Maninil 5: umarnin don amfani, analogues da sake dubawa, farashin a cikin kantin magunguna na Rasha

Pharmacodynamics Glibenclamide - (1- <4-2- (5-chloro-2-methoxybenzamido) ethylbenzene sulfonyl> -3-cycloxyxylurea) wakili ne na hypoglycemic. Yana rage matakan glucose a cikin jini na jini a cikin marasa lafiya da ke fama da nau'in sukari na II na sukari a cikin masu sa kai da lafiya saboda karuwar insulin insulin ta kwayoyin halittar jiki. Tasirin hypoglycemic na glibenclamide ya dogara da tattarawar glucose a cikin mahallin da ke kewaye da β-sel na tsibirin na pancreatic na Langerhans. Yana hana sakin glucagon ta hanyar ƙwayoyin cells-pancreatic kuma yana da tasirin karin extraccreatic, musamman, yana kara haɓakar hankalin masu karɓar insulin zuwa insulin a cikin ƙananan kyallen, yana haɓaka aikin insulin a matakin mai karɓa kuma yana rage jinkirin karɓar masu karɓa, duk da haka, ba a bincika mahimmancin asibiti na waɗannan abubuwan mamaki ba tukuna.
Pharmacokinetics Bayan gudanar da baki, yana cikin sauri kuma kusan yana ɗaukar hankali. Samun abinci na lokaci daya ba ya da tasiri sosai game da ɗaukar ƙwayar glibenclamide, amma yana iya haifar da raguwa a cikin taro na glibenclamide a cikin jini na jini. Haɗa zuwa albumin plasma - 98%. Cmax a cikin plasma na jini bayan shan 1.75 mg na glibenclamide an samu shi bayan sa'o'i 1-2 kuma yana 100 ng / ml. Bayan sa'o'i 8-10, ƙwaƙwalwar ƙwayar plasma ta ragu, gwargwadon adadin da aka gudanar, ta hanyar 5-10 ng / ml. A cikin hanta, glibenclamide an kusan canza shi zuwa manyan metabolites biyu: 4-trans-hydroxy-glibenclamide da 3-cis-hydroxy-glibenclamide. Dukkanin metabolites an cire su daidai da fitsari da bile a cikin awanni 45-72. T1 / 2 na glibenclamide shine awa 2-5, amma ana iya tsawan sa har zuwa sa'o'i 8-10. Tsawon lokacin aikin, duk da haka, bai dace da T1 / 2 ba. A cikin marasa lafiya da ke fama da aikin hanta, ƙwayar plasma ta yi saurin zama. A cikin gazawar koda, dangane da matsayin karancin aikin koda, raunin metabolites a cikin fitsari yana ƙaruwa diyya. Tare da lalacewa na matsakaici na koda (ƙarancin creatinine - 30 ml / min), ƙarancin cirewa ya kasance ba a canzawa ba, tare da gazawar haɓakar ɗan adam, tarawa mai yiwuwa ne.

Alamu don amfani da maganin Maninil

Mellitus-non-insulin-dogara da ciwon sukari mellitus (nau'in II), idan ba zai yiwu ba don rama raunin ƙwayar cuta ta hanyar bin abincin da ya dace da haɓaka ayyukan jiki kuma idan babu buƙatar maganin insulin. Tare da haɓakar juriya na biyu don glibenclamide, ana iya aiwatar da maganin haɗin gwiwa tare da insulin, duk da haka, yana iya ba shi da fa'ida a kan maganin insulin monotherapy.

Yin amfani da miyagun ƙwayoyi Maninil

Dole ne likita ya wajabta shi kawai don tabbatar da rage cin abincin. Yin dogaro ya dogara da sakamakon binciken matakin glucose a cikin jini da fitsari.
Alkawarin farko da kuma biyo baya. An fara maganin, gwargwadon iko, tare da ƙananan allurai, da farko, ya shafi marasa lafiya tare da haɓakar haɓakar jini da nauyin jiki ≤50 kg. Ana ba da shawarar farawa tare da alƙawarin allunan 1 / 2-1 Maninil 3.5 (1.75-3.5 mg glibenclamide) ko 1/2 kwamfutar hannu Maninil 5 (2.5 mg glibenclamide) 1 lokaci a rana. Ana iya ƙara ƙarfin wannan kashi a hankali tare da tazara daga wasu kwanaki zuwa ga 1 mako, har sai an sami kashi na warkewa. Matsakaicin tasiri mai amfani shine 15 mg / rana (Allunan 3 na Maninil 5) ko 10.5 mg na microlized glibenclamide (Allunan 3 na Maninil 3.5).
Canja wurin haƙuri tare da amfani da wasu magungunan antidiabetic. Canja wuri zuwa ga gudanarwar Maninil 3.5 ana aiwatar da shi sosai kuma yana farawa da 1 / 2-1 Allunan Maninil 3.5 (1.75-3.5 mg na glibenclamide kowace rana).
Yankan zaɓi. A cikin tsofaffi marasa lafiya, marasa lafiya na asthenized ko rashin isasshen abinci mai gina jiki, haka kuma tare da nakasa na koda ko aikin hepatic, kashi na farko da tabbatarwa ya kamata a rage saboda haɗarin cutar ƙwacewar jiki. Bugu da ƙari, tare da raguwa a cikin nauyin jikin mai haƙuri ko tare da canji a salon rayuwa, yakamata a magance batun daidaita sashi.
Haɗuwa da sauran wakilai masu maganin antidi. Ana iya tsara maninil azaman monotherapy ko a hade tare da metformin. A wasu halaye, tare da rashin haƙuri na metformin, ana iya nuna ƙarin amfani da magungunan glitazone (rosiglitazone, pioglitazone). Hakanan za'a iya haɗuwa da Maninil tare da magungunan maganin antidiabetic na baka wanda ba ya motsa sakin insulin endogenous ta reat-sel (guar ko acarbose). Tare da juriya na biyu zuwa glibenclamide (raguwa a cikin samar da insulin a sakamakon raguwar β-sel na tsibirin na Langerhans), ana iya amfani da maganin haɗin gwiwa tare da insulin. Koyaya, tare da cikakken dakatarwar ɓoyewar insulin a cikin jikin, an nuna monotherapy tare da insulin.
Hanyar gudanarwa da tsawon lokacin kulawa. Ana ɗaukar kashi ɗaya na kullun har zuwa Allunan 2 na Maninil ba tare da tauna tare da isasshen adadin ruwa ba (gilashin ruwa 1) sau 1 kowace rana kafin karin kumallo. A mafi girma na yau da kullun, ana bada shawara don raba shi zuwa allurai 2 a cikin rabo na 2: 1 da safe da maraice. Yana da matukar muhimmanci a sha maganin a kowane lokaci a lokaci guda. Lokacin da kuka tsallake shan magani, ba za ku iya shan shi sau biyu a maimakon wanda aka rasa ba. Tsawon lokacin jiyya ya dogara da yanayin cutar. A lokacin jiyya, wajibi ne don saka idanu akan yanayin metabolism a kai a kai.

Contraindications zuwa yin amfani da miyagun ƙwayoyi Maninil

Idan ana buƙatar maganin insulin: insulin-dogara da ciwon sukari mellitus (nau'in I), metabolic acidosis, hyperglycemic precoma and coma, decompensation of metabolic cuta in cututtukan cututtuka da aiki, kazalika da jihar bayan kamanceceniya, cikakkiyar juriya ga glibenclamide a nau'in ciwon sukari na II mellitus.
Sauran contraindications sun haɗa da: lalata hanta mai ƙarfi, gazawar renal tare da tsaftacewar in30 ml / min, hypersensitivity to glibenclamide, Ponso 4R dye ko wasu abubuwan magungunan, da sauran abubuwan da aka samo na maganin sulfonylurea, sulfonamide, diuretics da probenecid, ciki da shayarwa.

Sakamakon sakamako na miyagun ƙwayoyi Maninil

Lokacin da aka kimanta sakamako masu illa, an dauki waɗannan halaye na yawan aukuwar abubuwa azaman tushen: sau da yawa (≥10%), sau da yawa (≤10% da ≥1%), wani lokacin (≤1% da ≥0.1%), da wuya (≤0.1) % da ≥0.01%), da wuya ((0.01% ko ba a san shari'ar ba):
daga gefen metabolism: sau da yawa - karuwa a cikin nauyin jiki, hypoglycemia, wanda zai iya zama mai haɓakawa kuma ya haifar da mummunar cutar ƙwaƙwalwar ƙwayar cuta, wanda ke barazanar rayuwar mai haƙuri. Abubuwan da ke haifar da wannan na iya zama yawan shan ƙwayoyi, ƙwayar hanta da aikin koda, shan giya, rashin abinci mai gina jiki (musamman tsallake abinci), aikin motsa jiki wanda ba shi da yawa, rashin abinci mai narkewa a cikin ƙwayar cuta saboda cututtukan cututtukan ƙwayar thyroid, ƙwaƙwalwar baya da kuma cortex na ciki. Adrenergic bayyanar cututtuka tare da hypoglycemia na iya kasancewa a ɓoye ko mai laushi tare da sannu a hankali haɓaka hypoglycemia, neuropathy na yanki, ko maganin kwantar da hankali tare da juyayi (musamman ckers-adrenergic receptionor blockers). Bayyanar cututtukan dake tattare da cututtukan cututtukan zuciya: hyperhidrosis, palpitations, rawar jiki, jin kaifi na yunwar, damuwa, paresthesia a bakin, pallor na fata, ciwon kai, amai, dysomnia, rashin daidaituwa game da motsi, rikicewar jijiyoyin hankali (magana da wahalar hangen nesa, yanayin motsa jiki da yanayin motsa jiki). ) Don informationarin bayani game da yanayin cutar tarin fuka, duba yawan abin sama da ya kamata. Tare da yin amfani da dogon lokaci, haɓakar hauhawar ƙwayar thyroid mai yiwuwa ne,
a bangare na hangen nesa: da wuya - rashi gani da masauki, musamman a farkon jiyya,
daga jijiyoyin mahaifa: wani lokacin - tashin zuciya, jin cikakken ciki / cika a ciki, amai, jin zafi a ciki, zawo, belching, ƙarfe dandano a bakin. Wadannan canje-canjen na lokaci ne kuma basa buƙatar dakatar da maganin,
daga tsarin hepatobiliary: da wuya sosai - karuwar tazara a cikin ASAT da ALAT, alkaline phosphatase, hepatitis na miyagun ƙwayoyi, ƙwaƙwalwar ƙwayar cuta na intrahepatic, mai yiwuwa ya haifar da rashin lafiyan halayen nau'in hyperergic daga gefen hepatocytes. Wadannan rikice-rikice na iya zama koma baya bayan dakatar da magani, amma na iya haifar da gazawar hanta mai haɗari,
akan sashin fata da kasusuwa na kasa: wani lokacin itching, fitsari, erythema nodosum, corymboid ko maculopapular exanthema, purpura, photoensitivity. Wadannan maganganu na rashin damuwa suna juyawa ne, amma da wuya ka iya haifar da yanayin barazanar rayuwa, tare da gajeriyar numfashi da raguwar hauhawar jini, har zuwa ci gaba da rawar jiki. Da wuya sosai - abubuwanda ke haifar da rikicewar jiki, wanda ke haɗuwa da fitsari na fata, arthralgia, jin sanyi, proteinuria da jaundice, amai da gudawa,
daga tsarin jini da tsarin lymphatic: da wuya - thrombocytopenia, da wuya - leukopenia, erythropenia, granulocytopenia (har zuwa ci gaban agranulocytosis), a wasu yanayi - pancytopenia, hemolytic anemia. Canje-canje da aka jera a cikin hoton jini ana juyawa ne, amma da wuya ka iya zama barazana ga rayuwa,
sauran sakamako masu illa: da wuya - rashin ƙarfi diuretic sakamako, farfadowa proteinuria, hyponatremia, disulfiram-like dauki, giyan rashin lafiyan mutum tare da sulfonamides, abubuwan da ake kira sulfonamide da probenecid. Fenti na Ponso 4R na iya haifar da rashin lafiyan halayen.

Umarnin na musamman don amfanin Maninil na miyagun ƙwayoyi

Maganin Maninil yana buƙatar kulawa da likita na yau da kullun. Lokacin amfani da miyagun ƙwayoyi a cikin babban allurai ko lokacin sake amfani da shi a ɗan gajeren lokaci, ya zama dole yin la'akari da tasirin maganin na tsawon lokaci fiye da lokacin amfani dashi da ƙananan allurai.
Dole ne a tuna cewa tare da amfani da Maninil na lokaci guda tare da clonidine, β-adrenergic blockers, guanethidine da reserpine, tsinkaye mara lafiya na alamun bayyanar cututtukan hypoglycemia na iya lalacewa.
Game da lalacewa na aiki ko aikin hepatic, rage yawan aikin thyroid, glandon gland ko kuma adrenal cortex, ana buƙatar kulawa ta musamman.
A cikin tsofaffi marasa lafiya, akwai haɗarin raɗaɗɗen hypoglycemia, sabili da haka, an wajabta glibenclamide tare da tsananin taka tsantsan kuma a ƙarƙashin kulawa akai akai a farkon jiyya, yana da kyau ku fara ɗaukar shirye-shiryen sulfonylurea tare da taƙaitaccen lokacin aiki. Tare da hulɗa mai wahala tare da mai haƙuri (alal misali, tare da atherosclerosis cerebral), haɗarin haɓakar haɓakar jini yana ƙaruwa. Mahimmancin tsaka-tsaka tsakanin abinci, isasshen adadin carbohydrates da aka cinye, abubuwan da ba a saba gani ba, zawo ko amai na iya haifar da haɗarin hauhawar jini. Alcohol tare da guda ɗaya a cikin babban adadin kuma tare da ci gaba da kullun na iya ƙarfafa kwatsam ko raunana tasirin Maninil. Kullum cin zarafin maye gurbi zai iya haifar da lalacewa a cikin yanayin metabolism. Idan ba a bi tsarin kulawa ba, tare da isasshen sakamako na hypoglycemic na miyagun ƙwayoyi ko yayin yanayi mai damuwa, matakan glucose na jini na iya ƙaruwa. Bayyanar cututtukan hyperglycemia: polydipsia, bushe bushe, yawan urination, itching da bushe fata, fungal ko cututtukan fata na kamuwa da cuta, rage yawan aiki. A cikin yanayi mai raɗaɗi (rauni, tiyata, cuta mai kamuwa da cuta, wanda ke haɗuwa da haɓaka yawan zafin jiki), metabolism na iya ƙaruwa, yana haifar da hauhawar jini, wani lokacin don haka yana iya zama mai mahimmanci don canja wurin mara lafiya zuwa ɗan lokaci zuwa maganin insulin. Ya kamata a sanar da mai haƙuri cewa ya kamata ya sanar da likita nan da nan game da haɓaka wasu cututtuka yayin magani tare da Maninil.
Game da karancin glucose-6-phosphate dehydrogenase, magani tare da shirye-shiryen sulfonylurea, gami da glibenclamide, na iya haifar da cutar haemolytic, sabili da haka ya zama dole yanke shawara game da amfani da wasu hanyoyin da ake amfani da su na maganin sulfonylurea.
Tare da rashin haƙuri na galactose, ƙarancin lactase ko lalacewar glucose / galactose sha, Bai kamata a yi amfani da Maninil ba.
Yi amfani da lokacin daukar ciki da lactation. An hana shi.
Yi amfani da yara. Kar a yi amfani.
Thearfin yin tasiri akan ƙimar amsawa yayin tuki motoci ko aiki tare da injuna. Tare da hypoglycemia, ikon mayar da hankali da saurin amsa na iya raguwa, wanda dole ne a la'akari lokacin tuki motocin da kuma aiki tare da wasu hanyoyin. Wannan yana da mahimmanci musamman a lokuta masu faruwa na yanayin hypoglycemic ko kuma rashin samun cikakkiyar tsinkaye game da alamun bayyanar cututtukan jini, yayin da ya zama dole yanke shawara game da shawarar tuki motocin ko aiki tare da hanyoyin.

Mu'amala da Magunguna Maninil

Gara yawan Glibenclamide (haɓaka yanayin hypoglycemic mai yiwuwa ne) mai yiwuwa ne lokacin da aka yi amfani da su lokaci ɗaya tare da sauran magungunan maganin antidiabetic (metformin da acarbose) da insulin, ACE inhibitors, sitacin anabolic da hormones na maza, maganin antidepressants (fluoxetine, MAO inhibitors), phenylbutazone adrenergic bloading jamiái. quinolone, chloramphenicol, clofibrate da analogs, sabapyramide, fenfluramine, miconazole, PASK, pentoxifylline (tare da gudanarwar parenteral a cikin babban kashi), p ergexilin, abubuwan pyrazolone, probenecid, salicylates, fibrates, sulfonamides, magungunan tetracycline, tritokvalin, cytostatics (cyclophosphamide, ifosfamide, trophosphamide).
Rage sakamako na glibenclamide (haɓaka yanayin yanayi) zai yiwu tare da amfani da lokaci ɗaya tare da acetazolamide, β-adrenoreceptor blockers, barbiturates, diazoxide, chloramphenicol, phenylbutazone, oxyphenbutazone, azopropanone, sulfinpyrazone, miconazole, pheniramidine gluon, gluon phenytoin, rifampicin, hormones na thyroid, kwayoyi na kwayoyin jima'i na mace (gestagens, estrogens), jinƙai.
Masu maganin antagon na H2 masu karɓa zasu iya raunanawa da haɓaka tasirin hypoglycemic da kwayoyi. Barasa giya na iya haɓaka ko rage ƙarfin tasirin cutar glibenclamide.
A cikin wasu halayen, pentamidine na iya haifar da mummunan hypo- ko hyperglycemia. Ayyukan abubuwan asalin coumarin na iya haɓaka da raguwa.
Wakilai na sympatolytic, kamar ckers-adrenergic blockers, reserpine, clonidine da guanethidine, tare da ci gaba da amfani, na iya taimakawa rage matakan glucose na jini da alamun hypoglycemia.

Doaukar yawan magunguna Maninil, alamu da magani

Andaukar cuta mai saurin kamuwa da cuta ta glibenclamide na iya haifar da ci gaba na tsawan rai, tsawan lokaci da kuma barazanar rayuwa. Hypoglycemia na iya haɓakawa saboda tsallake abinci, ƙara yawan aiki na jiki da hulɗa tsakanin kwayoyi.
Bayyanar cututtuka na hypoglycemia: matsananciyar yunwar, tashin zuciya, amai, rauni gaba ɗaya, damuwa, hyperhidrosis, tachycardia, rawar jiki, mydriasis, hauhawar tsoka, ciwon kai, hargitsi na bacci, tashin hankali na endocrine (tashin hankali, tashin hankali, rashin ƙarfi, rashin damuwa na hankali, rikice-rikice, daidaituwa daidaituwa tsofaffin motocin - tsokoki, rikicewar motsi, yin nasara, cramps, alamomin mai da hankali - hemiplegia, aphasia, diplopia, nutsuwa, laima, rauni na tsakiya na tsarin numfashi da aikin jijiyoyin jini. sudistoy tsarin). Tare da ci gaban hypoglycemia, asarar sani (hypoglycemic coma) mai yiwuwa ne, halin rigar sanyi da fata yayin bugun jini, tachycardia, hauhawar jini, tashin hankali, hauhawar jini, bayyanar ingantacciyar farfadowa ta Babinsky da haɓakar paresis da seizures.
Jiyya. Rashin daidaituwa na hypoglycemia (ba tare da asarar hankali ba), mai haƙuri yana da ikon kawar da kansa, yana ɗaukar kusan 20 g na glucose, sukari ko abinci mai carbohydrate.
Idan bazata wuce haddi ba kuma a gaban saduwa da mai haƙuri, ya zama dole a sanya amai, aiwatar da yanayin motsa jiki (in babu shiri mai ƙarfi), sanya adsorbents da allurar maganin glucose. A cikin babban rauni na jini (tare da asarar hankali), ya kamata a yi catheterization na jijiya nan da nan. Cikin nutsuwa, ana gudanar da maganin 40-100 na 40% na glucose, ana iya bibiya da kashi 5-10% na glucose, kuma idan kwayar cutar catinterization bazai yuwu ba, i / m ko s / c 1-2 mg glucagon. Idan mai haƙuri bai sake dawowa da hankali ba, ana maimaita matakan da ke sama, idan ya cancanta, ana gudanar da jiyya mai zurfi. Don rigakafin sake dawowa daga cututtukan hypoglycemia bayan murmurewa na tsawon sa'o'i 24 zuwa 48 na gaba, ana wajabta sinadarin carbohydrates a cikin (20-30 g nan da nan da kowane sa'o'i 2-3) ko kuma ana bayar da cigaban iv na 5-20% na glucose. Kuna iya shigarwa tsawon awanni 48 a kowane 6 na awo 1 na glucagon / m. Ana kula da cutar ta glycemia aƙalla awanni 48 bayan cirewar cutar sikari. Idan hankali bai murmure tare da yawan zubar da ruwa ba (alal misali, tare da yunƙurin kashe kansa), ana yin cigaban maganin glucose 5-10%, ƙwaƙwalwar ƙwayar plasma da ake so shine kimanin 200 mg / dl. Bayan minti 20, sake sakewa da 40% na glucose bayani yana yiwuwa. Idan hoto na asibiti ba ya canzawa, ya zama dole a gudanar da bambance-bambancen ganewar asali na coma, kuma a lokaci guda gudanar da jiyya don cututtukan cerebral edema (dexamethasone, sorbitol). Glibenclamide ba a ɓoye lokacin hemodialysis ba.

Umarnin don amfani

Shan Maninil, kamar kowane ƙwayar cututtukan ƙwayar cuta, kuna buƙatar bin abinci.

Maninil magani ne mai araha wanda Berlin-Chemie AG / Menarini Group (Jamus) suka kirkira. Hakanan rajistarsa ​​ana shigo dashi na Glimidstad wanda kamfanin Arzneimittel AG (Jamus) yayi rajista. Ba zai yiwu a sami wannan magani a cikin kantin magunguna ba a lokacin rubuce-rubuce.

Allunan na glibenclamide suna samarwa ta hanyar masana'antun gida a cikin kasashen CIS, alal misali, Atoll LLC (Russia). Magungunan Jamusanci na asali Maninil ba shi da tsada. Babu wata ma'ana a cikin sauyawa zuwa koda analogues mai rahusa. Lura cewa wannan magani yana cikin jerin magungunan cutarwa ga masu ciwon sukari na 2. Sabili da haka, ya fi kyau a ƙi ɗaukar kowane kwamfutar hannu wanda kayan aiki masu aiki suna glibenclamide.

Wanne Maninil ne yafi kyau? Menene ma'aunin yau da kullun shine 1.75, 3.5 ko 5 mg?

Wannan magani ne mai cutarwa, ba tare da la'akari da sashi ba wanda zaku sha shi. Koyaya, yayin da aka fara amfani da sashi, da sannu cikakkiyar cikakkiyar ƙwayar cuta ta farji zata faru, kuma nau'in ciwon sukari na 2 zai juya zuwa matsanancin ciwon sukari na 1. Karanta labarin “Kwayoyin Cututtuka masu Cutar Cutar Ciwon Ciki: Jerin” don ƙarin bayani. Kwayoyin kwayoyi masu arha da aka yi a Rasha da kasashen CIS na iya zama mafi muni har da asalin magungunan da aka shigo da su.

Yadda ake ɗaukar Maninil

Umarni ya bada shawarar shan Maninil sau 2 a rana - safe da maraice, kafin abinci, tare da ruwa. Allunan za'a iya raba su rabi, amma ba za a iya tauna ba. Ana amfani da maganin da ya dace da likitan ya bayar. Marasa lafiya masu ciwon sukari ba za su iya yin wannan da kansu ba, saboda idan kayi kuskure tare da kashi, ana iya samun mummunar illa. Bayan shan magani, tabbas za ku ci, don kada sukarin jini ya ragu da yawa.

Yawancin marasa lafiya suna sha'awar menene mafi girman adadin yau da kullun na glibenclamide. Koyaya, yunƙurin ƙara yawan sarkar da wannan ƙwayar cuta koyaushe yana kawo illa kawai. Idan glibenclamide a cikin ƙarami ko matsakaici ya dakatar da rage yawan sukarin ku, kuna buƙatar canzawa don injections na insulin. Karanta nan dalilin da yasa Maninil mummunan magani ne kuma dakatar da shan shi. Koyi yadda ake runtse sukari na jini da tabbatar dashi a al'ada ba tare da shan magungunan cutarwa ba.

Maninil ko Diabeton: Wanne ya fi? Zan iya ɗauka a lokaci guda?

Maninil da Diabeton magunguna ne masu cutarwa. Zai fi kyau a daina amfani da kowane ɗayansu don bi da ciwon sukari na 2. Karanta nan dalla dalla dalla game da illar da suka kawo da abin da zaku iya maye gurbinsu. Maninil da Diabeton sun ƙunshi abubuwa daban-daban na aiki, amma an haɗa su a rukuni guda na sulfonylureas. Duk magungunan da suka fada cikin wannan rukunin suna da ƙanƙantar da sukari na jini, amma kada ku rage mutuwar masu haƙuri, amma a'a har ma da ƙara shi.

Allunan aiki Diabeton MV, waɗanda aka ba da shawarar su sha sau ɗaya a rana, ba su da haɗari fiye da Maninil, wanda dole ne a dauki sau 2 a rana. Amma wannan baya nufin cewa kuna buƙatar canzawa daga glibenclamide zuwa Diabeton MV. Yi amfani da tsari ta hanyar mataki-mataki na kamuwa da cutar siga 2, wanda baya buƙatar kowace cuta mai cutarwa ko tsada.

Maninil ko Glucophage: Wanne ya fi kyau?

Maninil yana cikin jerin magunguna masu cutarwa ga masu ciwon sukari na 2. Daga liyafar tasa ya kamata a yi watsi da sauri. Glucophage (metformin) - akasin haka, kayan aiki ne masu amfani har ma da mahimmanci. Bawai kawai yana rage sukarin jini ba, amma yana rage jinkirin ci gaban cututtukan cututtukan zuciya, da rage haɗarin mutuwa daga bugun zuciya da sauran dalilai.

Shafin yanar gizon endocrin-patient.com yana ba da shawarar ɗaukar ainihin maganin da aka shigo da shi Glucofage. Yana da kyau kada a sauya daga gare shi zuwa ga katunan metformin waɗanda ke cikin gida masu arha. Idan kuna da matsaloli tare da sukari da safe a kan komai a ciki, kula da magani Glucofage Long.

Yadda ake ɗaukar metformin da maninil a lokaci guda?

Kada a dauki Metformin da Maninil a lokaci guda. Yakamata a bar Metformin a tsarin kulawar cututtukan cututtukan cututtukan nau'ikan 2 ku, kuma yakamata a cire glibenclamide da sauri. Daga cikin shirye-shiryen metformin, mafi kyawun zaɓi shine magani na asali da aka shigo dashi, Glucofage. Allunan Siofor suna cikin tsananin buƙata. Wataƙila, suna yin rauni kaɗan fiye da Glucofage, amma sun taimaka sosai. Shafin endocrin-patient.com baya bada shawarar daukar shirye-shiryen metformin da aka yi a Rasha da kasashen CIS.

Abin da za a yi idan Maninil bai taimaka ba, baya rage sukarin jini? Yadda za a maye gurbin shi?

Maninil baya rage sukarin jini a cikin waɗancan lokacin da ƙwaƙwalwar mai haƙuri ta daina fitar da insulin. Wannan yana nufin cewa cutar ta juya zuwa mummunan nau'in 1 ciwon sukari. Amincewa da glibenclamide da sauran ƙwayoyi masu cutarwa suna haifar da irin wannan ci gaban baƙin ciki na abubuwan da suka faru a cikin marasa lafiya tare da T2DM. A cikin mawuyacin hali, babu allunan taimako. Kuna buƙatar hanzarta fara allurar insulin, in ba haka ba mai haƙuri na iya faɗi cikin rashin lafiya kuma ya mutu. Zai zama da wahala sosai don dakatar da ci gaban rikitarwa, duk da amfanin insulin.

Ra'ayoyi game da wannan magani

Maganin da aka shigo da shi Maninil ba shi da tsada. Saboda haka, yawancin marasa lafiya da ke da nau'in ciwon sukari na 2 suna zaɓar wannan magani, kuma ba Diabeton MV da Allunan Allunan da ke takara da shi ba. Idan mutane da yawa suna shan maganin, to za a iya samun cikakken bayani game da tasirin tasirinsa a kan lokaci. A rukunin yanar gizon da ke amfani da harshen Rashanci zaka iya samun sake dubawa masu yawa game da masu cutar siga game da ƙwayar Maninil. A yawancin su, marasa lafiya suna korafi cewa bayan shekaru da yawa na shan glibenclamide ya daina taimakawa. A farkon jiyya, yana rage sukari na jini, amma daga baya ya rasa tasiri.

Wannan na halitta ne saboda glibenclamide yana yanke ƙwayoyin koda. A ƙarƙashin tasirin wannan ƙwayar, T2DM na shekaru 4-10 ya wuce cikin nau'in ciwon sukari mai tsanani 1. Maninil da kowane magunguna sun daina taimakawa. Marasa lafiya ba shi da wani zaɓi face ya saka allurar cikin allurai. Zai zama da wuya a dakatar da ci gaban cututtukan cututtukan cututtukan zuciya.

Lokacin karanta kyakkyawan bita game da Maninil, kada ku yarda da su. Saboda mutane ne suka rubuta su wanda kwanan nan suka fara shan maganin. Bayan shekaru da yawa na shiga, ra'ayin masu ciwon sukari game da ƙwayar glibenclamide yawanci yana canzawa. Amma ya yi latti. Rushewar pancreatic ba za'a iya juyawa ba. Shafin yanar gizon endocrin-patient.com ya ba da shawarar yin amfani da tsarin-mataki-mataki-mataki na kula da cutar suga guda biyu maimakon shan magunguna masu cutarwa. Tana da inganci kuma tana cikin lafiya.

8 ra'ayoyi akan Maninil

Sannu Kuna da shafin sabon abu da ban sha'awa. Ina fatan ba da shawara a kan rashin lafiyata. Ni mai shekara 59 ne, tsayi 169 cm, nauyi 87 kg, Na yi rashin lafiya tare da nau'in ciwon sukari na 2 aƙalla shekaru 8. Duk waɗannan shekarun da ta kwashe Maninil a 3.5 mg 2 sau a rana. Godiya ga kwayoyi, sukari koyaushe yana cikin iyakoki na al'ada, wanda ba ya fin girma da 6.5. Amma fiye da watanni 3, alamomi da safe a kan komai a ciki ya karu zuwa 6.5-7.5. Na fara binciken Intanet, na gano rukunin yanar gizonku kuma na canza zuwa rage cin abinci mai karas. Na kuma soke Maninil, Na dauki Glucophage 850 MG sau 3 a rana maimakon. Duk da wannan, sukari baya komawa al'ada. Da safe yana kusan 6.8. Sannan awa daya bayan cin kusan 8.2. Bayan sa'o'i 2 - a cikin yankin na 7.5-8.0. Baya ga ciwon sukari, akwai kuma hauhawar jini, wanda nake sarrafawa tare da taimakon magunguna masu hade. Ina tafiya kan matsakaita tsawon kilomita 10 a sati, ayi motsa jiki a safiyar asuba. Ta yaya zan iya dawo da sukari bisa al'ada ba tare da insulin ba? Ko kuwa latti ne?

Na fara binciken Intanet, na gano rukunin yanar gizonku kuma na canza zuwa rage cin abinci mai karas. Haka kuma an soke Maninil,

Gara daga baya fiye da koyaushe

Ta yaya zan iya dawo da sukari bisa al'ada ba tare da insulin ba? Ko kuwa latti ne?

Kuna rubuta cewa kun kwashe shekaru 8 kuna shan Maninil, ta hanyar fitar da ƙwayar kullen ku da wannan ƙwayar cuta.

Kyakkyawan lokaci na rana! Mahaifiyata, shekara 69, mai ciwon sukari ce da hauhawar jini tare da gogewa mai tsawo. Tsayinta da nauyinta Ban sani ba, amma cikakke ne. Yana karɓar mannin don ciwon sukari, da bisoprolol, valsartan, physiotens, amlodipine, har ma da cardiomagnyl kuma wani lokacin zylt (clopidogrel) don hawan jini. Kimanin kwanaki 10 da suka gabata, sukari ya fara tashi zuwa 10-15 kuma a lokaci guda rikice rikicewar jini ya fara daya bayan juna. Babu shakka, manniline ya daina aiki. Tambaya: Shin rikice-rikicen hawan jini yana da alaƙa da wannan ma?

Babu shakka maninil ya daina aiki

Gaskiya ne. Cutar da gaske ta zama nau'in 1 na ciwon sukari saboda tsawan magani mara kyau. Uwarku cikin gaggawa tana buƙatar fara allurar insulin, in ba haka ba tana iya shiga cikin cutar rashin lafiyar masu fama da cutar siga.

Tambaya: Shin rikice-rikicen hawan jini yana da alaƙa da wannan ma?

Wannan tambaya ce ta falsafa wanda baza'a iya amsa ta daidai ba. Kuma baya tasiri kan hanyoyin magani. Yadda za a sarrafa nau'in ciwon sukari na 2 an bayyana haka - http://endocrin-patient.com/lechenie-diabeta-2-tipa/. Wannan tsarin yana ba da matsayin glucose kawai a cikin jini, amma har da karfin jini.

Yana karɓar mannin don ciwon sukari, da bisoprolol, valsartan, physiotens, amlodipine, har ma da cardiomagnyl kuma wani lokacin zylt (clopidogrel) don hawan jini.

Don bayaninka, cardiomagnyl da sauran allunan asfirin suna da shawarar a sha kawai don rigakafin sake bugun zuciya, amma ba na farko ba. Don ba da umarnin clopidogrel (sylt), dole ne a sami kyakkyawan dalili, sakamakon gwajin jini mara kyau, yana nuna haɗarin haɗarin ƙwanƙwasa jini. Shin mahaifiyarka ta sami wannan gwajin? Sauran magungunan da ke cikin jerin ku sun fi ko mara aminci.

Kuna iya shan magungunan hannu a kullun, amma wannan baya maye gurbin kiyaye ingantaccen tsarin rayuwa.

Sannu Ina da irin wannan takamaiman tambaya. Ina da nau'in ciwon sukari na 2 kwanan nan. Masanin ilimin endocrinologist ya ba da izinin glibenclamide kawai - Maninil ko wasu daga analogues. Dogara mai karfi ta dauki Siofor ko Glyukofazh. Yana mai cewa wannan maganin (metformin) a cikin maganata bai dace ba saboda raunin cutar koda. Gaskiyar ita ce nau'in ciwon sukari na 2 wanda aka haɓaka bayan cututtukan fata. Shin nadin likitan daidai ne?

Shin nadin likitan daidai ne?

Wannan tambaya ce ta falsafa. Idan metformin bai dace da kai ba, to glibenclamide ya fi haka.

Gaskiyar ita ce nau'in ciwon sukari na 2 wanda aka haɓaka bayan cututtukan fata.

Ga tsarin kulawa da cutar sankara, dangane da karancin abinci mai karko - http://endocrin-patient.com/lechenie-diabeta-2-tipa/. Cututtukan ƙwayar cuta na yau da kullun ba shine contraindication bane bisa ƙa'ida! Ana amfani da wannan tsarin cikin nasara ta hanyar yawancin marasa lafiya da ke fama da wannan cuta. Kuna buƙatar ƙi 100% na soyayyen (ƙonawa) da kyafaffen abinci, kazalika da ɗanɗano abinci, a hankali, kada ku ci cikin sauri. Kokarin kada ku ci kowane irin abincin da aka sarrafa kwatankwacinsu, dafa abinci lafiyayye da kanku. Amma game da barasa - shi ne mutum.

Sannu, Sergey. Mahaifiyata tana da shekara 59, tsayi 167 cm, nauyi 79 kg. Tana dauke da cutar sukari na 2. A cikin magunguna, Maninil 500 MG sau biyu a rana. Tana bin abincin, Ina bin wannan da kaina. Damuwa game da surges a cikin sukari, musamman lokacin da juyayi. Ba sau da yawa, amma yana faruwa cewa ya hau zuwa 11-12, kuma sosai. Daga irin wannan tsinkaye, kamar yadda na fahimta, masan ilimin kimiyyar halittar dabbobi ya tsara mata Dibicor. Ta ɗan shafe mako guda tana shan shi, sugar yanzu kamar tana kan matakin ɗaya, amma kuma ta sake tsalle. Wataƙila yana da ma'ana a haɗu da wasu magunguna?

Wataƙila yana da ma'ana a haɗu da wasu magunguna?

Da farko dai, kuna buƙatar bincika labaran a hankali akan wannan rukunin yanar gizon, sannan kuyi sharhi, kuyi tambayoyi masu hankali.

the endocrinologist ya wajabta mata Dibicor

Alamu don amfani

Menene taimaka Maninil 5? Dangane da umarnin, an wajabta magungunan a cikin halaye masu zuwa:

• Nau'in 2 na ciwon sukari mellitus - a matsayin monotherapy ko kuma wani ɓangare na maganin haɗin gwiwa tare da sauran magungunan maganganu na baka, sai dai maganin sulfonylureas da amo.

Analogs Maninil 5, farashin a cikin kantin magani

Idan ya cancanta, zaku iya maye gurbin Maninil 5 tare da analog don abu mai aiki - waɗannan magunguna ne:

1. Gilemal
2. Glibamide
3. Glibenclamide,
4. Glidanil
5. Glimidstad
6. Glitisol
7. Glucobene,
8. Daonil
9. Maniglide
10. Euglucon.

Lokacin zabar analogues, yana da mahimmanci a fahimci cewa umarnin don amfani da Maninil 5, farashi da sake dubawa, ba su shafi magunguna masu tasiri ba. Yana da mahimmanci don samun shawarar likita kuma kada kuyi canjin magani mai yanci.

Farashi a cikin kantin magunguna na Rasha: Maninil 5 120 Allunan - daga 77 zuwa 135 rubles, bisa ga magunguna 683.

Kada a kula da yara a yanayin zafi har zuwa 25 ° C. Rayuwar shelf shine shekaru 3.

Yanayin bayarda magunguna daga magunguna magani ne.

Nazarin game da amfanin Maninil 5 galibi tabbatacce ne. Mutanen da ke shan maganin da likitoci suna lura da babban tasirin maganin. A cikin sake dubawa akwai rahotanni game da ci gaban halayen masu illa a cikin nau'i na amai da ƙwaya - wannan na iya zama saboda ƙarancin maganin.