Farmasulin HNP

Farmasulin® N NP da Farmasulin® N 30/70 sune shirye-shiryen insulin ɗan adam da aka samu ta amfani da fasaha na DNA. Latterarshe yana da duk halayen halayen insulin. Magunguna na musamman suna sarrafa metabolism a cikin kyallen takarda. Rage sukari na jini. Suna ba da gudummawa ga haɓaka aiki mai aiki da ƙwayoyin carbohydrates da amino acid a cikin sararin samaniya, rage lipolysis, ƙarfafa aikin RNA da sunadarai, kazalika da kunna aikin haɗin glycogen. Magungunan suna haɓaka kwararar potassium a cikin sel daga sararin samaniya, wanda ke taimakawa rage ƙarancin diastolic myocardial depolarization wanda ke faruwa tare da cardiopathy kuma a matsayin sakamako na gefen lokacin amfani da digitalis, GCS da catecholamines.
Farawar sakamako shine 1 sa'a bayan aikin Farmasulin® N NP ko mintuna 30 bayan aikin Farmasulin® H 30/70. Ana lura da mafi girman yawan hankali da warkewa tsakanin sa'o'i 2 zuwa 8 yayin amfani da NPP na Farmasulin® N ko tsakanin 1 da 8.5 lokacin amfani da Farmasulin® H 30/70. Tsawan lokacin kula da warkewa shine 18-20 awanni ko 14-15 sa'o'i, bi da bi.

Alamu don amfani da miyagun ƙwayoyi Farmasulin

Mellitus na insulin-dogara da ciwon sukari mellitus (nau'in I), wanda ba shi da insulin-da ke fama da ciwon sukari mellitus (nau'in II), idan ba zai yiwu a sami diyya na cutar tare da cin abinci da magungunan ƙwayoyin cuta na baka. Kowane irin nau'in ciwon sukari da rikitarwa ta hanyar kamuwa da cuta, cututtukan fata marasa magani, ƙwayar cuta, ƙarancin ƙwayar zuciya tare da ambaliya, ci gaba na retinopathy, ayyukan tiyata a cikin marasa lafiya da ciwon sukari, ketoacidosis masu ciwon sukari, precoma da coma, juriya ga sulfonylureas, lokacin daukar ciki a cikin marasa lafiya. ciwon sukari.

Yin amfani da miyagun ƙwayoyi Farmasulin

P / c. An sanya allurai da lokacin gudanarwa daban daban ga kowane mara lafiya. Ana amfani da miyagun ƙwayoyi 1 ko sau da yawa a rana. Tazara tsakanin allurar SC da abincin abinci ya zama bai wuce minti 45-60 ba (bai wuce minti 30 ba lokacin amfani da Farmasulin® N 30/70). Yin amfani da miyagun ƙwayoyi ya kamata ya kasance tare da wani abincin da ya zama dole. Lokacin ƙayyade adadin kuzari na abinci (a matsayin mai mulkin, adadin kuzari 1700-3000), ya zama dole a jagoranci shi ta hanyar nauyin jikin mai haƙuri, da kuma yanayin ayyukansa. Lokacin ƙayyade kashi na farko na miyagun ƙwayoyi, ya zama dole a bishe shi ta hanyar yawan glycemia na azumi da lokacin rana, kazalika da matakin glucosuria yayin rana. A cikin ƙididdigar yawan adadin magungunan, ana iya jagorar mutum ta hanyar la'akari da masu zuwa: idan matakin glycemia ya wuce 9 mmol / L, 2-4 IU na insulin ana buƙatar don gyaran kowane mai zuwa 0.45-0.9 mmol / L na glucose jini. Zaɓin ƙarshe na kashi na insulin ana aiwatar da shi a ƙarƙashin ikon janar yanayin haƙuri kuma yin la'akari da glucosuria da glycemia, waɗanda aka lura da banbancin amfani da miyagun ƙwayoyi. Yawanci, maganin yau da kullun shine 0.5-1.0 IU / kg nauyin jiki a cikin manya kuma bai kamata ya wuce nauyin jiki na 0.7 IU / kg a cikin yara ba. A cikin marasa lafiya tare da labile na cutar, a lokacin daukar ciki, a cikin yara - canji a cikin kashi na insulin kada ta wuce 2-4 IU ta 1 allura.
Yin allura
Dole ne ku tabbata cewa ana amfani da sirinji, karatun wanda ya dace da ɗaukar hankalin insulin. Ya kamata a yi amfani da sirinji iri ɗaya da alama iri ɗaya. Rashin kulawa yayin amfani da sirinji na iya haifar da sashin insulin mara kyau. Ana yin allurar kamar haka:

1. Kafin tattara insulin daga murfin, ya zama dole a bincika yanayin abubuwan da ke ciki. Game da turwatsewa ko bayyanar launi na allahntaka bayan daidaita abubuwan da ke cikin vial, bai kamata a yi amfani da wannan magani ba. Nan da nan kafin allura, murfin dakatarwa yana jujjuya tsakanin tafin hannayen don ƙwarjinsa ko'ina cikin vial ya zama rigar.
2. Ana tattara insulin daga vial ta hanyar huɗa tare da allurar sirinji mai ƙwanƙyashe abin toshe kwaya da aka rubba tare da barasa ko kuma maganin giya na aidin. Zazzabi na insulin da ke cikin yakamata ya zama zazzabi a dakin.
3. Idan ana amfani da nau'in insulin guda ɗaya kaɗai, to:
   • ana jan iska zuwa cikin sirinji zuwa ƙimar da ta dace da adadin insulin ɗin da ake buƙata, bayan haka iska ta saki cikin murfin,
   • sirinji tare da vial an juye don haka sai an juya vial a juye kuma ana buƙatar tara adadin insulin,
   • an cire allura daga vial. Ana fitar da sirinji daga cikin iska kuma an duba daidaituwa na adadin insulin.
4. Idan nau'ikan insulin guda biyu sun gauraye, to, nan da nan kafin allurar vial tare da dakatarwar insulin (turbid bayani) ana birgima tsakanin tafukan hannu don hargitsin ya zama ɗaukacin girman murfin ya zama daidai. An zana ƙarar iska a cikin sirinji wanda ya dace da adadin da ake buƙata na dakatarwar insulin, kuma an shigar da wannan iska a cikin murfin tare da dakatarwar insulin. Cire allura daga kwalbar. Hakanan, ana jan iska zuwa cikin sirinji don darajar adadin da ake buƙata na maganin insulin mai ma'ana. Shigar da wannan iska cikin kwalban da maganin insulin. An juye masa sirinji tare da vial don haka vial ta juye kuma ana buƙatar kashi da ake buƙata na maganin insulin na gaskiya. Cire iska daga sirinji ka bincika daidai gwargwado na maganin insulin. Ana sake shigar da allura a cikin murfin tare da dakatar da insulin kuma ana tattara maganin da aka tsara. Cire iska daga sirinji ka duba daidai matakin. A koyaushe wajibi ne a buga insulin a jerin da aka nuna. Wannan yana tabbatar da daidaiton haɗuwa na cakulan a cikin sirinji. Nan da nan bayan kammala ayyukan da ke sama, an yi allura.
5. Riƙe fata tsakanin yatsunsu, allura allura a cikin rufin fatar a wani kusurwa kusan 45 ° kuma a saka allurar s / c.
6. An cire allura kuma ana matse wurin allura dan kadan na dan lokaci don hana kwararar insulin.
7. Buƙatar canja wurin allurar.

Side effects na miyagun ƙwayoyi Pharmasulin

Da wuya - lipodystrophy, juriya na insulin, halayen kwanciyar hankali. Tare da tsawaita aikin insulin a wuraren allura, ana iya lura da sassan atrophy ko hauhawar jini mai ƙananan ƙwayoyin mai. Wadannan abubuwan zasu iya hana ci gaba ta hanyar canza allurar kodayaushe. Idan akwai rashin lafiyar gaba ɗaya ga sauran nau'ikan insulin a cikin tarihin mai haƙuri, ana tsara waɗannan magunguna bayan sun sami mummunan gwajin intradermal. Idan akwai rashin lafiyar, dole ne canja wurin mai haƙuri zuwa wani nau'in insulin kuma sanya masa maganin rashin lafiyan rashin lafiyar. Game da gudanar da sinadarin insulin ko kuma abinci mai tsallakewa, kamar yadda kuma tare da matsanancin motsa jiki, zazzagewar jiki ga insulin zai iya bunkasa. Verearfin hypoglycemia mai tsananin gaske zai iya haɓaka tare da amfani da barasa ta hanyar mai haƙuri da ciwon sukari. Idan maida hankali na glucose a cikin jini yana cikin matakan sosai, yanayin ketoacidosis mai ciwon sukari yana faruwa. Irin wannan rikicewar rikice-rikice na iya haɓaka idan mai haƙuri ya sami ƙananan kashi na insulin fiye da buƙata. Ana iya haifar da wannan ta hanyar buƙatar buƙatar insulin a lokacin rashin lafiya, cin zarafin abinci, gudanarwar insulin na yau da kullun ko isasshen kashi na insulin. Ana iya gano ci gaban ketoacidosis ta hanyar nazarin fitsari, wanda a ciki aka gano babban abun ciki na sukari da jikin ketone. A hankali, yawanci a cikin 'yan sa'o'i ko kwanaki, alamu suna fitowa kamar ƙishirwa, karuwar diuresis, rashin ci, gajiya, bushewar fata, zurfi da saurin numfashi. Idan ba a kula da mai haƙuri a cikin wannan yanayin ba, yana yiwuwa mai ciwon sukari ya taso tare da sakamako mai ƙisa.

Umarnin na musamman don amfanin Farmasulin

A kashi na 4 na 4 na IU, sau 1-2 a rana, ana iya amfani da kwayoyi azaman wakili na anabolic don ƙoshin jiki, furunlera, thyrotoxicosis, atony na ciki, matsanancin hepatitis, da kuma farkon siffofin cirrhosis. A cikin ilimin hauka, an wajabta shi don maganin ƙarfafawa gaba ɗaya. Anyi amfani da shi don maganin cutar malaria, a cikin aikin tiyata.

Abun hulɗa na magunguna

Glucagon, diazoxide, abubuwan da aka samo na phenothiazine, maganin thiazide diuretics, corticosteroids, hormones na thyroid, maganin hana haihuwa na hanji yana lalata tasirin insulin. Anara yawan ƙarfin tasirin tasirin tasirin ƙwayar jijiya yana yiwuwa tare da gudanar da sabis na salicylates, guanethidine, MAO inhibitors, oxygentetracycline, da steroids anabolic. Insulin yana ƙaruwa da maganin cutar tarin fuka na PASK. Insulin da strophanthin suna da bambanci a duka ayyukan kwangila da metabolism metabolism, sakamakon wanda ke raunana juna ko ma murkushe tasirin su yana yiwuwa. A cikin jiyya tare da insulin, tsohuwar gudanarwar anaprilin na iya haifar da tsawan hypoglycemia. Har ila yau, barasa yana kara haɗarin cutar hawan jini.

Yawan shaye shaye, magunguna da magani

Yana da cikakken kuma zumunta. Sanadin wuce haddi hypoglycemic sakamako. Nutritionarancin abinci mai gina jiki (rashin wadatar abinci bayan allurar insulin), yawan motsa jiki da barasa suna taimakawa wurin faruwarsa. Musamman ma sau da yawa yana iya faruwa tare da labile na cutar, a cikin tsofaffi marasa lafiya, tare da nakasa aiki na koda. A hankali aka nuna shi ta hanyar zufa, rawar jiki da sauran halayen masu 'yancin kai, asarar saurin asara. Jiyya ta ƙunshi lokacin glucose a cikin lokaci (a matakin farko na hypoglycemia). Don hana hypoglycemia, ana bai wa mai haƙuri shayi mai zaki ko cuban cuban sukari. Idan ya cancanta, a cikin allurar iv na 40% na glucose ana aiwatar dashi a cikin ciki ko ana sarrafa 1 mg na glucagon intramuscularly. Idan mara lafiya bai murmure daga rashin lafiya ba bayan ya daidaita matakan sukari na jini, to ya zama dole a sarrafa mannitol ko kuma wani babban kaso na corticosteroids don hana farji.

Yanayin ajiya na miyagun ƙwayoyi Farmasulin

A cikin duhu a zazzabi na 2-8 ° °. Kada insulin daskararre ko fallasa ga hasken rana! Za a iya ajiye vial insulin da aka yi amfani dashi a zazzabi a daki (har zuwa 25 ° C) na tsawon makonni 6. Game da turwatsewa ko bayyanar launi na allahntaka bayan daidaita abubuwan da ke cikin vial, bai kamata a yi amfani da wannan magani ba.

Suna:

Farmasulin (Farmasulin)

1 ml na Farmasulin N bayani ya ƙunshi:
Insulin jikin dan adam (wanda aka kirkira ta hanyar fasaha ta DNA) - 100 IU,
Ingredientsarin sinadaran.

1 ml na dakatarwar Pharmasulin H NP ya ƙunshi:
Insulin jikin dan adam (wanda aka kirkira ta hanyar fasaha ta DNA) - 100 IU,
Ingredientsarin sinadaran.

1 ml na dakatarwar Farmasulin H 30/70 ya ƙunshi:
Insulin jikin dan adam (wanda aka kirkira ta hanyar fasaha ta DNA) - 100 IU,
Ingredientsarin sinadaran.

Aikin magunguna

Farmasulin magani ne wanda ke haifar da tasirin sakamako. Farmasulin ya ƙunshi insulin, abu ne wanda yake daidaita metabolism. Baya ga daidaita metabolism na glucose, insulin kuma yana shafar yawancin hanyoyin anabolic da anti-catabolic a cikin kyallen. Insulin yana haɓaka aikin glycogen, glycerin, sunadarai da mai mai a cikin ƙwayar tsoka, haka kuma yana ƙara yawan shan amino acid da rage glycogenolysis, ketogenesis, neoglucogenesis, lipolysis da catabolism na sunadarai da amino acid.
Farmasulin N magani ne mai dauke da insulin-sauri. Ya ƙunshi insulin ɗan adam wanda aka samu ta hanyar fasahar DNA. Ana lura da tasirin warkewa 30 mintuna bayan an gudanar da subcutaneous kuma zai ɗauki awanni 5-7. Mafi girman yawan plasma maida hankali ne a cikin awa 1-3 bayan allura.

Lokacin amfani da miyagun ƙwayoyi Farmasulin H NP, ana lura da mafi girman ƙwayar plasma na abu mai aiki bayan sa'o'i 2-8. Tasirin warkewa yana tasowa a cikin mintina 60 bayan gudanarwa kuma yana ɗaukar tsawon awanni 18-24.
Lokacin amfani da miyagun ƙwayoyi Farmasulin N 30/70, tasirin warkewa yana haɓakawa a cikin mintuna 30-60 kuma yana ɗaukar tsawon awanni 14-15, a cikin wasu marasa lafiya har zuwa 24 hours. Observedarancin plasma maida hankali ne akan aiki mai aiki ana lura da sa'o'i 1-8.5 bayan gudanarwa.

Hanyar aikace-aikace

Farmasulin N:
Magungunan an yi shi ne don gudanar da aiki da jijiyoyin jini na ciki. Kari akan haka, za'a iya gudanar da maganin ta hanyar intramuscularly, dukda cewa an fi son aikin subcutaneous da na ciki. Matsayi da jadawalin gudanarwa na miyagun ƙwayoyi Farmasulin N an ƙaddara ta likita, yin la'akari da bukatun kowane haƙuri. Bayan haka, ana bada shawarar yin magani ga kafada, cinya, buttock ko ciki. A wuri guda, ana bada shawarar allura fiye da lokaci 1 a kowane wata. Lokacin yin allura, guji samun mafita a cikin jijiyoyin bugun jini. Kar a shafa wurin allurar.

Maganin allurar a cikin keken motocin an yi nufin amfani dashi da alkalami mai alamar "CE". An ba shi izinin amfani da tsabtataccen bayani, mara launi wanda ba ya ƙunshi barbashi bayyane. Idan ya zama dole don gudanar da shirye-shiryen insulin da yawa, wannan ya kamata a yi ta amfani da allon alkalami daban-daban. Game da hanyar cajin katun, a matsayin mai mulkin, an bayar da bayani a cikin umarnin don alkairin sirinji.

Tare da gabatarwar mafita a cikin vials, ya kamata a yi amfani da sirinji, karatun wanda ya dace da wannan nau'in insulin. An ba da shawarar cewa a yi amfani da sirinji na kamfani guda da nau'in don gudanar da maganin Pharmasulin N, tun da yin amfani da sauran sirinji na iya haifar da allurar da ba ta dace ba. Kawai bayyananne, launi mara launi wanda baya dauke da abubuwan da ake bayyane an yarda. Ya kamata a aiwatar da allurar ne a ƙarƙashin yanayin da za'a iya amfani da shi. Ana bada shawarar maganin zafin jiki na dakin. Don zana mafita a cikin sirinji, da farko dole ne a jawo iska a cikin sirinji zuwa alamar da ta dace da adadin insulin ɗin da ake buƙata, saka allura a cikin murfin kuma ya zub da iska. Bayan haka, kwalban an juya shi sama kuma ana buƙatar adadin maganin da ake buƙata. Idan ya zama dole don gudanar da insulins daban-daban, ana amfani da keɓaɓɓen sirinji da allura ga kowane.

Farmasulin H NP da Farmasulin H 30/70:
Farmasulin N 30/70 - cakuda-hade cakuda mafita Farmasulin N da Farmasulin H NP, wanda ke ba ku damar shiga cikin insulins iri-iri ba tare da neman kai-tsaye na gaurayar insulin ba.

Farmasulin H NP da Farmasulin H 30/70 ana gudanar da su a ƙarƙashin ƙasa bin ƙa'idodin aseptic. Anyi allurar subcutaneous a cikin kafada, gindi, cinya ko ciki, kodayake, ya kamata a ɗauka a cikin zuciya cewa a wurin yin allurar iri ɗaya yakamata a yi fiye da sau 1 a kowane wata. Guji tuntuɓar da mafita yayin allura. An ba shi izinin amfani da mafita kawai wanda bayan girgiza babu tarar ko tangarda a jikin bangon vial. Kafin gudanarwa, girgiza kwalban a cikin tafin hannunka har sai an samar da abubuwan daidaitawa. An hana shi girgiza kwalban, saboda wannan na iya haifar da haifar da kumfa da matsaloli tare da saita ainihin adadin. Yi amfani da sirinji kawai tare da karatun da ya dace da kashi na insulin. Tsaka-tsakin tsakanin sarrafa maganin da shan abincin ya kamata bai zama bai wuce minti 45-60 na maganin Farmasulin H NP ba kuma bai wuce minti 30 na maganin Far 30ulin ba.

Yayin amfani da magungunan Farmasulin, yakamata a bi tsarin abincin.
Don sanin kashi, yakamata a ɗauki matakin glycemia da glucosuria yayin rana da matakin yin glycemia na azumi.
Don saita dakatarwa a cikin sirinji, dole ne ka fara jan iska a cikin sirinji zuwa alamar da ta ƙayyade adadin da ake buƙata, sannan saka allura a cikin murfin kuma ya zub da iska. Na gaba, juya kwalban a gefe kuma tattara adadin dakatarwar da ake buƙata.

Ya kamata a gudanar da magunguna ta hanyar riƙe fata a cikin babban tsakanin yatsunsu kuma saka allura a wani kusurwa na digiri 45. Don hana yaduwar insulin bayan gudanarwar dakatarwar, ya kamata a matsi da injin ɗin dan kadan. Haramun ne a shafa wurin allurar insulin.
Duk wani sauyawa, gami da nau'in fito da kaya, iri da nau'in insulin, na buƙatar kulawa da likita.

Side effects

A lokacin maganin tare da Pharmasulin, mafi yawan tasirin da ba a ke so shi ne hypoglycemia, wanda zai haifar da asarar hankali da mutuwa. Mafi sau da yawa, hypoglycemia shine sakamakon tsallake abinci, gudanar da babban adadin insulin ko matsanancin damuwa, gami da shan giya. Don kauce wa ci gaban hypoglycemia, abincin da aka ba da shawarar ya kamata a bi kuma ya kamata a gudanar da miyagun ƙwayoyi bisa ga shawarar likita.

Bugu da kari, galibi tare da tsawaita amfani da miyagun ƙwayoyi Farmasulin, haɓakar insulin juriya da atrophy ko hauhawar ƙwayar kitsen subcutaneous a wurin allura mai yiwuwa ne. Hakanan yana yiwuwa haɓakar halayen rashin damuwa, ciki har da waɗanda ke da ƙima a cikin jijiyoyin jijiyoyin jini, bronchospasm, gumi mai yawa da urticaria.
Tare da haɓaka tasirin da ba'a so ba, ya kamata ka nemi likita, kamar yadda wasu daga cikinsu na iya buƙatar katse ƙwayoyi da magani na musamman.

Contraindications

Ba a wajabta Farmasulin ba ga marasa lafiya tare da sananniyar rashin hankali ga abubuwan da ke cikin miyagun ƙwayoyi.
An haramta Farmasulin don amfani da hypoglycemia.
Marasa lafiya da ke fama da ciwon sukari na dogon lokaci, neuropathy masu ciwon sukari, da kuma marasa lafiya da ke karɓar beta-blockers, ya kamata su yi amfani da Pharmulin na miyagun ƙwayoyi tare da taka tsantsan, tunda a irin waɗannan yanayin alamun hypoglycemia na iya zama mai laushi ko canzawa.

Yakamata ku nemi shawara tare da likitan ku game da yawan maganin idan akwai wani ci gaban adrenal, koda, pituitary da thyro gland dysfunctions, da kuma a cikin manyan siffofin cututtuka, kamar yadda a wannan yanayin, ana iya buƙatar daidaita sashin insulin.
A cikin ilimin yara, don dalilai na kiwon lafiya, an ba shi izinin yin amfani da miyagun ƙwayoyi Pharmasulin daga lokacin haihuwa.
Yakamata a yi taka tsantsan lokacin tuki da ƙarancin hanyoyin da ba shi da haɗari da tuki a lokacin da suke tare da Farmasulin.

Ciki

Ana iya amfani da Farmasulin a cikin mata masu juna biyu, duk da haka, ya kamata a ɗauka a cikin zuciya cewa a lokacin daukar ciki, ya kamata a saka kulawa ta musamman ga zaɓin kashi na insulin, tunda a wannan lokacin buƙatar insulin na iya bambanta. An ba da shawarar ku nemi likitan ku idan kun kasance masu juna biyu ko kuma suna shirin yin juna biyu. Ya kamata a sa ido cikin glucose na jini a lokacin daukar ciki.

Hulɗa da ƙwayoyi

Za a iya rage tasirin magungunan Farmasulin yayin da aka hada su da maganin hana haihuwa, magungunan thyroid, glucocorticosteroids, beta2-adrenergic agonists, heparin, shirye-shiryen lithium, diuretics, hydantoin, da magungunan antiepilepti.

Akwai raguwa a cikin buƙatun insulin tare da haɗuwa da magungunan Pharmaulin tare da wakilan maganin antidiabetic, salicylates, monoamine oxidase inhibitors, inhibitors na sulfonamide, masu hana enzyme mai hanawa, abubuwan talla na beta-adrenergic, masu amfani da giya, almara kuma phenylbutazone.

Yin hulɗa tare da wasu kwayoyi da sauran nau'ikan ma'amala

Wasu kwayoyi suna shafar metabolism metabolism. Yakamata a sanar da likita game da duk wani magani mai gamsarwa da aka bayar yayin hadewa da amfani da insulin mutum.

Idan kana buƙatar amfani da wasu magunguna, ya kamata ka nemi likitanka.

Bukatar insulin na iya ƙaruwa tare da amfani da kwayoyi tare da aikin hyperglycemic, kamar su hana hana haihuwa, glucocorticoids, hormones thyroid da hormone girma, danazole, β ₂ jinƙai mai mahimmanci (misali, ritodrin, salbutamol, terbutaline), thiazides.

Bukatar insulin na iya raguwa tare da yin amfani da kwayoyi tare da aikin hypoglycemic, kamar magungunan maganganu na baki, salicylates (alal misali acetylsalicylic acid), sulfaantibiotics, wasu maganin antidepressants (MAO inhibitors), wasu angiotensin-inhibiting enzyme inhibitors (blockptenaprilprorilll, Captapri marasa β-blockers ko barasa.

Somatostatin analogues (octreotide, lanreotide) na iya haɓakawa da raunana buƙatar insulin.

Siffofin aikace-aikace

Duk wani musanyar nau'in ko nau'in insulin dole ne a yi shi a ƙarƙashin kulawar likita. Canji a cikin maida hankali, alama (masana'anta), nau'in (mai sauri, matsakaici, aiki mai tsawo), nau'in (insulin dabba, insulin mutum, analog na insulin mutum) da / ko hanyar shirya (insulin da aka samu ta amfani da fasahar DNA. sabanin insulin dabba) na iya buƙatar canjin sashi.

Sashi a cikin lura da marasa lafiya da insulin na mutum zai iya bambanta da sigar da ake amfani da shi wajen maganin insulin asalin dabbobi. Idan akwai buƙatar daidaitawar kashi, ana iya aiwatar da irin wannan gyaran daga kashi na farko ko a cikin weeksan makonnin ko watanni na farko.

A cikin wasu marasa lafiya waɗanda ke da alamun halayen hypoglycemic bayan canja su daga tsari na kula da insulin na asalin dabbobi zuwa tsarin kulawa da insulin na mutum, alamun farko na hypoglycemia sun kasance ba a faɗi ko bambanta da alamu waɗanda aka lura da su a cikin waɗannan marasa lafiya lokacin da aka bi da su da insulin dabbobi. A cikin marasa lafiya tare da babban ci gaba a cikin matakan glucose na jini (alal misali, saboda ƙaruwar ƙwayar insulin), wasu ko babu alamun farkon faɗakarwar cutar rashin ƙarfi a cikin nan gaba, wanda ya kamata a sanar dasu game da. Alamar farkon cutar sanyin hypoglycemia na iya zama dabam ko kuma karancin sanarwa a cikin marassa lafiya da ke da nau'in ciwon suga da masu ciwon suga, ko kuma a cikin marasa lafiya da ke shan wasu magunguna, kamar su β-blockers, a layi daya tare da maganin da ake amfani da shi.

Hypoglycemia ko hyperglycemic halayen da ba a gyara ba na iya haifar da asarar sani, ko na ciki, ko mutuwa.

Singarancin allurar ko dakatarwa na magani (musamman ga marasa lafiya da ke fama da ciwon sukari da ke fama da cutar suga) na iya haifar da cutar sikari da cutar ketoacidosis mai saurin kamuwa da ita.

Ana iya samar da rigakafin ƙwayoyin cuta a cikin aikin insulin na mutum, amma a mafi ƙarancin maida hankali sama da insulin dabbobi masu tsabta.

Bukatar insulin ya canza sosai tare da aiki mai rauni, ƙwayar ciki, glandar thyroid, koda ko gazawar hanta.

Hakanan buƙatar insulin na iya ƙaruwa yayin rashin lafiya ko a ƙarƙashin rinjayar damuwa na damuwa.

Bukatar daidaitawa na iya faruwa idan akwai canje-canje a cikin yawan motsa jiki ko abinci na yau da kullun.

Hada amfani da pioglitazone

An ba da rahoton maganganun cututtukan zuciya tare da yin amfani da pioglitazone tare da insulin, musamman a cikin marasa lafiya waɗanda ke da haɗarin haɗari ga rashin zuciya.

Yi amfani da lokacin daukar ciki ko lactation.

Kula da isasshen matakin glucose na jini a cikin mata masu juna biyu na da matukar mahimmanci idan aka kula dasu da insulin (tare da cututtukan da suka shafi ciki). Bukatar insulin yawanci yana raguwa yayin farkon watanni na ciki, bayan haka yana ƙaruwa yayin watanni na biyu da na uku. Matan da ke da ciwon sukari ya kamata su sanar da likitocinsu game da juna biyu ko kuma niyyarsu ta yi juna biyu.

Monitoringuntataccen saka idanu na glucose na jini da lafiyar gaba ɗaya yana da mahimmanci ga mata masu juna biyu masu ciwon sukari.

A cikin mata masu fama da ciwon sukari, yayin shayarwa, ana iya buƙatar buƙatar daidaita alluran insulin da / ko abinci.

Thearfin yin tasiri akan ƙimar amsawa yayin tuki motocin ko wasu hanyoyin.

Hypoglycemia na iya yin mummunan tasiri game da maida hankali da ratsa jiki, wato, haɗari ne cikin yanayin da ke buƙatar halayen da aka ambata, alal misali, lokacin tuki mota ko kuma kera injuna.

Ya kamata a sanar da mara lafiya game da ainihin abin da ya kamata a ɗauka kafin yin tuƙi don guje wa rikicewar cututtukan hypoglycemia, musamman idan alamun gargaɗin farkon rashin ƙarfi na hypoglycemia ba su ɓoye ko ba a bayyane ba, ko kuma yawan maganganun cututtukan cututtukan jini suna faruwa akai-akai. A irin waɗannan halayen, kar ku tuƙi.

M halayen

Hypoglycemia sakamako ne na kowa sakamako na insulin farji a cikin marasa lafiya da ciwon sukari. Mai tsananin rashin ƙarfi na iya haifar da asarar hankali, a wasu yanayi masu ƙima - ga mutuwa. Ba a ba da bayanai game da yawan cututtukan hypoglycemia ba, tunda hypoglycemia yana da alaƙa da kashi na insulin kuma tare da wasu abubuwan, kamar abincin mai haƙuri da matakin aikin jiki.

Ana iya bayyanar da bayyanar cututtuka na gida game da canje-canje a wurin allurar, jan fata, kumburi, itching. Yawancin lokaci suna wucewa zuwa 'yan kwanaki zuwa makonni da yawa. A wasu halaye, ana danganta shi ba tare da insulin ba, amma tare da wasu dalilai, alal misali, haushi a cikin abubuwan da ke tattare da tsabtace fata ko rashin kwarewa da injections.

Cutar rashin lafiyan tsoka babbar illa ce illa ga mutum yana kuma haifar da yanayin rashin lafiyan mutum ga insulin, gami da fitsari a duk fuskar jiki, karancin numfashi, hancin jiki, raguwar hauhawar jini, hauhawar zuciya, da kuma kara karfin jiki. Mummunan shari'ar ƙwayoyin cuta masu haɗari suna barazanar rayuwa. A wasu halaye na musamman na mummunan rashin lafiyan zuwa Farmasulin ® N NP, ya kamata a dauki matakan da suka dace nan da nan. Yana iya zama mahimmanci don maye gurbin insulin ko desensitizing far.

Lokaci-lokaci, lipodystrophy na iya faruwa a wurin allurar.

An ba da rahoton maganganun cututtukan edema tare da yin amfani da ilimin insulin, musamman a lokuta tare da rage yawan metabolism a baya, an inganta shi ta hanyar maganin insulin mai zurfi.

Abun ciki da nau'i na saki

Abun ciki da nau'i na saki

FARMASULIN® H NP

dakatarwa. d / in. 100 IU / ml fl. 10 ml, No. 1
dakatarwa. d / in. Katin 100 IU / ml 3 ml, A'a 5

Insulin mutum 100 IU / ml
Sauran kayan abinci: dist-m-cresol, glycerol, phenol, sulfate protamine, zinc oxide, sodium phosphate dibasic, hydrochloric acid 10% bayani ko sodium hydroxide 10% bayani (har zuwa pH 6.9-7.5), ruwa don allura.
1 ml na Farmasulin N NP ya ƙunshi IU 100 na insulin biosynthetic ɗan adam wanda aka yi ta amfani da fasaha na sake amfani da DNA.

FARMASULIN® H 30/70

dakatarwa. d / in. 100 IU / ml fl. 10 ml, No. 1
dakatarwa. d / in. Katin 100 IU / ml 3 ml, A'a 5

Insulin mutum 100 IU / ml
Sauran abubuwan da ke ciki: dist-m-cresol, glycerol, phenol, sulfate protamine, zinc oxide, sodium phosphate dibasic, hydrochloric acid 10% bayani ko sodium hydroxide 10% bayani (har zuwa pH 6.9-7.5), ruwa don allura.
1 ml na Farmasulin H 30/70 ya ƙunshi 100 IU na insulin biosynthetic ɗan adam wanda aka yi ta amfani da fasaha na sake amfani da DNA.

Pharmacokinetics

Farmasulin N - insulin mai aiki da sauri, shiri ne na insulin ɗan adam wanda aka samu ta hanyar fasahar DNA.
Pharmakokinetics na insulin baya nuna aikin metabolism na aikin.
Farawar tasirin shine mintina 30 bayan gudanarwar subcutaneous. Ana lura da mafi girman yawan hankali tsakanin awa 1 zuwa 3 bayan allura. Tsawan lokacin kula da warkewa daga 5 zuwa 7 ne. Ayyukan insulin ya bambanta da girman adadin sa, wurin allurar, zazzabi na yanayi da aikin mai haƙuri.
Yayin nazarin toxicological, ba a gano wani mummunan sakamako da ya shafi amfani da miyagun ƙwayoyi ba.