Liraglutide don lura da kiba: umarnin da miyagun ƙwayoyi

Rada tana nufin irin wannan kayan aiki kamar Liraglutid. Ana amfani dashi don sarrafa glucose a cikin jinin masu ciwon sukari. Ana samun mafi yawan maganin a ƙarƙashin sunan Viktoza ko Saksenda.

Liraglutide shine abu mai aiki akan abin da aka kirkira shi. Babban aikin wannan bangaren shine rage yawan sukari a cikin jini.

Yi amfani da samfurin a hankali, tunda yana da tasirin sakamako da kuma contraindications. Kafin wa’adin, likita yayi nazari da kuma nazarin hoton asibiti na cutar. A nan gaba, dole ne a sanya ido kan aikin domin a hana ci gaban hawan jini da sauran rikicewa.

Menene liraglutide

A cikin 2009, ƙwayar liraglutide ta bayyana a Rasha, wanda aka samar a Denmark kuma ana amfani dashi don kula da ciwon sukari ba tare da dogara da insulin ba. Abubuwan da ke cikin asali shine agonist (kwafin) na glucagon-like peptide GLP-1, kusan ba ta bambanta da yanayin ɗan adam na ɗan adam ba, sabili da haka jiki ba shi da wakilcin wakilcin ƙasashen waje.

Tsarin aiki don rasa nauyi

Ana samun kayan aiki a cikin nau'i na sirinji don allurar subcutaneous. Ta hanyar nunawa farji, tana karfafa kwayar insulin kuma yana sauƙaƙa tashin hankali. An gano cewa a cikin rabin marasa lafiya, nauyin ya ragu da 5-10% yayin watan amfani. Yawan kitse da asarar nauyi yana faruwa ne sakamakon hana yunwar da amfani da makamashi. Liraglutide don kula da kiba yana da waɗannan kaddarorin:

• lowers sukari jini
• yana ƙara yawan jikewa da abinci,
• Dangane da sake dubawa, yana hana ci.

Magunguna tare da liraglutide

Gurasar da ke dauke da sinadarin ta kasance reshen kayan maye ne. Babu allunan. Wannan magani Viktoza ne da asalinsa Saksenda (yana da kayan aiki guda ɗaya, amma wani masana'anta ya ƙera shi). Ana amfani da magungunan biyu don magance ciwon sukari, a cikin asarar nauyi a cikin majinyata na manya. An wajabta masu don ƙididdigar taro na jiki sama da 30 ko 27, idan akwai hauhawar jini.

Babban mahimmancin liraglutide shine don taimakawa pancreas a cikin samar da insulin na hormone, ƙarin ƙari shine inganta canjin glucose zuwa makamashi, ba mai mai ba. Alkalami na Victoza sirinji ya ƙunshi sashi mai aiki, wanda aka haɓaka tare da sodium hydrogen phosphate dihydrate, phenol, sodium hydroxide, ruwa da propylene glycol. Syaya daga cikin sirinji ya ƙunshi 3 ml na bayani, matsakaicin farashin kasuwa shine $ 158 ko 9,500 rubles.

Za a iya maye gurbin Victoza don asarar nauyi ta Saxenda, ana samun su ta hanyar alkalami, amma tuni 5 inji mai kwakwalwa. 3 ml na bayani kowane (farashi 27 dubu rubles). Bugu da ƙari, abun da ke ciki ya haɗa da propylene glycol, sodium hydroxide, phenol, sodium hydrogen phosphate dihydrate (daidaituwa tare da abun da ke ciki na Viktoza). Ba kamar Victoza ba, Saxenda yana da ƙananan sakamako masu illa.

Contraindications

Cikakken haramcin amfani da kwayoyi masu dauke da sinadarin liraglutide:

• tafiyar kumburi a cikin narkewa,
• rikicewar kwakwalwa
• cutar hanta, cututtukan hanji,
• ciki, lactation,
• nau'in ciwon sukari guda 1
• barasa ya ci a lokacin jiyya (karfinsu ba a kafa ba),
• mai ciwon sukari ketoacidosis,
• lalacewar aikin na koda, hanta,
• paresis na ciki
• hypersensitivity zuwa abubuwan da ke ciki.

Abubuwan da ke alaƙa da ma'amala don amfani da samfuran samfuran samar da abinci na liraglutide:

• zuciya da cututtukan jijiyoyin jiki,
• bugun zuciya
• shan magunguna masu ɗauke da GLP-1,
• shekaru har zuwa 18 da fiye da 75 years old,
• liyafar hanya don asarar nauyi.

Side effects

Wadanda ke shan miyagun ƙwayoyi na iya haɓaka halayen marasa kyau:

• hawan jini,
• rage cin abinci
• mayuka
• maƙarƙashiya, zawo, belching,
• ciwon kai
• bushewa
• ciki, gajiya, kasala, rage aiki,
• anorexia.

Umarnin don amfani da Liraglutida

Ana gudanar da shirye-shiryen Saksenda da Viktoza ne kawai subcutaneously, sau ɗaya a rana a lokaci guda. Zai fi kyau a zaɓi don yin allura a cinya, ciki ko kafada. Maganin farko zai zama 1.8 MG, akan lokaci ana iya kawo shi zuwa 3 MG. Ba za ku iya shigar da kashi biyu na kwana ɗaya ba. Tsawon lokacin jiyya yana gudana daga watanni 4 zuwa shekara, yana da amfani a yi wasanni a lokaci guda, bi abinci. Tare tare da liraglutide, thiazolidinediones da metformin za'a iya tsara su.

Yadda za a yi amfani da alkairin sirinji

Maganin shine kawai ake gudanar dashi. Ruwa ya kamata ya kasance da yawan zafin jiki a dakin. Matsayi na amfani:

1. Cire hula daga hannun, cire lakabin daga allura, rike shi da hula, saka shi cikin goshin. Juya zare, kulle allura.
2. Cire iska ta cire hula daga allura kuma juya ƙarshen zuwa ƙasa. Shake sirinji don sakin iska, danna maɓallin don digo ya gudana daga ƙarshen allura.
3. Juya maɓallin allura zuwa kashi da ake so akan sikelin ta jujjuya sirinji. Lambar da ke cikin akwatin zai nuna sashi.
4. Kowane lokaci kuna buƙatar yin allura a wani wuri daban. Tsaftace wurin allura tare da goge giya, bushe, riƙe sirinji da hannu ɗaya, kuma ninka tare da ɗayan. Saka allura, saki fati, danna maɓallin a hannun, saki bayan sakan 10.
5. Cire allura daga fata yayin riƙe maɓallin. Matsa wurin allura tare da adiko na goge baki, tabbatar cewa akwai 0 akan taga.
6. Cire allura, saka a hula, jujjuya shi, kwance allurar, watsar da shi. Sauya hula.
7. Adana sirinji a cikin kayan ɗakinta na asali. An hana shi barin allura a jiki ya yi amfani da shi sau biyu.

Analogs na Victoza da Saxends

Sauya magunguna tare da kayan aikin da za'a iya sayansu a kusan farashin:

1. Forsyga - 2500 p., Rage sukari jini.
2. Orsoten - 650 p., Capsules don asarar nauyi, haɓaka metabolism na glucogone.
3. Liksumiya - 6750 p., Rage sukari jini.
4. Ximia - 2000 p., Inganci a cikin kiba.
5. Reduxin - 1400 rubles, yana rage nauyi, yana taimaka wajan ƙona kitse.
6. Diagninide - mai arha ne, 200 rubles, yana taimakawa tare da kiba.
7. Belvik - 13,000 rubles, yana rage yawan ci, ba a sayar da shi a hukumance a Rasha.
8. Baeta - 8000 rubles, peptide na amino acid wanda ke rage jinkirin motsa jiki da rage cin abinci, yana shafar masu karɓa.

Abun ciki, tsari na saki da aikin magani

An samar da miyagun ƙwayoyi a cikin nau'i mai warwarewa mara launi, wanda aka ƙaddara don gudanar da aikin subcutaneous. Babban kayan shine shine Lyraglutide.

Baya ga shi, abubuwan sun hada da:

• prolylene glycol
• hydrochloric acid
• phenol
• sodium hydrogen phosphate,
• ruwa.

Wannan abun da ke ciki shine ana ɗauka mafi dacewa don cika ayyukan da aka sanya wa magani.

A ƙarƙashin tasirin abin da ke ciki, ana inganta aikin samar da insulin ta hanyar ƙwayoyin beta. A sakamakon wannan, tsoka da ƙashin nama na jiki suna cinye glucose kuma suna sake rarraba shi tsakanin sel, wanda ke taimakawa rage yawan sukari a cikin jini. Dangane da wannan, zamu iya cewa wannan magani yana maganin rashin ƙarfi.

Tasirin maganin yana da matukar tasirin gaske, ana nuna shi da tsawan lokaci. Tare da gabatarwar miyagun ƙwayoyi 1 lokaci kowace rana, tasirinsa ya ci gaba na tsawon awanni 24.

Manuniya da contraindications

Kafin amfani da liraglutide, yakamata a karanta umarnin kuma a tabbata cewa wannan kayan aikin ya dace da wani mai haƙuri. Koda likitoci yakamata suyi gwajin farko don gujewa rikice-rikice. Ba a yarda da shan maganin ba.

Ana amfani da magani ga nau'in ciwon sukari na 2. Anyi la'akari da shi a matsayin mai taimako kuma ana amfani dashi a cikin haɗin gwiwa tare da wasu magunguna na ƙungiyar hypoglycemic. Amma wani lokacin Lyraglutide shima yana tasiri a cikin maganin monotherapy.

Bukatar binciken farko na mai haƙuri ya samo asali ne saboda contraindications ɗin da ke cikin ƙwayar.

Daga cikinsu ana kiransu:

• jiki hankali ga kowane daga cikin abubuwan da abun ciki na abun da ke ciki,
• ilimin hanta na hanta
• koda mai aiki,
• gaban mai kumburi tafiyar matakai a cikin narkewa kamar fili,
• nau'in farko na ciwon sukari
• maganin ciwon huhu
• bugun zuciya
• cututtukan tsarin endocrin
• lokacin haihuwa
• lactation.

Baya ga tsauraran matakan contraindications, har yanzu akwai iyakoki:

• cututtuka na tsarin zuciya da jijiyoyin jini,
• shekarun mara lafiya har zuwa shekaru 18,
• tsufa.

A cikin waɗannan halayen, akwai haɗarin rikice-rikice, amma a ƙarƙashin kulawa na ƙwararrun likita ana iya magance shi. Saboda haka, wani lokacin irin waɗannan masu cutar har yanzu ana wajabta su Liraglutid.

Umarnin don amfani

Ana amfani da miyagun ƙwayoyi don allura kawai, wanda ya kamata a gudanar dashi a ƙarƙashin. An hana yin amfani da maganin taurarin ciki ko haramcin amfani da miyagun ƙwayoyi.

Yankunan da suka fi dacewa don yin allura sune bangon ciki na ciki, cinya ko kafada. Yankunan allura suna buƙatar a canza koyaushe don kada lipodystrophy ya faru. Wata doka - gabatarwar miyagun ƙwayoyi ya kamata a aiwatar da su a lokaci guda.

An ƙayyade adadin ƙwayoyi daban-daban. Mafi sau da yawa, jiyya yana farawa da kashi na 0.6 mg. Ana yin allura sau ɗaya a rana. Idan ya cancanta, sashi yana ƙaruwa zuwa 1.2 har ma zuwa 1.8 MG. Yin amfani da liraglutide a cikin adadin da ya wuce 1.8 MG ba wanda ake so ba.

Mafi sau da yawa, ban da wannan magani, ana amfani da samfuran tushen Metformin.

Don hana yanayin hypoglycemic, dole ne a kula da hanyar kulawa. Tabbatar duba sukarin jininka kuma daidaita tsarin kulawa. Don yin kowane canje-canje ba tare da shawarar kwararrun ba a so.

Umarni na bidiyo don subcutaneous management na miyagun ƙwayoyi:

Yin hulɗa tare da wasu magunguna

Liraglutide yana da ikon yin tasiri ga tasiri na wasu kwayoyi. Sabili da haka, ya kamata marassa lafiya su sanar da likitan halartar kowane irin magunguna da aka yi amfani da shi don su iya rubuta ingantaccen magani. Mafi yawan lokuta, sakamako masu illa suna faruwa saboda gaskiyar cewa mai haƙuri yana amfani da magunguna marasa jituwa.

Tsanani da daidaita yanayin zama dole ne dangane da irin wadannan kwayoyi:

• maharan hypoglycemic
• beta hanawa,
• kamuwa da cuta
• ACE masu hanawa
• magungunan anabolic
• maganin hana haihuwa,
• magungunan antimycotic
• salicylates, da sauransu.

Haɗakar hadin gwiwar liraglutide tare da wasu kwayoyi yawanci ana ba da izini, amma galibi ya zama dole a bincika jinin mai haƙuri don abubuwan da ke cikin sukari. A cikin rashin ingantaccen ƙarfin aiki, sashi yana ƙaruwa, tare da bayyanar alamun alamun hypoglycemia, yakamata a rage shi.

Shirye-shirye na irin wannan mataki a allunan

Dalilan da yasa kwararru suka yi amfani da analogues na wannan magani zasu iya bambanta. Ga wasu marasa lafiya, magani bai dace ba saboda contraindications, wasu sun koka da sakamako masu illa, ga wasu, farashin na iya zama kamar ba a yarda da shi ba.

Sauya maganin ta hanyar da ke biye:

1. Rana. Tushenta shine Repaglinide. Suna sakin shi ta hanyar Allunan. Likita ya tsara adadin maganin, dangane da halayen hoton cutar. Ba za ku iya fara ɗaukar Novonorm akan kanku ba, saboda yana da contraindications.
2. Rage abinci. Magungunan yana da tasirin hypoglycemic. Abunda ya ƙunshi abubuwa guda biyu - Metformin da Sibutramine. Ana iya amfani da Reduxine a cikin capsules ko allunan.
3. Diaglinide. An tsara shi don gudanar da maganin baka, mai da hankali kan marasa lafiya da ciwon sukari. Babban sinadaran a cikin kayan sa shine Repaglinide. Kayan aiki yana taimakawa wajen daidaita matakan glucose.
4. Forsyga. Abubuwan da suke aiki da shi shine Dapagliflozin. Abun yana da tasirin hypoglycemic, na iya taimakawa cikin asarar nauyi. Amfani da shi, kuna buƙatar bin umarnin likita.

Mai haƙuri ra'ayi

Daga sake dubawar marasa lafiya da suka dauki Liraglutide, zamu iya yanke shawara cewa kowa ba ya yarda da miyagun ƙwayoyi. Aka ambata suna da ƙarfi sosai sakamako masu illa bayan an ɗauka. Da yawa suna la'akari da sakamakon asarar nauyi asara ce mai kyau.

Ban dade da yin maganin Liraglutide ba. Da farko komai ya yi kyau, har ma kasancewar babu wasu halayen da ba su dace ba. Kuma daga baya binciken ya nuna cewa ina da cututtukan fitsari. Dole ne in ƙi ƙwayoyi.

Farkon magani tare da wannan magani ya kasance mai sauƙi. Na sha wahala daga tashin zuciya, kaina na ji ciwo a kullun, kuma saboda matsalolin matsin lamba yana da wuya a yi aiki har ma in tashi daga gado. Tuni ya nemi neman magani na musanyawa. Ya tsaya cewa matakin sukari yayi daidai kuma ya tabbata. Sannan da alama an yi amfani da gawar, saboda dukkan alamu marasa dadi sun ɓace. Na ci gaba da magani har yanzu. Na lura cewa yana taimakawa rage nauyi, saboda ci yana raguwa. Na rabin shekara Ina da kilogiram 15 kasa da ƙasa, wanda ya ba ni damar jin daɗin kyau - ƙarin nauyin ya ɓace.

Ina amfani da Liraglutid kwanan nan, amma ya dace da ni. Girman sukari ya ragu zuwa matakin al'ada, babu maganganu marasa kyau, kodayake na kasance mai matukar damuwa. Hakanan zan so in rasa nauyi (Na ji cewa ana amfani dashi don wannan), amma har zuwa yanzu asarar nauyi tayi ƙima, kilo 3 kawai.

Ba kowa ba ne zai iya siyan wannan magani, tunda yana ɗayan tsada. Kimanin farashin yana cikin kewayon 7-10 dubu rubles.