Atoris Allunan analogues

Yin amfani da Atoris (ko analogues), ana iya samun kyakkyawan sakamako a cikin maganin cututtukan cututtukan zuciya da cututtukan zuciya. Ana amfani da wani magani da ƙwazo don hana waɗannan yanayin a cikin mutane fiye da 55 shekara. Atoris yana da fa'ida sosai, saboda haka kuna buƙatar la'akari da sifofin amfanin ta, da kuma ƙayyadaddun wurare masu tsadarta. Wadannan sun hada da kwayoyi kamar Lipoford, Atomax, da Atorvastatin. Abubuwan da aka lissafa analogues na miyagun ƙwayoyi da Atoris kanta suna da abun da ke cikin jikin su abu ne na yau da kullun - alli na atorvastatin.

A taƙaice bayanin Atoris

Akwai allunan Atoris a cikin fakitoci suna da sashi na 10, 20, 30, 40, 60 ko 80 mg. Wannan magani ne na statin wanda yake aiki cikin wani yanayi. Alum din atorvastatin yana taimakawa rage ayyukan enzyme, wanda shine yake tabbatar da canzawar HMG-CoA zuwa mevalonic acid. Arfafa wannan canjin yana ɗaukar barbashi na mummunan cholesterol, cire su daga tasoshin. Wannan yana rage taro LDL cholesterol a cikin jini.

Allunan Atoris suna da tasirin anti-atherosclerotic, wanda ke bayyana kanta ta hanyar aiwatar da babban abu akan tasoshin jini da abubuwanda ke cikin jini.

Tabbatacciyar tasirin atorvastatin a saman tasoshin jini an tabbatar dashi ta hanyar dakatar da kwayar halittar isoprenoids, wanda hakan zai rage yiwuwar yaduwar hancinsu na ciki, wanda ke nufin raguwa a cikin gibin su.

Daga cikin shawarwarin gaba daya na shan maganin, ana iya rarrabe masu zuwa:

1. Yarda da kai tsaye ga abinci (kafin da lokacin jiyya) zai taimaka wajen rage yawan lipids na jini.
2. Ya kamata a sha miyagun ƙwayoyi a lokaci guda 1 lokaci ɗaya kowace rana.
3. Wajibi ne a kula da alamun alamun aikin hanta.
4. Tare da haɓakar ciwon tsoka ko rauni na yanayin da ba a sani ba, tare da zazzabi, ana bada shawara a daina shan Atoris kuma a nemi likita.
5. Atoris yana contraindicated a cikin ƙananan, kamar yadda mata yayin lokacin lactation da ciki.
6. Daga cikin contraindications akwai gazawar hanta, cirrhosis, cutar tsoka.
7. Idan akwai wani rashin lafiyar to ɗaya daga cikin abubuwan da ke tattare da miyagun ƙwayoyi, to ba'a ba da shawarar gudanarwarsa ba.
8. Tare da matsanancin hankali ya kamata a ɗauka a cikin marasa lafiya da ke fama da buguwa.

Bayan makonni biyu na magani, ƙwayar jini zata faɗi. Wannan zai bayyana a cikin binciken. Ana iya jin sakamako mafi ƙaranci bayan kwanaki 25-30. Sakamakon warkewa daga magani zai kasance mafi dawwama kawai lokacin kammala dukkan karatun da likita yayi. A wannan yanayin, za a tantance matakin ta hanyar matakin farko na LDL cholesterol a cikin jini da tsananin cutar.

Siffofin amfani da miyagun ƙwayoyi-analog Lipoford

Lipoford asalin asalin Indiya ne kuma ɗan isharar mai rahusa ce ta Atoris. Ana samun magungunan a cikin nau'ikan allunan tare da maida hankali kan sashi mai aiki na 10 ko 20 MG. Lipoford wani yanki ne na magunguna masu rage kiba wadanda ake amfani da su wajen yin rigakafi da kuma kula da cututtukan zuciya wanda babban sanadarin ya haifar.

Specificayyadaddun aikin Lipoford da Atoris kusan iri ɗaya ne, tunda duka sun haɗa da alli atorvastatin a matsayin babban sinadari mai aiki. Amma don maye gurbin Atoris tare da rahusa mai rahusa, yana da mahimmanci a nemi shawara tare da likitan da ya tsara maganin.

Nunin amfani da Lipoford na iya zama ɗayan sharuɗɗan:

• concentara yawan taro yawan ƙwayoyin cuta,
• ƙara yawan ƙwayoyin LDL
• matakan hawan jini na apolipoprotein B da triglycerides,
• primary, heterozygous familial da rashin familial hypercholesterolemia (idan LDL cholesterol yayi yawa),
• Iyalin hypercholesterolemia,
• Cakuda maganin cuta,
• babban taro na triglyceride,
• dysbetalipoproteinemia,
• ilimin halittar jini na zuciya da jijiyoyin jini tsarin,
• hadarin kamuwa da cutar cututtukan zuciya: tsufa, abubuwan nicotine, ciwon sukari, da sauransu.

Lokacin amfani da Lipoford, kuna buƙatar bin abinci na musamman. Abincin abinci mai gina jiki ya kamata ya danganta da ƙananan jita-jita na abinci da abinci.

Atomax shine asalin Atoris na asali

Atomax wani ɗan Atoris ne na Indiya wanda ya ƙware da farashi mai araha. Tsarin saki daya ne. Allunan ana samun su ne a allurai biyu kawai: 10 da 20 mg. Babban abin da ke jikin Atomax shine atorvastatin calcium trihydrate. Haɗin ya haɗa da ƙarin ƙarin abubuwa 10, ciki har da lactose, crospovidone, sitaci, da sauransu.

Ana daukar Atomax da baka, ba tare da cin abincin ba. Magungunan suna da kyau sosai, kuma bayan 1-2 sa'o'i 1-2 ana lura da mafi yawan abubuwan aiki a cikin jini.

Contraindications don shan Atomax na iya zama:

• alerji da aka gyara a cikin abun da ke ciki na samfurin,
• ciki a kowane lokaci
• nono
• haɓakar cutar hanta,
• karuwa da aiki transaminase aiki,
• shekarun yara
• barasa
• duk wata cutar hanta (amfani da samfurin tare da taka tsantsan kuma koyaushe ƙarƙashin kulawar likita),
• damuwa damuwa ma'aunin lantarki,
• rikice-rikice a cikin tsarin endocrine,
• haɓaka yanayin cutar (misali, tsintsaye),
• ayyukan tiyata, da sauransu.

Babban abin da mai haƙuri ya kamata ya tuna: Ana iya amfani da Atomax tare da cholesterol, amma kamar yadda likita ya umarta. Wannan saboda gaskiyar cewa tare da rashin ingantattun magunguna, da yiwuwar samun nau'ikan tasirin sakamako masu illa suna ƙaruwa sau da yawa.

Madadin cikin gida Atorvastatin

Daga cikin magungunan cikin gida waɗanda zasu iya maye gurbin Atoris, an sanya magani wanda yake da suna tare da babban abu mai aiki - Atorvastatin. Kudinsa ya wuce duk analogues na Atoris, kamar yadda aka samar dashi a cikin Tarayyar Rasha kuma ba kasashen waje ba. Amma dangane da tasiri, magungunan ba su da kyau. Allunan ana yin su tare da karfi daban-daban na abu mai aiki: 10-40 MG.

Ana iya tsara wannan asalin don alamomin iri ɗaya kamar magungunan da ke sama, tunda abubuwan haɗin su kusan iri ɗaya ne. Daga cikin manyan abubuwanda suka hada da juna biyu shine daukar ciki, shayar da mama, cutar hanta a cikin mummunan hali, da kuma rashin jindadin juna.

Daga cikin sakamako masu illa na iya bayyana:

• tashin hankali na bacci
• ciwon kai
• take hakkin sitadi (zawo, maƙarƙashiya),
• tashin zuciya
• kara gas a cikin hanjin,
• general malaise
• ciwon baya
• katsewa
• fata fitsari, da sauransu.

Idan ana tasirin cholesterol, kayan aikin zai taimaka wajen magance matsalar, amma ya dace da maganin da ya dace. Saboda haka yana da matukar muhimmanci a bi tsarin kulawa da likitan ya tsara. Game da yawan abin sama da ya kamata, an dakatar da maganin. Ana iya hana sha na gaba ta hanyar wanke ciki, shan mayuka ko wasu abubuwan sha. Bugu da ƙari, likita na iya ba da maganin cututtukan alamomi, wanda za a yi ƙoƙarin sa ido da kuma riƙe mahimman ayyuka.

Mafi arha na Abubuwan Atoris

Analog mai rahusa daga 250 rubles.

An yi wannan musanyar a cikin Rasha, saboda haka farashi da ƙasa da "maganin asali". Ya ƙunshi jerin lambobi iri ɗaya don alƙawarin. Contraindicated idan akwai wani tashin hankali ga miyagun ƙwayoyi, cutar hanta, a lokacin daukar ciki da lactation.

Analog mai rahusa daga 211 rubles.

Mai samarwa: Oxford (India)
Siffofin Saki:

• Allunan kwayoyi 20 MG, 30 inji mai kwakwalwa.

Wani magani dangane da atorvastatin alli a cikin kwamfutar hannu. Haɗin Lipoford ba shi da bambanci sosai da Atoris, don haka alamun, contraindications da tasirin sakamako kusan iri ɗaya ne.

Atomax (Allunan) itute madadin Rating: 127 Top

Analog mai rahusa daga 179 rubles.

Mai samarwa: Hetero Drags Limited (India)
Siffofin Saki:

• Allunan kwayoyi 20 MG, 30 inji mai kwakwalwa.

Atomax shine madadin Indiya don Atoris yana da wannan nau'in sakin. Haka nan ana amfani da magunguna masu rage ƙarfi da amfani da DV. Contraindicated lokacin daukar ciki da lactation. Abunda zai yiwu, yin shawarwari tare da likita ya zama tilas.

Analogs a cikin kayan haɗin da nuni don amfani

Jerin da aka bayar na magungunan analogues na miyagun ƙwayoyi, wanda ke nuna Atoris maye gurbinsu, ya fi dacewa saboda suna da tsari iri ɗaya na abubuwa masu aiki da daidaituwa bisa ga nuni don amfani

Analogs ta hanyar nuni da hanyar amfani

Abun daban-daban, na iya daidaituwa cikin nuni da hanyar aikace-aikace

Yaya za a sami analog mai rahusa na magani mai tsada?

Don neman analog mai rahusawa ga magani, jana'iza ko alaƙa, da farko muna bada shawara a kula da abun da ke ciki, wato ga abubuwa masu aiki iri ɗaya da alamomi don amfani. Abubuwa masu aiki iri ɗaya na ƙwayoyi zasu nuna cewa maganin yana da alaƙa tare da miyagun ƙwayoyi, daidai da magunguna ko madadin magunguna. Koyaya, kar ka manta game da abubuwanda suka lalace na irin kwayoyi, wanda zai iya shafar aminci da tasiri. Kada ku manta game da umarnin likitoci, magani na kai na iya cutar da lafiyar ku, don haka koyaushe tuntuɓi likitanku kafin amfani da kowane magani.

Aikin magunguna

Atorvastatin wakili ne na jini daga rukunin mutum-mutumi. Babban aikin aiwatar da atorvastatin shine hana ayyukan HMG-CoA reductase, enzyme wanda ke daukar nauyin juyar da HMG-CoA zuwa mevalonic acid. Wannan canjin yana ɗayan matakan farko a cikin ƙwayar cholesterol (cholesterol) sarkar sarkar a cikin jiki. Atorvastatin hanawa da kwayar cholesterol yana haifar da karuwa da masu karɓar LDL a cikin hanta, da kuma a cikin ƙwayoyin cuta na extrahepatic. Waɗannan masu karɓa suna ɗaukar barbashi na LDL kuma suna cire su daga plasma jini, wanda ke haifar da raguwa a cikin taro na LDL-C a cikin jini.

Sakamakon antiatherosclerotic na atorvastatin sakamako ne sakamakon tasirinsa akan bangon jijiyoyin jini da abubuwan haɗin jini. Atorvastatin yana hana ayyukan haɗin gwiwar isoprenoids, waɗanda sune abubuwan haɓaka abubuwan haɓaka ƙwayoyin sel na ciki na jijiyoyin jini. A ƙarƙashin tasirin atorvastatin, haɓaka aikin endothelium wanda ke dogara da tasoshin jini yana inganta, taro na cholesterol-LDL, apolipoprotein B, triglycerides (TG) ya ragu, maida hankali kan cholesterol-HDL da apolipoprotein A yana ƙaruwa.

Atorvastatin yana rage dankowar jinin jini da aikin wasu abubuwan hadewar jini da hadewar platelet. Saboda wannan, yana haɓaka hemodynamics kuma yana daidaita yanayin tsarin coagulation. HMG-CoA reductase inhibitors suma suna shafar metabolism na macrophages, toshe tasirinsu da hana katsewa daga cikin matsanancin yanayin atherosclerotic.

A matsayinka na mai mulkin, tasirin warkewa na atorvastatin yana tasowa bayan makonni 2 na amfani da Atoris®, kuma ana samun sakamako mafi girma bayan makonni 4.

Mahimmanci yana rage haɗarin ci gaba da rikitarwa na cutar ischemic (gami da mutuwa daga infarction na zuciya) ta hanyar kasha 16%, haɗarin sake komawa asibiti don angina pectoris, tare da alamun ischemia na myocardial, da kashi 26%.

• Rage yawan adadin cholesterol, cholesterol-LDL, apolipoprotein B da triglycerides a cikin jini na marasa lafiya tare da babban hyperlipidemia (nau'ikan Fredrickson IIa da IIb), ciki har da polygenic hypercholesterolemia, familial heterozygous hypercholesterolemia da hyperliplestidemia.
• Ragewa a cikin karuwar yawan adadin cholesterol, cholesterol-LDL da apolipoprotein B a cikin marasa lafiya tare da hyzycholesterolemia na homozygous.
• Atoris® yana ƙara yawan haɗuwa da HDL-C a cikin ƙwayar jini kuma yana rage raunin LDL-C / HDL-C.
• Ana amfani dashi idan akwai ƙarancin tasirin magani da sauran hanyoyin rashin magani.

Rigakafin Cutar zuciya:

• Babban rigakafin rikice-rikice na jijiyoyin jini a cikin marasa lafiya ba tare da alamun asibiti na cututtukan zuciya ba, amma tare da dalilai masu haɗari don ci gabanta: shekarun da suka wuce shekaru 55, nicotine jaraba, hauhawar jijiyoyin jini, mellitus ciwon sukari, ƙananan matakan HDL-C a cikin jini, ƙaddarar jini, gami da a kan asalin cutar dyslipidemia.
• Tallafin sakandare na rikicewar cututtukan zuciya a cikin marasa lafiya da cututtukan zuciya na zuciya don rage jimlar yawan mace-mace, bugun zuciya, bugun jini, sake komawa asibiti don angina pectoris da buƙatar farfadowa.

Contraindications

• Rashin hankali ga kowane ɓangaren magungunan.
• Cututtukan hanta masu aiki (gami da cutar hepatitis, hepatitis na kullum).
• Rashin hanta.
• Cirrhosis na hanta na kowane etiology.
• Anara yawan ayyukan hematic transaminases na asalin da ba a san shi ba fiye da sau 3 idan aka kwatanta da VGN.
• Cutar tsoka mai rauni.
• Rashin ƙwayar Lactase, rashin haƙuri a cikin lactose, cutar glucose-galactose malabsorption syndrome.
• Ciki da lokacin shayarwa.
• Shekaru har zuwa shekaru 18 (ba a kafa ingantaccen aiki da amincin amfani ba).

Tare da taka tsantsan: shan giya, tarihin cutar hanta.

Haihuwa da lactation

Atoris® yana contraindicated a cikin ciki da lokacin shayarwa. Nazarin dabbobi sun nuna cewa hadarin ga tayin na iya wuce duk wata fa'ida ga mahaifiyar.

A cikin mata masu haihuwa, waɗanda ba sa amfani da hanyoyin ingantaccen maganin hana haihuwa, ba da shawarar amfani da Atoris®. Lokacin da kake shirin yin juna biyu, dole ne ka daina amfani da Atoris® aƙalla wata 1 kafin yin cikin da kake shirin ciki.

Babu wani tabbaci game da rarraba atorvastatin tare da madara. Koyaya, a cikin wasu nau'in dabbobi, haɗuwa da atorvastatin a cikin jini da madara nono daidai yake. Idan ya zama dole a yi amfani da maganin Atoris® a lokacin shayarwa, don guje wa hadarin da ke faruwa a cikin jarirai, ya kamata a daina shayarwa.

Umarni na musamman

Kafin fara jinya tare da Atoris®, dole ne a tsara mai haƙuri da daidaitaccen tsarin abinci mai gina jiki, wanda dole ne ya bi yayin duk lokacin kulawa.

Ana iya lura da haɓaka ayyukan enzymes na hepatic a cikin jijiyoyin jini yayin kulawa tare da Atoris®. Wannan ƙaruwa yawanci ƙarami ne kuma bashi da mahimmancin asibiti. Koyaya, ana bada shawara don saka idanu akan ayyukan ayyukan enzymes na hanta a cikin ƙwayar jini kafin jiyya, bayan makonni 6 da 12 kuma tare da haɓaka kashi na atorvastatin. Idan akwai ƙaruwa sau uku a cikin ayyukan ACT da / ko alT dangi da HBV, ya kamata a dakatar da jiyya tare da Atoris®.

Atorvastatin na iya haifar da karuwa a cikin ayyukan CPK da aminotransferases.

A cikin mata masu haihuwa da ba sa amfani da abin da aka hana, amma ba a shawarar amfani da Atoris®. Idan mara lafiyar yana shirin daukar ciki, to ya kamata ta daina shan Atoris® aƙalla wata ɗaya kafin shirin yin ciki.

Yakamata a gargadi marassa lafiya cewa yakamata su nemi likita kai tsaye idan zafin da ba a bayyana ba ko rauni na tsoka ya faru. Musamman idan suna tare da zazzabi ko zazzabi.

Jiyya tare da Atoris® na iya haifar da cutar sankara, wanda wani lokacin yana tare da rhabdomyolysis, wanda ke haifar da gazawar cutar koda. Hadarin wannan rikitarwa yana ƙaruwa yayin ɗauka ɗaya ko fiye na kwayoyi masu zuwa tare da Atoriseri: magungunan fibroic acid, niacin, cyclosporine, nefazodone, wasu ƙwayoyin rigakafi, magungunan hana ƙwayoyin cuta, da magungunan hana ƙwayoyin cuta.

A cikin bayyanar cututtukan cututtukan cututtukan zuciya, ana bada shawara cewa shawarar plasma na CPK ta ƙaddara. Tare da ƙaruwa sau 10 a cikin kusancin VHF na aikin KFK, ya kamata a dakatar da jiyya tare da Atoris®.

Akwai rahotanni na ci gaban atciic fasciitis tare da yin amfani da atorvastatin, duk da haka, haɗi tare da amfani da miyagun ƙwayoyi yana yiwuwa, amma har yanzu ba a tabbatar da hakan ba, ba a san etiology ba.

Yakamata a gargadi marassa lafiya cewa yakamata su nemi likita kai tsaye idan zafin da ba a bayyana ba ko rauni na tsoka ya faru, musamman idan suna tare da zazzabi ko zazzabi.

Atoris® ya ƙunshi lactose, sabili da haka amfani da marasa lafiya da rashi lactase, rashin haƙuri na lactose da cutar glucose-galactose malabsorption synde ta haɗu.

Tasiri a kan ikon tuka motoci da aiki tare da kayan aiki.

Ganin akwai yuwuwar rashin tsoro, yakamata a yi taka tsantsan yayin tuki motocin da wasu naúrorin fasaha waɗanda ke buƙatar haɓakar haɓaka da saurin halayen psychomotor.

Kwamfutar hannu 1 ya ƙunshi:

Aiki mai aiki: atorvastatin alli 10.36 mg, (daidai yake da 10 mg atorvastatin, bi da bi).

Fitowa: povidone - 5.8 mg, sodium lauryl sulfate - 2.9 mg, ƙwayar calcium - 31,84 mg, MCC - 29 mg, lactose monohydrate - 57.125 mg, ƙwayar sakinum (croscarmellose) - 7.25 mg, magnesium stearate - 0.725 mg.

Shell fim: Opadry II HP 85F28751 fari (polyvinyl barasa, titanium dioxide (E171), macrogol 3000, talc) - 4.35 mg.

Sashi da gudanarwa

A ciki, ba tare da cin abincin ba.

Kafin fara amfani da miyagun ƙwayoyi Atoris®, ya kamata a tura mai haƙuri zuwa abincin da ke tabbatar da raguwar yawan lipids a cikin jini, wanda dole ne a lura yayin duk jiyya tare da miyagun ƙwayoyi. Kafin farawa da jiyya, ya kamata kuyi ƙoƙarin cimma iko na hypercholesterolemia ta hanyar motsa jiki da asarar nauyi a cikin marasa lafiya tare da kiba, kazalika da magani don cututtukan da ke tattare da cutar.

Jiyya yana farawa tare da shawarar farawa na 10 MG. Yawan maganin yana bambanta daga 10 zuwa 80 MG sau ɗaya a rana kuma an zaɓi yin la'akari da farkon maida hankali na LDL-C, manufar farji da tasirin magani na mutum.

Ana iya daukar Atoris® sau ɗaya a kowane lokaci na rana, amma a lokaci guda kowace rana. Ana lura da tasirin warkewa bayan makonni 2 na magani, kuma mafi girman tasirin yana tasowa bayan makonni 4. Sabili da haka, sashi ba za a canza shi ba kafin makonni 4 bayan fara maganin a cikin kashi na baya.

A farkon farfajiya da / ko yayin karuwa a cikin kashi, yana da mahimmanci don saka idanu da yawan ƙwayar lipids a cikin jini na kowane mako na 2-4 kuma daidaita sashi gwargwado.

Primary (heterozygous gado da polygenic) hypercholesterolemia (nau'in IIa) da cakuda hyperlipidemia (nau'in IIb): lura yana farawa tare da shawarar farko na shawarar, wanda aka ƙaruwa bayan makonni 4, gwargwadon amsawar mai haƙuri. Matsakaicin adadin yau da kullun shine 80 MG.

Homozygous maganin gadoji: kewayon kashi ɗaya daidai yake da na sauran nau'in cututtukan cututtukan fata. An zaɓi kashi na farko akayi daban-daban, gwargwadon tsananin cutar. A cikin mafi yawan marasa lafiya tare da hyzycholesterolemia na homozygous, ana lura da ingantaccen sakamako tare da amfani da miyagun ƙwayoyi a cikin adadin yau da kullun na 80 MG (sau ɗaya). Ana amfani da Atoris® a matsayin maganin haɗin kai zuwa wasu hanyoyin magani (plasmapheresis) ko azaman babban magani idan magani tare da sauran hanyoyin ba zai yiwu ba.

Groupsungiyoyin haƙuri na musamman.

Tsofaffi marasa lafiya.

A cikin marasa lafiyar tsofaffi, kashi na Atoris® bai kamata a canza shi ba.

Paarancin aiki na haya.

Ba shi da tasiri a cikin taro na atorvastatin a cikin jini na plasma ko kuma digiri na raguwa a cikin taro na LDL-C tare da yin amfani da atorvastatin, sabili da haka, ba a buƙatar canza kashi na miyagun ƙwayoyi ba.

Rashin aikin hanta.

A cikin marasa lafiya da ke fama da aiki na hanta, taka tsantsan wajibi ne (saboda raguwa a cikin cire magunguna daga jiki). A irin wannan yanayin, yakamata a kula da sigogin asibiti da dakin gwaje-gwaje (sanya ido a kai a kai na ayyukan ACT da na AlT). Tare da haɓaka mai mahimmanci a cikin hanyoyin hepatic, ya kamata a rage kashi na Atoris® ko ya kamata a dakatar da magani.

Yi amfani dashi a hade tare da wasu kwayoyi.

Idan ya cancanta, yin amfani da cyclosporine na yau da kullun na maganin Atoris® bai kamata ya wuce 10 MG ba.

Atoris - cikakken bayani

Wakilin hypolipidem Atoris (Atoris) wani bangare ne na rukunan gumakan da ke hana aiki na enzyme a cikin hanta (HGM-CoA), wanda ke da alhakin samar da cholesterol.

Ana samar da miyagun ƙwayoyi a cikin nau'in kwamfutar hannu a cikin matakan daban-daban: 10 mg, 20 mg da 40 MG na kayan aiki na atorvastatin. Tabletaya daga cikin kwamfutar hannu ya ƙunshi ƙaramin adadin tsofaffin abubuwa - povidone, sodium lauryl sulfate, magnesium stearate, lactose monohydrate, da sauransu.

Hanyar aiwatar da miyagun ƙwayoyi yana da alaƙa da murƙushewar ƙwayar cholesterol da ƙara ƙarfin aiki na masu karɓa na LDL a cikin ƙwayoyin cuta da hanta. Bayan haka, masu karɓa na ɗaukar ƙananan ƙwayoyin LDL, suna cire su daga cikin jini. Don haka, akwai raguwar ƙwayoyin jini.

Likita ya umarci Atoris a cikin irin waɗannan halaye:

• marasa lafiya ba tare da bayyanin cututtukan zuciya na zuciya ba don rage hadarin infarction na zuciya, bugun jini, angina pectoris da buƙatar tsarin farfadowa na mahaifa,
• marasa lafiya da ke fama da rashin lafiyar insulin-da ke fama da rashin lafiyar insulin-mahaifa (nau'in 2) ba tare da bayyanin cututtukan zuciya na zuciya ba don rage yiwuwar bugun zuciya da bugun jini,
• marasa lafiya da ke nuna cututtukan zuciya da jijiyoyin zuciya don rage hadarin rashin mutuwa mai rauni, bugun zuciya da rashin mutuwa, angina pectoris, da bukatar farfadowa na mahaifa da kuma asibiti saboda rauni na zuciya,
• a matsayin ƙari ga abinci na musamman don na farko (dangi / wanda ba dangi ba) da gauraye (nau'in IIa da IIb) hypercholesterolemia,
• a matsayin ƙari ga abinci don hypertriglyceridemia (nau'in IV), dysbetalipoproteinemia na farko (nau'in III), da kuma hyzycholesterolemia na homozygous,
• marasa lafiya 10-17 shekara da haihuwa wanda ke da tarihin iyali na cututtukan zuciya na farko ko fiye da abubuwan biyu na ci gaban su.

Atoris yana da ƙananan adadin contraindications. Daga cikin su, ya zama dole a nuna alamar damuwa ga abubuwan da ke jikin allunan, daukar ciki da lokacin lactation, dysfunction hanta da kuma matakan haɓakawa na transaminases.

Abubuwan ƙarancin analogues da maye gurbin magunguna na atoris ga yara da manya

Atoris magani ne wanda aka shigo dashi. Analogues mai rahusa fiye da Atoris suna da abu iri ɗaya ko makamancin aiki, ana samarwa a ƙasashe daban-daban, gami da masana'antun gida. Magungunan da kanta a Rasha ya kai kimanin 400 - 1000 rubles. Wannan bambance-bambancen a cikin farashin yana faruwa ne saboda bambancin adadin allunan a cikin kunshin da kuma gwargwadon yawan aikin su.

Manuniya don amfani suna nuna rashin fahimta ga yawancin masu siyan kalmar hyperlipidemia. A zahiri, wannan yana nufin haɓaka matakin lipids a cikin jini (alal misali, ana iya kiran cholesterol, amma akwai abubuwa da yawa), waɗannan abubuwa ne masu narkewa kyauta cikin jini kuma suna iya haifar da jijiyoyin bugun jini.

Kasancewar su yana nuna cin zarafin mai. Magunguna na wannan nau'in na iya cire lipids daga jini kuma rage matakin su.

Increasedara yawan abubuwan aiki mai aiki ya dace wa marasa lafiya da matsanancin matakan cutar.

Analogs na samarwa na Rasha

Anaarancin magunguna na masana'antar ƙirar gida sun sami damar jimre wa hauhawar haɓakar lipid. Kuma ba koyaushe magunguna masu rahusa sun bambanta da halaye masu inganci ba. A cikin teburin da ke ƙasa mun lissafa waɗanda suka fi kowa.

Maƙerani na Yukren

Jerin analog ɗin da aka yi da Yukren ya ƙunshi shirye-shirye na halitta. Sauya tare da ƙarancin magani yana da kyau a farkon matakan cutar ko azaman ƙarin kayan aiki.

1. Karin maganin kwari. Magungunan, wanda aka kirkira bisa tushen kayan halitta, ya dace wa matasa da manya. Amincewa da darussan. Kudinsa yakai 210 rubles.
2. Aterovit. Yana taimakawa karfafa tasoshin jini da ƙananan cholesterol. Abun da ya shafi miyagun ƙwayoyi shine na halitta. Sun kashe 140 rubles.
3. Cardiochistin. An yi masa allurar rigakafin jini. Yana inganta lafiya tare da atherosclerosis. An haramta shan magani a lokacin daukar ciki da lokacin shayarwa. Kudinsa 200 rubles ne.
4. Cikakkiyar Omega Plus. Cikakken tushen Omega acid na nau'in 3 da 6. Normalizes aikin tsarin zuciya ne. Baya bada izinin samuwar jini. An gwada maganin a asibiti. Farashin a Rasha shine 330 rubles.
5. Dioscorea Plus. Yakan saukar da cholesterol jini kuma yana rage karfin jini. Yana kare tasoshin jini daga lalacewa. Dukkanin-halitta ne. Kudinta kusan 250 rubles ne.

Kwayoyin Belarusian

Kwayoyin halittar Belarusiya ba su da tsada. Waɗannan su ne waɗanda ke kusa da su waɗanda aka haɗa da bangarori daban-daban masu aiki da kuma irin wannan tsari na bayyanar jikin mai haƙuri.

Sauran analogues na kasashen waje

Magunguna da aka shigo da su sun fi tsada. Mafi kyawun zaɓi da aka jera don kowane shari'ar mutum ne. Yanke shawarar ta fi dacewa ku tafi tare da likita. Maganar Atoris suna da nasu halaye.

• Vasilip. An yi shi a Slovenia. Ya dace da marasa lafiya da masu ciwon sukari. Normalizes cholesterol, amma tare da abinci. Ya danganta da yawan allunan a cikin kunshin, farashinsa daga 160 zuwa 340 rubles.
• Zokor. An yi shi a Netherlands. Shan miyagun ƙwayoyi ya zama ya dace lokacin da ake fuskantar haɗarin kamuwa da cutar sankarar zuciya. Kwayoyin sunkai 750 rubles.
• Kanta. An yi shi a Burtaniya. Ya dace da marasa lafiya da atherosclerosis ko nau'ikan hypercholesterolemia.Farashin magani na magunguna daban-daban ya bambanta daga 700 zuwa 3600 rubles.
• Rosulip. An yi shi a Harshen Hungary. Bai bada izinin samuwar adon cholesterol ba. Ana sake shi ne kawai ta takardar sayan magani. Wani bambancin sashi na allunan yana farashi daga 700 zuwa 1200 rubles.
• Mertenil. An yi shi a Harshen. Ba a yi nazarin tasirin yara tare da wannan magani ba kuma an haramta shi don sanya shi ga yara. Yawancin sigogi suna kan siyarwa, farashin su yana farawa daga 700 rubles kuma ya kai 1400 rubles.
• Rosucard. Jamhuriyar Czech Abun da ke cikin miyagun ƙwayoyi ya haɗa da rosuvastatin abu mai aiki. Aikace-aikacen zai yiwu ne kawai bayan alƙawarin likita. Magani mai ƙarancin tsada ne, farashinsa bai wuce 500 rubles ba.

Yadda za a maye gurbin atoris yana da sauƙin warwarewa. Akwai da yawa analogues. Farashin su ya bambanta, jerin alamun suna da bambanci, akwai magunguna tare da hadaddun sakamako a jikin mutum, tabbas akwai waɗanda aka jagoranta.

Za'a iya zaɓin maganin da ya zama dole ne bayan cikakkun kewayon abubuwan da suka wajaba a cikin dakin gwaje-gwaje ko karatun asibiti.

Allunan Atoris: umarnin don amfani, sakamako masu illa, analogues, farashi, sake dubawa

Magungunan Atoris, umarnin don amfani da wanda aka ba wa masu karatunmu, yana cikin rukuni na magunguna masu rage ƙwaƙwalwar ƙwayar cuta, wanda shine ƙarni na uku na statins - magungunan da ke taimakawa rage yawan ƙwayoyin lipoproteins da yawa (LDL) - abin da ake kira "mummunan cholesterol" - a cikin membranes cell, kyallen da yanayin mahallin ( jini, lymph, ruwa na cerebrospinal, synovial da ruwa mai hade) na jikin mutum.

Amfani da magungunan wannan nau'in yana rage yiwuwar cutar zuciya da jijiyoyin jini a cikin marasa lafiya na ɓangaren na tsakiya, kodayake a cikin mutane waɗanda suka girmi shekaru saba'in wannan tsarin ba haka yake ba.

Ana bada shawarar kayan aiki don amfani kawai a lokuta inda hadaddun matakan kariya (biye da ƙarancin abinci na cholesterol, wasanni na yau da kullun da ayyukan don rage nauyin jiki) basu bayar da gudummawa ga daidaituwa na metabolism na lipid.

Bayanai game da abun da ke ciki, nau'i na saki da marufi

Atoris yana da nau'in sashi guda ɗaya kuma yana samuwa a cikin fararen - dan kadan biconvex - allunan zagaye tare da murfin fim. Abubuwan da ke aiki da wannan ƙwayar cuta shine atorvastatin.

Abunda ke cikin kowane kwamfutar hannu na iya zama: 10, 20, 30, 40, 60 da 80 MG.

An gabatar da ƙarin abubuwan haɗin abubuwan sunadarai:

• Microcrystalline cellulose,
• Sodium lauryl sulfate,
• Magnesium stearate,
• Carbon da ke karafa
• Lacose conohydrate,
• Povidone
• Sanatari
• Croscarmellose sodium.

Takar fim Opadry II an sanya ta:

• Talc,
• Titanium dioxide (ƙarin abinci na E171),
• Polyethylene glycol (a wasu kafofin ana kiran shi macrogol-3000 ko ƙarin abinci na E1521),
• Polyvinyl barasa

Tushen kwamfutar hannu akan lahani yana kama da farin farin abu mai laushi mai laushi. Kwantena tantanin halitta (blister) tare da allunan an sanya su a cikin kwali fakiti.

Ya danganta da adadin kaso na kayan aiki, kowane kunshin na iya ƙunsar daga allunan goma zuwa casa'in. Umarnin don amfani dole ne a lulluɓe a kowane kunshin tare da magani.

Fasali na magunguna

Magungunan atoris, wanda ke cikin rukunin statins, yana da tasirin lipid-lowering saboda ƙayyadaddun sashin aiki mai aiki, atorvastatin, don hana (rage gudu) ayyukan wani enzyme na musamman (HMG-CoA reductase), wanda ke ɗauka a cikin farkon matakan cholesterol kira wanda ƙwayoyin hanta ke gudana (hepatocytes )

Godiya ga shigarwar atorvastatin, adadin cholesterol da aka samar da hepatocytes an rage shi sosai, yana ba da kwarin gwiwa ga farkon karuwar sakamako mai karɓa a cikin adadin masu karɓa na LDL tare da ɗaukar lokaci guda da kuma amfani da ƙwayoyin lipoprotein low mai yawa wanda ke cikin jini.

A wannan yanayin, metabolism na lipoproteins, wanda ya haɗa da furotin apolipoprotein - furotin na apoB, wanda ke ɗaukar cholesterol "mara kyau" kuma masu karɓa daga LDL na ƙwayoyin hanta, suma suna ƙaruwa.

Sakamakon abubuwan da aka ambata a sama, gutsutsuren ƙwayoyin lipoproteins masu ƙarancin yawa, da zarar an ɗaure su, bayan an cire wani lokaci daga ƙwayar jini, wanda ke nufin shi ma yana rage girman ƙwayar lipoprotein low mai yawa.

Sakamakon wannan sakamako yana faruwa:

• Kusantar da kwayar halitta abubuwa - isoprenoids da aka kafa a jikin dan Adam daga acetic
• Acid da haɓakar haɓakar sel waɗanda ke haɓaka ƙwayoyin kwalliyar ciki,
• Ingarfafa nutsuwa mai dorewa ga jini,
• Rage ƙananan triglycerides, furotin apoB da ƙananan ƙwayoyin lipoprotein cholesterol,
• Increasearin haɓakar haɗuwa da apolipoprotein AI (furotin apoA-I) da kuma yawan lipoproteins mai yawa, waɗanda suke jigilar "kyawawan ƙwayoyin cholesterol",
• Rage ƙarancin jini na jini
• Inarfafawar matakai na coagulation da gluing (tari) na platelet,
• Inganta hemodynamics (motsi na jini ta hanyar tsarin tasoshin jini daga yankin mai matsin lamba zuwa ƙananan yankin),
• Normalization na jini coagulation tsarin,
• Tarewa da wuce haddi na ayyukan macrophages (sel wadanda ke da alhakin kamuwa da kwayoyin cuta, sel da suka mutu da kuma barbashi wadanda ba'asan su ga jikin mutum), wanda ke taimaka wajan hana hako abubuwa da ake kira plates ofherosclerotic.

Sakamakon farko na bayyanar atorvastatin ana lura da shi bayan sati biyu na shan maganin, yana isa mafi girman darajar bayan wata daya. A yayin gudanar da aikin likita, an tabbatar da cewa atoris maganin kwaya ne wanda zaku iya rage yiwuwar rikicewar ischemic, da buƙatar sake asibiti a cikin marasa lafiya da yawan mutuwar.

Pharmacokinetics

• Matsakaicin ƙwayar ƙwayar atoris a cikin jini na jini ana lura da sa'o'i 1-2 bayan shan allunan.
• Magungunan magunguna na atorvastatin basu dogara da jinsi ko shekarun marasa lafiya ba.
• An gano cewa a cikin jikin marasa lafiya da ke fama da cututtukan giya na hanta, adadin abin da ya faru na yawan haɗarin atorvastatin na iya zama sau goma sha shida fiye da na yau da kullun.
• Bayan cin abinci, adadin sha (sha) na miyagun ƙwayoyi yana raguwa kaɗan, ko da yake matakin ƙananan ƙwayoyin lipoprotein cholesterol baya canzawa kwata-kwata.
• Rashin bioavailability na atorvastatin, wanda ya fara wucewa ta hanta na mai haƙuri, yayi ƙasa da ƙasa: bai wuce 12% ba (an yi bayanin wannan ta hanyar yawan matakan metabolism). Tsarin bioavailability na tsarin tasirin hanawar atorvastatin akan ragewar HMG-CoA yana kusa da 30%.
• Dangantakar sashi mai aiki na miyagun ƙwayoyi tare da furotin jini na jini shine 98%.
• Atorvastatin baya shawo kan katangar-kwakwalwar jini, metabolism dinsa yakan faru ne a cikin tsarin hanta a sakamakon bayyanar cytochrome P4503A4. Ma'aikacin pharmacologically mai aiki wanda aka kafa sakamakon wannan tsari yana samar da babban (kusan kashi 70%) na aikin magungunan ƙwayoyin cutar Atoris, wanda zai kai tsawon awanni ashirin zuwa talatin.
• Rabin rayuwar miyagun ƙwayoyi kusan awa goma sha huɗu ne. Yawancin magungunan suna barin jikin mai haƙuri da bile, dan ƙaramin abu (kusan 45%) - tare da feces. Tare da fitsari, ba fiye da 2% na maganin ba a keɓe.

Atoris - analogues

Don rage matakin triglycerides, lipids da cholesterol a cikin jini, an tsara statins. Atoris kuma yana magana da su - ana buƙatar analogues na miyagun ƙwayoyi idan akwai rashin haƙuri ga wannan magani ko kuma, saboda wasu dalilai, ba zai yiwu ba siyan shi. Yana da mahimmanci a lura cewa yawancin kwayoyin halitta suna da rahusa.

Analogues na miyagun ƙwayoyi Atoris

An gabatar da shirye-shiryen da aka gabatar akan asalin sinadarin atorvastatin - wani abu da aka kirkira don rage yawan lipids a cikin jini. Atoris kuma yana haifar da tasirin cututtukan sclerotic a jikin bangon jijiyoyin jini, rage danko da yawan jini, da inganta halayyar jini, da rage hadarin kamuwa da cututtukan zuciya.

Kwayoyi masu zuwa suna da irin wannan sakamako kuma abun da ke ciki:

• Torvalip
• Tulip
• Torvas
• Kaya Yanar,
• Thorvacard
• TG-tor
• Torvazin
• Atorvastatin
• Liprimar
• Atorvox
• Lipoford
• Vazator
• Lipona
• Amvastan
• Astin
• Atocor
• Atorvacor
• Atotex
• Gagarinka,
• Atormak
• Lipodemin,
• Limistin
• Lipimax
• Vasocline
• Livostor
• Torvazin
• Lithuania,
• Mai jurewa
• Etset,
• Torzaks,
• Actastatin
• Abita
• Aztor
• Ciwon hanji
• Storvas
• Escolan
• Emstat
• Torvadak
• Lipitin
• Atrok.

Wanne yafi tasiri kuma yafi aiki mafi kyau - Atoris ko Torvakard?

Duk magungunan da aka yi la’akari da su an sanya su ne a kan aiki guda ɗaya ɗin, abin da ya haɗa ƙarin kayan aikin shima daidai suke. Masana lafiyar zuciya sunyi imani da cewa babu wani bambance-bambance masu mahimmanci tsakanin magungunan, kawai bambanci a cikin farashi shine Torvard ya kasance mai rahusa kaɗan, har ma da mafi girman maida hankali (40 MG).

Wanne ya fi kyau saya - Atorvastatin ko Atoris?

Waɗannan magungunan kuma suna da tsari iri ɗaya, sakin tsari da abubuwan da aka gyara. Atorvastatin ne mafi yawan lokuta ana fifita su, saboda yana da haƙƙin haƙuri kuma yana haifar da ƙananan sakamako masu illa. A wannan yanayin, wakili yana da tsada sosai fiye da Atoris, wanda aka bayyana shi ta babban digiri na tsarkake abubuwan da ke cikin allunan.

Krestor ko Atoris - Wanne ya fi kyau?

Magungunan farko da aka nuna sun dogara ne akan wani abu - rosuvastatin. Yana aiki daidai da Atoris, amma yana ɗaukar ƙananan sashi, tunda 5 MG na rosuvastatin yayi daidai da ƙarfin 10 MG na atorvastatin.

Don haka, ana ɗaukar Krestor a matsayin magani mafi dacewa, wanda za'a iya ɗauka ba sau da yawa. A lokaci guda, yana da tsada fiye da Atoris, kusan sau 2.5.

Effectivearin inganci Atoris ko Liprimar, kuma menene mafi kyau saya?

Ana yin magunguna masu kwatancen akan atorvastatin. Daga cikin fa'idodin Liprimar yana da daraja a lura:

• Yawan adadin magungunan da aka samu (10, 20, 40 da 80 mg),
• ingancin tsabtace kayan abinci, wanda ke bayar da riskarancin haɗarin sakamako masu illa,
• kyakkyawan haƙuri
• babban bioavailability da digestibility.

Koyaya, Liprimar ba shi da wuya a wajabta shi saboda farashin mai girma, ya ninka 4.5 sau da yawa fiye da Atoris.

Menene mafi kyawun abin sha - Atoris ko Simvastatin?

Magungunan da aka gabatar suna da kayan abinci masu aiki daban-daban, kuma don cimma burin da ake so na warkewar simvastatin, ana buƙatar 20 MG, yayin da atorvastatin ke buƙatar 10 MG.

Babu wani bambanci na musamman tsakanin kwayoyi, sai dai nau'in farashin su. Atoris yakai kusan sau 4 mafi tsada. Lokacin zabar tsakanin sa da Simvastatin yana da mahimmanci a la'akari da halaye na mutum na mai haƙuri, kasancewar halayen rashin lafiyan mutum da ƙin jin daɗin abubuwan da ke cikin magungunan.

Roxer ko Atoris - Wanne ya fi kyau?

Haɗin waɗannan magunguna ma daban ne, roxuvastatin shine tushen Roxers. Kamar yadda aka riga aka nuna, wannan abun yafi dacewa, tunda yana da inganci, baya buƙatar kulawa da yawan lokaci. Yawancin likitoci suna ba da Roxer sau da yawa, saboda wannan magani, ban da tasiri, yana da sauƙin araha, sau 2 yana da rahusa fiye da Atoris.

Atoris analogues da farashin

Kafin fara jinya tare da Atoris®, dole ne a tsara mai haƙuri da daidaitaccen tsarin abinci mai gina jiki, wanda dole ne ya bi yayin duk lokacin kulawa.

Ana iya lura da haɓaka ayyukan enzymes na hepatic a cikin jijiyoyin jini yayin kulawa tare da Atoris®. Wannan ƙaruwa yawanci ƙarami ne kuma bashi da mahimmancin asibiti.

Koyaya, ana bada shawara don saka idanu akan ayyukan ayyukan enzymes na hanta a cikin ƙwayar jini kafin jiyya, bayan makonni 6 da 12 kuma tare da haɓaka kashi na atorvastatin.

Idan akwai ƙaruwa sau uku a cikin ayyukan ACT da / ko alT dangi da HBV, ya kamata a dakatar da jiyya tare da Atoris®.

Atorvastatin na iya haifar da karuwa a cikin ayyukan CPK da aminotransferases.

A cikin mata masu haihuwa da ba sa amfani da abin da aka hana, amma ba a shawarar amfani da Atoris®. Idan mara lafiyar yana shirin daukar ciki, to ya kamata ta daina shan Atoris® aƙalla wata ɗaya kafin shirin yin ciki.

Yakamata a gargadi marassa lafiya cewa yakamata su nemi likita kai tsaye idan zafin da ba a bayyana ba ko rauni na tsoka ya faru. Musamman idan suna tare da zazzabi ko zazzabi.

Jiyya tare da Atoris® na iya haifar da cutar sankara, wanda wani lokacin yana tare da rhabdomyolysis, wanda ke haifar da gazawar cutar koda.

Hadarin wannan rikitarwa yana ƙaruwa yayin ɗauka ɗaya ko fiye na kwayoyi masu zuwa tare da Atoriseri: magungunan fibroic acid, niacin, cyclosporine, nefazodone, wasu ƙwayoyin rigakafi, magungunan hana ƙwayoyin cuta, da magungunan hana ƙwayoyin cuta.

A cikin bayyanar cututtukan cututtukan cututtukan zuciya, ana bada shawara cewa shawarar plasma na CPK ta ƙaddara. Tare da ƙaruwa sau 10 a cikin kusancin VHF na aikin KFK, ya kamata a dakatar da jiyya tare da Atoris®.

Akwai rahotanni na ci gaban atciic fasciitis tare da yin amfani da atorvastatin, duk da haka, haɗi tare da amfani da miyagun ƙwayoyi yana yiwuwa, amma har yanzu ba a tabbatar da hakan ba, ba a san etiology ba.

Yakamata a gargadi marassa lafiya cewa yakamata su nemi likita kai tsaye idan zafin da ba a bayyana ba ko rauni na tsoka ya faru, musamman idan suna tare da zazzabi ko zazzabi.

Atoris® ya ƙunshi lactose, sabili da haka amfani da marasa lafiya da rashi lactase, rashin haƙuri na lactose da cutar glucose-galactose malabsorption synde ta haɗu.

Tasiri a kan ikon tuka motoci da aiki tare da kayan aiki.

Ganin akwai yuwuwar rashin tsoro, yakamata a yi taka tsantsan yayin tuki motocin da wasu naúrorin fasaha waɗanda ke buƙatar haɓakar haɓaka da saurin halayen psychomotor.

Atoris: umarnin don amfani, analogues da bita

Atorvastatin yana rage yawan ƙwayoyin plasma cholesterol da lipoprotein ta hanyar hana GMK-CoA reductase, daga baya kuma ta hanyar biosynthesis na cholesterol a cikin hanta, sannan kuma yana ƙara yawan masu karɓar hepatic LDL akan farfajiyar tantanin halitta, wanda ke haifar da karuwar haɓakawa da LDL catabolism.

Yana rage samuwar LDL da yawan adadin ƙwayoyin LDL. Atoris yana haifar da karuwa mai ɗorewa a cikin ayyukan masu karɓar LDL a hade tare da canje-canje masu kyau a cikin ingancin ƙwayar LDL wanda kewaya.

Da kyau rage LDL cholesterol a cikin marasa lafiya tare da homozygous familial hypercholesterolemia, kuma wannan rukuni ne wanda bai ba da amsa koyaushe game da ilimin hypoliplera ba.

A cikin kalmomi masu sauƙi, yin amfani da Atoris yana taimakawa dakatar da samar da cholesterol a cikin jiki, rage yawan ƙananan ƙwayoyin lipoprotein cholesterol a cikin hanta.

Tasirin warkewa yana tasowa makonni 2 bayan fara maganin, ana samun sakamako mafi girma bayan makonni 4. Kafin fara magani, ya kamata a tura mai haƙuri zuwa abincin rage rage kiba, wanda dole ne a lura dashi lokacin da ake amfani da magani.

Atoris yana samuwa a cikin kwamfutar hannu tare da atorvastatin a cikin girma na 10, 20 da 40 mg a kowace kwamfutar hannu.

Alamu don amfani

Menene taimaka Atoris daga? Adana magungunan a cikin halaye masu zuwa:

• don lura da marasa lafiya tare da firamare (nau'in 2a da 2b) da kuma cudewar hyperlipidemia.
• an nuna kulawa da miyagun ƙwayoyi ga marasa lafiya tare da familialus hyzycholesterolemia tare da karuwa: cholesterol a gaba ɗaya, ƙarancin lipoprotein cholesterol, triglyceride ko apolipoprotein B.

Umarnin don amfani da Atoris, sashi

Ana ɗaukar magani a baka, ba tare da la'akari da abincin ba.

Yankin farawa shine 1 kwamfutar hannu na Atoris 10 MG kowace rana. Dangane da umarnin, sashi na miyagun ƙwayoyi ya bambanta daga 10 MG zuwa 80 MG sau ɗaya a rana, kuma an zaɓi yin la'akari da matakin farko na LDL-C, manufar farfaɗiya da tasirin magani na mutum. Iswararren likitan yana zaban maganin ne, la'akari da sakamakon gwajin da matakin farko na cholesterol.

A farkon farfajiya da / ko yayin karuwa a cikin kashi, yana da mahimmanci don saka idanu cikin abubuwan da ke cikin ƙwayar plasma a kowane mako na 2-4 kuma daidaita sashi gwargwado.

A cikin firamare (heterozygous hereditary da polygenic) hypercholesterolemia (nau'in IIa) da cakuda hyperlipidemia (nau'in IIb), jiyya yana farawa tare da shawarar farko na shawarar, wanda aka haɓaka bayan makonni 4 dangane da amsawar mai haƙuri. Matsakaicin adadin yau da kullun shine 80 MG.

Ga tsofaffi marasa lafiya da marasa lafiya da ke fama da rauni na aiki, ba a buƙatar daidaita sashi.

A cikin marasa lafiya da ke fama da aikin hanta, an wajabta magunguna tare da taka tsantsan dangane da jinkirin kawar da miyagun ƙwayoyi daga jikin mutum.

Side effects

Dangane da umarnin yin amfani da, ƙarar Atoris zai iya haɗuwa da waɗannan sakamako masu illa:

• Daga psyche: rashin jin daɗi, damuwa ta bacci, gami da rashin bacci da yawan bacci.
• Daga tsarin rigakafi: halayen rashin lafiyan, anaphylaxis (gami da girgiza ƙwayar anaphylactic).
• Rashin daidaituwa na metabolism: hyperglycemia, hypoglycemia, karin nauyi, anorexia, ciwon sukari mellitus.
• Daga tsarin haihuwa da gabobin dabbobi masu shaye shaye: lalatawar jima'i, rashin ƙarfi, gynecomastia.
• Daga tsarin juyayi: ciwon kai, paresthesia, dizziness, hypesthesia, dysgeusia, amnesia, neuropathy na gefe.
• Daga tsarin numfashi: cutar huhu na ciki, amai da gudawa, hancin hanci.
• Abun ciki da infestations: nasopharyngitis, cututtukan urinary tract.
• Daga tsarin jini da tsarin lymphatic: thrombocytopenia.
• Daga gefen kwayoyin hangen nesa: hangen nesa mai ruhi, raunin gani.
• Daga tsarin zuciya: bugun jini.
• A wani ɓangaren ɓangaren ji mai jijiya: tinnitus, raunin ji.
• Daga narkewa kamar jijiyoyi: maƙarƙashiya, flatulence, dyspepsia, tashin zuciya, zawo, amai, jin zafi a cikin manya da ƙananan ciki, belching, pancreatitis.
• Daga tsarin hepatobiliary: hepatitis, cholestasis, gazawar hanta.
• A wani ɓangaren fata da ƙwayoyin subcutaneous: urticaria, fatar fata, itching, alopecia, angioedema, bullous dermatitis, ciki har da exudative erythema, Stevens-Johnson syndrome, mai guba da ƙwayoyin cutar necrolysis, guba da jijiyoyin jiki.
• Daga cikin tsarin musculoskeletal: myalgia, arthralgia, raunin hannu, ƙwanƙwalwar tsoka, huɗar haɗin gwiwa, ciwon baya, ciwon wuya, rauni na tsoka, myopathy, myositis, rhabdomyolysis, tendonopathy (wani lokacin rikicewar da jijiya ta fashe).
• Rashin rikice-rikice na yau da kullun: malaise, asthenia, ciwon kirji, yanki na ciki, gajiya, zazzabi.

Contraindications

Atoris yana cikin abubuwan da ke tafe:

• mutum mai haƙuri zuwa ga abubuwan da ke tattare da kwayoyi,
• galactosemia,
• malabsorption na glucose galactose,
• karancin maganin lactose,
• m koda cuta,
• tsoka tsoka,
• ciki
• nono
• shekaru har zuwa shekaru 10.

Ya kamata a dauki hankali tare da shan giya, cutar hanta. Wannan rukunin ya kuma ƙunshi mutanen da ayyukan sana'arsu ke da alaƙa da tuki motoci da wasu keɓaɓɓun hanyoyin.

Yawan abin sama da ya kamata

Game da yawan abin sama da ya kamata, ya kamata a bayyanar da cututtukan da suka kamata kuma a tallafa musu. Wajibi ne don sarrafa aikin hanta da aikin CPK a cikin jini. Hemodialysis ba shi da tasiri. Babu takamaiman maganin rigakafi.

Ana sayar da magungunan Atoris, farashi a cikin kantin magunguna

Idan ya cancanta, za'a iya maye gurbin Atoris tare da analog na abu mai aiki - waɗannan magunguna ne:

Lokacin zabar analogues, yana da mahimmanci a fahimci cewa umarnin don amfani da Atoris, farashin da sake dubawa na kwayoyi tare da tasirin irin wannan ba su amfani. Yana da mahimmanci don samun shawarar likita kuma kada kuyi canjin magani mai yanci.

Adana a zazzabi da bai wuce 25 ° C. Rayuwar shelf shine shekaru 2. A cikin kantin magunguna, ana siyar da shi ta hanyar sayan magani.

Akwai ra'ayoyi daban-daban game da Atoris, kamar yadda mutane da yawa suka ce babban farashin maganin yana barata ta hanyar inganci da haƙuri mai kyau.

An lura cewa yayin aikin jiyya, yakamata a bi umarnin likita game da abinci da aikin jiki, kuma lokacin zaba da daidaita sashi, yakamata ayi la'akari da yawaitar lipoproteins mai yawa.

A cewar wasu masu amfani, miyagun ƙwayoyi ba shi da tasirin warkewa da ta dace kuma yana da haƙuri da haƙuri, yana haifar da mummunan sakamako.

Atoris analogues masu rahusa ne

Don rage matakin lipids a cikin jini, likitoci suna amfani da magunguna daban-daban, daga cikinsu Atoris da maganin ta analogues sun shahara sosai. Suna neman su rage cholesterol na jini, ta hakan zasu inganta rayuwar mutum gaba daya.

Game da magani

Ana samar da allunan Atoris a Slovenia. Wannan magani yana cikin nau'in “statins” kuma an wajabta shi ga marasa lafiya don rage adadin lipoproteins-low mai yawa (ƙwayoyin kwayoyi masu haɗari) a cikin jiki.

Atorvastatin shine babban maganin. Penetrating ta hanyar jini zuwa cikin kashin hanta, atorvastatin yana dakatar da kwayar halittar cholesterol daga hanta hanta.

A kan wannan yanayin, a cikin jiki yana fara amfani da lipoproteins waɗanda suka shiga cikin jini, suna da ƙananan kaso na yawa.

Sakamakon wannan, ingancin Atoris da analogues, waɗanda suke da irin wannan aikin aiwatarwa, yana ƙaruwa.

Cire atherogenic lipids na Atoris baya haifar da barkewar karshen wannan a jikin bangon jijiyoyin jini. A lokaci guda, atherosclerosis baya haɓakawa kuma ƙwayar jini ba ta haifar. Idan ischemia ta sami ci gaba a jikin mutum, shan Atoris da misalincinta yana haifar da raguwa cikin haɗarin bugun zuciya da bugun zuciya.

Hanyar sarrafawa ta Atoris da alamun ana amfani da ita ita ce nuna rashin amfanin magani kamar yadda likitan halartar ya tsara.

Yawancin lokaci, dangane da yanayin jiki da tsarin zuciya da jijiyoyin jini, likita ya ƙayyade mahimmancin sashi na maganin don inganta rayuwa.

Mafi sau da yawa, Atoris da kwatankwacinsa ana rubutasu cikin raguwa, tunda wannan yana rage yiwuwar tasirin sakamako.

Atoris analogues wanda ba ƙasa da tasiri ga maganin da kansa an yi amfani dashi a cikin aikin likita sama da shekaru goma. An tabbatar da wannan ta hanyar ingantattun dubarun likitoci da masu haƙuri. Tare da hypercholesterolemia, Atoris da analogues na iya rage cholesterol zuwa matakin da aka yarda da shi na ɗan gajeren lokaci, yayin da rage nauyin a kan zuciya.

Har zuwa yau, yawancin likitocin Atoris sun sami nasarar amfani da likitoci don rage cholesterol na jini. A Rasha, a kan shelf na kantin magunguna, ana gabatar da magungunan masu dacewa ba wai kawai a cikin kayan da aka shigo da su ba, har ma a cikin masana'antar cikin gida. Kowane analog na Atoris yana da takamaiman tsari da yanayin aikin, wanda likita dole ne yayi la'akari da shi kafin ya rubuta maganin.

Rosuvastatin

Rosuvastatin kwamfutar hannu ce ta baki mai haske ko ruwan hoda mai haske. Kamar yadda babban sinadaran aiki sune kwayoyin rosuvastatin, da yawa daga hankali. Baya ga ita, allunan suna dauke da:

• stearate magnesium
• sitaci zaruruwa
• colloidal nau'i na silicon dioxide,
• mai rikitarwa,
• fenti na musamman
• triacetin
• microcrystalline cellulose,
• titanium dioxide.

Abubuwan da ke aiki a cikin allunan da aka bayyana an nuna su ne ta hanyar dakatar da aikin enzymes ɗaiɗaikunsu waɗanda ke da alhakin halittar ƙwayoyin mevalonate a jiki. Na karshen, ana amfani da sinadarin cholesterol.

Ofungiyar magungunan, wanda Rosuvastatin nasa ne, yana dakatar da haɗin kwayoyin mevalonate.

Bayan aiwatar da aikinsa, an cire maganin ta hanyar da ba ta canzawa daga jiki tare da jijiyoyi.

Ana ƙaddamar da anael-lowering analogue, wanda shine rosuvastatin, an wajabta ga marasa lafiya da:

• ainihin hanyar hypercholesterolemia,
• sabar, kamar,
• homozygous (dangi) yanayin hypercholesterolemia.

Sashi na abu mai aiki yayin shan analog ana koyaushe ne ta likita don rage haɗarin haɓaka rikitarwa na atherosclerosis. Rosuvastatin ne sau da yawa ana tsara shi ga marasa lafiya a cikin tsufa, saboda a wannan lokacin ƙwayar katakon jirgin ruwa da yawa suna da mafi ƙarancin diamita, tunda an lulluɓe su da cholesterol

Gicciye wani ɗan tebur ne mai ruwan hoda wanda yake ɗauke da adadin kuzarin rosuvastatin mai kauri. Shine wanda ya aiwatar da babban aikin magani. Cutar da hankali akan abu mai amfani lokacin shan Krestor likita ne ya wajabta shi, bayan binciken da ya dace.

Magungunan yana da inganci don hypercholesterolemia, har ma da hypertriglyceridemia.

Hakanan, ana amfani da maganin don magance mellitus-non-insulin-dogara da ciwon sukari mellitus. Halakar miyagun ƙwayoyi yana faruwa a cikin ƙwayoyin hanta, tare da wucewa daga jiki.

Anauki Analog ya kamata a dosed da ruwa kadan. Dokta da likitan mata sun karu da yawa kuma sun tsara shi ne bayan gwaji na musamman game da tsarin kewaya mahaifa. Kai kai tsaye ta hanyar Krestor yana da haɗari ga lafiyar, saboda yana iya haifar da sakamako masu illa idan aka sami ƙarin yawan sha da yawa.

Cardiomagnyl

Cardiomagnyl wani nau'in analogues ne na Atoris. Abubuwan da ke aiki sune kwayoyin acetylsalicylic acid tare da magnesium hydroxide. Anara yawan ayyukan "mummunan ƙwayar cholesterol" a cikin jini yana nuna nadin Cardiomagnyl ta likita zuwa mara lafiya!

Shan wannan magani yana da alaƙa da haɓaka yiwuwar haɓaka ƙwayoyin ƙwayoyin ƙwayoyin jijiyoyin ƙwayoyin jijiyoyin jini a cikin jiki. Wannan na faruwa lokacin da:

• m tsarin angina pectoris,
• ciwon sukari ci gaba,
• matsanancin nauyin jiki
• hauhawar jini
• infarction na zuciya.

Cardiomagnyl yana cikin contraindicated a cikin mutane fama da:

• alerji ga miyagun ƙwayoyi,
• basur,
• na ciki,
• rashi a cikin jikin K-bitamin,
• erosive da ulcerative pathologies a cikin gabobin narkewa,
• mai tsanani digiri na renal gazawar.

Ba a yarda da Cardiomagnyl ta hanyar mutanen da ke shan wahala daga rashin haƙuri na mutum zuwa ga kwayoyin acetylsalicylic acid tare da magnesium hydroxide, da kuma lokacin daukar ciki a cikin lokacin lactation.

Simvastatin

Atoris ko simvastatin yafi tasiri? Simvastatin magani ne mai daukewar jini wanda ya ƙunshi adadin adadin kayan suna iri ɗaya. An wajabta maganin don marasa lafiya da ke fama da babban abun ciki na ƙwayoyin ƙwayar lipid a cikin jini.

Sakamakon haka, babu tarin abubuwan tara mai guba a jiki. Tare da babban tasiri na miyagun ƙwayoyi, ƙwayar tana da farashi mai karɓa, wanda ya sa ya zama sananne a tsakanin jama'a. Haɓaka cutar ɗan adam na mutum alama ce ta dakatar da shan wannan magani.

Atoris ko Atorvastatin: Wanne ya fi kyau? Kafin zaɓar maganin ƙirar Atoris, ya kamata ka nemi likitanka wanda, bayan cikakken nazarin jikin mutum, zai iya ba da magani mai lafiya da ingantaccen haƙuri ga mai haƙuri.

Muna ba da shawarar shi! Don jiyya da rigakafin Cutar cututtuka da magunguna, masu karatunmu suna amfani da hanyar yin azumin da ba a yin tiyata da manyan likitocin Rasha suka gabatar, wanda ya yanke shawarar tsayayya da rashin samar da magunguna tare da gabatar da wani magani wanda yake da gaske. Mun san wannan dabarar kuma mun yanke shawarar ba da shi ga hankalin ku.

Atoris: umarnin don amfani, analogues, farashi, sake dubawa

Atoris yana ɗaya daga cikin sunayen kasuwanci na atorvastatin da kamfanin Slovenian Krka ya samar. Daga cikin sauran kwayoyin, wannan magani ya shahara sosai a cikin ingancinsa.

An wajabta Atoris don rage ƙwayar cholesterol, "lahani" na lipoproteins, triglycerides, kazalika da ƙara haɗuwa da "lipoproteins masu kyau.

Umarnin ya nuna cewa masu sauraron maganin Atoris sune mutane masu fama da cututtukan zuciya, da cututtukan zuciya da na zuciya (CHD), da kuma ciwon suga.

Abun ciki, sakin saki

Atoris kwamfutar hannu ce da ke ɗauke da milligram 10, 20, 30, 60, ko 80 na abubuwan da ke aiki. Round, convex, fari. A kan Laifi - mai yawa, fari.

Aiki mai aiki na Atoris shine alli na atorvastatin. Baya ga shi, abun da ke tattare da miyagun ƙwayoyi ya haɗa da: povidone, sodium lauryl sulfate, carbonate carbonate, cellulose, lactose monohydrate, croscarmellose, magnesium stearate. Kowace kwamfutar hannu an rufe shi da Opadry 2.

Atoris: alamomi don amfani

Kafin ɗaukar maganin, an tura mai haƙuri zuwa abincin da ke rage haɗarin cholesterol, jinin LDL. Dole ne a lura da shi tsawon lokacin kulawa. Rashin kula da abincin yana da muhimmanci yana rage ko lalata ingancin aikin atorvastatin.

Dangane da umarnin, ana amfani da allunan Atoris don bi da:

• homo-, heterozygous da iyali da kuma rashin familial hypercholesterolemia,
• hade da cututtukan zuciya,
• dysbetalipoproteinemia,
• familial hypertriglyceridemia.

Hakanan an wajabta wa Atoris rigakafin cututtukan zuciya. Sakamakon magungunan antiatherogenic na miyagun ƙwayoyi:

• rage mace-mace daga cututtukan zuciya,
• na rage yiwuwar bugun zuciya, bugun jini,
• yana hana harin angina,
• rage yawan marasa lafiya da ke buƙatar tiyata.

Hanyar aikace-aikacen, sashi

Ana ɗaukar allunan Ator sau ɗaya / rana kafin lokacin barci, kafin, bayan ko tare da abinci. Yana da kyau a sha maganin a lokaci guda.

Me yasa yake da mahimmanci a ɗauki Atoris da yamma? A dare, hanta tana ɗaukar matsakaicin sinadarin cholesterol. Idan kun manta shan kwaya, kuyi shi da wuri-wuri.

Tsallake alƙawari guda ɗaya idan an rage ƙasa da sa'o'i 12 har zuwa na gaba. A lokaci guda, kashi na maganin ba ya buƙatar ƙara.

Matsakaicin maganin da aka ba da shawarar shine 10-80 MG. Lokacin zabar sashi na Atoris, matakin farko na cholesterol, LDL, kasancewar matsalolin haɗin gwiwa, da kuma amfani da wasu magunguna ana yin la'akari.

Jiyya yana farawa da ƙananan allurai na maganin (10-20 mg). Bayan makonni huɗu, likita ya bincika tasirin canje-canje a cikin cholesterol, lipoproteins. Idan ba a cimma sakamako da ake so ba, ana ƙaruwa da ƙwayar Atoris. Tare da low cholesterol, allunan tare da ƙananan taro na abu mai aiki ana wajabta su.

Don daidaita cholesterol, marasa lafiya waɗanda ke ɗaukar erythromycin, clarithromycin, lopinavir, ritonavir, Atoris an wajabta su a cikin adadin da bai wuce 20 MG ba.

A duk lokacin da ake yin magani, ya zama dole don sarrafa matakin cholesterol, LDL, VLDL, triglycerides, hanta, samfuran koda, CC. Wannan yana taimakawa kimantawa game da martanin jikin mutum game da amfanin Atoris, da kuma lura da haɓaka sakamako masu illa a cikin lokaci.

Haɗa kai

Yin amfani da allunan Atoris lokaci guda tare da wasu kwayoyi yana da mummunan sakamako ko ƙarancin ɗayan ɗayansu.

Ba'a wajabta maganin ba ga mutanen da suka sha:

• magungunan antifungal na kungiyar azole,
• wasu kwayoyin rigakafi (cyclosporine, telithromycin),
• gemfibrozil
• Abubuwan kariya na kwayar cutar HIV (ritonavir, lopinavir),
• fusidic acid
• sha ruwan innabi.

Wasu magunguna, lokacin ɗauka tare da Atoris, suna buƙatar daidaita sashi. Lissafinsu suna cikin ɓangaren "Hanyar aikace-aikace da sashi."