Kwayoyi mafi kyau don rage ƙwayar cholesterol: jerin da farashin

Cholesterol - Aljani ne mai yawan kitse, wani hadadden kwayoyin halitta da ake samu a jikin membranes na kwayoyin halittu.

Sau da yawa ana amfani da tsinkaye guda biyu - cholesterolda cholesterol. Mene ne bambanci tsakanin su biyun? A zahiri, wannan sunan abu guda ne, kawai a cikin littattafan likitanci kalmar "cholesterol"Tun daga ƙarshen"ol"Yana nuna alaƙar da ke da giya. Wannan abu yana da alhakin samar da ƙarfi. cell membranes.

Amma idan matakin ƙwayar cholesterol a jikin mutum ya karu, toshewar ƙwayoyin cholesterol a cikin ganuwar tasoshin, wanda, fatattaka, ƙirƙirar yanayi mai dacewa don samuwar jini clots. Quesunƙwasa hanyoyi suna toshe layin jirgin ruwa.

Sabili da haka, bayan bincike game da cholesterol, likita, idan ya cancanta, ya yanke shawarar abin da zai yi da cholesterol. Idan ƙirar bincike game da cholesterol tana nuna babban adadinta, sau da yawa kwararren likita ya tsara magunguna masu tsada - gumaka, waɗanda aka tsara don hana cututtuka na tsarin zuciya. Yana da mahimmanci likita ya bayyana cewa bayan alƙawarin, mai haƙuri yana buƙatar shan irin waɗannan allunan a koyaushe, kamar yadda umarnin ya bayar da shawarar.

Amma magungunan anticholesterol suna da wasu sakamako masu illa, waɗanda likitoci ya kamata su gargaɗi marasa lafiya game da, suna bayanin yadda za a sha magungunan kwayoyi daidai.

Sabili da haka, kowane mutumin da ke da tasirin cholesterol mafi girma dole ne ya yanke shawara ko ya sha irin waɗannan kwayoyi.

A halin yanzu, ana ba da manyan rukunoni biyu na magungunan cholesterol: gumakada fibrates. Bugu da kari, masana sun bada shawarar cewa mara lafiya ya cinye Cutar Lipoic da Omega 3. Abubuwan da ke biyo baya sune magungunan da ake amfani dasu don rage cholesterol. Koyaya, yin amfani dasu shine kawai bayan jarrabawa da alƙawarin likita.

Statins don rage cholesterol

Kafin shan irin waɗannan kwayoyi, kuna buƙatar sanin menene statins - menene, amfaninsu da lahanta da irin waɗannan kwayoyi, da sauransu Stat Statins sune sinadarai waɗanda ke rage samarwa jikin. enzymesda ake buƙata don aiwatar da ƙwayar cholesterol.

A cikin umarnin irin waɗannan kwayoyi, zaka iya karanta masu zuwa:

• Rage ƙwayar ƙwayar plasma saboda hanawa HMG-CoA reductasekazalika da rage kwayar cutar cholesterol a cikin hanta.
• Rage matakan cholesterol a cikin mutanen da ke wahala Iyalin hypercholesterolemia na hyzygous, wanda ba amenable ba ne don maganin cututtukan ƙwaƙwalwar ƙwayoyi.
• Tsarin aikinsu yana rage jimlar cholesterol da kashi 30-45%, “mai cutarwa” - 40-60%.
• Lokacin daukar matakin statins HDL cholesterol da basarashin Aya tashi.
• Magungunan suna rage yiwuwar rikicewar ischemic da 15%, musamman, bisa ga ƙarshen binciken masana lafiyar zuciya, haɗarin angina pectorisda infarction na zuciyaraguwa da 25%.
• Babu tasirin mutagenic da carcinogenic.

Side effects

Bayan ɗauka, za a iya lura da mummunan sakamako masu illa:

• Sakamakon sakamako na yau da kullun: asthenia, rashin bacci, ciwon kai, maƙarƙashiya, tashin zuciyaciwon ciki zawo, myalgia, rashin tsoro.
• Tsarin narkewa: zawo, amai, hepatitis, maganin ciwon huhuJazzice cholestatic anorexia.
• Tsarin ciki: tsananin farin ciki, amnesia, hypesthesia, malaise, paresthesia, neuropathy na yanki.
• Bayyanar bayyanar cututtuka: kurji da fata ƙaiƙayi, cututtukan mahaifa, anaphylaxis, exudative erythema, Cutar Lyell.
• Tsarin Musculoskeletal: ciwon baya myositis, katsewa, amosanin gabbai, ciwon kai.
• Halittar jini: thrombocytopenia.
• Hanyoyin tafiyar matakai: yawan haila, ciwon sukari mellitusnauyi kiba, rashin ƙarfina ciki edema.
• Mafi rikitarwa rikicewar magani shine rhabdomyolysisamma wannan yana faruwa a lokuta mafi wuya.

Wanene yake buƙatar ɗaukar gumaka?

Sanar da abin da mutum-mutumi, makircin talla da umarnin magunguna ke nuna hakan gumaka - Waɗannan magunguna ne masu inganci don rage ƙwayar cuta, wanda ke haɓaka darajar rayuwa gaba ɗaya, tare da rage yiwuwar ci gaba shanyewar jiki, infarction na zuciya. Dangane da haka, yin amfani da waɗannan kwayoyin a kowace rana hanya ce mai aminci don rage ƙwayar cholesterol.

Amma a zahiri, har zuwa yau babu takamaiman bayani game da ko dai kula da marasa lafiyar da irin waɗannan magunguna ke da aminci da inganci. Tabbas, wasu masu binciken sunyi da'awar cewa haɗarin cutar da tasirin sakamako ya wuce amfanin statins kamar yadda prophylactic da aka yi amfani dashi don hana cututtuka na tsarin zuciya. Har yanzu masana na ci gaba da gardama kan ko a dauki mutum-mutumi, tare da yin la'akari da ribobi da dabaru. Taron likitocin kusan kullum suna dauke ne da mahawara kan batun “Statins - Ribobi da Cons».

Amma, duk da haka, akwai wasu rukuni na marasa lafiya waɗanda tsoffin ƙwayoyin cuta ke wajaba a kansu.

Dole ne a yi amfani da sabon gumakan zamani:

• don rigakafin sakandare bayan bugun jiniko bugun zuciya,
• a sake yin tiyata a kan manyan jirgi da zuciya,
• a infarction na zuciyako m jijiyoyin zuciya,
• a na jijiyoyin zuciya jijiya cuta tare da karuwar yiwuwar bugun zuciya ko bugun zuciya.

Wato, ana nuna magungunan cholesterol don marasa lafiya na jijiyoyin jini domin kara yawan rayuwarsu. A wannan yanayin, don rage tasirin sakamako, likita ya kamata ya zaɓi maganin da ya dace, kula da sigogin ƙirar ƙwayoyin cuta. Idan an samu ƙaruwa sau 3 a transaminases, an soke statins.

Babu tabbas ko yana da kyau a iya ba da kwayoyi na wannan rukuni don irin waɗannan marasa lafiya:

Idan an tsara statins ga marasa lafiya da ciwon sukari, suna iya buƙatar ƙarin ƙwayoyin cuta don rage sukari a ciki jini, tunda a cikin irin waɗannan cututtukan marasa lafiya suna ƙaruwa da sukari. Magungunan don rage sukarin jini ya kamata a rubuta shi da likitan su kawai.

A halin yanzu, a cikin Rasha, ka'idoji don lura da yawancin cututtukan zuciya sun haɗa da amfani da statins. Amma, duk da gaskiyar cewa ƙaddamar da magunguna yana rage mace-mace, wannan ba lamari ne na wajabta magunguna ga duk mutanen da ke fama da cututtukan jijiyoyin zuciya ko hauhawar jini ba. Ba a yarda da amfani da su ba ga duk mutanen da suka riga sun shekara 45, ko duk waɗanda ke da ƙwayar cutar cholesterol.

Yana da mahimmanci a yi la'akari da jituwar waɗannan kwayoyi tare da wasu kwayoyi.

Idan ya cancanta, likita ya tsara wasu magunguna don maganin cututtukan zuciya tare da magungunan anticholesterol: Diroton, Damuwa, Propanorm da sauransu

Diroton(bangaren aiki - szamarin) ana amfani dashi don kula da hauhawar jini.

Damuwa(bangaren aiki - Bisoprolol hemifumarate) amfani dashi don warkarwa hauhawar jinibugun zuciya angina pectoris.

Jerin magungunan statin

Wanne kwayoyi suna da alaƙa da statins, kuma menene ayyukansu a cikin rage darajar cholesterol, za'a iya samu a tebur da ke ƙasa.

Yadda za a zabi statins?

Duk da duk sake dubawar da ake yi game da mutum-mutumi don rage yawan kwalaben, mai haƙuri ya kamata ya yanke shawara game da ko za a sha irin waɗannan magunguna, amma wannan ya kamata ne ya bi da shawarar kwararrun masana. Mahimmanci, da farko, ba sake dubawa ba, amma nadin likita.

Idan har yanzu mutum ya yanke shawarar ɗaukar siffofin mutum, to, zaɓin bai kamata ya zama farashin maganin ba, amma, da farko, kasancewar cututtukan fata.

Kula da kai, idan aka inganta ƙwayar cholesterol, babu wasu kwayoyi da za'a iya aiwatarwa. Jiyya tare da babban cholesterol da cututtukan metabolism cuta ne ta hanyar likitan zuciya ko likitan kwantar da hankali. A wannan yanayin, ƙwararren dole ne ya kimanta haɗarin masu zuwa:

• shekaru
• jinsi
• nauyi
• gaban munanan halaye,
• cututtuka na tsarin zuciya da jijiyoyin jini, wasu cututtuka (ciwon sukari mellitus, da sauransu).

Yana da mahimmanci a ɗauki mutum-mutumi a cikin kashin da likitanka ya umarta, alhali yana da mahimmanci a ɗauka gwajin jini na kwayoyin kamar yadda sau da yawa kamar yadda kwararru suka tsara.

A yayin taron cewa an bada magunguna masu tsada masu tsada, zaku iya tambayar likita don maye gurbinsa da magunguna masu rahusa. Koyaya, ana bada shawarar yin amfani da magunguna na asali, tunda ƙwararrun masanan da ke cikin gida suna da ƙarancin inganci fiye da na asali da ƙirar asali wanda ƙirar ƙasashen waje ke samarwa.

Wadanda suke da sha'awar ɗaukar bayanai game da ainihin fa'idodi da cutarwa na statins na cholesterol suna buƙatar la'akari da mahimman abubuwan da yawa don rage cutar da waɗannan kwayoyi.

Idan an tsara maganin ga tsofaffi marasa lafiya, ya kamata a lura cewa hadarin myopathiesyana ninka idan kun sha su tare da magunguna na hauhawar jini, gout, ciwon sukari mellitus.

A cikin cututtukan hanta na hanta, yana da kyau a ɗauki rosuvastatin a cikin ƙananan allurai, Hakanan zaka iya amfani Pravastatin (Fadawa) Wadannan kwayoyi suna ba da kariya ta hanta, amma yayin amfani da su, yakamata ku sha giya, kuma kuyi magani maganin rigakafi.

Tare da bayyanar kullun da raɗaɗin tsoka ko haɗarin lalacewar su, yana da kyau a yi amfani da Pravastatin, tun da ba mai guba da tsokoki.

Mutanen da ke fama da matsalolin koda ba za a ɗauke su ba. Fluvastin LeskolHakanan bai kamata a bugu ba Alli na Atorvastatin (Lipitor), kamar yadda waɗannan kwayoyi masu guba ne ga ƙodan.

Idan mai haƙuri ya nemi rage ƙwayar ƙwaƙwalwar low-density, ana bada shawara don amfani da nau'ikan statins daban-daban.

A halin yanzu, babu ingantaccen shaida cewa yana da kyau a ɗauki haɗarin "statins da nicotinic acid." Lokacin shan acid na nicotinic a cikin mutanen da ke da ciwon sukari, sukari na jini na iya raguwa, hare-hare na gout, zubar jini daga hanji shima zai yuwu, da alama yana ƙaruwa rhabdomyolysis da ciwon kai.

Nazarin kan sakamakon jijiyoyin jiki a jiki

Likitocin zuciya sun kirkiri mutum-mutumi na mutanen da ke fama da na jijiyoyin zuciya jijiya cuta, hauhawar jini, da samun ƙananan haɗarin cututtukan zuciya.

A halin yanzu, halayyar wannan nau'in magungunan ta canza ga wasu kwararru. Kodayake a Rasha har yanzu ba a gudanar da cikakken binciken bincike mai zaman kanta game da illolin ƙirar jikin mutum ba.

A halin yanzu, masana kimiyya na Kanada suna da'awar cewa bayan amfani da mutum-mutumi, hadarin kamala a cikin marasa lafiya ya karu da 57%, kuma ya ba da cewa mutumin ya sha wahala ciwon sukari, - by 82%. An tabbatar da irin wadannan bayanan masu karar ne ta hanyar aikin bincike.

Istswararrun kwararru sun yi nazarin sakamakon binciken kwasa-kwasan goma sha huɗu da aka gudanar don yin nazarin tasirin ƙirar jikin mutum.Conclusionarshensu shine mai biyo baya: lokacin shan wannan nau'in magani, da alama yiwuwar bugun jini da bugun zuciya ya ragu, amma idan aka yi lahanin sakamako masu illa, ba a basu takamaiman ga mutanen da basu taɓa fama da bugun jini ko cututtukan zuciya ba. Dangane da masu bincike, mutanen da suke shan irin wannan magunguna akai-akai suna haifar da sakamako masu illa:

Amma gabaɗaya, akwai mahangar ra'ayi daban-daban kan ko waɗannan magungunan suna da haɗari ko kuma amintattu.

• Masana kimiyya daga Jamus sun tabbatar da cewa da ƙarancin ƙwayar cuta, da yiwuwar haɓaka cutar kansa, cututtukan hanta da cututtuka masu yawa, har ma da mace-macen farkon haihuwa da kisan kai, ta haka ne ke tabbatar da cewa ƙananan ƙwayoyin cuta sun fi haɗari nesa.
• Masu bincike daga Amurka suna da'awar hakan bugun zuciya da shanyewar jiki ba saboda yawan cholesterol ba, amma saboda karancin magnesium a jiki.
• Statins na iya murkushe mahimmancin aikin cholesterol, wanda ke dawo da rikice-rikice a cikin ƙirar jikin. Domin jijiyar tsoka ta girma a cikin jiki, da kuma aikinta na yau da kullun, Kwayoyin kitsen mara nauyi, wato 'cholesterol' mara kyau. Idan aka lura da rashi, yana iya bayyana myalgia, tsoka dystrophy.
• Lokacin shan irin waɗannan kwayoyi, ana lalata ƙwayar cholesterol, bi da bi, da kuma haɓakawa mevalonate, wanda ba kawai tushen tushen cholesterol ba ne, har ma da wasu abubuwan abubuwa daban-daban. Suna yin ayyuka masu mahimmanci a cikin jiki, don haka raunin su na iya haifar da ci gaban cututtuka.
• Wannan rukunin magungunan yana kara saurin ci gaba ciwon sukari mellitus, kuma wannan cutar tana haifar da hauhawar ƙwayar cholesterol. Majiyoyi daban-daban suna da'awar cewa idan kun dauki statins na dogon lokaci, haɗarin ciwon sukari yana daga 10 zuwa 70%. A ƙarƙashin tasirin waɗannan kwayoyi a cikin tantanin halitta, maida hankali ne kan furotin na GLUT4, wanda ke da alhakin matakin glucose a cikin jini, yana raguwa. Masu binciken na Burtaniya sun nuna cewa shan irin wadannan magunguna na kara hadarin kamuwa da cutar siga a cikin mata bayan dakatarwar da mata tayi da kashi 70%.
• Abubuwan sakamako masu illa da ke haifar da ci gaba a hankali, bi da bi, mai haƙuri na iya lura da wannan ba nan da nan ba, wanda ke da haɗari tare da amfani da tsawan lokaci.
• Lokacin amfani da statins, an lura da tasiri akan hanta. Wadanda suke da kiba ko kuma suna yin rayuwa mai tazara, bayanin kula na dan wani lokaci wani cigaba a yanayin tasoshin. Amma tsawon lokaci, rikice-rikice a cikin jiki suna rushewa, wanda zai haifar da lalacewa a cikin hanyoyin tunani, musamman a cikin mutanen da suka tsufa.

Lokacin da mutumin da ke ƙasa da shekara 50 yana da babban matakin ƙwayar cholesterol, wannan yana nuna cewa rikice-rikice masu girma suna tasowa a cikin jikin mutum wanda ke buƙatar kulawa. A wasu ƙasashe, ana gabatar da shirye-shirye a matakin ƙasa wanda ke haɓaka rage ƙwayar cholesterol ta hanyar inganta salon rayuwa mai aiki, canza ka'idodin abinci, dakatar da jaraba na nicotine, da kuma yin amfani da mutum-mutumi.

Sakamakon haka, a cikin ƙasashe da yawa wannan hanyar ta “yi aiki”: mace-mace daga cututtukan zuciya sun ragu sosai. Koyaya, an yi imani da cewa dakatar da shan sigari, motsa jiki da canza menu hanya ce mafi kyau don tsawanta rayuwa fiye da amfani da kwayoyi waɗanda ke da cututtukan cututtukan cututtukan jiki.

Statins ga tsofaffi marasa lafiya

Daga cikin mahawara game da gaskiyar cewa tsofaffi yakamata su ɗauki statins kawai bayan yin la'akari sosai game da lahani da fa'idodi, zamu iya tuna karatun, wanda fiye da mutane dubu 3 suka haɗu da shekaru 60 waɗanda suka sha magungunan statin. Aƙalla 30% sun lura da bayyanar raunin ƙwayar tsoka, har da raguwar makamashi, gajiya mai ƙarfi, rauni.

Ciwon kirji ya fi tsanani a cikin wadanda suka fara shan irin waɗannan magunguna.A sakamakon haka, wannan yanayin yana rage yawan motsa jiki - yana da wahala mutane su iya motsa jiki, suyi tafiya, wanda a ƙarshe yana haifar da haɗarin haɗarin bugun jini da bugun zuciya. Bugu da ƙari, a cikin mutumin da ke da motsi kaɗan, nauyin jikin yana farawa da sannu-sannu, wanda kuma haɗarin cutar zuciya ne.

Fibrates: menene?

Shirye-shirye fibratesHakanan ya kasance yana rage ƙananan ƙwayar cuta. Wadannan magunguna magunguna ne. fibroic acid. Sun ɗaure zuwa bile acid, ta haka ne ke rage yawan ƙwayar cholesterol ta hanta.

Fenofibrates runtse matakin magani lipids, wanda, bi da bi, yana haifar da ƙananan ƙwayar cuta. Dangane da nazarin asibiti, yin amfani da fenofibrates yana rage cholesterol da 25%, triglycerides da 40-50%, kuma yana ƙara matakin abin da ake kira "mai kyau" cholesterol da 10-30%.

Umarnin don yin amfani da fenofibrates, ciprofibrates yana nuna cewa tare da babban cholesterol, waɗannan kwayoyi suna rage adadin adibas, da ƙananan cholesterol da triglycerides a cikin marasa lafiya da hypercholesterolemia.

Jerin ayyukan fenofibrates:

• Taykolor,
• Lipantil
• Fitowa 200,
• CiprofibrateLipanor
• Gemfibrozil.

Amma, kafin ka saya da shan irin waɗannan magunguna, ya kamata a ɗauka a zuciya cewa amfani da su yana haifar da bayyanar wasu sakamako masu illa. A matsayinka na mai mulki, yawancin cututtukan narkewar abinci ana bayyana su sau da yawa: rashin tsoro, dyspepsia, zawo, amai.

Ana lura da sakamako masu illa na gaba bayan ɗaukar fenofibrates:

• Tsarin narkewa: maganin ciwon huhu, hepatitis, vomiting, ciki na ciki, tashin zuciya, zawo, flatulence, bayyanar gallstones.
• Tsarin Musculoskeletal: rauni na tsoka, rhabdomyolysis, yaduwar myalgia, myositis, rarrafe.
• Tsarin ciki: ciwon kai, lalatawar jima'i.
• Zuciya da jini: embolism na huhu, ƙwayoyin hurawar jini.
• Bayyanar bayyanar cututtuka: itching fata da kurji, daukar hoto, cututtukan mahaifa.

Haɗin gumakan da fibrates ana amfani da su don rage sashi kuma, saboda haka, mummunan bayyanar siffofin.

Magunguna waɗanda ke rage ƙwayar cholesterol na ciki

Magunguna Ezetimibe(Ezetrol) Wani sabon magani ne wanda yake rage yawan narkewar cholesterol a cikin hanji. Bugu da kari, Ezetimibe (Ezetrol) baya tsoratar da ci gaban zawo. Kuna buƙatar shan 10 MG na magani kowace rana. Amma yana da mahimmanci a la'akari da cewa jikin yana samar da kusan 80% na cholesterol, kuma kusan kashi 20% kawai yake cikin abinci.

Duk sauran magunguna

Likitanka na iya ba da shawarar shan kayan abinci (BAA).

Koyaya, magungunan halitta kamar su Omega 3, Harshen Tykveol, man zaren, lipoic acid runtse cholesterol dan kadan.

Ya kamata a ɗauka a cikin zuciya cewa abincin abinci ba magunguna ba ne, saboda haka, irin waɗannan magungunan suna da ƙarancin magungunan statin dangane da rigakafin cututtukan zuciya.

Jerin abincin abinci wanda aka yi amfani da shi don wannan dalili kuma ya ƙunshi abubuwan da suka dace na halitta:

Allunan dauke da kifi mai (Omega 3, Oceanol, Omacor) Ana ba da shawarar don amfani da mutanen da ke neman su rage ƙwayar cholesterol. Kifi na kifi yana kiyaye jiki daga haɓakar cututtukan tasoshin jini da zuciya, kazalika da baƙin ciki da amosanin gabbai. Amma kuna buƙatar shan man kifi a hankali, tunda shan shi yana ƙara haɗarin na kullum cututtukan farji.

An ba da irin ƙwayar Suman ga waɗanda ke wahala cholecystitis, atherosclerosis kwakwalwar kwakwalwa hepatitis. Kayan aiki yana samar da choleretic, anti-inflammatory, antioxidant, sakamako na hepatoprotective.

Cutar Lipoic

Wannan kayan aikin yana da tarko antioxidantAna amfani dashi don yin rigakafi da magani na atherosclerosis na jijiyoyin jini. An lura da sakamako mai kyau na ƙwayoyi akan ƙwayar carbohydrate metabolism.Lokacin da aka ɗauka, trophism na neurons yana inganta, matakan glycogen a cikin hanta suna ƙaruwa.

Bitamin Taimaka wa daidaituwar ƙwayar cholesterol, ƙaruwa hawan jini da sauransu Jiki yana buƙata bitamin b12 da B6, folic acid, Acid na Nicotinic. Yana da mahimmanci cewa waɗannan sune bitamin na halitta, shine, yana da mahimmanci a ci waɗancan abincin da ke ɗauke da waɗannan bitamin.

BAA tsinkayen ƙafafun fir ne, yana ɗauke da beta-sitosterol, polyprenols. Ya kamata a ɗauka lokacin da hauhawar jini, atherosclerosis, babban triglycerides da cholesterol.

Sauran hanyoyin

Masu neman bile acid(Masu keken hannuda dai sauransu) magunguna ne da ake amfani da su a cikin hadaddun magani azaman bangaren taimako don rage haɓakar cholesterol. Suna hana aikinta a cikin plasma.

Ciprofibrate Lipanor - yana hana sinadarin cholesterol a cikin hanta, yana rage matsayinsa cikin jini, yana rage matakin atporogenic lipoproteins.

Don haka, jerin magungunan cholesterol a halin yanzu suna da fadi sosai. Amma idan mai haƙuri yayi ƙarancin rage ƙwayar cholesterol tare da kwayoyi, dole ne ya tuna cewa kwayoyi waɗanda ke rage ƙananan ƙwayar cuta suna haifar da sakamako masu illa. Tabbas, lokacin da ake rubuta magunguna don ƙwayar cutar cholesterol, likita yayi la'akari da wannan, kuma yana sanar da haƙuri game da contraindications don rage ƙwayar cholesterol.

Amma duk da haka, dole ne a dauki magunguna don rage cholesterol na jini, hada irin wannan magani tare da abincikazalika salon rayuwa mai aiki. Yana da kyau a sha magungunan da ke rage cholesterol na jini, sabon zamani, kamar yadda masana'anta ke inganta magunguna.

Kuna iya rage cholesterol jini tare da kwayoyin magunguna zuwa wasu matakan. Amma allunan cholesterol-ƙananan ƙwayoyin cuta yakamata a yi amfani dasu kawai a cikin yanayi inda akwai haɗarin bayyanuwar cutar cututtukan zuciya. Akwai rukuni na marasa lafiya waɗanda suke buƙatar ɗaukar kwayoyin magani don cholesterol a cikin jini. A wasu halaye, kafin ku fara shan kwayoyin don rage cholesterol, ya kamata ku nemi likita wanda ya auna fa'idodi da cutarwa na irin wannan magani.

Don yin cikakken rayuwa, ban da shan kwaya, dole ne ku ci daidai, motsa jiki. Idan cholesterol yana da girma sosai, yana da kyau a canza salon rayuwa nan da nan, wanda zai ba da gudummawa ga al'adarta ba tare da ƙarin magani ba. Hakanan zaka iya aiwatar da shan magungunan mutane, wanda ya haɗa da zuma da sauran abubuwan lafiya mafi kyau waɗanda ke ba ku damar "tsabtace" jiki. Ta yaya kuma sau nawa a rana don cinye irin waɗannan kudade, ƙwararren masani zai gaya.

Yaya za a rage ƙwayar cholesterol?

Don rage cholesterol na jini, da farko, dole ne mai haƙuri ya yi watsi da yawancin samfuran cutarwa. Kula da sautin tasoshin jini na yau da kullun yana da mahimmanci, saboda haka kada mu manta game da fa'idodin wasannin motsa jiki da na waje.

Hanyar da ke ɗauka da ƙwaƙwalwar ƙwaƙwalwa tare da tasirin cholesterol yana da tsayi, kuma mai haƙuri ya kasance a shirye don wannan. A wannan yanayin, yana da mahimmanci ga mara lafiya ya bi duk alƙawura da umarnin likitocin da ke halartar don daidaita yanayin, ba tare da lalata lafiyar kansa ba.

Don haka, don runtse cholesterol jini, dole ne:

• daina mummunan halaye,
• rage cin gishiri,
• cire ko rage yawan abinci mai mai yawa,
• ba da fifiko ga kitse na kayan lambu maimakon dabbobi,
• wadatar da kayan abinci tare da samfuran wadata a cikin fiber na shuka,
• cinye wadataccen carbohydrates,
• Tabbatar ka haɗa da abinci mai wadataccen ƙwayoyin acid a cikin abincinka.

Jerin kayayyakin da aka haramta sun hada da:

• daban-daban sausages (gami da sausages da sausages),
• kuki
• yin burodi
• da wuri
• mirgine.

Hanya madaidaiciya game da batun abinci mai gina jiki tare da cholesterol mai yawa ba kawai zai taimaka wajen "saukar da" abubuwan da ke nuna hakan ba, har ma suna ba da gudummawa ga inganta rayuwar mutum gaba ɗaya.

Yawancin (80%) na cholesterol ana samun su a cikin hanta hanta, kuma 20% kawai ke shiga cikin jiki tare da abinci. Amma menu na daidai da daidaita zai iya ba da gudummawa ga daidaituwa da raguwa mai yawa a cikin tattarawar wannan abu a cikin jini.

Ka'idojin jinyar da ya kamata kowane mai haƙuri ya bishe shi sune:

• rasa nauyi
• wasanni yau da kullun
• Kula da adadin kuzari da aka cinye kowace rana,
• ƙi barasa da sigari,
• guje wa mawuyacin yanayi da damuwa na rashin damuwa.

Don rage mahimmancin wannan abu a cikin jini kuma ya hana ƙirƙirar filayen cholesterol, zaku iya amfani da shirye-shiryen ganyayyaki na musamman da kayan abinci. Don haka, tare da taimakon isasshen ƙwayoyin omega-3 polyunsaturated mai mai yawa, haɗarin thrombosis akan bangon jijiyoyin jini yana raguwa.

A wasu yanayi, gyare-gyaren da aka yi zuwa yanayin rayuwa da jerin abubuwan haƙuri ba sa taimakawa kawar da babban ƙwayar cuta. A wannan yanayin, akwai hanya guda ɗaya kaɗai - don komawa zuwa ga amfani da magunguna na musamman, wanda, duk da haka, likita ne kawai zai iya tsara shi!

Tsara

Don rage taro na cholesterol a cikin jinin mai haƙuri, likitoci sun tsara, a matsayin mai mulkin, shirye-shiryen kwamfutar hannu. An kasu kashi 5:

1. Statins. Wannan rukuni na magungunan likitoci ne ke wajabta shi idan ƙwayar cholesterol ta yi yawa, kuma dole ne a rage shi nan da nan. Wadannan kwayoyi ne masu inganci, ingantattu wanda za'a iya ambata riga 14 kwanaki bayan fara gudanarwa. Ana iya ɗaukar Statins na dogon lokaci.
2. Fibrates. Wannan rukunin magungunan an yi shi ne da nufin yalwata adadin 'cholesterol' mai amfani a jikin mutum. Godiya ga ɗaukar hankalinsu, haɗarin mummunan sakamako akan tsarin na zuciya da jijiyoyi yana raguwa sosai.
3. Abun hanawa. Irin wannan magani baya barin cholesterol ya shiga cikin hanji, amma baya shiga cikin jinin da kanta. Ya fi dacewa ga marasa lafiya waɗanda ke da rashin hankali ga statins.
4. Acid na Nicotinic. Magunguna da ke kan sa suna da tasirin gaske a jikin mai haƙuri: suna cire ƙwayoyin "mummunan" kwayoyi, yayin da suke haɓaka matakin "kyakkyawa", tare da daidaita microcirculation na jini. Kuna iya lura da kuzari mai kyau na farko daga jiyya a cikin 'yan kwanaki.
5. Abincin abinci ana ɗaukar magunguna na duniya gaba ɗaya waɗanda aka yi amfani da su sosai a lokacin yaƙi da ƙwaƙwalwar ƙwayar cuta. Kusan ba su da maganin rikicewar cuta, suna “rushewa” da yawa na “cholest” cholesterol da haɓaka matakin “mai kyau”.

Dukkanin rukuni na sama na kwayoyi daga cholesterol mai girma sun bambanta da juna a cikin abubuwan da ke tattare da su da kuma ka'idar bayyanar jiki. Kowane ɗayan waɗannan rukunin magungunan suna da nasa, ra'ayoyi, da halayen da ba daidai ba waɗanda kuke buƙatar sani game da su.

Yaushe zan buƙaci ɗaukar hotuna?

Duk da tabbacin tallace-tallace da masana'antun ke yi, cikakkiyar amincin irin waɗannan magunguna ga marasa lafiya ba shi da kariya a yau. Idan zamuyi magana game da rabo na amfani da cutarwa na statins, wasu masu binciken sun jaddada cewa hadarin bunkasa sakamako masu illa ya wuce tasirin amfani da su, musamman idan an yi shi don hana cututtukan zuciya idan akwai cutar hypercholesterolemia.

Koyaya, ga wasu nau'ikan marasa lafiya wannan rukunin magungunan ana buƙatar gaggawa. Ana nuna sabbin generationanƙanonin zamani na zamani don amfani da su tare da manufar:

• hana sake dawowa daga bugun zuciya ko bugun jini,
• murmurewa bayan anyi masa tiyata a zuciya ko manyan jijiyoyin jini (ko kuma a cikin shiri),
• hanzarta hanyar warkarwa tare da bugun zuciya ko ciwo na jijiya,

Wadannan magunguna suma suna wajaba ga cututtukan zuciya da ke tattare da hadarin bugun zuciya ko bugun jini.

An ba da shawarar karfi don amfani da statins ga marasa lafiya:

• tare da ƙananan haɗarin rikitarwa na hypercholesterolemia,
• fama da cutar sankara
• mace ba ta hauwa ta menopause.

Lokacin amfani da statins, yana da mahimmanci la'akari da jituwarsu da sauran magunguna.

Mahimmancin Ingancin Cholesterol

Haɓaka cholesterol a cikin ƙwayar jini na iya haifar da cututtuka da yawa. Koyaya, yana da mahimmanci a tuna cewa wannan abu ya kasu kashi mai kyau da mummunan. Kasancewar na farko ya zama dole don sa hannu a cikin mafi mahimman matakai (kirawar hormone, gina membranes a matakin salula).

Bi da bi, abun ciki na mummunan cholesterol a cikin jiki yakan haifar da ci gaban zuciya da cututtukan jijiyoyin jiki. Wannan saboda karancin lipoproteins mai yawa na iya haifar da labulen sclerotic a jikin bangon jijiyoyin jiki.

Don kawar da wannan mummunan yanayin, a mafi yawan lokuta, an tsara magungunan anticholesterol.

Abubuwan da ake buƙata don shan magani

Wasu bayyanar cututtuka na iya nuna karuwa a cikin alamar cholesterol:

• angina pectoris
• bugun zuciya
• gajiya da zafi a cikin ƙananan ƙarshen lokacin wasanni masu zafi,
• rawaya inuwa a kusa da idanu,
• katse jini.

Idan kuna zargin cutar sankara, dole ne a tuntuɓi cibiyar likita don gwajin jini na ƙwayoyin cuta. Idan sakamakon ya nuna kyawawan dabi'u, likita zai ba da umarnin da ya dace.

Ana amfani da magungunan cholesterol idan wasu hanyoyin ba su bayar da sakamako mai amfani ba.

Bugu da kari, abubuwan da ake bukata domin maganin magunguna sune:

• cututtukan zuciya da na zuciya, wanda ke kara hadarin kamuwa da ciwon zuciya,
• dabi'ar gado
• tarihin bugun jini ko bugun zuciya,
• na jijiyoyin zuciya jijiya cuta.

Ba za ku iya rage cholesterol tare da magunguna ba a cikin halaye masu zuwa:

• babu wata barazana ga rayuwa da lafiyar mai haƙuri dangane da asalin bugun jini ko bugun zuciya,
• Mace ba ta kai lokacin haila ba,
• tarihin ciwon sukari mellitus.

Ko da kuwa da alamun, ba za ku iya ɗaukar maganin ba da kanku. Don ba da magani, dole ne a nemi likita.

Shirye-shiryen Nicotinic Acid

Allunan acid na Nicotinic acid suna rage maida hankali kan karancin abinci mai yawa ta hanyar hana hako su. Amsar tambayar yadda ake aiwatar da wannan tsari har zuwa yau ba a karɓa ba.

A halin yanzu, masana sun tabbatar da cewa idan kun dauki miyagun ƙwayoyi a adadi mai yawa, zaku iya rage haɗarin atherosclerosis.

Daga cikin munanan halayen sune:

• zazzabi da mai haƙuri yake ji a cikin sashin jiki na fuska da fuska,
• bayyanar rashin lafiyan halayen,
• ƙara darajar glucose a cikin marasa lafiya da ciwon sukari mellitus,
• take hakkin tsarin narkewa.

A wannan batun, yawan nicotinic acid ya kamata ya fara da karamin kashi tare da karuwa a hankali. A lokacin duk lokacin jiyya tare da wannan magani, mai haƙuri ya kamata ya kasance ƙarƙashin kulawar likita.

Contraindications sun hada da:

• na ciki da na ciki,
• na kullum hepatitis
• gout
• cututtukan zuciya (ana iya lura da raguwa ko karuwa a bugun bugun zuciya).

Ofayan mafi ingantattun wakilai waɗanda ke ɗauke da wannan abun shine Enduracin.

Masu neman bile acid

Magunguna na wannan rukunin suna rage cholesterol a sakamakon haɗuwa da ƙwayoyin bile da kuma canza su cikin abubuwan da basa narkewa a ruwa. Koyaya, jikin ɗan adam ba zai iya yin ba tare da su ba kuma yana karɓar abu ta hanyar haɓakar cholesterol. A sakamakon irin waɗannan hanyoyin, yawan adadin ƙwayoyin cututtukan jijiyoyin jini a cikin abun da ke cikin jini ya ragu.

• babu sakamako
• babu wani sakamako na tsari.

• sakamakon tabbatacce zai zama sananne ne kawai bayan 'yan makonni tare da amfani da magani na yau da kullun,
• babu wani ci gaba a cikin tsarin jijiyoyin bugun gini,
• aiwatar da jikewa tare da bitamin da abubuwa masu mahimmanci sun tarwatse.

Ana ɗaukar masu neman zaɓe cikin ƙarancin allurai, dole ne a wanke su da ruwa mai yawa. A kan wannan yanayin, narkewar tsarin abinci na iya faruwa, wanda ke haɗuwa da tashin zuciya, maƙarƙashiya ko zawo, amai.

Daga cikin mafi kyawun kayan aiki a wannan rukunin:

1. Cholestyramine. Wannan shiri ne mai inganci daga wanda aka shirya dakatarwar. Guda abu ɗaya a cikin abun da ke ciki yana taimakawa rage yawan kitse mai kitse da sinadarin cholesterol, haka kuma yana haɓaka samar da sinadarin bile a cikin hanta, wanda hakan ya sa cholesterol mai cutarwa ya fara cinyewa.
2. Cholestipol. Ya ƙunshi resin musayar anion, wanda ke cikin aiwatar da haɗuwa da bile acid da canjinsu zuwa cikin mahadi waɗanda ba mai narkewa cikin ruwa ba. Ayyukan miyagun ƙwayoyi yana rage adadin ƙwayar cuta mai haɗari, yayin riƙe da HDL mai mahimmanci (babban adadin lipoproteins mai yawa).

Tunda kudaden wannan rukunin sun banbanta da tasirin yankuna, basa bada tasirin mummunar dabi'a ta tsari. Don hana aiwatar da cututtukan cututtukan kwayoyin cuta a cikin gabobin narkewa, haɓaka kashi ya kamata ya faru a jinkirin saurin zuwa inda ake so.

Bugu da kari, yana da mahimmanci a lura cewa masu bin diddigin zasu iya lalata shakar wasu magunguna. A wannan batun, ana ɗaukar sa'o'i huɗu kafin ko sa'a ɗaya bayan amfani da wata hanyar.

Wannan rukuni ne daban na magungunan da ke daidaita darajar cholesterol, tare da daidaita haɓakar metabolism da ƙirar ƙwayoyin dabbobi a jikin mutum.

Mafi yawan magunguna da aka tsara daga jerin magungunan da ke ƙasa:

1. Bezafibrat. Allunan ba kawai taimakawa rage yawan kitse na lipid ba, amma kuma inganta yanayin janar na marasa lafiya da ke fama da cutar angina pectoris da ischemia. Sunayen irin wadannan kudade: Oralipin, Benzamidine, Zedur. Tsawon lokacin jiyya shine kwanaki 30. Bayan haka, hutu na wata daya
2. Gemfibrozil. A lowers triglycerides, low mai yawa da kuma taimaka hanzarta cholesterol excretion. Ana iya ganin tasirin bayan kwana 30 na kwaya. Tun da abu ya zauna cikin ruwan jini na dogon lokaci, an ba shi izinin ɗaukar ƙananan tazara a cikin jiyya, za a sami sakamako mai warkewa.
3. Wannan shi ne fibrate. Aikinta yana rage dankowar jini da jini. A mafi yawan lokuta, kantin sayar da magunguna suna sayar da magani tare da irin wannan sakamako, wanda ake kira Lipo-Merz. Ana shan miyagun ƙwayoyi sau ɗaya a rana bayan cin abinci.

Fibrates suna contraindicated a:

• dauke da yaro da shayarwa,
• cholecystitis
• gazawar hanta da cirrhosis,
• rashin ƙarfi ga abubuwan da aka gyara,
• na kullum na koda.

Daga cikin sakamako masu illa ana lura da su:

• anemia
• ciwon kai
• rashin lafiyan mutum
• cuta narkewa,
• nutsuwa
• tsananin farin ciki
• leukopenia
• alopecia.

Yana da kyau a lura cewa mummunan sakamako ƙarancin abu ne.

Waɗannan sune shahararrun allunan cholesterol na duk ƙungiyoyi.

Daga cikin samfuran farko na farko sune:

Suna da tasirin gaske game da samar da cholesterol mai amfani kuma ana wajabta su idan akwai babban matakin LDL. Kyakkyawan magani ana daukar su simvastatin. Idan ka dauke shi na dogon lokaci, kaudawar spasms na tasoshin jini da rage karfin jini.

Statins 2 zamaninsu:

An wajabta su a cikin matsanancin halayen saboda haɗarin haɗarin sakamako masu illa.

Na ƙarni na kwayoyi:

• Thorvacard
• Kaya Yanar,
• Tulip

Suna da ƙaramin jerin mummunan aiki. Atorvastatin yana halartar zuciyar kowane magani.

Sabbin magunguna:

Waɗannan ƙarin magunguna ne na zamani waɗanda ake amfani da su don daidaita tasirin cholesterol a cikin jini. Siffar su shine tsaro, ƙarancin haɗarin mummunan sakamako.

Marasa lafiya ya kamata su tuna cewa haramun ne a dauki mutum-mutun a kashin kansa. Ana gudanar da alƙawarin ne ta hanyar kwararrun Likita. Idan ka yi watsi da magungunan likitan, to, yiwuwar wasu tasirin sakamako yana ƙaruwa, wanda ke tare da:

• tashin zuciya da amai
• ciwon kai, tsananin farin ciki,
• zuciya rudani,
• ƙarancin ciki, maƙarƙashiya ko zawo,
• tsoka da ciwon gwiwa
• kumburi, rashin lafiyan jiki, itching,
• ƙarancin koda da aikin hanta.

Yardajewa:

• predisposition zuwa rashin lafiyan dauki,
• rashin haƙuri da aka gyara
• hanta da cututtukan koda,
• lokacin ciki da shayarwa,
• hargitsi a cikin tsarin endocrine.

A matsayinka na mulkin, mutum-mutumi na hudu ya ba da sakamako mai sauri, wanda za'a iya gani riga a farkon watan amfani.

Kwayoyin cutar cholesterol: lokacin da aka wajabta, sakamako masu illa

HMG-CoA reductase inhibitors, a cikin wasu kalmomin, statins, sune babban rukuni na magungunan da aka tsara don manyan ƙwayar cholesterol, waɗanda basu da alamun analogues. Idan adadin cutar LDL mai cutarwa ya fi ƙarfin al'ada da kuma daidaita abinci mai gina jiki bai taimaka wajen gyara lamarin ba, an wajabta mai haƙuri a matsayin magani na tsawon lokaci.

Ka'idar aikinsu ita ce dakatar da aikin enzyme wanda ke da alhakin samar da sinadarin cholesterol a cikin hanta, da kuma rage haɓakar atherosclerosis. Magungunan kwayoyin cuta na yau da kullun suna taimakawa tsawon lokaci ga mutanen da ke fama da cutar atherosclerosis, raunin jiki, wadanda suka kamu da cututtukan zuciya.

Yaushe kuma wanene yake buƙatar ɗaukar mutummutumai

An wajabta ƙwayoyin cholesterol don mutanen da ke da haɗarin kamuwa da bugun zuciya da bugun jini, lokacin da ƙwayar cholesterol ta tabbata, baya raguwa, kuma shine 300-330 mg / dl ko 8-11 mmol / l, haka kuma a lokuta inda aƙalla yanayi guda ya cika:

• bugun zuciya, bugun jini ko bugun zuciya,
• na jijiya marasa lafiya kewaye da grafting,
• Zazzabin zafin jiki na cututtukan jijiyoyin zuciya,
• Tsarin gina jiki mai dauke da sinadarin (c-reactive) da kuma ajiyar alli a cikin hanyoyin.

Ba a ba da magani tare da kwayoyin hana daukar ciki cholesterol don mutanen da ke da ƙoshin lafiya tare da ƙara ƙarancin matakan LDL, tunda mummunan tasiri akan jikin zai kasance mai ƙarfi fiye da fa'idodi. Hakanan ba a ba da shawarar fara magani tare da statins ba a cikin waɗannan lambobin:

• ƙarami da rashin daidaituwa game da ƙwayoyin cuta,
• rashin atherosclerosis,
• babu bugun zuciya ko bugun jini
• babu wani abun ajiyar alli a cikin majigaba ko kuma bashi da mahimmanci,
• c-mai amsawa mai ƙarancin abu ƙasa da 1 mg / dl.

Ya kamata a ɗauka a zuciya cewa jiyya tare da statins na iya ci gaba cikin rayuwa. Lokacin da aka soke su, matakin cholesterol zai koma matakan da ya gabata.

Yin amfani da statins ya kamata a aiwatar dashi kawai akan shawarar likita saboda yawancin contraindications da sakamako masu illa. Lokacin rubuta allunan, ana la'akari da abubuwan da ke ƙasa:

• shekaru da jinsi na haƙuri
• tsoffin cututtukan da suka gabata ko na yanzu na tsarin zuciya da jijiyoyin jini, gami da ciwon suga.

Ya kamata tsofaffi marasa lafiya su ɗauki mutum-mutumi tare da matsanancin hankali idan suna amfani da wasu magunguna waɗanda aka tsara don kula da hauhawar jini, gout, ko ciwon sukari. Don wannan rukuni na marasa lafiya, ana yin gwajin jini da gwajin hanta sau 2 sau da yawa.

Cutar sankarau da jikin mutum-mutumi

Statins suna da wasu mahimmin haɓaka - suna haɓaka sukari na jini da 1-2 mmol / L. Wannan yana ƙara haɗarin nau'in ciwon sukari na II daga 10%. Kuma a cikin wadancan marasa lafiya da suka kamu da cutar sankara, suna daukar kwayar cutar statins suna hana mutum yaduwar saurin saurin ci gaba.

Amma, ya kamata a fahimci cewa fa'idodin ɗaukar mutum-mutumi na iya zama mafi girman tasirin da suke samu a jiki. Magunguna suna iya rage haɗarin bugun zuciya da bugun jini, da tsawaita rayuwa, wanda ya fi muhimmanci sama da ƙara yawan jini a cikin jini.

Tare da ciwon sukari, yana da matukar muhimmanci cewa jiyya ta kasance cikakke. Shan allunan yakamata a hade dasu tare da karancin carbon-abinci, kara karfin jiki da kuma yawan insulin.

Genididdigar halittu na mutum-mutumi, farashin matsakaici a cikin magunguna

Abin da magunguna ke da alaƙa da statins da kuma yadda suke tasiri ga rage ƙwayar cholesterol za'a iya samu a teburin.

Magunguna waɗanda ke lalata ƙwayar cholesterol na hanji

Ta hanyar rage yawan shan sinadarin cholesterol daga abinci a cikin hanjin, wadannan kwayoyi suna rage maida hankali a cikin jini.
Mafi ingancin wannan rukunin kudaden shine guar. Wannan kari ne na ganyayyaki wanda aka samo daga zuriyayen wake na hyacinth. Ya ƙunshi polysaccharide mai ruwa-ruwa, wanda ke samar da jelly yayin hulɗa da ruwa a cikin lumen hanji.

Guarem da kankare ya cire kwayar cholesterol daga bangon hanji. Yana haɓaka kawar da acid bile, wanda ke haifar da karɓar ƙwayar cholesterol daga jini zuwa cikin hanta don haɗinsu. Magungunan yana hana abinci ci da rage yawan abincin da ake ci, wanda hakan ke haifar da asarar nauyi da kuma yawan kiba a cikin jini.
Ana samar da guarem a cikin kayan ado, wanda yakamata a ƙara shi cikin ruwa (ruwa, ruwan 'ya'yan itace, madara). Shan miyagun ƙwayoyi ya kamata a haɗe shi da sauran magungunan antiatherosclerotic.

Abubuwan da ke haifar da sakamako sun haɗa da bloating, tashin zuciya, jin zafi a cikin hanji, da kuma wasu lokatai kwance. Koyaya, ana ɗan bayyana su, da wuya ake faruwa, tare da ci gaba da aikin likita ba tare da izini ba.

Acid na Nicotinic

Acidicic acid da abubuwansa (enduracin, niceritrol, acipimox) shine sinadarin bitamin rukuni na B. Yana rage taro da "mummunan cholesterol" a cikin jini. Nikotinic acid yana kunna tsarin fibrinolysis, yana rage karfin jini don samar da ƙwanƙwasa jini. Wannan magani yana da inganci fiye da sauran magunguna masu rage ƙwayar ƙwayar lipid wanda ke ƙara haɗuwa da "kyakkyawan cholesterol" a cikin jini.

Ana gudanar da aikin maganin Nicotinic acid na dogon lokaci, tare da karuwa a hankali a kashi.Kafin kuma bayan shan shi, ba a bada shawara a sha giya mai zafi, musamman kofi.

Wannan magani na iya haushi da ciki, saboda haka ba a sanya shi don maganin cututtukan ciki da cututtukan peptic. A cikin marasa lafiya da yawa, jan fuska ya bayyana a farkon jiyya. A hankali, wannan tasiri ya ɓace. Don hana shi, an ba da shawarar a ɗauki 325 mg na asfirin minti 30 kafin a sha maganin. 20% na marasa lafiya suna da fatar fata.

Jiyya tare da shirye-shiryen nicotinic acid an contraindicated a cikin lokuta na ciwon ciki da kuma duodenal miki, hepatitis na kullum, tsananin bugun zuciya, da gout.

Enduracin magani ne nicotinic acid. Ya fi dacewa da haƙuri, yana haifar da mafi ƙarancin sakamako. Ana iya bi da su na dogon lokaci.

Magungunan suna da kyau rage matakan “kyau” da kuma “mummunan” cholesterol. Magungunan ba ya shafar matakin triglycerides.

Magungunan yana cire LDL daga jini, yana haɓaka fitowar cholesterol tare da bile. Yana hana liroxidation na lipid, yana nuna sakamako na antiatherosclerotic.

Tasirin maganin yana bayyana watanni biyu bayan fara magani kuma ya kasance har zuwa watanni shida bayan an dakatar dashi. Ana iya haɗe shi tare da kowane sauran hanyoyin da ke rage ƙwayar cholesterol.

A ƙarƙashin tasirin miyagun ƙwayoyi, tsawaita tazara ta Ts-T akan ƙwayar lantarki da haɓakar rikicewar ventricular rhythm damuwa mai yiwuwa. A lokacin gudanarwarsa, ya zama dole a maimaita tsarin wutan lantarki a kalla sau daya a kowane watanni 3 zuwa 6. Ba za ku iya sanya probucol lokaci guda tare da cordarone ba. Sauran illolin da ba a ke so sun hada da nazuciya da na ciki, tashin zuciya, da wasu lokutan kwance kwance.

Probucol yana cikin kwanciyar hankali a cikin ventricular arrhythmias wanda ke da alaƙa da tazara ta Q-T, lokuttan maimaitawa na ischemia myocardial, kuma tare da matakin ƙara girman matakin farko na HDL.

Fibrates yadda yakamata su rage matakin triglycerides a cikin jini, zuwa kasalar da yawaitar yawan abubuwan LDL cholesterol da VLDL. Ana amfani dasu a cikin lokuta na babban hypertriglyceridemia. Kayan aikin da aka saba amfani dasu sune:

• gemfibrozil (m, gevilon),
• fenofibrate (lipantil 200 M, treicor, tsohuwar lipip),
• cyprofibrate (lipanor),
• choline fenofibrate (trilipix).

Abubuwan da ke haifar da sakamako sun haɗa da lalacewar tsoka (zafi, rauni), tashin zuciya da raunin ciki, rashin aikin hanta mai rauni. Fibrates na iya haɓaka samuwar calculi (duwatsu) a ciki mafitsara. A cikin lokuta masu wuya, a ƙarƙashin rinjayar waɗannan wakilai, hanawar hematopoiesis yana faruwa tare da haɓakar leukopenia, thrombocytopenia, anemia.

Fibrates ba a wajabta su ba don cututtukan hanta da ƙwayar hanta, hematopoiesis.

Statins su ne mafi inganci magungunan rage kiba. Sun toshe enzyme da ke da alhakin sinadarin cholesterol a cikin hanta, yayin da abun cikin shi ke raguwa. A lokaci guda, adadin masu karɓar LDL yana ƙaruwa, wanda ke haifar da haɓakar haɓakar "mummunan cholesterol" daga jini.
Magungunan da akafi amfani dasu sune:

• simvastatin (vasilip, zokor, aries, simvageksal, simvakard, simvakol, simvastin, simvastol, simvo, simlo, sincard, holvasim),
• lovastatin (cardiostatin, choletar),
• pravastatin
• atorvastatin (anvistat, atocor, atomax, ator, atorvox, atoris, vazator, lipoford, lypimar, liptonorm, novostat, torvazin, torvakard, tulip),
• rosuvastatin (akorta, giciye, mertenil, rosart, rosistark, rosucard, rosulip, roxera, rustor, tevastor),
• pitavastatin (livazo),
• fluvastatin (leskol).

Lovastatin da simvastatin an yi su ne daga fungi. Waɗannan sune “prodrugs,” waɗanda a cikin hanta suka juya zuwa matakan metabolites masu aiki. Pravastatin asalinsa ne na metabolites na fungal, amma ba a metabolized a cikin hanta ba, amma ya riga ya zama abu mai aiki. Fluvastatin da atorvastatin sune kwayoyi masu haɓaka.

Ana wajabta Statins sau daya a rana da maraice, saboda ganuwar cholesterol a jiki yana faruwa da dare.A hankali, maganin su na iya ƙaruwa. Sakamakon ya faru riga a cikin kwanakin farko na gudanarwa, ya kai mafi girma a cikin wata daya.

Statins basu da lafiya. Koyaya, lokacin amfani da manyan allurai, musamman a hade tare da fibrates, aikin hanta mai rauni yana yiwuwa. Wasu marasa lafiya suna jin zafin ƙwayar tsoka da rauni. Wani lokacin akwai ciwon ciki, tashin zuciya, maƙarƙashiya, rashin ci. A wasu halaye, rashin bacci da ciwon kai wataƙila.

Statins ba su shafi aikin purine da carbohydrate metabolism. Ana iya tsara su don gout, ciwon sukari, kiba.

Statins wani bangare ne na ka'idoji don lura da atherosclerosis. An tsara su azaman maganin monotherapy ko a hade tare da sauran jami'in antiatherosclerotic. Akwai haɗin da aka shirya don lovastatin da nicotinic acid, simvastatin da ezetimibe (ingee), pravastatin da fenofibrate, rosuvastatin da ezetimibe.
Ana haɗuwa da haɗuwa da statins da acetylsalicylic acid, da atorvastatin da amlodipine (duplexor, caduet). Amfani da haɗakar riga da aka shirya yana ƙaruwa da haƙuri ga haƙuri (yarda), yana da fa'ida ga tattalin arziƙi, kuma yana haifar da raguwar sakamako.

Sauran magunguna masu rage kiba

Benzaflavin yana cikin rukunin bitamin B2. Yana inganta metabolism a cikin hanta, yana haifar da raguwa a cikin matakan jini na glucose, triglycerides, total cholesterol. An yarda da maganin sosai, an tsara shi a cikin darussan dogon.

Mahimmanci ya ƙunshi mahimmancin phospholipids, bitamin B, bitamin nicotinamide, acid mai narkewa, sodium pantothenate. Magungunan yana inganta fashewa da kawar da "mummunan" cholesterol, yana kunna kyawawan kaddarorin "cholesterol" mai kyau.

Lipostable yana gab da kasancewa da aiki don Muhimmiyar.

Omega-3 triglycerides (omacor) an wajabta su don magance cututtukan cututtukan jini (ban da nau'in hyperchilomicronemia na 1), kazalika don rigakafin yaduwar cutar sankara.

Ezetimibe (ezetrol) yana jinkirta shan ƙwayar cholesterol a cikin hanji, yana rage yawan ci a cikin hanta. Yana rage abun cikin "mara kyau" cholesterol a cikin jini. Magungunan sun fi tasiri a hade tare da statins.

Bidiyo akan taken "Cholesterol da statins: Shin ya cancanci shan maganin?"

Adana Haraji zuwa Tsofaffi

Lokacin nazarin sakamakon wannan rukuni na kwayoyi a jikin marasa lafiya fiye da shekaru 60, an lura da ciwon tsoka a cikin 30% na lokuta. Marasa lafiya suna koka game da gajiya, sanyin jiki da rage sautin tsoka. Jin zafi a cikin kasusuwa kasusuwa ya faru a cikin mafi yawan marasa lafiya waɗanda suka fara shan magani.

Dangane da abubuwan da aka gabata, a cikin yawancin mutanen da ke fama da hypercholesterolemia, akwai raguwa a cikin aikin tunani da ta jiki ta minti 40 a mako. Sakamakon rauni na tsoka, marasa lafiya sun rasa sha'awar wasa wasanni, har ma da tafiya na yau da kullun. Wannan, a hankali, na kara hadarin kamuwa da bugun zuciya da bugun jini.

Statins - Jerin Magunguna

A cikin kantin magunguna na Rasha, zaku iya siyan sifoffin masu aiki masu matukar tasiri don rage cholesterol:

1. Rosuvastatin, wanda yake rage kwayar cholesterol da kashi 55%.
2. Atorvastatin, wanda ya rage matakin da kashi 47%.
3. Simvastatin (38%).
4. Fluvastatin (29%) da sauransu.

Ana iya duba cikakkun jerin magungunan cholesterol a ƙasa:

Shin ya cancanci ɗaukar gumaka ko yana da kyau a bar su - wannan ya kamata mai yanke shawara ya yanke shawara, bisa shawarar likitocin da ke halartar. Idan mai haƙuri, duk da haka, ya yanke shawara a kan irin wannan ilimin, to bai kamata ku zaɓi ƙwayar da kanku ba - wannan ya kamata a yi shi na musamman ta hanyar ƙwararrun masani, yin la'akari da duk haɗarin da zai yiwu da kuma kasancewar cututtukan cututtukan ƙwayar cuta a cikin mutum.

Fibrate Magunguna

Fibrates - kwayoyi waɗanda ke haifar da fibroic acid. Kamar statins, ana cin nasarar amfani dasu don yaƙar ƙwayoyin cholesterol.Saduwa da bile acid, waɗannan abubuwa suna hana aiwatar da kwayar cholesterol ta hanta.

Fenofibrates yana taimaka wa ƙananan lipids a cikin jiki, wanda ke haifar da raguwa a cikin yawan ƙwayar cholesterol. Tare da ciprofibrates, suna rage haɗarin haɓaka rikice rikicewar ƙwayar cuta na hypercholesterolemia, tunda sun daidaita ba kawai cholesterol ba, har ma triglycerides.

Mafi inganci kuma sanannun fenofibrates sun hada da kwayoyi:

• Gemfibrozil
• Taykolor,
• Lipantil
• Fitowa 200 da sauransu.

Amma yanke shawarar siyan wani samfurin ya zama dole idan an ƙaddara rabo na fa'idodi / ƙoshin lafiya. Irin waɗannan kwayoyi na iya haifar da sakamako masu illa, waɗanda suka fi yawa daga cikinsu sun haɗa da:

• binnewa
• ƙwannafi
• bloating, tare da ƙarancin wuta,
• zawo
• amai
• tashin zuciya
• ci gaban hepatitis
• samuwar kashin a cikin gallbladder ko gorin sa,
• yadawo myalgia,
• jijiyar wuya
• cephalgia
• rikice-rikice a cikin aikin yanki,
• rashin lafiyar hanji
• thrombophlebitis
• fata tayi
• rashin lafiyar urticaria
• ƙaiƙayi jiki
• daukar hoto.

Don rage mummunan tasirin statins akan jiki, ana iya amfani dasu kuma yakamata ayi amfani dasu a hade tare da fibrates.

Abubuwan hana Cholesterol

Ezetemib (Ezeterol) sabon magani ne da ke rage lodin abinci a jiki. A sakamakon wannan, ana hana aiwatar da sinadarin cholesterol a cikin hanji.

Bugu da kari, Ezetemib, sabanin Orsoten da sauran magunguna masu kama da haka, da wuya ya haifar da ci gaban zawo. Matsakaicin izinin maganin yau da kullun shine 10 g.

Bayan haɓakar cholesterol, ƙwayoyin ƙwayoyin niacins suna ba da gudummawa ga:

• haɓaka wurare dabam dabam na jini,
• Tsarin tsari na rayuwa,
• hana ci gaban rashi na bitamin,
• cire gubobi daga jiki.

Ana iya amfani da wannan rukunin magungunan biyu daban-daban kuma a zaman wani ɓangare na rikicewar jiyya. Zai fi kyau a yi amfani da acid nicotinic acid ko abubuwan da aka samo shi da sinadarin cholesterol.

Sauran magunguna

Bayan shawarwari na farko tare da likita, mai haƙuri na iya ƙoƙarin rage ƙananan ƙwayoyin cuta ta amfani da kayan abinci.

Jerin abubuwan da ake amfani da shi na kayan abinci wanda za a iya amfani dasu don manyan cholesterol:

1. Shirye-shirye wanda ya ƙunshi Omega-3 (mai kifi, Omega-3, Oceanol, da dai sauransu) yana hana cututtukan zuciya da jijiyoyin jini, ƙarfafa gidajen abinci da rage haɗarin rashin kwanciyar hankali. Irin waɗannan magunguna ya kamata a ɗauka tare da taka tsantsan, tunda suna ƙara haɗarin haɓakar ƙwayar ƙwayar cuta na kullum.
2. Lipoic acid yana da tasiri mai kyau a cikin metabolism metabolism. Amfani da shi yana taimakawa haɓaka ƙoshin ƙwayoyin trophic da haɓaka matakin hepatic glycogens.
3. Tykveol magani ne wanda ya danganta da irin kabewa. Yana da amfani musamman ga cerebral arteriosclerosis, cholecystitis, hepatitis. A miyagun ƙwayoyi yana da choleretic, anti-mai kumburi, antioxidant da hepatoprotective illa.
4. Abubuwan Vitamin. Vitamin na rukuni na B ya zama dole musamman ga cholesterol mai girma: B6, B9, B12 da nicotinic acid. Wannan ba wai kawai game da shirye-shiryen magunguna bane - don don daidaita tsarin ƙwayar lipid, kuna buƙatar amfani da samfuran da ke ɗauke da abubuwan da ke sama.
5. Polyconazole Supplementarin karin abinci ne wanda ya ƙunshi cire kayan kakin zuma. Yana taimakawa hana atherosclerosis na jijiyoyin jini da ƙananan cholesterol mai ƙarancin jini.

Kammalawa

Magungunan da ke rage ƙwayar cholesterol suna da rashi mai yawa, tunda zasu iya haifar da sakamako masu illa da yawa. Don wannan, ra'ayoyin likitocin game da amfani da su sun sha bamban.

Haka kuma, ba statins ko wasu magunguna ba da shawarar ga marasa lafiya yan ƙasa da shekara 35.Tunda mata basa iya fuskantar cutar sikila, sun fi kyau su guji shan kwayoyi masu rage cutar kwayoyi. Don kawar da matsalar da ke akwai, ya wajaba a yi wasu canje-canje ga abincin kuma a canza salon rayuwa.

Amma akwai lokuta yayin shan kwayoyin yana da matukar mahimmanci don daidaita yanayin haƙuri. A irin wannan yanayi, ƙwararren likita na iya tsara shi ta musamman!

Toari ga aikin magani, yana da muhimmanci a kawar da munanan halaye tare da yin motsa jiki. Kawai sai a samu damar murmurewa zai karu sosai!

Fibrates - Kalam na Fibroic Acid

Fibrates sune magunguna na biyu mafi inganci don taimakawa magance manyan cholesterol. Mafi yawancin lokuta ana amfani dasu a hade tare da statins. A cikin wasu halaye, ana tsara su azaman kuɗi masu zaman kansu.

Hanyar aiwatar da allunan shine inganta ayyukan lipoproteinplase, wanda ke rushe barbashi mai ƙarancin ƙarfi. A lokacin jiyya, ana kara hanzarin metabolism, matakin ingantaccen cholesterol ya hau, metabolism metabolism a cikin hanta ya zama al'ada, kuma hadarin atherosclerotic plaques da cardiac pathologies yana raguwa.

Magungunan ƙwayar cuta ta Fibrate suna da kyau haƙuri ta haƙuri. Abubuwan da ke haifar da sakamako masu illa suna faruwa a cikin lokuta mafi wuya (kusan 7-10%).

Mafi ingancin magunguna sune:

• Clofibrate. Yana da rawar jiki da ake magana a jiki, yana haɓaka tafiyar matakai a cikin hanta, yana rage ƙyamar jini da kuma jijiyoyin jini. Ba a ba da izinin rigakafin gado ko gado hypercholesterolemia ba.
• Gemfibrozil. Kalafan Clofibrate ba tare da yawan guba da cutarwa ba. Tana faɗin kaddarorin rage kiɗa. Yana rage LDL, VLDL da triglycerides, yana ƙaruwa da HDL, yana haɓaka kawar da ƙwayoyin mai mai kyauta daga hanta.
• Bezafibrat. Wersaukar cholesterol da glucose, yana rage haɗarin thrombosis. Ya faɗi ƙimar antiatherosclerotic.
• Fenofibrate. Magungunan zamani mafi inganci don ingancin cholesterol daga rukunin fibrates. Ana ɗauka magani ne na gama gari a cikin yaƙi da ƙarancin ƙwayar cuta mai narkewa da haɓakar insulin. Baya ga kaddarorin rage yawan lipid, yana da anti-mai kumburi, antioxidant da tasirin tonic.

Fibrates an haramta shi sosai ga mutanen da ke fama da cholelithiasis, gall mafitsara, hanta da ƙonewar koda. Tare da kulawa sosai, an wajabta su ga samari da tsofaffi.

Abubuwan sunadarin Nicotinic acid

Niacin (Niacin, Vitamin PP, B₃) - wani magani ne da ke cikin ƙwayar tsoka, haɗarin enzyme, halayen sake juyawa.

Tare da babban cholesterol, an sanya Niacin a hade tare da wasu kwayoyi don inganta kayan jini, fadada ƙwayar jijiyoyin bugun jini da kuma daidaita yanayin jini. Niacin kuma yana hana halayen kumburi, dilates kuma yana karfafa hanyoyin jini, yana da tasirin gaske a jiki.

Ana aiwatar da ilimin a ƙarƙashin tsananin kulawa na likita. M halayen masu yiwuwa ne - rashin lafiyan, jin zafin zafi, rashin aiki na kayan narkewa, haɓaka glucose (haɗari ga marasa lafiya da ciwon sukari mellitus).

Cholesterol sha inhibitors

Magunguna na wannan rukuni ba su ƙyalƙyashe sinadarin bile kuma ba sa hana samar da cholesterol ta hanta. Ayyukansu suna da niyyar rage kwararar acid daga cikin karamin hanji zuwa hanta. Saboda wannan, an rage ajiyar kayan, kuma inganta haɓakawa daga cikin jini ya inganta.

Mafi ingancin magunguna a cikin wannan rukuni:

• Ezetimibe (analogues: Ezetrol, Lipobon). Kwayoyin sabon aji. Rage sha daga cholesterol a cikin karamin hanji. Kada ku rage haɗarin bugun zuciya da bugun jini, kada ku shafi ɗaukacin rayuwar mai haƙuri. Mafi inganci lokacin da aka haɗa su tare da statins. Tasirin sakamako yana yiwuwa - rashin lafiyan, gudawa, lalata abubuwa da ke cikin jini.
• Guarem (guar gum). Yana da hypocholesterolemic da tasirin hypoglycemic. Yana rage yawan tasirin cholesterol a cikin karamin hanji, yayin da yake inganta hanyoyin metabolism a hanta. Tare da ƙwaƙƙwarar magani, yana rage matakin LDL da triglycerides da 10-15%.

Magunguna don rage ƙwayar jini cholesterol an wajabta su don na farko da na gado na hypercholesterolemia, tare da rikicewar ƙwayar lipid a gaban ciwon sukari mellitus.

Shirye-shiryen ganye

Yin amfani da wannan rukunin magungunan yana halatta kawai tare da excessarancin adadin mai nuna alama ko kuma ƙari ga babban jiyya.

Samfuran da ke gaba suna da kyakkyawan tasirin anticholesterol:

• tashi hip
• rasberi
• chokeberry,
• kumbura,
• hawthorn
• seleri, tafarnuwa da karas suna taimakawa wajen tsarkake hanyoyin jini,
• yarrow, Linden, motherwort, hatsi suna inganta aikin hanta da ƙananan ƙwaro.

Tushen Dandelion yana taimakawa wajen daidaita tsarin narkewa, wadatar da jiki tare da abubuwan da ake buƙata, da kuma hana ɗaukar cholesterol daga abinci.

Daga cikin abubuwan abinci, masu shahara sunfi shahara:

A matsayin madadin, sanya:

1. Aterol. Yana da aiki wanda ke taimakawa tsaftace jini da hanta, sannan kuma yana sarrafa nauyin mai haƙuri. An yi shi a cikin nau'i na capsules. Kari akan haka, kayan aiki na daidaita ayyukan narkewa, da nufin rarrabu abubuwa masu cutarwa da cire su daga jikin mutum.
2. Choledol Yana haɓaka metabolism, rage ƙwaƙwalwar ƙwayar jini, dawo da hawan jini. Magungunan ba ya ba da sakamako masu illa kuma yana ba da gudummawa ga saurin haɓaka kyautatawa.

Alfalfa Anticholesterol da Ateroclefit suna daidai da mashahuri. A peculiarity na saponins ba a cikin alfalfa ne hadaddun warkewa sakamako.

Ba wai kawai suna hana samuwar mummunan cholesterol ba, harma suna hana atherosclerosis na jijiyoyin bugun jini, suna kara karfin garkuwar jiki, kuma suna da tasirin antitumor.

Magunguna waɗanda ke haɓaka haɓakar bangon jijiyoyin bugun jini

Ana amfani dasu don haɓaka inganci da tasiri na babban magani da rigakafin rikice-rikice na atherosclerosis. Karin taimako ya hada da magungunan da ke inganta kaddarorin jini, yanayin bangon jijiyoyin jini, bayarwar jini na kwakwalwa:

• Vincetus. Yana kawar da matsanancin ƙwayar murjiyoyin jijiyoyin jini, yana inganta haɓakar jini, yana daidaita tafiyar matakai da hawan jini. Yana da tasiri mai amfani akan tsarin juyayi na tsakiya.
• Dihydroquercytin. Kwayoyi don inganta aikin zuciya da halin bugun jini. Normalize metabolism na lipid, rage glucose, rage jinkirin ci gaba da atherosclerosis.
• Acetylsalicylic acid. Sanya don tsarma jini da rage haɗarin ƙwanƙwasa jini.
• Forarin abinci na cholesterol. Yiwuwar ɗaukar su tare da daidaitaccen karuwa a LDL yana da shakka sosai. Ba kamar kwayoyi don rage ƙwayar jini ba, ana gwajin abinci ne kawai don aminci. A halin yanzu babu wani tabbaci game da ingancin warkewar su.Amma ana iya amfani dasu tare da ɗan karkatarwa a cikin matakin LDL daga al'ada tare da maganin rage cin abinci da daidaita rayuwa.

Duk allunan za a sha kawai kamar yadda likitanka suka umurce ka. Baya ga shan magunguna, mutanen da ke da yawan ƙwayar cholesterol dole su canza salon rayuwarsu da abin da suke ci. A wannan yanayin kawai maganin zai zama mafi inganci da inganci.

Littattafai

1. George T. Krucik, MD, MBA. Zabi na Statins don Rage Cholesterol, 2016
2. Susan J. Bliss, RPh, MBA. Cholesterol-Rage Magunguna, 2016
3. Omudhome Ogbru, PharmD. Magungunan Rage na Cholesterol, 2017
4. A. A. Smirnov. Nazarin kwatankwacin ingancin asibiti na almara na zamani

Abubuwan da marubutan aikin suka shirya
bisa ga tsarin edita na shafin.

Wanne ne mai kyau da arha?

Dangane da batun kula da lafiya ko ceton rayuka, farashin magani bai kamata ya zama matsayin zaɓi kawai ba, kodayake magungunan ƙwayoyin cuta masu arha ko da yaushe na iya zama da kyau. Dukkan abubuwan sun dogara da yanayin karfin jikin mutum zuwa ga abubuwan da ke aiki a jikin allunan kuma a kan matsayin lalacewar gabobin ta hanyar hypercholesterolemia (cholesterol). A yau a cikin lura da wannan yanayin ana amfani da su sau 2 nau'ikan miyagun ƙwayoyi:

• mutum-mutumi (HMG-CoA reductase inhibitors),
• fibrates (abubuwan da ake amfani da su na fibroic acid).

A cikin tsarin statins, ana amfani da allunan cholesterol tare da abubuwa masu aiki:

• arankumarn,
• lovastatin
• pitavastatin
• pravastatin
• rosuvastatin,
• simvastatin
• fluvastatin.

Theungiya mai aiki ta fibrate suna wakiltar abubuwa masu aiki:

• bezafibrat,
• fenofibrate
• choline fenofibrate,
• ciwanka.

Daga cikin magungunan wadannan rukunin, zaku iya zabar magungunan da ba su da tsada don cholesterol. Sunayen magunguna na magunguna na iya bambanta da tushe (abu mai aiki), saboda haka ya fi kyau a danƙa zaɓi zaɓin magunguna ga likita.

Shahararrun kwayoyi

Jerin sunayen mafi kyawun kwayoyi

Lokacin da mutum yayi ƙoƙarin neman jerin sunayen kyawawan kwayoyi, bai kamata ya je kantin magani ba, amma ga asibitin kuma da farko ya tabbata cewa yana buƙatar magungunan gaske na cholesterol.

Mafi kyawun waɗannan yawanci sun haɗa da magungunan da aka tsara don yin la'akari da duk kasawa na magungunan da suka gabata waɗanda suka bayyana a cikin aikin asibiti. Muna magana ne game da sababbin magunguna na abin da ake kira tsararraki na ƙarshe, suna cikin statins, kuma a cikin rukunin fibrates, da sauran magunguna. Tabbas, farashin waɗannan magungunan ya fi farashin farashin "talakawa" allunan cholesterol. Mun gabatar da jerin magunguna mafi kyau (tsada) na rage yawan lipid a cikin tebur.

Statins don rage darajar LDL a cikin jini

Kamar yadda za'a iya gani daga tebur, statins suna wakiltar rukuni mafi girma na kwayoyi don rage cholesterol jini. Kodayake wannan rukuni na magunguna har yanzu ba ya haifar da cikakken yarda ga ko dai marasa lafiya ko likitoci saboda yawan bayyanar cututtuka masu rikitarwa yayin aikin jiyya. Jagororin waɗannan kwayoyin suna dauke da jerin "kilomita" na contraindications, gargadi da haɗarin haɗari lokacin ɗauka. Abin da ya sa ya dace ka fahimci kanka da waɗannan magungunan rage ƙwayar lipid a cikakkun bayanai.

Domin masu karatu su fahimci sikelin cigaban masana'antar ta wannan hanyar, zamu buga wadannan lambobi:

• A rukunin mutum-mutumi akwai manyan abubuwa guda 7 (ana gabatar da sunayensu a sama),
• akwai alamun kasuwancin 88 na magungunan statin,
• fiye da mutane 3,500 sunaye da ke tattare da dukkanin magunguna na wannan rukunin masana'antun daban-daban.

A bayyane yake cewa ba shi yiwuwa a jera sunayen duka, saboda haka za mu mayar da hankali ga waɗanda suka fi shahara.

Atorvastatin

Ana samun magani don rage ƙwayar cholesterol Atorvasatin daga masana'antun da yawa a cikin ƙasashe daban-daban. Abubuwan da ke aiki shine alli na atorvastatin, wanda ke cikin ƙungiyar pharmacotherapeutic na magunguna masu rage ƙwaƙwalwar ƙwayar ƙwaƙwalwar ƙwaƙwalwa, zaɓin masu hana masu rage girman HMG-CoA reductase. Tasirinsa shine rage matakin lipoproteins mai ƙarancin ƙananan ƙwayoyi (LDL da VLDL), triglycerides da apolipoprotein B ta hanyar hana kwayar cholesterol a cikin hanta. Bugu da ƙari, a ƙarƙashin rinjayar atorvastatin, matakin HDL - lipoproteins mai ɗimbin yawa yana ƙaruwa kaɗan.

Groupungiyar kamfanonin magunguna KRKA da rassan su suna ba da allunan don Atoris na cholesterol tare da abu mai aiki atorvastatin. Kamar yawancin statins, suna da ingantaccen iko don rage haɗarin rikitarwa kamar angina pectoris da cututtukan zuciya na zuciya (26 da 16%, bi da bi). Sun toshe gwagwarmayar macrophages, suna hana katsewar wuraren wasan wuta da dama.

Aka sanya cikin yanayi na daidaitattun siffofin:

• tare da cututtukan hanta da karuwa a cikin transaminases fiye da sau 3 daga ƙwanƙolin babba na al'ada,
• karancin maganin lactase da sauran halaye masu alaƙa da rashin maganin lactose,
• tare da kwarangwal tsoka pathologies,
• ciki da lactation,
• shekara 18 da haihuwa.

Allunan suna cikin allurai na 30, 60 da 80 MG. Bayyananun - fararen kwalabe na farin zagaye ko siffar m.

Don rage yawan ƙwayar cholesterol da rage haɗarin rikicewar cututtukan zuciya, bisa ga umarnin don amfani, Novostat miyagun ƙwayoyi kuma an yi niyya (don Allah a kula - ba Novostatin). Wasu lokuta baƙi zuwa kantin magani (musamman waɗanda ke neman magungunan don rage ƙwayar cholesterol bisa ga ra'ayoyin abokai) suna rikitar da sunan miyagun ƙwayoyi tare da wani magani kuma ku gaya musu su ba da wannan tatsuniyoyin Novostatin. Irin waɗannan marasa lafiya marasa hankali kada suyi mamakin idan, a maimakon wakili mai saurin rage kiba, ana ba su Nystatin antifungal.

Novostat ya dogara da atorvastatin kuma yana da duk kayan aikin magani na wannan kayan aiki.

Kamfanin Czech na Zentiva yana kera allunan Torresam na Torvacard na kananan kwayoyi. Kamar yadda yake tare da duk ƙwayoyi tare da wannan sashi mai aiki, umarnin don amfani suna da girman gaske, wanda ke nuna buƙatar yin amfani da hankali da sarrafawa na Torvacard. Sakamakon sakamako masu illa na yau da kullun - hyperglycemia, dyspepsia, flatulence, varinci, maƙarƙashiya, ƙwanƙwasawa, aikin lalata hanji, ciwon kai, halayen rashin lafiyan - halayyar yawancin magungunan statin.

Rosuvastatin

Allunan tare da kayan aiki iri ɗaya sune kwayoyi masu ruwan hoda a cikin siffar zagaye. Hanyar aiwatar da rosuvastatin yana da kama da magunguna na dukkanin statins, kayan yana cikin mahimmancin gasa, zaɓin masu hanawa na HMG-CoA reductase. An sanya su:

• tare da farko, gauraye da hereditary hypercholesterolemia,
• sabar, kamar,
• don rage cholesterol a atherosclerosis domin hana ci gabanta.

Rosuvastatin yana da tasiri a cikin rigakafin CVD da rikitarwa a cikin marasa lafiya tare da abubuwan haɗari - hauhawar jijiya, tsinkayar iyali ga cututtukan jijiyoyin zuciya, jarabar nicotine.

Rosuvastatin Calcium sashi ne mai aiki da allunan Roxer wanda Krka ya kera su. Waɗannan fararen kwalaben fararen rubutu ne masu alama "5" a gefe guda. A cikin abin da ya sa magini, kamar yadda yake a cikin allunan da ke sama don cholesterol, akwai lactose, kamar yadda marasa lafiya da sukari na rashin haƙuri ko ƙarancin lactase ya kamata su sani game da.

Rosart hypoliplera wakili yana cikin rukuni na kwamfutar hannu mai rahusa mai rahusa akan rosuvastatin. Yana samuwa a cikin zaɓuɓɓukan sashi huɗu:

• 5 MG - fararen kwalayen convex zagaye tare da embossed "ST1" a gefe guda,
• 10 MG - ruwan hoda, allunan zagaye, masu alama "ST2",
• 20 MG - kwayoyi masu zagaye masu ruwan hoda, masu taken "ST3",
• 40 MG - Allunan suna da siffar m da kuma zane "ST4".

Allunan na Krestor ana yin su ta wasu rassa daban-daban na kamfanin Ingila Astra Zeneca kuma sune Statin da aka fi yin nazari akan rosuvastatin. Saboda wannan dalili, ana ɗaukar su ɗayan mafi kyawun (kuma ba arha ba) a cikin nau'ikan magungunan rage ƙwayar cutar lipid. Allunan farko suna da sauƙin bambancewa ta hanyar fim mai rawaya mai haske da embossed “ZD45225” a gefe ɗaya.

Atinasar Czech da aka yi da statin Rosucard (ana ɗaukar sigar aiki da sunan) yana cikin zaɓuɓɓukan sashi uku:

• 10 MG - convex elongated light kwayoyi masu ruwan hoda a cikin harsashi mai polymer,
• 20 MG - mai kama da sifar ga waɗanda suka gabata, amma dabam dabam a cikin launi da harsashi, ga shi ruwan hoda,
• 40 MG sune magungunan ruwan hoda mai duhu.

Rosucard Har ila yau, yana nufin magungunan tsada, kodayake jerin halayen da ba su da kyau da taka tsantsan don amfaninsu bai gaza da na wasu gumakan ba. Idan kun dauki wannan magani kamar yadda aka umurce ku kuma a karkashin kulawa na likita, haɗarin rikitarwa ba kadan bane.

Sauran kwayoyi don ƙwayar cholesterol

Idan, bayan haɗuwa tare da statins, sha'awar da za a bi da su ta ragu (kuma da yawa daga cikin marasa lafiya suna jin tsoron shan su), yana da daraja a kula da wasu magunguna waɗanda ke rage cholesterol. Waɗannan magunguna ne na ƙungiyar fibrate - abubuwan da ake amfani da su na fibroic acid, waɗanda ke haɓaka lipolysis da kuma kawar da abin da ake kira atherogenic lipoproteins (LDL da VLDL) daga jini, kazalika da rage taro na triglycerides. Wadannan kwayoyin maganin cholesterol ba su da arha, amma zaku iya ɗaukar matakan analogues na aikin Turkawa (alal misali, Lipofen), waɗanda suke sau biyu mafi arha fiye da magungunan Faransa.

Baya ga fibrates da statins, lipid-lowering therapy yana amfani da inhibitors na cholesterol tare da sinadarin mai aiki na ezetimibe (Ezetrol), wanda yake matukar hana shi (toshe) sha daga kwalayen kwayoyi da kuma sterols a cikin hanji.

Wanne ya fi kyau a sha?

Me za a zaɓa daga cikin jerin irin waɗannan magunguna masu rikitarwa, waɗanne ne mafi kyawun sha? Statins da fibrates suna firgita tare da tasirin su akan hanta da kasusuwa, tsoffin magunguna suna da tsada. Likitocin sun ba da shawarar cewa duk da haka fara da hankali da sarrafawa na mutum-mutumi kuma, idan ya nuna cewa suna da tasiri kuma ana haƙuri da su, to ana iya samun cikakkiyar magani.

Idan statins ko fibrates basu dace ba, akwai wasu allunan daga kungiyoyin gungun cholesterol absorption inhibitors ko mahaɗa masu haɗin gwiwa akan su.

Wani lokaci zaku iya jin cewa ana iya amfani da ƙarin makamashi na bioactive (BAA) a matsayin allunan cholesterol. Amma bisa ga umarnin don amfani, samfuran tare da sunan cinikayyar Energia sune bitamin da abubuwan haɗin ma'adinai waɗanda aka ƙaddara ga mutanen da basu da ƙarfi a wasu abubuwan binciken abubuwan da bitamin. Gaskiyar cewa Energy shine allunan cholesterol ba a ambata a cikin bayanin ba. Magungunan gaba ɗaya ba magani bane, ko ma mai karfafa metabolism, sabili da haka, ba a ba da shawara ku ba shi rawar da wakilin rage rage kiba ba.

Da alama marasa lafiya za su rikitar da makamashi tare da haɓakar rage ƙwayar lipid na Italiyanci ko Emewetiya dangane da simvastatin da ezetimibe (statin da cholesterol absorption inhibitor). Wannan ingantacciyar warkarwa ce ga hypercholesterolemia.

Wajibi ne a faɗi game da kwayoyin Alisat (ko kuma kawai "Tafarnuwa"), waɗanda mutane da yawa suna ɗauka su zama ƙwayoyin cholesterol.Wannan ƙarin abincin yana da niyyar cika jiki rashi na allicin, abu mai ma'ana tare da antifungal da kwayoyin cuta.

Idan da gaske kuna son a kula da ku ba tare da kwayoyin hana daukar ciki ba, amma tare da kayan abinci, zaku iya kula da maganin Aterolex capsules wadanda ke taimakawa inganta haɓakar lipid, daidaita amfanin su tare da likita.

Wanne ne mara tsada?

Idan kun zaɓi magunguna don rage cholesterol jini daga rukuni mai arha, to ya kamata ku neme su a cikin magungunan ƙungiyar statin:

• Atorvastatin (tare da abu guda mai aiki),
• Cardiostatin (lovastatin),
• Reddistatin (rosuvastatin),
• Vasilip (simvastatin).

A yau, waɗannan sune magunguna mafi arha don hawan jini.

Tare da karancin sakamako masu illa

Babban burin hada sababbin magunguna shine rage yawan tasirin sakamako yayin kiyaye babban tasirin maganin. Sabili da haka, allunan daga sabon cholesterol - masu hana cholesterol sha a cikin hanji (Ezetrol) - ana ɗauka mafi kyawun kwayoyi masu saurin rage kiba. Wannan bawai yana nufin cewa waɗannan magungunan basu da illa ba - suna dasu kuma jerin su suna da yawa. Amma bisa ga umarnin don amfani, waɗannan alamomin marasa amfani ana lura da su cikin rukunan “ba da jimawa ba” da “da wuya”, waɗanda ke magana da amincin tsaro.

Shin zai yiwu a rage sauri da inganci?

Zai yi wuya ga mutumin da ba a amfani dashi don yin biyayya ga yanayi don yarda da buƙatar ɗaukar magunguna na dogon lokaci kuma ya bi abincin. Irin waɗannan marasa lafiya basu da haƙuri kuma suna neman magungunan da ke rage ƙwayar cholesterol cikin sauri da inganci. Kuma a nan kawai ba za a iya samun irin waɗannan allunan ba, tunda maido da ƙwayar mai da ake buƙata don a daidaita matakan cholesterol a cikin jini dogon lokaci ne, sannu a hankali. Ba shi yiwuwa a warke da cutar tare da wasu allunan, wanda wasu lokuta suka bunkasa tsawon shekaru. Sabili da haka, ya kamata marasa lafiya da ke fama da hypercholesterolemia su kasance masu shiri don jinya don tsawan lokaci da kuma mummunan canje-canje a salon rayuwa.

Neman Batun

Binciken haƙuri game da wasu abubuwa masu aiki na magungunan rage ƙwayar lipid suna da ban sha'awa, suna ba ku damar fahimtar wanne ne ya fi haƙuri, wanda ya fi tasiri.

Dangane da kimantawa na masu haƙuri, yawancinsu ana bi da su tare da mutum-mutumi da aka sanya musu a asibitin. Daga wannan rukuni na kwayoyi, atorvastatin da rosuvastatin tushen allunan cholesterol sun sami kyakkyawan bita. A hanyar, ana kiran rosuvastatin mafi kyau, saboda a lokacin gudanar da mulkinsa yawancin marasa lafiya ba su sami matsala ba.

Daga cikin matan, Tricor ya sami kyakkyawan bita.

Ana kiran Ezetrol mafi kyawun kwayar cholesterol, amma likitoci da marasa lafiya sun lura cewa "magani ne mai tsada."

Yaya za a rage cholesterol ba tare da kwayoyi ba?

Ganin hatsarori da farashin kuɗin jiyya na jinya, da yawa daga cikin marasa lafiya suna neman nemo wani magani wanda ba magani ba wurin maganin rage kiɗa. Kuma irin waɗannan hanyoyin suna wanzu, dukda cewa suna buƙatar himma ta musamman, horo da haƙuri, tunda waɗannan hanyoyin ba zasu bada sakamako mai sauri ba. Tambaya ce ta kawar da irin waɗannan abubuwan masu tayar da hankali na tashin hankali na ƙwaƙwalwar ƙwayar cuta kamar rashin motsa jiki, halaye marasa kyau da rashin abinci mai gina jiki.

Hadadden matakan rashin magunguna yakamata su haɗa da tsari na lokacin tare da hutawa da rage damuwa.

Bayan kawar da abincin abinci mai cutarwa, zaku iya cire tsarin narkewa daga buƙatu don ɗaukar kitsen da ya wuce kima, wanda zai iya yin tasiri ga bayanin martaba. Kuma don daidaita cholesterol na jini, ya zama dole a bi wani abinci na musamman mai rage yawan abinci mai narkewa wanda ke taimakawa tsayayyen metabolism.

Kwayoyi masu juna biyu

Idan, lokacin yanke shawarar gwaji na ƙirar ƙwayar cuta, an bayyana cewa ƙimar ƙwaƙwalwar ƙwayar cuta ta wuce al'ada, an wajabta magani. Mafi sau da yawa, likita ya ba da izini ga rukuni na statins waɗanda ke da tasiri. Koyaya, yana da mahimmanci a tuna cewa yayin daukar ciki waɗannan magungunan suna contraindicated.

A cikin irin wannan yanayin, an wajabta Hofitol ga mata masu juna biyu. Ka'ida ta halatta ba ta wuce allunan uku ba a rana. Kada ku sami magani na kai. Don samun alƙawari, zai fi kyau neman taimakon ƙwararrun masani.

Rayuwa mai aiki

Suarancin aiki na jiki yana haifar da tsayayyewar jini da ɗimbin yawa (ajiya) na ajiyar kuzari mara ƙarfi a cikin jiki mai yawa. An adana su a kusan dukkanin gabobin mahimmanci, suna tsoma baki tare da aikinsu na yau da kullun da rushe metabolism na mai. Canza salon rayuwa zuwa karuwar aiki yana taimakawa inganta hawan jini da daidaita dukkan tsari, gami da haɓakar mai. Abin da ya sa yana da matukar muhimmanci a koyaushe a cikin ilimin motsa jiki - kullun motsa jiki na safe, gudana, tafiya, iyo sau da yawa a mako, motsa jiki na yau da kullun a cikin aikin (musamman idan yana da hankali).

Ana Share tasoshin tare da magunguna

Magungunan magungunan gargajiya ma sun sami wuri a cikin rage ƙwayar lipid. Yanayi yana da arziki a cikin tsirrai da ke taimakawa ci gaban hanyoyin tafiyar da rayuwa da rushewar kitse. Waɗannan kaddarorin sune tushen girke-girke na kwayoyi waɗanda ke tsarkake tasoshin jini da ƙananan cholesterol. Lokacin fara magani tare da magunguna na jama'a, ya kamata a tuna cewa magani na ganye shine tsari mai tsawo, kuma zasu iya samun sakamako masu illa da contraindications don amfani.

Shahararrun kwayoyi

Daga cikin mafi arha, amma ingantacce yana nuna bambanci:

• lipoic acid
• Vasilip
• Simvastatin
• Simvor
• allunan tafarnuwa
• Simvagexal
• Simvakard.

Mafi mashahuri kuma galibi ana sanya su sune:

1. Aterol na ɗaya daga cikin magungunan da suka fi tasiri a gwagwarmayar cutar cholesterol. Daga cikin manyan fa'idodin su shine rashin sakamakon mummunan sakamako, ɗan gajeren magani (kusan darussan kusan uku sun isa), abubuwan da aka haɗa a cikin abubuwan da ke ciki.
2. Statins na sabon ƙarni da simvastatin.
3. Ezetrol karamin kayan aiki ne sananne, amma yana da tasiri. Ayyukanta na da nufin hana shan kwayar cholesterol, yayin da wannan ba ya toshe tsari, amma yana rage shi.
4. Kifi mai da omega 3.

Idan ilimin halittar jini ya nuna yawan kwayar cutar kwayar cuta, dole ne a tuntuɓi ƙwararrun likita wanda zai ba da magani da ya dace. Idan baku dauki wasu matakai ba don rage mai nuna alama, to hadarin da ke tattare da mummunan sakamako yana kara yawa, wanda zai iya haifar da bugun zuciya da bugun zuciya.