Magungunan Clindamycin: umarnin don amfani

Ana samar da maganin ta hanyar gelatin capsules da ke da shunayya mai launin shuɗi da jan hula. Capsules suna dauke da farar fata ko launin shuɗi. Kowane ƙwayar capsule ya ƙunshi 150 MG na aiki mai aiki na clindamycin a cikin nau'i na hydrochloride.

Ana amfani da Talc, lactose monohydrate, magnesium stearate da sitaci na masara azaman ƙarin kayan haɗin.

Kayan magunguna

Clindamycin yana da tasirin sakamako iri iri kuma cuta ce wacce ke hana aiwatar da aikin furotin a cikin ƙananan ƙwayoyin cuta. Babban bangaren yana aiki da ingantaccen gram-tabbatacce kuma cocci microaerophilic, kazalika da anaerobic gram-tabbataccen bacilli, wanda ba ya haifar da lalata.

Yawancin nau'ikan clostridia suna tsayayya da wannan kwayoyin. A wannan batun, idan mai haƙuri yana da kamuwa da cuta wanda wannan nau'in ya haifar, an ba da shawarar cewa an ƙaddara maganin rigakafi da farko.

Bayan amfani, maganin yana nan da nan a cikin jijiyar. Cin abinci yana rage rage yawan narkewa, amma ba ya tasiri da yawan maganin a cikin jini. Magungunan yana da mummunan aiki ta hanyar katangar-kwakwalwa, amma yana iya shiga kyallen da ruwa kamar huhu, yau, ƙwanƙwalwa, ƙwaƙwalwa, jijiyoyin mahaifa, jijiyoyin ƙwayoyin cuta, ƙwanƙolin hanci, ƙashi da jijiyoyin tsoka, maniyyi, ƙwayar jijiya, ƙwayar bile, prostate gland, jaka. A gaban aiwatar da kumburi a cikin meninges, da permeability na kwayoyin ta hanyar jini-kwakwalwa ƙaru.

Ana lura da mafi girman adadin ƙwayar a cikin jini awa daya bayan amfani da capsules. Babban ɓangaren magungunan an cire shi daga jiki tsawon kwanaki 4 tare da taimakon kodan da hanjinsa.

Alamu don amfani

An wajabta maganin don cututtukan masu zuwa:

• Yin rigakafin kumburin ciki da na ciki bayan fargaba ko raunin hanji,
• Ciwon mara
• Cututtukan cututtuka na kyallen takarda mai laushi da fata (panaritium, ƙurji, raunin da ya kamu, kumburi), haka kuma a cikin rami na ciki da na ciki (ƙurji da peritonitis),
• Cututtukan cututtukan cututtukan jijiyoyin jiki da na jikin ENT (sinusitis, pharyngitis, otitis media da tonsillitis), ƙananan tsarin na numfashi (pleural empyema, pneumonia, bronchitis and abscess in the huhu), diphtheria, scarlet fever,
• Endocarditis na yanayin ƙwayar cuta,
• Osteomyelitis a cikin na kullum ko m mataki,
• Cututtukan cututtukan cututtuka na gabobin tsarin ƙwayar urogenital (hanyoyin ƙwayar kumburi-tubo-ovaria, endometritis, chlamydia, cututtuka na farji),
• Cututtukan cututtuka tare da tsarin kumburi da lalacewa ta hanyar microgenganisms microgenganisms suna da hankali ga ƙwayar clindamycin.

Sakawa lokacin

Capsules na sarrafawa ne na baka. Yawancin lokaci an tsara shi don ɗaukar kashi 150 na MG tare da tazara tsakanin 6 ko 8 hours. Idan mai haƙuri ya sha wahala daga mummunan kamuwa da cuta, ana iya ƙara yawan zuwa 300 ko 450 MG. Lokacin da suke rubuta magungunan ga yara na wata ɗaya masu shekaru, suna yin jagora ta hanyar lissafin 8 ko 25 a kowace kilogiram na nauyin jikin mutum. Yayin rana ya kamata ya zama allurai 3 ko 4.

Yawan abin sama da ya kamata

Lokacin amfani da miyagun ƙwayoyi a cikin sashi na wucewa ta warkewar al'ada, halayen masu illa na iya ƙaruwa.

Idan ya kasance abin karyewa, ana yin magani ne da nufin rage alamun. Ya kamata a ɗauka cewa wannan magani ba shi da maganin rigakafi, kuma dialysis da hemodialysis ba za su sami tasiri mai mahimmanci ba.

Hulɗa da ƙwayoyi

Kwatancen gudanarwa na Gentamicin, streptomycin, aminoglycosides da rifampicin juna suna haɓaka tasiri na magunguna da clindamycin da ke sama.

Tare tare da shakatawa na tsoka mai saurin motsa jiki, shakatawa na tsoka, wanda ke haifar da maganin rashin ƙarfi, na iya ƙaruwa.

Ba za a iya ɗaukar magungunan Clindamycin tare da kwayoyi kamar magnesium sulfate, aminophylline, ampicillin, alli gluconate da barbiturates.

Antagonism an nuna shi dangane da chloramphenicol da erythromycin.

Ba shi da kyau a yi amfani da miyagun ƙwayoyi a haɗaka tare da kwayoyi kamar su phenytoin, hadaddun bitamin B, aminoglycosides.

Tare da yin amfani da layi daya na amfani da magungunan antidiarrheal, da alama cututtukan ƙwayoyin cuta ke ƙaruwa.

Amincewar yin amfani da narcotic (opioid) analgesics na iya kara yawan nakuda na numfashi (tun kafin tashin hankali).

Side effects

Yin amfani da maganin zai iya haifar da bayyanar waɗannan halayen masu illa:

• Tsarin zuciya: jiji da kai, jin rauni,
• Hematopoietic gabobin: thrombocytopenia, neutropenia, leukopenia, agranulocytosis,
• Tsarin narkewa: dysbiosis, raunin aikin hanta, esophagitis, cututtukan ƙwayar cuta na ƙwayar cuta, ƙaruwar bilirubin, jaundice, rikicewar dyspeptic,
• Bayyanar bayyanar cututtuka: eosinophilia, urticaria, bayyanuwar anaphylactoid, dermatitis, pruritus, rash,
• Tsarin Musculoskeletal: wani canji a cikin tsarin jijiyoyin jini,
• Sauran: superinfection.

Contraindications

Bai kamata a sanya maganin a cikin halaye masu zuwa ba:

• Babban hankali ga kowane bangare na miyagun ƙwayoyi,
• Lactation
• A gaban rare hereditary cututtuka,
• Asma yana da baka,
• Shekarun da basu kai shekaru 3 (nauyin jikin yarinyar ba zai zama kasa da kilogiram 25),
• Lokacin haila
• Stitches a gaban wani miki
• Myasthenia gravis

Yakamata a yi taka tsantsan lokacin da aka tsara magunguna ga tsofaffi marassa lafiya, da kuma a gaban ƙwayar koda da gazawar hanta.

Umarni na musamman

Kwayar cuta ta pseudomembranous na iya bayyana duka lokacin jiyya da kuma bayan ƙarshen jiyya. Ana nuna sakamako mai illa ta hanyar zawo, leukocytosis, zazzabi da jin zafi a cikin ciki (a lokuta mafi wuya, feces sun ƙunshi gamsai da jini).

A cikin irin wannan yanayin, ya isa ya soke maganin kuma ya tsara resins-musayar resins a cikin hanyar colestipol da colestyramine. A cikin lokuta masu tsanani na wannan cuta, ya zama dole don ramawa game da asarar ƙwayar cuta, furotin da ƙwayoyin lantarki da kuma sanya metronidazole da vancomycin.

A lokacin jiyya, an contraindicated don wajabta magungunan da ke hana motsin hanji.

Ba a tabbatar da amincin amfani da miyagun ƙwayoyi da maganin Clindamycin a cikin ilimin yara, saboda haka, tare da magani na dogon lokaci a cikin yara, ya kamata a sa ido kan abubuwan da suka shafi jini da yanayin hanta a kai a kai.

Lokacin ɗaukar miyagun ƙwayoyi a babban sashi, kuna buƙatar sarrafa adadin clindamycin a cikin jini.

Marasa lafiya da ke fama da matsanancin hanta ya kamata su sa ido a aikin hanta.

Formaddamar da tsari da abun da ke ciki

Ana samun Clindamycin a cikin waɗannan siffofin:

• Vaginal cream 2% - daga fari tare da mai kirim mai launin shuɗi ko launin shuɗi zuwa fari, tare da ƙanshin ƙanshin ƙanshi (20 g da 40 g a cikin bututun aluminum, bututu 1 kowanne tare da mai nema),
• Gelatin capsules - tare da jan kyalle da shari’ar shunayya, girman No. 1, abubuwan da ke cikin capsules sune foda daga launin fari-fari zuwa fari cikin launi (inji mai kwakwalwa 8. A cikin blisters, blisters 2 a cikin kwali na kwali, guda 6 a cikin fitsari, 2 a kowane, 5 da blister 10 a cikin kwali na fakiti),
• Magani don allura (allura da allura) - m, dan kadan mai launin shuɗi ko mara launi (2 ml cikin ampoules, 5 ampoules a cikin blisters, fakitoci 2 a cikin kwali na kwali).

Tsarin 100 g na kirim na ciki ya hada da:

• Abunda yake aiki: clindamycin (a cikin nau'in phosphate) - 2 g,
• Abubuwan taimako: sodium benzoate, macrogol-1500 (polyethylene oxide-1500), mai Castor, emulsifier A'a 1, propylene glycol.

Abun da ke ciki na capsule 1 ya hada da:

• Abunda yake aiki: clindamycin (a cikin nau'in hydrochloride) - 0.15 g,
• Aka gyara kayan masara: sitaci sitaci, talc, lactose monohydrate, magnesium stearate,
• Abun murfin murfin capsule: dye lu'u-lu'u mai laushi (E151), dioxide dioxide (E171), azorubine dye (E122), quinoline mai launin shuɗi (E104), dintin Ponceau 4R (E124), gelatin,
• Abun da ke cikin jikin kwalliya: fenti mai launin shuɗi (E151), ruwan azorubine (E122), gelatin.

Tsarin 1 ml na mafita don allura ya haɗa da:

• Abubuwa masu aiki: clindamycin (a cikin nau'i na phosphate) - 0.15 g,
• Abubuwan taimako: edetate disodium, benzyl barasa, ruwa don allura.

Sashi da gudanarwa

Don cututtukan cututtuka masu rauni na matsakaici na manya da yara daga shekara 15 (yana yin nauyin kilo 50 ko fiye), an wajabta maganin Clindamycin sau 1 (kwatancin 150) sau 4 a rana a kullun na yau da kullun. A cikin cututtukan da ke cikin raɗaɗi, ana iya ƙara guda ɗaya ta sau 2-3.

Eraramin yara galibi ana umurta:

• Shekaru 8-12 (nauyi - 25-40 kg): cuta mai tsanani - sau 4 a rana, kwalliyar 1, mafi girman kowace rana - 600 MG,
• Shekaru 12-15 (nauyi - 40-50 kilogiram): matsakaicin tsananin cutar shine sau 3 a rana don maganin capsule 1, tsananin cutar shine sau 3 a rana don capsules 2, matsakaicin kullun shine 900 mg.

Yawan shawarar da aka bayar da shawarar manya don gudanar da jijiyar ciki da kwayar cutar ciki shine 300 mg sau 2 a rana. A cikin lura da cututtukan cututtuka masu mahimmanci, ana ba da umarnin 1-2-2.7 g kowace rana, an rarraba shi zuwa injections 3-4. Gudanar da intramuscular na kashi daya na fiye da 600 MG ba a ba da shawarar ba. Matsakaicin ɗayan guda ɗaya don gudanarwa na ciki shine 1.2 g na awa 1.

Ga yara daga shekaru 3, Clindamycin an wajabta shi a cikin kashi 15-25 mg / kg a kowace rana, ya kasu kashi uku na daidaitaccen mulki. A cikin lura da cututtukan cututtuka masu tsanani, ana iya ƙara kashi ɗaya na yau da kullum zuwa 25-40 mg / kg tare da yawan adadin amfani.

A cikin marasa lafiya da mummunan koda ko / gazawar hanta, a cikin yanayin amfani da miyagun ƙwayoyi tare da tazara na akalla awanni 8, ba a buƙatar gyaran tsarin maganin.

Don gudanarwar cikin hanji, clindamycin ya kamata a tsarma zuwa taro wanda ba shi da girman 6 mg / ml. Maganin an allurar dashi na tsawon minti 10-60.

Ba a bada shawarar allura ta ciki ba.

A matsayinka na narkewa, zaka iya amfani da mafita: 0.9% sodium chloride da 5% dextrose. Dilution da tsawon jiko bada shawarar a yi bisa ga makirci (kashi / girma na sauran ƙarfi / tsawon jiko):

• 300 mg / 50 ml / 10 minti
• 600 MG / 100 ml / minti 20
• 900 mg / 150 ml / minti 30
• 1200 mg / 200 ml / 45 minti.

Ana amfani da cream cream din cikin ciki. Cikakken kashi - mai cikakken cream cream (5 g), zai fi dacewa kafin lokacin kwanciya. Yawan amfani shine kwanaki 3-7 kowace rana.