Hypoglycemic miyagun ƙwayoyi "Starlix"

Starlix magani ne na hypoglycemic wanda aka samo daga phenylalanine amino acid. Magungunan suna ba da gudummawa ga ƙaddamar da insulin na hormone a cikin mintina 15 bayan mutumin ya ci abinci, yayin da sauƙaƙewa a cikin sukari na jini ya bushe.

Godiya ga wannan aikin, Starlix baya barin ci gaban hypoglycemia idan, alal misali, mutum ya rasa abinci. Ana siyar da miyagun ƙwayoyi a cikin nau'ikan allunan da aka sanya fim ɗin, kowane ɗayansu ya ƙunshi 60 ko 120 MG na kwayoyin halitta mai aiki.

Hakanan an haɗa shi da magnesium stearate, titanium dioxide, lactose monohydrate, macrogol, jan ƙarfe baƙin ƙarfe, sodium croscarmellose, talc, povidone, microcrystalline cellulose, colloidal anhydrous silicon dioxide, hypromellose. Kuna iya siyar da magani a kantin kantin ko kantin sayar da kayan sana'a, a cikin fakitin 1, 2 ko 7 murhun ciki, buhun gado guda ya ƙunshi allunan 12

Tsarin saki, abun da aka shirya da shiryashi

· Dioxide na silsilar anhydrous (colloidal),

· Titanium dioxide E171,

Amasamai.60A cikin wani kwali na kwali na iya samun 1, 2, 5, 7, 10, 30 blister na allunan 12 kowannensu. Allunan launuka a cikin harsashi mai rawaya, mai alama STARLIX a gefen gaba. A baya - kashi na maganin "120".120 Allunan tare da rubutun STARLIX - a gefe guda kuma alamar "180" - a gefe. Allunan jan suna da shafi, fim mai kyau da launi ja.180

Aikin magunguna

Kateglinide asalin halitta ne. Abubuwan sun mayar da farkon insulin. Increasearuwar yawan haɗarin hormone yana hana matakin sukari da glycosylated haemoglobin A1C.

Hormoneara yawan haɓakar hormone yana da tasiri na mintina 15 bayan cin abinci. Sa'o'i 3.5 masu zuwa, matakin insulin ya koma sigar asalin sa, da guje wa hyperinsulinemia.

MUHIMMIYA Sirrin insulin zai danganta ne kai tsaye da yawan sukari a cikin jini.

Ikon da miyagun ƙwayoyi, har ma da rage yawan kuzari, don sarrafa matakin hormone yana ba ku damar hana faruwar cututtukan jini a lokacin lalacewar jiki, mai haƙuri ya ƙi cin abinci.

Bayanin maganin

A miyagun ƙwayoyi yana da tabbatacce sake dubawa. Zai taimaka wajen dawo da farkon asirin insulin, tare da raguwa a cikin postprandial taro na jini da glycated haemoglobin.

Irin wannan hanyar aiki tana da mahimmanci ga masu ciwon sukari, saboda wanda matakan glucose na jini ke zama al'ada. A cikin cututtukan mellitus, wannan yanayin insulin insulin ya lalace, yayin da nateglinide, wanda shine ɓangare na miyagun ƙwayoyi, yana taimakawa wajen dawo da farkon farkon aikin hormone.

Ba kamar kwayoyi iri ɗaya ba, Starlix ya fara samar da insulin sosai a cikin mintina 15 bayan cin abinci, wanda ke inganta yanayin masu ciwon sukari kuma yana daidaita haɗuwar glucose a cikin jini.

1. A cikin awanni huɗu masu zuwa, matakan insulin sun koma ƙimar su ta asali, wannan yana taimaka wajan hana aukuwar cututtukan postprandial hyperinsulinemia, wanda a nan gaba zai haifar da ci gaba da cututtukan hypoglycemic.
2. Lokacin da yawan sukari ya ragu, samar da insulin ya ragu. Magungunan, bi da bi, yana sarrafa wannan tsari, kuma tare da ƙimar ƙarancin glucose, yana da tasiri mai rauni akan ɓoyewar hormone. Wannan wani tabbataccen abu ne wanda ba ya barin ci gaban hypoglycemia.
3. Idan ana amfani da Starlix kafin abinci, allunan suna cikin sauri cikin hanji. Matsakaicin tasirin maganin yana faruwa a cikin sa'a mai zuwa.

Kudin maganin yana dogara da wurin da kantin magani yake, don haka a Moscow da Foros farashin kunshin 60 na MG shine 2300 rubles, fakitin da aka auna 120 MG zai biya 3000-4000 rubles.

Starlix na miyagun ƙwayoyi: umarnin don amfani

Duk da gaskiyar cewa miyagun ƙwayoyi suna da sake dubawa masu inganci, ya zama dole ku nemi shawara tare da likitanku kafin amfani da maganin.

Allunan ya kamata a dauki minti 30 kafin cin abinci. Don ci gaba da jiyya tare da wannan magani shi kadai, sashi shine 120 mg sau uku a rana kafin abinci.

In babu bayyanar tasirin warkewa, ana iya ƙara yawan zuwa 180 mg.

Yayin aikin jiyya, mai haƙuri yana buƙatar sarrafa matakin sukari na jini da daidaita sashi gwargwadon bayanan da aka samo. Don tantance yadda amfanin magungunan yake, ana yin gwajin jini don alamu na glucose daya bayan biyu zuwa awa biyu bayan cin abinci.

Wani lokaci ana ƙara ƙarin wakili na hypoglycemic zuwa ƙwayoyi, yawancin lokuta Metformin. Ciki har da Starlix na iya aiki a matsayin ƙarin kayan aiki a cikin maganin Metformin. A wannan yanayin, tare da raguwa da kusantowa na HbA1c da ake so, an rage yawan sashi na Starlix zuwa 60 MG sau uku a rana.

Yana da mahimmanci a la'akari da cewa allunan suna da wasu abubuwan hana haihuwa. Musamman, ba za ku iya ɗaukar magani tare da:

• Rashin hankali
• Insulin-da ke fama da ciwon sukari mellitus,
• Mai fama da rauni na hanta,
• Ketoacidosis.
• Hakanan, magani yana contraindicated a cikin yara, lokacin daukar ciki da lactation.

Maganin ba ya buƙatar daidaitawa idan mai haƙuri yana ɗaukar Warfarin, Troglitazone, Diclofenac, Digoxin. Hakanan, babu wata ma'amala mai ma'ana da wasu magungunan maganin cututtukan da aka bayyana.

Magunguna kamar su Captopril, Furosemide, Pravastatin, Nicardipine. Phenytoin, Warfarin, Propranolol, Metformin, Acetylsalicylic acid, Glibenclamide ba su shafar hulɗar da keɓaɓɓun abubuwa tare da sunadarai.

Yana da mahimmanci a fahimci cewa wasu kwayoyi suna haɓaka metabolism na glucose, sabili da haka, yayin ɗaukar su tare da maganin hypoglycemic, canje-canje na glucose.

Musamman, hypoglycemia a cikin sukari mellitus yana haɓaka ta hanyar salicylates, masu hana beta-blockers, NSAIDs da MAO inhibitors. Magungunan Glucocorticoid, thiazide diuretics, sympathomimetics da hormones thyroid suna ba da gudummawa ga rauni na hypoglycemia.

1. A cikin nau'in 2 na ciwon sukari na mellitus, dole ne a kula da kulawa ta musamman, tunda haɗarin haɓakar haɓakar jini yana da girma sosai. Musamman, yana da mahimmanci a kula da matakan sukari na jini ga mutanen da ke aiki tare da keɓaɓɓun hanyoyin ko tuki motocin.
2. Patientsarancin marasa haɗarin, tsofaffi, marasa lafiya da ke fama da matsalar ƙwayar ƙwayar cuta ko rashin ƙarfi, sun fada cikin haɗarin. Yawan sukari na jini zai iya raguwa idan mutum ya sha barasa, yana fuskantar hawan jiki, haka kuma yana shan wasu magungunan hana haihuwa.
3. A lokacin jiyya, mara lafiya na iya fuskantar tasirin sakamako a cikin nau'in ƙara yawan shaye-shaye, rawar jiki, farin ciki, yawan ci, tashin zuciya, tashin zuciya, rauni, da malaise.
4. Haɗarin sukari a cikin jini na iya zama ƙasa da 3.3 mmol / lita. A cikin lokuta mafi wuya, ayyukan enzymes na hanta a cikin jini yana ƙaruwa, amsawar rashin lafiyan, tare da ƙari, ƙaiƙayi da urticaria. Hakan yana iya yiwuwa ciwon kai, zawo, dyspepsia, da zafin ciki.

Kiyaye miyagun ƙwayoyi a zazzabi a daki, nesa da hasken rana kai tsaye da yara. Rayuwar shelf shekara uku, idan lokacin ajiyar ya ƙare, ana zubar da maganin kuma ba'a amfani dashi don manufar da aka nufa.

Analogues na miyagun ƙwayoyi

Don samfurin abu mai aiki, cikakkun analogues na miyagun ƙwayoyi basu wanzu. Koyaya, a yau yana yiwuwa a sayi magunguna tare da irin wannan tasirin waɗanda ke sarrafa sukarin jini kuma ba sa barin hauhawar jini.

Ana ɗaukar allunan Novonorm don ciwon sukari na 2, idan abinci mai warkewa, rage kiba da aiki na jiki ba su taimakawa daidaita yanayin mai haƙuri. Koyaya, irin wannan magani yana cikin contraindicated a cikin nau'in 2 mellitus na ciwon sukari, ketoacidosis mai ciwon sukari, precoma na sukari da coma, da gazawar hanta mai ƙarfi. Kudin tattarawa allunan kwatankwacin 130 rubles ne.

Ana amfani da maganin Diagnlinide don nau'in ciwon sukari na 2 na sukari guda biyu, tare da Metformin, idan ba zai yiwu a daidaita alamomin glucose na jini ba ta hanyar daidaitattun hanyoyin.

Magungunan sun kamu a cikin nau'in 1 mellitus na ciwon sukari, ketoacidosis masu ciwon sukari, ciwon sukari da coma, cututtuka masu yaduwa, ayyukan tiyata da sauran yanayin da ke buƙatar maganin insulin. Farashin magani ya bar 250 rubles.

Ana ɗaukar allunan Glibomet don ciwon sukari na 2. An zabi sashi daban-daban, gwargwadon matsayin metabolism.

An sanya maganin a cikin cututtukan cututtukan cututtukan ketoacidosis da nau'in 1 na ciwon sukari na mellitus, lactic acidosis, ciwon sukari da coma, hypoglycemia, hypoglycemic coma, hanta ko gazawar koda, da cututtuka na kamuwa da cuta. Kuna iya siyan irin wannan kayan aiki don 300 rubles.

Magungunan Glucobai yana da tasiri ga nau'in 1 da nau'in ciwon sukari na 2. Matsakaicin adadin yau da kullun shine 600 MG kowace rana. Ana ɗaukar magani ba tare da tauna ba, tare da ɗan ƙaramin ruwa, kafin abinci ko awa daya bayan cin abinci. Farashin ɗayan fakitin allunan shine 350 rubles.

A cikin bidiyon a cikin wannan labarin, likita zai ba da shawarwari kan yadda za a runtse sukari na jini da dawo da ɓoye insulin.

Pharmacokinetics

Bayan gudanarwar bakin, an tattara nau'in kwayoyin halitta a cikin karamin hanjin, yana kaiwa zuwa mafi yawan abin da bai fi ƙarfin awa guda ba. Bioavailability na 72%. Lokaci don isa Cmax yana da 'yanci daga sashi. Shan magani tare da abinci yana sanya wahalar sha maganin. Bioavailability bai canza ba.

Kateglinide ya ɗaura nauyin sunadaran plasma da kashi 98%.

Abubuwan da ke aiki suna gudana canji a cikin hanta tare da aiki mai ƙarfi na cytochrome P450 isoenzymes. Bayan an kammala aiwatar da ƙari na xyungiyoyin hydroxyl, an kirkiro metabolites uku na abubuwa masu aiki, wanda kodan ke cire shi. 7-16% na farkon sashi ya zauna canzawa. Tare da feces, wani 10% na abu yana barin jiki. Rabin rayuwar Starlix kusan awa daya da rabi.

Nau'in nau'in ciwon sukari na 2 da ƙarancin tasiri na aiki a jiki da kuma maganin abinci.

Kayan magunguna

Farin insulin da wuri a yayin mayar da hankali ga motsawar glucose wani tsari ne mai mahimmanci don kiyaye matakan glucose na al'ada. A cikin nau'in 2 na ciwon sukari na mellitus, ana lura da cin zarafi / rashi wannan lokacin insulin insulin. Karkashin tasirin nau'in abinci wanda aka ɗauka kafin abinci, an sake dawo da farkon (ko na farko) na ɓoye insulin. Hanyar wannan sabon abu shine haɗin kai da sauri da kuma sake juyar da magani tare da tashoshin K + -ATP-dogara da β-sel na fitsari. Zaɓin kateglinide dangane da tashoshin K + -ATP mai dogaro da ƙwayoyin ƙwayoyin ƙwayar cuta shine sau 300 fiye da hakan dangane da tashoshin zuciya da jijiyoyin jini.

Kateglinide, ba kamar sauran wakilai na magana da ƙwayar cuta ba, yana haifar da alamar insulin a cikin mintina 15 na farko bayan cin abinci, saboda wanda hawainiya ke hawa bayan hawa ("kololuwa") a cikin taro na hawan jini. A cikin awanni 3-4 na gaba, matakin insulin ya koma ga dabi'unsa na asali, don haka gujewa ci gaban hyperinsulinemia na postprandial, wanda zai iya haifar da jinkirin hypoglycemia.

Sirrin insulin ta hanyar β-sel na pancreas wanda ke haifar da nau'in kwayar halitta ya dogara da matakin ƙwayar glucose a cikin jini, shine, yayin da hankali ke raguwa, yawan narkewar insulin ya ragu. Hakanan, yawan shiga lokaci guda ko kuma samar da maganin glucose yana haifar da karuwar adadin insulin. Abun iyawa Starlix a low yawa na glucose a cikin jini, mara ƙima akan insulin ɓoyewa shine ƙarin abubuwan da ke hana haɓakar haɓaka, alal misali, a lokutan tsallake abinci.

Damuwa. Lokacin shan kwayoyin Starlix kafin abinci, ana saukar da sashin ƙasa da sauri daga narkewa. Lokaci don isa Cmax ƙasa da awa 1. Amfani da miyagun ƙwayoyi shine kusan 72%. Ga alamu kamar AUC da Cmax, magungunan ƙwayoyin cuta na nateglinide a cikin kewayon kashi daga 60 MG zuwa 240 MG ne mai layi a cikin marasa lafiya da ke da nau'in ciwon sukari na 2 sau 3 / rana don mako guda.

Rarraba. Theuntatar da keɓaɓɓen tarin kwayoyin sunadarai (yawancinsu tare da albumin, zuwa ƙarancin ƙasa - tare da acidic α1-glycoprotein) shine kashi 97-99. Matsakaicin ɗaukar nauyin furotin ba ya dogara da haɗuwa da nau'in kateglinide a cikin plasma a cikin kewayon binciken 0.1-10 μg / ml. Vd lokacinda ya isa daidai yake da lita 10.

Tsarin rayuwa. Kateglinide yana da mahimmancin metabolized a cikin hanta tare da halartar microsomal isoenzymes na cytochrome P450 (70% isoenzyme CYP2C9, 30% CYP3A4). Babban 3 metabolites na nateglinide sakamakon halayen hydroxylation suna da lokuta da dama ƙananan ayyukan aikin magani idan aka kwatanta da kayan farawa.

Kiwo. Ana cire kwayar halittar jiki daga jiki cikin hanzari - a cikin awanni 6 na farko bayan shigowa, kusan kashi 75% na kashi an fesa shi ne a cikin fitsari. Ana aiwatar da aikin motsa jiki ne musamman da fitsari (kimanin kashi 83% na kashi), akasari a cikin hanyar metabolites. Kimanin 10% an fesa a cikin feces. A cikin kewayon kashi na binciken (har zuwa 240 mg sau 3 / rana), ba'a lura da cumlation ba. T1 / 2 shine 1,5 hours.

Lokacin da aka tsara nau'in kateglinide bayan cin abinci, ƙoshin shanshi zai lalace - Tmax yana tsawaita, Cmax yana raguwa, yayin da cikar ɗaukar (darajar AUC) baya canzawa. Dangane da abin da ya gabata, an bada shawara don amfani Starlix kafin abinci.

Babu bambance-bambance masu mahimmanci na asibiti da aka samo a cikin sigogin magunguna na sashin kateglinide a cikin maza da mata marasa lafiya.

Umarni na musamman. Tsarin magani Starlix beta-blockers suna ƙaruwa .Daga shan Starlix, ya kamata ka guji shan giya, saboda wannan na iya haifar da haɓaka sakamako masu illa.

Hanyar aikace-aikace

Ya kamata a ɗauki Starlix kafin abinci. Tsakanin lokaci tsakanin shan miyagun ƙwayoyi da cin abinci kada ya wuce minti 30. A matsayinka na mai mulki, ana ɗaukar maganin nan da nan kafin abinci.

Lokacin amfani da Starlix azaman monotherapy, maganin da aka bada shawarar shine 120 MG 3 sau / rana (kafin karin kumallo, abincin rana da abincin dare).

Hakanan za'a iya amfani da Metformin don marasa lafiya da ke karɓar maganin ciwon maganin ciwon kafa na Starlix kuma suna buƙatar wani magani na hypoglycemic. Akasin haka, marasa lafiya da suka fara karbar maganin metformin ana iya tsara su Starlix a gwargwadon nauyin 120 mg sau 3 / rana (kafin abinci) azaman kayan aiki. Idan, a kan asalin maganin metformin, darajar HbA1c ta kusanci darajar da ake so (ƙasa da 7.5%), kashi na Starlix na iya ƙasa da - 60 MG sau 3 / rana.

Babu wani bambance-bambance a cikin inganci da amincin Starlix a cikin tsofaffi marasa lafiya da kuma na yawan jama'a. Bugu da kari, shekarun marasa lafiya bai shafi sigogin magani na Starlix ba. Sabili da haka, ga marasa lafiya tsofaffi, ba a buƙatar gyaran tsari na musamman akan sashi ba.

Ba a yi nazarin tasiri da amincin Starlix a cikin yara ba, saboda haka ba a ba da shawarar ganawa da yara ba.

A cikin marasa lafiya masu rauni mai laushi zuwa matsakaici na matsakaita, ba a buƙatar daidaita sashi ba. Ba'a ba da shawarar yin amfani da miyagun ƙwayoyi a cikin marasa lafiya da ke fama da rauni na hanta, tunda har yanzu ba a samo bayanan gwaji na asibiti ba.

A cikin marasa lafiya da ke fama da rauni na aiki na ƙarancin bambanci (ciki har da waɗanda ke kan cututtukan hemodialysis), ba a buƙatar daidaita tsarin gyaran sashi ba.

Contraindications

nau'in ciwon sukari

Yin hulɗa tare da wasu magunguna

A cikin binciken da aka yi a cikin vitro ya nuna cewa nateglinide yana da mahimmancin metabolized ta cytochrome P450 isoenzymes - CYP2C9 (70%) da CYP3A4 (30%).

Nateglinide ba ya tasiri da kayan aikin magani na warfarin (canzawa don CYP3A4 da CYP2C9), diclofenac (musanya ga CYP2C9), troglitazone (inducer na CYP3A4) da digoxin. Saboda haka, tare da alƙawaran lokaci guda Starlix kuma magungunan kamar warfarin, diclofenac, troglitazone da digoxin basu buƙatar daidaita sashi. Babu kuma ma'amala da yawa ta hanyar magunguna Starlix tare da sauran magungunan antidiabetic na baka kamar metformin da glibenclamide.

Tun da nateglinide yana da ɗaurin nauyi ga furotin plasma, gwaje-gwajen a cikin vitro sunyi nazarin hulɗarta tare da wasu kwayoyi masu ɗaukar nauyin furotin, irin su furosemide, propranolol, captopril, nicardipine, pravastatin, warfarin, phenytoin, acetylsalicylic acid, glibenclamide da metformin. An nuna cewa waɗannan kwayoyi ba su tasiri da haɗin kan nateglinide tare da sunadaran plasma. Hakanan, nau'in kwayar halitta baya cire propranolol, glibenclamide, nicardipine, warfarin, phenytoin, da acetylsalicylic acid daga ɗaura zuwa furotin.

Ya kamata a ɗauka cewa wasu ƙwayoyi suna shafar metabolism na glucose, sabili da haka, lokacin da aka tsara su lokaci guda tare da magungunan hypoglycemic, gami da Starlixcanje-canje a cikin taro yana yiwuwa kuma ana buƙatar kulawa da lafiya. Ana iya inganta tasirin hypoglycemic tare da gudanarwa na lokaci guda na NSAIDs, salicylates, MAO inhibitors, masu hana beta-blockers zaɓi. Akasin haka, za a iya raunana tasirin hypoglycemic tare da gudanar da aikin sau ɗaya na thiazide diuretics, glucocorticoids, sympathomimetics, da kuma shirye-shiryen homonin thyroid.

Yawan abin sama da ya kamata

Adadin kararraki Starlix ba tukuna aka bayyana.

Bayyanar cututtuka: dangane da ilimin aikin hanyar maganin, ana iya ɗauka cewa babban abin da ya haifar da yawan ƙwayar cuta zai iya kasancewa hypoglycemia tare da alamun bayyanar cututtuka na bambancin wahala.

Jiyya: Hanyar da za a bi don magance cututtukan cututtukan zuciya an tabbatar da ƙimar bayyanar cututtuka. Tare da tsabtataccen tunani da kuma rashin bayyanar cututtuka na jijiyoyin jini, ana nuna ciwan glucose / sukari, gami da daidaita suturar ƙwayoyi da / ko abinci. A cikin babban rauni na jini, tare da bayyanar cututtuka na jijiya (coma, raɗaɗin), ana nuna maganin glucose mai narkewa. Amfani da maganin hemodialysis don cire nateglinide daga cikin jini ba shi da tasiri saboda ɗaukar nauyin da yake ɗauka zuwa ga garkuwar plasma.

Yanayin ajiya

Ya kamata a adana miyagun ƙwayoyi a zazzabi da ba ya wuce 30 ° C a cikin kayan ɗakinta na asali, ba ta hanyar isa ga yara.

1 kwamfutar hannu mai rufe jiki ya ƙunshi:

• abu mai aiki: nateglinide 60 da 120 mg,
• tsofaffi: lactose monohydrate, microcrystalline cellulose, povidone, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide (E171), talc, macrogol, silsilar siliki na anhydrous, ja baƙin ƙarfe oxide (E172).

Zabi ne

Lokacin amfani da Starlix don lura da marasa lafiya da ke da nau'in ciwon sukari na 2 na marasa lafiya (wanda ba shi da insulin) ba, ya kamata a lura da yin taka tsantsan game da abin da ya faru da cutar rashin ƙarfi a cikin jini. Rashin haɗarin haɓakar hypoglycemia yayin ɗaukar Starlix (har ma da sauran magunguna na hypoglycemic) ya fi girma a cikin tsofaffi marasa lafiya tare da rage nauyin jiki a gaban adrenal ko pituitary insufficiency. Rage yawan haɗarin glucose na jini ana iya haifar dashi ta hanyar shan giya, ƙara yawan aiki na jiki, da kuma amfani da wani magani na lokaci guda.

Yin amfani da beta-blockers lokaci guda zai iya rufe alamun bayyanar cututtukan jini.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

Marasa lafiya da ke aiki da injuna da abubuwan tuki ya kamata su yi taka-tsantsan don hana hypoglycemia.

Side effects

Yanayin aiki na iya haifar da bayyanar da sakamakon da ake so:

• Rage tashin hankali da rauni
• Rashin ci
• Da gajiya da farin ciki,
• Karin gumi
• Remarfin wata gabar jiki.

Kwayar cutar ta bayyana a cikin marasa lafiya tare da ƙwayar glucose na ƙasa da 3.4 mmol / L. Haɗe tare da sukari.

Abubuwa na rashin sa'a sune rashes na rashin lafiyar jiki da jan launi na fata, wani lokacin karuwar ayyukan hanta na hanta.

Hulɗa da ƙwayoyi

Starlix yana hana sakamakon tolbutamide.

Nateglinide baya hulɗa tare da abubuwan cytochrome:

• don CYP2C9 - diclofenac,
• don CYPЗА4 da CYP2С9 - warfarin.

Hakanan ba a fallasa shi ga digoxin ba, troglitazone.

Kayan aiki baya tasiri akan aikin metformin da glibenclamide. Beta-blockers na iya rufe alamun bayyanar cututtukan jini.

Yana yiwuwa a cimma haɓaka sakamakon tasirin nateglinide yayin ɗaukar monooxidase inhibitors (MAOs), magungunan anti-mai kumburi steroidal da salicylates. Glucocorticosteroids, hormones na thyroid, sympathomimetics, thiazide diuretics suna rage sakamako. A lokaci guda, dole ne a kula da yawan ƙwayar glucose a hankali.

Ba a buƙatar ƙarin gyara na yau da kullun lokacin amfani da shi tare da kwayoyi waɗanda ke da alaƙa da kariyar plasma (acetylsalicylic acid, captopril, nicardipine, propranolol, furosemide).

Yin amfani da Starlix a lokaci guda tare da wasu magunguna na aikin hypoglycemic na iya haifar da faduwa cikin darajar glucose.

Umarni na musamman

Shan giya da kuma ƙara yawan aiki na jiki na iya haifar da tsotsar jini.

Bayan sa'o'i biyu bayan cin abinci, ana bada shawarar yin gwajin jini don sukari.

MUHIMMIYA! Magungunan yana shafar gudanar da abin hawa, sabili da haka, direbobi da mutanen da sana'arsu ke da alaƙa da gudanar da hanyoyin, dole ne su mai da hankali.

Za'a iya amfani dashi a hade tare da wasu magungunan hypoglycemic - alal misali, metformin. Hakanan, likitan ya cancanci ya rubuta Starlix a matsayin monotherapy.

Kwatanta tare da analogues

"Kwanan nan, na fara shan ruwa mai yawa, ƙishirwa kawai ya mamaye ni, babu dalilin da yasa na fara jin ƙishi, matsi ya tashi. Na karanta game da bayyanar cututtuka, na lura cewa ina da ciwon sukari. Na je wurin likita, an tabbatar da cutar. Sun rubuta Starlix. Magungunan ba su da arha. Na yanke shawara duk da haka in yi aiki kamar yadda likita ya umarta. Kafin shan maganin, sukari na ya kasance 12, yanzu - 7. Hawan jini na ya ragu kadan, na dakatar da itching, babu ƙishirwa. A wata kalma, yanayin ya inganta. Amma mafi mahimmanci shi ne bin tsarin abinci. ”

Kostya 2016-09-15 14:11:37.

Allunan Starlix magani ne mai karfi. Dole ne in sha shi da sukari sama da 10. Ya sauka zuwa 3 ".

Antonina Egorovna 2017-12-11 20:00:08.

"Sun rubuta Maninil a bara. Babu wani sukari mai kyau. Na je wurin wani likita, sun sallami Starlix. Dole ne in sha Allunan 2 na 60 tare da Glucofage da safe da kuma kafin lokacin barci. Ina jin dadi. A karshe dai sukari ya dawo daidai.

Yadda ake amfani: sashi da hanya na jiyya

A ciki, kai tsaye kafin cin abinci (lokacin tsakanin shan magani da cin abinci kada ya wuce minti 30).

Tare da monotherapy, maganin da aka ba da shawarar shine 120 MG 3 sau a rana (kafin karin kumallo, abincin rana da abincin dare). Idan ba zai yiwu a cimma tasirin da ake so ba, ana ƙaruwa da kashi ɗaya zuwa 180 MG.

Gyara hanyoyin yin allura ya dogara ne akan ƙayyadaddun Hb wanda aka ƙayyade akai-akai. Ganin cewa babban tasiri na warkewa shine don rage yawan abubuwan da suka shafi jini a cikin postprandial, yawan kwantar da hankalin glucose na 1-2 sa'o'i bayan cin abincin kuma za'a iya amfani dashi don kimanta ingancin warkewar cutar.

A cikin maganin haɗin gwiwa, ana wajabta nateglinide a kashi na 120 mg sau 3 a rana a hade tare da metformin, idan darajar glycosylated Hb ta kusanto darajar da ake so (ƙasa da 7.5%), ana iya rage kashi zuwa 60 MG sau 3 a rana.

Game da aiki mara kyau ba game da aiki, ba a buƙatar gyaran sashi ba.