Acarbose (Acarbose) > Jiyya da rigakafin

Gasar kuma ta sake hanawa zuwa alt-amylase na pancreatic (hydrolyzes polysaccharides zuwa oligosaccharides) da kuma membrane-daure alpha-glucosidases (rushe oligo-, tri- da disaccharides zuwa glucose da sauran monosaccharides) a cikin lumen karamin hanji. Yana rage samuwar da kuma daukar glucose a cikin hanji, yana rage zubar jini bayan jini, yawan canzawar jini a cikin jini yau da kullun. Ba ya ƙaruwa da haɓakar insulin kuma baya haifar da hypoglycemia.

A cikin karatun gwaji a cikin vitro da a cikin vivo babu shaidar mutagenicity. Gudanarwa da berayen tare da abinci bai shafi haihuwa da kuma ikon haihuwa gaba ɗaya.

Kimanin kashi 35% na kashi mai sarrafawa yana karɓa daga ƙwayar gastrointestinal, mai yiwuwa a cikin hanyar metabolites (wanda 2% yake a cikin aiki), bioavailability shine 1-2%. C_max an cimma shi bayan awa 1, metabolites - bayan sa'o'i 14 zuwa 14 a cikin marasa lafiya da gazawar renal (Cl creatinine 2) C_max yana ƙaruwa sau 5, a cikin tsofaffi - sau 1.5. Yana da metabolized na musamman a cikin narkewa kamar abinci, akasari ta kwayoyin cuta na hanji da kuma narkewa enzymes narkewa, tare da samuwar akalla mahadi 13. An gano babban metabolites azaman asalin abubuwa na 4-methylpyrogallol (a cikin nau'in sulfate, methyl da glucuronic conjugates). Metabolaya daga cikin metabolite, samfurin kayan aikin glucose na acarbose, yana da ikon hana alpha glucosidase. Acarbose wanda ba a iya aiki da shi ba (kusan kashi 51% na kashi) an cire shi da jijiyoyi na awanni 96. Kusan kashi 34% na kashi yana toshe kodan ta hanyar metabolites, kasa da 2% - ba canzawa kuma a cikin yanayin metabolite mai aiki. T_1/2 a cikin lokacin rarrabawa - awa 4, a cikin lokacin shakatawa - awa 10

Yin amfani da sinadarin Acarbose

Nau'in sukari na 2 na ciwon sukari tare da rashin daidaituwa game da tsarin abinci (wanda yakamata ya kasance aƙalla watanni 6) ko kuma isasshen abubuwan da ake buƙata na maganin sinadari mai ƙarancin kuzari, nau'in ciwon sukari na 1 (a matsayin ɓangare na maganin haɗin kai), nau'in rigakafin ciwon sukari na 2 na ciwon sukari (a cikin marasa haƙuri tare da raunin haƙuri glucose a hade tare da abinci da motsa jiki).

Contraindications

Hypersensitivity, mai ciwon sukari ketoacidosis, cirrhosis na hanta, m da na kullum mai kumburi cututtuka, rikitarwa ta narkewa da cuta cuta (ciki har da malabsorption ciwo, maldigestion syndrome), Remkigned ta syndrome, gastrointestinal fili tare da ƙara gas samuwar, ulcerative colitis, na hanji, t .h. m ko predisposition zuwa gare shi, tsaurara da rauni na hanji, hernias mai yawa, gazawar na koda (abun da ke cikin sama da 2 mg / dl), ciki, shayar da nono.

Sakamakon sakamako na abubuwan Acarbose

Daga gefen narkewa kamar: ciwon ciki, rashin jin daɗi, tashin zuciya, zawo, da wuya - karuwa a matakin transaminases (ALT da AST), hanawar hanji, jaundice, hepatitis (a lokuta mafi ƙaranci, mai cikawa tare da mummunan sakamako).

Allergic halayen: fata na fitsari, hyperemia, exanthema, urticaria.

Sauran: da wuya - kumburi.

Haɗa kai

Sakamakon yana rage carbon da sauran adsorbents na hanji, abinci mai narkewar abinci mai narkewa wanda ke dauke da sinadarin pancreatin ko amylase. Thiazide diuretics, corticosteroids, phenothiazines, hormones thyroid, estrogens, gami da su kamar yadda wani bangare na hana hana daukar ciki, phenytoin, nicotinic acid, sympathomimetics, calcium antagonists, isoniazid da sauran kwayoyi waɗanda ke haifar da hyperglycemia, sun raunana takamaiman aikin (yiwuwar lalata cututtukan ƙwaƙwalwar ƙwayar cuta), sulfonylureas, insulin, metformin - inganta tasirin hypoglycemic.

Kariya don abu Acarbose

Wajibi ne a bi tsarin abinci sosai. Ya kamata a ɗauka a cikin zuciya cewa abinci da abin sha waɗanda ke ɗauke da babban adadin carbohydrates, sukari na kara zai iya haifar da rikicewar hanji. Yakamata a gudanar da jiyya a karkashin kulawar matakin glucose a cikin jini da / ko fitsari, glycosylated haemoglobin da transaminases a farkon shekarar magani - sau 1 a cikin watanni 3 sannan kuma lokaci-lokaci. Theara yawan zuwa kashi 300 MG / rana yana haɗuwa tare da ƙarin, amma dan kadan an nuna raguwa a cikin hypglycemia na postprandial tare da haɓaka lokaci guda a cikin hadarin hyperfermentemia (ƙara yawan hankali na AST da ALT a cikin jini). Tare da yin amfani da sulfonylurea ko insulin a lokaci guda, yana yiwuwa a haɓaka hypoglycemia, wanda aka gyara ta ƙara sukari (glucose, amma ba sucrose) ga abinci, ko gabatar da glucose, ko amfani da glucagon (a cikin mawuyacin yanayi). Game da cutar rashin ƙarfi na hypoglycemia, ya kamata a ɗauka a hankali cewa abincin sukari ya zama sannu a hankali ya karye zuwa fructose da glucose yayin magani kuma bai dace da saurin kawar da hypoglycemia ba, a cikin waɗannan yanayin yana da kyau a yi amfani da glucose a cikin manyan allurai.

Form sashi

50 MG da allunan 100 MG

Tabletaya daga cikin kwamfutar hannu ya ƙunshi

abu mai aiki - acarbose 50 ko 100 MG,

tsofaffi: colloidal anhydrous silicon dioxide, magnesium stearate, sitaci masara, celclose microcrystalline.

Allunan daga farare zuwa fari tare da launin shuɗi mai launin shuɗi, zagaye a siffar, tare da zanen "G 50" a gefe ɗaya kuma sanya hannu akan giciye Bayer a ɗaya gefen (don sashi na 50 MG).

Allunan daga farare zuwa fari da launin shuɗi mai launin shuɗi, mai kama da kyan gani, tare da alamar rubutu da zane-zanen "G 100" a gefe ɗaya kuma alama a ɗaya gefen (don sashi na 100 MG).

Kayan magunguna

An yi nazarin magungunan acarbose bayan maganin baka na wani abu mai ɗauke da kayan rediyo mai mahimmanci (200 MG).

Tun da kusan kashi 35% na adadin aikin rediyo (jimlar adadin aiki da metabolites) kodan ya kwantar da shi tsawon awanni 96, ana tsammanin matsayin girman sha yana cikin waɗannan iyakokin.

Plasma jimlar aikin rediyo yana sanannu zuwa kololuwa biyu. Observedan fari na farko, wanda yake daidai da matsakaiciyar yawan acarbose na 52.2 + 15.7 μg / L, ana lura dashi bayan sa'o'i 1.1 + 0.3. Matsakaicin mafi girma na biyu shine 586.3 + 282.7 μg / L kuma ana lura dashi bayan sa'o'i 20.7 + 5.2. Ba kamar ɗaukar rediyo ba gaba ɗaya, matsakaicin ƙwayar abu mai hanawa cikin plasma shine sau 10-20. Bayyanar girman ganiya ta biyu bayan kimanin awanni 14 zuwa 14 a bayyane yake saboda ɗaukar abubuwan lalata na ƙwayoyin cuta daga ɓangarorin zurfin ƙananan hanji.

A bioavailability na miyagun ƙwayoyi ne kawai 1-2%. Wannan ƙarancin ƙananan yawan tsararren tsari yana da kyawawa saboda acarbose yana aiki ne kawai a matakin hanji. Saboda haka, ƙarancin bioavailability na miyagun ƙwayoyi ba ya shafar tasirin warkewa.

Distributionararren rarraba raba shine 0.32 l / kg nauyin jiki.

Rage rabin rayuwar don rarrabawa da kuma share fage shine 3.7 + 2.7 hours da 9.6 + 4.4 hours, bi da bi, 51% na abu mai aiki ana fesawa cikin hanjin cikin awa 96, 1.7% ba canzawa kuma kamar aiki metabolite - ta hanyar kodan.

Abubuwan da ke aiki na miyagun ƙwayoyi Glucobay ac - acarbose shine asalin pseudotetrasaccharide asalin microbial. Ana iya amfani da Glucobay® don magance duka insulin-dogara da insulin-mai ciwon sukari mai zaman kanta mellitus.

Acarbose yana aiki a matakin ƙwayar gastrointestinal, yana hana ayyukan ƙananan enzymes na hanji (alpha-glucosidase), waɗanda ke shiga cikin rushewar di-, oligo- da polysaccharides. Sakamakon haka, jinkirin da ya dogara da shi a cikin narkewar carbohydrates yana faruwa, yana biye da jinkirin sakewa da kuma ɗaukar glucose, wanda aka kirkira yayin rushewar carbohydrates. Don haka, acarbose yana jinkirta kuma yana rage haɓakar postprandial a cikin tattarawar glucose a cikin jini. Sakamakon ɗaukar daidaituwa na glucose daga hanji, matsakaiciyar ƙwayar glucose da sauyin yanayin yau da kullun cikin jini yana raguwa. Game da haɓaka haɗuwa da glycosylated haemoglobin, acarbose yana rage matakinsa.

A cikin gwaje-gwajen da ba a tsara ba, an gano cewa a cikin marasa lafiya da ke da tabbacin raunin glucose, gudanarwar yau da kullun na Glucobaya® yana rage haɗarin haɗarin kamuwa da ciwon sukari na 2. Bugu da kari, an gano cewa a lokaci guda sun rage yawan aukuwar abubuwan da ke faruwa na zuciya da jijiyoyin jini.

Amfani da Glucobaya® don ciwon sukari na 2 yana rage haɗarin haɓakar cututtukan zuciya da ƙananan cututtukan zuciya.

Alamu don amfani

- lura da ciwon sukari ban da maganin rage cin abinci

- rigakafin kamuwa da ciwon sukari na 2 a cikin marasa lafiya tare da tabbacin rashin haƙuri na glucose * tare da abinci da motsa jiki

* an bayyana shi azaman ƙwayar glucose na plasma 2 sa'o'i bayan nauyin glucose na 7.8-11 mmol / l (140-200 mg / dl) da kuma matakan glucose na azumi na 5.6 - 7.0 mmol / l (100-125 mg / dl )

Sashi da gudanarwa

An zaɓi kashi na miyagun ƙwayoyi ne ta hanyar halartar likitocin daban-daban ga kowane mai haƙuri, tun da ingancinsa da haƙurinsa sun bambanta.

Allunan Glucobaya® suna da tasiri ne kawai idan an sha su kai tsaye kafin abinci gabaɗaya, ba tare da taunawa ba, tare da ɗan adadin ruwa, ko tauna tare da abincin farko.

Jiyya don ciwon sukari ban da abinci

Sai dai in an kayyade in ba haka ba, ana bada shawarar waɗannan allurai:

Maganin farko shine 1 kwamfutar hannu na 50 MG sau 3 a rana tare da kowane babban abinci ko ½ kwamfutar hannu na 100 MG sau 3 a rana tare da kowane babban abinci. A nan gaba, yakamata a kara adadin zuwa matsakaita na yau da kullum na 300 MG kowace rana (2 Allunan 50 na 50 sau 3 a rana tare da kowane babban abinci ko 1 kwamfutar hannu 1 na 100 mg sau 3 a rana tare da kowane babban abincin).

A wasu halaye, idan ya cancanta, ana iya ƙara yawan ƙwayar zuwa 200 mg sau 3 a rana tare da kowane babban abinci.

Za'a iya ƙaruwa kashi ɗaya bayan makonni 4-8 idan ba a samo sakamako na asibiti da ya cancanta ba a cikin marasa lafiya a kashi na baya.

Idan mai haƙuri, duk da tsananin kulawa da abincin, ƙoshin lafiya da gudawa na ƙaruwa, to ya kamata a dakatar da ƙarin karuwar kashi na ƙwayar, kuma a wasu halayen an rage kashi.

Matsakaicin maganin yau da kullun shine 300 MG kowace rana.

Yin rigakafin kamuwa da ciwon sukari na 2 a cikin marasa lafiya da ke fama da rashin haƙuri a cikin haɗuwa tare da abinci da motsa jiki

Maganin farko shine 50 MG sau ɗaya a rana (Allunan 50m ko Allunan kwayoyi once 100 sau ɗaya a rana). A cikin watanni 3, ana fara samun kashi na farko zuwa shawarar warkewar magani na 100 mg sau 3 a rana (Allunan 2 na 50 MG ko kwamfutar hannu 1 na 100 MG sau uku a rana tare da kowane babban abinci).

Ba a bukatar canji a kashi ko tsarin allurai ba.

Marasa lafiya tare da nakasa aikin hanta

A cikin marasa lafiya da ke fama da aikin hanta, ba a buƙatar canza canji a tsarin aikin.

Babu hani akan jimlar shan Glucobay®.

Ku ci kuma ku rasa nauyi

Wannan shine babban matsalar. Recommendationsarancin shawarwari kamar iyakance mai ƙima da haɓaka adadin kayan lambu, kifin dafaffen hatsi da hatsi a cikin abincin ba su dace da mutane ba. A matsayinka na mai mulki, mutum yana son cin abin da ke ba da mafi jin daɗi, ɗanɗano mai ɗanɗano. Kuma yayin da ba wai kawai samun nauyi ba, amma kuma rabu da mu tara. Abin baƙin ciki, babu mu'ujizai a cikin duniya. Idan kun cinye adadin kuzari fiye da abin da kuka ciyar, za'a ajiye su a gefuna.

Amma wannan dokar ba a bayyane take ga kowa ba. In ba haka ba, yadda za a bayyana saurin saurin furanni daban-daban na fats da carbohydrates? Talla na yi mana alƙawarin cewa za ku iya jin daɗin abincin da kuka fi so, kawai bayan ɗaukar kwaya. Kuma duk abin da aka ci zai bar jiki ba tare da lahani ba. Shin haka ne - bari mu tsara shi tare.

Duk hanyoyin suna da kyau

Abu ne mai sauqi kazo ga wannan matsayar, ya isa ka yi la’akari da kasuwar magungunan zamani don rage nauyi. Daga cikinsu akwai kwayoyi har ma da magungunan kashe qwari, magungunan hormonal. Kwanan nan, wani magani wanda aka yi niyya don maganin marasa lafiya da ciwon sukari ya fara samun karbuwa. Ana amfani dashi don asarar nauyi "Acarbose". Nazarin wadanda suka gwada maganin sun sha bamban da juna, wasunsu ma ba su da kyau. A'a, mutane sun rasa nauyi kwarai da gaske, amma tasirin sakamako irin wannan ne sakamakon da aka samu ba mai dadi bane. Don kowa ya sami damar yin tunani game da sakamakon, a yau za mu yi la’akari da siffofin wannan magani, dalilinsa da tasirinsa ga jiki.

Ba panacea ba

Babban mummunan maƙiyi na adadi kyakkyawa shine Sweets. Yana da matukar wahala a ƙi mashaya ko kukis, kek ko kayan zaki. Sabili da haka, jiki yana karɓar ƙwayoyin carbohydrates mai yawa. Tabbas, ba ku da ikon ciyar da su, sai dai idan kuna aiki a zahiri a wuraren da ake yin gini.

Abin da ya sa aka jawo hankalin mata ga magungunan da za su iya toshe sinadarai masu sauki, saboda ana iya amfani dasu don asarar nauyi. Akwai daban-daban nazarce-nazar game da “Acarbose”, amma ya kamata koyaushe ku tuna cewa an samar da wannan magani ne domin samar da taimakon da yakamata ga masu ciwon sukari. Rage nauyi shine sakamakon sa.

Abu mai aiki

Ba tare da takardar likita ba, kusan kusan ba zai yiwu ba ne ka saya. Tabbas, ba zai yiwu ba cewa zaku iya shawo kan endocrinologist cewa kuna buƙatar shi don gyara lahani na jikin mutum. Wannan samfurin likita ne, amfanin abin da dole ne ya barata. Bugu da kari, tare da haɗin gwiwa na amfani da "Acarbose" da sauran magunguna, tasirin sakamako na iya ƙaruwa.

Abunda ke aiki shine acarbose, mai hana alpha-glucosidase, enzyme na pancreas. Yana lalata hadaddun sugars zuwa glucose da fructose. Bari mu tsaya anan kadan, saboda yana da mahimmanci a fahimci yadda kwayar take aiki kuma me yasa "Acarbose" ke taimakawa rage nauyi. Nazarin likitoci ba masu kyakkyawan fata bane, kawai basu bayar da shawarar yin gwaji tare da lafiyarsu ba.

Don haka, inhibitor na alpha glucosidase yana hana narkewar abinci da kuma karɓar carbohydrates a cikin ƙananan hanji. Sabili da haka, haɓakar glucose na jini ya ragu bayan cinye abubuwan da ke dauke da carbohydrate. Sakamakon haka, jikinka yana samun ƙasa da adadin kuzari, wanda ya haifar da asarar nauyi a hankali.

Don m hakori

Wannan rukuni na mutane ne waɗanda yawancin lokuta ke gwada tasirin waɗannan kwayoyi akan kansu. A kowane hali, ana tabbatar da hakan ta hanyar bita. "Acarbose" don asarar nauyi da alama sun dace. Yanzu ba za ku iya tsayar da adadi mai karko ba. Yi farin ciki da abincin da kuka fi so ba tare da tsoron samun ƙarin santimita a kwatangwalo da kugu ba.

A lokaci guda, mutane da yawa za su yi tambaya: yaya jikin zai yi ba tare da carbohydrates? Ko da ga lafiyayyen mutum, wannan ya cika da manyan matsaloli, kuma idan muka yi magana game da marasa lafiya da ciwon sukari mellitus, har ila yau za su iya shiga cikin kwayar cuta daga matsananciyar ƙwayar carbohydrate. Maƙerin ya ce cutarwar ƙwayar cutar ƙwaƙwalwa ta iyakance. Wato, baya samun damar rage sukarin jini a kasa mai mahimmanci.

Abubuwan farko

Yanzu bari mu kalli yadda wannan kayan aiki yake aiki a zahiri. Amfaninta masu amfani kamar haka:

Magungunan kusan kusan yana toshe ɗaukar abubuwan carbohydrates masu shigowa, ban da ƙaramin adadinsu. A sakamakon haka, nauyin yana farawa da sauri. Yayi daidai da guda ɗaya idan kun daina sukari, gurasa, kankara da kayan abincin.
Wannan tsari baya tasiri ga yawan ƙwayar tsoka, tunda furotin da ke shiga jiki yana cikin damuwa ba tare da wata matsala ba.
Magungunan yana rage ci, saboda haka aiwatar da asarar nauyi zai zama mawuyaci.

Ya kamata a lura cewa ba kawai "Acarbose" ba, har ma da sauran magungunan cututtukan jini suna da tasirin sakamako ɗaya. Tare da ciwon sukari, marasa lafiya suna iyakance yawan cin abincinsu, abubuwan cin abinci da burodi, don haka babu matsaloli tare da shan magunguna. Amma mutum talakawa bai saba da waɗannan ƙa'idodin ba kuma ya ci gaba da karin kumallo tare da shayi mai daɗi tare da madara, yi ko kukis. Me zai faru sakamakon hakan? A cikin hanjin akwai matsanancin ƙwayoyin carbohydrates, babu wani abin da zai rushe su, mummunan rauni, zafi da kwaɗaitar zuwa ɗakin bayan gida. Ba sa so ka ɗanɗana irin wannan ji? Guji maɓallan carbohydrates, banda hatsi na hatsi gaba ɗaya a cikin matsakaici. Sannan ba a buƙatar magungunan hypoglycemic. Tasirin zai zo da kanshi.

Waɗannan shawarwari ne na yawancin likitoci, masana ilimin abinci da kuma maganin cututtukan dabbobi. Babu buƙatar ɗaukar magani wanda a bayyane yake don wasu dalilai. Amma ba shakka, mata suna dagewa sosai. Kuma idan kun yanke shawarar amfani da "Acarbose" / analogues na wannan miyagun ƙwayoyi, baza su daina ba. Da kyau, kyakkyawa na bukatar sadaukarwa. Amma shin irin waɗannan waɗanda abin ya shafa suna cikin irin wannan sanannen faɗin? Dole ne mutum yayi tunanin sakamakon irin wannan matakin.

Abin da ya kamata ku sani game da

Yawanci, haƙuri ba ya buƙatar yin nazarin abun da ke tsakanin miyagun ƙwayoyi kuma zaɓi sashi, idan likita ya ba da shawarwari kuma ya tsara lokacin aikin. Amma idan ka yanke shawarar ɗaukar shi da kanka, tabbatar da karanta umarnin don amfani. Ana amfani da "Acarbose" don nau'in ciwon sukari na 2 tare da rashin ingancin maganin abinci. Haka kuma, tsawon lokacin daya kamata ya kasance akalla watanni 6. Hakanan ana wajabta wakili a zaman wani ɓangaren hadadden farke don cututtukan type 1.

Side effects

Wannan lamari ne mai ciwo, saboda jerin "sakamako masu illa" yana da ban sha'awa sosai. Amma mafi yawan maganin aspirin da ba a iya amfani da shi ba za a iya kiranta lafiya gaba ɗaya. Ana amfani da wadannan abubuwan da suka biyo baya a cikin umarnin:

Rashin lafiyar jijiyoyin jiki
Allergic halayen.
Matsaloli a cikin narkewa. Hakan shine rashin jin daɗi, gudawa, tashin zuciya.
Amsawa daga hanta. Waɗannan na iya zama ƙananan lamuran da ba su shafar lafiyar kirki. Amma ci gaban jaundice shima zai yiwu.

Zai zama da amfani don sanin kanka tare da sake dubawa game da shan miyagun ƙwayoyi. Ana amfani da "Acarbose" don asarar nauyi, duk da dukkanin gargadin da masanan ke bayarwa. A zahiri, akwai mutane da yawa waɗanda ba su taɓa samun wata illa ba kuma sun gamsu da sakamakon maganin. Wasu bita sun kira shi mafi aminci ga jiki fiye da Xenical, wanda kuma yana iya haifar da raɗaɗi mai raɗaɗi, musamman, idan mutum yana son abinci mai ƙima.

Kwarewa mai amfani

Mafi yawan lokuta, kamar haka daga umarnin, halayen marasa kyau sune matsaloli tare da ƙwayar gastrointestinal. Amma akwai mutanen da ba dozainin dozin ba waɗanda ke yanke shawara don gwada tasirin mu'ujiza kan kansu. A farashin "Acarbose" yana samuwa, wannan shine ƙarin dalili don gwada wannan magani. Sakamakon haka, ga wasu asarar nauyi komai yana da kyau har suna ɗaukar shi na watanni da yawa a jere, a lokaci guda suna jin daɗin kansu da Sweets kuma sun rasa gramsan kilo. Abin takaici, ba kowa bane ke da sa'a.

Dole ne a tuna cewa ita jarabawa ce ta gaske, wacce ke nuna yawan ɗarukan carbohydrates. Amma haka ne, kuma a kwanaki masu zuwa mutane sun yarda da hakan. Idan abincin ya daidaita, to babu rashin kwanciyar hankali.

Banda za a iya ɗauka zawo ko amai a cikin kwanakin farko na 2-3 na shan maganin. Amma yana da daraja ƙara yawan zaki, a matsayin "yaƙi" yana farawa a ciki. Sensations, yin hukunci ta hanyar sake dubawa na masu fama, ba su da daɗi: mara lafiya, murguda baki, yankan, jita-jita da iska.

Hanyar fita

Mun riga mun bincika tsarin aikin Acarbose. Carbohydrates yana tarawa cikin hanji, saboda ba za su iya rarrabewa ba kuma sun sha. A can suke yawo, wanda ke haifar da irin wannan sakamako. Saboda haka, zamu iya cewa miyagun ƙwayoyi shima yana da aikin koyarwa. Yana koyar da ku da ku ɗanɗano kayan lefe kawai a gida da kuma a ƙarshen mako. Wannan a cikin kanta yana da kyau. Kuma idan ya fara "hanzarta", to, za mu cire dukkanin carbohydrates, gami da burodi da hatsi, na awa 4-6 - kuma komai ya wuce. Don haka mutane suna rubutu a cikin sake duba su. Amma yana da daraja rasa nauyi ta wannan hanyar? Bala'i a cikin jiki na wasu lokuta ba zai zama mai jujjuyawa ba.

Tsarin aiki da umarnin don amfani da Acarbose Glucobay

Shekaru da yawa ba tare da gwagwarmaya ba game da IYAYE?

Shugaban Cibiyar: “Za ku yi mamakin yadda sauƙin sauƙin magance ciwon sukari ta hanyar shan shi kowace rana.

Saboda rashi na yau da kullun na insulin hormone, mummunan cuta na tsarin endocrine yana haɓaka jikin mutum - ciwon sukari mellitus.

Ingancin mutane da wannan ilimin yana da alaƙa ta hanyar magungunan hypoglycemic waɗanda ke tsara matakan glucose. Acarbose magani ne mai inganci na maganin cututtukan cututtukan cututtukan fata.

Alamu don alƙawari

An rubuta maganin ta hanyar endocrinologist idan akwai cututtukan da ke gaba:

type 2 ciwon sukari mellitus,
wuce haddi abun ciki a cikin jini da kyallen takarda na lactic acid (lactic diabetic coma).

Bugu da ƙari, a hade tare da abincin abinci, ana nuna magungunan don nau'in ciwon sukari na 1 na mellitus.

Ba a yarda da amfani da miyagun ƙwayoyi ba idan mai haƙuri yana da cututtukan masu haɗawa masu zuwa:

rashin haƙuri,
m rikitarwa na ciwon sukari (ciwon sukari ketoacidosis ko DKA),
wanda ba a canzawa ba na ƙwayar hanta (cirrhosis),
mai wahala da raɗaɗi narkewa (dyspepsia) na yanayin rayuwa,
canje-canje na aikin zuciya wanda ke faruwa bayan cin abinci (Raunin Remkighter's syndrome),
lokacin haihuwa da shayarwa,
kara gas a cikin hanjin,
na kullum mai kumburi cuta na mucous membrane na ciwon (ulcerative colitis),
protrusion na gabobin ciki a karkashin fata (ventral hernia).

Abun ciki da tsarin aiwatarwa

Acarbose (sunan Latin Acarbosum) shine carbohydrate na polymeric wanda ke dauke da karamin adadin sukari mai sauki, mai sauƙin narkewa cikin ruwa.

Maganin yana haɓaka ta hanyar sarrafa kwayar halitta a ƙarƙashin tasirin enzymes. Man albarkatun shine Actinoplanes utahensis.

Acarbose hydrolyzes polymeric carbohydrates ta hanyar hana enzyme dauki. Don haka, matakin samuwar abu da kuma yawan kuzarin sukari a cikin hanji yana raguwa.

Wannan yana taimakawa wajen tsaida matakan glucose na jini. Magungunan ba ya kunna samarwa da ɓoye ƙwayar insulin ta hanyar ƙwayar ƙwayar cuta kuma baya bada izinin raguwa mai yawa a cikin sukarin jini. Magunguna na yau da kullun yana rage yiwuwar ciwan cututtukan zuciya, da ci gaban ciwon sukari.

Shaye shaye (mamaye) bai wuce 35% ba. Cakudewar wani abu a jiki yana faruwa ne a matakai: ɗaukar farko tana faruwa ne a cikin sa'o'i ɗaya da rabi, sakandare (ɗaukar samfuran abubuwa) - a cikin kewayon daga sa'o'i 14 zuwa rana guda.

Tare da ciwo na cikakkiyar aikin ƙwayar cuta na kodan (gazawar koda), yawan ƙwayar miyagun ƙwayoyi yana ƙaruwa sau biyar, a cikin mutane masu shekaru 60 + 1.5 sau.

Ana cire miyagun ƙwayoyi daga jiki ta hanyar hanji da tsarin urinary. Lokacin tazara na wannan tsari na iya zuwa awa 10-12.

Umarnin don amfani

Yin amfani da acarbose ya ƙunshi dogon jiyya. Allunan ya kamata a bugu a kalla kwata na awa daya kafin cin abinci.

A cikin farkon magani, an tsara 50 mg na miyagun ƙwayoyi sau uku a rana. In babu halayen da ba su da kyau, ana karuwar kashi 2 zuwa 2 tare da tazara tsakanin watanni 1-2.

Matsakaicin adadin guda ɗaya shine 200 MG, kullun - 600 MG.

Don dalilai na prophylactic, ana ɗaukar miyagun ƙwayoyi a cikin mafi ƙarancin iya zubar (50 MG) sau ɗaya a rana. Dangane da alamu, ana iya ninka adadin zuwa ninki biyu.

Shin Acarbose Glucobai za a iya amfani dashi don asarar nauyi?

Magungunan da aka fi amfani da su a kan tushen Acarbose shine magungunan Glucobay na Jamusanci. Tasirin sa na magunguna, alamomi da kuma contraindications don amfani iri ɗaya ne ga Acarbose. Koyaya, yin amfani da miyagun ƙwayoyi bai iyakance ga lura da ciwon sukari ba.

Glyukobay ya shahara sosai tsakanin athletesan wasa da mutanen da ke fama da kiba. Wannan shi ne saboda babban tasirin maganin - ikon toshewa da samuwar glucose. Dalilin wuce haddi mai nauyi, a matsayinka na mai mulki, shine yawan adadin carbohydrates. A lokaci guda, carbohydrates sune asalin tushen albarkatun makamashi na jiki.

Lokacin hulɗa tare da gabobin narkewa, ƙananan carbohydrates suna ɗauka nan da nan hanjinsu, carbohydrates masu rikitarwa suna shiga cikin matakan lalata zuwa cikin sauki. Bayan shaye-shaye ya faru, jiki yana neman shan abubuwan kuma ya ajiye shi “a ajiye”. Don hana waɗannan hanyoyin, waɗanda suke so su rasa nauyi suna ɗaukar Glucobai azaman wakilin mai toshe ƙwayoyin carbohydrate.

Abubuwan bidiyo game da kwayoyi masu hana karba a jiki:

Side effects, yawan abin sama da ya kamata da kuma umarnin musamman

Sakamakon maras amfani yayin gudanar da miyagun ƙwayoyi yana faruwa ne musamman daga epidermis da ƙwayar gastrointestinal.

Wadannan sun hada da:

rashin tsoro
haushi
zafi narkewa (dyspepsia),
wahalar inganta abinda ke ciki na narkewa (hanjin hanji),
matsakaicin matakin bilirubin (jaundice),
jan launi na fata wanda ya haifar da yaduwar capillaries (erythema),
rashin lafiyan epidermal.

Fiye da maganin da aka tsara an bayyana shi ta hanyar ciwon hanji, haɓakar iskar gas, zawo. Da sauƙin wannan yanayin alamu ne, tare da warewar kayan abinci na carbohydrate daga abinci.

An wajabta maganin Acarbose tare da taka tsantsan ga marasa lafiya da cututtukan cututtukan-hoto, da kuma matasa masu shekaru 18 da haihuwa.

A lokacin maganin ƙwayar cuta, babban yanayin shine:

bin tsaftataccen abinci
ci gaba da lura da cutar haemoglobin, transaminases da sukari (ƙididdigar jini).

A cikin abinci, ya kamata a maye gurbin sucrose tare da glucose.

Analogues na miyagun ƙwayoyi

Magunguna suna da irin wannan tasiri suna ɗaukar acarbose a matsayin babban abu mai aiki.

Ana amfani da magunguna biyu azaman madadin:

Glucobay50 nau'i na 50 kwamfutar hannu fomBAYER PHARMA, AG (Jamus) AluminaAllunan 100 MG“Abdi Ibrahim Ilach Sanay ve Tijaret A.Sh.” (Turkey)

Ra'ayoyin masu haƙuri

Daga nazarin masu haƙuri, ana iya ƙarasa da cewa Acarbose yana aiki sosai cikin sharuddan riƙe ƙanƙan jini, amma gudanarwarsa yawanci yana haɗuwa da sakamako masu illa mara kyau, don haka amfani da shi ba shi da mahimmanci don rage nauyi.

Don lura da gidajen abinci, masu karatunmu sunyi nasarar amfani da DiabeNot. Ganin shahararrun kayan wannan samfurin, mun yanke shawarar ba da shi ga hankalin ku.

An gudanar da maganin kamar yadda likitan ya umurce shi kuma yayi daidai da umarnin. Bugu da ƙari, Na ɗauki 4 MG na NovoNorm a lokacin abincin rana. Tare da taimakon magunguna biyu, yana yiwuwa a ci gaba da sukari na yamma. Acarbose “quenches” sakamakon hadaddun carbohydrates, manuniyata sa'o'i biyu bayan cin abinci shine 6.5-7.5 mmol / L. A baya, ƙasa da 9-10 mmol / L bai kasance ba. Magungunan gaske yana aiki.

Ina da ciwon sukari na 2 Likitan ya ba da shawarar Glucobai. Allunan basa bada izinin glucose din a cikin gastrointestinal tract, saboda haka, matakin sukari “baya tsalle”. A halin da nake ciki, miyagun ƙwayoyi sun daidaita sukari zuwa ga mafi ƙarancin alama ga masu ciwon sukari.

Na gwada Glucobai a matsayin wata hanya don rage nauyi. Azabtar da sakamako masu illa. Ciwon zawo, da rauni. Idan baku sha wahala daga ciwon sukari, manta game da wannan magani kuma kuyi asara tare da taimakon abinci da abubuwan motsa jiki.

Magungunan magani ne. Farashin allunan Glucobai kusan 560 rubles ne don guda 30, tare da sashi na 100 MG.

Sabuwar Jiyya Na 2 Magunguna na Ciwon Mara

Marasa lafiya wanda aka wajabta masa magani don nau'in ciwon sukari na 2, an zaɓi magunguna ta hanyar da aka haɗu. Yawan cin abincinsu ba ya tsayawa a duk rayuwarsu. Gaskiya ne, an fara yin tsarin abinci. Kuma kawai to, idan da bukatar taso, shi ne far da kwayoyi da za'ayi. Ana iya bayanin wannan ta hanyar gaskiyar cewa godiya ga abinci mai gina jiki, ana iya kiyaye matakan glucose na al'ada. Don haka babu buƙatar shirye-shiryen insulin. Yana bayyana lokacin da Pathology ya fara ƙaruwa.

Siffofin amfani da magunguna

Cutar ana saninsa da ci gaba a hankali. Da farko dai, alamominsa ana bayyana masu rauni sosai. Saboda haka, rashin alheri, mutane da yawa suna juya zuwa ga likitoci lokacin da rikice-rikice suka taso. Idan ba'a kula da cutar na dogon lokaci ba, to lalata zai iya zama mai sauri.

Tushen maganin cutar siga shine amfani da magunguna. Kwayoyi masu ciwon sukari suna zuwa cikin kungiyoyi da yawa.

Farfesa ya kamata:

Kunna samarda insulin.
Sensara ƙwaƙwalwar ƙwayar nama zuwa hormone.
A hana shan glucose kuma a rage gluconeogenesis, wato, hadinsa.
Gyara matakan ɓataccen yanki na jini.

A takaice, tare da taimakon magani yakamata ku tsayar da iko na rayuwa wanda zai hana rikice-rikice.

Babban rukuni na magunguna don ciwon sukari na 2 ya ƙunshi:

Magunguna, saboda wanda, ƙwayar ƙwayar cuta ta samar da mafi kyawun insulin. Muna magana ne game da shirye-shiryen sulfonylurea waɗanda suke da tsari mai kama da sunadarai kuma sun bambanta daga ƙarni. Kwanan nan, sababbin magunguna, Novonorm da Starlix, sun kuma bayyana.
Biguanides, dalilin shine don kara yawan yiwuwar salula a cikin kwayoyin. Shahararrun guda biyu sun dogara da metformin (Siofor, Glucofage). An wajabta su ga mutane masu kiba, saboda suna taimakawa ragewa.
Alfa glucosidase inhibitors. Rage shan glucose. Sau da yawa ana amfani da magani "Glucobay."
Abun hankali Godiya garesu, amsawar kyallen takarda ga kwayar halitta. Bayyanar da masu karɓar sel galibi ana yinsu ta amfani da Actos.

A cikin rukuni daban akwai magungunan antihypertensive wadanda aka wajabta masu ciwon sukari na 2. Suna buƙatar, lokacin da akwai rikitarwa na yanayin jijiyoyin bugun gini. Yawancin jini ana yin shi ne ta hanyar diuretics thiazide, haka kuma masu amfani da alli na alli (masu amfani da alli).

Magungunan ƙwayar insulin

Daga cikin magungunan, thiazolidinediones da biguanides ya kamata a rarrabe su. Kowace kungiya tana da nasa fa'ida.

Ana amfani da magungunan ciwon sukari na 2, irin su thiazolidinediones don:

rage girman haɗarin da ke haifar da matsaloli tare da tasoshin jini,
sugar sugar,
Kwayoyin cututtukan fitsari
dalilai na m da warkewa.

Abin takaici, su ma suna da aibi.

Thiazolidinedione far na iya haifar da:

bayyanar karin fam,
kumburi daga cikin ƙananan ƙarshen,
osteoporosis.

Don cimma sakamako mafi ƙaranci ko ƙasa da haka, dole ne a ɗauki kuɗi na dogon lokaci. Bugu da kari, akwai hani akan amfanin su.

Jerin marasa lafiyar da aka haramta daga irin wadannan magunguna sun hada da mata masu juna biyu da masu shayarwa, da kuma mutanen da ke fama da cutar:

cututtukan hanta na hanta
bugun zuciya
cututtukan zuciya da jijiyoyin jini.

Ba za ku iya haɗaka lokaci guda tare da insulin da thiazolidinediones ba.

Hakanan ana lura da kyakkyawan sakamako na warkewa daga amfani da biguanides.

ana samun ci gaba a cikin abubuwan da ke cikin jini, yayin da ake rage yawan kwalasta,
hawan jini
haɗarin bugun zuciya a cikin marasa lafiya da ke fama da matsanancin nauyi yana ragewa kaɗan.

Biguanides baya haifar da kiba. Kodayake, lokacin amfani da su, mai haƙuri na iya yin gunaguni na jin rashin jin daɗi a cikin jijiyoyin.

gazawar hanta
shan giya
haihuwar ɗa.

Likitoci sun gwammace yin amfani da magunguna masu zuwa don magani: Siofor, Glyukofazh, Metfogamma.

Hormone kira na motsa ƙwayoyi

An kunna aikin Pancreatic tare da taimakon abubuwan samo asali na sulfonylurea da meglitinides. Zaɓin farko shine magunguna, sakamakon abin da ake jin kusan nan da nan. Godiya ga su, rikicewar jijiyoyin jiki yakan faru sau da yawa. Yawancin lokaci ana rubuta su ne "Diabeton MV", "Maninil." A wasu halaye, an hana yin jiyya tare da abubuwan da ake amfani da su na sulfonylurea.

marasa lafiya da gazawar koda ko ketoacidosis,
mai ciki
mata masu shayarwa.

Kodayake maganin yana ba da sakamako mai sauri, yana yiwuwa:

hawan jini,
ci gaban juriya
kiba.

Amma game da meglitinides, ana iya amfani dasu don kiyaye matakan sukari a matakin da ya dace. Suna kuma da tasirin hanzari. Mafi yawan lokuta, ana nada NovoNorm da Starlix.

Hakanan akwai kasala. Da fari dai, nauyin jikin yana iya ƙaruwa. Abu na biyu, har yanzu ba a tabbatar da cewa tare da tsawan amfani ba, tasirin meglitinides ya ragu.

Dukkanin magungunan da ke sama zasu iya haifar da bugun zuciya, bugun jini da ƙwayar cutar glycemic coma. Sabili da haka, a cikin 'yan shekarun nan, yawancin likitoci sun ƙi waɗannan kudade, suna maye gurbinsu da sababbin magunguna.

Siofor da Glyukofazh

Ga masu ciwon sukari, wadannan kwayoyi sun dogara da metformin. Idan bayyanar cututtuka na nau'in ciwon sukari na 2 ya faru a farkon matakin, idan abincin mai haƙuri yana da ƙananan carbohydrate, kuma zai dauki metformin a kai a kai, to ba za a buƙaci ƙarin magunguna da injections na hormone ba.

"Siofor" an nuna shi ba kawai ga masu ciwon sukari ba, har ma ga duk wanda ke da rikice rikicewar systolic da diastolic pressure. Kwayoyin suna taimakawa wajen daidaita rayuwar mace da dawo da haihuwa.

Marasa lafiya bayan shekaru 65, da kuma waɗanda ke fuskantar matsanancin motsa jiki na yau da kullun, ya kamata a tsara Siofor a hankali (lactic acidosis, wanda ke haɗuwa da karuwar acidity, ba a yanke hukunci ba).

Don haɓaka aikin Siofor, endocrinologists suna ba da shawarar sababbin magunguna - glucagon-like peptide-1 receptor agonists (GLP-1) da dipeptyl peptidase-4 (DPP-4) inhibitors.

A farkon magana, magani ne wanda ya ƙunshi hormone wanda ke rage cin abinci da kuma ƙarfafa haɓakar samar da insulin. Akwai shi a cikin nau'in alkalami na sirinji. Ya kamata a yi allurar sa'a daya kafin abinci. Hanyar guda ɗaya ta isa kwana ɗaya.

Zaɓin na biyu wani nau'in magani ne wanda ya ƙunshi enzyme wanda ke aiki mai lalata akan GLP-1. A shawarar da aka bada shawarar shine kwamfutar hannu 1 a cikin yini.

Kyakkyawan halayen "Glucophage":

Rage sha na carbohydrates a cikin gastrointestinal fili.
Rage ayyukan glucose ta hanta.
Sensara ƙwaƙwalwar insulin.
Inganta tsarin fitarwar sukari ta sel.

A cikin ƙananan adadin marasa lafiya daga shan metformin, bayyanannun bayyanannun yana yiwuwa a cikin hanyar:

tashin zuciya
ƙarfe ɗanɗano a cikin rami na bakin,

yi amai,
colic na hanji
matsanancin tara gas a cikin hanjin,
zawo.

Don kauce wa irin wannan halayen, an kirkiro magunguna masu amfani da tsayi don nau'in ciwon sukari na 2 wanda ba sa haifar da sakamako. Labari ne game da Glucofage Long.

Ana ɗaukar capsules sau ɗaya a rana. A sakamakon haka, ana samar da metformin a hankali kuma a ci gaba. Babu wani farkon spasmodic karuwa a cikin taro taro.

Ya kamata a faɗi dabam game da shari'o'in inda Siofor da Glucophage suka saba.

Guji daga magani tare da waɗannan wakilan wajibi ne lokacin da:

Rashin gazawa kamar hepatic.
Hypoxia na tsarin zuciya da jijiyoyin jini ko na numfashi.
Cutar zuciya, angina pectoris, cardiac arrhythmias.
Matsaloli tare da kewaya kwakwalwa.
Rashin wahala da damuwa.
Cutar mai saurin kamuwa.

Raunin da ya faru.
Rashin baƙin ƙarfe da folic acid.
Al'adar fata.
Ciki

A cikin bayan aikin, an kuma haramta irin wadannan magungunan.

Daidaitattun kudaden

Yawanci, don nau'in ciwon sukari na 2, ana ba da magani tare da magani ɗaya. Amma lokacin da ilimin bai kawo sakamakon da ake so ba, ya zama dole don a ƙara amfani da wasu magunguna. Sau da yawa, maganin da aka zaɓa ba zai iya magance duk matsalolin da ke faruwa ba. Sabili da haka, an maye gurbin shi da wakili mai haɗuwa.

Kuna iya bi da irin waɗannan magunguna ba tare da haɗarin kowane sakamako ba. Mafi sau da yawa, likitoci suna haɗuwa da haɗarin thiazolidinediones da metformin, da kuma abubuwan da aka samo na sulfonylurea da kuma metformin iri ɗaya.

An haɗaka magungunan masu ciwon sukari don hana ci gaba da hauhawar jini. A sakamakon haka, buƙatar insulin therapy ta ɓace.

Shahararren magani shine Glibomet. Zai dace lokacin da magani bai yi tasiri ba.

Koyaya, ya kamata a zubar da Glibomet idan akwai:

matsaloli tare da hanta,
na gazawar.

Sauran magungunan an zabi su ga mata masu juna biyu da masu shayarwa.

"Glibomet" wani lokacin yana haifar da sakamako masu illa a cikin hanyar:

rashin lafiyan cuta
tashin zuciya
tsananin farin ciki
fata fitsari da itching.

Ya kamata a sha maganin sosai kamar yadda kwararrun likitoci suka umarta.

Magungunan Ciwon Jiki

Idan mai haƙuri yana buƙatar magani don ciwon sukari na 2, zai iya karɓar magani na musamman. Akwai takamaiman jerin waɗanda ke lissafa duk magungunan zaɓe waɗanda aka wajabta wa marasa lafiya kowane wata idan akwai gaggawa.

Masu ciwon sukari na iya tsammanin su karɓi:

wasu kwayoyi - Acarbose, Glycvidon, Glibenclamide, Glucofage, Metformin, Gliclazide, Glimepiride, Rosiglitazone, Repaglinide,
insulin mafita don allura,
"Isofan-insulin" a cikin nau'i na dakatarwa,
100 g na ethyl giya,
insulin magunguna da allura.

Lokacin da mara lafiya ya buƙaci hormone, ana ba shi glucometer, har ma da abubuwan da ke da alaƙa, don gudanar da gwaje-gwaje uku a rana. Ana bayar da kuɗaɗe a ƙarancin farashi. Idan babu buƙatar insulin, to, yana yiwuwa a yi amfani da tsinkaye na gwaji na gwaji. Kuna iya amfani da tsiri daya a rana. Idan akwai matsaloli game da wahayi, ana samar da marasa lafiya kyauta tare da glucometers, kazalika da kayan da ke ba da izinin bincike guda ɗaya kowace rana.

Idan kun bi a hankali da tsananin bin shawarwarin likita, amfani da magunguna da aka tsara, ku bi abin da ake ci, ku kawar da samfuran cutarwa daga menu, yanayin zai haɓaka ta hanya mafi kyau kuma za a sarrafa nau'in ciwon sukari na 2. Kula da lafiya yana ba da tabbacin cikakken rayuwa ba tare da rikitarwa mai haɗari ba. Don yin wannan, kawai kuna buƙatar hana kwatsam a cikin sukari.