Losartan: umarnin don amfani

A cikin wannan labarin, zaku iya karanta umarnin don amfani da miyagun ƙwayoyi Losartan. Yana ba da ra'ayi daga baƙi zuwa shafin - masu amfani da wannan magani, kazalika da ra'ayoyin kwararrun likitocin game da amfani da Losartan a cikin al'amuran su. Babban buƙatar shine a ƙara ra'ayoyinku game da miyagun ƙwayoyi: maganin ya taimaka ko bai taimaka kawar da cutar ba, menene rikice-rikice da sakamako masu illa da aka lura, mai yiwuwa ba sanar da mai masana'anta a cikin bayanin ba. Analogs na Losartan a gaban tsoffin tsarin analogues. Amfani don lura da hauhawar jini da rage karfin jini a cikin manya, yara, harda lokacin daukar ciki da lactation.

Losartan - wakili na antihypertensive. Yana da ba mai peptide angiotensin mai karɓa mai karɓa ba 2. Yana da babban zaɓi da kuma kusanci ga masu karɓar AT1 (tare da haɗuwa wanda babban tasirin angiotensin 2 ya tabbata). Ta hanyar toshe waɗannan masu karɓar, losartan yana hanawa kuma yana kawar da sakamako na vasoconstrictive na angiotensin 2, tasirin ta mai motsa jiki akan narkewar aldosterone ta glandon adrenal da wasu tasirin angiotensin 2. An bayyana shi ta hanyar sakamako na tsawon lokaci (awanni 24 ko sama da haka), saboda ƙirƙirar metabolite mai aiki.

Abun ciki

Potassium Losartan + magabata.

Pharmacokinetics

Bayan gudanar da baki, losartan yana saurin narkewa daga narkewa. Bioavailability kusan kashi 33%. An metabolized a lokacin "hanyar farko" ta hanta tare da kirkirar metabolite carboxyl, wanda ke da ƙwaƙwalwar motsa jiki fiye da losartan, da kuma yawan metabolites marasa aiki. Dogara ga ƙwayoyin plasma na losartan da metabolite mai aiki suna da girma - fiye da 98%. Losartan an keɓe shi a cikin fitsari da feces (tare da bile) ba canzawa kuma a cikin hanyar metabolites. Kusan 35% an fesa a cikin fitsari kuma kusan 60% - tare da feces.

Alamu

• hauhawar jini
• raguwa a cikin hadarin haɗarin cututtukan zuciya da mace-mace a cikin marasa lafiya tare da hauhawar jini da jijiyoyin jini na hagu, wanda aka nuna da raguwa a haɗewar yawan cututtukan zuciya, da yawan bugun jini da rarrabuwa myocardial,
• kariya daga koda a cikin marasa lafiya da ke da nau'in ciwon sukari na 2 na sukurku tare da proteinuria - raguwa a cikin ci gaba da rashin cin nasara na koda, bayyanar da raguwar yawan cututtukan hypercreatininemia, abubuwan da suka faru na ƙarancin lalacewa na lalacewa, suna buƙatar hemodialysis ko jigilar koda, yawan mace-mace, kazalika da raguwar furotin,
• rauni na zuciya tare da gazawar magani daga masu hana ACE.

Sakin Fom

Allunan da aka rufe 12.5 mg, 25 MG, 50 MG da MG 100 (wanda aka samar da Richter, Teva, H form tare da diuretic hydrochlorothiazide).

Umarnin don amfani da sashi

Ana amfani da losartan na miyagun ƙwayoyi ta baka, ba tare da la'akari da abincin ba. Allunan an cinye su ba tare da taunawa ba, an wanke su da ruwa. Maimaitawa da yawa - sau 1 a rana.

Tare da hauhawar jini, matsakaicin yawan yau da kullun shine 50 MG 1 lokaci ɗaya kowace rana. Don cimma sakamako mafi girma na warkewa, ana kara kashi zuwa 100 MG kowace rana.

Rashin lafiyar zuciya

Maganin farko ga marasa lafiya da raunin zuciya shine 12.5 MG sau ɗaya a rana. A matsayinka na mai mulkin, kashi yana ƙaruwa tare da tazara ta mako-mako (i.e. 12.5 mg a kowace rana, 25 MG kowace rana da 50 MG a kowace rana) zuwa matsakaiciyar kiyayewa na 50 MG 1 lokaci ɗaya kowace rana, gwargwadon haƙuri da haƙuri ga miyagun ƙwayoyi.

Babu buƙatar daidaituwa na kashi a cikin marasa lafiya tsofaffi.

Rage haɗarin ci gaba, cututtukan zuciya (ciki har da bugun jini) da mace-mace a cikin marasa lafiya da hauhawar jijiya da hauhawar jini ventricular hagu

Maganin farko na maganin shine 50 MG 1 lokaci ɗaya kowace rana. A nan gaba, ana iya ƙara hydrochlorothiazide a cikin ƙananan allurai ko kuma za a iya ƙara yawan Losartan zuwa 100 MG a cikin 1 ko allurai, la'akari da raguwar hauhawar jini.

Marasa lafiya da ke dauke da nau'in ciwon sukari iri 2 tare da proteinuria

An tsara miyagun ƙwayoyi a cikin kashi na farko na 50 MG sau ɗaya a rana tare da ƙarin karuwa a kashi zuwa 100 MG kowace rana (yin la'akari da matakin rage karfin jini) a cikin ɗaya ko biyu allurai.

A cikin marasa lafiya da rage yawan BCC (alal misali, lokacin ɗaukar diuretics a cikin manyan allurai), shawarar da aka fara bayarwa ta Losartan shine 25 MG sau ɗaya a rana.

Marasa lafiya tare da rashin wadataccen hepatic (ƙasa da maki 9 akan sikelin Yara-Pugh), yayin aikin hemodialysis, kazalika da marasa lafiya sama da shekaru 75, ana bada shawarar ƙaramin maganin farko na maganin - 25 mg sau ɗaya a rana.

Babu isasshen gogewa game da amfani da miyagun ƙwayoyi a cikin marasa lafiya da gazawar hanta mai ƙarfi, sabili da haka, ba a ba da shawarar maganin a cikin wannan rukuni na marasa lafiya.

A miyagun ƙwayoyi ba shi da peculiarities na aiki a farkon kashi ko lokacin da aka soke, amma kula da karfin jini ya zama dole kamar yadda yake tare da kowace irin ƙwayar cuta.

Amincewa da magungunan antihypertensive yakamata a gudanar dasu a lokaci guda da aka wajabta akan shawarar likita don kara tasirin warkewa. Idan kun tsallake shan magani ɗaya, kuna buƙatar ɗaukar kashi na gaba na miyagun ƙwayoyi a lokacin da yake kusa da lokacin da aka saba shan magunguna ko kuma lokacin da kuka tuna cewa kun rasa kashi ɗin ta hanyar motsa lokacin na gaba. Kada ku ɗauki kashi biyu na magani.

Side sakamako

• tsananin farin ciki
• asthenia / gajiya,
• ciwon kai
• rashin bacci
• damuwa
• tashin hankali na bacci
• nutsuwa
• ƙwaƙwalwar ƙwaƙwalwar ajiya
• na gefe neuropathies,
• paresthesia
• migraine
• rawar jiki
• bacin rai
• kunne a cikin kunnuwa
• ku ɗanɗani cin zarafi
• hangen nesa
• alaƙa
• hanci
• tari
• babba na numfashi fili cututtuka (zazzabi, ciwon makogwaro),
• sinusitis
• pharyngitis
• rhinitis
• tashin zuciya, amai,
• zawo
• abubuwan dyspeptik
• ciwon ciki
• bushe mucosa na baka,
• anorexia
• katsewa
• myalgia
• jin zafi a baya, kirji, kafafu,
• arthralgia,
• tachy ko bradycardia,
• arrhythmias
• angina pectoris
• anemia
• infarction na zuciya
• tura zuwa urinate
• rage libido
• rashin ƙarfi
• bushe fata
• kara jini
• daukar hoto,
• ƙara yin gumi
• alopecia
• cututtukan mahaifa
• fata fitsari
• itching
• angioedema, gami da fuska, lebe, pharynx da / ko harshe,
• zazzabi
• gout
• vasculitis
• eosinophilia
• purpura Shenlein-Genoch.

Contraindications

• ciki
• lactation
• shekaru zuwa shekaru 18
• matsanancin hanta (fiye da maki 9 akan sikelin-Yara),,
• rashin haƙuri na galactose rashin haƙuri, rashi lactase ko cutar glucose-galactose malabsorption syndrome,
• rashin hankali ga abubuwan da ke cikin miyagun ƙwayoyi.

Haihuwa da lactation

Yin amfani da miyagun ƙwayoyi losartan lokacin daukar ciki yana contraindicated. An san cewa kwayoyi da suka shafi tsarin renin-angiotensin-aldosterone kai tsaye (RAAS), lokacin da aka yi amfani da su a cikin kashi na 2 da na 3 na ciki, na iya haifar da lahani na haɓaka ko ma mutuwar tayi. Sabili da haka, lokacin da ake bincika ciki, ya kamata a dakatar da Losartan nan da nan.

Ba a sani ba ko losartan tare da madara mai nono keɓe. Ba'a ba da shawarar shan ƙwayar miyagun ƙwayoyi a lokacin lactation. Idan shan Losartan ya zama dole yayin lactation, to dole ne a dakatar da shan mama.

Yi amfani da shi a cikin tsofaffi marasa lafiya

Babu buƙatar daidaituwa na kashi a cikin marasa lafiya tsofaffi.

Ana ba da shawarar marasa lafiya da suka wuce shekaru 75 da keɓaɓɓen kashi na farko na maganin - 25 MG sau ɗaya a rana.

Yi amfani da yara

Contraindicated a cikin yara da matasa a karkashin shekara 18.

Umarni na musamman

Ga marasa lafiya da raunin zuciya wanda aka samu sakamako mai ƙoshin lafiya sakamakon amfani da masu hana ACE, ba a bada shawara don canzawa zuwa ɗaukar angiotensin 2 masu adawa da karɓa, ciki har da miyagun ƙwayoyi losartan.

Marasa lafiya tare da ilimin hanta (ƙasa da maki 9 akan sikelin Chaydd-Pugh, kuma musamman tare da cirrhosis), gami da A cikin ananesis, ya zama dole a nada kananan allurai.

A cikin marasa lafiya masu fama da rashin ruwa (misali, karbar magani tare da allurai na diuretics), hypotension hypotension na iya faruwa a farkon fara amfani da losartan (ya zama dole a gyara bushewar fata kafin a rubuta losartan ko a fara jiyya tare da ƙananan kasala).

Marasa lafiya tare da rauni na aiki na koda, duka tare da kuma ba tare da ciwon sukari ba, sau da yawa suna haifar da rikicewar lantarki (hyperkalemia), wanda ya kamata a magance shi. A gaban m ko na koda na kasawa, losartan na iya haifar da nakasa aiki na koda tare da ko ba tare da hyperkalemia ba.

Yayin yin jiyya tare da losartan, ya kamata a sa ido a kan matakan potassium a cikin jini akai-akai, musamman a cikin tsofaffi marasa lafiya kuma tare da raunin aiki na yara. Ya kamata a guji yin amfani da losartan tare da daskararren potassium.

A cikin tsofaffi marasa lafiya amfani da marasa steroidal anti-mai kumburi magunguna, tare da lokaci guda yin amfani da diuretics, ko tare da nakasa aiki na koda, da amfani da losartan zai iya haifar da lalacewa aiki na renal, ciki har da yiwuwar m renal gazawar. Wadannan illolin yawanci ana iya juyawa dasu. Wajibi ne a kula da aikin na lokaci-lokaci a cikin marasa lafiya da ke shan losartan da magungunan anti-inflammatory marasa steroidal.

Bayanai kan aminci da tasirin magani a cikin yara bai isa ba.

Tasiri kan ikon tuka motoci da hanyoyin sarrafa abubuwa

Ba a yi nazarin ikon miyagun ƙwayoyi don yin tasirin hanzarin halayen psychomotor da ikon tuki motoci ko wasu hanyoyin fasaha ba. Yakamata a yi taka tsantsan yayin aiwatar da abubuwa masu haɗari waɗanda ke buƙatar ƙara kulawa da saurin tunani.

Hulɗa da ƙwayoyi

Ana iya amfani da magungunan losartan a lokaci guda tare da sauran magungunan antihypertensive.

Mutually inganta tasirin beta-blockers da tausayawa.

Haɗewar amfani da losartan tare da diuretics yana haifar da sakamako mai ƙari.

Babu hulɗa na pharmacokinetic na losartan tare da hydrochlorothiazide, digoxin, warfarin, cimetidine, phenobarbital, ketoconazole da erythromycin da aka lura.

An ruwaito Rifampicin da fluconazole don rage yawan ƙwayar mai aiki a cikin jini na jini. Har yanzu ba'a san mahimmancin asibiti na waɗannan hulɗa ba.

Kamar yadda yake tare da sauran jami'ai waɗanda ke hana angiotensin ko tasirin sa, haɗuwa da amfani da losartan tare da daskararren-potassium (misali, spironolactone, triamteren, amiloride), shirye-shiryen potassium, da kuma gishiri wanda ke dauke da potassium yana kara haɗarin cutar hyperkalemia.

Magungunan anti-inflammatory Nonsteroidal (NSAIDs), gami da masu hana cyclooxygenase-2 inhibitors (COX-2), na iya rage tasirin diuretics da sauran magungunan antihypertensive.

Tare da haɗin gwiwar angiotensin 2 da antagonists mai karɓa na lithium, haɓakar ƙwaƙwalwar ƙwayar plasma yana yiwuwa. Ganin wannan, ya zama dole a auna fa'ida da kuma haɗarin haɗakar hadin gwiwar losartan tare da gishirin lithium. Idan ya cancanta, haɗin gwiwa na amfani da kwayoyi, ya zama dole don saka idanu a kai a kai game da yawan ɗorawar lithium a cikin jini.

Analogs na miyagun ƙwayoyi Losartan

Tsarin analogues na mai aiki abu:

• Bugawa
• Brozaar
• Vasotens,
• Vero Losartan
• Zisakar
• Cardomin Sanovel,
• Karzartan
• Cozaar
• Lakea
• Lozap,
• Lozarel
• Losartan kannanan,
• Losartan Richter,
• Losartan teva,
• Lorista
• Losacor
• Karin
• Presartan,
• Maimaitawa.

Fom ɗin saki

launin rawaya, allunan murfin biconvex mai dauke da allunan, tare da farin (ko kusan fararen fata), farin ciki na aluminium ko fim na PVC, kwali na kwali

Abun aiki mai aiki

Potsafa ta Losartan (50, 100 MG)

Fitowa

Microcrystalline cellulose, sodium stearyl fumarate, anhydrous colloidal silicon dioxide (Aerosil), croscarmellose sodium, prosolv HD 90

Harshen Shell: titanium dioxide, microcrystalline cellulose, macrogol stearate, hypromellose

Pharmacodynamics

Losartan magani ne mai ƙima. Kasancewa wanda ba shi da peptide mai karɓa na masu karɓa na AT2, yana yin gasa da toshe masu karɓar AT1, yana hana angiotensin II dauri a kansu. Magungunan suna ƙaddamar da sakin vasopressin, catecholamines, aldosterone da renin, yana hana haɓakar hauhawar jijiya da hauhawar jini na ventricular. Ba shi da tasiri mai toshe hancin enzyme na angiotensin, ba ya tasiri da tsarin kinin-kallikrein, kuma baya barin bradykinin ya tara.

Metabolite mai aiki na Losartan, wanda aka kirkira akan aiwatar da canji na halitta, yana haifar da sakamako mai guba.

Pharmacokinetics

Bayan kulawa ta baka, ƙwayar (a cikin allurai har zuwa 200 MG) yana da kyau sosai, kuma, bayan tsarin metabolism, yana samar da metabolite na carbonxylic acid da ke yaduwa cikin jini. Tsarin bioavailability na Losartan shine 33%. Idan ana magana da baki, a cikin awa ɗaya sai ya zama mafi yawan ƙwayar jini, yana ɗaukar kashi 99% zuwa albumin. Ofimar rarraba shine lita 34. Bayan sa'o'i 3-4, C max ya isa metabolite na miyagun ƙwayoyi. Rabin rayuwar Losartan shine awanni 2, metabolite din da yake aiki shine 9 hours. Ana lura da tasirin antihypertensive matsakaici daga amfani da miyagun ƙwayoyi bayan makonni 2-4 daga fara gudanarwa a cikin marasa lafiya na kowane zamani, jinsi da launin fata.

Kashi 4% na kashi an cire shi ta hanyar kodan ba canzawa, 6% - a cikin nau'i na metabolite mai aiki. Bayan gudanar da baki, 35% na losartan ya fita tare da fitsari, 58% - tare da feces. Tare da aikace-aikacen guda ɗaya ba ya tara a jiki.

A cikin marasa lafiya na shekaru masu tasowa suna fama da hauhawar jijiyoyin jini, maida hankali kan abu mai aiki da ƙwaƙwalwar ƙwaƙwalwar mai aiki kusan ba ta bambanta da natsuwa ba cikin samari masu fama da hauhawar jini. A cikin mata, yawan ƙwayar cuta a cikin plasma ya ninka sau biyu cikin maza. Mayar da hankali na aiki na metabolite a cikin maza da mata yana daidai da matakin.

Menene losartan na?

• Mahimmancin hauhawar jijiya,
• Hauhawar jini a cikin jijiya da hauhawar jini a cikin hagu (don rage haɗarin cutar cuta da hana mace-mace),
• Rashin bugun zuciya na zuciya (azaman magani wanda shine ɓangaren haɗuwa da jiyya),
• Nephropathy na ciwon sukari wanda ke hade da proteinuria da hypercreatininemia a cikin marasa lafiya da nau'in ciwon sukari na II na mellitus.
• A matsayin magani don hadadden magani na antihypertensive far.

Contraindications

• Hypersensitivity / rashin haƙuri ga abubuwan na miyagun ƙwayoyi,
• Haihuwa da lactation
• Rashin hanta
• Fasawa (bushewa)
• Sabuntawar hyperkalemia,
• Glucose-galactose malabsorption, rashin haƙuri a cikin lactose, rashi lactase,
• Amfani da haɗin kai tare da aliskiren (idan akwai matsala na aikin keɓaɓɓen aiki ko ciwon sukari mellitus),
• Age zuwa shekaru 18.

Ya kamata a dauki Losartan tare da taka tsantsan a cikin halaye masu zuwa:

• ciwon zuciya abin da ya faru a gaban mai girma na koda gazawar,
• arrhythmias na barazanar rayuwa,
• Ciwon zuciya,
• Bilateral (tsanani keɓantacce) renal artery stenosis,
• hyperkalemia
• take hakkin ma'aunin ruwa -
• raguwa a cikin jirgi (kewaya jini),
• cututtukan mahaukacin kwakwalwa,
• na gazawar
• na mitral ko aortic stenosis,
• na farko hyperaldosteronism,
• angioedema,
• hana ciwon zuciya.

Sashi da gudanarwa

Marasa lafiya tare da hauhawar jijiyoyin jini, An sanya Losartan sau ɗaya a rana a 50 MG, ya kamata a sha magungunan ba tare da cin abinci ba, ba tare da taunawa da shan ruwa mai yawa ba. Idan babu tsammanin sakamako na warkewa, ana bada izinin sashi na yau da kullun zuwa 100 MG. Matsakaicin tasirin maganin yana tasowa bayan makonni 3-6 daga farkon amfani. Ana ba da shawarar mutane da ke ƙasa da ragewar kewaya jini ya ɗauki 25 MG kowace rana.

Tare da gazawar koda kuma ga tsofaffi, maganin yau da kullun ba a gyara ba. An nuna marasa lafiya da raunin zuciya yayin shan Losartan a farkon kashi na 12.5 MG. Don cimma manufar ƙwayar manufa (50 MG), ana buƙatar haɓakar hankali a hankali na tsawon makonni 2-3.

Game da aikin hanta mai rauni, ana buƙatar raguwa a cikin yawan maganin yau da kullun.

Hulɗa da ƙwayoyi

Magungunan ba sa hulɗa tare da warfarin, erythromycin, phenobarbital, cimetidine, digoxin.

Tare da yin amfani da lokaci guda tare da fluconazole ko rifampicin a cikin plasma, an lura da raguwa a cikin matakin metabolite mai aiki. Losartan yana da ikon haɓaka aikin diuretics, IAAF da masu hana tallatawa aiki.

Lokacin amfani dashi tare da diuretics na potassium ko tare da shirye-shiryen potassium, hyperkalemia na iya haɓaka (saka idanu akai-akai na matakin potassium a cikin jini ya zama dole).

Magungunan rigakafin ƙwayar cuta marasa lalacewa (gami da masu hana CO2 masu zaɓi) suna rage tasirin Losartan.

Side effects

• farin ciki, ciwon kai,
• rauni
• rashin bacci
• rage karfin jini
• Alamar tarin jini,
• samarin
• migraine
• myalgia
• dyspepsia, tashin zuciya, ciwon ciki,
• alamun cutar rashin bacci
• hepatitis da sauran cututtukan hanta,
• bushe mucosa na baka,
• eosinophilia, thrombocytopenia, anemia,
• hyperkalemia
• concentarin maida hankali akan kwayar halitta, urea, nitrogen saura,
• halayen rashin lafiyan fata
• angioedema,
• anaphylaxis,
• tashin hankali na gout,
• hanci.

Umarni na musamman

A cikin marasa lafiya tare da rage yawan zubar jini, (sakamakon akai-akai na amfani da tsawan kuzari), losartan na iya tayar da hawan jini. Sabili da haka, kafin fara magani tare da wannan magani, ya zama dole don kawar da abubuwan da suka faru, ko ɗaukar magani a cikin ƙananan allurai.

Marasa lafiya da ke fama da cututtukan hanta (mai saukin kai ko matsakaici) bayan amfani da wakili mai narkewa, maida hankali kan bangaren aiki da metabolite mai aiki ya fi yadda yake cikin mutane masu lafiya. A wannan batun, a cikin wannan halin, kuma kan aiwatar da aikin jiyya, ana buƙatar ƙananan allurai.

Idan akwai rauni na aiki na koda, ci gaban hyperkalemia (ƙara yawan taro a cikin jini) mai yiwuwa ne. Saboda haka, yayin aiwatar da aikin jiyya, ana buƙatar saka idanu akai-akai matakin wannan microelement.

Tare da gudanarwa na lokaci guda na magungunan da ke shafar tsarin renin-angiotensin a cikin marasa lafiya tare da renal stenosis (guda ɗaya ko mai gefe biyu), serum creatinine da urea na iya ƙaruwa. Bayan dakatar da maganin, yanayin yakan zama al'ada. A wannan halin, ya wajaba a gudanar da aikin gwaje-gwaje akai-akai game da matakin ma'aunin kwayoyin halittar jikin kodan.

Ba a gano bayani game da tasirin Losartan a kan ikon tuki mota ko yin aikin da ke buƙatar karuwar hankali da saurin halayen psychomotor ba.

Menene losartan

INN (sunan kasa da kasa mai zaman kansa) - Losartan. A cikin radar, rajista na miyagun ƙwayoyi, Losartan an rarrabe shi azaman ƙungiyar likitancin magungunan angiotensin 2 antagonists tare da tasirin gaske. Bayan gudanarwa, tasirin ya ci gaba har kwana guda, don haka likitan Lozartan da analogues ana amfani da su ta hanyar likitoci a matsayin hanya mafi inganci.

Magungunan ya ƙunshi kayan aikin asali da na taimako. Abubuwan da ke aiki na maganin, wanda ke taimakawa tabbatar da ingantaccen sakamako daga aikace-aikacen, shine Losartanum potassium, synonym for potassium losartan. Componentsarin abubuwan haɗin da suke yin aiki don haɗa abu mai aiki sun haɗa da:

• lactose monohydrate,
• magnesium stearate,
• povidone
• silloon silicon dioxide,
• microcrystalline cellulose,
• croscarmellose sodium.

Hanyar aikin

Hanyar aiwatarwa ta dogara da toshewar masu karɓar angiotensin mai 2. Abubuwan da ke aiki yana magance tasirin spasmodic akan tasoshin, yana tallafawa aikin tsokoki na zuciya. Glandar adrenal ta fara samarda aldosterone na hormone, raguwar hawan jini. Kari akan haka, losartan yana aiki azaman diuretic, yana taimakawa haɓaka fitowar ruwa daga jiki.

Uric acid da kuma sodium salts suna fitowa tare da fitsari, kuma salts din potassium da yakamata don aiki na yau da kullun yana aiki. Bayan allunan sun shiga ciki, sinadarin losartan potassium mai narkewa yana narkewa kuma yana shafar hanji. Bioavailability kusan kashi 33%. An isa ayi a cikin jini bayan awa 1-1.5. Rushewar miyagun ƙwayoyi yana faruwa a cikin hanta, an keɓance ta cikin hanji.

Alamu don amfani

Magungunan yana cikin rukunin magungunan da ba za a iya amfani da su ba tare da shawarar likita ba. Kwararren likita zai taimake ka ka zabi ingantaccen sashi, ka yi magana game da manyan abubuwan da ke haifar da illa da cutarwa. Don ƙayyade ko kuna buƙatar ganin mai ilimin hanyoyin kwantar da hankali, yakamata ku auna matsin lamba akai-akai kuma ku mai da hankali ga tunaninku.

Idan masu nuna alamun tonometer sun wuce 140 ta 90, kuma mutum yana jin saurin bugun zuciya, rauni, ciwon kai a cikin kwanaki 5-6, lallai ne a je ofishin likita sannan a zabi magani don hauhawar jini. Babban alamu don amfani sune:

• matakin farko na hauhawar jini,
• na kullum zuciya da jijiyoyin jini,
• nau'in ciwon sukari na 2 tare da proteinuria (don kare kodan),
• na kullum zuciya.

Amfani da miyagun ƙwayoyi na yau da kullun na iya rage haɗarin cutar cututtukan zuciya da yawan mace-mace a tsakanin marasa lafiya. Bugu da kari, ana amfani da losartan don hana bugun jini da kasala na zuciya a cikin marassa lafiyar da ke fama da tashin zuciya da hawan jini. Tare da taimakon wannan kayan aiki, ana yin shirye-shirye don dasawa da jijiyoyin koda. Wa'adin don magance cututtukan zuciya na rashin lafiya na faruwa bayan da wasu kwayoyi basu da tasiri.

Koyarwar losartan

Ana yin lissafin sashi da tsawon lokacin gudanarwa ta hanyar likitan ilimin likita dangane da umarnin. Methodsarin hanyoyi don ƙayyade hanyoyin dabarun magani suna tambayar mai haƙuri, bincika rikodin likita wanda ke nuna cututtukan cututtukan fata. Dangane da bayanin, idan an wajabta losartan a karon farko, kuna buƙatar ɗaukar rabin rabi don gano idan akwai rashin lafiyan ƙwayoyi. Ga kowace cuta, akwai tsarin tazara dabam.

Hawan jini

Lokacin da ake rubuta Losartan don maganin hauhawar jini bisa ga umarnin, ana bada shawara a sha Allunan ba tare da tauna ba, rubuta duk da amfani. A lokacin jiyya, kuna buƙatar saka idanu akan tasirin cutar ta amfani da ma'aunin matsa lamba na yau da kullun. Ya danganta da tsananin yanayin, an wajabta masu haƙuri su ɗauki 50 MG kowace rana. A hankali na mai ilimin hanyoyin kwantar da hankali, ana iya ƙara kashi zuwa matsakaicin darajar yau da kullun na 100 MG.

Rashin lafiyar zuciya

Don rage haɗarin rikicewa daga rashin zuciya, ana fara amfani da allunan Losartan tare da mafi ƙarancin adadin 12.5 mg / rana. Kowane mako, ana ninka kashi biyu. Don maganin kulawa da lalacewar zuciya kar a yi amfani da fiye da 50 MG kowace rana. Ana bada shawarar saka idanu akai-akai tare da mai lura da karfin jini don gujewa raguwa mai ƙarfi a cikin karfin jini.

Ana amfani da magungunan analogues na Losartan sun hada da magunguna waɗanda ke da tasirin kiwon lafiya iri ɗaya. Dukkansu sun ƙunshi abu mai kama da aiki. Losartan na asali ya bambanta kawai a bayyanar kunshin, nau'i na saki, sashi da kuma masana'anta. A wasu shirye-shirye, ana amfani da wasu kayan taimako.

An tsara magungunan maye gurbi idan an gano contraindications. Don tantance wanne irin magungunan da ya fi dacewa da hauhawar jini, kwararren likita ya kamata. Jerin analog ɗin ana amfani dasu da yawa sun haɗa da:

• Bugawa
• Lorista
• Lozap Plus,
• Maimaitawa
• Lozarel
• Vasotens,
• Brozaar
• Presartan,
• Lakea
• Zisakar
• Losartan Richter,
• Karzartan
• Hypothiazide,
• Losacor
• Karin
• Vero Losartan
• Losartan Canon.

Farashin losartan

Kudin losartan yayi ƙasa, yana cikin ɗayan magunguna masu araha don hauhawar jini. Farashin sa ya dogara da yankin da ake aiwatar da siyarwa, adadin allunan da ke kunshe a cikin kunshin. A cikin Moscow da St. Petersburg, zaku iya siyan magungunan cikin rahusa, ba kawai ta hanyar kantin magani ba, har ma ta kantin sayar da kan layi.

Abun ciki da nau'i na saki

• potassium losartan,
• magnesium stearate,
• titanium dioxide
• barasa polyvinyl,
• foda talcum.

Tsarin saki yana a cikin allunan suna da siffar zagaye mai zagaye, kuma a cikin foda mai lu'ulu'u. Suna da farin tint. Yawan kayan aiki mai aiki a kowace kwamfutar hannu shine 25, 50, 100 ml.

Aikin magunguna, magunguna

Lokacin shan magani, hawan jini ya fara raguwa a hankali, saboda wanda aka wajabta magunguna don nau'ikan hauhawar jini. ACE mai hanawa.

Da sauri ya daga hanjin narkewa. Matsakaicin sakamako yana faruwa awanni 6-7 bayan shan kwayoyin. Excretion - tare da feces da fitsari ba su canzawa. Rashin bioavailability na kayan aiki mai aiki shine kusan 65%. Yana ɗaukar nauyin sunadaran plasma da kashi 99%. Domin matsin lamba ya isa al'ada, ya zama dole a fara jinyar - akalla watanni 1-2.

An sanya maganin Losartan ba kawai don hauhawar jini ba, har ma don sauran cututtuka.

Hanyar aikace-aikacen, shawarar da aka ba da shawarar

Allunan ruwan lesartan ana wanke su da karamin ruwa. Foda ya narke cikin ruwa har sai an fasa lu'ulu'u. Ana iya ɗauka biyu kafin abinci da bayan. An saita sigogi a cikin kowane yanayi daban-daban ga kowane mai haƙuri.

Umarnin yana nuna shawarar dosages.

A kashi na farko, ana bada shawara don ɗaukar kashi 50 ml. Yana ci gaba da jiyya na gabaɗaya, idan yanayin marasa lafiya bai daskare ba. Tare da rashin isasshen aikin magani na miyagun ƙwayoyi, za a ninka kashi biyu. Idan babba ya dauki wasu kwayoyi wadanda ke rage karfin jini, an rage kashi zuwa 25 MG.

An tsara wa marasa lafiya da cutar hanta mai ƙima mafi ƙaranci (25 mg). A cikin rauni na zuciya - ba fiye da 12.5 MG ba. Ana gudanar da jiyya a cikin irin waɗannan lokuta a ƙarƙashin kulawar likita.

Wajibi ne a ɗauki allunan sau ɗaya a rana, a lokaci guda. Yana da mahimmanci a bi matakan da likitanku ya umarta don kauce wa yawan shaye-shaye da sakamako masu illa.

Ba a sanya yara magani ba. Idan irin wannan buƙatar ta taso, an wajabta ƙaramin matakin - 12.5 MG kowace rana.

Shigarwa yayin daukar ciki da shayarwa

Magungunan yana contraindicated a cikin daukar ciki, ko da kuwa ajalin. Kudin shiga na iya haifar da mutuwar tayi ko azzaluma. Rashin daidaituwa a cikin ci gaban tayin zai iya zama kamar haka: rashin ci gaba ƙasusuwa, hauhawar ƙarfi, zuciya.

A cikin lokacin lactation, abu mai aiki mai karfi ya shiga jikin yaro tare da madarar uwa. Sakamakon hakan cin zarafin narkewa ne, tashin zuciya, shimfidu kwance, fainti, da sauran rikice rikice.

Zai yiwu sakamako masu illa

• palpitations
• amai
• rashin lafiyan mutum
• hanawa daga cikin tsakiyar juyayi tsarin,
• Laryngeal edema,
• canji na canji (maƙarƙashiya, zawo),
• fata rashes,
• ciwon ciki
• kumburi da mucous membranes,
• raguwa cikin akidar gani,
• tashin zuciya
• fainting jihar
• angina pectoris
• bushe tari
• leukopenia
• rashin damuwa ga rana,
• ciwon kai
• nutsuwa
• rashin bacci
• karin ƙarfe
• rashin lafiyan rhinitis
• take hakkin dandano
• rarrabuwa a cikin kwakwalwa,
• gum mai jini
• kumburin hanta
• raguwa a cikin haemoglobin.

Idan mummunan halayen ya faru, an dakatar da maganin. Likita ya zabi wani magani.

Yin hulɗa tare da wasu kwayoyi

Sakamakon warkewa na losartan yayin shan diuretics ya fara ƙaruwa.

Haramun ne a yi amfani da wasu hanyoyi a lokaci guda, aikin wanda aka yi niyya don rage matsin lamba.

Magungunan yana kara tasirin magani na kwayoyi masu dauke da sinadarin potassium, wanda ke haifar da mummunan sakamako.

Amfani da ciki tare da magungunan marasa steroidal suna cutar da ƙodan. Ana buƙatar gwajin duban dan tayi.

Idan mai haƙuri ya ɗauki wasu ƙwayoyi, shawarar likita ta wajaba.

Farashin kuɗi a cikin kantin magani

Farashin ya dogara da marufi - daga 100 zuwa 500 rubles. Manyan marufi suna isa ga cikakken magani.

• Lozap,
• Alcadil
• Kapoten,
• Lorista
• Normio
• Zisakar
• Golten
• Kwayar cuta
• Hyperium
• Bugawa
• Kaptopres,
• Norton
• Kyaftin
• Epistron
• Maimaitawa
• Biosynthesis
• Bugawa.

Ra'ayoyi game da miyagun ƙwayoyi

Kyakkyawan magani don shirya maganin hauhawar jini a cikin tsofaffi da matasa marasa lafiya.Ya yi aiki a hankali da ƙarfi. Wajibi ne a lasafta tasirin magungunan, a gefe guda, babu sakewa kamar yadda aka soke enalapril. Tivationarfafawa marasa lafiya: cewa hadarin kamuwa da bugun zuciya ya ragu, wannan yana da matukar ban sha'awa ga marasa lafiya.

Ban ci karo da rashin yarda da sakamako masu illa ba a aikace.

Losartan magani ne mai kyau, mai tasiri don cutar hawan jini. Da sauri yana taimakawa komawa al'ada. A farashi, kayan aiki mai araha ne. Kamar yadda na sani, ba ya haifar da sakamako masu illa. Da kaina, na jimre shi da kyau. Ba a taɓa samun sakamako masu illa ba. Ya dauki hanya, ya taimaka sosai wajen kawar da hauhawar jini da nake yi tun ina ƙuruciya.

Marina Klimenko, Nizhnekamsk (haƙuri)

Bamu taba samun karfin jini ba. Amma kwanan nan, ya fara ƙaruwa koyaushe. Likita ya ba da magani tare da allunan lozartan. Sashi - don kwamfutar hannu duka. Halin nasa ya inganta bayan 'yan kwanaki, ko da yake kafin hakan, kansa ya kasance mai zafin rai. Matsin lambar ya dawo daidai bayan hanya. Babban farashi mai araha.

Halayen magunguna

A cikin umarnin Losartan, an lura cewa an sanya miyagun ƙwayoyi ga takamaiman maganin antagonensin II antagonists. Magungunan losartan, wanda yana da tasiri mai mahimmanci, yana rage juriya na gaba ɗaya na tasoshin jini.

Yana da alaƙa da rage karfin jini, rage matakan adrenaline da aldosterone a cikin jini, da rage nauyin a kan ƙwayar zuciya, haka kuma a samar da tasirin diuretic. Losartan yana taimakawa haɓaka haƙuri a cikin marasa lafiya tare da alamun raunin zuciya, kuma yana hana haɓakar hauhawar myocardial.

Umarnin likita don amfani

A wani matsin lamba ne wajabta losartan? Marasa lafiya tare da hauhawar jijiyoyin jini, An sanya Losartan sau ɗaya a rana a 50 MG, ya kamata a sha magungunan ba tare da cin abinci ba, ba tare da taunawa da shan ruwa mai yawa ba. Idan babu tsammanin sakamako na warkewa, ana bada izinin sashi na yau da kullun zuwa 100 MG. Matsakaicin tasirin maganin yana tasowa bayan makonni 3-6 daga farkon amfani. Ana ba da shawarar mutane da ke ƙasa da ragewar kewaya jini ya ɗauki 25 MG kowace rana.

Tare da gazawar koda kuma ga tsofaffi, maganin yau da kullun ba a gyara ba. An nuna marasa lafiya da raunin zuciya yayin shan Losartan a farkon kashi na 12.5 MG. Don cimma manufar ƙwayar manufa (50 MG), ana buƙatar haɓakar hankali a hankali na tsawon makonni 2-3.

Game da aikin hanta mai rauni, ana buƙatar raguwa a cikin yawan maganin yau da kullun.

Yi amfani da lokacin daukar ciki da lactation

Yin amfani da miyagun ƙwayoyi losartan lokacin daukar ciki yana contraindicated. An san cewa kwayoyi da suka shafi tsarin renin-angiotensin-aldosterone kai tsaye (RAAS), lokacin da aka yi amfani da su a cikin kashi na 2 da na 3 na ciki, na iya haifar da lahani na haɓaka ko ma mutuwar tayi. Sabili da haka, lokacin da ake bincika ciki, ya kamata a dakatar da Losartan nan da nan.

Ba a sani ba ko losartan tare da madara mai nono keɓe. Ba'a ba da shawarar shan ƙwayar miyagun ƙwayoyi a lokacin lactation. Idan shan Losartan ya zama dole yayin lactation, to dole ne a dakatar da shan mama.

Yadda ake ɗaukar yara?

Contraindicated a cikin yara da matasa a karkashin shekara 18.

1. Bugawa
2. Brozaar
3. Vasotens,
4. Vero Losartan
5. Zisakar
6. Cardomin Sanovel,
7. Karzartan
8. Cozaar
9. Lakea
10. Lozap,
11. Lozarel
12. Losartan kannanan,
13. Losartan Richter,
14. Losartan teva,
15. Lorista
16. Losacor
17. Karin
18. Presartan,
19. Maimaitawa.

Lokacin zabar analogues, dole ne a tuna cewa umarnin don amfani da losartan, farashin da sake dubawa na kwayoyi irin wannan ba su amfani ba. Sauya maganin yana halatta kawai bayan shawarar likita.

Menene sake dubawa suke magana akai?

Ainihi, sake dubawa game da wannan magani tabbatacce ne, wanda ke tabbatar da amfanin amfani da maganin. Koyaya, akwai kuma sake dubawa, galibi game da Losartan Richter, inda mutane ke korafi game da bayyanar sau da yawa game da tasirin sakamako. Ya kamata a faɗi cewa mummunan sakamako yana faruwa ne bayan allurai da yawa na wannan magani.