Jawai Takamatsu (Etamsylate)

Magungunan yana kunna ilimi thromboplastin damucopolysaccharidesda haka bayyana aikin hemostatic.

Normalizes jini coagulation kudi, ƙara zaman lafiyar da elasticity na ganuwar capillariesinganta matakai microcirculation har ma a cikin ƙananan tasoshin da capillaries.

Abin lura ne cewa maganin ba ya tasiri bayanan prothrombin kuma baya bada gudummawa ga ilimi jini clots. Idan ana gudanar da wakilin a cikin zuciya, to, tasirin yana faruwa ne a cikin mintina 10, bayan allura, kuma ya kai har zuwa awanni shida zuwa takwas.

Alamu don amfani

Menene kwayoyin hana daukar ciki?

An tsara allunan Ethamsilate:

• a zub da jini daban-daban asali
• a igiyar ciki na jini,
• tare da haila,
• yayin ayyukan tiyata,
• a likitan hakori, likitan dabbobi, akrology, tiyata da likitan mata,
• tare da raunin da kuma maganin farin jini,
• polymenorea,
• mai ciwon sukariciwon kai,
• basur na maganin basur.

Sau da yawa, ana sanya magani don lokuta masu nauyi, don rage zubar jini da hana faruwar hakan anemia.

Umarnin don amfani da Ethamsylate (Hanyar da sashi)

Sashi, hanyar gudanarwa da tsawon lokacin kulawa ya kamata likita ya ƙaddara.

Dangane da umarnin Ethamsylate a cikin allunan, ana gudanar da maganin a baki a 0.25-0.5 g (ɗaya ko biyu Allunan), ana rarraba shi zuwa allurai 3 ko 4. Ga yara, adadin yau da kullun shine 10-15 MG a kowace kilogiram na nauyi, ya kasu kashi uku.

Sodium Ethamyl a cikin mafita don allura ana amfani da shi ta hanyar injections (intramuscularly, cikin saukake) retrobulbar ko subconjunctival, gwargwadon shaidar.

Adadin yau da kullun shine giram 0.125-0.25 (don aikace-aikacen 3-4), matsakaicin adadin guda ɗaya shine 0.75 g (parenterally - har zuwa 0.375 g). Matsalar da za a yi amfani da ita. Ana amfani da swab a cikin shiri don rauni.

Hakanan ana amfani da kayan aiki a cikin aikin dabbobi. Sashi don kuliyoyi shine 0.1 ml a kilogiram na nauyin dabba, ana yin allurar yawanci sau biyu a rana.

Aikin magunguna

Ethamsylate wata hanya ce ta hanawa da dakatar da zub da jini. Yana shafar matakin farko na aikin hemostasis (hulɗa tsakanin endothelium da platelet). Ethamsylate yana ƙaruwa da adon farantin platelet, ya zama daidai da juriya na ganuwar farin jini, ta haka ne suke rage tasirinsu, kuma yana hana sinadarin prostsylandhesis, wanda ke haifar da rarrabuwa platelet, vasodilation da haɓaka izinin mulkin mallaka. Sakamakon wannan, lokacin zubar jini yana raguwa, an rage yawan zubar jini.

Pharmacokinetics

Bayan gudanarwa na jijiyoyin ƙwayar cuta, ana lura da sakamako mai zurfi bayan mintina 5 zuwa 15, ana samun mafi girman cikin awa 1. Magungunan suna da tasiri don sa'o'i 4-6, bayan haka sakamako ya ɓace a hankali. Bayan aiwatar da maganin etamsylate cikin kashi na MG 500, ana samun mafi girman matakin jini a cikin jini bayan mintuna 10 kuma shine 50 μg / ml.

Kusan 72% na maganin da aka gudanar ana share shi a cikin awanni 24 na farko tare da fitsari a cikin yanayin da bai canzawa ba. Ramin-etamsylate rabin jini daga plasma na jini shine kimanin awa 2. Ethamsylate ya haye shingen mahaifa kuma an keɓance shi cikin madara.

Contraindications

Hypersensitivity to etamsylate ko zuwa wani ɓangaren magungunan, tashin hankali zuwa sodium sulfite. Bronchial asma, m porphyria, ƙara yawan coagulation jini, basur wanda ya haddasa cututtukan anticoagulant, haemoblastosis (cutar lymphatic da cutar leukemia, osteosarcoma) a cikin yara.

Jiyya na iya farawa bayan ban da kasancewar mahaɗan fibrotic formations.

Formaddamar da tsari da abun da ke ciki

An ƙirƙira shi ta hanyar bayyananne, bayani mara launi don allura da biconvex, allunan farin allunan zagaye. An gano mafita a cikin gilashin ampoules na milimita 2 a cikin kwali na kwali. Allunan ana sayar da allunan a blisters da aka sanya a cikin kwali.

Sashi da gudanarwa

Kafin tiyata, ana sarrafa abubuwan ciki na 1-2 ampoules a cikin jijiyoyin ciki ko cikin intramuscularly. Yayin aikin, ana gudanar da abubuwan da ke cikin 1-2 ampoules cikin hanzari, ana iya maimaita aikin wannan kashi. Bayan tiyata, ana gudanar da abubuwanda ke cikin ampoules 1-2 a dukkan awanni 6 har sai hatsarin zubar jini ya shuɗe.

A cikin neonatology, Ethamsylate ana gudanar da shi ta intramuscularly ko cikin jijiya a kashi na 12.5 mg / kg nauyin jiki (0.1 ml = 12.5 mg). Dole ne a fara jiyya a cikin awanni 2 na farko bayan haihuwa. Ana gudanar da maganin a kowane sa'o'i b don kwanaki 4 zuwa jimlar 200 mg / kg.

Ana iya amfani da Ethamsylate a saman (fata ta hannu, hakar hakori) ta amfani da madaurin gauze mai taushi da miyagun ƙwayoyi.

Side sakamako

Daga tsarin mai juyayi: da wuya - ciwon kai, tsananin farin ciki, zubar ruwa, kasala, kasala na ƙananan ƙarshen.

Daga tsarin zuciya: da wuya - thromboembolism, jijiyoyin jini.

Daga narkewa kamar jijiyoyi: tashin zuciya, amai, jin zafi, gudawa.

Daga tsarin rigakafi: da wuya - halayen rashin lafiyan, zazzabi, fatar jiki, girgiza kai, an bayyana yanayin cutar angioedema. Daga tsarin numfashi: bronchospasm.

Daga tsarin endocrine: da wuya - m porphyria.

Daga tsarin musculoskeletal: da wuya - ciwon baya.

A wani ɓangaren fata: itching, urticaria.

Sauran: raguwa a cikin turaren nama, wanda aka maido dashi da kansa bayan wani lokaci.

Dukkanin sakamako masu illa suna da sauƙin kai da ƙwaya.

Yaran da aka kula dasu tare da etamsylate don hana zub da jini a cikin lymphatic m da myeloid cutar sankarar bargo na iya fuskantar cutar sikila.

Yin hulɗa tare da wasu kwayoyi

Idan Ethamsylate ya haɗu da ruwan gishiri, dole ne a shafa shi nan da nan.

Yarda da kai kafin gudanar da reopoliglycin yana hana tasirin rikicewar karshen abubuwa; gudanarwa bayan gudanar da reopoliglyukin bashi da tasiri ko cutarwa. Abinda aka yarda dashi tare da aminocaproic acid, vicasol.

Siffofin aikace-aikace

Yi amfani da hankali a cikin marasa lafiya waɗanda suka yi rikodin thrombosis ko thromboembolism, da kuma basur wanda mahaukacin anticoagulant ke haifar.

Tare da rikitarwa na basur wanda ke hade da yawan maganin cututtukan anticoagulants, ya wajaba don amfani da takamaiman maganin maye.

Magungunan ba su da tasiri tare da rage adadin platelet.

Kafin fara jinya, sauran abubuwan da ke haifar da zub da jini ya kamata a cire su.

Etamsylate lura da marasa lafiya da ke fama da matsalar jijiyoyin jini dole ne a haɗu tare da gabatarwar magungunan da ke kawar da ƙarancin inganci ko lahanin abubuwan da ke cikin tsarin coagulation na jini.

An hana shi amfani da miyagun ƙwayoyi idan ya canza launin launi na maganin allura.

Thearfin yin tasiri akan ƙimar amsawa lokacin tuki ko aiki tare da wasu hanyoyin.

Yayin jiyya tare da Etamsylat, yakamata a yi taka tsantsan yayin tuki motoci ko aiki tare da wasu hanyoyin, saboda tsananin wahala yana iya yiwuwa.

Clinical Pharmacology

Yana daidaita yanayin ƙa'idar aiki a cikin hanyoyin cututtukan cuta, inganta microcirculation, ƙara ƙarancin platelet, kuma yana da sakamako mai cutarwa. Tare da kunnawa / a cikin gabatarwar, tasirin hemostatic yana haɓaka bayan mintuna 5-15, mafi girman tasirin - bayan sa'o'i 1-2, tasirin yana ɗaukar sa'o'i 4-6 ko fiye. Tare da gabatarwar / m, sakamakon yana faruwa a hankali kaɗan.

Umarnin don amfani Ethamsylate (injections Allunan), sashi

Ana ɗaukar allunan a baki da ruwa.

Daidaitaccen sashi guda ɗaya na manya, bisa ga umarnin amfani da allunan Etamsylate, yana daga 250 zuwa 500 MG, matsakaicin shine 750 MG. Daidai gwargwadon yawanci likita ne yake tantance shi daban-daban.

Tare da metro da menorrhagia, ana wajabta 250 mg kowane 6 hours don 5-10 kwanaki, sannan 250 mg sau 2 a rana yayin zubar jini.

Tare da basur mai narkewa da kuma microangiopathies masu ciwon sukari, yawanci ana umurta 0.25-0.5 g 1-2 sau a rana.

Tare da hanji, huhun jini - 500 MG na kwanaki 5-10.

A cikin microbetiopathies masu ciwon sukari, allunan 1-2 a kowace rana ana wajabta su akan adadin watanni 2-3.

A cikin hanyar injections, Ethamsylate an yi nufin ne don intramuscular, ciki, retrobulbar, subconjunctival, sarrafa baka.

Manya: tare da ayyukan tiyata prophylactically - in / cikin / / awa 1 kafin aikin tiyata - 0.25-0.5 g ko a ciki, ba tare da la'akari da cin abinci ba, sa'o'i 3 kafin tiyata - 0.5-0.75 g. Idan ya cancanta - 0.25-0.5 g iv yayin aiki da prophylactally - 0.5-0.75 g iv, i / m ko 1.5-2 g a ciki, a ko'ina cikin rana - bayan aikin.

Yara: tare da ayyukan tiyata prophylactally - ta bakin, 1-12 mg / kg a cikin allurai kashi 2 don kwanaki 3-5. Idan ya cancanta, yayin aiki - in / a, 8-10 mg / kg.

Za'a iya amfani da allurar Ethamzilate a kai a kai (ana iya sanyawa daskararren kumburi da shafa wa rauni).

A cikin maganin ophthalmology, ana gudanar da maganin ta subconjunctival ko retrobulbar - a kashi na 0.125 g (1 ml 12.5% ​​bayani).

Side effects

Koyarwar tayi kashedin game da yuwuwar samun ci gaban sakamako masu zuwa yayin rubuta Ethamsylate:

• Girgiza kai a ciki
• Dizziness
• Burnwannafi
• Pressurearancin saukar karfin jini
• Hyperemia na fuska,
• Paresthesia daga cikin ƙananan ƙarshen,
• Ciwon kai.

Contraindications

An ba da izini don tsara etamsylate a cikin waɗannan lambobin:

• Hypersensitivity ga abubuwan da ke cikin miyagun ƙwayoyi,
• Thrombosis, thromboembolism, ƙara yawan jini,
• M nau'i na porphyria,
• Hemoblastosis (lymphatic da myeloid leukemia, osteosarcoma) a cikin yara.

• Tare da zub da jini a bango na yawan maganin cututtukan anticoagulants.

Bai kamata a yi amfani da Ethamsylate a matsayin magani kawai ba idan mai haƙuri yana da basur ta hanyar cututtukan anticoagulants.

Magunguna ba tare da sauran magunguna ba. Kada a haɗa a cikin sirinji iri ɗaya tare da sauran magunguna da abubuwa.

Yawan damuwa

Ba a bayar da bayanai ba.

Analogs Etamsilat, farashin a cikin kantin magunguna

Idan ya cancanta, ana iya maye gurbin Ethamsylate tare da analog don abu mai aiki - waɗannan magunguna ne:

1. Dicinon
2. Etamsilat Ferein,
3. Ethamsylate-KV,
4. Ethamsylate allura 12.5%.

Lokacin zabar analogues, yana da mahimmanci a fahimci cewa umarnin don amfani da Etamsilat, farashi da sake dubawa ba su shafi magungunan irin tasirin ba. Yana da mahimmanci don samun shawarar likita kuma kada kuyi canjin magani mai yanci.

Farashi a cikin kantin magunguna na Rasha: Etamzilat allurar 125mg / ml 2ml ampoules 10 - daga 108 zuwa 153 rubles, a halin yanzu babu bayanai akan farashin Allunan.

Store a cikin duhu wuri. Rayuwar shelf shine shekaru 3.

Sayarwa a cikin kantin magunguna ta takardar sayan magani.

3 sake dubawa don “Etamsilat”

Sun saka ni a asibiti bayan wani mummunan aiki, ya yi mummunar barna, likitocin sun ce na kusan zuwa duniyar gaba, amma Etamsilat ya fitar da ni. Zub da ciki na ciki bayan wannan maganin ya rufe kuma na tsira.

Ethamzilate an allura da zub da jini, yana da kyau fiye da tranexam, aƙalla ya taimaka mini sosai.

A wani lokaci, wannan magani ya taimake ni in dakatar da zubar jini da kuma kiyaye ciki!

Umarnin don amfani da Ethamsylate

Etamsilat mafi kyawun wakili (hemostatic) Etamsilat yana da alaƙar angioprotective, ayyukan yaduwa. Magungunan yana haifar da haɓaka ƙimar farawar platelet da ficewarsu daga riɓon ƙashi. Ana amfani da shi don dakatarwa da hana farin jini da zubar jini, zubar jini, a cikin tiyata, likitan mata, ophthalmic, hakori, urological da kuma otolaryngological aikatawa yayin ayyukan tiyata.

Sakamakon hemostatic na Etamsylate shine saboda samuwar thromboplastin a wurin da lalacewar jirgin ruwa da raguwar samuwar prostacyclin a cikin ganuwar jirgin ruwa, wanda ke haifar da dakatarwa ko raguwa a zub da jini. Ayyukan antihyaluronidase na babban bangaren yana hana halakar mucopolysaccharides na ganuwar capillaries, yana ƙaruwa da juriya da rage ƙwayar cuta. Shan magungunan ba shi da tasirin vasoconstrictor, baya bayar da gudummawa ga thrombosis.

Abun ciki da nau'i na saki

Ana amfani da Etamsylate na miyagun ƙwayoyi a cikin nau'ikan sashi biyu - allunan don maganin baka da kuma mafita don allura na ciki ko allura. Allunan farin convex suna dauke da 250 MG na babban sinadaran aiki (sodium ethamylate) da sauran abubuwan taimako (sodium hydrogen phosphate dihydrate, sodium metabisulfite, povidone, sitaci dankalin turawa, stearate alli). Kunsasshen a cikin blisters don 50 ko 100.

Umarnin don amfani Ethamsylate (hanya da sashi)

An tsara shi don baka, subconjunctival, intravenous, intramuscular da retrobulbar amfani.

• A / ciki, cikin / m na 1 h kafin tiyata, don rigakafin - 0.25-0.5 g (2-4 ml na 12.5% ​​bayani). Idan akwai haɗarin zubar jini bayan jini - 0.5-0.75 g (4-6 ml) kowace rana.
• Idan ya cancanta, ana sarrafa 0.25-0.5 (2-4 ml) a cikin kwarzana. Don dalilai na magani - 0.25-0.5 g (2-4 ml) a lokaci, sannan kuma - 0.25 g a kowane sa'o'i 4-6. Kuna iya shiga / nutsuwa, yana karawa hanyoyin mafita na al'ada don jiko.
• Tare da metro da menorrhagia, ana wajabta 0.25 g kowane 6 hours don 5-10 kwanaki, to 0.25 g sau 2 a rana a lokacin basur.
• Tare da basur mai narkewa da kuma microangiopathies masu ciwon sukari, yawanci ana umurta 0.25-0.5 g 1-2 sau a rana.
• Sashi don subconjunctival da retrobulbar amfani da milliliter ne.

Sashi da gudanarwa

Tsawon lokacin jiyya tare da amfani da Etamsilat, makirci da tsari na gudanarwa, ƙarar abu ɗaya kuma na yau da kullun ana ƙaddara ta hanyar halartar likita dangane da ganewar asali da alamu. Sashi shawarar da umarnin don amfani shine:

• lokacin da aka sha shi a baki: 250-500 MG 3-4 sau a rana (guda, guda guda don gudanar da maganin magana yana ƙaruwa zuwa 750 MG tare da alamun da suka dace),
• intramuscularly ko cikin kwali: 125-250 mg, 3-4 injections kowace rana,
• don tsarin gudanarwa na parenteral: har zuwa 375 MG,
• a cikin ƙuruciya: 10-15 mg / kg kowace rana, injections guda 3 a rana, daidai gwargwado.

Allunan Ethamsylate

An wajabta gudanar da maganin na baka don magancewa da rigakafin zub da jini a cikin microangiopathies da diathesis. Ethamzilate na lokaci mai nauyi kuma don magance cututtukan sake zagayowar ana kuma bada shawarar don maganin baka. Zai yiwu jiyya na likita:

• Mita da ɓarna yayin haila da lura da ƙwayar mahaifa wanda ke zubar da ciki - 0.5 g sau ɗaya a kowane 6 na awa, lokacin jiyya - kwanaki 5-12. Ta rigakafi - 1 kwamfutar hannu sau 4 a rana akan ranakun jinni, kuma don kwana biyu na sake zagayowar.
• Ciwon mara na zuciya - 1-2 Allunan sau 2-3 a rana, tsawon lokacin kulawa 2-3 watanni.
• Yin rigakafin haɗarin zubar jini bayan jini - allunan 6-8 a rana tare da rarraba allurai a kowane kashi na awa 24.

Etamsylate a cikin ampoules

Ana amfani da allurar ta Ethamsilate don hana zub da jini kafin da bayan tiyata tare da alamun da suka dace (2-4 ml intramuscularly ko cikin jijiya, awa daya kafin tiyata). Idan akwai haɗarin zub da jini bayan jini, ana yin allurar 4-6 a kowace rana. Tsarin aikace-aikacen da za a iya amfani da su:

• diathesis na jini - 1.5 g, allura daya a rana, tsawon lokaci 5-14 days,
• a cikin maganin ophthalmology - 0.125 g (1 ml na mafita) subconjunctival ko retrobulbar,
• a cikin aikin dabbobi - 0.1 ml a kilo kilogram na nauyin dabba sau 2 a rana.

Etamzilate yayin daukar ciki

Yayin cikin ciki, an wajabta etamsylate tare da taka tsantsan. Ba'a ba da shawarar don amfani dashi a lokacin farkon farkon ba. Tare da bayyanar tabo ko kuma barazanar ɓarna a wani lokaci na gaba, ana amfani dashi a hade tare da Progesterone tare da sanya ido a kan maganin coagulation koyaushe. Yakamata alƙawarin ya zama likita wanda ya jagoranci daukar ciki, shan magani zai iya haifar da mummunan sakamako ga lafiyar mahaifiyar ko tayin.

Hulɗa da ƙwayoyi

Ba a yarda da haɗakar maganin Ethamsylate a cikin sirinji iri ɗaya tare da sauran magunguna ba. Tare da kwatankwacin jiyya tare da rukunin magunguna na dextrans, tare da gabatarwar wani magani tare da sashi na 10 MG / kg sa'a daya kafin gudanarwar su, raguwar aikin antiplatelet mai yiwuwa ne, gwamnatin bayan ba ta da tasirin hemostatic. An halatta ayi amfani dashi da aminocaproic acid, sodium menadione bisulfite.

Side effects da yawan abin sama da ya kamata

Hanyar magani tare da yin amfani da Ethamsilate a mafi yawan lokuta ana yarda da shi sosai, ƙarƙashin tsarin kulawa, sashi na yau da kullun. Babu batun rahoton yawan zubar da yaɗuwa da aka bayar da rahoto, tare da zubar jini mai rikitarwa wanda ya haifar da yawan ƙwayoyin maganin maye, ana nuna takamaiman maganin rashin amfani. Matsaloli masu yuwuwar amfani da shan magani:

• jin rashin jin daɗi ko konewa a yankin kirji,
• ƙwannafi
• ciwon ciki
• anemia
• a rage matsin lamba,
• hyperemia na fata na fuskar,
• ciwon kai da farin ciki,
• hauhawar jini
• saukar da saukar karfin jini,
• paresthesia na fata (numbness, tingling sensation) na ƙananan ƙarshen.

Sharuɗɗan sayarwa da ajiya

Ana bayar da maganin Ethamsylate a cikin magunguna kamar yadda likita ya umarta. Kiyaye samfurin zuwa ga yara, a wuri mai duhu, a zazzabi da bai wuce 25 ° C ba. Rayuwar shelf - shekaru biyu daga ranar da aka nuna akan kunshin.

Kadai cikakkiyar rajista cikakke tsarin tsarin magani na Ethamsilate shine Dicinon. Idan an samu sakamako masu illa ko kuma aka sami haƙuri guda ɗaya, likitan halartan ɗin zai yi sau ɗaya tare da ɗayan magungunan masu zuwa:

Farashin Etamzilat

Kuna iya siyan Etamsylat a cikin kantin magani ko kan albarkatun Intanet na musamman, shirya bayarwar gida. Matsakaicin farashin kowane nau'i na sakin:

Matsakaicin farashin, a cikin rubles

Magani don gudanarwar ciki da jijiyoyin jini, ampoules A'a 10 10 ml 12.5%

Oksana, dan shekara 28. Ethamsilate a likitan mata na wata-wata ya ba ni shawarar in ci bayan haihuwa ta biyu saboda karuwar zubar jini da take hakkokin lokacin zagayowar. Na sha a cikin allunan bisa ga ka'idar da aka tsara - allunan 4 a cikin kowane 6 hours a cikin kwanakin 8 na farko na sake zagayowar. Duk abin da aka tsara tuni a watan na biyu na shigowa, hanya ta tafi ƙarshe. Babu wani sakamako masu illa.

Anna, shekara 42. Tare da zubar cikin mahaifa bayan zubar da cikin ta, an sanya hanyar allurar Ethamsilate - allura biyu a rana sau 7. Zub da jini ya tsaya bayan allura biyu na farko. Samfurin ba shi da tsada, yana aiki da sauri, babu wasu sakamako masu illa, yanayin lafiyar gaba ɗaya yayin hanya bai canza ba. Farashi mai jijiyar ciki, ya jure hanyar da kyau.

Marina, tana da shekara 33. A lokacin daukar ciki, an adana ta a makwanni 18 saboda tsananin tabo. Ethamzilate an allurar dashi cikin kwana biyu (ampoule sau biyu a rana), sannan kuma yacika 5 kwanaki intramuscularly daya ampoule kowace rana. An lura da hutawa a gado, zubar jinni ya tsaya bayan kwanaki 3. Bugu da ari, ciki ya ci gaba ba tare da faruwa ba, yaron yana cikin koshin lafiya.

Farashi a cikin kantin magani

Farashin Etamzilat don kunshin 1 ya fito ne daga 108 rubles.

Bayyanar akan wannan shafin fasalin mai sauƙin fasalin hukuma na bayanin maganin. An bayar da bayanin ne don dalilai na ba da bayani kawai kuma ba jagora ba ne don maganin kansa. Kafin amfani da miyagun ƙwayoyi, dole ne ka nemi ƙwararren masani kuma ka san kanka tare da umarnin da masana'anta suka gindaya.