Allunan Emoxipin: umarnin don amfani

Emoxipine (INN - Emoxipine) wani angioprotector ne wanda ke rage matakin permeability na ganuwar jijiyoyin jiki saboda haɓaka hanyoyin tsattsauran ra'ayi, shima maganin yana da antioxidant da maganin rigakafi. Emoxipin zai rage danko na jini, daɗawar bango na jijiyoyin jiki, da kuma haɓakar basur. Bugu da ƙari, abubuwa masu aiki na ƙwayoyi zasu ƙara matakin abun ciki cyclic nucleotides a cikin kwakwalwa nama da jini platelet.

Fibrinolytic aiki na miyagun ƙwayoyi an bayyana shi a cikin gaskiyar cewa a yanayin saukan m lokacin bugun zuciya, dabarar tana da ikon fadada tasoshin jijiyoyin jini, ta haka ne ke iyakance fifikon mai hankali necrosis. Hakanan, haɓakar iyawar da kwanciyar hankali na zuciya zai inganta.

A matsayin abu na ophthalmic, Emoxipin yana da kayan karko, yana kare kwayar ido daga aikin hasken rana mai karfi. Saukad da Emoksipin zai taimaka don warware ciki na ciki da haɓaka aikin microcirculation a cikin ido.

Magunguna da magunguna

Pharmacodynamics

Kyakkyawan sakamako akan jini coagulation: ta rage rukunin coagulation gabaɗaya da rage ƙarancin farantin platelet, ƙwayar na tsawan lokacin coagulation jini. A membranes na sel da jini a karkashin aikin da miyagun ƙwayoyi sun daidaita, ƙwayoyin jini kara musu juriya hawan jini da mummunan rauni na injiniya.

Ingancin hanawa na iskar shaye shaye na lipids wanda yake a cikin bayanan halittun. Activityara ayyukan enzymes wanda ke da alhakin aikin antioxidant. Mai ikon samarwa sakamakon rage kiba ta rage kwayar cutar triglycerides.

Amincewa da Emoksipin zai iya rage bayyana maganin mahaifa. Yana da tasiri mai kyau a cikin kwanciyar hankali na cortex cortex zuwa ischemia da hypoxia. Gyara rashin cin gashin kansa a cikin yanayin hatsarin cerebrovascular.

Emoxipin yana da sakamako mai ma'ana na zuciya. Za'a kare tsarin na zuciya idan idan rauni ischemic rauni: Magungunan suna hana rarraba shi, da kuma fadada tasoshin jijiyoyin jini.

A matsayin ido ya sauke Emoxipin yana kare retina daga mummunan lalacewa sakamakon haɗuwa da hasken rana mai tsananin ƙarfi. Bugu da kari, saboda miyagun ƙwayoyi, keɓaɓɓe na basur a cikin ido mai yiwuwa ne.

Pharmacokinetics

Game da batun ƙwayar ciki na 10 mg a 1 kg na nauyin haƙuri, an lura da ƙarancin raguwa rabin kawar da miyagun ƙwayoyi. Constantarshen kawarwa shine 0.041 min, ƙararren rarraba shine 5.2 l, jimlar ɗaukar 214.8 ml a minti daya.

Magunguna yana sauri ya shiga gabobin da kyallen jikin mutum kuma shine ainihin abin da ya faru metabolism.

Kasuwancin magani na Emoxipin na iya bambanta dangane da yanayin mai haƙuri. Misali, a yanayin rashin lafiyar cuta mikakke occlusion, saurin da aka fitar da maganin zai rage, saboda ya zama yana da sauran kwayoyin halitta.

Game da maganin retrobulbar na Emoxipine, sinadaran da ke aiki da maganin sun bayyana kai tsaye a cikin jini, babban matakin kwanciyar hankali ya ci gaba na awa biyu, kuma bayan awanni 24 bayan gudanarwa, yanayin gudanarwar kusan kusan babu shi cikin jini. Wani ɓoye ƙwayoyi na miyagun ƙwayoyi an adana shi a cikin kyallen idanu.

Alamu don amfani da Emoxipin

A matsayin ido ya sauke alamu don amfani su ne:

ciki na ciki,
thrombosis a tsakiyar jijiya ta ido da reshenta,
glaucoma,
kariyar retina bayan coagulation laser da haske mai tsananin ƙarfi (dangane da kunar rana da zafin rana).

Alamu don amfani Emoxipin injections:

Hakanan, ana amfani da allurar Emoxipin idan yana da cuta da rashin lafiya rikicewar Sistem na kwakwalwaidan sanadin wadannan rikice-rikice basur ne da cutawar cuta. Idan ya cancanta, ana iya ba da maganin a matsayin allura ta wucin gadi, ko azaman allura ta cikin ampoules.

Side effects

Reactionsarancin halayen na iya faruwa taimakowanda bayan wani ɗan gajeren lokaci za a maye gurbinsa nutsuwa. Wataƙila karuwa cikin karfin jini da bayyanar kurji. Ana iya bayyanar da halayen yankuna ta hanyar jin zafi, ƙaiƙayi, ƙoshin abin wuta, jan launi da kuma matsanancin ƙwayoyin paraorbital.

Umarnin don amfani da Emoxipin (Hanyar da sashi)

Umarnin don Emoxipin - saukad da ido

Game da maganin retrobulbar na miyagun ƙwayoyi, ana gudanar da maganin kashi ɗaya cikin kashi ɗaya na 0.5 ml sau 1 kowace rana don kwanaki 10-15. Idan ana gudanar da maganin subconjunctival da parabulbar, to daga 0.2 zuwa 0.5 ml na miyagun ƙwayoyi ana gudanar da su sau ɗaya a rana don kwanaki 10-30.

Idan ya zama dole don kare ƙwayar maganin ƙwayar cuta, ana gudanar da maganin a cikin maganin maganin maganin kashewa a cikin 0.5 ml kowace rana da sa'a daya kafin coagulation na laser. A hanya ta dogara da mataki na ƙonewa da aka karɓa yayin coagulation na laser, a mafi yawan lokuta, ana amfani da saukad da retrobulbar sau ɗaya a rana daga kwana biyu zuwa goma.

Umarnin don Emoxipin - allura

A cikin zuciya da jijiyoyin jini, ana amfani da miyagun ƙwayoyi ne a cikin jijiya tare da digo a cikin ƙimar 20-40 na minti daya. Yawan maganin shine 20-30 ml na maganin kashi uku. Za'a iya ba da magudanan ruwa daga daya zuwa sau uku a rana don kwanaki 5-15. Tsawon lokacin jiyya ya dogara da nau'in cutar mai haƙuri. A ƙarshen masu sauke farali, suna canzawa zuwa injections na intramuscular na miyagun ƙwayoyi: 3-5 ml na maganin 3% ana allura sau 2-3 a rana. Hanyar yin allurar rigakafi daga ranakun 10 zuwa 30.

Ba a saki Emoxipin a ciki fom na kwamfutar hannu, saboda baza ku iya shan allunan Emoxipin ba, saboda kawai basa wanzu.

Yawan abin sama da ya kamata

Idan akwai yawan shaye-shaye na miyagun ƙwayoyi, bayyanar ko tsananin tasirin sakamako mai yiwuwa ne. Tare da yawan ƙwayar magani ko analogues, yana iya ƙaruwa hawan jinimatsanancin tashin hankali ko nutsuwa, jin zafi a zuciya, ciwon kai, tashin zuciyarashin jin daɗin ciki. Coagulation na jini na iya zama illa.

Yin magani na yawan zubar da Emoxipin da analogues na Emoxipin shine dakatar da miyagun ƙwayoyi kuma gudanar da hanyoyin maganin alamomin, idan ya cancanta.

Haɗa kai

Game da aikace-aikace tare da ac-tocopherol acetate, wataƙila tabbataccen aiki mai bayyanar da magungunan antioxidant na Emoxipin. Gabaɗaya, shan magani ba da shawarar haɗuwa tare da amfani da duk wasu magunguna ba tare da izinin likita ba.

Pharmacokinetics

Lokacin da aka gudanar da shi a cikin kashi 10 mg / kg, rabin cirewar Ti / g shine mintina 18, jimlar CI shine 0.2 l / min, kuma bayyananniyar ƙarar rarraba VD shine 5.2 l.

Magunguna yana sauri ya shiga cikin gabobin da kyallen takarda, inda aka ajiye shi da kuma metabolized. An samo metabolites biyar na emoxipin, waɗanda ke wakilta ta hanyar samfuran ma'amala da haɗuwa da canzawar ta, an samo su. Emoxipin metabolites da kodan ke cirewa. An samo mahimmancin 2-ethyl-6-methyl-3-hydroxypyridine-phosphate a cikin hanta.

A cikin yanayin cututtukan cuta, alal misali, a cikin batun ƙwayar jijiyoyin zuciya, canje-canje na magunguna na canje-canje na emoxipin. Yawan shakatawa yana raguwa, lokacin da emoxipin yake amfani da shi a cikin magudanar jini yana karuwa, wanda hakan na iya zama sakamakon dawowarsa daga depot, wanda ya hada da daga isyomic myocardium.

Ranar karewa

Shekaru 3 daga ranar fitowa.

Emoxipin magani ne na zamani. Onlyayansa kawai shine rauni mai ƙarfi na gida lokacin amfani dashi. Mutanen da ke fuskantar mummunan cututtuka na ophthalmic suna barin kyawawan abubuwan dubawa game da Emoxipine, saboda suna bin umarnin likita sosai kuma, saboda tsananin matsalar, a fili sun fahimci buƙatar magani. Idan ana amfani da miyagun ƙwayoyi don magance ƙananan cututtukan cututtukan cututtukan ƙwayar cuta, to, sake dubawa game da faɗuwar ba zai zama da tabbatacce ba: gaskiyar ita ce, ba kowa ne ya shirya don jure rashin jin daɗin ɗan lokaci ba bayan shan miyagun ƙwayoyi.

Likitocin dubawa game da ido ya sauke - musamman tabbatacce. Magungunan yana magance rashin aikin sa, kodayake yana haifar da rashin jin daɗi na ɗan lokaci a cikin marasa lafiya.

Emoxipin Injections da kyau rage tasirin cutar bugun jini da bugun zuciya a yawancin marasa lafiya a duniya. Hakanan, shan miyagun ƙwayoyi a cikin ɗan gajeren lokaci yana taimakawa rage bayyanar cututtuka daban-daban na rikicewar jijiyoyin jiki. Yana da ma'ana cewa an nuna irin wannan kwarewar amfani da amfani a cikin sake dubawa na kwarai, duka daga marasa lafiya da kuma daga likitoci.

Farashin Emoxipin, inda zaka siya

Kuna iya siyan Emoxipin a cikin Kiev ba tare da wata matsala ba: ana iya samun maganin ko analogues ɗin a kusan kowane kantin magani. Wannan kawai farashi zai iya bambanta dan kadan dangane da kantin magani, duk da haka, kusan dukkanin faduwar ido a cikin Ukraine, kuma sauran kwayoyi sun bambanta cikin farashi. Ya dogara ba kawai kan iyakar kantin kan magani ba, har ma a inda aka samar da shi, yawan fitarwa, da sauransu.

Matsakaicin farashin ido ya sauke emoxipin 1% a cikin kwalban kwalba na 5 ml yana gudana a kasuwa kusa da 60 UAH. Fakitin ampoules biyar 1 ml na kashi ɗaya Emoksipin No. 10 zai kashe kimanin 50 UAH a cikin kantin magani.