Mikardis® (40 mg) Telmisartan

Magungunan suna da farin allunan farin launi mai launi tare da zane 51H a gefe guda kuma alamar kamfanin a wannan gefen.

7 irin waɗannan allunan tare da sashi na 40 MG a cikin kumburi; 2 ko 4 irin wannan blister a cikin kwali. Ko dai irin waɗannan allunan 7 da allurai na 80 MG a cikin kuzari, 2, 4 ko 8 irin waɗannan blister a cikin kwali

Magunguna da magunguna

Pharmacodynamics

Telmisartan - mai zaɓar mai karɓar mai karɓa karafarirani II. Yana da babban tashin hankali zuwa AT1 mai karɓar mai karɓa karafarirani II. Gasa tare da karafarirani II a takamaiman masu karɓa ba tare da samun sakamako iri ɗaya ba. Abin ɗaurewa yana ci gaba.

Ba ya bayyanar da tsattsauran ra'ayi saboda sauran nau'ikan masu karɓar karɓa. Yana rage abun ciki aldosterone a cikin jini, baya kashe plasma renin da ion tashoshi a sel.

Fara sakamako mai ban tsoro An lura da shi a cikin awanni uku na farko bayan gudanarwa telmisartan. Aikin ya ci gaba har kwana daya ko fiye. Tasirin da aka ambata yana tasowa bayan wata guda bayan gudanarwa na yau da kullun.

A cikin mutane da hauhawar jinitelmisartan yana rage zafin jini na systolic da diastolic, amma ba ya canza yawan yawan cututtukan zuciya.

Ba ya haifar da ciwon cirewa.

Pharmacokinetics

Lokacin da aka sha shi a baki, yana narkewa da sauri daga hanji. Bioavailability yana gab da 50%. Bayan awanni uku, yawan ƙwayar cutar ta zama mafi girman. Kashi 99.5% na abubuwa masu aiki suna ɗaure su ga garkuwar jini. Metabolized ta hanyar amsa tare da acid na glucuronic. Metabolites na miyagun ƙwayoyi ba su da aiki. Rage rabin rayuwa ya fi awanni 20. An cire ta ta hanyar narkewar hanji, fitar cikin fitsari ya kasa da 2%.

Contraindications

Allunan Micardis suna contraindicated a cikin mutane tare da rashin lafiyan mutum a kan abubuwan da ke cikin miyagun ƙwayoyi, masu nauyi cututtukahanta kokoda,rashin jituwa, yayin daukar ciki da lactation, yara yan kasa da shekaru 18.

Side effects

• Daga tsarin juyayi na tsakiya: bacin raitsananin farin ciki ciwon kaigajiya, damuwa, rashin bacci, katsewa.
• Daga tsarin numfashi: cututtukan cututtukan tsokoki na sama (sinusitis, pharyngitis, mashako), tari.
• Daga tsarin kewaya: fadi saukar da matsin lamba, samarin, bradycardiaciwon kirji.
• Daga tsarin narkewa: tashin zuciya, zawo, dyspepsiakara maida hankali ne hanta enzymes hanta.
• Daga tsarin musculoskeletal: myalgialow ciwon baya arthralgia.
• Daga tsarin halittar jini: edema, cututtukan cututtukan kwayoyin halittar jini, hypercreatininemia.
• Amincewar Lafiya Jiki: Fata na fata, angioedema, cututtukan mahaifa.
• Manunin dakin gwaje-gwaje: anemia, hyperkalemia.
• Sauran: erythemaitching dyspnea.

Mikardis, umarnin don amfani

Dangane da umarnin don amfani da Mikardis, ana ɗaukar magani a baka. Nagari ne ga manya kashi 40 MG sau daya a rana. A cikin yawan masu haƙuri, ana lura da tasirin warkewa lokacin da kashi20 MG kowace rana. Idan ba a lura da rage matsin lamba zuwa matakin da ake so ba, to ana iya ƙara kashi zuwa 80 MG kowace rana.

Ana samun tasirin sakamako mai guba a makonni biyar bayan farawar jiyya.

A cikin marasa lafiya tare da siffofin mai tsanani hauhawar jini mai yiwuwa amfani 160 MGmagani kowace rana.

Haɗa kai

Telmisartan kunna sakamako mai ban tsoro wasu hanyoyin rage karfin matsin lamba.

Lokacin amfani dashi telmisartan da digoxin na lokaci tabbacin maida hankali ne dole digoxin a cikin jini, kamar yadda zai iya tashi.

Lokacin shan magunguna tare lithium da ACE masu hanawa za a iya lura da ƙara karuwa na ɗan lokaci lithiuma cikin jini, wanda aka bayyana ta hanyar sakamako masu guba.

Jiyya magungunan anti-mai hana kumburi tare da Mikardis a cikin marassa lafiya marasa lafiya na iya haifar da ci gaban rashin lafiyar koda.

Umarni na musamman

Domin masu fama da rashin ruwa (ƙuntatawa gishiri, magani kamuwa da cuta, zawo, vomiting) raguwa a cikin adadin Mikardis wajibi ne.

Tare da taka tsantsan, sanya mutane da stenosisna biyu na koda, mitral bawul stenosisko maganin cututtukan jini na aortic toshewa, matsanancin kumburin ciki, hepatic ko gajiyawar zuciya, cututtuka na narkewa.

An hana yin amfani da lokacin da firamaren farkoda rashin jituwa.

Tare da yin niyyar ciki, da farko dole ne a sami wanda zai maye gurbin Mikardis tare da wata maganin rigakafi.

Yi amfani da hankali lokacin tuki.

Tare da amfani da concomitant tare da kwayoyi lithium Kulawa da abubuwan da ke cikin lithium a cikin jini an nuna shi, tunda haɓaka ɗan lokaci na matakinsa yana yiwuwa.

Form sashi

Allunan 40 MG, 80 MG

Tabletaya daga cikin kwamfutar hannu ya ƙunshi

abu mai aiki - telmisartan 40 ko 80 MG, bi da bi,

magabata: sodium hydroxide, povidone K 25, meglumine, sorbitol P6, magnesium stearate.

Allunan 40 MG - allunan da ke kama da juna, fararen fata ko kusan fararen fata, tare da alamar 51N a gefe ɗaya da tambarin kamfanin a ɗayan, tare da biconvex farfajiya, kauri daga 3.6 - 4.2 mm.

Allunan kwayoyi 80 - kwamfutar hannu mai kama da launi, fari ko kusan fararen fata, tare da alamar 52N a gefe ɗaya da tambarin kamfanin a ɗayan, tare da biconvex farfajiya, 4.4 - 5.0 mm lokacin farin ciki.

Kayan magunguna

Pharmacokinetics

Ana ɗaukar Telmisartan cikin sauri, adadin da aka sha yana bambanta. Matsayin na telmisartan shine kusan 50%.

Lokacin ɗaukar telmisartan lokaci guda tare da abinci, raguwa a cikin AUC (yanki a ƙarƙashin tsarin lokaci-lokaci) ya tashi daga 6% (a kashi 40 mg) zuwa 19% (a kashi na 160 mg). 3 hours bayan shigowa, maida hankali ne a cikin matakan jini na jini ya fita, ba tare da cin abincin ba. Decreasearamin raguwa a cikin AUC ba ya haifar da raguwa a cikin tasirin warkewa.

Akwai bambanci a cikin yawan ƙwayar plasma a cikin maza da mata. Cmax (mafi girman maida hankali) da AUC sun kasance kusan sau 3 da 2 a cikin mata idan aka kwatanta da maza ba tare da tasiri mai mahimmanci ba.

Sadarwa tare da ƙwayoyin plasma fiye da kashi 99.5%, akasarinsu tare da albumin da glycoprotein alpha-1. Ofimar rarraba kusan lita 500.

Telmisartan yana metabolized ta hanyar haɗa kayan farawa tare da glucuronide. Babu wani aikin magunguna na conjugate da aka samo.

Telmisartan yana da yanayin yanayin inshora na likitancin tare da ƙarshen cire rabin rayuwa> 20 sa'o'i. Cmax da - zuwa ƙarancin ƙa'ida - AUC yana ƙaruwa da yawan rarraba tare da kashi. Babu wani muhimmin taro na telmisartan da aka gano.

Bayan gudanar da maganin baka, telmisartan kusan an cire shi ta cikin hanjin bai canza ba. Jimlar urinary excretion kasa da 2% na kashi. Jimlar aikin zubar jini yana da yawa (kusan 900 ml / min) idan aka kwatanta da hawan jini na hepatic (kamar 1500 ml / min).

Tsofaffi marasa lafiya

Magungunan likitancin telmisartan a cikin tsofaffi marasa lafiya ba su canzawa.

Marasa lafiya tare da gazawar koda

A cikin marasa lafiya tare da gazawar renal suna fuskantar hemodialysis, ana lura da ƙananan ƙwayar plasma. A cikin marasa lafiya da gazawar renal, telmisartan yana da alaƙa da sunadaran plasma kuma ba a keɓe shi ba lokacin dialysis. Tare da gazawar koda, rabin rayuwa baya canzawa.

Marasa lafiya tare da raunin hanta

A cikin marasa lafiya da rashin isasshen hepatic, cikakken bioavailability na telmisartan yana ƙaruwa zuwa 100%. Rabin rayuwar don gazawar hanta baya canzawa.

Magungunan likita na allura biyu na telmisartan an kimanta su a cikin marasa lafiya da cutar hawan jini (n = 57) masu shekaru 6 zuwa 18 bayan shan telmisartan a allurai 1 mg / kg ko 2 mg / kg na tsawon makonni huɗu na magani. Sakamakon binciken ya tabbatar da cewa magungunan likitanci na telmisartan a cikin yara 'yan ƙasa da shekaru 12 sun yi daidai da waɗanda ke cikin manya kuma, musamman, an tabbatar da yanayin Cmax.

Pharmacodynamics

MIKARDIS ingantacce ne kuma takamaiman (mai zaɓa) angiotensin II mai karɓar antagonist (nau'in AT1) don gudanarwa na baka. Telmisartan tare da ƙaƙƙarfan alaƙa yana kawar da angiotensin II daga rukunin yanar gizon da ke ɗaure shi a cikin karɓa mai karɓa na AT1, wanda ke da alhakin sanannen tasirin angiotensin II. Telmisartan bashi da tasirin agonist akan mai karɓar AT1. Telmisartan da aka zaɓi za a ɗaura wa masu karɓar AT1. Haɗin yana ci gaba. Telmisartan bai nuna kusanci ga sauran masu karɓar ba, gami da karɓar AT2 da sauran su, ƙarancin masu karɓar AT karɓar.

Babban mahimmancin mahimmancin waɗannan masu karɓar, da kuma tasirin tasirin tasirinsu mai yawa tare da angiotensin II, wanda yake ƙaruwa wanda yake ƙaruwa tare da alƙawarin telmisartan, ba a yi nazari ba.

Telmisartan yana rage matakan plasma aldosterone, baya toshe renin a cikin tashoshin plasma na mutum da ion.

Telmisartan ba ya hana enzyme angiotensin-mai canzauri (kinase II), wanda ke lalata bradykinin. Don haka, babu ƙara girman tasirin sakamako masu dangantaka da aikin bradykinin.

A cikin mutane, kashi 80 MG na telmisartan kusan gaba ɗaya yana hana karuwar hawan jini (BP) wanda ya haifar da angiotensin II. Ana kiyaye tasirin hana abubuwa cikin sa'o'i 24 kuma har yanzu an ƙaddara shi bayan awanni 48.

Jiyya da mahimmancin jijiya

Bayan shan kashi na farko na telmisartan, hawan jini yana raguwa bayan sa'o'i 3. Ana samun mafi ƙarancin hauhawar jini a cikin mako 4 bayan fara magani kuma ana kiyaye shi na dogon lokaci.

Tasirin antihypertensive yana ɗaukar sa'o'i 24 bayan shan maganin, ciki har da awowi 4 kafin ɗaukar kashi na gaba, wanda aka tabbatar da shi ta hanyar ƙididdigar ƙwaƙwalwar ƙwayar ƙwayar cuta, da daidaituwa (sama da 80%) na mafi ƙima da matsakaiciyar ƙwayar bayan shan 40 da 80 MG na MIKARDIS a gwajin asibiti da aka sarrafa. .

A cikin marasa lafiya tare da hauhawar jini, MIKARDIS yana rage duka systolic da diastolic matsa lamba ba tare da canza canjin zuciya ba.

Tasirin antihypertensive na telmisartan idan aka kwatanta shi da wakilan sauran azuzuwan magungunan antihypertensive, kamar: amlodipine, atenolol, enalapril, hydrochlorothiazide, losartan, lisinopril, ramipril da valsartan.

Game da batun sokewar MIKARDIS na wucin gadi, sannu a hankali hawan jini ya dawo cikin dabi'un kafin magani na tsawon kwanaki ba tare da alamun saurin tashin jini ba (babu "koma-baya" ciwo).

Nazarin asibiti ya nuna cewa telmisartan yana da alaƙa da ƙimar ƙididdigar yawan jama'a a hagu ventricular taro da hagu ventricular taro index a cikin marasa lafiya da jijiyoyin jini da jijiyoyin jini na hagu.

Marasa lafiya tare da hauhawar jini da nephropathy mai ciwon sukari da aka bi da MIKARDIS suna nuna raguwar ƙididdigar ƙididdigar ƙwayar proteinuria (gami da microalbuminuria da macroalbuminuria).

A cikin gwaje-gwaje na asibiti na ƙasa da yawa, an nuna cewa akwai ƙarancin yawan maganganun bushewa a cikin marasa lafiya waɗanda ke shan telmisartan fiye da marasa lafiya da ke karɓar inhibitors na enzyme (ACE inhibitors).

Yin rigakafin cututtukan zuciya da mace-mace

A cikin marasa lafiya 55 shekara da haihuwa tare da tarihin cututtukan zuciya na zuciya, bugun jini, cututtukan jijiyoyin jiki ko cutar sankarau tare da lalacewar ƙwayar cuta (retinopathy, hauhawar jini ventricular, macro da microalbuminuria), yin amfani da MIKARDIS na iya rage faruwar cutar myocardial infarction, bugun jini, da kuma asibiti don cunkoso rashin karfin zuciya da rage mace-mace daga cututtukan zuciya.

An kiyasta tasirin antimispertensive na telmisartan a cikin marasa lafiya tare da hauhawar jini wanda ke da shekaru 6 zuwa 18 (n = 76) bayan shan telmisartan a kashi na 1 mg / kg (bi da n = 30) ko 2 mg / kg (bi da n = 31) na tsawon makonni huɗu na magani .

Matsin jini na Systolic (SBP) a matsakaici ya ragu daga ƙimar farko ta 8.5 mm Hg da 3.6 mm Hg. a cikin rukunan telmisartan, 2 mg / kg da 1 mg / kg, bi da bi. Tsarin jini na Diastolic (DBP) a matsakaici ya ragu daga ƙimar farko ta 4.5 mmHg. da 4.8 mmHg a cikin rukunan telmisartan, 1 mg / kg da 2 mg / kg, bi da bi.

Canje-canje ya kasance mai dogaro ne da kashi.

Bayanan kare lafiya yana daidai da wannan a cikin marasa lafiyar manya.

Sashi da gudanarwa

Jiyya da mahimmancin jijiya

Yawan shawarar da aka bayar da shawarar manya shine 40 MG sau ɗaya kowace rana.

A cikin halayen da ba a cimma karfin cutar da ake so ba, ana iya karɓar kashi na MIKARDIS zuwa matsakaicin 80 MG sau ɗaya a rana.

Lokacin da aka kara yawan ƙwayar, ya kamata a la'akari da cewa mafi girman tasirin antihypertensive ana samun mafi yawa a cikin makonni huɗu zuwa takwas bayan farawar magani.

Za a iya amfani da Telmisartan a hade tare da thiazide diuretics, alal misali, hydrochlorothiazide, wanda a hade tare da telmisartan yana da ƙarin tasirin hypotensive.

A cikin marasa lafiya tare da matsanancin hauhawar jini, kashi na telmisartan shine 160 MG / day (capsules biyu na MIKARDIS 80 MG) kuma a haɗe tare da hydrochlorothiazide 12.5-25 mg / day an sami haƙuri da kyau kuma yana da tasiri.

Yin rigakafin cututtukan zuciya da mace-mace

Yawan shawarar da aka bada shawarar shine 80 MG sau ɗaya kowace rana.

Ba a tantance ko allurai da ke ƙasa da MG 80 na da tasiri wajen rage ƙwayar zuciya da mutuwa ba.

A matakin farko na amfani da telmisartan don rigakafin cututtukan zuciya da mace-mace, ana ba da shawarar cewa za a sa ido a kan karfin jini (BP), kuma ana iya daidaita matakan hawan jini tare da kwayoyi masu rage karfin hawan jini.

Ana iya ɗaukar MIKARDIS ba tare da la'akari da cin abinci ba.

Ba a buƙatar canje-canje na marasa lafiya a cikin marasa lafiya tare da gazawar renal, ciki har da marasa lafiya akan hemodialysis. Ba a cire Telmisartan daga jini a lokacin zubar jinni ba.

A cikin marasa lafiya da ke fama da rauni na matsakaici zuwa matsakaici, kashi na yau da kullun kada ya wuce 40 MG sau ɗaya a rana.

Ba a buƙatar gyaran gyaɗa.

Babu aminci da tasirin amfani da MIKARDIS a cikin yara 'yan ƙasa da shekaru 18.

Abun ciki da aikin magani na Mikardis

Babban kayan aiki na maganin shine Telmisartan. A cikin kwamfutar hannu ɗaya zai iya ƙunsar 80, 40 ko 20 MG. Wadanda suka kware a cikin magungunan da ke inganta shan manyan abubuwan sune meglumine, sodium hydroxide, polyvidone, sorbitol, steneste magnesium.

Mikardis mai maganin antagonist ne na angiotensin-2. Wannan hormone yana kara sautin jijiyoyin jijiyoyin bugun jini, wanda ke haifar da raguwa a cikin katuwar tasoshin. Telmisartan a cikin tsarin kemikal dinsa yayi daidai da masu karɓar angiotensin AT1 masu karɓa.

Bayan shiga jiki, Mikardis ya kulla yarjejeniya tare da masu karɓar AT1 kuma wannan yana haifar da fitowar angiotensin, wato, an kawar da dalilin karuwar hawan jini. Telmisartan yana haifar da raguwa a cikin matsin lamba na systolic da diastolic, amma wannan sinadari baya canza ƙarfi da adadin yawan rikicewar ƙwayar zuciya.

Amfani da farko na Mikardis yana haifar da daidaituwa a hankali na hauhawar jini - a hankali yana raguwa sama da awanni uku.Ana lura da tasirin antihypertensive bayan shan allunan a kalla a rana guda, wato, don ci gaba da matsin lamba, kana buƙatar shan maganin sau ɗaya kawai a rana.

Matsakaicin matsakaici da tsauraran matsin lamba yana faruwa bayan makonni huɗu zuwa biyar daga farkon jiyya tare da Mikardis. A cikin abin da ya kasance an soke maganin nan take, sakamakon cirewa baya haɓaka, shine, karfin jini baya komawa zuwa ga alamu na asali da kyau, yawanci wannan yana faruwa ne a cikin 'yan makonni.

Dukkanin abubuwan da ke cikin Mikardis, lokacin da aka kawo ta baki daga hanjinsu, ana shan su da sauri, yanayin ilimin maganin ya kai kusan kashi 50%. Matsakaicin yawan abu mai aiki a cikin plasma an ƙaddara shi bayan 3 hours.

Metabolization yana faruwa ta hanyar amsa telmisartan tare da glucuronic acid, sakamakon metabolites ba su da aiki. Cire rabin rayuwar sa yayi sama da awanni 20. Magungunan da aka sarrafa ana keɓe su tare da feces, ƙasa da 2% na maganin an saki tare da fitsari.

Lokacin amfani

An tsara magungunan Mikardis don magance hauhawar jini. Wasu likitoci suna ba da magani ga marasa lafiya fiye da shekara 55 waɗanda ke da ha ari don haɓaka cututtukan cututtukan zuciya masu alaƙa da hawan jini.

Baya ga Mikardis na yau da kullun, akwai kuma Mikardis Plus. Wannan magani, ban da telmisartan, ya ƙunshi ƙarin 12.5 MG na hydrochlorothiazide, wannan abu shine diuretic.

Haɗin mai diuretic da antagonist antagonist yana ba ka damar cimma sakamako mai girma na miyagun ƙwayoyi. Ana amfani da maganin diuretic kamar awa biyu bayan shan kwayoyin. Koyarwa don mycardis da ƙari yana nuna cewa an tsara wannan maganin idan ba zai yiwu ba a cimma ragowar matsa lamba da ake buƙata yayin ɗaukar hanyar da ta saba da ƙwayar maganin rashin ƙarfi.

Lokacin da Mikardis yake contraindicated

Mikardis 40 yana da daidai iri ɗaya kamar Allunan kamar kwayoyi tare da adadin adadin abubuwa masu aiki. Jiyya tare da wannan magungunan antihypertensive ba a za'ayi:

• Idan hypersensitivity ga babban ko ƙarin abubuwan da ke cikin miyagun ƙwayoyi an kafa,
• Dukkanin watanni uku na ciki da lokacin shayarwa,
• Idan mai haƙuri yana da maganin cutar biliary fili wanda ke shafar iyawar su,
• Tare da manyan take hakki a cikin aikin hanta da kodan,
• Tare da rashin haƙuri na fructose rashin haƙuri.

Mikardis analogues dole ne a nemi shi don magance hauhawar jini a cikin samari da yara, wannan saboda gaskiyar cewa tasirin telmisartan akan kwayoyin da basu da tsari.

Koyarwar don mycardis da ƙari yana nuna cewa, ban da contraindications na sama, bai kamata a tsara magunguna ga marasa lafiya da raunin hypercalcemia na hyperkalemia ba, tare da rashi lactase da rashin haƙuri ga lactose da galactose.

Akwai contraindications na kwatankwacin maganin mycardis. Wato, likita yakamata ya yi taka-tsantsan kuma ya fara magani tare da rage ragi, idan tarihin hauhawar jini shine:

• Hyponatremia ko hyperkalemia,
• CHD - ischemia na zuciya,
• Cututtukan zuciya - gazawar koda, mara nauyi, ƙwayar cuta,
• Stenosis na tsokoki guda biyu na kodan - idan mai haƙuri yana da koda guda ɗaya, yakamata a yi taka tsantsan lokacin da ake rubuta magungunan ƙwayar cuta idan akwai ƙwaƙwalwar ƙwayar jijiyar jini kawai,
• Guban ruwa na haifar da amai da gudawa,
• Na baya magani tare da diuretics,
• Sake murmurewa bayan kamuwa da koda.

M sakamako masu illa

Reviews Mycardis ba koyaushe ne tabbatacce ba. Wasu marasa lafiya suna lura da bayyanar canje-canje masu ban sha'awa iri-iri a cikin kwanciyar hankali, kuma haɓaka su kai tsaye ya dogara da yawan ƙwayoyi, a kan shekarun mai haƙuri da kuma gaban haɗuwa da cututtukan cuta. Mafi sau da yawa, waɗannan canje-canje masu yiwuwa ne:

• Nau'in lokaci, ciwon kai, gajiya da damuwa, bacin rai, rashin bacci, a lokuta mafi ƙaranci, raɗaɗi.
• Ara mai saurin kamuwa da tsarin na numfashi ga cututtukan da ke kama mutum, wanda hakan ke haifar da pharyngitis, sinusitis, mashako da tari na huhu.
• Rashin kamuwa da cuta ta hanji, amai da gudawa, da gudawa. A cikin wasu marasa lafiya, gwaje-gwaje sun nuna karuwar enzymes hanta.
• Hypotension, kirji, tachycardia, ko kuma mataimakin bradycardia.
• Ciwon kirji, arthralgia, jin zafi a cikin kashin lumbar.
• Rashin lalacewa ga ƙwayar ƙwayar cuta, riƙewar ruwa a cikin jiki.
• Allergic halayen a cikin nau'i na fata rashes, urticaria, angioedema, itching, erythema.
• A cikin gwaje-gwaje na dakin gwaje-gwaje - hyperkalemia da alamun anemia.

Karatuttukan karatu na farko na Mikardis sun kafa tasirin maganin ƙwayar cuta. A wannan batun, ba a son yin amfani da wannan magani a duk lokacin daukar ciki.

Idan an shirya juna biyu, to mara lafiyar, a kan shawarar likita, ya kamata ya canza zuwa magungunan antihypertensive mafi aminci. A cikin halin da ake ciki na ciki a kan asalin magani tare da Mikardis, an dakatar da gudanar da wannan magani nan da nan.

Siffofin aikace-aikace

Dole ne likitan Mikardis ya zama likita ya tsara shi kuma ana iya amfani dashi duka daban-daban kuma tare da wasu magunguna waɗanda aikin su shine inganta aikin tsarin jijiyoyin jini. Maƙerin ya ba da shawarar ci abinci na yau da kullun don iyakance ga kwamfutar hannu guda Mikardis tare da 40 MG na kayan aiki mai aiki.. Amma dole ne a ɗauka a cikin zuciya cewa a cikin marasa lafiya tare da hawan jini, m sakamako mai hypotensive wani lokacin yakan ci gaba lokacin shan magani tare da kashi na 20 MG.

Zaɓin sashin warkewa yana gudana ne aƙalla makonni 4. Yana ɗaukar lokaci mai yawa don maganin don nuna cikakkiyar tasirin warkewarta. Idan ba a cimma sakamakon da ake so ba a wannan lokacin, to, ana bada shawarar mai haƙuri ya ɗauki Mikardis 80, kwamfutar hannu ɗaya kowace rana. A cikin nau'ikan nau'in hauhawar jini, ana iya tsara 160 mg na telmisartan, wato, zai ɗauki allunan biyu na 80 MG kowane.

A cikin wasu halaye, ba zai yuwu a cimma raguwar faɗuwar hauhawar jini ba yayin amfani da magani guda. Likita ya ba da shawarar irin waɗannan marasa lafiya su sayi Mikardis ƙari,, godiya ga diuretic ɗin da aka haɗa a cikin wannan samfurin, matsin lamba yana raguwa da sauri kuma mafi kyau. Ana zabar kashi na hada magunguna dangane da tsananin cutar hauhawar jini. Binciken mycardis da ƙarin tabbacin sakamako mai tasirin gaske.

Ana shan magani a kowane lokaci na rana, cin abinci baya shafar ƙwaƙwalwar abubuwan da ke cikin miyagun ƙwayoyi. Matsakaicin janar na likita an ƙaddara shi, gwargwadon lafiyar mai haƙuri, likita na iya ba da shawarar sauya zuwa kashi na goyon baya na 20 MG.

Yadda Mikardis yayi hulɗa tare da wasu kwayoyi

Idan ya zama dole don amfani da kwayoyi tare da telmisartan, likita ya kamata gano irin magungunan da mai haƙuri har yanzu yake sha. Tare da gudanar da sabis na lokaci-lokaci na adadin kwayoyi, tasirin su ko tasirin Mikardis na iya ƙaruwa.

• Telmisartan yana haɓaka kayan aikin rigakafi na sauran magunguna tare da irin wannan sakamako,
• Tare da lura na lokaci daya tare da Digoxin da Mikardis, maida hankali kan abubuwan da ke tattare da magunguna na farko yana ƙaruwa
• Hankalin Ramipril yana ƙaruwa kusan sau 2,5, amma ba a ƙaddara mahimmancin asibiti game da tasirin maganin biyu ba,
• Yawan yawan kayayyakin da ke dauke da kayan lithium yana haɓaka, wanda ke tattare da haɓaka sakamako masu guba a jiki,
• Tare da kulawar NSAIDs da telmisartan a cikin lokaci guda a cikin marasa lafiya da rashin ruwa a jiki, haɗarin haɓaka haɓaka na yara da raguwa a cikin mummunan sakamako na Mikardis yana ƙaruwa.

Sakamakon abu mai aiki akan iyawar sarrafa abubuwa masu rikitarwa

Umarnin da aka haɗa don amfani da Mikardis 80 MG da 40 MG na nuna cewa ba a gudanar da gwaje-gwaje na musamman ba game da yadda shan maganin ke shafan hankalin mutum da saurin halayensa. Koyaya, lokacin shan magunguna tare da tsarin aikin hypotensive na aiki, koyaushe ku tuna cewa magunguna na wannan rukuni galibi suna haifar da nutsuwa da rashin damuwa lokaci-lokaci. Idan ma'aikatan da ke da alaƙa da aiki tare da keɓaɓɓun hanyoyin suna da alamu iri ɗaya, to ya kamata a ba su analogues na mycardis.

Siffofin ajiya

Dole ne a adana miyagun ƙwayoyi inda ba a cire damar da yake da ita ga yara ba. Zazzabi a wurin ajiya kada ya zama ya fi digiri 30. Allunan suna da allurai na 40 da 80 MG ana adana su ba tare da keta mutuncin blister ba sama da shekaru 4 daga ranar da aka kirkira su. Allunan 20 MG na da gajeriyar rayuwar shiryayye na shekaru 3.

Farashin Mikardis ya dogara da sashi na abu mai aiki a cikin magani. Kuna iya siyan Mikardis 40 tare da allunan guda 14 a kowace fakitin 500 da ƙarin rubles. Kuna iya siyan Mikardis 80 tare da allunan 28 a cikin kantin magani a matsakaita na 950 rubles. Farashin mycardis da na allunan 28 yana farawa daga 850 rubles.

Gabaɗaya, sake dubawa game da miyagun ƙwayoyi Mikardis suna da gaskiya - mutanen da suke amfani da bayanin miyagun ƙwayoyi wani haɓakar ci gaba ne na sakamako masu illa da rage hauhawar hawan jini. Amma da yawa daga cikin sayen wannan magani an dakatar da babban farashinsa.

Dole ne likita ya zaɓi analogues mai rahusa na mycardis, shahararrun kwayoyi tare da irin wannan sakamako sun haɗa da: