Actovegin® (5 ml) hemoderivative maraƙi mara nauyi
Marasa lafiya tare da cututtukan da ke a tsakiya da tsarin juyayi na tsakiya ana bi da su tare da maganin antioxidants, jami'in antiplatelet da magungunan vasoactive. Likitoci na iya yin amfani da allunan Actovegin don hypoxia, kumburi, da raunin da ke haifar da rashin isashshen sunadarin oxygen a cikin sel. Sanar da kanka tare da nau'in sakin, abun da ke ciki, alamomi don amfani, tsarin aikin da analogues na miyagun ƙwayoyi.
Actovegin - abin da ke taimakawa
Actovegin yana da tasirin da ke tattare da ƙwayoyin jijiya. Ana amfani da miyagun ƙwayoyi sau da yawa a cikin lura da cututtukan da ke hade da tsarin juyayi. Magungunan suna da waɗannan abubuwan:
- yana ƙara yawan motsa jiki,
- yana inganta haɓakar oxygen ta kyallen takarda,
- stimulates metabolism (cell metabolism),
- yana inganta yin amfani da iskar oxygen, jigilar glucose a cikin kyallen jiki.
Kowane mutum yana da iyaka game da aikin yau da kullun na metabolism na makamashi (ba a samar da kyallen takarda tare da iskar oxygen ba, ƙwanƙwasa oxygen yana raguwa, hypoxia yana faruwa), kuma akasin haka, suna ƙara yawan amfani da makamashi (farfadowa na nama). Magungunan yana taimakawa haɓaka abubuwa ta jiki, yana da tasirin gaske akan tsarin samar da jini. Magani yana da tasiri musamman ga cututtukan da ke gudana.
Form sashi
Allurar 40 MG / ml - 2 ml, 5 ml
abu mai aiki - karancin jinin haila (dangane da batun bushewa) * 40.0 MG.
magabata: ruwa don yin allura
* ya ƙunshi kimanin 26.8 mg na sodium chloride
M, bayani rawaya.
Magunguna da magunguna
Actovegin tsohuwar rigakafi ce. An samo shi ta amfani da dialysis da ultrafiltration. Magungunan yana da tasiri mai kyau a cikin jigilar kai da amfani da glucose, yana daidaita ƙwayoyin plasma na sel yayin ischemia ta amfani da iskar oxygen. Kayan aiki ya fara aiki rabin sa'a bayan shigowa. Ana iya lura da tasirin sakamako bayan sa'o'i 3.
Ba a yi nazarin Pharmacokinetics sosai ba, amma duk abubuwan da ke tattare da magunguna suna nan a jikin mutum a yanayin halittarsa. Ba a samu raguwar tasirin magungunan ƙwayoyi ba a cikin mutanen da ke fama da cutar hepatic ko gazawar, canji na metabolism wanda ke hade da tsufa. Ba a yi nazari kan sabbin jarirai ba, musamman yin la’akari da halayen metabolism, sabili da haka an ba da shawarar yin amfani da shi da taka tsantsan kuma kawai kamar yadda likitan halartar ya gabatar ne.
Actovegin - alamomi don amfani
Sakamakon jiko na miyagun ƙwayoyi, haɗuwa da haemoglobin, DNA da hydroxyproline yana ƙaruwa. Dangane da bayanin umarnin, ana amfani da waɗannan allunan azaman magani na taimako don:
- ischemic da basur,
- raunin kwakwalwa da rauni da kuma encephalopathy,
- rikicewar jijiyoyin jini,
- illa gaɗaɗɗɗan jijiyoyi.
A cikin ciwon sukari na mellitus, magani yana rage ciwo ko ƙonewa a cikin ƙananan ƙarshen, ana amfani dashi don ƙonewa, ban da digiri na 4, don warkar da raunuka da sauran raunuka fata. Bugu da ƙari, kayan aiki yana taimakawa haɓakawa:
- metabolism
- venous jini jini zuwa kwakwalwa,
- kewaye jini kewaye.
Kayan magunguna
Pharmacokinetics
Ba shi yiwuwa a yi nazarin halayen pharmacokinetic (ɗaukar, rarrabawa, ragi) na Actovegin®, tunda ya ƙunshi abubuwan kawai na kayan aikin yau da kullun a cikin jikin mutum.
Actovegin® yana da tasirin rigakafin ƙwayar cuta, wanda ke fara bayyana a cikin minutesan mintuna 30 bayan gudanarwar aikin parenteral kuma ya kai matsakaici akan matsakaici bayan sa'o'i 3 (2-6 hours).
Pharmacodynamics
Actovegin® antihypoxant. Actovegin® shine hemoderivative, wanda aka samo shi ta hanyar dialysis da ultrafiltration (mahadi tare da nauyin kwayar ƙasa da ƙasa 5000 daltons pass). Actovegin® yana haifar da organancin kai mai zaman kansa na energyarfafa metabolism a cikin sel. An tabbatar da aikin Actovegin® ta hanyar auna karuwar shanshi da kuma ƙara yawan amfani da glucose da oxygen. Wadannan tasirin guda biyu suna da alaƙa, kuma suna haifar da karuwa a cikin ayyukan samar da ATP, ta hanyar samar da babban adadin kuzari zuwa sel. A karkashin yanayin da ke iyakance ayyukan yau da kullun na metabolism na makamashi (hypoxia, rashin substrate), kuma tare da karuwar amfani da makamashi (warkarwa, sake haɓakawa) Actovegin® yana ƙarfafa ayyukan haɓaka aiki na metabolism na aiki da kuma anabolism. Sakamakon sakandare yana ƙaruwa cikin jini.
Tasirin Actovegin® a kan ɗauka da amfani da iskar oxygen, kazalika da aikin insulin-kamar motsa jiki tare da haɓakar jigilar glucose da ƙona abu, suna da yawa a cikin aikin kulawa da ciwon sukari na polyneuropathy (DPN).
A cikin marasa lafiya da masu ciwon sukari mellitus da masu ciwon sukari na polyneuropathy na Actovegin reduces suna rage alamun polyneuropathy (raɗaɗin raɗaɗi, ƙonawa mai ƙarfi, parasthesia, numbness a cikin ƙananan ƙarshen). Babu shakka, ana rage rikicewar hankali, kuma inganta lafiyar kwakwalwa na marasa lafiya yana inganta.
Sashi da gudanarwa
Actovegin®, allura, ana amfani dashi intramuscularly, intravenously (ciki har da nau'in infusions) ko intraarterially.
Umarnin don amfani da ampoules tare da hutu ɗaya:
theauki ampoule domin saman da ke ɗauke da alamar ya kasance a saman. Taya a hankali tare da yatsa da kuma girgiza ampoule, bada izinin mafita daga magudanar ampoule. Kashe saman ampoule ta latsa alamar.
a) Yawancin shawarar shawarar:
Ya danganta da tsananin zafin hoto, kashi na farko shine 10-20 ml a ciki ko a cikin ciki, sannan 5 ml iv ko a hankali IM kullun ko sau da yawa a mako.
Lokacin amfani dashi azaman infusions, 10-50 ml an narke a cikin 200-300 ml na isotonic sodium chloride bayani ko 5% dextrose bayani (mafita tushe), gwargwadon allura: kimanin 2 ml / min.
b) Sashi ya dogara da alamu:
Hanyoyin cuta na ciki da na jijiyoyin jini: daga 5 zuwa 25 ml (200-1000 MG kowace rana) a cikin jijiyoyin yau da kullun don makonni biyu, biye da sauyawa zuwa tsarin gudanarwa na kwamfutar hannu.
Cututtukan jiki da cuta kamar su ischemic stroke: 20-50 ml (800 - 2000 MG) a cikin 200-300 ml na 0.9% sodium chloride bayani ko 5% na glucose, narkewa a cikin kullun don mako 1, sannan 10-20 ml (400 - 800 mg) cikin hanzari drip - makonni biyu tare da m canzawa zuwa kwamfutar hannu karbar kudin shiga.
Ciki (na jijiya da jijiyoyin jiki) cuta na jijiyoyin jiki da sakamakon su: 20-30 ml (800 - 1000 MG) na miyagun ƙwayoyi a cikin 200 ml na 0.9% sodium chloride bayani ko 5% maganin glucose, cikin ciki ko cikin cikin kullun, tsawon lokacin magani shine makonni 4.
Kwayar cutar ciwon sukari: 50 ml (2000 mg) a kowace rana cikin makonni 3 tare da m canzawa zuwa kwamfutar hannu tsarin - kwamfutar hannu 2-3 sau 3 a rana don akalla watanni 4-5.
Cutar raunuka daga cikin ƙananan ƙananan: 10 ml (400 mg) a ciki ko 5 ml intramuscularly a rana ko sau 3-4 a mako, gwargwadon tsarin warkarwa
Tsawon lokacin da ake yin magani ana ƙaddara shi daban-daban bisa ga alamu da tsananin cutar.
Umarni na musamman
Intramuscularly, yana da kyau a allura a hankali ba fiye da 5 ml ba, tunda maganin yana maganin hauhawar jini.
Ganin yiwuwar halayen anaphylactic, ana ba da shawarar ayi allurar gwaji (2 ml intramuscularly) kafin a fara maganin.
Amfani da Actovegin® yakamata a gudanar dashi karkashin kulawa ta likitanci, tare da damar da ta dace don maganin halayen rashin lafiyan.
Don amfani da jiko, Actovegin®, allura, za'a iya ƙara shi zuwa maganin isotonic sodium chloride ko kuma maganin glucose 5%. Dole ne a lura da yanayin yanayin damuwa, tunda Actovegin® don allurar ba ta ƙunshi abubuwan adana magani.
Daga ra'ayi na nazarin halittu, bude ampoules da shirye-shiryen da aka shirya ya kamata a yi amfani dasu nan da nan. Dole ne a zubar da magungunan da basuyi amfani da su ba.
Amma game da hada maganin Actovegin® tare da sauran hanyoyin magance allura ko jiko, rashin daidaituwa na kimiyyar lissafi, da ma'amala tsakanin abubuwan da ke aiki, ba za a iya cire su ba, koda kuwa mafita zai kasance a bayyane. Don wannan, ba za a gudanar da maganin Actovegin® a cakuda da wasu magunguna ba, ban da waɗanda aka ambata a cikin umarnin.
Maganin allura yana da farin ruwan kwalliya, gwargwadon ƙarfinsa wanda ya dogara da lambar batir da kayan tushe, duk da haka, launi na mafita baya tasiri tasiri da haƙurin maganin.
Karku yi amfani da maganin opaque ko kuma maganin dake ɗauke da barbashi!
Yi amfani da hankali cikin hyperchloremia, hypernatremia.
A halin yanzu babu bayanan da ke akwai kuma ba a ba da shawarar amfani.
Yi amfani yayin daukar ciki
Amfani da Actovegin® an yarda dashi idan ana tsammanin amfanin warkewar cutar ya wuce haɗarin haɗuwa ga tayin.
Yi amfani da lokacin lactation
Lokacin amfani da miyagun ƙwayoyi a jikin mutum, babu wani mummunan sakamako ga uwa ko jariri da aka bayyana. Ya kamata a yi amfani da Actovegin® lokacin shayarwa ne kawai idan fa'idodin warkewa ya fi ƙarfin haɗarin yaran.
Siffofin tasiri na miyagun ƙwayoyi akan karfin tuka abin hawa ko ƙwararrun haɗari
Babu ko ƙananan sakamako mai yiwuwa.
Yawan abin sama da ya kamata
Babu bayanai game da yiwuwar karɓar ƙarin maganin Actovegin®. Dangane da bayanan magunguna, ba a tsammanin ƙarin sakamako mai illa.
Fom ɗin sakida marufi
Maganin allura 40 MG / ml.
2 da 5 ml na miyagun ƙwayoyi a cikin ampoules gilashi mara launi (nau'in I, Heb. Pharm.) Tare da hutu. 5 ampoules da filastik mai ɗaurin murfin filastik. Ana sanya fakiti 1 ko 5 tare da umarnin yin amfani da shi a cikin kwali. Bayyananniyar kariya ta zagaye amintaccen zane tare da rubutattun bayanan holographic da sarrafa budewa na farko ana shafawa akan kunshin.
Don 2 ampoules na milimita 5 da 5, ana amfani da alamar alamar a saman gilashin ampoule ko kuma alamar da aka yiwa ampoule.
Rijistar Rijistar Rijista
LLC Takeda Pharmaceuticals, Rasha
Kwali da bayarda ingantaccen iko
LLC Takeda Pharmaceuticals, Rasha
Adireshin kungiyar na karbar korafe-korafe daga masu sayen kayayyaki kan ingancin kayayyakin (kayayyaki) a cikin yankin kasar Kazakhstan:
Ofishin wakilin Takeda Osteuropa Holding GmbH (Austria) a Kazakhstan
Formaddamar da tsari da abun da ke ciki
Ingancin sashi na maganin yana rage zubar da jini daga jinin maraƙi a sashi na 40 MG a milliliter na maganin. Hanyar allurar Actovegin an sanya shi cikin ampoules daban-daban da sikari:
- Maganin 400 MG, a cikin kunshin 5 ampoules na 10 ml kowane,
- Maganin 200 MG, a cikin fakitin 5 ampoules na 5 ml kowane,
- Maganin 80 MG, a cikin kunshin 25 ampoules of 2 ml.
Ampoules suna cikin akwati na filastik. Babban sigogi an yi shi da kwali. Ya ƙunshi jerin abubuwan samarwa da lokacin inganci. A cikin akwati na kwali, ban da kwandon shara tare da ampoules, akwai kuma cikakken bayani. Launin mafita yana da launin shuɗi tare da tabarau daban-daban, gwargwadon jerin fitarwa. Colorarfin launi ba ya tasiri da ƙwayar ƙwayar ƙwayar cutar da kuma tasirirsa.
Alamu don amfani
Actovegin za a iya tsara shi don yanayi mai raɗaɗi da yawa. Amfani da shi ya baratacce ga irin waɗannan cututtukan:
- farji domin bugun jini da sauran sakamako bayan shi,
- encephalopathies na asali daban-daban,
- kasawa da aka gani a cikin aikin ɓaraun, na gefe ko jini na jijiya,
- ischemic bugun jini,
- daban-daban craniocerebral raunin da ya faru,
- angiopathies, musamman na asalin masu ciwon sukari,
- radiation, zafi, hasken rana, sunadarai suna ƙone har zuwa digiri 3,
- polyneuropathies na ciwon sukari,
- lalata trophic
- raunuka daban-daban asali da suke da wuya mu bi,
- fata fata,
- matsin lamba wanda ya faru
- lalacewar mumbus membranes da fata, tsokani sakamakon rashi,
- radiation neuropathies.
Sashi da gudanarwa
Don hanyar da ke cikin hanyar gudanarwa, ana iya tsara maganin Actovegin da zai zama ruwan goro ko rafi. Kafin gabatarwa a cikin jijiya, yana da mahimmanci don narke maganin a cikin 0.9% maganin sodium chloride bayani ko cikin maganin glucose 5%. Thearancin izini na Actovegin da aka yarda da shi ya kai 2000 MG na bushewar kwayoyin ta cikin ruwa na 250 ml.
Don gudanarwa na cikin gida, ya kamata a yi amfani da Actovegin a cikin sashi na 5 zuwa 20 a kowace rana.
Yawan lokacin da aka gudanar dashi ba zai wuce 5 ml cikin awanni 24. A wannan yanayin, gabatarwar yayi jinkirin.
Bayan tantance yanayin mai haƙuri, an zaɓi sashi da ake buƙata. Shawarar da aka bada shawarar a farkon farfajiya shine 5 - 10 ml iv ko iv. A wasu ranakun da suka biyo baya, 5 ml na ciki ko a intramuscularly kowace rana ko sau da yawa akan tsawon kwana 7. Abubuwan da ke cikin jijiyar ciki
A cikin mummunan yanayin mai haƙuri, an ba da shawarar a gudanar da Actovegin cikin ƙwayar cuta a cikin kashi 20 zuwa 50 ml kowace rana don kwanaki da yawa har sai yanayin ya inganta.
A cikin yanayin rikice-rikice na yanayin cututtukan cuta da yawa kuma a cikin cututtukan da yanayin zafin ya nuna, ya zama dole a gudanar da Actovegin i / m ko iv a cikin kashi 5 zuwa 20 ml a cikin kwanakin 14 zuwa 17. Zaɓin sashi ne kawai ta hanyar likita!
Idan ya cancanta, shirin da aka shirya, za'a iya tsara maganin a cikin sashi na 2 zuwa 5 a kowace awa 24 ta hanyar gabatarwar cikin tsoka ko jijiya na tsawon mako hudu zuwa shida.
Matsakaicin gudanarwar ya kamata ya zama sau 1 zuwa 3. Wannan adadin ya bambanta dangane da yanayin farkon mai haƙuri.
Lokacin da kake kulawa da marasa lafiya tare da polyneuropathy na masu ciwon sukari, yana da kyau a fara amfani da Actovegin tare da gudanarwa na ciki. Sashi a cikin wannan yanayin shine 2 g kowace rana, hanya ta lura shine kwana 21. A nan gaba, yana da kyawawa don canzawa zuwa nau'in kwamfutar hannu tare da maganin yau da kullun na allunan 2 zuwa 3 na tsawon awanni 24. Hanyar gudanarwa ta wannan hanyar kusan watanni 4 kenan.
Side effects
Dangane da binciken da yawa, masu haƙuri suna haƙuri da haƙuri ta hanyar Actovegin. Ba da daɗewa ba za a iya lura da halayen anaphylactic, bayyanar rashin lafiyar, da rawar jiki anaphylactic. Wasu lokuta irin waɗannan sakamako masu illa na iya bayyana:
- soreness a wurin allurar ko redness na fata,
- ciwon kai. Wani lokacin ana iya kasancewa tare da jin wani lokacin farin ciki, rauni na gaba daya a cikin jiki, bayyanar rawar jiki,
- asarar sani
- bayyanar cututtukan cututtukan jini: amai, gudawa, zafin ciki, tashin zuciya,
- samarin
- fata kwatsam na fata,
- fyaɗe a jiki (urtikaria), itching na fata, fitar ruwa, angioedema,
- hadin gwiwa zafi ko tsoka zafi,
- Acrocyanosis,
- raguwa ko, ba daɗi ba, ƙaruwa a cikin jini,
- tashin hankali a cikin yankin lumbar,
- paresthesia
- m jihar
- choking
- matsalolin numfashi
- wahalar hadiye,
- ciwon makogwaro,
- abin mamakin maƙarƙashiya a cikin kirji,
- ciwon zuciya
- inara yawan alamu,
- ƙara yin gumi.
Allunan Actovegin - umarnin don amfani
Ana ɗaukar Actovegin a baki. Mai haƙuri ya kamata ya sha allunan 1-2 sau uku a rana.Ba sa buƙatar tauna, zaku iya sha da ruwa ko ruwan 'ya'yan itace (kowane ruwa). An bada shawara don amfani da miyagun ƙwayoyi kafin abinci. Aikin magani shine kwanaki 30-45. A cikin marasa lafiya da ciwon sukari na polyneuropathy, ana ba da allunan 2-3 a baki sau 3 / rana. Hanyar shan magani shine watanni 4-5. Matsayin ne daga ƙwararren masanin ilimin halittar jiki ya ƙayyade tsawon adreshin.
Sharuɗɗan sayarwa da ajiya
Za'a iya siye magungunan Actovegin ne kawai ta hanyar takardar sayan magani. Kiyaye magungunan daga isa ga yara da kariya daga haske. Zazzabi a cikin dakin kada ya wuce digiri 25. Samfurin yana da rayuwar shiryayye na shekaru 3.
A miyagun ƙwayoyi yana da yawan analogues. Bayan haka, ba dukkan su bane suke da tasiri iri guda a jikin mutum, kuma tsarin su ba koyaushe yake dace da amino acid da ke jikin mutum ba. Daga cikin analogues ɗin da aka gabatar, babu wasu kwayoyi da za a iya amfani da shi don yaro. Jerin sun hada da Curantil, Dipyridamole da Vero-Trimetazidine:
- An nuna Curantyl don maganin thrombosis, hanawa da lura da kewaya, hanawa na rashin isasshen jini, hauhawar jini. Contraindicated idan bincikar lafiya: m mikocardial infarction, m angina pectoris, arrhythmia mai tsanani, na ciki na ciki, gazawar hanta.
- Ana amfani da Dipyridamole don hana ƙwayoyin jini na jini bayan jini, infarction na myocardial, haɗarin cerebrovascular, da cuta na rayuwa. Contraindications: m harin na angina pectoris, na jijiyoyin jini jijiya atherosclerosis, auka.
- Ana amfani da Vero-trimetazidine don angina pectoris. Contraindications: ciki, rashin haƙuri na mutum zuwa abubuwan da ke cikin miyagun ƙwayoyi.
Farashin allunan Actovegin
Ana iya sikelin analog na Actovegin ko magani na kanta a kantin magani ko kantin kan layi. Saka farashi, sannan a yi oda tare da bayarwa a Moscow ko yankin Moscow. Kuna iya ajiye kasafin kudin ta hanyar saka idanu kan farashin magunguna a yankin da aka zaɓa. Da ke ƙasa akwai tebur na farashin magunguna a cikin magunguna kan layi daban-daban:
Kristina, 28 years old Mahaifiyata tana fama da karancin abinci. Don inganta hawan jini, na sayi Actovegin. A cewar likita, lokacin shan maganin, ana jigilar jini da sauri, hanyoyin farfadowa na nama suna inganta. Mama ta gamsu, ta koma rayuwar da ta gabata na rayuwa. Ina ba da shawarar shi ga kowa da kowa.
Phillip, dan shekara 43. Ni likita ne da ke da shekaru goma sha biyar na kwarewa. Don inganta halayyar marasa lafiya da ke fama da cututtukan kwakwalwa, Ina ba da shawarar Actovegin. Wannan magani yana hanzarta aiwatar da amfani da iskar oxygen, yana ba da gudummawa ga saurin haƙuri. A cewar marasa lafiya, maganin yana aiki da sauri.
Alevtina, ɗan shekara 29 Mahaifina ya kamu da cutar sankara da ciwan fata. Tun daga lokacin yana kwance. Don warkar da ciwon damuwa, mun fara amfani da Actovegin. Dangane da sake dubawa da sakamako, zamu iya cewa miyagun ƙwayoyi suna da tasiri. Likitoci suna magana da gaskiya game da wannan magani, tunda yana taimaka wajan inganta amfani da iskar oxygen ta sel. Farashin ya yarda.
Farashin allurar Actovegin
Actovegin allurar don 2ml, ampoules 5 - 530-570 rubles.
Actovegin allurar don 2ml, ampoules 10 - 750-850 rubles.
Actovegin allurar don 5ml, ampoules 5 - 530-650 rubles.
Actovegin allurar don 5ml, ampoules 10 - 1050-1250 rubles.
Actovegin allurar 10 ml, ampoules 5 - 1040-1200 rubles.