Umarnin Diabinax (Diabinax) don amfani

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

PRING microcrystalline cellulose, sitaci, povidone, sodium methylparaben, colloidal silicon dioxide (Aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakakken ruwa.

10 inji mai kwakwalwa - blister (1) - fakitoci na kwali.
Guda 20. - blister (1) - fakitoci na kwali.

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

PRING microcrystalline cellulose, sitaci, povidone, sodium methylparaben, colloidal silicon dioxide (Aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakakken ruwa.

10 inji mai kwakwalwa - blister (1) - fakitoci na kwali.
Guda 20. - blister (1) - fakitoci na kwali.

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

PRING microcrystalline cellulose, sitaci, povidone, sodium methylparaben, colloidal silicon dioxide (Aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakakken ruwa.

10 inji mai kwakwalwa - blister (1) - fakitoci na kwali.
Guda 20. - blister (1) - fakitoci na kwali.
10 inji mai kwakwalwa - blister (6) - fakitoci na kwali.

Aikin magunguna

Diabinax magani ne mai yawan jini wanda aka samo shi daga ƙarni na sulfonylurea II. Yana karfafa rufin insulin ta hanyar farji, yana sanya tasirin insulin-sirrin glucose, kuma yana kara karfin jijiyoyin kwayoyin zuwa insulin. Yana ƙarfafa aikin enzymes na ciki - tsoka glycogen synthetase. Yana rage lokacin daga lokacin cin abinci zuwa farkon insulin insulin. Yana dawo da farkon farkon ɓoyewar insulin (sabanin sauran abubuwan da ake buƙata na sulfonylurea, alal misali, glibenclamide da chlorpropamide, waɗanda ke shafar yawancin lokacin mataki na biyu na ɓoye). Yana rage hauhawar jini bayan abinci.

Baya ga shafar metabolism, yana shafar microcirculation. Yana rage hauhawar jini bayan abinci. Yana rage adhesin platelet da tarawa, yana rage jinkirin ci gaban thrombus na bango. Yana daidaita yanayin motsawar jijiyoyin jiki, yana hana haɓakar microthrombosis, yana maido da tsarin ƙoshin lafiyar parietal fibrinolysis.

Yana rage jijiyoyin bugun zuciya zuwa adrenaline. Ya na da anti-atherogenic Properties, saukar da taro na jimlar cholesterol a cikin jini.

Yana sane da haɓakar ciwon sikila a wani matakin da ba yaɗa yawa ba. Tare da nephropathy na ciwon sukari tare da amfani na tsawan lokaci, akwai raguwa mai yawa a cikin proteinuria.

Ba ya haifar da karuwa a cikin nauyin jiki, saboda yana da tasiri mai mahimmanci a farkon farkon ƙwayar insulin kuma ba ya haifar da hyperinsulinemia, yana taimakawa rage nauyin jiki a cikin marasa lafiya masu kiba, bin tsarin da ya dace.

Pharmacokinetics

Lokacin da aka sha shi a baki, ƙwayar tana da amfani sosai daga narkewa. C max a cikin plasma na jini an kai shi tsawon awanni 4 bayan shan magani guda na 80 MG. Shafaffen furotin na Plasma kashi 94%. An metabolized a cikin hanta tare da samuwar metabolites da yawa. Kodan ya keɓe shi - 70% a cikin hanyar metabolites, ƙasa da 1% an keɓe shi baya canzawa a cikin fitsari, tare da feces - 12% a cikin hanyar metabolites. T 1/2 - kimanin awa 12

Dos na miyagun ƙwayoyi DIABINAX

An saita kashi na miyagun ƙwayoyi daban-daban, gwargwadon shekarun mai haƙuri, alamun bayyanar cututtuka na cutar da matakin azumin glycemia da sa'o'i 2 bayan cin abinci. Aikin yau da kullun shine 80 MG, matsakaici na yau da kullun shine 160 mg, kuma mafi girman kullun shine 320 mg. Ana shan Diabinax a baki sau 2 / rana (safe da maraice) mintuna 30-60 kafin abinci.

Hulɗa da ƙwayoyi

Sulfanilamides, salicylates, maganin rashin daidaituwa, magungunan anabolic, beta-blockers, fibrates, chloramphenicol, phenfluramine, fluoxetine, guanethidine, MAO inhibitors, pentoxifylline, theophylline, maganin kafeyin, phenylbutazone, tlinecycline na tlinecycline kuma tlinecycline tlinecycline kuma tlinecycline tlinecycline kuma tlinecycline tlinecycline kuma tlinecycline tlinecycline kuma tlinecycline tlinecycline kuma tlinecycline tlinecycline kuma tlinecycline tlinecycline

Tare da yin amfani da gliclazide da acarbose a lokaci guda, ana lura da ƙarin tasirin hypoglycemic, wanda ke buƙatar daidaita sashi na waɗannan kwayoyi.

Cimetidine yana kara yawan gliclazide a cikin jini na plasma, wanda zai iya haifar da mummunan hypoglycemia (rashin damuwa na tsakiya, rashin hankali), saboda haka, ba a bada shawarar yin amfani da waɗannan magunguna ba.

Barbiturates, chlorpromazine, glucocorticosteroids, sympathomimetics, glucagon, nicotinic acid, estrogens, progestins, maganin hana haihuwa, diuretics, rifampicin, cututtukan thyroid, sinadarin lithium yana raunana tasirin hypoglycemic na glyclazide.

Yin amfani da abubuwan gliclazide da na abubuwanda aka kirkira (hade da miconazole) lokaci daya.

Fitar saki, marufi da abun da ke ciki Diabinax

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

Fitowa: celclosese microcrystalline, sitaci, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakakken ruwa.

Guda 20. - blister (2) - fakitoci na kwali.
Guda 20. - blister (3) - fakitoci na kwali.

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

Fitowa: celclosese microcrystalline, sitaci, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakakken ruwa.

Guda 20. - blister (2) - fakitoci na kwali.
Guda 20. - blister (3) - fakitoci na kwali.

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

Fitowa: celclosese microcrystalline, sitaci, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakakken ruwa.

Guda 20. - blister (2) - fakitoci na kwali.
Guda 20. - blister (3) - fakitoci na kwali.

DIABINAX - sakamako masu illa

Daga tsarin endocrine: hypoglycemia (tare da yawan wuce gona da iri da / ko rashin isasshen abinci).

Allergic halayen: fatar fata, urticaria, pruritus.

Daga tsarin narkewa: da wuya - anorexia, tashin zuciya, amai, gudawa, jin wani nauyi ko jin zafi a yankin na jijiyoyin wuya.

Daga tsarin hemopoietic: thrombocytopenia, leukopenia ko agranulocytosis, anemia (yawanci ana juyawa).

Umarnin na musamman game da shan DIABINAX

Ana aiwatar da aikin Diabinax a hade tare da ƙarancin kalori, ƙarancin carb.

A lokacin jiyya, yakamata ku kula da matakin azumin glycemia da kuma bayan cin abinci.

Tare da taka tsantsan, ya kamata a yi amfani da miyagun ƙwayoyi a cikin marasa lafiya da ke fama da ƙarancin adrenal, cututtuka na glandar thyroid (tare da aiki mai rauni), pyelonephritis na kullum, da barasa.

Game da mummunan raunin da ya faru, cututtuka masu kamuwa da cuta, ayyukan tiyata, yuwuwar yin amfani da shirye-shiryen insulin ya kamata a la'akari.

Daidaitawar magani ya zama dole don wuce gona da iri da motsin rai, canji a abinci.

Game da yin Azumi ko shan giya, hadarin kamuwa da jini ya karu.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

Yayin jiyya, ba da shawarar shiga cikin ayyukan da ke buƙatar natsuwa da saurin amsawa.

Contraindications

Hypersensitivity, nau'in 1 mellitus na ciwon sukari, ketoacidosis na masu ciwon sukari, precoma na ciwon sukari da coma, hepatic mai tsanani da / ko gazawar koda, ciki, cikin lactation, a karkashin shekaru 18. Gargadi. Yanayin asibiti wanda sau da yawa yana buƙatar gudanar da insulin (manyan ayyukan tiyata da raunin da ya faru, ƙonewa mai yawa, cututtukan cututtuka tare da cututtukan febrile), shan giya, tsufa.

Yadda ake amfani: sashi da hanya na jiyya

A ciki, yayin abinci, kashi na farko na yau da kullun shine 80 MG, matsakaici na yau da kullun shine 160-320 mg (don 2 allurai, da safe da maraice). Yawan yana dogara ne da shekaru, tsananin girman cutar siga, maida hankali ga yawan glucose na jini da kuma awanni 2 bayan cin abinci.

Ana ɗaukar allunan saki na 30 MG sau ɗaya kullun tare da karin kumallo. Idan aka rasa magungunan, to rana mai zuwa bai kamata a kara yawan maganin ba. Yankin da aka bada shawarar farko shine 30 MG (gami da mutane sama da 65). Kowane sashi na canzawa na iya aiwatarwa bayan akalla tsawon sati biyu. Yawancin yau da kullun kada ya wuce 120 MG. Idan mara lafiya ya taɓa karɓar magani tare da sulfonylureas tare da T1 / 2 mafi tsayi (alal misali, chlorpropamide), saka idanu a hankali (1-2 makonni) ya zama dole don guje wa hypoglycemia saboda ƙaddamar da tasirin su.

Tsarin magunguna don tsofaffi marassa lafiya ko a cikin marasa lafiya da rauni ga matsakaiciyar matsakaici na gazawar ƙwaƙwalwar ƙwayar cuta (CC 15-80 ml / min) daidai yake da wanda ke sama.

A hade tare da insulin, ana bada shawarar 60-180 MG a duk rana.

Nau'i na Diabinax, sakin magunguna da abun da ke ciki.

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

Shafin 1
gliclazide
20 MG
-«-
40 MG
-«-
80 MG

Fitattun abubuwa: microcrystalline cellulose, sitaci, povidone, sodium methyl paraben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakken ruwa.

Guda 20. - blister (2) - fakitoci na kwali.
Guda 20. - blister (3) - fakitoci na kwali.

LITTAFIN SAURARON SAUKI.
Duk bayanan da aka bayar an gabatar dasu ne kawai don fahimtar tare da miyagun ƙwayoyi, ya kamata ka nemi likita game da yiwuwar amfani.

Rashin sakamako Diabinax:

Daga tsarin narkewa: da wuya - anorexia, tashin zuciya, amai, gudawa, zazzabin cizon sauro.

Daga tsarin hawan jini: a wasu yanayi - thrombocytopenia, agranulocytosis ko leukopenia, anaemia (yawanci ana juyawa).

Daga tsarin endocrine: tare da yawan zubar jini - hypoglycemia.

Allergic halayen: fatar fata, itching.

Umarnin na musamman don amfanin Diabinax.

Ana amfani da Gliclazide don magance mellitus na rashin insulin-insulin a hade tare da ƙarancin kalori, ƙananan carb.

A lokacin jiyya, ya kamata ku kula da matakin glucose a cikin jini akai-akai a kan komai a ciki kuma bayan cin abinci, yawan canzawar yau da kullun a cikin matakan glucose.

Dangane da ayyukan tiyata ko zubar da cututtukan ƙwayar cutar sankara, ana buƙatar la'akari da yiwuwar amfani da shirye-shiryen insulin.

Tare da haɓakar hypoglycemia, idan mai haƙuri yana da hankali, an tsara glucose (ko kuma maganin sukari) a ciki. Idan aka rasa asara, ana gudanar da aikin glucose din cikin jiki, a cikin intramuscularly ko a cikin jijiyar wuya. Bayan murmurewa, ya zama dole a ba mai haƙuri abincin da ke da wadataccen abinci a cikin carbohydrates don guje wa sake farfadowa da ƙwanƙwasa jini.

Tare da yin amfani da gliclazide na lokaci guda tare da verapamil, ana buƙatar saka idanu na yau da kullun game da matakan glucose na jini, tare da acarbose, kulawa da hankali da kuma gyaran hanyoyin kwantar da hankali na wakilai na hypoglycemic.

Yin amfani da gliclazide da cimetidine a lokaci guda ba a bada shawarar ba.

Haɗin Diabinax tare da wasu kwayoyi.

Tasirin hypoglycemic na gliclazide yana da ƙarfi a cikin amfani tare da takaddun pyrazolone, salicylates, phenylbutazone, antibacterial sulfonamides, theophylline, maganin kafeyin, MAO inhibitors.

Yin amfani da lokaci-lokaci na amfani da abubuwanda ke hana beta-blockers yana haifar da yiwuwar haɓaka hypoglycemia, kuma yana iya rufe tachycardia da rawar jiki, halayyar hypoglycemia, yayin da zufa na iya ƙaruwa.

Ta yin amfani da gliclazide da acarbose, a lokaci guda, ana lura da ƙarin tasirin hypoglycemic.

Cimetidine yana kara yawan gliclazide a cikin plasma, wanda zai haifar da matsanancin rashin ƙarfi (rashin damuwa na CNS, ƙarancin sani).

Tare da yin amfani da lokaci ɗaya tare da GCS (gami da siffofin sashi don amfani na waje), diuretics, barbiturates, estrogens, progesins, magungunan estrogen-progestogen hade, diphenin, rifampicin, tasirin hypoglycemic na glyclazide ya ragu.

Side effects

Hypoglycemia (take hakkin tsarin allurar rigakafi da rashin isasshen abinci): ciwon kai, gajiya, yunwar, karin gumi, rauni mai yawa, bugun zuciya, bacci, rashin bacci, tashin hankali, tashin hankali, damuwa, damuwa, damuwa, damuwa, damuwa, damuwa, rashin damuwa, gazawar maida hankali da jinkirta rashin jin daɗi, bacin rai, rauni, gani, rashin damuwa, rashi, numfashi, raunin hankali, sanyin numfashi, sanyin jiki dicardia.

Daga tsarin narkewa: dyspepsia (tashin zuciya, zawo, jin wani nauyi a cikin epigastrium), rage ci - ƙarancin jiki yana raguwa tare da abinci, da wuya - raguwar hanta (cholestatic jaundice, ƙara yawan aiki na "hanta" transaminases).

Daga gabobin hemopoietic: hanawa ƙwaƙwalwar ƙwayar jini (anemia, thrombocytopenia, leukopenia).

Allergic halayen: itching, urticaria, maculopapular fatar.

Sauran: hangula na fata da hucin mucous overdose. Bayyanar cututtuka: hypoglycemia, ƙwaƙwalwar ƙwaƙwalwa mai narkewa, ƙwaƙwalwar ƙwayar cuta.

Jiyya: idan mai haƙuri yana da hankali, ɗauki sukari a ciki, tare da rikicewar hankali - a / cikin gabatarwar maganin hypertonic dextrose (40%), 1-2 mg na glucagon / m, kula da maida hankali na glucose jini a kowane minti na 15, da kuma ƙaddarar pH urea, creatinine, da jini electrolytes. Bayan murmurewa, ya zama dole a ba mai haƙuri abincin da ke da wadataccen ƙwayoyin carbohydrates cikin sauki (don guje wa sake haɓakar cutar sanƙara). Tare da cututtukan maɓallin cerebral edema, mannitol da dexamethasone.

Tsarin saki, abun da aka shirya da marufi

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

Fitattun abubuwa: microcrystalline cellulose, sitaci, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakken ruwa.

Guda 20. - blisters (2) - fakitoci na kwali. - blister (3) - fakitoci na kwali.

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

Fitattun abubuwa: microcrystalline cellulose, sitaci, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakakken ruwa.

Guda 20. - blisters (2) - fakitoci na kwali. - blister (3) - fakitoci na kwali.

Allunan fararen fata ne, zagaye, lebur, tare da gefunan da aka yanke da lahani a gefe guda.

Fitattun abubuwa: microcrystalline cellulose, sitaci, povidone, sodium methylparaben, colloidal silicon dioxide (aerosil), magnesium stearate, sodium sitaci glycolate, talc, tsarkakakken ruwa.

Guda 20. - blisters (2) - fakitoci na kwali. - blister (3) - fakitoci na kwali.

Abun ciki da nau'i na saki

1 kwamfutar hannu 1 ya ƙunshi glycoslide 20, 40 ko 80 MG, kazalika da excipients (MCC, sitaci, povidone, sodium methyl paraben, colloidal silicon dioxide / aerosil, magnesium stearate, sodium sitaci glycolate, talc, tsarkakakken ruwa), a cikin gilashin kunshin 10 inji mai kwakwalwa. ., a cikin kwali 6 na fakiti.

Sashi da gudanarwa

A ciki, mintuna 30-60 kafin abinci sau 2 a rana (safe da maraice).An zaɓi kashi ɗaya daban-daban, gwargwadon shekarun mai haƙuri, alamun bayyanar cututtuka na cutar da kuma matakin azumin glycemia da sa'o'i 2 bayan cin abinci. Yawancin lokaci, farawa na yau da kullun shine 80 MG, matsakaici shine 160 mg / day, kuma mafi girman shine 320 mg / day.

Diabinax shiryayye magungunan rayuwa

Kada kayi amfani bayan ranar karewa wanda aka nuna akan kunshin.

Ka bar bayananka

Neman Bayanan Bincike na Yanzu, ‰

Rijistar Mahimmancin magunguna da mahimmanci

Takaddun shaida na Diabinax

• P N014190 / 01

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DIABINAX: DOSAGE

An saita kashi na miyagun ƙwayoyi daban-daban, gwargwadon shekarun mai haƙuri, alamun bayyanar cututtuka na cutar da matakin azumin glycemia da sa'o'i 2 bayan cin abinci. Aikin yau da kullun shine 80 MG, matsakaici na yau da kullun shine 160 mg, kuma mafi girman kullun shine 320 mg. Ana shan Diabinax a baki sau 2 / rana (safe da maraice) mintuna 30-60 kafin abinci.

Yawan abin sama da ya kamata

Bayyanar cututtuka: pallor na fata, tachycardia, yunwar, karuwar gumi, rawar jiki, a cikin manyan lokuta - mai raunin hankali.

Jiyya: idan mai haƙuri yana da hankali, ana yin maganin glucose ko kuma maganin sukari ta bakin. Game da asarar hankali, ana gudanar da maganin glucose na 40% ko glucagon s / c, i / m, i / v ana gudanar da iv. Bayan murmurewa, ya zama dole a ba mai haƙuri abincin da ke da wadataccen abinci a cikin carbohydrates don guje wa sake farfadowa da ƙwanƙwasa jini.

DIABINAX: TARIHIN KYAUTA

Daga tsarin endocrine: hypoglycemia (tare da yawan wuce gona da iri da / ko rashin isasshen abinci).

Allergic halayen: fatar fata, urticaria, pruritus.

Daga tsarin narkewa: da wuya - anorexia, tashin zuciya, amai, gudawa, jin wani nauyi ko jin zafi a yankin na jijiyoyin wuya.

Daga tsarin hemopoietic: thrombocytopenia, leukopenia ko agranulocytosis, anemia (yawanci ana juyawa).