kwamfutar hannu guda ɗaya ya ƙunshi 500 MG (Siofor 500), 850 mg (Siofor 850) ko 1000 mg (Siofor 1000).

Mahalarta: povidone, hypromellose, magnesium stearate,
Harshen Shell: macrogol 6000, hypromellose, titanium dioxide (E171).

Alamu don amfani

Siofor an yi niyya ne don kula da cututtukan sukari na II na ciwon sukari na II, musamman a cikin marasa lafiya masu kiba tare da motsa jiki marasa inganci da kuma maganin abinci.

Ana iya amfani dashi azaman magani guda ɗaya ko kuma wani ɓangaren ƙwaƙƙwaran magani a haɗe tare da insulin da sauran wakilai na maganin hypoglycemic na bakin.

Sashi da gudanarwa

Ya kamata a sha miyagun ƙwayoyi a baki yayin abinci ko kuma nan da nan bayan.

Bayanin sashi da tsawon lokacin jiyya yana likitan likita ne ya dogara da matakin glucose a cikin jini.

Lokacin gudanar da maganin monotherapy, ana wajabta manya 500 MG 1-2 sau a rana ko 850 MG 1 sau ɗaya kowace rana. Bayan kwanaki 10-15, idan ya cancanta, yawanci yau da kullun yana ƙaruwa zuwa Allunan 3-4 Siofor 500, Allunan 2-3 Siofor 850 MG ko allunan 2 Siofor 1000.

Matsakaicin adadin yau da kullun shine 3000 MG (allunan 6 na 500 MG ko allunan 3 na 1000 MG) a cikin allurai uku.

Lokacin da ake rubuta babban allurai, ana iya maye gurbin allunan 2 na Siofor 500 tare da 1 kwamfutar hannu na Siofor 1000.

Idan an canza mai haƙuri zuwa metformin daga wasu magungunan maganin antidiabetic, ƙarshen an soke shi kuma sun fara shan Siofor a cikin allurai na sama.

A hade tare da insulin (don inganta sarrafa glycemic), ana wajabta Siofor 500 MG sau 1-2 a rana ko 850 MG sau ɗaya a rana. Idan ya cancanta, sau ɗaya a mako ana sannu a hankali ana ƙaruwa zuwa allunan 3-4 Siofor 500, Allunan 2-3 Siofor 850 ko Allunan 2 Siofor 1000. Ana ƙaddara yawan insulin dangane da matakin glucose a cikin jini. Matsakaicin maganin yau da kullun shine 3000 MG a cikin allurai uku.

Lokacin zabar wani kashi, marasa lafiya tsofaffi kuma suna yin la’akari da maida hankali kan ƙwaƙwalwar creatinine a cikin jini. A lokacin jiyya, kimantawa na yau da kullun game da aikin koda ya zama dole.

Yara masu shekaru 10-18 years kuma don monotherapy, kuma a hade tare da insulin, a farkon jiyya an tsara 500 MG ko 850 MG na metformin 1 lokaci a rana. Idan ya cancanta, bayan kwanaki 10-15, ana samun karin kashi a hankali. Matsakaicin adadin yau da kullun shine 2000 MG (allunan 4 na 500 MG ko Allunan 2 na 1000 MG) a cikin kashi 2-3.

Matsakaicin insulin da ake buƙata ya dogara da matakin glucose a cikin jini.

Side effects

Allergic halayen: da wuya sosai - urticaria, itching, hyperemia,
Tsarin mara lafiyar: sau da yawa - ɗanɗanar damuwa,
Harkokin hanta da kuma biliary fili: rabe-raben rahotanni - karuwa mai yawa a cikin ayyukan hepatic transaminases, hepatitis (wuce bayan cire magunguna),
Metabolism: da wuya - lactic acidosis, tare da tsawan amfani - raguwa a cikin yawan ƙwayoyin bitamin B₁₂ da kuma raguwa a cikin haɗuwarsa a cikin jini na jini (yiwuwar wannan amsa yakamata a la'akari lokacin da aka tsara magunguna ga marasa lafiya da cutar megaloblastic),
Tsarin narkewa: rashin ci, ƙarar ƙarfe a bakin, tashin zuciya, amai, ciwon ciki, zawo. Wadannan bayyanar cututtuka sukan faru ne a farkon magani kuma yawanci sukan tafi da kansu. Don hana su, a hankali ya kamata a ƙara yawan kullun, rarraba shi zuwa allurai 2-3, kuma ɗaukar magani tare da abinci ko kuma nan da nan.

Umarni na musamman

Siofor bai maye gurbin abincin abinci da motsa jiki na yau da kullun ba - dole ne a haɗu da waɗannan hanyoyin da ba magunguna ba tare da miyagun ƙwayoyi tare da shawarar da likitan halartar. Dukkanin marasa lafiya yakamata su bi tsarin abinci tare da tataccen carbohydrates a cikin kullun, kuma mutanen da ke da kiba yakamata su sami abincin mai kalori.

Idan kuna zargin ci gaban lactic acidosis, ana buƙatar karɓar maganin kai tsaye da kuma asibiti na gaggawa na haƙuri.

Metformin ya cire ta ta hanyar kodan, don haka kafin a fara jiyya kuma a kai a kai lokacin aiwatar da shi, yakamata a tantance taro da ke cikin kwayoyin halittar jini a cikin jini. Musamman lura ya zama dole idan akwai haɗarin aikin mara nauyi, alal misali, a farkon amfani da diuretics, anti-mai kumburi mai guba ko magungunan antihypertensive.

Idan ya zama tilas a gudanar da gwajin X-ray tare da gudanar da aikin kwantar da hankula game da wakilin bambancin aidin, Siofor na ɗan lokaci (sa'o'i 48 kafin da 48 bayan aikin) ya kamata a maye gurbin shi da wani magani na maganin ɓacin rai. Hakanan dole ne a yi shi yayin da ake rubuta wani aikin tiyata da aka shirya a ƙarƙashin maganin sa barci na gaba ɗaya, tare da maganin sahun ciki da na kashin baya.

Dangane da gwajin asibiti na shekara guda da aka sarrafa, metformin ba ya tasiri ga ci gaba, haɓakawa, da lokacin balaga na yara. Koyaya, babu bayanai game da waɗannan alamomin tare da doguwar jiyya, sabili da haka, yara waɗanda ke karɓar Siofor, musamman a lokacin da ake so (shekaru 10-12), suna buƙatar sa ido na musamman.

Monotherapy tare da Siofor ba ya haifar da hypoglycemia. Tare da magani tare da haɗuwa (a haɗe tare da abubuwan insulin ko abubuwan da aka samo na sulfonylurea) akwai irin wannan damar, sabili da haka, dole ne a yi taka tsantsan.

Siofor, wanda aka yi amfani dashi azaman ƙwayoyi guda ɗaya, ba ya tasiri da sauri na halayen da / ko ikon yin hankali. Lokacin amfani da metformin a matsayin wani ɓangare na rikicewar jiyya, akwai haɗarin haɓaka yanayin hauhawar jini, sabili da haka, ya kamata a yi taka tsantsan lokacin da kake shiga cikin kowane irin haɗari mai haɗari, gami da lokacin tuki motocin.

Hulɗa da ƙwayoyi

Metformin yana contraindicated yayin karatu tare da gudanarwar maganin kwantar da hankali na abubuwan sarrafa aidin.

Ba'a ba da shawarar sha giya ba da shan magungunan ethanol a lokacin magani, tunda haɗarin haɓakar lactic acidosis yana ƙaruwa, musamman tare da lalacewar hanta, rashin abinci mai gina jiki ko cin abinci.

Haɗuwa yana buƙatar taka tsantsan dangane da yiwuwar halayen hulɗa:

Danazole - haɓaka tasirin sakamako,
Angiotensin-mai canza tsofaffin masu hana enzyme da sauran magungunan antihypertensive - suna rage glucose na jini,
Hormones na thyroid, maganin hana haihuwa, acid nicotinic, glucagon, epinephrine, abubuwan halittar phenothiazine - karuwa a cikin tarowar hawan jini,
Nifedipine - ƙara yawan sha da mafi girman maida hankali na metformin a cikin jini, tsawaita daga aikinta,
Cimetidine - rage jinkirin kawar da metformin, yana ƙara haɗarin lactic acidosis,
Salicylates, abubuwan da ake amfani da su na sulfonylurea, insulin, acarbose - karuwar tasirin hypoglycemic,
Magungunan cationic (procainamide, morphine, quinidine, triamteren, ranitidine, vancomycin, amiloride) sun ɓoye a cikin tubules - karuwa a cikin mafi girman taro na metformin a cikin jini,
Furosemide - raguwa a cikin taro da rabin rayuwa,
Kai tsaye anticoagulants - rauni da aikinsu,
Beta-adrenergic agonists, diuretics, glucocorticoids (don amfani da tsari da Topical) - karuwa a cikin glucose jini.