MULKIN MV

Glyclazide MB shiri ne na magana da bakin mutum wanda ya danganta da asalin abubuwan da ke faruwa a zamanin na 2. Magani:

1. yana ƙarfafa haɓakar insulin,
2. yana haɓaka tasirin insulin-secretory na glucose,
3. lowers sukari jini
4. yana ƙara ƙarfin jijiyar insulin a cikin kasusuwa na gefe,,
5. normalizes matakin azumi glycemia,
6. yana rage samarwar glucose,
7. ban da shafar metabolism, ƙwayoyin suna inganta microcirculation.

Glyclazide yana rage haɗarin ƙwanƙwasa jini a cikin ƙananan tasoshin, yana shafar hanyoyin guda biyu lokaci guda waɗanda ke haɗu da haɓaka rikice-rikice na ciwon sukari mellitus:

• m hanawa na platelet mannewa da tarawa,
• domin murmurewa
• don rage dalilan kunnawa platelet (thromboxane B_2, beta thromboglobulin).

Contraindications

• nau'in ciwon sukari guda 1
• babban hankali ga Glyclazide ko kuma abubuwan da ke tattare da ƙwayar (zuwa ga sulfonamides, zuwa abubuwan da suka samo asali na sulfonylurea),
• ciki da lactation
• m hanta ko koda gazawar,
• shan miconazole,
• masu fama da cutar sankara
• maganin ciwon sukari
• mai ciwon sukari ketoacidosis,
• shekaru zuwa shekaru 18
• karancin lactase
• rashin daidaituwa na lactose,
• Likitoci ba su bada shawarar yin amfani da maganin a lokaci daya tare da danazol ko phenylbutazone.

Yaushe yakamata a dauke shi da taka tsantsan

Ba za a iya yin amfani da Gliclazide ba tare da takardar izinin likita, tunda magani bai dace da kowa ba. Ga jerin yanayi waɗanda dole ne a yi amfani dasu da taka tsantsan:

1. rashin daidaitawa ko rashin daidaitaccen abinci mai gina jiki,
2. tsufa
3. hawan jini
4. pituitary ko adrenal kasawa,
5. mummunan cututtuka na tsarin zuciya da jijiyoyin jini (atherosclerosis, cututtukan zuciya),
6. kyakyawan magana,
7. maganin glucocorticosteroid na tsawon lokaci,
8. hanta ko gazawar koda,
9. rashin ƙarfi na glucose-6-phosphate,
10. barasa

Kula! An wajabta magunguna kawai don manya!

Yadda ake shan ciki yayin shayarwa da shayarwa

Babu bayanai game da amfani da miyagun ƙwayoyi a lokacin lokacin haihuwar. Bayanai game da amfani da wasu abubuwan da aka samo na sulfonylurea yayin daukar ciki yana iyakantacce.

A cikin nazarin dakin gwaje-gwaje a kan dabbobi, ba a gano tasirin teratogenic na miyagun ƙwayoyi ba. Don rage haɗarin rikice-rikice na haihuwar haihuwa, kuna buƙatar ingantaccen iko game da ciwon sukari mellitus (ilimin da ya dace).

Mahimmanci! Magungunan maganin hana daukar ciki na haila yayin haila ba a sanya su ba. Don lura da ciwon sukari yayin daukar ciki, an zaɓi maganin insulin. Amincewa da magunguna na hypoglycemic ana bada shawara don maye gurbinsu da ilimin insulin.

Haka kuma, wannan doka ta shafi karar lokacin da ciki ya faru a lokacin shan miyagun ƙwayoyi, kuma idan ciki ya kasance yana kunshe ne a cikin shirin matar.

Ganin cewa babu bayanai game da shan kwayoyi a cikin madara, ba a cire haɗarin haɓakar haɓakar fetir. Dangane da haka, yin amfani da Gliclazide yayin shayar da jarirai nono.

Umarnin da sashi

30 MG allunan da aka yiwa gyaran fuska yakamata a sha sau 1 a rana a karin kumallo. Idan mai haƙuri ya karbi wannan magani a karo na farko, kashi na farko ya kamata ya zama 30 MG, wannan shima ya shafi mutane sama da 65 shekaru. Sannu a hankali canza sashi har sai lokacin da ake buƙatar warkewarta ta bayyana.

An zabi zabi na kashi gwargwadon matakin sukari a cikin jini bayan farkon jiyya. Za'a iya ɗaukar kowane canjin kashi na gaba kawai bayan sati biyu.

Ana iya maye gurbin Glyclazide MB tare da allunan Glyclazide tare da fitarwa na yau da kullun (80 MG) a cikin kullun na 1-4 guda. Idan saboda wasu dalilai mara lafiya ya rasa magunguna, kashi na gaba kada ta kasance mafi girma.

Idan ana amfani da allunan Glyclazide MB 30 MG don maye gurbin wani magani na hypoglycemic, ba a buƙatar lokacin juyawa a wannan yanayin. Abin sani kawai kawai don kammala cin abincin yau da kullun na maganin da ya gabata kuma kawai gobe don ɗaukar Gliclazide MB.

Mahimmanci! Idan an yi maganin mara lafiyar a cikin maganin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa tare da tsawon rabin rayuwa, saka idanu a hankali game da tattarawar glucose a cikin jini ya zama dole don makonni 2.

Wannan ya zama dole don kauce wa haɓakar haɓaka, wanda na iya kasancewa yana faruwa akan asarar tasirin maganin da ya gabata.

Za'a iya haɗuwa da miyagun ƙwayoyi tare da inhibitors alpha-glucosidase, biguanides ko insulin. Marasa lafiya tare da gazawar matsakaici mara kyau ko matsakaiciyar matsakaici, Gliclazide MB an tsara shi a cikin allurai iri ɗaya kamar yadda marasa lafiya tare da kyakkyawan aiki na renal. An sanya ƙwayar maganin cikin lalacewa ta rashin ƙarfi.

Marasa lafiya a cikin haɗarin cutar hypoglycemia

Marasa lafiya suna cikin haɗarin haɓakar haɓakar jini:

1. rashin daidaituwa ko rashin abinci mai gina jiki,
2. tare da raunin da ya rama ko mummunan cuta na endocrine (hypothyroidism, adrenal da pituitary insufficiency),
3. tare da rusa mahaukatan jini bayan an tsawaita musu,
4. tare da haɗari na cututtukan zuciya da jijiyoyin jini (na atherosclerosis na kowa, carotid arteriosclerosis, cututtukan zuciya da jijiyoyin jini),

Ga irin waɗannan marasa lafiya, an tsara maganin Glyclazide MB a cikin ƙananan allurai (30 MG).

Side effects

Magungunan zai iya haifar da glycemia, wanda bayyanar cututtuka ke nunawa:

• yunwa
• gajiya, rauni mai rauni,
• ciwon kai, tsananin farin ciki,
• karuwar gumi, rawar jiki, paresis,
• farhythmia, palpitations, bradycardia,
• hawan jini
• rashin bacci, bacci,
• haushi, damuwa, tashin hankali, bacin rai,
• tashin hankali
• mai da hankali taro,
• jinkirin amsawa da rashin iya maida hankali,
• rikicewar azanci
• karancin gani
• aphasia
• asarar kamun kai
• jin rashin taimako
• m numfashi
• katsewa
• delirium
• asarar sani, coma.

1. erythema
2. fata tayi
3. cututtukan mahaifa
4. itching da fata.

Akwai sakamako masu illa daga narkewa:

• ciwon ciki
• kamuwa da gudawa
• tashin zuciya, amai,
• da wuya cholestatic jaundice hepatitis, amma suna buƙatar cire magani nan da nan.

Yawan damuwa da hulɗa

Tare da rashin isasshen ƙwayar cuta, da yiwuwar haɓaka yanayin ciwo mai ƙarfi, wanda zai iya haɗuwa da raunin jijiyoyin jiki, raɗaɗi, ƙwayar cuta. A bayyanar farko na waɗannan alamun, mai haƙuri yana buƙatar asibiti mai gaggawa.

Idan ana zargin ko cutar ta haihuwar hypoglycemic, ana gudanar da maganin 40-50% na dextrose na cikin haƙuri ga mai haƙuri. Bayan haka, sun sanya dropper tare da bayani na 5% dextrose, wanda ya zama dole don kula da daidaitaccen glucose a cikin jini.

Bayan mai haƙuri ya sake farkawa, don guje wa maimaita yawan zubar jini, dole ne a ba shi abinci mai wadatacce a cikin ƙwayoyin carbohydrates masu sauƙin narkewa. Wannan ya biyo bayan saka idanu sosai akan matakan sukari na jini da sanya idanu akai-akai na haƙuri a cikin awanni 48 masu zuwa.

Actionsarin ayyuka, dangane da yanayin mai haƙuri, ƙwararren likita ne ya yanke shawarar. Saboda ƙayyadadden ikon ɗaukar magungunan ga ƙwayoyin plasma, dialysis ba su da tasiri.

Glyclazide yana haɓaka tasiri na maganin anticoagulants (warfarin), kawai yanayin shine maiyuwa ku buƙaci daidaita sashin maganin anticoagulant.

Danazole tare da Gliclazide sakamako ne na masu ciwon sukari. Dukansu yayin amfani da danazol da kuma bayan an cire ta, ana buƙatar sarrafa glucose da kuma daidaita yanayin Glyclazide.

Gudanar da tsarin na phenylbutazone yana haɓaka tasirin sakamako na Gliclazide (yana rage jinkirin motsa jiki daga jiki, ƙaura daga sadarwa tare da kariyar jini). Ana buƙatar saka idanu na Glyclazide da saka idanu na glucose na jini. Dukansu a lokacin shan phenylbutazone, da kuma bayan cirewa.

Tare da tsarin kulawa na Miconazole kuma lokacin amfani da gel a cikin ƙwayar bakin, yana haɓaka tasirin hypoglycemic na miyagun ƙwayoyi, har zuwa haɓakar ƙwayar cuta.

Ethanol da abubuwanda ke haifar da haɓakawar hypoglycemia, na iya haifar da haɓakar ƙwaƙwalwar ƙwayar cuta.

Lokacin da aka yi amfani dashi a hade tare da sauran magungunan hypoglycemic (biguanides, acarbose, insulin), fluconazole, beta-blockers, H2-histamine recepor blockers (cimetidine), angiotensin-canza enzyme inhibitors (enalapril, captoprilamide antioxidants, non-steroidal sulfide inhibitors Tasirin hypoglycemic, bi da bi, hadarin cutar rashin ruwa.

Chlorpromazine a cikin manyan allurai (fiye da 100 mg / rana) yana ƙaruwa da yawan haɗuwar glucose a cikin jini, yana hana ɓoye insulin. Dukansu yayin amfani da chlorpromazine kuma bayan an cire ta, ana buƙatar sarrafa glucose da canji a cikin kashi na Gliclazide.

GCS (rectal, na waje, intraarticular, amfani da tsarin) ƙara yawan sukarin jini tare da yiwuwar ci gaban ketoacidosis. Dukansu yayin amfani da GCS da kuma bayan an cire su, ana buƙatar sarrafa glucose da canji a cikin kashi na Gliclazide.

Terbutaline salbutamol, erythrocytes na ciki - haɓaka sukari na jini. Ana buƙatar sarrafa glucose a cikin jini kuma, idan ya cancanta, sauyawa zuwa ilimin insulin.

Shawarwarin musamman da sakin sakin layi

Magungunan Gliclazide MB yana da inganci kawai a hade tare da rage yawan kalori, wanda ya ƙunshi ƙananan adadin carbohydrates. Ana buƙatar saka idanu na yau da kullun game da yawan glucose, duka a kan komai a ciki da bayan abinci, ana buƙatar. Wannan yana da mahimmanci musamman a matakin farko na jiyya.

Yayin yin magani tare da miyagun ƙwayoyi, don kauce wa raunin da ya faru da haɗari a kan hanya, ana ba da shawarar don gujewa tuki motocin da aiki tare da kayan haɗari waɗanda ke buƙatar mai da hankali sosai da saurin amsawa.

Allunan 30 MG, an tattara su cikin blister of 10 guda.

Rayuwar shiryayye na Gliclazide shine shekaru 3, bayan wannan ba za'a iya amfani dashi ba. Ya kamata a adana maganin a cikin busassun wuri, duhu mai sanyi, mara amfani ga yara.

A cikin yankuna daban-daban na ƙasar, farashin magani ya bambanta daga 120 zuwa 150 rubles. Muna magana ne game da fakitoci waɗanda ke ɗauke da allunan 60. Akwai marufi a cikin gwangwani polymer. An saka gilashi ɗaya ko 1 zuwa 6 a cikin kwalin kwali.

Bambanci a farashin ya dogara da dalilai daban-daban: masana'anta, yanki, matsayin kantin magani.

Hanyar aikace-aikace

Don sarrafawa na baka. Magunguna Gliclazide MV An yi niyyar magani ne kawai.
Yawan kowace rana na MV Glyclazide na iya bambanta daga 30 MG zuwa 120 MG. An ba da shawarar shan 1 sau ɗaya a rana yayin karin kumallo, haɗiye allunan gaba ɗaya ba tare da tauna ba.
Idan kun tsallake shan magani, ba za ku iya ƙara yawan kashi ba gobe.!
Kamar yadda yake tare da sauran magunguna na hypoglycemic, ana buƙatar zaɓin wannan maganin a kowane yanayi daban, gwargwadon halayen metabolic na mai haƙuri.
Yankin da aka ba da shawarar farko shine 30 MG (1 kwamfutar hannu 1 na Gliclazda MV tare da sashi na 30 MG ko allunan 1 2 tare da sashi na 60 MG).
Game da ingantaccen iko na matakan glucose na jini, ana iya amfani da wannan kashi azaman magani na kulawa.
Idan babu cikakken iko na matakan glucose, ana iya ƙara yawan kashi zuwa 60 mg, 90 mg ko 120 mg kowace rana. Matsakaici tsakanin ƙaruwa mai nasara a cikin adadin ƙwayar ya kamata ya zama aƙalla wata 1, sai dai idan matakan glucose na jini ba su raguwa bayan makonni biyu na maganin. A irin waɗannan halayen, ana iya ƙara yawan kashi biyu makonni bayan fara magani.
Matsakaicin da aka bayar da shawarar kullun shine 120 MG.
60aya daga 60 MG Glyclazide MV an gyara kwamfutar hannu saki yana daidai da biyu 30 MG Gliclazide MV gyara allunan saki. Gilashin Glyclazide MV 60 MG 60 wanda aka canza-aka saki kwamfutar hannu yana da sauƙin rarrabuwa, wanda ke ba da damar daidaita magungunan.
Yi amfani dashi a hade tare da sauran magungunan maganin antidi
Ana iya amfani da Gliclazide MB a hade tare da biguanidines, alhib-glucosidase inhibitors ko insulin. Ga marasa lafiya waɗanda ba su da cikakken iko a cikin glucose na jini ta hanyar ɗaukar Glyclazide MV, ana iya tsara allurar insulin a ƙarƙashin kulawa ta kusa da likita.
Tsofaffi mutane
Shawarwarin da aka ba da shawarar ga tsofaffi iri ɗaya ne ga waɗanda ke cikin manya waɗanda ba su cika shekara 65 ba.
Rashin wahala
Shawarar magungunan da aka ba da shawara ga gazawar sassaucin rauni mai sauƙi zuwa matsakaici mai tsanani daidai ne ga waɗanda keɓaɓɓu da aikin keɓaɓɓiyar al'ada.
Marasa lafiya tare da haɓakar haɗarin hypoglycemia: tare da rashin abinci mai gina jiki, tare da raunin endocrine mai raɗaɗi ko mara kyau (hypopituitarism, hypothyroidism, raunin hormone adrenocorticotropic),
-bayan sakewa na tsohuwar baya da / ko tazara mai yawa corticosteroid far, a cikin cututtukan jijiyoyin bugun zuciya (cututtukan zuciya mai raunin gaske, matsanancin jijiya carotid, toshewar jijiyoyin jijiyoyin jiki).
An ba da shawarar yin amfani da kwayoyi tare da mafi ƙarancin yau da kullun na farko na 30 MG.

Side sakamako:
Jiyya Glyclazide MV na iya haifar da hauhawar jini a cikin yanayin rashin abinci na yau da kullun musamman a lokacin tsallake abinci.
Bayyanar alamun alamomin hypoglycemia: ciwon kai, matsananciyar yunwar, tashin zuciya, amai, gajiya, damuwa, bacci, matsananciyar damuwa, rashin hankali sosai, raguwar ikon tantance halin da ake ciki da jinkirtawa, bacin rai, ruhi mai haske, raunin gani da magana, tashin hankali, tashin hankali, tashin hankali, tashin hankali, tashin hankali, tashin hankali, rashin hankalin gani, tashin hankali, magana, tashin hankali, tashin hankali, tashin hankali, tashin hankali. , paresis, raguwar hankali, rashi, jin kai na rashin taimako, asarar kamun kai, halin rashin hankali, matsewar ciki, numfashi mara nauyi, bradycardia, nutsuwa da asarar hankali, wanda hakan kan iya haifar dashi Wanke ko yin m.

Bugu da kari, alamun adrenergic counterregulation kamar sweating, clammy skin, tashin hankali, tachycardia, hawan jini, bugun zuciya, angina pectoris da cardiac arrhythmia na iya faruwa.
Yawancin lokaci waɗannan alamun suna ɓacewa bayan shan carbohydrates (sukari). A lokaci guda, masu kayan zahiri basu da wannan tasiri.
A cikin mummunan hare-hare da haɓakawa na hypoglycemia, koda za a iya kawar da shi na ɗan lokaci tare da sukari, yana da gaggawa don ba da kulawa ta likita ko, idan ya cancanta, har ma asibiti.
Sauran tasirin da ba'a so:
rikice-rikice na tsarin gastrointestinal (tashin zuciya, zawo, jin wani nauyi a ciki, maƙarƙashiya, ciwon ciki, amai, tashin zuciya). Wadannan bayyanar cututtuka ba su da yawa tare da alƙawarin Gliclazide MV yayin karin kumallo.
Da wuya rahoton sakamako masu illa:
halayen rashin lafiyan: itching, urticaria, maculopapular fiska,
daga tsarin hematopoietic da lymphatic: canje-canje na jini. Wannan na iya zama anemia, leukopenia, thrombocytopenia, granulocytopenia. Yawancin lokaci, waɗannan alamun suna ɓacewa bayan kun daina shan magani,
rikicewar hanta da ciwon ciki: haɓaka ayyukan enzymes na "hanta" (aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase), hepatitis (lokuta da kebe).Idan cutar yolestice ta faru, ya kamata a dakatar da magani. Yawancin lokaci, waɗannan alamun suna ɓacewa bayan kun daina shan magani,
rikicewar ophthalmological: raunin gani na lokaci.

Yin hulɗa tare da wasu kwayoyi

Wani lokaci ya zama dole don daidaita sashin maganin antidiabetic a lokacin da bayan danazol.
Yana iya zama dole don daidaita sashi na maganin antidiabetic a lokacin da kuma bayan kammala mulkin danazol.
Haɗuwa yana buƙatar kulawa ta musamman.
Chlorpromazine: a cikin allurai masu yawa (fiye da 100 MG kowace rana) yana ƙara yawan glucose na jini, yana rage ɓoye insulin.
Glucocorticosteroids (gudanarwa na tsarin mulki da na Topical: intraarticular, fata da shugaban rectal) da tetracosactrin suna haɓaka matakan glucose na jini tare da yuwuwar ci gaban ketoacidosis (rage haƙuri na carbohydrate ta glucocorticosteroids).
Progestogens: Sakamakon ciwon sukari na yawan allurai na progestogens. β-2-adrenostimulants - ritodrin, salbutamol, terbutaline: (amfani da tsari): ƙara yawan glucose.
Ba da kulawa ta musamman kan mahimmancin kulawa da kai na glucose jini. Idan ya cancanta, canja wurin haƙuri zuwa insulin far.
Idan kuna buƙatar amfani da haɗuwa da ke sama, kuna buƙatar kulawa ta musamman don sarrafa matakan glucose na jini. Yana iya zama mahimmanci don ƙara yawan sashi na MV Glyclazide duka yayin aikin haɗin gwiwa da kuma bayan dakatar da ƙarin magani.
Hadin gwiwa don yin la’akari.
Amincewa da shirye-shiryen maganin anticoagulant (warfarin): liyafar abubuwan da ke haifar da maganin sulfonylurea na iya haɓaka tasirin anticoagulant na irin waɗannan shirye-shiryen. Ana iya buƙatar daidaita sakin Anticoagulant.

Tasiri kan iya tuka motoci da hanyoyin sarrafa abubuwa:
Marasa lafiya shan Gliclazide MV, yakamata a lura da alamun hypoglycemia da amfani da taka tsantsan yayin tuki ko yin aiki da ke buƙatar ƙimar yawan motsa jiki da tunani.

Yanayin ajiya

A cikin wurin da aka kiyaye shi daga danshi da haske a zazzabi da bai wuce 25 ° C ba.
Ayi nesa da isar yara.

Ranar cikawa:
Don sashi na 30 MG, rayuwar shiryayye shine shekara 1.
Don sashi na 60 MG, rayuwar shiryayye shine shekaru 2.
Kada kayi amfani bayan ranar karewa wanda aka nuna akan kunshin.

Fom ɗin saki

Magunguna Gliclazide MV bayar a cikin hanyar taka gyara canjin damar:
Allunan zagaye na farin ko kusan fararen launi tare da sifar silima tare da bevel (sashi na 30 MG).
Allunan zagaye na farin ko kusan fararen launi tare da sifar silima tare da ɗimin ɗima da haɗari (sashi na 60 mg).
Allunan 10 a cikin fakiti mai laushi. Fayiloli uku ko shida, tare da umarni don amfani a cikin fakitin kwali.